Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_004636365Cyc: Bordetella pertussis J375 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari

glutathione phosphate phosphate phosphate phosphate glycine betaine pro dCTP dCTP dCTP pro predicted predicted ABC ABC RS08670 RS06240 RS11810 transporter RS16925 RS13500 RS12375 transporter RS11480 RS13985 of glutathione of phosphate

dCTP dCTP dCTP glycine betaine phosphate phosphate phosphate pro pro glutathione phosphate

Amino Acid Degradation Amino Acid Biosynthesis Degradation/ Hormone Biosynthesis Utilization/ 3-(all-trans- 1-cis-vaccenoyl- UDP-N-acetyl-α-D-muramoyl- 1-stearoyl- a mature 1-myristoyl- 1-stearoyl- a [glutamine- (S)-1-pyrroline- 1-myristoyl- 1-palmitoyl- L-valine degradation I L-leucine degradation I L-proline degradation Assimilation - Other D-alanyl-D-alanine a peptidoglycan 3-phenyl-2- 1-(18-hydroxyoleoyl)- hydroxypyruvaldehyde 2-phosphoglycolate hydantoin (2E,6E)-farnesyl superpathway of L- indole-3-acetate Fermentation mixed acid fermentation L-threonine L-alanyl-γ-D-glutamyl-L-lysine an oleoyl-[acp] sn-glycerol peptidoglycan a palmitoleoyl-[acp] sn-glycerol a stearoyl-[acp] sn-glycerol tyr nonaprenyl) sn-glycerol- 5-carboxylate sn-glycerol sn-glycerol met L-histidine biosynthesis superpathway of aromatic amino acid biosynthesis L-alanine superpathway of branched chain amino acid biosynthesis L-arginine biosynthesis I (via L-ornithine) L-lysine biosynthesis I alanine racemization L-glutamate acrylonitrile synthetase]- ATP oxopropanoate sn-glycrol 3-phosphate phosphate diphosphate isoleucine biosynthesis I L-isoleucine degradation I degradation I N-acetylmuramoyl- 3-phosphate (meso- 3-phosphate 3-phosphate benzene-1,2-diol phosphoglycolate hydantoinase/ 3-phosphate trifunctional 3-phosphate 3-phosphate amino-acid N- biosynthesis II L-arginine biosynthesis II (acetyl cycle) biosynthesis II biosynthesis degradation I bifunctional UDP-N- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- L-tyrosine aspartate/ bifunctional 2- 1-acyl-sn-glycerol- aldehyde 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- presqualene val L-alanine amidase: diaminopimelate bifunctional [glutamate- phosphatase: oxoprolinase transcriptional acetyltransferase: D-erythrose IV (bacteria) phosphoenolpyruvate leu pro acetylmuramoyl-L- 3-phosphate lytic 3-phosphate 3-phosphate tyrosine/aromatic polyprenyl-6- 3-phosphate dehydrogenase: 3-phosphate 3-phosphate 3-phosphate diphosphate oxaloacetate PRPP pyruvate C4H07_RS12290 -ammonia ligase]- C4H07_RS02985 family protein: pyruvate thr glu asp N-acetylglutamyl- ala (indole-3-yl) thr alanyl-D-glutamate-- acyltransferase: containing)transglycosylase acyltransferase: acyltransferase: aminotransferase: hydroxyphenol acyltransferase: C4H07_RS10955 acyltransferase: regulator/proline acyltransferase: acyltransferase: C4H07_RS11725 synthase aspartate/ 4-phosphate 2-oxoglutarate branched-chain ile trifunctional acrylonitrile N-acetylmuramoyl- adenylyl-L-tyrosine C4H07_RS15520 alanine aspartate kinase: phosphate bifunctional alanine racemase/ Glu/Leu/Phe/Val acetonitrile branched-chain threonine L-arginine degradation 2, 6-diaminopimelate C4H07_RS00195 domain-containing C4H07_RS00195 C4H07_RS00195 C4H07_RS10425 methylase/3- C4H07_RS00195 HAD family C4H07_RS00195 dehydrogenase/L- C4H07_RS00195 C4H07_RS00195 HpnD: hpnD thr RS19015 thr tyrosine/aromatic ATP 3-deoxy-7- acetolactate amino acid branched-chain transcriptional phosphorylase/ aldehyde bifunctional transaminase: threonine amino-acid N- pyruvate kinase: pyk phosphoenolpyruvate amino acid ammonia-lyase: II (AST pathway) ligase MurE/UDP- L-alanine amidase: demethylubiquinol 3- hydrolase: hydantoinase/ glutamate gamma- aminotransferase: phosphoribosyltransferase synthase C4H07_RS08910 amino-acid N- tRNA (adenosine(37)-N6)- dehydrogenase: Aminoacyl-tRNA Charging transaminase: regulator/proline 1-acyl-sn-glycerol- protein: 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- [glutamate-- aspartate/ 1-acyl-sn-glycerol- dehydrogenase 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- glutamate N- squalene phosphoheptulonate C4H07_RS05660 ammonia-lyase: carboxylase: transaminase: amino acid C4H07_RS18630 C4H07_RS15095 semialdehyde large subunit: acetyltransferase: acetyltransferase: threonylcarbamoyltransferase C4H07_RS08635 (indol-3-yl) C4H07_RS15400 N-acetylmuramoyl- 3-phosphate C4H07_RS03970 3-phosphate 3-phosphate tyrosine/aromatic O-methyltransferase 3-phosphate family protein: oxoprolinase 3-phosphate 3-phosphate 3-phosphate acetyltransferase/ synthase C4H07_RS05255 regulatory subunit: synthase AroG: aroG L-aspartyl-4-phosphate C4H07_RS18790 C4H07_RS16665 transaminase: dehydrogenase/L- acrylamide ditrans,octacis- a mature ammonia-ligase] dehydrogenase: ala C4H07_RS15400 C4H07_RS11725 C4H07_RS11725 complex ATPase subunit type acetamide C4H07_RS16665 arg tripeptide--D-alanyl-D- acyltransferase: acyltransferase: acyltransferase: 2-methoxy- UbiG: ubiG C4H07_RS18065 glycolate family protein: amino-acid HpnC: hpnC an oxidized [+ 2 isozymes] C4H07_RS10770 3-deoxy-D-arabino- C4H07_RS07655 glu tRNA charging pyruvate branched-chain C4H07_RS16665 threonine glutamate gamma- a peptidoglycan undecaprenyldiphospho- peptidoglycan [+ 2 isozymes] adenylyltransferase: aminotransferase: acyltransferase: acyltransferase: acyltransferase: acyltransferase: 1 TsaE: C4H07_RS18625 gln branched-chain alanine ligase MurF: murF C4H07_RS15950 putA heptulosonate [+ 8 isozymes] threonine bifunctional bifunctional N-acetyl-gamma- amidase: glutaminyl-tRNA ammonia- semialdehyde amidase: pentapeptide N-acetyl-(N- C4H07_RS182551-stearoyl-2- C4H07_RS18255 C4H07_RS18255 a [glutamine glnE 3-(4-C4H07_RS05255 6-(all-trans- 1-[18-hydroxyoeoyl]-2-C4H07_RS18255 3-phosphooxypyruvate C4H07_RS18255 C4H07_RS18255 C4H07_RS18255 acetyltransferase squalene O c-type asp ATP aspartate- amino acid branched-chain UDP-N-acetyl-α-D-muramoyl-L-alanyl- with (L-alanyl- a mature 1-myristoyl-2- 1-stearoyl-2- 1-cis-vaccenoyl- 1-myristoyl-2- 1-palmitoyl-2- 2 cytochrome ammonia- glutamate N- glutamyl-phosphate [+ 2 isozymes] biosynthesis via transamidation oxaloacetate amino acid C4H07_RS19220 nonaprenyl)phenol L-glutamate ArgJ: argJ cytochrome 7-phosphate glutamate N- C4H07_RS19220 lyase, dehydrogenase: 2 γ acetylglucosaminyl)muramate acyl-carrier protein oleoyl-sn-glycerol γ-D-glutamyl- synthetase]-O phe hydroxyphenyl) [18-hydroxy-lioleoyl]-sn N-carbamoylglycine 2-palmitoleoyl- palmitoleoyl- palmitoleoyl- phosphoribosyltransferase: semialdehyde arginine-- aminotransferase: amino acid N -succinyl- -D-glutamyl-L-lysyl-D-alanyl-D-alanine peptidoglycan palmitoleoyl- stearoyl-sn c oxidase a reduced (S)-2-acetolactate lyase, D-ala D-lactate aminotransferase: acyl-carrier protein acyl-carrier protein 4 gamma- N-acetyl-L- C4H07_RS19455 3-dehydroquinate acetyltransferase/ dehydrogenase: acetyltransferase/ reductase: [+ 11 isozymes] arg C4H07_RS17395 biosynthetic: putA [+ 11 isozymes] 3-phosphate meso-2,6- strand (non- sn-glycerol -glycerol 3- -(5'-adenylyl) pyruvate -glycerol 3-phosphate sn-glycerol- sn-glycerol sn-glycerol H O c-type aspartate kinase: tRNA ligase: dehydrogenase: Ldh family C4H07_RS17395 4-methyl-2- aminotransferase: (S)-1-pyrroline- L-arginine methionine 2 biosynthetic: amino-acid amino-acid C4H07_RS04635 glu ilvA diaminopimeloyl- -L-tyrosine 3-phosphate semialdehyde 3-phosphate 3-phosphate an oxidized 1-(5-phospho- synthase: aroB ketol-acid asd acetylglutamate C4H07_RS00605 C4H07_RS17395 (2Z)-2-aminobut- 5-carboxylate acrylate reducing terminus) 3-phosphate phosphate cytochrome C4H07_RS08910 ilvA acetyltransferase acetyltransferase (indol-3-yl)acetate an L-arginyl- C4H07_RS02365 oxidoreductase: 3-methyl-2- oxopentanoate (S)-3-methyl-2- dehydrogenase: O c-type β kinase: argB D-alanine) 2 -D-ribosyl)-ATP reductoisomerase: L-aspartate 4- N-acetyl-L- Arg C4H07_RS05685 2-enoate 3-dehydroquinate (2Z)-2-aminobut- ArgJ: argJ ArgJ: argJ [tRNA ] formate acetyl-CoA oxobutanoate oxopentanoate tetrapeptide pruA cytochrome ilvC N-acetyl-L- Arg RS10875 a reduced L-aspartyl- phosphoribosyl- semialdehyde glu glutamate 5- a tRNA [+ 2 isozymes] (2R)-2,3- 2-enoate glutamate acetylornithine (R)-lactate N 2 -succinyl- 4-phosphate ATP N-acetyl-L- gln semialdehyde gln glu H O c-type type II 3- 4-hydroxy- 2 dihydroxy-3- glutamate transaminase: phosphate citrate synthase: (S)-malate L-glutamate-5- L-ornithine a sugar RS05425 a sugarcytochrome diphosphatase: dehydroquinate tetrahydrodipicolinate an L-glutamyl- isovaleryl-CoA aspartate- methylbutanoate carbamoyl- C4H07_RS01445 acetyltransferase: C4H07_RS11835 2-iminobutanoate semialdehyde C4H07_RS19495 dehydratase: aroQ Aromatic Compound imidazole Gln 2-methylbutanoyl-CoA semialdehyde dihydroxy-acid acetylglutamate synthase: phosphate aspartate [tRNA ] class II fumarate isobutanoyl-CoA isovaleryl-CoA 1-(5-phospho-β- Biosynthesis glycerol CO H C4H07_RS14775 undecaprenyl- a DNA containing 1-palmitoyl- a 3-(all-trans 1-arachidinoyl- 1-cis-vaccenoyl- an [amino group a 1-acyl-sn a 1-acyl-sn DNA combined dehydrogenase: dehydratase: 2-iminobutanoate kinase: argB C4H07_RS00855 cysteine-- 2 2 acetaldehyde hydratase: fumC trifunctional a cis,cis-delta17,35- a 2,3,4-saturated a 2,3,4-saturated 2- 3-(all-trans-heptaprenyl) (R)-3- 3-dehydroshikimate synthase bifunctional aminotransferase cys phosphate Asp-tRNA(Asn) dehydrogenase: N 2 -succinyl- a malonyl-[acp] a palmitoleoyl-[acp] sn-glycerol an alkylated DNA succinyl-CoA a 3-oxo acid 2-hydroxyhexadecanal -polyprenyl) 4-acetamidobutanal sn-glycerol sn-glycerol- -glycerol 3- asd D-ribosyl)-AMP tRNA ligase: citrate transcriptional diphospho-N- an apurinic/ benzene-1,2-diol hydroxybutanoate carrier protein]- -glycerol 3- with exogenous XTP a sugar RS00630 a sugar ilvD 4-hydroxy- large glutamate N- family protein: 4-hydroxyphenylpyruvate /Glu-tRNA(Gln) C4H07_RS11750 C54:2-[acp] fatty acyl-[acp] lysophosphatidate aldehyde N-acetylglutamyl- synthase: regulator/proline L-glutamate 5- acetylmuramoyl- UDP-N-acetyl- ketoacyl-ACP apyrimidinic site 1-acyl-sn-glycerol- 1-acyl-sn-glycerol-3-phosphate DNA-3- bifunctional 2- 3-oxoacid CoA- benzene-1,2-diolbifunctional 2- aldehyde 3-hydroxybutyrate 3-phosphate 3-phosphate C-terminal-γ- phosphate phosphate DNA to form a phosphoribosyl- shikimate tetrahydrodipicolinate subunit: carB C4H07_RS17230 C4H07_RS08885 an L-cysteinyl- amidotransferase: acetyl phosphate S-(hydroxymethyl) fumarate bifunctional DNA- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- RdgB/HAM1 family L-aspartate 4- dihydroxy-acid phosphate acetyltransferase/ biosynthesis hisH hisF bifunctional 2- 3-methylcrotonyl- semialdehyde L-alanyl-γ-D- α-D-glucosamine methyladenine polyprenyl-6- transferase dehydrogenase: dehydrogenase: dehydrogenase: (L-ornithyl) recombinational AMP dehydrogenase: Cys glutathione (E)-2- 2-oxobutanoate dehydrogenase/L- synthase III: 3-phosphate 3-phosphate polyprenyl-6- 3-phosphate 3-phosphate acetylornithine 3-phosphate 3-phosphate Holliday semialdehyde dehydratase: synthase: amino-acid [tRNA ] gatC gatA gatB methylcitrate CoA undecaprenyldiphospho- formamidopyrimidine C4H07_RS10955 C4H07_RS10955 C4H07_RS07410 non-canonical a metal a metal carbamoyl Cys [+ 7 isozymes] methylacrylyl-CoA glutamyl-L-lysyl- C4H07_RS12260 glycosylase: hydroxyphenol subunit A: hydroxyphenol -L-glutamate junction cyclohydrolase: aroE N-acetyl-gamma- C4H07_RS07840 L-ornithine a tRNA a 5-phosphooxy- acetate kinase: dehydrogenase/ methylcrotonoyl-CoA glutamate gamma- glycosylase/ acyltransferase: acyltransferase: acyltransferase: acyltransferase: transaminase: acyltransferase: acyltransferase: junction purine NTP a reduced ilvD phosphate acetyltransferase tyr pyruvate dehydratase/ muramoylpentapeptide beta-N- C4H07_RS11765 methylase/3- C4H07_RS18820 cation cation homoserine hisI 2-oxobutanoate glutamyl-phosphate (2S,4S)-4- L-glutamyl- C4H07_RS14780 class III alcohol acetyl/propionyl/ semialdehyde D-alanyl-D-alanine ditrans,octacis- beta-ketoacyl- C4H07_RS00195 C4H07_RS00195 aldehyde methylase/3- aldehyde SDR family C4H07_RS00195 C4H07_RS00195 C4H07_RS01445 C4H07_RS00195 C4H07_RS00195 resolvase H O c-type RS07275 ArgJ: argJ ammonium fermentation aconitate hydratase: enoyl-CoA enoyl-CoA acetylglucosaminyltransferase: DNA-(apurinic pyrophosphatase: 2 dehydrogenase: β shikimate 3-methyl-2- N-acetyl-L- aspartate/ Gln 2 demethylubiquinol 3- dehydrogenase dehydrogenase oxidoreductase: 1-(5-phospho- -D-ribosyl)- reductase: hydroxy-2,3,4,5- [tRNA ] dehydrogenase: methylcrotonyl- dehydrogenase: N - undecaprenyldiphospho- [acyl-carrier- or apyrimidinic 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- DNA-3- 3-oxoacid CoA- demethylubiquinol 3- RuvX: ruvX RS10870 cytochrome oxobutanoate to (S)-lactate C4H07_RS11895 succinate hydratase/ hydratase/ murG 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- aspartate 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- resolution of rdgB an oxidized acetate acetate C4H07_RS05665 5-[(5-phosphoribosylamino) acetolactate C4H07_RS04635 tetrahydrodipicolinate ornithine tyrosine/aromatic acetate C4H07_RS19380 CoA carboxylase putA β 3-phosphate 3-phosphate methyladenine O-methyltransferase transferase family protein: O-methyltransferase family protein: C4H07_RS18715 shikimate kinase: superpathway of L- isomerase isomerase succinylglutamate N-acetyl-(N-acetyl- -D- protein] site) lyase: mutM 3-phosphate 3-phosphate aminotransferase 3-phosphate 3-phosphate recombinational[+ 2 isozymes] XMP O c-type methylideneamino]imidazole- synthase N-acetyl-L- 4-hydroxy- aminotransferase: Asp-tRNA(Asn) pyruvate [+ 3 isozymes] subunit alpha: propanoyl-CoA UDP glycosylase 2 UbiG: ubiG subunit A: C4H07_RS18065 UbiG: ubiG C4H07_RS18065 acetoacetate 2 predicted L-homoserine glutamine-- family protein: L-glutamate succinylglutamate glucosaminyl)muramoyl- synthase II: fabF endonuclease acyltransferase: acyltransferase: 2-methoxy-6-(all-trans a 2-methoxy- acyltransferase: acyltransferase: an [amino groupfamily protein: acyltransferase: acyltransferase: junction cytochromea reduced C4H07_RS01015 2-isopropylmalate branched-chain large subunit: glutamate 5- tetrahydrodipicolinate threonine biosynthesis C4H07_RS05255 gln Ldh family ethanol family protein: C4H07_RS01455 a cis,cis-delta19,37- family protein: C4H07_RS10385 4-carboxamide tRNA ligase: /Glu-tRNA(Gln) cis-aconitate C4H07_RS02285 gamma- desuccinylase: L-alanyl-γ-D-glutamyl-L- acyl-carrier protein C4H07_RS18255 C4H07_RS18255 2-hydroxyhexadecanoate 6-(all-trans- 4-acetamidobutanoate C4H07_RS18255 C4H07_RS18255 C4H07_RS17230 C4H07_RS18255 C4H07_RS18255 formation of two H O c-type ABC synthase: amino acid C4H07_RS07655 semialdehyde oxidoreductase: C4H07_RS02285 III: nth a 2,3,4-saturated 1-palmitoyl-2- -heptaprenyl)phenol a 2,3,4-saturated a 1-arachidonoyl- 1,2-dicis- carrier protein]- a 1-acyl-2- a 1-acyl-2- 2 gln gln 1-(5-phosphoribosyl) reductase: dapB ornithine aspartate/ amidotransferase: methylcrotonoyl- semialdehyde C4H07_RS12170 lysyl-D-alanyl-D-alanine 3-oxo-C56:2-[acp] a 5'-phospho- a 3'-terminal C4H07_RS08890 succinate polyprenyl)phenol intact strands cytochrome transporter shikimate 3-phosphate C4H07_RS18425 oxaloacetate C4H07_RS03180 an L-glutaminyl- C4H07_RS17970 [+ 7 isozymes] [+ 7 isozymes] 1,2-diacyl-sn palmitoleoyl- a DNA containing 3-oxoacyl-CoA 2-acyl-sn-glycerol vaccenoyl- C-terminal-γ- arachidonoyl- palmitoyl-sn RS10880 an oxidized homoserine kinase: -5-((5- transaminase: [+ 8 isozymes] acetylornithine (S)-2,3,4,5- carbamoyltransferase: tyrosine/aromatic gatC gatA gatB bifunctional 2- CoA carboxylase: [DNA] unsaturated sugar acyl-carrier protein acyl-carrier protein an alkylated of L-glutamine aspartate/ [tRNA Gln ] (S)-lactate dehydrogenase: succinylglutamate -glycerol 3- sn-glycerol an apurinic/ 3-phosphate phosphatidate (L-glutamate 5- sn-glycerol -glycerol 3- O c-type C4H07_RS14360 2-isopropylmalate C4H07_RS16665 transaminase: (2S,3S)-3-hydroxy-2- 2 phosphoribosylamino) (S)-2-aceto-2- tetrahydrodipicolinate argF aminotransferase: Gln methylcitrate (S)-3-hydroxy- C4H07_RS01460 nucleobase 3-phosphoshikimate 1- tyrosine/aromatic a tRNA propanoyl pruA desuccinylase: phosphate 3-phosphate apyrimidinic site semialdehyde-2- 3-phosphate phosphate a metal a metalcytochrome methylideneamino) synthase: leuA branched-chain hydroxybutanoate C4H07_RS01445 3-(4- C4H07_RS10425 dehydratase/ isobutanoyl-CoA methylbutanoyl-CoA RS08435 gln RS08615 gln O-phospho- carboxyvinyltransferase: 2,3,4,5- aminotransferase: an L-glutaminyl- 3-methylglutaconyl- phosphate C4H07_RS13930 yl)-L-glutamate cation cation imidazole-4- amino acid aspartate hydroxyphenyl) Gln L-homoserine aroA ketol-acid tetrahydropyridine- C4H07_RS05255 [tRNA ] aconitate hydratase: CoA glu (2S)-2- acetate kinase: carboxamide isomerase: aminotransferase: reductoisomerase: aminotransferase 2,6-dicarboxylate N- pyruvate C4H07_RS11895 5-enolpyruvoyl- [+ 2 isozymes] glu 6 α α threonine C4H07_RS19480 isopropylmalate C4H07_RS17395 ilvC family protein: Pentose Phosphate Pathways C4H07_RS14780 a nascent peptidoglycan a ring-opened 7- an O - 1-cis-vaccenoyl- 1-stearoyl- a [glutamine 3-methoxy-4- 3-(all-trans (24E)-3 ,7 - a 2-methyl an odd numbered a [protein]-L- 1-palmitoyl- succinyltransferase: [+ 3 isozymes] (S)-3-hydroxy- a [protein]- an N-modified β 4-tyrosol an aromatic prop-2-ynal a metal a metal synthase: shikimate 3-phosphate 3-isopropylmalate C4H07_RS17230 asp glutamate-- 2-methylacetoacetyl-CoA (meso-DAP containing) methylguanine in DNA methylguanine a palmitoleoyl-[acp] sn-glycerol- a palmitoyl-[acp] sn-glycerol synthetase]-O hydroxyphenylglycolaldehyde a hexanoyl-[acp] -decaprenyl) dihydroxy-5 - branched straight chain β sn-glycerol RS08445 predicted phosphoribulosylformimino- (R)-2,3-dihydroxy- dapD glu L-cysteine aminoacyl-[tRNA] -isoaspartate amino acid ITP cation cation C4H07_RS05670 L-citrulline tRNA ligase: isobutanoate propanoate lytic transglycosylase bifunctional DNA- in DNA 3-phosphate 3-phosphate 4 -(5'-adenylyl) aldehyde benzene-1,2-diol cholest-24-enoyl-CoA 2,3,4-saturated protein-L- 3-phosphate aldehyde ABC efflux chorismate dehydratase 3-methylpentanoate N-acetyl-L- pentose phosphate pathway D-threo-isocitrate methylated-DNA-- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- aminoacyl-tRNA beta-ketoacyl-[acyl- bifunctional 2- 3-alpha,7- S-(hydroxymethyl) 2,3,4-saturated 1-acyl-sn-glycerol- AICAR-phosphate N-succinyl-2-amino- 3-hydroxyisobutyrate HMG-CoA acetyl-CoA C- domain-containing dehydrogenase: aldehyde isoaspartate(D- aspartate/ dehydrogenase: RdgB/HAM1 family thiol transporter thiol synthase: small subunit: leuD val aspartate kinase: C4H07_RS04545 an L-glutamyl- (non-oxidative branch) L-tyrosine degradation I formamidopyrimidine 3-phosphate 3-phosphate -L-tyrosine bifunctional [glutamate- hydrolase: carrier-protein] polyprenyl-6- glutathione fatty aldehydealdehyde fatty aldehyde thr dihydroxy-acid ornithine 6-ketopimelate NADH repair acyltransferase: [protein]-cysteine S- alpha, 12-alpha- 3-phosphate tyrosine/aromatic non-canonical aroC argininosuccinate C4H07_RS08910 [tRNA Glu ] NADP-dependent dehydrogenase: protein: glycosylase/ acyltransferase: -ammonia ligase]- C4H07_RS10955 synthase II: fabF dehydrogenase/ dehydrogenase dehydrogenase aspartate) O- C4H07_RS10955 of a thiol 3-isopropylmalate dehydratase: hydrogencarbonate D-ribulose hydroxymethylglutaryl- C4H07_RS01465 L-glutamate methyltransferase: acyltransferase: C4H07_RS03700 hydroxyphenol trihydroxy-5-beta- acyltransferase: aminotransferase: purine NTP a metal a metal imidazole acetylornithine alanine synthase: argG a tRNA glu isocitrate mmsB C4H07_RS03970 DNA-(apurinic C4H07_RS00195 adenylyl-L-tyrosine aldehyde class III alcohol family protein: family protein: methyltransferase: aldehyde RS08460 group threonine dehydratase: ilvD 5-phosphate CoA lyase: degradation X C4H07_RS17915 C4H07_RS00195 aminoacyl-tRNA ketoacyl-ACP methylase/3- cholest-24-enoyl- C4H07_RS00195 C4H07_RS10425 pyrophosphatase: cation cation glycerol chorismate deacetylase: carbamoyl- transaminase: L-aspartyl- dehydrogenase: NADH (S)-methylmalonate- [+ 3 isozymes] tyr [+ 2 isozymes] or apyrimidinic phosphorylase/ dehydrogenase dehydrogenase: C4H07_RS18065 C4H07_RS18065 C4H07_RS10030 dehydrogenase ammonia-lyase: leuD leuC L-arginino- C4H07_RS19865 a mature peptidoglycan 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- hydrolase: synthase III: demethylubiquinol 3- CoA hydratase: 1-acyl-sn-glycerol- rdgB Peptide RS09170 Peptide phosphate dihydroxy-acid argE C4H07_RS05660 4-phosphate C4H07_RS07220 semialdehyde site) lyase: mutM methylated-DNA-- [glutamate-- C4H07_RS19380 aspartate/ phosphate succinate [+ 2 isozymes] propanoyl-CoA acetyl-CoA aspartate/tyrosine/ γ a nascent peptidoglycan 3-phosphate C4H07_RS06310 family protein: C4H07_RS12260 O-methyltransferase α C4H07_RS03305α aldehyde aldehyde protein-L- family protein: C4H07_RS15400 synthase: dehydratase: ribulose-phosphate ribose-5- glu with (L-alanyl- -D-glutamyl- 2,6-diamino-4- [protein]-cysteine S- 3-phosphate (24R,25R)-3 ,7 ,24- (4-hydroxyphenyl) 3-phosphate tyrosine/aromatic IMP prephenate 2-isopropylmaleate acetylornithine synthase N-succinyl-L,L-2,6- aromatic aminotransferase: (meso-DAP containing) an apurinic site ammonia-ligase] an N-modified an uncharged C4H07_RS18065 UbiG: ubiG β dehydrogenase: isoaspartate O- C4H07_RS18065 a metal a metal aminodeoxychorismate/ ilvD aspartate- 3-epimerase: phosphate 2-oxoglutarate meso-2,6-diaminopimeloyl- hydroxy-5-(N-methyl) methyltransferase: acyltransferase: acyltransferase: a 3-oxooctanoyl-[acp] 6-(all-trans- trihydroxy-5 - acetaldehyde dehydrogenase: acyltransferase: aminotransferase: RS18030 threonine hisH hisF deacetylase: large diaminopimelate argininosuccinate acetoacetate C4H07_RS05255 Glu/Leu/Phe/Val with GlcNAc terminus within DNA adenylyltransferase: amino acid tRNA a 2-methyl an odd numberedC4H07_RS10955 methyltransferase: anthranilate synthase: dehydratase: 3-isopropylmalate semialdehyde isoleucine- C4H07_RS02980 D-alanine) tetrapeptide formamidopyrimidine C4H07_RS18170 C4H07_RS18255 C4H07_RS18255 vanillyl mandelate decaprenyl)-2- cholestanoyl CoA C4H07_RS10955 C4H07_RS18255 propynoate cation cation ammonia- (S)-3-methyl-2- argE subunit: carB lyase: argH ile isomerase dehydrogenase: 1-cis-vaccenoyl- 1-stearoyl- glnE straight chain 1-palmitoyl- C4H07_RS05255 lipid A RS11655 lipid A C4H07_RS02990 pheA succinyl- -tRNA aspartate/tyrosine/ a [protein]-S- a [glutamine- branched 2,3,4- βC4H07_RS01305 an aromatic lyase, D-erythro-1- dehydratase oxopentanoate dehydrogenase: RpiA: rpiA (R)-NADHX C4H07_RS08635 a guanine in DNA 2-palmitoleoyl- 2-palmitoyl- methoxy-phenol 2,3,4-saturated a protein L- - 2-myristoyl AICAR C4H07_RS02995 diaminopimelate ligase: ileS aromatic aminotransferase: methyl-L-cysteine acyl-carrier protein acyl-carrier protein ADP synthetase]- saturated fatty acid 2-oxo-acid biosynthetic: (imidazol-4- small subunit: leuD L-ornithine carbamoyl arg asd an L-isoleucyl- D-xylulose (S)-3-amino-2- hydrogencarbonate 2-oxoglutarate sn-glycerol- sn-glycerol fatty acid isoaspartate phosphatidate branched-chain desuccinylase: Ile NAD(P)H-hydrate L-tryptophan degradation to L-histidine C4H07_RS10425 L-tyrosine ilvA yl)-glycerol prephenate 3-isopropylmalate phosphate L-aspartate 4- [tRNA ] 5-phosphate D-ribose 5- methylpropanoate 3-phosphate 3-phosphate α-methyl ester potassium- amino acid dapE a tRNA Ile epimerase: 2-amino-3-carboxymuconate degradation II 3-(4-hydroxyphenyl)pyruvate + + fluoride RS13715 fluoride 3-phosphate anthranilate dehydratase: semialdehyde phosphate K transporting K (2Z)-2-aminobut- transaminase: (S)-NADHX C4H07_RS06155 semialdehyde imidazoleglycerol- leuD leuC ornithine Respiration ATPase 2-enoate prephenate prephenate C4H07_RS16665 L,L-diaminopimelate homoserine 4-hydroxyphenylpyruvate an O 4 - a peptidoglycan 1-stearoyl- 2-methoxy-6-all 4-methyl-3- N-acetyl-α- imidazole (24R,25R)- a 1-alkyl-sn 1-palmitoyl- (E)-4-hydroxy-3- phosphate transketolase: tkt his 6 37 a sulfurated a single a [protein]- an acyl-[acyl- a 3- anthranilate (2R,3S)-3- carbamoyltransferase: dehydrogenase: trp dioxygenase: hppD N -dimethylallyladenosine methylthymine sn-glycerol 3,4-dihydroxyphenylglycolaldehyde trans-heptaprenyl- succinyl-CoA D-muramoyl- methionol 3α,7α,12α,24- -glycerol 3- sn-glycerol methylbut-2-en- decanal dehydratase dehydratase: dehydrogenase/ branched-chain L-phenylalanine stranded DNA L-cysteine dimer with oxoadipate demethyubiquinol felinine acetaldehyde dGDP phosphoribosyltransferase: trpD argF L-citrulline biosynthesis 2-oxoglutarate decarboxylation to succinyl-CoA tryptophan 2,3- in tRNA [sulfur carrier] carrier protein] + + chloride RS05785 chloride C4H07_RS11640 arogenate isopropylmalate diaminopimelate C4H07_RS05665 degradation II (anaerobic) exodeoxyribonuclease in DNA pentapeptide 3-phosphate aldehyde 1,4-benzoquinol CoA transferase L-alanine(1-) bifunctional 2- S-(hydroxymethyl) aldehyde tetrahydroxy-5β- phosphate 3-phosphate 1-yl diphosphate aldehyde K RS07255 K HisB: hisB amino acid leucine-- D-sedoheptulose D-glyceraldehyde homogentisate succinate methylated-DNA-- 1-acyl-sn-glycerol- bifunctional N-acetylmuramoyl- cystathionine 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- flavodoxin- ribonucleotide- N-(5-phosphoribosyl) 3-isopropylmalate leu dioxygenase: VII small subunit: dehydrogenase: subunit B: polyprenyl-6- glutathione dehydrogenase: cholestanoyl 3-alpha,7-CoA dehydrogenase 3-(imidazol-4- prephenate dehydrogenase aminotransferase: epimerase: dapF tRNA ligase: 7-phosphate 3-phosphate a [2-oxoglutarate dehydrogenase, [protein]-cysteine S- stems (meso- 3-phosphate demethylmenaquinone L-alanine amidase: beta-lyase: 3-phosphate 3-phosphate dependent -anthranilate dehydrogenase: L-homoserine NADH kynA urocanate C4H07_RS05585 N-acetylmuramoyl- C4H07_RS10955 C4H07_RS10390 C4H07_RS10955 alpha, 12-alpha- family protein: diphosphate 2-iminobutanoate yl)-2-oxopropyl dehydratase: family protein: C4H07_RS17395 asp L-citrulline dehydrogenase N-Formyl-L- homogentisate hydrophobic methyltransferase: diaminopimelate acyltransferase: methyltransferase/2- C4H07_RS12290 hydroxyphenol metC dehydrogenase/ acyltransferase: acyltransferase: (E)-4-hydroxy- gln C4H07_RS11555 an L-leucyl- phe trihydroxy-5-beta- reductase: phosphate phosphoribosylanthranilate C4H07_RS15065 leuB 6 alpha- kynurenine exodeoxyribonuclease containing)L-alanine amidase: aldehyde 3-oxoacid CoA- methylase/3- class III alcohol aldehyde C4H07_RS18065 2+ 2+ pheA meso-diaminopimelate Leu transaldolase: tal E2 protein] N 1,2-dioxygenase: membrane anchor C4H07_RS17915 C4H07_RS18255 methoxy-6-polyprenyl- N-acetylmuramoyl- C4H07_RS18255 C4H07_RS00195 3-methylbut- an anion RS17965 an anion Ca RS16610 Ca homoserine kinase: [tRNA ] aminotransferase C4H07_RS12290 cystathionine cholest-24-enoyl- C4H07_RS04510 histidinol- isomerase: C4H07_RS12320 (2S)-2-isopropyl- ile ketoglutarate 6 VII large subunit: dehydrogenase transferase: demethylubiquinol 3- dehydrogenase: dehydrogenase aldehyde imidazole Leu -lipoyl-L-lysine arylformamidase: C4H07_RS03640 protein: sdhD 2-methylsulfanyl-N - methylated-DNA-- 1-acyl-sn-glycerol- 1,4-benzoquinol L-alanine amidase: beta-lyase: 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 2-enyl- C4H07_RS04515 C4H07_RS14360 a tRNA class I/II-fold O-methyltransferase C4H07_RS19380 CoA hydratase: phosphate 3-(4-hydroxyphenyl) 3-oxosuccinate argininosuccinate dehydrogenase: an unsulfurated 37 C4H07_RS05775 N-acetylmuramoyl- family protein: methylase UbiE: ubiE C4H07_RS18820 family protein: diphosphate dehydrogenase: 1-(2- 3-phenyl-2- diaminopimelate glycerol D-erythrose pyridoxal kynB met 5'-deoxyadenosine dimethylallyladenosine [protein]-cysteine S- a peptidoglycan 3-phosphate 6-methoxy-3-methyl-2- C4H07_RS18630 metC (24E)-3α,7α,12α- 3-phosphate 3-phosphate transaminase: pyruvate synthase: argG F6P mdeB 4-imidazolone- 4-maleyl-acetoacetate [sulfur carrier] a single-stranded a ribonucleoside L-alanine amidase: C4H07_RS18065 C4H07_RS18825 N-acetyl-D- UbiG: ubiG 3-methyl-3- 3-(methylsulfanyl) C4H07_RS18065 C4H07_RS03305 C4H07_RS10955 GDP carboxyphenylamino) oxopropanoate decarboxylase: lysA phosphate O-phospho- 4-phosphate in tRNA methyltransferase: γ acyltransferase: all-trans-heptaprenyl- ala trihydroxy- acyltransferase: acyltransferase: 2-C-methyl-D-synthase: ispG 2-oxobutanoate phosphate- 5-propanoate oligodeoxyribonucleotide 5'-monophosphate L-alanyl- -D- C4H07_RS18630dimer with 4-methyl-3- muramate pyruvate propanal an anion RS09405 an anion predicted C4H07_RS10745 -1-deoxy-D-ribulose aminotransferase aspartate/ synthase: 2-oxoglutarate L-kynurenine C4H07_RS18170 C4H07_RS00195 3,4-dihydroxymandelate 1,4-benzoquinol succinate UQH sulfanylbutan-1-ol 4-imidazoleacetate 5β-cholest- erythritol-2,4- decanoate L-homoserine dependent enzyme: glutamyl-meso-2,6- pentapeptide a 1-stearoyl 2- oxoadipyl-CoA 2 a 2-acyl-1-alkyl-C4H07_RS00195 1-palmitoyl-2-C4H07_RS18255 ABC L-arginino- transketolase: tkt dehydrogenase maleylacetoacetate a [protein]-S- ectoine ectoine acetolactate histidinol- 5-phosphate class I/II-fold tyrosine/aromatic lys pro hisH hisF C4H07_RS13885 a thymine in DNA stem (meso- acyl-carrier protein acyl-sn-glycerol 24-enoyl-CoA sn-glycerol cis-vaccenoyl cyclodiphosphate transporter 4-methyl-2- succinate threonine 2-oxoglutarate isomerase: maiA methyl-L-cysteine diaminopimeloyl- synthase phosphate indole-3- pyridoxal aminotransferase: L-arginine L-proline biosynthesis [+ 7 isozymes] val E1 component: diaminopimelate 3-phosphate 3-phosphate phosphatidate of ectoine oxopentanoate synthase: valine--tRNA ligase: D-glyceraldehyde dehydrogenase 3-phenyl-2-[+ 2 isozymes] D-alanyl-D-alanine Mg 2+ Mg 2+ large subunit: transaminase: glycerol phosphate- C4H07_RS05255 degradation I I (from L-glutamate) argininosuccinate C4H07_RS14155 RS02975 E1 component: N-formimino- 4-fumaryl-acetoacetate containing) 2+ 2+ phosphate branched-chain trifunctional C4H07_RS05670 C4H07_RS10700 an L-valyl- 3-phosphate oxopropanoate Co Co C4H07_RS07655 C4H07_RS19465 dependent enzyme: aspartate/ (arginase pathway) lyase: argH glu C4H07_RS14155 a [2-oxoglutarate Fe 3+ RS08015 Fe 3+ amino acid transcriptional [tRNA Val ] a [2-oxoglutarate L-glutamate [+ 8 isozymes] synthase C4H07_RS13885 tyrosine/aromatic glu L-ornithine thr dehydrogenase 3-hydroxy- fumarylacetoacetate L-histidinol transaminase: regulator/proline a tRNA Val dehydrogenase[+ 5 isozymes] N-acetyl-D-glucosaminyl-N- GlcNAc-1,6- 1-myristoyl- 2-methoxy-6-all 3-oxo-2-(cis- a 3-oxooctadecanoyl- 1-palmitoyl- 1-oleoyl-sn TrpC: trpC arg arg biosynthesis II E2 protein] N 6 -S- L-kynurenine hydrolase: C4H07_RS15970 cob(II)alamin- S-(4-hydroxy- S-(4-hydroxy- D-glyceraldehyde phosphate [+ 2 isozymes] aminotransferase: glutamate 5-kinase: glutamate 5-kinase: 6 a cis,cis-delta13,31- 3-dimethylsulfoniopropionaldehyde benzaldehyde dodecanal 2+ 2+ (S)-2-aceto-2- C4H07_RS16665 arginase: dehydrogenase/L- E2 protein] N - methylmalonyl- acetylmuramoyl-L-alanyl-D-glutamyl- a malonyl-[acp] anhMurNAc- a myristoyl-[acp] sn-glycerol trans-nonaprenyl- 2'-pentenyl)- 2-methylpentan- L-djenkolate 3-methylbutan- [acp domain within a dodecanoyl-[acp] 3-phosphate sn-glycerol -glycerol 3- Co Co (1S,2R)-1-C-(indol-3- C4H07_RS10425 C4H07_RS15990 succinyldihydrolipoyl- fumarylacetoacetase: fahA ATP [CblC-CblD C50:2-[acp] dADP RS09160 hydroxybutanoate C4H07_RS07635 C4H07_RS15990 glutamate gamma- dihydrolipoyl-L-lysine kynureninase: CoA mutase 6-carboxy-L-lysyl-D-alanine L-Ala-γ-D-Glu- 3-phosphate aldehyde 1,4-benzoquinol cyclopentane-1- a fatty acid synthase] aldehyde 3-phosphate phosphate aldehyde aldehyde Mg 2+ Mg 2+ 2+ 2+ branched-chain γ L-asparagine biosynthesis phenylacetaldehyde ketoacyl-ACP 1-acyl-sn-glycerol- 2-yl)-L-cysteine cystathionine 2-yl)-L-cysteine enoyl-ACP Mo RS03935 Mo yl)glycerol 3-phosphate phe -L-glutamyl 2-oxoglutarate L-lysine complex] muramoyltetrapeptide bifunctional cystathionine cystathionine acyl-CoA 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- ribonucleotide- ketol-acid arginase: rocF semialdehyde γ kynU fumarate acetoacetate cob(I)yrinic acid DAP-D-AlaN-acetylmuramoyl- dehydrogenase: (3-oxohexanoyl) dehydrogenase: dehydrogenase dehydrogenase amino acid 5-phosphate Glu/Leu/Phe/Val -L-glutamyl III (tRNA-dependent) N-formyl- carboxypeptidase: synthase III: 3-phosphate demethylmenaquinone acetyl-CoA C- beta-lyase: beta-lyase: beta-lyase: reductase 3-phosphate 3-phosphate reductoisomerase: tyr dehydrogenase: a,c-diamide L-alanine amidase: C4H07_RS10955 -CoA synthetase: family protein: family protein: diphosphate tryptophan aminotransferase: L-ornithine dehydrogenase: 5-phosphate alanine- glyoxylate cycle aldehyde L-glutamate C4H07_RS08485 C4H07_RS12260 acyltransferase: methyltransferase/2- metC metC metC FabI: fabI C4H07_RS10955 acyltransferase: glutamate-5- putA 3-hydroxyanthranilate C4H07_RS12290 acyltransferase: C4H07_RS02235 acyltransferase: reductase: ilvC histidinol synthase: trpB C4H07_RS17395 C4H07_RS08635 -tRNA dehydrogenase L-arginine adenosyltransferase: C4H07_RS00195 aldehyde C4H07_RS18065 C4H07_RS18065 Mg 2+ RS05555 Mg 2+ asp ala LD-carboxypeptidase: beta-ketoacyl- methoxy-6-polyprenyl- C4H07_RS01465 cystathionine cystathionine cystathionine a (3R)-3- enoyl-ACP aldehyde C4H07_RS00195 C4H07_RS00195 C4H07_RS04510 (R)-2,3-dihydroxy- C4H07_RS17490 ornithine--oxo-acid semialdehyde ligase: family protein: N-formylglutamate a [cobalamin C4H07_RS04120 adenosylcobalamin- N-acetylmuramoyl- 3-oxo-2-(cis- predicted glu (S)-1-pyrroline- glutamate-5- acetyl-CoA degradation VI a [cyanocobalamin C4H07_RS13975 [acyl-carrier- 1-acyl-sn-glycerol- dehydrogenase 1,4-benzoquinol beta-lyase: beta-lyase: beta-lyase: hydroxyoctadecanoyl- reductase FabI: dehydrogenase aldehyde aldehyde histidinol transaminase: dehydrogenase: succinate 2-oxoglutarate Macromolecule Modification deformylase: hutG trafficking triphosphate [methylmalonyl- N-acetyl-D-glucosaminyl-N- L-alanine amidase: [+ 3 isozymes] 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- C4H07_RS04515 ABC 3-methylpentanoate leu 5-carboxylate semialdehyde alaS an L-alanyl- C4H07_RS18065 (arginase 2 pathway) family protein: methylase UbiE: ubiE 2'-pentenyl)- metC [acp domain within C4H07_RS03235 family protein: dehydrogenase: dehydrogenase: taurine taurine dehydrogenase: C4H07_RS01790 C4H07_RS11570 dehydrogenase reductase CblC] D-ala acetylmuramoyl-L-alanyl-D- protein] L-alanyl-γ-D- N-acetyl-β-D- 3-phosphate 6-methoxy-3-methyl-2- acetyl-CoA metC metC 3-phosphate 3-phosphate transporter ser indole Ala aldehyde protein CblD] CoA mutase] C4H07_RS18630 C4H07_RS18065 cyclopentane- 4-methyl-4- S-(sulfanylmethyl) 2-methyl-3- a (2E)-dodec- C4H07_RS18065 C4H07_RS10955 C4H07_RS10955 ADP dihydroxy-acid superpathway of L-serine glutamate 5-kinase: dehydrogenase: [tRNA ] E1 component: glutamyl-6-carboxy-L-lysine synthase II: fabF acyltransferase: all-trans-nonaprenyl- pyruvate a fatty acid synthase] acyltransferase: hisD uracil degradation gln Ala 2-amino-3- arg glutamyl-meso-2,6- glucosamine-1,6- pyruvate pyruvate acyltransferase: predicted of taurine dehydratase: L-glutamate-5- L-glutamate-5- C4H07_RS11570 a tRNA protein S-nitrosylation dehydrogenase: glu a cis,cis-delta15,33- DMSP 1-butanoyl-CoA sulfanylpentan-2-ol -L-cysteine sulfanylbutan-1-ol 2-enoyl-[acp] 3-phospho- benzoate laurate and glycine biosynthesis I I (reductive) C4H07_RS15990 glyoxylate C4H07_RS14155 carboxymuconate- arginase: acyl-carrier protein diaminopimeloyl- anhydro-N-acetyl- C4H07_RS182551,2-dimyristoyl- 1,4-benzoquinol a 1-palmitoyl-2-C4H07_RS18255 C4H07_RS18255 ABC ilvD histidinal tryptophan semialdehyde semialdehyde an L-aspartyl- and denitrosylation C4H07_RS10955 3-oxo-C52:2-[acp] D-glycerate dioleoyl sulfate sulfate [+ 2 isozymes] 6-semialdehyde glycine cleavage C4H07_RS07635 D-alanine β-D-muramate acyl-carrier protein sn-glycerol acyl-sn-glycerol transporter biotin RS02485 biotin synthase: trpB uracil γ-L-glutamyl arg imidazole [tRNA Asn ] phosphatidate dihydroxy-acid 3-phospho-D-glycerate trifunctional L-glutamate-5- malate synthase G: a [protein]- phenylacetate 3-phosphate 3-phosphate of sulfate histidinol C4H07_RS17490 5-phosphate glycerol isocitrate lyase: aceA a [glycine-cleavage arginase: rocF dehydratase: phosphoglycerate L-proline biosynthesis transcriptional semialdehyde Asp-tRNA(Asn) C4H07_RS00890 L-cysteine dehydrogenase: phosphate complex H protein] L-ornithine ilvD dehydrogenase: serA III (from L-ornithine) glutamate-5- /Glu-tRNA(Gln) regulator/proline arginase: synthase: asn 6 sulfate RS05545 sulfate hisD trp (S)-1-pyrroline- semialdehyde N -lipoyl-L-lysine a (2R)-2-hydroxy 1-palmitoyl- a 2-methoxy-6-all- 3-oxo-2-(cis-2'-pentenyl) (S)-3- a 3-oxohexanoyl- (indol-3-yl) 1-myristoyl- biotin RS17375 biotin (S)-3-methyl-2- 3-phosphooxypyruvate 5,6-dihydrouracil dehydrogenase/L- amidotransferase: L-citrulline degradation ornithine--oxo-acid cob(II)alamin- an apo-["base- 16-hydroxypalmitate a cis,cis-delta15,33- 3,4-dihydroxyphenylacetaldehyde a uracil in DNA (S)-mandelate glycolaldehyde an aldehyde 1-octanal 5-carboxylate ornithine--oxo-acid C4H07_RS07635 hisH hisF glycine glycine a malonyl-[acp] even numbered a palmitoyl-[acp] sn-glycerol trans-polyprenyl- -cyclopentane-1-(3R- hydroxyhexadecanoyl- [acp domain within an arachidoyl-[acp] acetaldehyde sn-glycerol oxopentanoate L-ornithine glutamate gamma- dehydrogenase: gatC gatA gatB an L-asparaginyl- transaminase: ATP [CblC-CblD off/His-on" C52:2-[acp] ATP his hydantoinase/ pyrroline-5- transaminase: arginase: [+ 7 isozymes] a [protein] 3- cleavage cleavage long-chain fatty ketoacyl-ACP straight chain 3-phosphate aldehyde 1,4-benzoquinol uracil-DNA mandelate racemase: hydroxyhexanoyl)-CoA CoA a fatty acid synthase] enoyl-ACP aldehyde 3-phosphate aldehyde aldehyde aldehyde 3-phosphoserine/ ornithine--oxo-acid C4H07_RS11570 a 4-phosphooxy- [tRNA Asn ] L-arginine degradation C4H07_RS01790 complex] B12-enzyme] 1-acyl-sn-glycerol- bifunctional enoyl-CoA enoyl-CoA 1-acyl-sn-glycerol- branched-chain semialdehyde C4H07_RS01790 rocF nitrosothio- system cob(I)yrinic acid acid--CoA ligase: 2,3,4-saturated dehydrogenase: glycosylase: C4H07_RS13000 acyl-CoA dehydrogenase: dehydrogenase dehydrogenase: dehydrogenase bifunctional phosphohydroxythreonine oxoprolinase carboxylate L-aspartyl- tRNA Asn VII (arginase 3 pathway) L-citrulline system synthase III: long-chain fatty 3-phosphate demethylmenaquinone hydratase/ reductase 3-phosphate sulfate RS06565 sulfate amino acid transaminase: dehydrogenase: L-glutamate-5- ammonium L-alanine protein L-glutamate-5- hydratase/ synthetase: ala RS09520 ala family protein: reductase: Asn D-threo-isocitrate (S)-malate protein a,c-diamide C4H07_RS05530 C4H07_RS12260 fatty acid acyltransferase: C4H07_RS10955 C4H07_RS03950 mandelate racemase/ FabI: fabI C4H07_RS10955 family protein: C4H07_RS10955 family protein: adenylate transaminase: serC C4H07_RS01790 putA semialdehyde [tRNA ] ornithine acid--CoA ligase: methyltransferase/2- isomerase isomerase C4H07_RS02235 acyltransferase: transaminase: L-methionine biosynthesis III C4H07_RS15520 L-glutamate-5- GcvH: gcvH semialdehyde adenosyltransferase: [+ 6 isozymes] C4H07_RS18065 C4H07_RS18065 cyclase toxin/ C4H07_RS13380 arg carbamoyltransferase: GcvH: gcvH beta-ketoacyl- C4H07_RS15820a (R)-2-hydroxy C4H07_RS00195 aldehyde methoxy-6-polyprenyl- uracil-DNA muconate lactonizing family protein: family protein: a (3R)-3- enoyl-ACP aldehyde C4H07_RS00195 aldehyde C4H07_RS16665 semialdehyde L-glutamate ornithine--oxo-acid L-ornithine bifunctional 2- a [glycine-cleavage a [cobalamin C4H07_RS04120 a holo-["base- hemolysin O-phospho-L-serine hydantoinase/ Asp-tRNA(Asn) argF [+ 4 isozymes]a [glycine-cleavage a [cyanocobalamin 16-hydroxypalmitoyl- [acyl-carrier- [+ 6 isozymes] dehydrogenase 1,4-benzoquinol glycosylase: enzyme family protein: C4H07_RS02285 hydroxyhexanoyl- reductase FabI: dehydrogenase aldehyde dehydrogenase aldehyde a short a short methylcitrate Ldh family carbamoyl 6 AMP diphosphate even numbered 1-acyl-sn-glycerol- C4H07_RS02285 1-acyl-sn-glycerol- branched-chain gamma- pro transaminase: /Glu-tRNA(Gln) 6 complex H protein] N - trafficking triphosphate off/His-on" family protein: C4H07_RS17320 C4H07_RS14005 family protein: dehydrogenase: family protein: dehydrogenase: CyaA: cyaA L-homoserine oxoprolinase ornithine aspartate- dehydratase/ oxidoreductase: phosphate complex H protein] N reductase CblC] CoA protein] diphosphate AMP straight chain 3-phosphate a 6-methoxy-3-methyl-methylase UbiE: ubiE 3-oxo-2-(cis-2'-pentenyl)[+ 7 isozymes] [+ 7 isozymes] [acp domain within C4H07_RS03235 3-phosphate chain RS17595 chain amino acid semialdehyde C4H07_RS01790 amidotransferase: a [protein]- aminomethyldihydrolipoyl- protein CblD] B12-enzyme] C4H07_RS18065 an apyrimidinic (2E)- a (2E)-icos- C4H07_RS18065 C4H07_RS10955 C4H07_RS18065 C4H07_RS10955 cyclic-AMP homoserine O- phosphoserine family protein: carbamoyltransferase: -tRNA aconitate hydratase: C4H07_RS05685 S-nitrosoglutathione arginase: -dihydrolipoyl-L-lysine synthase II: fabF 2,3,4-saturated acyltransferase: 2-all-trans-polyprenyl- uracil (R)-mandelate -cyclopentane-1-(E- a fatty acid synthase] acyltransferase: fatty acid fatty acid aminotransferase: dehydrogenase: asp L-cysteine carbamoyl- L-lysine (S)-1-pyrroline- (3,4-dihydroxyphenyl) site in DNA 2-enoyl-[acp] phosphatase SerB: serB C4H07_RS15950 gatC gatA gatB C4H07_RS07635 a cis,cis-delta17,35- fatty acyl CoA C4H07_RS18255 1,4-benzoquinol hexadecenoyl-CoA (indol-3-yl)acetate glycolate a carboxylate octanoate C4H07_RS17395 acetyltransferase: (S)-1-pyrroline- pruA L-ornithine argF ligase: C4H07_RS11895 [+ 2 isozymes] 5-carboxylate acyl-carrier protein acetate hexa-2-enoyl)-CoA 1,2-dimyristoyl-C4H07_RS18255 S-(hydroxymethyl) arginase: rocF phosphate L-methionine degradation 3-oxo-C54:2-[acp] dipalmitoyl C4H07_RS00250 3-ureidopropanoate 5-carboxylate S-adenosyl-L-methionine cycle II aspS an L-aspartyl- [+ 3 isozymes] acyl-carrier protein sn-glycerol a short a short O-acetyl-L- L-citrulline glutathione synthase I (to L-homocysteine) pyrroline-5- phosphatidate hydrogen sulfide ser glu an L-asparaginyl- [tRNA asp ] 3-phosphate chain RS17740 chain ile homoserine pyrroline-5- Asn large carboxylate [tRNA ] tRNA asp cis-aconitate oxaloacetate dehydrogenase/ glycine carboxylate urea subunit: carB reductase: fatty acid fatty acid serine met S-adenosyl-L-methionine cycle I bifunctional 2- class III alcohol L-ornithine met cleavage L-tryptophan superpathway of L- hydroxymethyltransferase: reductase: methionine dehydrogenase: methionine degradation I C4H07_RS13380 1-palmitoyl- 6-methoxy-2-all- 2-bromo-3-(4- 3-oxo-2-(cis-2'-pentenyl) an acetoacetyl-[acp methylcitrate carbamate system a cis,cis-delta11,29- a 7,8-dihydro-8- a cis- an oxidized c- an L-cysteinyl- phytenal asparagine biosynthesis C4H07_RS13380 adenosyltransferase: ornithine a cis,cis-delta9,27-C46:2-[acp] a malonyl-[acp] 18-hydroxystearate a malonyl-[acp] sn-glycerol (S)-lactate trans-octaprenyl- glutathione nitrophenyl) DMKH2-11 -cyclopentane-1-(3R- 2-phenylethanol domain within a (2E)-hexadecenal β-alanine a fatty aldehyde methylglyoxal C4H07_RS04675 dehydratase/ C4H07_RS19380 adenosyltransferase: protein (via anthranilate) oxoguanine in DNA [tRNA Cys ] dIDP a short a short L-homocysteine β-alanine pro C48:2-[acp] vaccenoyl-[acp] 3-phosphate type cytochrome 1,4-benzoquinone hydroxybutanoyl)-CoA fatty acid synthase] aldehyde aldehyde aldehyde 5-methyltetrahydropteroyltriglutamate- C4H07_RS04025 SAM S-(hydroxysulfenamide) cyclodeaminase C4H07_RS04025 GcvH: gcvH ketoacyl-ACP synthase long-chain fatty ketoacyl-ACP bifunctional DNA- 1-acyl-sn-glycerol- alpha-hydroxy-acid bifunctional propanoateglutathione S- bifunctional enoyl-CoA S-(hydroxymethyl) aminoacyl-tRNA glyoxalase/ chain RS18805 chain ammonia tyrosine-- aconitate hydratase: acyl-CoA 4-aminobutyrate- nucleoside- asp gly pro - homocysteine S- L-cysteine glycine tyr family protein: SAM trp III: C4H07_RS12260 acid--CoA ligase: synthase III: formamidopyrimidine 3-phosphate oxidizing protein: transferase: demethylmenaquinone glutathione hydrolase: dehydrogenase: dehydrogenase bleomycin dehydrogenase fatty acid fatty acid C4H07_RS11895 citrate synthase: glutathione glycine cleavage system demethylmenaquinone hydratase/ synthetase: -2-oxoglutarate 5-methyltetrahydropteroyltriglutamate- methyltransferase: metE biosynthesis I assimilation cycle III tRNA ligase: C4H07_RS07505 tryptophan 2,3- C4H07_RS05530 C4H07_RS12260 glycosylase/ C4H07_RS01515 C4H07_RS00400 methyltransferase/2- dehydrogenase/ C4H07_RS10955 family protein: resistance/ family protein: diphosphate biosynthesis III C4H07_RS11835 aminomethyltransferase beta-ketoacyl-[acyl-carrier- acyltransferase: methyltransferase/2- isomerase C4H07_RS03700 transaminase: - homocysteine S- methionine methionine C4H07_RS04665 an L-tyrosyl- [+ 3 isozymes] acetyl-CoA dioxygenase: DNA-(apurinic methoxy-6-polyprenyl- class III alcohol C4H07_RS02235 C4H07_RS18065 C4H07_RS18065 kinase: L-glutamate methionine synthase: metH CO protein] synthase II: fabF [+ 6 isozymes] beta-ketoacyl- C4H07_RS00195 alpha-hydroxy-acid methoxy-6-polyprenyl- [+ 5 isozymes] family protein: a (3R)-3- aminoacyl-tRNA aldehyde dioxygenase synthase: L-ornithine degradation adenosyltransferase: Tyr 2 GcvT: gcvT 2-(glutathion- gabT C4H07_RS10705 asparagine asparagine methyltransferase: metE biosynthesis III ser ammonium glu glyoxylate [tRNA ] pro kynA or apyrimidinic 1,4-benzoquinol dehydrogenase: dehydrogenase aldehyde family protein: aldehyde serine RS18795 serine I (L-proline biosynthesis) Tyr N-Formyl-L- acyl-carrier protein a cis,cis-delta11,29-3-oxo-C48:2-[acp] 18-hydroxystearoyl- [acyl-carrier- 1-acyl-sn-glycerol- oxidizing protein: 1,4-benzoquinol S-yl)-3-(4- C4H07_RS02285 hydroxybutanoyl- hydrolase: synthase synthase methionine metH C4H07_RS04025 serine O- type I glutamate-- PLP-dependent a tRNA citrate L-serine degradation AMP diphosphate site) lyase: mutM bromide methylase UbiE: ubiE C4H07_RS19380 family protein: 4-aminobutyrate- dehydrogenase: C4H07_RS18930 dehydrogenase: dITP glycine L-homocysteine SAM hydroxylamine kynurenine CoA protein] 3-phosphate C4H07_RS13315 3-methyl-6-methoxy-methylase UbiE: ubiE nitrophenyl) 3-oxo-2-(cis-2'-pentenyl)[+ 7 isozymes] [acp domain within C4H07_RS06310 synthase: acetyltransferase: ammonia ligase: glnA an apurinic site 7,8-dihydro- -2-oxoglutarate (glutamine- (glutamine- 2-oxoglutarate biosynthesis IV aminotransferase a reduced c- menaquinol-11 phenylacetaldehyde a fatty acid synthase] Cys C4H07_RS18065 C4H07_RS10955 [+ 2 isozymes] C4H07_RS10955 L-ornithine met SAH gln SAH arylformamidase: synthase II: fabF within DNA 8-oxoguanine acyltransferase: pyruvate 2-octaprenyl-1,4- propanoate -cyclopentane-1-(E- a tRNA cys transaminase: hydrolyzing) hydrolyzing) metH NADP-specific C4H07_RS09115 family protein: a cis,cis-delta13,31- type cytochrome (2E)- a fatty acid (R)-lactate phytenate ornithine kynB ser acyl-carrier protein C4H07_RS182551-palmitoyl-2- benzoquinone buta-2-enoyl)-CoA C4H07_RS09140 sulfite RS13660 sulfite : asnB : asnB glutamate O-acetyl-L-serine C4H07_RS00865 L-aspartate 3-oxo-C50:2-[acp] hexadecenoate thr cyclodeaminase glutamate synthase: adenosylhomocysteinase: L-serine acyl-carrier protein cis-vaccenoyl 3-oxopropanoate met dehydrogenase: gly tryptophan-- L-glutamine degradation I low-specificity family protein: 5-methyltetrahydropteroyltriglutamate- C4H07_RS19390 a tRNA Trp C4H07_RS04010 L-kynurenine ammonia-lyase: phosphatidate C4H07_RS18025 cysteine synthase tRNA ligase: ammonium degradation I L-threonine - homocysteine S- + + asn asn C4H07_RS07505 adenosylhomocysteinase: CysM: cysM C4H07_RS19395 TCA cycle 2-aminoprop-C4H07_RS13495 H RS17195 H [+ 2 isozymes] aldolase: ltaE C4H07_RS14095 an L-tryptophanyl- asp pro methyltransferase: metE L-homocysteine β C4H07_RS04010 Trp gln kynureninase: 2-enoate (2E)- a 2-methyl 1-palmitoyl- all trans-decaprenyl- 3-oxo-2-(cis- poly- -1,6-N-acetyl- 3-oxo-2-(cis-2'-pentenyl) a 3-oxodecanoyl- 5-hydroxyindole D-glucurono- glu gly methionine synthase: metH glu [tRNA ] aspartate/ Carbohydrate Degradation a cis,cis-delta19- (R)-glycerate an L-cysteine- L-homocysteine S-ribosyl-L-homocysteine partial TCA cycle (obligate autotrophs) imidazole kynU a cis,cis-delta9,21-C40:2-[acp] a malonyl-[acp] hexadecenoate a malonyl-[acp] branched 2,3,4- sn-glycerol a myristoyl-[acp] 2-methoxy-6- 2'-pentenyl)- D-glucosamine DMKH2-10 -cyclopentane-1-(3R- 5-hydroxytryptophol [acp domain within L-selenocystathionine a lignoceroyl-[acp] acetaldehyde 6,3-lactone SAH cys trp tyrosine/aromatic L-phenylalanine degradation I (aerobic) 37-C56:2-[acp] S-conjugate IDP glycerol long-chain fatty saturated fatty acid 3-phosphate 1,4-benzoquinol cyclopentane-1- poly-beta-1,6- hydroxyoctanoyl)-CoA a fatty acid synthase] cystathionine glyoxylate/ aldehyde aldehyde aminotransferase: ketoacyl-ACP synthase ketoacyl-ACP long-chain fatty 1-acyl-sn-glycerol- bifunctional bifunctional enoyl-CoA S-(hydroxymethyl) enoyl-ACP cystathionine H + RS05765 H + phosphoenol tRNA processing phosphate anthranilate chitin degradation II (Vibrio) acid--CoA ligase: (3-oxooctanoyl) N-acetyl-D- acyl-CoA beta-lyase: hydroxypyruvate dehydrogenase: dehydrogenase: nucleoside- C4H07_RS05255 (6R)-4a-hydroxy- D-mannose III: C4H07_RS12260 synthase III: acid--CoA ligase: 3-phosphate demethylmenaquinone demethylmenaquinone hydratase/ glutathione reductase beta-lyase: pyruvate acetyl-CoA C- glucosamine synthetase: diphosphate synthase: tetrahydrobiopterin 4a-hydroxytetrahydrobiopterin 2-iminopropanoate degradation beta-ketoacyl-[acyl-carrier- C4H07_RS01755 C4H07_RS12260 C4H07_RS15820 acyltransferase: methyltransferase/2- -CoA methyltransferase/2- isomerase dehydrogenase/ metC FabI: fabI reductase A: C4H07_RS10955 C4H07_RS10955 metC [+ 2 isozymes] acyltransferase: N-deacetylase C4H07_RS02235 kinase: a polycistronic hisH hisF dehydratase: chitin [+ 6 isozymes] C4H07_RS00195 methoxy-6-polyprenyl- class III alcohol cystathionine C4H07_RS09530 aldehyde aldehyde threonine- oxaloacetate D-mannopyranose protein] synthase II: fabF beta-ketoacyl- [+ 6 isozymes]a 2-methyl methoxy-6-polyprenyl- C4H07_RS01465 family protein: a (3R)-3- enoyl-ACP cystathionine + + thr phosphoenolpyruvate tRNA precursor PgaB: pgaB C4H07_RS10705 H RS12805 H Nucleoside and Nucleotide Biosynthesis [+ 7 isozymes] C4H07_RS16130 (2E)- [acyl-carrier- 1,4-benzoquinol 3-oxo-2-(cis- 1,4-benzoquinol C4H07_RS02285 dehydrogenase: hydroxydecanoyl- beta-lyase: reductase FabI: glyoxylate/ dehydrogenase dehydrogenase Carbohydrate Biosynthesis -tRNA carboxylase: 6-phosphate acyl-carrier protein a cis,cis-delta11,23-3-oxo-C42:2-[acp] AMP diphosphate branched 1-acyl-sn-glycerol- [+ 3 isozymes] partially deacetylated beta-lyase: acetyl-CoA glu L-glutamine mannose-6- hexadecenoyl-CoA protein] AMP diphosphate methylase UbiE: ubiE 2'-pentenyl)- β methylase UbiE: ubiE C4H07_RS19380 [acp domain within metC C4H07_RS03235 hydroxypyruvate family protein: family protein: ITP ligase: thrS an L-threonyl- C4H07_RS18790 2,3,4-saturated 3-phosphate 6-methoxy-3-methyl- acetyl-CoA acetate poly- -1,6-N-acetyl- 3-oxo-2-(cis-2'-pentenyl)[+ 7 isozymes] 5-hydroxyindole metC superpathway of purine nucleotides de novo biosynthesis I degradation II phosphate cyclopentane-1- menaquinol-10 a fatty acid synthase] seleno-L- a trans-tetracos- reductase A: C4H07_RS18065 C4H07_RS18065 Thr pyruvate synthase II: fabF fatty acyl-CoA acyltransferase: 2-all-trans-decaprenyl- D-glucosamine -cyclopentane-1-(E- pyruvate pyruvate a thiol superpathway of guanosine superpathway of pyrimidine deoxyribonucleotides gluconeogenesis I [tRNA ] isomerase: hexanoyl-CoA acetaldehyde homocysteine 2-enoyl-[acp] 5-hydroxyindole trehalose ADP-L-glycero-β-D-manno UDP-2,3-diacetamido- a tRNA Thr (6R)-L-erythro-5,6,7,8- L-erythro-7,8- a chitodextrin a cis,cis-delta21,39- C4H07_RS18255 1,4-benzoquinol C4H07_RS18445 D-glucarate F0F1 ATP nucleotides de novo biosynthesis I de novo biosynthesis I acyl-carrier protein 1-palmitoyl- octa-2-enoyl)-CoA acetate + H + adenosine nucleotides biosynthesis V -heptose biosynthesis oxaloacetate a tRNA precursor a tRNA precursor tetrahydrobiopterin dihydrobiopterin C4H07_RS15225 3-oxo-C58:2-[acp] H synthase PRPP 2,3-dideoxy-α-D- gln acyl-carrier protein 2-myristoyl hydroxypyruvate de novo biosynthesis I (S)-malate with a 5' F6P UDP CTP Metabolic Regulator D-sedoheptulose mannuronate biosynthesis with a 5' glutamate synthase: phosphatidate ribonucleotide- Biosynthesis a glycogen UDP-N-acetyl- extension and extension and a IMP 7-phosphate Ldh family citrate synthase: C4H07_RS19390 amidophosphoribosyltransferase: purF IMP asp malate isoamylase: phosphoheptose α-D-glucosamine aspartate/ a long 3' trailer diphosphate serine- short 3' extension C4H07_RS19395 a chitodextrin CDP ppGpp biosynthesis dehydrogenase, glgX tyrosine/aromatic oxidoreductase: C4H07_RS11835 ribonuclease P a 3-methyl- 1-cis-vaccenoyl- a 3-oxooctanoyl- (E)-2- a (2E,9Z)- a [protein]- IMP adenylosuccinate reductase: isomerase: glu (15Z)- 2-all trans-hexaprenyl- a [protein] N-terminal- 3-oxo-2-(cis- an L-asparaginyl- a [protein]-L- gly NAD-requiring: -tRNA aminotransferase: C4H07_RS05685 a cis,cis-delta17,29- a cis- DMKH2-13 (R)-glycerate palmitaldehyde 5-phospho-β-D-ribosylamine synthase: a maltodextrin C4H07_RS17930 ser protein component: a cis,cis-delta7,25-C44:2-[acp] a malonyl-[acp] tetracosenoate a malonyl-[acp] branched 2,3,4- sn-glycerol- formyl-L-methionine 2'-pentenyl)- [acp domain within methylcrotonoyl- Asn octadeca-2,9- L-tyrosine dehydrogenase: C4H07_RS04510 ribonucleotide- D-glycero-D- UDP-N-acetyl-α-D- ligase: C48:2-[acp] vaccenoyl-[acp] 6-methoxyhydroquinone GTP H O GMP [tRNA ] methionine C4H07_RS14175 C4H07_RS05255 [+ 2 isozymes] C4H07_RS01560 long-chain fatty saturated fatty acid 3-phosphate peptide 2 a fatty acid synthase] CoA glyoxylate/ aldehyde dienoyl-[acp] phosphate peptide- guaB C4H07_RS10775 C4H07_RS04515 diphosphate pppGpp manno-heptose glucosaminouronate citrate ribonuclease PH: ketoacyl-ACP synthase ketoacyl-ACP long-chain fatty 1-acyl-sn-glycerol- bifunctional cyclopentane-1- bifunctional aminoacyl-tRNA enoyl-ACP adenylo-succinate Ldh family malto- serS an L-seryl- a tRNA precursor ribosome 5'-3'- acyl-CoA enoyl-CoA low molecular dUDP bifunctional (p)ppGpp [+ 2 isozymes] C4H07_RS07930 III: C4H07_RS12260 acid--CoA ligase: synthase III: acid--CoA ligase: 3-phosphate demethylmenaquinone deformylase: (3-oxobutanoyl) demethylmenaquinone hydrolase: hydroxypyruvate dehydrogenase reductase FabI: methionine reductase: oxidoreductase: oligosyltrehalose 7-phosphate ser synthetase: hydratase/ weight phosphoribosylamine- synthetase/guanosine- [tRNA ] bifunctional 2- with a short C4H07_RS01755 C4H07_RS12260 methyltransferase/2- C4H07_RS00210 -CoA acetyl-CoA C- methyltransferase/2- small subunit- deoxyribonucleotidase: reductase A: family protein: C4H07_RS03235 (S)-S-oxide XMP C4H07_RS04510 D-glycero- ser (S)-malate beta-N- beta-ketoacyl-[acyl-carrier- C4H07_RS15820 acyltransferase: C4H07_RS03700 phosphotyrosine -glycine ligase: purD adenylosuccinate nucleoside- 3',5'-bis(diphosphate) 3'- C4H07_RS05685 NADP-dependent synthase: treY a tRNA methylcitrate a tRNA 3' extension dependent C4H07_RS18395 C4H07_RS02235 isomerase C4H07_RS18445 beta-D- [+ 6 isozymes] [+ 6 isozymes] C4H07_RS00195 methoxy-6-polyprenyl- peptide acyltransferase: methoxy-6-polyprenyl- a (3R)-3- C4H07_RS18065 reductase lyase: purB diphosphate C4H07_RS04515 malic enzyme: a maltooligosyl- UDP-2-acetamido- asp Carboxylate Degradation acetylhexosaminidase: protein] synthase II: fabF beta-ketoacyl- a 3-methyl- GTPase A: rsgA family protein: aminoacyl-tRNA enoyl-ACP protein pyrophosphohydrolase: [+ 2 isozymes] class II dehydratase/ precursor with 1,4-benzoquinol deformylase: C4H07_RS01465 1,4-benzoquinol [+ 2 isozymes] aldehyde MsrA: msrA glutamine kinase: C4H07_RS16805 manno- α nagZ acyl-carrier protein a cis,cis-delta9,27-3-oxo-C46:2-[acp] (15Z)- [acyl-carrier- branched 1-acyl-sn-glycerol- hydroxyoctanoyl- C4H07_RS02285 hydrolase: glyoxylate/ reductase phosphatase: a protein-L- dCDP C4H07_RS07870 trehalose 2-deoxy- -D-ribo fumarate aconitate a 5' extension N,N'- N,N',N''- AMP diphosphate diphosphate AMP methylase UbiE: ubiE (+)-7-epi- methylase UbiE: ubiE [+ 3 isozymes] guanosine dehydrogenase: GAR amidotransferase: C4H07_RS10705 heptose-7- ribonuclease PH: tetracosenoyl-CoA protein] 2,3,4-saturated 3-phosphate 2-all-trans-hexaprenyl- C4H07_RS01870 [+ 3 isozymes] [acp domain within C4H07_RS06310 hydroxypyruvate FabI: fabI C4H07_RS10435 methionine- bifunctional (p)ppGpp NADP-dependent -hex-3-uluronate hydratase: crotonate fermentation (to acetate diacetylchitobiose triacetylchitotriose acetyl-CoA + [+ 7 isozymes] AMP nucleoside- bifunctional (p)ppGpp malto- phosphate hydratase: C4H07_RS07930 glutaryl-CoA an N-terminal L- jasmonoyl-CoA phosphate GDP H 3-hydroxyisovaleryl- reductase A: C4H07_RS10955 a [protein]- C4H07_RS12610 pyruvate fermentation citrate degradation synthase II: fabF fatty acyl-CoA acyltransferase: 6-methoxy-3-methyl- formate menaquinol-13 a fatty acid synthase] tRNA Asn asn an oleoyl-[acp] (S)-S-oxide dUTP synthetase/guanosine- malic enzyme: oligosyltrehalose proline-- fumC C4H07_RS11895 ribonuclease P and cyclohexane carboxylate) beta-N- methionyl-[protein] L-tyrosine diphosphate synthetase/guanosine- kinase: rfaE1 pro degradation to acetate IV a cis,cis-delta19,31- C4H07_RS18255 1,4-benzoquinol CoA C4H07_RS09530 palmitate glutamine- 3',5'-bis(diphosphate) 3'- C4H07_RS14175 β tRNA ligase: [+ 3 isozymes] protein component: acetylhexosaminidase: acyl-carrier protein 1,2-dicis- dUTP kinase: 3',5'-bis(diphosphate) 3'- trehalohydrolase: D-glycero- -D- an acetyl-holo 3-oxo-C50:2-[acp] hydroxypyruvate hydrolyzing GMP adenylate kinase: pyrophosphohydrolase: pyruvate C4H07_RS16255 fumarate C4H07_RS01560 crotonate nagZ acyl-carrier protein vaccenoyl- C4H07_RS10705 pyrophosphohydrolase: oxaloacetate treZ manno-heptose UDP-2-acetamido-3- an L-prolyl- glutaryl-CoA pyruvate [citrate lyase acyl- citrate synthase: guaA C4H07_RS05740 diphosphatase: C4H07_RS07870 cis-aconitate phosphatidate FGAR C4H07_RS17475 1,7-bisphosphate amino-2,3-dideoxy- [tRNA Pro ] acyl-CoA carrier protein] citrate lyase N-acetyl-D- C4H07_RS06740 dCTP α,α-trehalose phosphoenolpyruvate D-glycero- α-D-glucuronate a tRNA Pro dehydrogenase: subunit beta: glucosamine phosphoribosylformylglycinamidine GMP dUMP bifunctional 2- ADP synthase: ppsA beta-D-manno- C4H07_RS07665 C4H07_RS08655 a long-chain L-alanyl-γ-D- a 2'- S-(6-hydroxy- (2E)-tetradec- a 3-oxododecanoyl- (2E,9Z)- a protein-L- synthase: purL methylcitrate an uncharged (E)-glutaconyl- 18-hydroxyoleate a cis,cis-delta15,27- (S)-4-hydroxymandelate 3-methoxy-4- a glutaryl-[acp] (R)-glycerate salicylaldehyde acetyl-CoA thymidylate heptose 1,7- CoA ester lyase: a cis,cis-delta5,23-C42:2-[acp] a malonyl-[acp] a malonyl-[acp] 2,3,4-saturated UDP-N-acetyl- glutamyl-meso-2,6- deoxyribonucleoside [DNA] DMK-12 4-methylhexan- 2-enoyl-CoA [acp domain within hexadecenoyl-CoA methionine- succinate dehydratase/ tRNA crotonyl-CoA CoA hydroxyphenylglycol methyl ester dITP synthase: phosphoenol bisphosphate 7- long-chain fatty C46:2-[acp] fatty acid α-D-muramate mandelate racemase: 5'-triphosphate enoyl-CoA a fatty acid synthase] enoyl-CoA glyoxylate/ aldehyde acetyl-CoA (R)-S-oxide FGAM guanylate kinase: ribonucleotide- UDP-2,3-diacetamido- aconitate acyl-CoA acetyl-CoA formate a citryl-holoC4H07_RS13055 ketoacyl-ACP synthase ketoacyl-ACP long-chain fatty diaminopimeloyl- S-(hydroxymethyl) DNA polymerase bifunctional 4-yl)-L-cysteinecystathionine enoyl-ACP peptide- C4H07_RS03540 pyruvate phosphatase: α ADP- Secondary Metabolite Degradation acid--CoA ligase: UDP-N- C4H07_RS13000 hydratase acyl-CoA hydratase/ hydroxypyruvate dehydrogenase carboxylase RdgB/HAM1 family C4H07_RS07880 diphosphate GTP ppGpp 2,3-dideoxy- - phenylalanine-- hydratase: dehydrogenase: [citrate lyase acyl- III: C4H07_RS12260 synthase III: acid--CoA ligase: D-alanine glutathione III subunit demethylmenaquinone beta-lyase: reductase FabI: methionine superpathway of pyrimidine phosphopyruvate gmhB phe forming acyl-CoA enoyl-CoA C4H07_RS05530 acetylmuramate:L- family protein: synthetase: isomerase reductase A: family protein: biotin carboxyl non-canonical phosphoribosylformylglycinamidine reductase: dTMP D-glucuronate tRNA ligase: pheS C4H07_RS11895 phosphate carrier protein] beta-ketoacyl-[acyl-carrier- C4H07_RS12260 C4H07_RS05530 mandelate racemase/ dehydrogenase/ gamma/tau: methyltransferase/2- metC C4H07_RS03235 (R)-S-oxide nucleobases salvage O-antigen building blocks biosynthesis (E. coli) D-glycero-β-D- dehydrogenase: hydratase C4H07_RS07665 alanyl-gamma-D- C4H07_RS02235 purine NTP C4H07_RS04510 hydratase: C4H07_RS06765 succinate- acetyltransferase: citryl-CoA lyase: ketogluconate metabolism [+ 6 isozymes] muconate lactonizing class III alcohol methoxy-6-polyprenyl- C4H07_RS18325 family protein: C4H07_RS09530 C4H07_RS18065 carrier protein: cyclo-ligase: C4H07_RS18650 GDP manno-heptose an L-phenylalanyl- [+ 3 isozymes] protein] synthase II: fabF beta-ketoacyl- [+ 6 isozymes] C4H07_RS07735 cystathionine a (3R)-3- enoyl-ACP pyrophosphatase: reductase C4H07_RS04515 dTMP kinase: C4H07_RS11970 α -CoA queuosine biosynthesis C4H07_RS07665 family protein: C4H07_RS14775 a long-chain glutamyl- meso- dehydrogenase: 1,4-benzoquinol [+ 7 isozymes] C4H07_RS02285 C4H07_RS04445 uracil UDP- -D- α-D- D-glucopyranose [tRNA Phe ] crotonyl-CoA C4H07_RS02475 18-hydroxyoleoyl- [acyl-carrier- enzyme family protein: [+ 8 isozymes] (S)-3- hydroxydodecanoyl- reductase glyoxylate/ aldehyde MsrB: msrB C4H07_RS08590 1-phosphate C4H07_RS18325 acyl-carrier protein a cis,cis-delta7,25-3-oxo-C44:2-[acp] AMP diphosphate diaminopimelate beta-lyase: rdgB AIR uracil 2-phospho- galactose Phe ligase: D-threo-isocitrate [+ 3 isozymes] 2,5-didehydro- AMP diphosphate 2,3,4-saturated C4H07_RS14005 C4H07_RS19380 methylase UbiE: ubiE [+ 7 isozymes] dehydrogenase: [+ 5 isozymes] a [protein]-L- nucleoside- glucopyranose 6-phosphate UDP-2,3-diacetamido- a tRNA CoA protein] UDP-N-acetylmuramoyl- [DNA] metC hydroxytetradecanoyl- [acp domain within FabI: fabI hydroxypyruvate dADP glucose-6- heptose 1-phosphate sucC sucD (E)-glutaconyl- [+ 7 isozymes] enoyl-CoA acetyl phosphate D-gluconate fatty acyl CoA ligase: mpl 3-methoxy-4- (S)-3-hydroxy-(9Z) C4H07_RS10955 dIMP methionine dTDP phosphoribosyltransferase: diphosphate bifunctional (p)ppGpp D-glycerate 1-phosphate 2,3-dideoxy-α- preQ synthase II: fabF γ (R)-4-hydroxymandelate menaquinol-12 3-methyl-3- CoA a fatty acid synthase] an enoylglutaryl- reductase A: malonyl-CoA 5-(carboxyamino) nucleoside- ribonucleotide- bifunctional (p)ppGpp phosphate adenyltransferase: NADP-dependent 0 CoA hydratase oxaloacetate L-alanyl- -D- hydroxyphenylglycolaldehyde pyruvate -hexadecenoyl-CoA nucleoside- C4H07_RS14540 kinase: synthetase/guanosine- 2,3- UDP-Galf D-mannuronate NADPH-dependent 7- (S)-3- a cis,cis-delta17,29- sulfanylhexan-1-ol [acp] methyl ester C4H07_RS18445 salicylate imidazole ribonucleotide diphosphate diphosphate synthetase/guanosine- dTDP-α-D-glucose isomerase: C4H07_RS01295 succinyl-CoA isocitrate acyl-CoA family protein: acetate kinase: acyl-carrier protein glutamyl-meso-2,6- nucleoside- UMP C4H07_RS10705 cyano-7-deazaguanine D-glucosaminate degradation 3-oxo-C48:2-[acp] hydroxypyruvate mutase: purE diphosphate 3',5'-bis(diphosphate) 3'- 3',5'-bis(diphosphate) 3'- diphosphoglycerate- ADP-D-glycero-β- dehydrogenase: hydroxybutanoyl- C4H07_RS18325 diaminopimeloyl- kinase: reductase: diphosphate C4H07_RS03600 dehydrogenase: reductase QueF: queF C4H07_RS14780 kinase: UMP kinase: pyrophosphohydrolase: pyrophosphohydrolase: dependent dTDP- methionine- CoA D-alanine 5-(carboxyamino) C4H07_RS10705 C4H07_RS04510 kinase: glucose-6- D-manno-heptose met C4H07_RS07220 preQ C4H07_RS07665 [+ 7 isozymes] C4H07_RS12690 phosphoglycerate glucose 4,6- 1 2-amino-2-deoxy- C4H07_RS10705 C4H07_RS17475 C4H07_RS17475 -tRNA 3-hydroxyacyl-CoA (S)-3- acetate 2-keto-L-gulonate imidazole ribonucleotide C4H07_RS04515 C4H07_RS10705 phosphate ADP- D-gluconate (d)CMP kinase: mutase: gpmA dehydratase: ligase: metG an L-methionyl- 2-oxoglutarate glutaryl-CoA dehydrogenase: PTS sugar γ dTTP bifunctional (p)ppGpp isomerase: glyceromanno- hydroxybutanoyl- L-alanyl- -D- 3-benzyl-3,6- 2251 an [amino group carrier (2E,11Z)- 3S-(4- synthase: rfbB UDP-α-D-glucose [elongator tRNA guanosine(34) a cis,cis-delta13,25- UDP-N-acetyl- a (6S)-5- guanosine a (5Z)-dodec- a secondary C4H07_RS15055 synthetase/guanosine- histidine heptose 6- C4H07_RS08935 CoA transporter 2,5- a cis,cis-delta3,21-C40:2-[acp] a malonyl-[acp] an acetyl-[acp] a malonyl-[acp] a malonyl-[acp] pentadecanoate glutamyl-meso- demethylmenaquinol-4 dihydroxy-6- glu protein]-C-terminal-γ- (S)-lactaldehyde butan-1-ol a protein C4H07_RS07615 GTP dATP C4H07_RS09110 elongator Met transglycosylase Tgt: tgt sarcosine in 23S rRNA octadecenoyl-CoA hydroxyphenyl) alcohol dTDP-4-dehydro- biosynthesis I tRNA ] NADP-specific didehydrogluconate C44:2-[acp] α-D-muramate glutathione formyltetrahydrofolate AMP 5-enoyl-[acp] phosphatase epimerase: rfaD Met 3-hydroxyacyl-CoA subunit IIA: diaminopimelate (hydroxymethyl) 23S rRNA (L-glutamyl)-L-glutamate enoyl-CoA aldehyde dGDP UDP 3',5'-bis(diphosphate) 3'- F6P tRNA glutamate acetoacetyl-CoA ketoacyl-ACP synthase ketoacyl-ACP synthase ketoacyl-ACP long-chain fatty UDP-N- bifunctional bifunctional sarcosine oxidase: enoyl-ACP -3-hydroxy- S-(hydroxymethyl) S-(hydroxymethyl) metalloprotease asp CAIR family protein: 6-deoxy-α-D- β D-glucopyranose a 7-aminomethyl-7- dehydrogenase: C4H07_RS02590 reductase DkgB: dkgB glutathione S- 5'-3'- pyrophosphohydrolase: ADP-L-glycero- - 34 III: C4H07_RS12260 III: C4H07_RS12260 synthase III: acid--CoA ligase: demethylmenaquinone -diketopiperazine (guanosine(2251) acetylglutamate hydratase/ reductase FabI: dehydrogenase propanoyl-CoA glutathione glutathione PmbA: pmbA nucleoside-diphosphate glucopyranose dehydrogenase: deazaguanosine in tRNA 2-amino-2-deoxy-D- L-idonate acetylmuramate:L- transferase: tetrahydrofolate C4H07_RS07065 enoyl-CoA C4H07_RS07870 C4H07_RS12500 glutamine-- D-manno-heptose 6-phosphate 3-oxopimeloyl- acetyl-CoA C- C4H07_RS08935 C4H07_RS12260 C4H07_RS05530 methyltransferase/2- deoxyribonucleotidase: -2'-O)- kinase: argB isomerase C4H07_RS03235 family protein: dehydrogenase/ dehydrogenase/ nucleoside- inosine-5'-phosphate biosynthesis I kinase: C4H07_RS10705 GDP phosphomannomutase/ C4H07_RS18025 gluconate 6-phosphate beta-ketoacyl-[acyl-carrier- beta-ketoacyl-[acyl-carrier- alanyl-gamma-D- synthase/ C4H07_RS07070 hydratase/ metalloprotease 3-phospho- dTDP-4- fructose-6- tRNA preQ1(34) S- CoA acyltransferase: C4H07_RS00400 C4H07_RS18395 methyltransferase family protein: C4H07_RS18065 class III alcohol phosphoribosylaminoimidazolesuccinocarboxamide diphosphate phosphoglucomutase: [+ 2 isozymes] protein] synthase II: fabF protein] synthase II: fabF [+ 6 isozymes] glutamyl- meso- methoxy-6-polyprenyl- 3-benzyl-3,6 - dihydrofolate C4H07_RS07075 an [amino group carrier enoyl-ACP isomerase class III alcohol TldD: tldD UTP dehydrorhamnose adenosylmethionine acetoacetyl-CoA beta-ketoacyl- [+ 5 isozymes] [+ 2 isozymes] synthase: C4H07_RS07585 D-glycerate phosphate C4H07_RS09105 lysine- C4H07_RS02450 1,4-benzoquinol RlmB: rlmB C4H07_RS02285 aldehyde dehydrogenase: dehydrogenase: kinase: Lys acyl-carrier protein a cis,cis-delta5,23-3-oxo-C42:2-[acp] an acetoacetyl-[acp] acyl-carrier protein [acyl-carrier- pentadecanoyl- diaminopimelate bis(glutathione)- synthase: folC C4H07_RS07080 2-O- protein]-C-terminal- reductase family protein: a peptide AIR 3,5-epimerase: rfbC transaminase a tRNA ribosyltransferase- AMP diphosphate CTP synthase: -tRNA [+ 5 isozymes] acetyl-CoA C- methylase UbiE: ubiE a (6S)-5- adenosine 2251 γ [+ 7 isozymes] FabI: fabI dehydrogenase: C4H07_RS19380 C4H07_RS19380 C4H07_RS10705 phosphoglycerate dTDP-4-dehydro- phosphomannomutase/ glu isomerase QueA: queA 5-dehydro- protein] CoA UDP-N-acetyl-ligase: mpl 6-(hydroxymethyl) formaldehyde gly methylguanosine -(5-phospho-L- C4H07_RS02285 (isomerizing) 2-methylcitrate cycle I formyltetrahydrofolate (S)-3-hydroxy-(11Z) a (3E,5Z)-dodeca- C4H07_RS10955 C4H07_RS11985 kinase: pgk phosphoglucomutase: ligase: lysS an L-lysyl- 3-hydroxypimeloyl- acyltransferase: synthase II: fabF α menaquinol-4 -diketopiperazine in 23S rRNA glutamyl)-L-glutamate [+ 7 isozymes] a ketone butan-1-al SAICAR 5-(carboxyamino)imidazole β-L-rhamnose : glmS acetyl-CoA KDGP D-gluconate -D-muramoyl- -octadecenoyl-CoA (E)-4- dGTP CTP C4H07_RS03605 [tRNA Lys ] an epoxyqueuosine 34 in tRNA C4H07_RS02450 2-keto-D- a cis,cis-delta15,27- 3,5-dienoyl-[acp] (S)-lactate ribonucleotide synthase: Amine and Polyamine Biosynthesis dTDP-4- α-D-glucopyranose CoA acyl-carrier protein L-alanyl-γ-D- coumaroyl-CoA 13-DPG D-glucosamine lys CoA-binding [+ 5 isozymes] propanoate gluconate 3-oxo-C46:2-[acp] adenylosuccinate C4H07_RS07615 dehydrorhamnose 1-phosphate epoxyqueuosine SDR family glutamyl-meso-2,6- 6-phosphate protein: lyase: purB pyrimidine deoxyribonucleotide reductase: rfbD reductase QueH: acetyl-CoA oxidoreductase: diaminopimelate N5-CAIR spermidine biosynthesis I type I UTP--glucose- C4H07_RS02415 cadaverine dTDP-β-L- phosphoglucosamine 2-hydroxy-6- D-glyceraldehyde C4H07_RS01380 phosphorylation glyceraldehyde- 1-phosphate C4H07_RS13490 pyruvate AICAR biosynthesis rhamnose mutase: glmM propanoyl-CoA 3-phosphate Glycolysis oxocyclohexane- 1518 (E)-1-(L-cystein-S- a [protein]-L- 2030 a 3-oxohexadecanoyl- a (3R)-3- a (2E,5Z)- 5-(carboxyamino)imidazole dTMP dCMP 3-phosphate GDP-mannose biosynthesis uridylyltransferase 34 acetate a DNA methyl a [protein]- adenine / adenine (2R,3S)-3- α α-D-glucosamine histidine- a queuosine in tRNA an N-formyl-L- a cis,cis-delta11,23- pristanate sn-glycerol 5 a pimeloyl-[acp] perillyl aldehyde propan-1-ol phytol a 1,4- -D-glucan SAM his 1-carbonyl-CoA D-gluconate a cis,cis-delta7,19-C38:2-[acp] a malonyl-[acp] a malonyl-[acp] phosphotriester a stearoyl-[acp] 1519 yl)-N-hydroxy-2-(4- glutamate-O [acp domain within hydroxydodecanoyl- tetradeca-2,5- bifunctional UMP biosynthesis II ribonucleotide mutase: purE dTMP kinase: (d)CMP kinase: triose-phosphate dehydrogenase: GalU: galU 2-methylcitrate L-cysteine adenine in 16S rRNA in 23S rRNA isopropylmalate methyl ester lys 1-phosphate -tRNA methionylaminoacyl-tRNA C42:2-[acp] long-chain fatty 3-phosphate 16S rRNA hydroxyphenyl)ethan-1-imine -methyl-ester 23S rRNA a fatty acid synthase] 3-isopropylmalate aldehyde dienoyl-[acp] 1,4-alpha- phosphoribosylaminoimidazolecarboxamide C4H07_RS08590 C4H07_RS15055 isomerase: gap D-glucopyranose glycolysis I (from glucose 6-phosphate) synthase: prpC ketoacyl-ACP synthase peptide deformylase: ketoacyl-ACP methylated-DNA-- glycerol-3- cystathionine chemotaxis [acp domain within enoyl-ACP enoyl-ACP S-(hydroxymethyl) S-(hydroxymethyl) asp lysine UDP-α-D-glucose ligase: hisS an L-histidyl- acid--CoA ligase: (adenine(1518)-N(6)/ (adenine(2030)-N(6) acyl-CoA dehydratase: dehydrogenase: glucan formyltransferase/IMP cyclohydrolase: purH CAIR dTDP dCDP C4H07_RS15420 UDP-N- 6-phosphate III: C4H07_RS12260 C4H07_RS00210 synthase III: [protein]-cysteine S- phosphate 1-O- beta-lyase: metC response regulator a fatty acid synthase] reductase FabI: reductase FabI: glutathione glutathione decarboxylase: D-glyceraldehyde glucose-6- [tRNA His ] (2S,3S)-2- C4H07_RS15820 adenine(1519)-N(6))- synthetase: acyl-CoA branching hydrogencarbonate gln putrescine dAdoMet DHAP acetylglucosamine D-glucopyranose 6-oxocyclohex- beta-ketoacyl-[acyl-carrier- C4H07_RS12260 methyltransferase: acyltransferase cystathionine protein-glutamate )-methyltransferase leuD leuC C4H07_RS03235 C4H07_RS10955 C4H07_RS03235 dehydrogenase/ dehydrogenase/ FAICAR nucleoside- nucleoside- 3-phosphate phosphate a tRNA His methylcitrate 3-oxoadipate peptide deformylase: C4H07_RS02235 synthetase: protein C4H07_RS18915 diphosphorylase/ 6-phosphate 5-oxo-L-proline metabolism 1-ene-1- D-gluconate [+ 6 isozymes] C4H07_RS17915 dimethyltransferase RlmJ: 3-isopropylmalate aldehyde class III alcohol class III alcohol phosphoribosylaminoimidazolesuccinocarboxamide diphosphate diphosphate isomerase: degradation protein] synthase II: fabF C4H07_RS01870 beta-ketoacyl- PlsY:1-stearoyl- plsY (Z)-N-hydroxy-2-beta-lyase: metC methylesterase: a (3R)-3- C4H07_RS02235 enoyl-ACP enoyl-ACP spermidine cadaverine glucosamine-1- pyruvate decarboxylation to acetyl CoA bifunctional 2- 6-phosphate RsmA: rsmA C4H07_RS10080 a (2E)-dodec-2-enoyl- dehydrogenase: dehydrogenase: GlgB: glgB bifunctional carbamoyl-phosphate carbonyl-CoA [acyl-carrier- methylated-DNA-- acyl-carrier protein N 6 -dimethyladenine 1518 C4H07_RS14645 an N 6 - hydroxyhexadecanoyl- dehydratase reductase dehydrogenase reductase a (1,6)-α-D-glucosyl- synthase: C4H07_RS07585 kinase: kinase: synthase: trehalose C4H07_RS03600 glucose-6- a [protein] with a [protein] with methylcitrate acyl-carrier protein a cis,cis-delta9,21-3-oxo-C40:2-[acp] formate a L-methionylaminoacyl-tRNA AMP diphosphate pristanoyl-CoA sn-glycerol pyruvate (4-hydroxyphenyl) α [acp domain within phosphate N- [protein]-cysteine S- 6 1519 a [protein]- - 2030 small subunit: leuD family protein: C4H07_RS19380 C4H07_RS19380 phosphoribosylaminoimidazolecarboxamide synthase large C4H07_RS10705 C4H07_RS10705 pyruvate 3-oxoadipate protein] 3-phosphate /N -dimethyladenine acetimidothioate MeOH methyladenine [acp domain within FabI: fabI FabI: fabI (1,4)-α-glucan C4H07_RS11465 fructose- biosynthesis IV acetyltransferase: glucose-6- PRPP biosynthesis phosphate an N-terminal an N-terminal dehydratase/ L-glutamate a fatty acid synthase] (2S)-2- an enoylpimeloyl- a (5Z)-tetradec- formyltransferase/IMP cyclohydrolase: purH subunit: carB a [pyruvate dehydrogenasedehydrogenase CoA transferase synthase II: fabF methyltransferase: in 16S rRNA in 23S rRNA a fatty acid synthase] C4H07_RS18065 1-propanal phytenal SAICAR phosphate isomerase: L-glutamine L-glutamate aconitate isopropylmalate dTTP dCTP bisphosphate glmU glycine--tRNA 6 a cis,cis-delta13,25- C4H07_RS18170 [acp] methyl ester 5-enoyl-[acp] spermidine α-maltose isomerase: D-ribose 5- gly C4H07_RS03600 6-hydroxycyclohex- E2 protein] N -lipoyl-L-lysine(acetyl- subunit B: acyl-carrier protein perillate carbamoyl phosphate asp aldolase class II: N-acetyl-α-D- ligase: glyQ hydratase: 3-oxo-C44:2-[acp] a [protein]-S- maltose alpha-D- C4H07_RS09110 phosphate 1-ene-1- transferring), C4H07_RS10390 [DNA] IMP adenylosuccinate C4H07_RS07575 glucosamine ribose-phosphate C4H07_RS00185 glucose-6- C4H07_RS11895 methyl-L-cysteine glucosyltransferase: F6P Gly carbonyl-CoA dihydrolipoyl homodimeric 3-oxoacid CoA- lyase: purB 1-phosphate pyrophosphokinase: a glycyl-[tRNA ] phosphate pyruvate cis-2- treS dehydrogenase: type: aceE transferase: aspartate C4H07_RS03690 a tRNA Gly isomerase: a [protein] with methylaconitate α,α-trehalose UDP-N- mannose-6- γ-L-glutamyl C4H07_RS18820 an E. coli 34 a 3-oxotetradecanoyl- a (3R)-3- carbamoyltransferase: AICAR PRPP C4H07_RS09110 an N-terminal 5- lpdA alpha- sn-glycerol a nucleoside a guanine a double stranded DNA a negatively sn-glycerol a 1,4-α-D-glucan β-D-fructose 1,6- acetylglucosamine phosphate 5-phosphate glutathione bifunctional a cis,cis-delta3,15-C34:2-[acp] a malonyl-[acp] osmoregulated an L-1- phytenate 3,4-dihydroxyphenylglycol a myristoyl-[acp] a ribonucleic acid cys queuine [acp domain within hydroxydecanoyl- a cis-2-enoyl-CoA an octanoyl-[acp] a butanoyl-[acp] isobutanol IMP dehydrogenase: C4H07_RS06835 oxo-L-proline cyclohex- [+ 3 isozymes] ketoglutarate C4H07_RS18825 ATP H O triphosphate in tRNA supercoiled DNA 3-phosphate 2 3-phosphate 1,4-alpha- bifunctional bisphosphate diphosphorylase/ isomerase: aconitate 3-oxoadipyl-CoA ketoacyl-ACP synthase periplasmic phosphatidylethanolamine long-chain fatty S-(hydroxymethyl) tRNA DNA gyrase a fatty acid synthase] [acp domain within DNA enoyl-CoA S-(hydroxymethyl) glycerol-3- guaB F6P 1,5-diene-1- dehydrogenase: EscN/YscN/HrcN family glycerol-3- DNA- cysteine dioxygenase: acyl-CoA enoyl-ACP enoyl-ACP aspartate phosphoribosylaminoimidazolecarboxamide glucosamine-1- C4H07_RS15225 hydratase 2/2- superpathway of acetate glucan (OPG) phosphoethanolamine acid--CoA ligase: guanosine(34) subunit A: gyrA a fatty acid synthase] topoisomerase III: hydratase/ glutathione glucan class 1 fructose- carbonyl-CoA mdeB III: C4H07_RS12260 glutathione phosphate 1-O- directed RNA C4H07_RS02705 reductase reductase phosphate 1-O- carbamoyltransferase: formyltransferase/IMP cyclohydrolase: purH phosphate N- transferase: type III secretion system synthetase: acyl-CoA branching bisphosphatase: D-mannopyranose methionine- a [pyruvate dehydrogenase a [pyruvate dehydrogenase methylisocitrate 3-oxoadipyl-CoA utilization and formation beta-ketoacyl-[acyl-carrier- C4H07_RS01755 dehydrogenase/ polymerase: cysteine dioxygenase: transglycosylase DNA C4H07_RS01400 isomerase FabI: fabI FabI: fabI dehydrogenase/ acyltransferase C4H07_RS18265 met dihydrolipoyllysine- an E. coli C4H07_RS11685osmoregulated ATPase: C4H07_RS09825 acyltransferase C4H07_RS02235 synthetase: C4H07_RS15765 acetyltransferase: 6-phosphate -tRNA class 1 fructose- 6 6 dehydratase: acnB thiolase: pcaF [+ 6 isozymes] class III alcohol Tgt: tgt topoisomerase III: family protein: class III alcohol protein FAICAR E2 protein] N - residue E2 protein] N -S- protein] synthase II: fabF a 1,2-diacyl- periplasmic glucan with PlsY:1-myristoyl- plsY rpoB rpoC C4H07_RS04375 a (3R)-3- C4H07_RS02235 DNA enoyl-ACP enoyl-ACP 1-(18- PlsY: plsY glmU ligase: metG bisphosphatase: 5-oxo-L-proline acetate type I secretion system dehydrogenase: C4H07_RS01400 a (2E)-dec-2-enoyl- C4H07_RS02285 dehydrogenase: GlgB: glgB phosphomannomutase/ an L-methionyl- dihydrolipoyl-L-lysine acetyltransferase:acetyldihydrolipoyl-L-lysine (2R,3S)-2- acetyl-CoA sn-glycerol [+ 2 isozymes] a queuosine 34 hydroxytetradecanoyl- topoisomerase reductase FabI: reductase FabI: hydroxyoleoyl) XMP F6P C4H07_RS15765 succinyl-CoA acyl-carrier protein a cis,cis-delta5,17-3-oxo-C36:2-[acp] phosphotidylethanolamine permease/ATPase: diphosphate AMP phytenoyl-CoA acyl-carrier protein sn-glycerol 3-sulfino-L-alanine guanine a negatively UDP-N-acetyl- Met cyclohex-1-ene- methylisocitrate synthetase: C4H07_RS19380 [acp domain within IV subunit A: parC [+ 7 isozymes] C4H07_RS19380 a GlgE-glycogen N-carbamoyl-L-aspartate bifunctional phosphoglucomutase: [initiator tRNA ] 5-oxoprolinase aceF substituent 3-phosphate a ribonucleic acid in tRNA [acp domain within C4H07_RS03235 C4H07_RS03235 -sn-glycrol α-D-glucosamine Met 1-carbonyl-CoA C4H07_RS15905 supercoiled DNA a fatty acid synthase] a (3R)-3- phosphoribosylaminoimidazolecarboxamide C4H07_RS03605 initiator tRNA β acetate kinase: C4H07_RS02270 3,4-dihydroxyphenylglycolaldehyde a fatty acid synthase] a relaxed DNA a (2E)-oct- a (2E)-but- isobutanal 3-phosphate glutamine glucose-6- -D-fructose 1,6- subunit + hydroxyacyl-CoA formyltransferase/IMP cyclohydrolase: purH C4H07_RS14780 [+ 3 isozymes] H phosphate ADP 2-enoyl-[acp] 2-enoyl-[acp] amidotransferase: dihydroorotase: pyrC phosphate phosphomannomutase/ bisphosphate PxpB: pxpB DHAP C4H07_RS12610 dihydroorotase: isomerase: phosphoglucomutase: 5-oxoprolinase: succinate pyruvate asp fructose- acetyl-CoA C4H07_RS18260 IMP C4H07_RS03600 C4H07_RS09105 C4H07_RS08820 cyclohexane-1- glutamine-hydrolyzing bisphosphate acetyl phosphate acetyl-CoA glucose-6- α-D-mannose carbonyl-CoA an [L-cysteine a (3R)-3- GMP synthase: guaA adenylosuccinate (S)-dihydroorotate triose-phosphate 32 (indol-3- a [release factor]- α aldolase class II: seleno-L- 2-oxoglutarate isovalerate decanoate a cytosine NaMN coenzyme A citrate a primary alcohol 3-methylbutanol Ap4A a 1,4- -D-glucan synthase: phosphate 1-phosphate isomerase: glu a cis,cis-delta5,17-C36:2-[acp] a malonyl-[acp] desulfurase]-S- L-cystathionine yl)pyruvate L-glutamine hydroxyoctanoyl- a cerotoyl-[acp] a myristoyl-[acp] asp C4H07_RS07575 homocysteine in tRNA 1,4-alpha- GMP C4H07_RS10775 quinone-dependent isomerase: C4H07_RS15420 ketoacyl-ACP synthase alpha-ketoglutarate acetyl-CoA long-chain fatty sulfanyl-L-cysteine tRNA 2- 5'-nucleotidase SurE: cystathionine indolepyruvate CoA ester lyase: peptide chain [acp domain within S-(hydroxymethyl) S-(hydroxymethyl) enoyl-ACP enoyl-ACP symmetrical 5-methyltetrahydropteroyltriglutamate- aspartate/ glucan dihydroorotate C4H07_RS09110 phosphate III: C4H07_RS12260 dehydrogenase: mdeB synthetase: acid--CoA ligase: thiocytidine(32) C4H07_RS10025 beta-lyase: metC ferredoxin C4H07_RS13055 release factor a fatty acid synthase] glutathione glutathione reductase reductase bis(5'-nucleosyl)- cyclohexane- - homocysteine S- acyl-CoA tyrosine/aromatic branching adenylo-succinate dehydrogenase: D-glucopyranose GDP-α-D- acetyltransferase: beta-ketoacyl-[acyl-carrier- 2-oxoglutarate C4H07_RS02270 C4H07_RS15820 synthetase 5'-3'- cystathionine oxidoreductase citrate lyase N(5)-glutamine dehydrogenase/ dehydrogenase/ FabI: fabI FabI: fabI tetraphosphatase: guanylate kinase: superpathway of 5-aminoimidazole Fatty Acid and Lipid Biosynthesis D-glyceraldehyde 1-carboxylate methyltransferase: metE synthetase: aminotransferase: protein C4H07_RS16725 6-phosphate mannose C4H07_RS14775 protein] synthase II: fabF dehydrogenase [+ 3 isozymes] [+ 6 isozymes] TtcA: ttcA deoxyribonucleotidase: beta-lyase: metC family protein: subunit beta: methyltransferase: class III alcohol class III alcohol C4H07_RS18250 ribonucleotide biosynthesis 3-phosphate 32 an [L-cysteine C4H07_RS02235 enoyl-ACP enoyl-ACP C4H07_RS05255 C4H07_RS07880 adenylosuccinate lipoprotein posttranslational modification E1 component: a 2-thiocytosine C4H07_RS18395 C4H07_RS04520 C4H07_RS08655 prmC a (2E)-oct-2-enoyl- dehydrogenase: dehydrogenase: GlgB: glgB acyl-carrier protein a cis,cis-delta7,19-3-oxo-C38:2-[acp] SeMet desulfurase]- pyruvate L-homocysteine 5 reductase FabI: reductase FabI: lyase: purB orotate palmitate biosynthesis II isovaleryl-CoA AMP diphosphate diphosphate AMP decanoyl-CoA in tRNA (indol-3 yl) a [release factor]-N [acp domain within C4H07_RS19380 C4H07_RS19380 [+ 2 isozymes] ADP a glycogen PRPP PRPP palmitoleate cis-vaccenate epoxysqualene type I C4H07_RS14155 L-cysteine β-D-ribosylnicotinate oxaloacetate acetate C4H07_RS03235 C4H07_RS03235 (bacteria and plant cytoplasm) a [prolipoprotein]- acetyl-CoA -methyl-L-glutamine a fatty acid synthase] oxaloacetate GDP biosynthesis I (from biosynthesis biosynthesis glyceraldehyde- NADH CO succinyl-CoA an aldehyde 3-methylbutanal a trans-hexacos- a (2E)-tetradec- L-cysteine 2 orotate amidophosphoribosyltransferase: purF 2-enoyl-[acp] 2-enoyl-[acp] AMP (5Z)-dodec-5-enoate) 3-phosphate Detoxification phosphoribosyltransferase: 5-phospho-β- an acetoacetyl-[acp] (2E,6E)-farnesyl prolipoprotein a (5Z)-dodec- a palmitoleoyl-[acp] dehydrogenase: pyrE D-ribosylamine diphosphate gap diacylglyceryl SDR family 5-enoyl-[acp] ketoacyl-ACP squalene reactive oxygen species degradation adenylate kinase: beta-ketoacyl- transferase: superoxide 2-amino-6-[1-hydroxyethyl]- an odd numbered α,ω-9Z- (E)-1-(L-cystein-S- a (7Z,10Z,13Z,16Z 4-hydroxy- a (3R)-3- a (3R)-3- an (2E,11Z) a (5Z)-3- (3R,5S)-3- orotidine 5'-phosphate phosphoribosylamine- oxidoreductase: synthase III: synthase arsenate arginine 3-demethylubiquinol-10 a ferricytochrome glutathione DMKH 2-methylbutanol a 1,4-α-D-glucan ribonucleotide- C4H07_RS05740 [acyl-carrier- C4H07_RS04190 radicals degradation a (5Z)-tetradec-5-enoyl-[acp] a malonyl-[acp] 7-methyl-7,8-dihydropterin straight chain octadecenedioate yl)-N-hydroxy-2-(1H- ,19Z)-3-oxodocosa- formate 2-nonenal hydroxyhexadecanoyl- N-acetyl-L-citrulline hydroxyhexanoyl- 2 a decanoyl-[acp] -icosa-2,11- oxododec- hydroxy-1- -glycine ligase: purD C4H07_RS14135 C4H07_RS12260 HpnC: 13-DPG Inorganic Nutrient Metabolism detoxification dependent b 1,4-alpha- diphosphate reductase: nucleoside- protein] a [prolipoprotein]- superoxide beta-ketoacyl-[acyl-carrier- 2-amino-4-hydroxy-6- 2,3,4-saturated bifunctional 2-polyprenyl-6- long-chain fatty indol-3-yl)ethan-1-imine 7,10,13,16,19-pentaenoyl-[acp]SDR family 1 glutathione S- [acp domain within acetylornithine [acp domain within bifunctional S-(hydroxymethyl) enoyl-ACP dienoyl-[acp]enoyl-ACP 5-enoyl-[acp]SDR family pyrroline-5- hpnC II (glutaredoxin) acid resistance cystathionine NAD-dependent glucan C4H07_RS04510 orotidine-5'-phosphate [+ 5 isozymes] synthase beta- S-1,2-diacyl-sn- superoxide protein] synthase II: fabF hydroxymethyldihydropteridine fatty acidlong-chain fatty hydroxyphenol methylase/ acid--CoA ligase: oxidoreductase: transferase: a fatty acid synthase] deacetylase: argE a fatty acid synthase] demethylmenaquinone glutathione reductase reductase FabI: oxidoreductase: carboxylatepyrroline-5- diphosphate kinase: GAR selenate reduction beta-lyase: metC formate acyl-CoA acyl-CoA C4H07_RS04515 ADP decarboxylase: pyrF ketoacyl- presqualene glyceryl-L-cysteine superoxide dismutase: arsenate diphosphokinase: acid--CoA ligase: 3-demethylubiquinol 3- C4H07_RS01755 C4H07_RS00400 methyltransferase/2- branching C4H07_RS10705 a (3R)-3- II: fabF phosphoglycerate phosphate superoxide arg ketoacyl-ACP synthase C4H07_RS14135 dehydrogenase: acetylornithine dehydrogenase/ FabI: fabI C4H07_RS03235 C4H07_RS01370 carboxylate [acyl- diphosphate C4H07_RS18900 C4H07_RS15820 cystathionine synthetase: synthetase: protein acquisition dismutase: arsenate lysine C4H07_RS18670 O-methyltransferase [+ 6 isozymes] [+ 5 isozymes] C4H07_RS07545 (glutathion-S[+- 5 isozymes] deacetylase: argE methoxy-6-polyprenyl- class III alcohol enoyl-ACP [+ 5 isozymes] reductase: UMP hydroxybutanoyl-[acp] ketoacyl-ACP synthase kinase: pgk III: C4H07_RS12260 [1-(2-amino-7-methyl-4-oxo- an odd numbered ω beta-lyase: metC a (3R,7Z,10Z,13Z,16Z C4H07_RS02235 C4H07_RS02235 enoyl-ACP a (3R,5Z)-3- GlgB: glgB ribonucleotide- carrier- lipoprotein selenate [+ 2 isozymes] C4H07_RS18900 reductase: [+ 6 isozymes] UbiG: ubiG -carboxy- (E)-2-(1H-indol-3-yl)- a ferrocytochrome a (2E)-hexadec-2-enoyl- a (2E)-hex-2-enoyl- 1,4-benzoquinol dehydrogenase: C4H07_RS13380 synthase III: decarboxylase: acyl-carrier protein a (7Z)-3-oxo-hexadec-7-enoyl-[acp] 7,8-dihydro-3H-pteridin- straight chain pyruvate ,19Z)-3-hydroxydocosa- yl)-4-hydroxy- acetate L-citrulline reductase FabI: reductase hydroxydodec- diphosphate reductase: CMP 3-hydroxyacyl- protein] HpnD: hpnD signal peptidase: sulfate a phosphate C4H07_RS11770 diphosphate AMP AMP diphosphate (9Z)-octadec- b [acp domain within [acp domain within methylase UbiE: ubiE C4H07_RS19380 Hyp starch C4H07_RS12260 presqualene C4H07_RS18915 6-yl)]ethyl diphosphate ubiquinol-10 1-thioacetohydroximate 1 2-nonenal C4H07_RS03235 FabI: fabI C4H07_RS04510 ACP dehydratase 3-phospho- C4H07_RS10200 monoester hydrogen peroxide [+ 2 isozymes] 2,3,4-saturated 7,10,13,16,19-pentaenoyl-[acp] 5-enoyl-[acp] phosphorylation a (7Z)-3-oxotetradec- synthase adenylyltransferase 5'-nucleotidase hydrogen arsenite agmatine 9-enoyl-CoA a fatty acid synthase] a fatty acid synthase] a (2E)-dec- dGDP FGAR diphosphate fatty acyl CoA MQH 2-methylbutanal C4H07_RS04515 FabZ: fabZ 7-enoyl-[acp] an (11Z)-3-II: fabF D-glycerate subunit CysD: cysD peroxide 2 a gondoyl-[acp] CMP an (S-diacyl-sn- adenosine 5'- SurE: 2-enoyl-[acp] oxooctadec- squalene a lipoprotein urea cycle GTP phosphoribosylformylglycinamidine (d)CMP kinase: SDR family glyceryl)-L-cysteinyl- phosphoselenate C4H07_RS10025 catalase: glutathione peroxidase: catalase: dADP a (2E)-but-2-enoyl-[acp] 11-enoyl-[acp] synthase 2,3- histidine signal peptide synthase: purL C4H07_RS15055 oxidoreductase: [apolipoprotein] phosphate C4H07_RS19890 C4H07_RS13275 C4H07_RS19890 nucleoside- SDR family HpnC: diphosphoglycerate- phosphatase an N 6 -L- 3-oxo-2-(cis-2'-pentenyl) a (9Z)-3- a glucosylated CDP enoyl-ACP C4H07_RS01370 arg a reduced (E)-1-(L-cystein-S-yl)-N- a [protein]- a (3R)-3- a (3R)-3- a ribonucleoside a (3R)-3- hpnC dependent family protein: arsenite 37 a 3-oxohexacosanoyl- indole-3-glycol (2S, 3S)-3- diphosphate kinase: nucleoside- FGAM oxidoreductase: apolipoprotein N- hydroxyl radical O a (3Z)-dodec-3-enoyl-[acp] a malonyl-[acp] threonylcarbamoyladenine electron-transfer ubiquinone-6 3-demethylubiquinol-9 linoleate hydroxy-ω-(methylsulfanyl) a type IV prepilin -cyclopentane-1-(3R- FAD hydroxytetradecanoyl- hydroxybutanoyl- a behenoyl-[acp] oxooctacos- hydroxyicosanoyl- glycogenin reductase [+ 5 isozymes] phosphoglycerate C4H07_RS12500 O H O 2 L-threonine [acp] diphosphate methylaspartate C4H07_RS10705 diphosphate kinase: nucleoside- C4H07_RS14135 acyltransferase: lnt 2 2 in tRNA long-chain fatty hydroxyhexanoyl)-CoA FAD:protein FMN 9-enoyl-[acp] 1,4-alpha- a (3R,7Z)-3- presqualene beta-ketoacyl-[acyl-carrier- flavoprotein electron transfer bifunctional 2-polyprenyl-6- heptan-1-iminecystathionine prepilin peptidase: [acp domain within SDR family [acp domain within ribonucleotide- S-(hydroxymethyl) enoyl-ACP SDR family [acp] 3-hydroxyacyl- phosphoribosylformylglycinamidine diphosphate FabI: fabI mutase: gpmA an N-acyl-(S-diacyl- selenite tRNA 3-hydroxyacyl-CoA methylaspartate glucan C4H07_RS10705 hydroxytetradec- [+ 5 isozymes] diphosphate 2,3- arginase: protein] synthase II: fabF hydroxyphenol methylase/ acid--CoA ligase: C4H07_RS19720 transferase: a fatty acid synthase] oxidoreductase: a fatty acid synthase] diphosphate glutathione reductase oxidoreductase: enoyl-ACP a peptide argininosuccinate flavoprotein- beta-lyase: metC acyl-CoA acyl-CoA ammonia-lyase: ACP cyclo-ligase: C4H07_RS18650 kinase: a (3R,11Z)-3- synthase histidine diphosphoglycerate- sn-glyceryl)-L- C4H07_RS07635 ammonium threonylcarbamoyladenosine 3-demethylubiquinol 3- C4H07_RS05530 dehydrogenase: C4H07_RS13750 reductase: dehydrogenase/ branching 7-enoyl-[acp] lyase: argH ketoacyl-ACP synthase ubiquinone cystathionine prepilin peptidase: synthetase: C4H07_RS14135 synthetase: FabI: fabI C4H07_RS03415 C4H07_RS14135 dehydratase dGTP dATP C4H07_RS10705 reductase FabI: hydroxyoctadec- phosphatase dependent cysteinyl-[lipoprotein] arginase: dehydratase: C4H07_RS03065 C4H07_RS08935 protein HpnD: hpnD 6 oxidoreductase: O-methyltransferase [+ 6 isozymes] C4H07_RS04510 class III alcohol FabZ: fabZ AIR C4H07_RS03235 III: C4H07_RS12260 a cyclic N -L- beta-lyase: metC C4H07_RS09225 3-oxo-2-(cis-2'-pentenyl) a [protein]-FMN- C4H07_RS02235 a (3R)-3-[+ 5 isozymes] C4H07_RS02235 enoyl-ACP methylaspartate a cis-delta9-3-[+ 5 isozymes] CTP 11-enoyl-[acp] family protein: phosphoglycerate rocF carbamoyl- UbiG: ubiG (E)-ω-(methylsulfanyl) a cleaved type AMP a (2E)-tetradec-2-enoyl- a (2E)-but-2-enoyl- C4H07_RS04515 dehydrogenase: a (2E)-icos- GlgB: glgB acyl-carrier protein a (5Z)-3-oxo-tetradec-5-enoyl-[acp] threonylcarbamoyladenosine C4H07_RS12055an oxidized pyruvate a peptide -cyclopentane-1-(3- L-threonine hydroxyhexacosanoyl- a 2'- reductase FabI: hydroxyC28:1- 3-hydroxyacyl- squalene C4H07_RS12500 mutase: gpmA phosphate AMP diphosphate linoleoyl-CoA heptyl-thiohydroximate IV prepilin [acp domain within [acp domain within C4H07_RS19380 ammonia-lyase: 2-enoyl-[acp] a glycogen selenodiglutathione 37 in tRNA + ubiquinol-9 oxohexanoyl)-CoA C4H07_RS03235 a butanoyl-[acp] ACP L-arginino- H ubiquinol-6 electron-transfer [acp] a fatty acid synthase] deoxyribonucleoside indole-3- C4H07_RS15445 [acp] a (2E,7Z)-tetradeca- L-ornithine synthase a fatty acid synthase] a (2E)-docos- 2,7-dienoyl-[acp] dehydratase 2-phospho- N 6 -L-threonylcarbamoyladenosine 37 succinate flavoprotein 5'-diphosphate glycol aldehyde mesaconate ketoacyl-ACP large 2-enoyl-[acp] FabZ: fabZ D-glycerate -modified tRNA biosynthesis subunit: carB synthase III: enoyl-ACP a (2E,11Z)- Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis (3S)-2,3- C4H07_RS12260 reductase FabI: octadeca-2,11- epoxy-2,3- phosphopyruvate carbamoyl C4H07_RS03235 thr glutathioselenol L-alanyl-γ-D-glutamyl-meso- (E)-1-(L-cystein-S-yl)-N- 3-oxo-2-(cis-2'-pentenyl) a (3R)-3- (11Z)-(S)-3- a (2E,7Z)- (2Z,4E)-2- an (11Z)-3- a (3R,6Z)-3- beta-ketoacyl- dienoyl-[acp] dihydrosqualene hydratase: phosphate octanoate sn-glycerol (3S)-citryl-CoA a 3-oxotetracosanoyl- + α-amylose flavin biosynthesis I (bacteria and plants) threonylcarbamoyl- ornithine a (7Z)-hexadec-7-enoyl-[acp] a malonyl-[acp] 3-demethylubiquinol-7 hydroxy-ω-(methylsulfanyl) a palmitoyl-[acp] -cyclopentane-1-(3R- hydroxyoctadecanoyl- NAD NADPH hydroxyhexadec- hexadeca-2,7- hydroxyhexa- oxo-icos-11- hydroxyoctadec- superpathway of tetrahydrofolate biosynthesis [acyl-carrier- enoyl-ACP enoyl-ACP C4H07_RS11970 dGTP 2,6-diaminopimeloyl-D-alanine [acp] IMP ubiquinol-8 biosynthesis superpathay of heme b superpathway of coenzyme A biosynthesis I (bacteria) superpathway of pyridoxal 5'-phosphate biosynthesis and salvage molybdenum cofactor biosynthesis carbamoyltransferase: long-chain fatty pentan-1-imine 3-phosphate hydroxyoctanoyl)-CoA citryl-CoA lyase: [acp domain within enoyl-[acp] 6-enoyl-[acp] 1,4-alpha- reductase reductase FabI: AMP synthase: argininosuccinate beta-ketoacyl-[acyl-carrier- muramoyltetrapeptide bifunctional 2-polyprenyl-6- cystathionine glycerol-3- SDR family NAD(P)(+) 11-enoyl-CoA dienoyl-[acp]enoyl-ACP 2,4-dienedioate4-oxalocrotonate SDR family 3-hydroxyacyl- (prokaryotic) biosynthesis from glutamate protein] argF deoxyguanosinetriphosphate 3-hydroxyacyl-CoA 5'-3'- enoyl-CoA glucan C4H07_RS03235 phosphoenol C4H07_RS07620 synthase: argG protein] synthase II: fabF carboxypeptidase: hydroxyphenol methylase/ acid--CoA ligase: C4H07_RS02475 a fatty acid synthase] oxidoreductase: transhydrogenase reductase FabI: oxidoreductase: 3-methyl-2- a 5,10- D-erythrose synthase II: fabF FabI: fabI triphosphohydrolase: beta-lyase: metC phosphate 1-O- dehydrogenase: acyl-CoA deoxyribonucleotidase: hydratase tautomerase: ACP all-trans- threonylcarbamoyl- C4H07_RS08485 3-demethylubiquinol 3- C4H07_RS15820 citryl-CoA lyase: (Re/Si-specific): C4H07_RS03235 C4H07_RS01370 branching GTP oxobutanoate methylenetetrahydrofolate 4-phosphate enoyl-ACP pyruvate L-citrulline ketoacyl-ACP synthase C4H07_RS01005 cystathionine acyltransferase synthetase: C4H07_RS14135 family protein: C4H07_RS01820 dehydratase 4-hydroxybenzoate octaprenyl GTP glu ATP a (7Z)-tetradec- biotin-carboxyl carrier hydrogen selenide O-methyltransferase [+ 6 isozymes] C4H07_RS08935 C4H07_RS13035 C4H07_RS04945 C4H07_RS18395 protein a 3-oxohexanoyl-[acp] reductase AMP synthase: III: C4H07_RS12260 LD-carboxypeptidase: beta-lyase: metC PlsY:1-palmitoyl- plsY 3-oxo-2-(cis-2'-pentenyl) C4H07_RS02235 a (3R)-3-[+ 5 isozymes] C4H07_RS18325 enoyl-ACP 4-oxalocrotonate a (3R,11Z)-3-[+ 5 isozymes] a (2E,6Z)-FabZ: fabZ glutamate-- 3-methyl-2-oxobutanoate GTP 7-enoyl-[acp] protein assembly 2'-deoxyguanosine triphosphate UbiG: ubiG ω a (2E)-octadec-2-enoyl- C4H07_RS04955 [+ 2 isozymes] GlgB: glgB bifunctional 4-hydroxybenzoatediphosphate FabI: fabI C4H07_RS07770 C4H07_RS13975 (E)- -(methylsulfanyl) -cyclopentane-1-(3- acetyl-CoA oxaloacetate reductase GTP tRNA ligase: hydroxymethyltransferase: phosphoenolpyruvate pyruvate (L-threonylcarbamoyl) oleate β-oxidation Fatty Acid and Lipid Degradation acyl-carrier protein a (9Z)-3-oxo-octadec-9-enoyl-[acp] diphosphate AMP octanoyl-CoA pyruvate acyl-carrier protein sn-glycerol hydroxytetracosanoyl- [+ 7 isozymes] tautomerase: hydroxy-icos- octadecadienoyl- octaprenyltransferase: ketoacyl-ACP a [biotin carboxyl- L-alanyl-γ-D-glutamyl- pentyl-thiohydroximate [acp domain within NADP + inosine (2E,11Z)-hexadec- amylopectin 3,4-dihydroxy- cys SDR family synthase: ppsA kinase: pyk adenylate androstenedione degradation D-ala ubiquinol-7 3-phosphate oxooctanoyl)-CoA [acp] NADH FabI: fabI C4H07_RS11475 11-enoyl-[acp] [acp] C4H07_RS00870 cyclohydrolase C4H07_RS04545 panB 4-phospho- GTP 3',8- synthase III: a cis- carrier protein]-L-lysine meso-diaminopimelate a fatty acid synthase] 2-butanone- 3-octaprenyl-4- an L-glutamyl- oxidoreductase: 6 2,11-dienoyl-CoA a (7Z)-hexadec- (3E)-2-oxohex- I FolE2: asp vaccenoyl-[acp] N -L- Glu D-erythronate cyclase C4H07_RS12260 oleate 7-enoyl-[acp] 3-enedioate 4-phosphate hydroxybenzoate [tRNA ] 2-dehydropantoate a carboxy- C4H07_RS14135 biotin--[acetyl-CoA- threonylcarbamoyladenine Aldehyde Degradation androst-4-ene-3,17-dione C4H07_RS05600 erythronate- MoaA: carboxylase] ligase: pyruvate synthase/GTP 4-hydroxy-3- 7,8- glutamyl-tRNA adenylated [+ 5 isozymes] beta-ketoacyl- synthase: tsaD aspartate 1- moaA long-chain fatty cyclohydrolase II: polyprenylbenzoate reductase: 2-dehydropantoate 4-phosphate [small subunit of [acyl-carrier- C4H07_RS00510 an N 6 -L- methylglyoxal degradation I dihydroneopterin decarboxylase: an [L-cysteine (8S)-3',8-cyclo-7,8- a (3R)-3- a [biotin carboxyl- acid--CoA ligase: (11Z)-3- 3-oxo-2-(cis-2'-pentenyl) a 3,5,7,9,11,13,15- DNA with adenine:7,8- 2-reductase: dehydrogenase: 37 a [DNA]-3'- a 5'-phospho- (E)-1-(L-cystein-S-yl)-N- (2E,7Z)- a (3R)-3- C4H07_RS16940 decarboxylase: ubiD 3'-triphosphate C4H07_RS02505 C4H07_RS10525 molybdopterin desulfurase]-S- protein] threonylcarbamoyladenine C4H07_RS05530 isobutanoate quinoxaline-2- + a 3-oxoacyl-CoA a holo [BryU acyl- a cis,cis-delta5,17-3- sn-glycerol a protein with 2,5-diamino-6- serA dihydroguanosine hydroxyhexanoyl-[acp] carrier protein]-N a glutaryl-[acp] methyl ester a malonyl-[acp] aryl-carrier protein 3-demethylubiquinol-6 NAD hydroxy-ω-(methylsulfanyl) oxohexadecenoyl- -cyclopentane-1-(3R- hepta-oxo- tetradecenoyl-CoA dihydro-8- a palmitoyl-[acp] D-arginine hydroxydocosanoyl- C4H07_RS12995 synthase] sulfanyl-L-cysteine synthase cis-vaccenate in tRNA carboxyl adenylate hydroxyl [DNA] carrier protein] hydroxyC36:2[acp] 3-phosphate a disulfide bond (5-phospho-D- (S)-4-amino-5- 5'-triphosphate 6 -biotinyl-L-lysine methylglyoxal [+ 6 isozymes] acetyl-CoA synthetase: bifunctional 2-polyprenyl-6- NAD- nonan-1-imine CoA hydroxybutanoyl)-CoA acetyl-CoA C- hexadecanoyl-[PKS-acp] enoyl-CoA oxoguanine mismatch [acp] glycerol-3- 2-octaprenylphenol β-alanine (3R)-3-hydroxy-2-oxo- 3-hydroxyacyl- II: fabF androsta-1,4-diene-3,17-dione ketoacyl-ACP synthase acyl carrier protein: cystathionine acetyl-CoA C- aldo/keto SDR family A/G-specific enoyl-ACP D-amino acid 3-hydroxyacyl- protein- oxopentanoate (R)-pantoate cyclic pyranopterin lactoylglutathione C4H07_RS02270 hydroxyphenol methylase/ dependent 3-hydroxyacyl-CoA acyltransferase: ACP S- hydratase ribosylamino) 4 phosphooxybutanoate ACP dehydratase oleoyl-CoA III: C4H07_RS12260 C4H07_RS04475 beta-lyase: metC acyltransferase: reductase: oxidoreductase: adenine reductase dehydrogenase: ACP phosphate 1-O- disulfide monophosphate a (9Z)-3-oxohexadec- lyase: gloA dehydrogenase: C4H07_RS17645 malonyltransferase: family protein: pyrimidin- 7,8- glutamate-1- FabZ: fabZ beta-ketoacyl-[acyl-carrier- [+ 3 isozymes] acyl carrier 3-demethylubiquinol 3- DNA ligase C4H07_RS13210 C4H07_RS14135 glycosylase: FabI: fabI dehydratase acyltransferase reductase 3-phosphoserine/ synthase 9-enoyl-[acp] (R)-S- cystathionine C4H07_RS17645 C4H07_RS08935 fabD C4H07_RS08565 4(3H)-one dihydroneopterin semialdehyde acyl-CoA O-methyltransferase LigA: ligA 3-oxo-2-(cis-2'-pentenyl) [+ 3 isozymes] C4H07_RS18325 PlsY: plsY pantoate--beta- phosphohydroxythreonine a thiocarboxylated a [biotin carboxyl- lactoylglutathione protein] synthase II: fabF protein: acpP beta-lyase: metC [+ 3 isozymes] 9-hydroxy-3,5,7,11,13,15-[+ 2 isozymes] a malonyl- a cis,cis-[+ 5 isozymes] mutY enoyl-ACP D-amino acid FabZ: fabZ 1-arachidinoyl- a protein withDsbD: dsbD 3-(all-trans 3'-phosphate 2,1-aminomutase: MoaC: moaC a (2E)-hex-2-enoyl-[acp] SDR family isobutanoyl-CoA AMP diphosphate a quinoxaline-2- UbiG: ubiG ω (9Z)- acetyl-CoA [+ 7 isozymes] a (2E)-docos- D-ribulose bifunctional alanine ligase: transaminase: serC [small subunit of cyclic carrier-protein dimer]- dehydrogenase: 9α-hydroxyandrosta- acyl-carrier protein a 3-oxopimeloyl-[acp] methyl ester pyruvate (E)- -(methylsulfanyl) acetyl-CoA -cyclopentane-1-(3- an acyl-CoA hexaoxohexadecanoyl- [BryU acyl- delta5,17-3- an apurinic site reductase FabI: sn-glycerol reduced L- C4H07_RS18295 hydroxyacylglutathione AMP carboxyl-[aryl- NMN AMP [DNA] (S)-3-hydroxy-(7Z) adenine dehydrogenase: diaminohydroxyphosphoribosylaminopyrimidine -octaprenyl) D-glyceraldehyde oxidoreductase: 6 C4H07_RS17655 ubiquinol-6 nonyl-thiohydroximate tetradecenoyl-CoA oxobutanoyl)-CoA carrier protein] within DNA C4H07_RS03235 2-enoyl-[acp] 3-phosphate 5-phosphate chorismate C4H07_RS19735 4-phosphooxy- molybdopterin pyranopterin N -biotinyl-L-lysine 1,4-diene-3,17-dione [PKS-acp] oxo-C36:2-[acp] -tetradecenoyl-CoA C4H07_RS10535 cysteine residues deaminase/5-amino-6-(5-phosphoribosylamino) benzene-1,2-diol pyruvate enoyl-ACP C4H07_RS14135 hydrolase: gloB carrier protein] a (2E)-hexadec- 5-guanidino-2- 5-aminolevulinate 3-phosphate synthase] phosphate acetyl-CoA acetyl-CoA [+ 12 isozymes] 3,4-dihydroxy- bifunctional 2- aminodeoxychorismate/ L-threonine reductase 2-enoyl-[acp] uracil reductase RibD: ribD 7,8- thiamine diphosphate [+ 5 isozymes] carboxylase carboxylase (2E,9Z)- oxopentanoate 2-butanone- 5-amino-6-(5- polyprenyl-6- anthranilate synthase (R)-pantothenate 1-deoxy-D-xylulose- 4-hydroxythreonine- FabI: fabI a (3R,9Z)-3- (R)-lactate dihydroneopterin porphobilinogen molybdopterin biosynthesis I (E. coli) carboxyltransferase biotin octadecenoyl-CoA 4-phosphate phospho-D- hydroxyphenol component II: 5-phosphate 4-phosphate enoyl-ACP hydroxyhexadec- 3-hydroxy-9,10- synthase: hemB type III synthase: subunit alpha: carboxylase synthase: ribosylamino)uracil dihydroneopterin synthase: dehydrogenase enoyl-CoA secoandrosta-1,3,5(10) (3R)-3- methylase/3- C4H07_RS02995 C4H07_RS06035 reductase FabI: 9-enoyl-[acp] core 2,3,6- (E)-1-(L-cystein-S-yl)-N- 3-oxomyristoyl- a cytidine 1402 a cis,cis-delta9,21- a cis,cis- C4H07_RS01345 pantothenate HMP-PP C4H07_RS08895 subunit: accC hydratase 7-hydroxylaurate a peptidoglycan dimer (generic) glutathione S-(4-oxo-2-methylpentan- a holo [BryP acyl- citrate sn-glycerol bifunctional demethylubiquinol 3- aldolase: folB C4H07_RS05595 PdxA: pdxA C4H07_RS03235 -triene-9,17-dione an oleoyl-[acp] a malonyl-[acp] an L-1- oligosaccharide- hydroxy-ω-(methylsulfanyl) thr roseoflavin 3-hydroxyC40:2- a hexanoyl-[acp] delta19,37- a protein hydroxypentanoyl- aminodeoxychorismate porphobilinogen kinase: thiamine family protein: trichlorohydroquinone 2-yl)-L-cysteine CoA in 16S rRNA carrier protein] ATP 3-phosphate diaminohydroxyphosphoribosylaminopyrimidine O-methyltransferase 1-deoxy-D- 3-amino-1- acetyl-CoA acetyl-CoA lipid A (E. coli long-chain fatty lytic transglycosylase glutathione S- acetyl-CoA C- 16S rRNA 5'-phosphate [acp] Fe/S-dependent 3-hydroxy- glycerol-3- CoA bifunctional 6-(hydroxymethyl) synthase component C4H07_RS00505 phosphate pyruvate beta-ketoacyl-[acyl-carrier- phosphatidylethanolamine hexan-1-iminecystathionine cystathionine threonine ammonia- SDR family enoyl-ACP ATP-dependent acetoacetyl- deaminase/5-amino-6-(5-phosphoribosylamino) xylulose 5- hydroxyacetone molybdopterin a hexanoyl-[acp] carboxylase carboxylase C4H07_RS18325 acid--CoA ligase: domain-containing transferase: acyltransferase: (cytidine(1402)-2'-O) ACP S- bifunctional 2-methylisocitrate C56:2-[acp]SDR family 3,4-dihydroxy- UbiG: ubiG -7,8-dihydropterin I: C4H07_RS03100 hydroxymethylbilane synthase: protein] synthase II: fabF phosphoethanolamineK-12 core type) beta-lyase: metC beta-lyase: metC oxidoreductase: reductase Clp protease phosphate 1-O- CoA uracil reductase RibD: ribD (R)-4'- 1-phosphate pyridoxine carboxyltransferase biotin [+ 7 isozymes] protein: C4H07_RS00400 lyase: C4H07_RS15400 malonyltransferase: 2-butanone- 2-methoxy- synthase: hemC phosphate a (2E,9Z)-hexadeca- 3,4-dihydroxy-9,10- transferase: C4H07_RS15820 C4H07_RS17645 -methyltransferase: riboflavin kinase/ C4H07_RS14135 dehydratase FabI: fabI oxidoreductase: proteolytic subunit: acyltransferase 5-amino-6-(5- 2-amino-4-hydroxy-6- 4-amino-4- phosphopantothenate molybdopterin C4H07_RS18290 subunit beta: carboxylase ketoacyl-ACP synthase cystathionine cystathionine threonine ammonia- fabD reductase: 4-phosphate 6-(all-trans- thiamine ketoacyl-ACP 2,9-dienoyl-[acp] (S)-3-hydroxy-(9Z) lipid A-core- C4H07_RS11685 [+ 6 isozymes] C4H07_RS03970 [+ 5 isozymes] [+ 3 isozymes] rsmI FAD synthetase: AcnD: acnD C4H07_RS14135 PlsY: plsY phospho-D- hydroxymethyldihydropteridine deoxychorismate pyridoxamine adenylyltransferase: secoandrosta-1,3,5(10) III: C4H07_RS12260 a 1,2-diacyl- 2,6-dichloro-3- beta-lyase: metC beta-lyase: metC a 2'-O- a malonyl- a cis,cis-[+ 5 isozymes] enoyl-ACP C4H07_RS10320 1-oleoyl-sn phbB octaprenyl)phenol bifunctional pyridoxine 5'- synthase III: C4H07_RS17495 subunit: accC -octadecenoyl-CoA phosphoethanolamine [+ 2 isozymes] ω lyase, biosynthetic: ilvA synthase/GTP preuroporphyrinogen phosphate enoyl-ACP -triene-9,17-dione (E)- -(methylsulfanyl) 4-methyl-4- acetyl-CoA lauroyl-CoA 1402 C4H07_RS10210 [+ 3 isozymes] a cis,cis-[+ 5 isozymes] 3-oxopentanoyl- ribitylamino)uracil diphosphokinase: pyridoxine/ C4H07_RS14725 a [carboxyl-carrier acyl-carrier protein an (11Z)-3-oxo-icos-11-enoyl-[acp] sn-glycerol 7-hydroxylauroyl- (glutathion-S-yl) pyruvate pyruvate 2-oxobutanoate methylcytidine [BryP acyl- roseoflavin adenine delta9,21-3- reductase FabI: a peptide -glycerol 3- cyclohydrolase II: phosphopantothenoylcysteine phosphate pyridoxine/ C4H07_RS12260 3-hydroxyacyl-CoA (hep I) AMP diphosphate GlcNAc-1,6-anhydro- hexyl-thiohydroximate sulfanylpentan-2-one delta19,37-3- CoA pyridoxal/ molybdopterin thiamine- reductase FabI: 6 CoA a lipid II -hydroquinone in 16S rRNA carrier protein] dinucleotide D-threo-isocitrate C4H07_RS03235 phosphate C4H07_RS18670 uroporphyrinogen- synthase: protein dimer]-N - MurNAc-pentapeptide oxo-C40:2-[acp] C4H07_RS16940 (7,8-dihydropterin- decarboxylase/ pyridoxamine pyridoxal/ adenine phosphate beta-ketoacyl- C4H07_RS03235 dehydrogenase: a (2E)-hex- oxo-C56:2-[acp] III synthase: pdxJ carboxybiotinyl-L-lysine 2-methoxy-6-all phosphopantothenate-- pyridoxamine kinase: thiL [acyl-carrier- C4H07_RS08935 2-enoyl-[acp] 1-deoxy-L- 6-yl)methyl 4-aminobenzoate C4H07_RS06965 kinase: pdxK dinucleotide enoyl-ACP (1E,2Z)-3-hydroxy- trans-octaprenyl- cysteine ligase CoaBC: coaBC kinase: pdxK molybdopterin protein] 3-oxo-(9Z)- glycero-tetrulose ARP diphosphate thiamine reductase 5,9,17-trioxo-4,5:9,10- 1,4-benzoquinol (R)-4'- molybdotransferase synthase II: fabF octadecenoyl-CoA 4-phosphate uroporphyrinogen-III pyridoxine pyridoxamine diphosphate FabI: fabI disecoandrosta-1 phosphopantothenoyl- an [amino group carrier protein]- 1402 a 3- UDP-N-acetyl- a cis,cis- (3R)-3- bifunctional dihydropteroate 5'-phosphate 5'-phosphate MoeA: acetyl-CoA C- (E)-1-(L-cystein-S-yl)-N- 1-chloro-2,4- 3-oxo-(5Z)- a cytidine a stearoyl-[acp (2E,5Z)- sn-glycerol sn-glycerol L-cysteine ornithine lipid (10),2-dien-4-oate succinyl-CoA acetoacetate 2-methylbutanoate γ S-(5-hydroxypentan- glutathione α 6,7-dimethyl-8- demethylmenaquinone synthase: folP uroporphyrinogen C4H07_RS06045 a 3-oxooctanoyl-[acp] a palmitoleoyl-[acp] a (5Z)-tetracos-5-enoyl-[acp] a malonyl-[acp] a decanoyl-[acp] C-terminal- -(L-glutamate 5- hydroxy-ω-(methylsulfanyl) dinitrobenzene dodecenoyl-CoA in 16S rRNA domain within a oxodocosanoyl- -D-glucosamine dodecenoyl-CoA Ins(1)P delta17,35-3- hydroxybutanoyl- biosynthesis acyltransferase: 3-yl)-L-cysteine UDP-N- 3-phosphate 3-phosphate ribityllumazine methyltransferase/2- decarboxylase: bifunctional ketoacyl-ACP synthase 3-oxoacid CoA-transferase acetyl-CoA beta-ketoacyl-[acyl-carrier- semialdehyde-2-yl)-L-glutamateN-acetyl-gamma- octan-1-imine glutathione S- acetyl-CoA C- 16S rRNA fatty acid synthase] [acp] SDR family enoyl-CoA inositol hydroxyC54:2- glycerol-3- glycerol-3- CoA pyridoxamine 5'- pyridoxamine 5'- pyridoxal molybdopterin C4H07_RS17645 cystathionine cystathionine acetoacetyl- synthase: methoxy-6-polyprenyl- 7,8- C4H07_RS02855 phosphopantothenoylcysteine SDR family subunit A: C4H07_RS18820 synthetase: transferase: acyltransferase: (cytosine(1402)-N(4) acyl-CoA acetylglucosamine hydratase [acp] SDR family phosphate 1-O- molybdotransferase [+ 3 isozymes] III: C4H07_RS12260 protein] synthase II: fabF glutamyl-phosphate beta-lyase: metC beta-lyase: metC oxidoreductase: monophosphatase: phosphate 1-O- CoA C4H07_RS16945 decarboxylase/ phosphate oxidase: phosphate oxidase: oxidoreductase: L-ornithine 3-oxoacid CoA-transferase C4H07_RS02270 C4H07_RS00400 C4H07_RS17645 synthetase: 2-epimerase (non- family protein: 1,4-benzoquinol dihydropteroate thiamine diphosphate phosphatidylglycerol 3-[(3aS,4S,7aS)-7a-methyl- beta-ketoacyl-[acyl-carrier- ketoacyl-ACP synthase reductase: )-methyltransferase C4H07_RS14135 C4H07_RS05515 oxidoreductase: acyltransferase acyltransferase reductase: coproporphyrinogen III C4H07_RS11120 C4H07_RS11120 pyridoxine/ MoeA: C4H07_RS14135 (2Z,4Z)-2-hydroxyhexa- cystathionine cystathionine C4H07_RS02235 hydrolyzing): methylase UbiE: ubiE phosphopantothenate-- subunit A: C4H07_RS10385 [+ 3 isozymes] [+ 5 isozymes] [+ 3 isozymes] 4 RsmH: rsmH C4H07_RS18325 C4H07_RS14135 PlsY: plsY bifunctional C4H07_RS12450 biosynthesis II (Bacillus) biosynthesis II (non-plastidic) (7Z)-hexadecenoyl-CoA 1,5-dioxo-octahydro-1H protein] synthase II: fabF III: C4H07_RS12260 an [amino group carrierC4H07_RS04635 protein]- beta-lyase: metC beta-lyase: metC an N - an [acyl carrier protein] a (3R)-3-[+ 5 isozymes] inositol 1-C16:0-α,ωPlsY:- plsY 1-palmitoyl- phbB 6-methoxy-3- cysteine ligase CoaBC: coaBC pyridoxamine pyridoxamine pyridoxal/ [+ 5 isozymes] 2,4-dienoate ω 2,4-dinitrophenyl- (3Z)-dec-3- C4H07_RS00470 a cis,cis- 6,7-dimethyl-8-(1- tetrahydrofolate oxygen-dependent MoO - palmitoleate -inden-4-yl]propanoate acetoacetyl-CoA succinate 2-methylbutanoyl- C-terminal-γ-(5-phospho- (E)- -(methylsulfanyl) acetyl-CoA methylcytidine 1402 domain within a UDP-N-acetyl-α- [+ 7 isozymes] monophosphatase: [+ 5 isozymes] dicarboxyl-2- sn-glycerol acetoacetyl-CoA 2 acyl-carrier protein a (7Z)-3-oxohexacos-7-enoyl-[acp] a 3-oxododecanoyl-[acp] pyruvate pyruvate 3-sulfanylpentan-1-ol enoyl-CoA hydroxydocosanoyl- methyl-2-all- 5'-phosphate 5'-phosphate pyridoxamine DHAP a lyso- acyl-CoA AMP diphosphate octyl-thiohydroximate S-glutathione (S)-3-hydroxy-(5Z) delta17,35-3- D-ribityl)lumazine synthase/ coproporphyrinogen molybdopterin HMP-PP a (3R)-3- acyl-CoA CoA L-glutamyl)-L-glutamate in 16S rRNA fatty acid synthase [acp] D-mannosamine C4H07_RS08855 lysophosphatidate 3-phosphate trans-octaprenyl- 4'-phosphopantetheine oxidase: pdxH oxidase: pdxH kinase: pdxK NAD(P)-dependent ornithine lipid dehydrogenase: -dodecenoyl-CoA oxo-C54:2-[acp] riboflavin synthase: dihydrofolate oxidase: hemF cofactor thiamine hydroxyoctanoyl-[acp] synthetase: myo-inositol 1,4-benzoquinol glycerol-3- C4H07_RS17655 C4H07_RS05175 synthase: folC pantetheine- phosphate 3-hydroxyacyl- (S)-4-hydroxy- C4H07_RS02235 protoporphyrinogen IX phosphate [+ 12 isozymes] 3-[(3aS,4S,7aS)-7a-methyl- 6,7-dimethyl-8- 7,8-dihydrofolate phosphate PLP synthase: 2-oxohexanoate ACP dehydratase dehydrogenase: adenosylcobalamin 10 C4H07_RS18290 (2E,7Z)- 1,5-dioxo-octahydro-1H- ribityllumazine thiamine salvage II monoglutamate adenylyltransferase: N -formyl-tetrahydrofolate biosynthesis FabZ: fabZ a 10- 1915 (Z)-1-(L-cystein-S β a myristoyl-[acp a 3- a cis,cis- 4-methyl-3- thiamine C4H07_RS02125 hexadecenoyl-CoA inden-4-yl]propanoyl-CoA α a pseudouridine -D-fructofuranose an L-aspartyl- synthase: salvage from cobalamin coaD NAD de novo biosynthesis adenosylcobinamide-GDP formyltetrahydrofolate- -linolenate glutathione methylmercury reduced riboflavin Ins(2)P oxoadipate- a (3Z)-docos-3-enoyl-[acp] a malonyl-[acp] an arachidoyl-[acp] in 23S rRNA -yl)-N-hydroxy-2- S-fenclorimyl-L-cysteine 1-phosphate acyl-carrier protein domain within a oxodocosanoyl- Asn delta15,33- his a protein 3-demethylubiquinol-8 I (from aspartate) phosphate sn-glycerol an ornithine lipid [tRNA ] C4H07_RS16945 4-amino-2-methyl-5- 3'-dephospho- salvage from cobinamide I a (2E)-oct-2-enoyl-[acp] enoyl-CoA 4a-carbinolamine long-chain fatty 23S rRNA phenylethan-1-imine glutathione S- fructose- fatty acid synthase] [acp] flavin reductase: 3-hydroxy enol-lactone cob(I)alamin a tetrahydrofolate 3-phosphate ketoacyl-ACP synthase beta-ketoacyl-[acyl-carrier- cystathionine cystathionine SDR family Asp-tRNA(Asn) inositol 3-oxoadipate pyrimidinemethanol CoA thiamine- hydratase/ 4a-hydroxytetrahydrobiopterin acid--CoA ligase: transferase: ACP S- acyl-CoA C4H07_RS03045 C52:2-[acp] L-histidine N(alpha) bifunctional 2- protoporphyrin IX III: C4H07_RS12260 protein] synthase II: fabF (pseudouridine(1915)- beta-lyase: metC beta-lyase: metC bisphosphate oxidoreductase: /Glu-tRNA(Gln) monophosphatase: SDR family endopeptidase La: enol- riboflavin asp cob(II)inamide phosphate enoyl-ACP glycerol-3- isomerase 1-propanal pyruvate 5-hydroxy-3-[(3aS,4S dehydratase: C4H07_RS01755 C4H07_RS00400 malonyltransferase: synthetase: -methyltransferase: hydroxymethylpyrimidine/ polyprenyl-6- a 7,8-dihydrofolate dephospho- beta-ketoacyl-[acyl-carrier- ketoacyl-ACP synthase N(3))-methyltransferase aldolase class II: C4H07_RS14135 amidotransferase: nitrite/sulfite C4H07_RS05515 oxidoreductase: C4H07_RS10330 lactonase: cob(I)yrinic acid kinase: thiL reductase phosphate 1-O- family protein: C4H07_RS16130 cystathionine cystathionine fabD C4H07_RS02235 egtD phosphomethylpyrimidine ferrochelatase: CoA kinase: L-aspartate ,5R,7aS)-7a-methyl-1,5- [+ 6 isozymes] 3 RlmH: rlmH [+ 5 isozymes] C4H07_RS07575 reductase: C4H07_RS14135 bifunctional hydroxyphenol protein] synthase II: fabF 10 III: C4H07_RS12260 an N - beta-lyase: metC a 3-oxohexadecanoyl- [+ 5 isozymes] gatC gatA gatB inositol pcaD dihydrofolate cob(II)alamin oxidase: a,c-diamide thiamine FabI: fabI acyltransferase C4H07_RS02285 dioxo-octahydro-1H- an N - beta-lyase: metC methylmercury- a (3R)-3- an L-asparaginyl- riboflavin kinase/ kinase: C4H07_RS18285 methylase/3- C4H07_RS07145 C4H07_RS19715 methionine 1915 (Z)-2-phenyl-1- 6-chloro-2-phenyl- D-glyceraldehyde DHAP C4H07_RS16500 a cis,cis-[+ 5 isozymes] 4-methyl-3- PlsY: plsY long-chain fatty acyl-carrier protein a (5Z)-3-oxotetracos-5-enoyl-[acp] formyldihydrofolate a 3-oxodocosanoyl-[acp] methylpseudouridine a malonyl-[acp] [acp domain within hydroxydocosanoyl- Asn monophosphatase: hercynine a peptide reductase: C4H07_RS11850 adenosyltransferase: diphosphate inden-4-yl]propanoyl-CoA AMP diphosphate α-linolenoyl-CoA pyruvate pyruvate S-glutatione [tRNA ] delta15,33-3- oxoadipate FAD synthetase: bifunctional demethylubiquinol 3- synthase: metH enoyl-ACP a 1-acyl-sn acid activation [+ 7 isozymes] in 23S rRNA thioacetohydroximate 4-sulfanylpyrimidine a fatty acid synthase] riboflavin C4H07_RS08855 C4H07_RS03535 cob(I)yrinic acid protoheme coenzyme A 2-iminosuccinate [corrinoid C4H07_RS04120 [acp] C4H07_RS10210 hydroxymethylpyrimidine O-methyltransferase reductase FabI: -glycerol 3- (S)-3-hydroxy-(7Z) oxo-C52:2-[acp] a,c-diamide adenosyltranferase]- a long-chain propanoyl-CoA myo-inositol kinase/ UbiG: ubiG C4H07_RS03235 phosphate -hexadecenoyl-CoA a tetrahydrofolate adenosyltransferase: cob(II)inamide fatty acid FMN phosphomethylpyrimidine dihydrofolate 1-acyl-sn-glycerol- long-chain fatty 3-hydroxyacyl-CoA (2E)-3-[(3aS,4S,5R,7aS) C4H07_RS04120 an octanoyl-[acp] kinase: thiD ubiquinol-8 cob(II)alamin- reductase: menaquinol-9 biosynthesis 3-phosphate acid--CoA ligase: dehydrogenase: -5-hydroxy-7a-methyl-1- bifunctional core 3-oxopentanoyl- an N-terminal- a (3R)-3-hydroxyacyl- a dodecanoyl-[acp a 3-oxoacyl-[acp a guanine 9 a uridine 38- a cis,cis- 2-pyrone-4,6- C4H07_RS03535 acyltransferase: C4H07_RS08935 oxo-octahydro-1H-inden- 1-methyl-dAMP 2-oxoglutarate S-(1-hydroxyhexan- L(or D)-O- squalene riboflavin kinase/ [corrinoid lipoate biosynthesis quinolinate C4H07_RS01755 a (4Z)-hexadec-4-enoyl-[acp] a malonyl-[acp] an L-1- oligosaccharide- a malonyl-[acp] L-methionyl-L- [acp domain within domain within a domain within a DHAP delta11,29- HMP-P serine glycine cleavage [corrinoid ketoacyl-ACP ATP cob(II)inamide adenine PRPP CoA in tRNA 40 in tRNA dicarboxylate adenosyltranferase] C4H07_RS18255 [+ 6 isozymes] 3-oxo-(7Z)- 4-yl]prop-2-enoyl-CoA DNA oxidative 3-yl)-L-cysteine acetyl-CoA C- seryl-[protein] NAD(P)-dependent phosphoserine squalene FAD synthetase: and incorporation I demethylmenaquinol-9 synthase III: a long-chain ketoacyl-ACP synthase phosphatidylethanolamine lipid A (E. coli beta-ketoacyl-[acyl-carrier- cystathionine type I methionyl a fatty acid synthase] fatty acid synthase] fatty acid synthase] tRNA RluA family 3-hydroxy 2-pyrone-4,6- menaquinol-6 biosynthesis a 7,8-dihydrofolate hydroxymethyltransferase: systema 5-methyltetrahydrofolateprotein carboxylating adenosyltranferase]- hexadecenoyl-CoA adenine acyl-CoA acyl-CoA acyl-CoA phosphoserine synthase C4H07_RS10210 bifunctional bifunctional C4H07_RS12260 1-acyl-sn-glycerol- acyl-CoA III: C4H07_RS12260 phosphoethanolamineK-12 core type) cob(I)yrinic acid protein] synthase II: fabF demethylase acyltransferase: aminopeptidase: (guanosine(37)-N1) pseudouridine glycerol-3- C48:2-[acp]SDR family dicarboxylate C4H07_RS04675 GcvH: gcvH nicotinate- cob(I)inamide phosphoribosyltransferase: beta-lyase: metC synthetase: synthetase: synthetase: phosphatase bifunctional 3-phosphate acetyl-CoA C- transferase: a,c-diamide AlkB: alkB C4H07_RS17645 map -methyltransferase synthase: phosphate oxidoreductase: hydrolase: HpnC: hydroxymethylpyrimidine an octanoyl-[acp] nucleotide cob(I)yrinic acid demethylmenaquinone beta-ketoacyl- beta-ketoacyl-[acyl-carrier- ketoacyl-ACP synthase C4H07_RS18540 cystathionine FAD demethylmenaquinol-6 acyltransferase: acyltransferase: adenosyltransferase: [+ 3 isozymes] an N-terminal C4H07_RS02235 C4H07_RS02235 C4H07_RS02235 TrmD: trmD C4H07_RS14075 dehydrogenase: C4H07_RS14135 C4H07_RS14015 SerB: serB hpnC kinase/ cob(I)alamin- methylenetetrahydrofolate methyltransferase/2- 3-[(3aS,4S,5R,7aS)-5- protein] synthase II: fabF lipid A-core- C4H07_RS11685a 1,2-diacyl- III: C4H07_RS12260 a trans-2,3-dehydroacyl- a (3R)-3-hydroxyacyl- an N 1 - (1E)-4-oxobut- lipoyl(octanoyl) thymidylate diphosphorylase: a,c-diamide [acyl-carrier- AMP succinate formaldehyde dAMP beta-lyase: metC met a 3-oxotetradecanoyl- presqualene phosphomethylpyrimidine bifunctional [corrinoid dehydrogenase/ methoxy-6-polyprenyl- C4H07_RS00195 C4H07_RS17645 hydroxy-7a-methyl-1-oxo- C4H07_RS04120 propanoyl-CoA acetyl-CoA L-seryl-[protein] 9 [+ 2 isozymes] C4H07_RS02125 a cis,cis-[+ 5 isozymes] 5-(2-hydroxyethyl) transferase adenosyltransferase: protein] acyl-carrier protein a (6Z)-3-oxooctadec-6-enoyl-[acp] pyrophosphoethanolamine sn-glycerol a 3-oxodocosanoyl-[acp] [acp domain within [acp domain within [acp domain within methylguanine 38- 1-ene-1,2,4- serine synthase: C4H07_RS00655 a 1,2-diacyl- triphosphate adenosylcobinamide pyruvate 3-sulfanylhexan-1-ol a pseudouridine delta11,29-3- diphosphate kinase: thiD demethylmenaquinone adenosyltranferase] methenyltetrahydrofolate 1,4-benzoquinol [+ 3 isozymes] octahydro-1H-inden-4-yl]- a fatty acid synthase] a fatty acid synthase] in tRNA sn-glycerol tricarboxylate -4-methylthiazole a [lipoyl-carrier protein]LipB: lipB C4H07_RS03540 C4H07_RS04120 synthase II: fabF sn-glycerol a fatty acid synthase] 40 in tRNA methyltransferase/2- cob(I)yrinic acid cyclohydrolase FolD: folD NaMN methylase UbiE: ubiE 3-hydroxypropanoyl-CoA 3-phosphate oxo-C48:2-[acp] hydroxymethylpyrimidine/ N 6 -octanoyl-L-lysine a (6S)-5- 3-phosphate (5Z)-tetradecenoyl-CoA 3-hydroxyacyl-CoA methoxy-6-polyprenyl- a,c-diamide bifunctional adenosylcobinamide menaquinol-9 a 3-oxodecanoyl-[acp] NAD salvage pathway III phosphomethylpyrimidine formyltetrahydrofolate phosphatidate dehydrogenase: 1,4-benzoquinol adenosyltransferase: lipoyl methylenetetrahydrofolate nicotinate (to nicotinamide riboside) kinase: C4H07_RS18285 4-methyl-5-(2- 5-formyltetrahydrofolate cytidylyltransferase: acyl-CoA C4H07_RS08935 4-trans-3-oxo- an N-terminal- a (2E)-hexadec-2-enoyl- 527 a (2E)-dodec-2-enoyl- an acetyl-[acp a cis,cis-delta9,27- a cis,cis- a cis,cis- methylase UbiE: ubiE C4H07_RS04120 synthase: lipA (nicotinamide) 2,5-dichloro-trans 1 long chain a guanine methylenetetrahydrofolate dehydrogenase/ cyclo-ligase: SDR family dehydrogenase: 3-[(3aS,4S,5R,7aS)-5- a (7Z)-hexacos-7-enoyl-[acp] a malonyl-[acp] a butanoyl-[acp] N -methyladenine 2-oxoglutarate 1-methyl-dATP 2-oxoglutarate L-methionyl-L- 3-hydroxyC46:2- delta21,39-3- delta13,31- roseoflavin histidinol phosphooxyethyl) adenosylcob(III) heme a biosynthesis nucleotide C4H07_RS12675 -dienelactone undecenoyl-CoA [acp domain within in 16S rRNA [acp domain within domain within a repressor LexA + HMP-PP menaquinol-6 a [lipoyl-carrier reductase [NAD(P)H]: metF oxidoreductase: ATP cob(II)alamin polyphosphate NADP methenyltetrahydrofolate C4H07_RS03975 C4H07_RS18320 hydroxy-7a-methyl-1-oxo- DNA oxidative DNA oxidative acetyl-CoA C- alanyl-[protein] a fatty acid synthase] 16S rRNA a fatty acid synthase] fatty acid synthase] [acp] hydroxyC58:2- 3-hydroxy bifunctional thiazole alamin-[corrinoid protein]-N 6 -[(R)- adenylyltransferase: a CDP- ketoacyl-ACP synthase beta-ketoacyl-[acyl-carrier- type I methionyl SDR family histidinol cyclohydrolase FolD: folD C4H07_RS14135 [+ 12 isozymes] octahydro-1H-inden-4- carboxymethylenebutenolidase: demethylase demethylase acyltransferase: acyl-CoA (guanine(527)-N(7) acyl-CoA acyl-CoA [acp] SDR family C50:2-[acp]SDR family riboflavin kinase/ transcriptional adenosyltranferase] a 5,10- a 5,10- nadD adenosyl-cobinamide diacylglycerol III: C4H07_RS12260 cob(I)yrinic acid protein] synthase II: fabF aminopeptidase: oxidoreductase: dehydrogenase: dihydrolipoyl]-L-lysine protoheme [+ 5 isozymes] C4H07_RS13505 exopolyphosphatase: ppx synthetase: synthetase: synthetase: repressor thiamine methylenetetrahydrofolate methenyltetrahydrofolate phosphate (2E,5Z)- yl]-3-oxopropanoyl-CoA a,c-diamide AlkB: alkB AlkB: alkB C4H07_RS01465 )-methyltransferase C4H07_RS14135 oxidoreductase: oxidoreductase: FAD synthetase: hisD cob(I)yrinic acid protoheme IX nicotinate adenine CDP-diacylglycerol-- beta-ketoacyl-[acyl-carrier- ketoacyl-ACP synthase map + adenosyltransferase: an N-terminal L- C4H07_RS02235 RsmG: rsmG C4H07_RS02235 C4H07_RS02235 C4H07_RS14135 C4H07_RS14135 C4H07_RS10210 LexA: lexA NAD phosphate a (3R)-3- tetradecenoyl-CoA protein] synthase II: fabF III: C4H07_RS12260 [+ 3 isozymes] a palmitoyl-[acp 7 a dodecanoyl-[acp an acetoacetyl-[acp [+ 5 isozymes] folate transformations I a,c-diamide farnesyltransferase: bifunctional dinucleotide glycerol-3-phosphate 3- acetyl-CoA C- 2,5-dichloromaleylacetate succinate formaldehyde adenine succinate formaldehyde dATP long chain 2-trans- met an N - a cis,cis- roseoflavin synthase: hydroxydecanoyl-[acp] C4H07_RS04120 acetyl-CoA alanyl-[protein] 527 a cis,cis-[+ 5 isozymes] a cis,cis-[+ 5 isozymes] cleaved his adenosyltransferase: C4H07_RS19300 methylenetetrahydrofolate phosphatidyltransferase: acyl-carrier protein a (9Z)-3-oxooctacos-9-enoyl-[acp] a 3-oxohexanoyl-[acp] polyphosphate domain within a methylguanine domain within a domain within a delta9,27-3- NAD(+) NAD+ synthetase, ∆ 3 ∆ 2 acyltransferase: triphosphate adenosylcobalamin nonenoyl-CoA delta21,39-3- delta13,31-3- 5'-phosphate repressor LexA C4H07_RS18290 C4H07_RS04120 ferroheme o dehydrogenase/ 3-hydroxyacyl- pgsA -cis- -trans- enoyl-CoA fatty acid synthase] in 16S rRNA fatty acid synthase] fatty acid synthase] oxo-C46:2-[acp] diphosphatase: glutamine NAD+ synthase: adenosylcobinamide- C4H07_RS01465 oxo-C58:2-[acp] a tetrahydrofolate methenyltetrahydrofolate ACP dehydratase 1-(3-sn- enoyl-CoA hydratase/ oxo-C50:2-[acp] nudC adenosylcobalamin dependent: C4H07_RS06080 GDP [+ 3 isozymes] thiamine heme A synthase: cyclohydrolase FolD: folD FabZ: fabZ phosphatidyl) isomerase: isomerase C4H07_RS06080 C4H07_RS02455 family protein: phosphate C4H07_RS19305 -sn-glycerol an N-terminal- 966 a cis,cis-delta7,25- a cis,cis- NMN biotin biosynthesis from bifunctional 3-[(3aS,4S,5R,7aS)- 2-chloro-cis- an (S)-2- 3-oxo-(9Z)- 3-oxopalmitoyl- a trans-2,3-dehydroacyl- a guanine a palmitoyl-[acp an acyl-[acp a nucleoside + a (2E)-dec-2-enoyl-[acp] C4H07_RS02285 acetyl-CoA propanoate L-cysteate myristoyl-CoA a DNA segment thiamine- 8-amino-7-oxononanoate I methylenetetrahydrofolate NAD 3-phosphate 5-hydroxy-7a-methyl- a malonyl-[acp] methyl ester a malonyl-[acp] dienelactone cob(II)yrinate a stearoyl-[acp] halocarboxylate hexadecenoyl-CoA CoA L-methionyl-L- [acp domain within in 16S rRNA domain within a domain within a 3-hydroxyC44:2- delta19,31-3- 5'-nucleotidase ferroheme i (3E,5Z)-tetradeca- ATP acetyl-CoA C- diphosphate phosphate dehydrogenase/ phosphatidylglycerophosphatase [+ 7 isozymes] 1-oxo-octahydro-1H- ketoacyl-ACP synthase a,c-diamide beta-ketoacyl-[acyl-carrier- CoA-binding HAD family acetyl-CoA C- valyl-[protein]type I methionyl a fatty acid synthase] 16S rRNA fatty acid synthase] fatty acid synthase] [acp] SDR family aspartate/ hydroxyC50:2- acyl-CoA nucleoside- SurE: formyltetrahydrofolate 8-amino-7- thioredoxin enoyl-ACP 3,5-dienoyl-CoA carboxymethylenebutenolidase: hydrolase: acyltransferase: acyltransferase: acyl-CoA acyl-CoA acyl-CoA dehydrogenase: recombinase kinase: thiL lipoate biosynthesis methenyltetrahydrofolate A: C4H07_RS16960 indene-4-carboxyl-CoA III: C4H07_RS12260 cob(I)yrinic acid protein] synthase II: fabF protein: aminopeptidase: (guanine(966)-N(2) oxidoreductase: tyrosine/aromatic [acp] SDR family diphosphate C4H07_RS10025 deformylase: purU a 10- heme A synthase: oxononanoate pathway reductase (S)-3-hydroxy-(5Z) C4H07_RS13505 C4H07_RS01715 C4H07_RS17645 C4H07_RS17645 synthetase: synthetase: synthetase: C4H07_RS17655 RecA: recA adenosylmethionine- and incorporation cyclohydrolase FolD: folD an L-1- beta-ketoacyl-[acyl-carrier- a,c-diamide ketoacyl-ACP synthase C4H07_RS02415 map )-methyltransferase C4H07_RS14135 aminotransferase: oxidoreductase: kinase: thiamine formyltetrahydrofolateformyltetrahydrofolate C4H07_RS19305 FabI: fabI C4H07_RS02235 C4H07_RS02235 C4H07_RS02235 5'-3'- -tetradecenoyl-CoA adenosyltransferase: [+ 4 isozymes] [+ 3 isozymes] [+ 3 isozymes] an N-terminal 2 RsmD: rsmD C4H07_RS05255 C4H07_RS14135 [+ 12 isozymes] a DNA segment diphosphate -8-amino-7- III (Bacillus) an oxidized phosphatidyl- protein] synthase II: fabF III: C4H07_RS12260 met an acyl-[acp an N - a 3-oxooctadecanoyl- a 3-oxoacyl-[acp a cis,cis-[+ 5 isozymes] C4H07_RS10705 deoxyribonucleotidase: deformylase: purU a 10-formyltetrahydrofolate enoyl-ACP 2-chloromaleylacetate C4H07_RS04120 phosphate ADP propanoyl-CoA a (2R)-2- (7Z)- L-valyl-[protein] (2E)-tetradec- a nucleoside in reverse oxononanoate 4-amino-2-methyl-5- thioredoxin sn-glycerol 3-hydroxyacyl-CoA a halide anion acetyl-CoA myristoyl-CoA acetyl-CoA domain within a methylguanine 966 [acp domain within domain within a [+ 2 isozymes] a cis,cis-[+ 5 isozymes] glycine bifunctional bifunctional hydroxyferroheme i (3E,5Z)- (5R,7aS)-5-hydroxy- acyl-carrier protein a 3-oxoglutaryl-[acp] methyl ester adenosyl-cob(III) a 3-oxoicosanoyl-[acp] hydroxy fatty acid tetradecenoyl-CoA delta7,25-3- 2-enoyl-CoA triphosphate C4H07_RS18395 transaminase: an octanoyl-[acp] reductase FabI: dehydrogenase: triphosphate 3-sulfopyruvate delta19,31-3- orientation methylenetetrahydrofolate diphosphomethylpyrimidine tetradecadienoate 7a-methyl-1-oxo- yrinate a,c-diamide fatty acid synthase] in 16S rRNA a fatty acid synthase] fatty acid synthase] oxo-C44:2-[acp] 1-(β-D cleavage methylenetetrahydrofolate C4H07_RS10905 lipoyl(octanoyl) C4H07_RS03235 C4H07_RS08935 oxo-C50:2-[acp] 7,8- biosynthesis 3,5,6,7-tetrahydro-2H- ribofuranosyl) methionine system dehydrogenase/ dehydrogenase/ transferase thioredoxin- diaminopelargonate AIR 3-oxo-(5Z)- indene-4-carboxyl-CoA nicotinamide synthase: protein methenyltetrahydrofolate methenyltetrahydrofolate a [glycine-cleavageLipB: lipB disulfide a decanoyl-[acp] tetradecenoyl-CoA (1S,2R)-1- a holo-[acyl carrier 46 a 5,6- a cis,cis-delta5,23- a (3R,5Z)-3- a cis,cis- GcvH: cyclohydrolase FolD: folD cyclohydrolase FolD: folD dethiobiotin complex H protein] phosphomethylpyrimidine 5-chloro-trans (2E,6Z,9Z,12Z,15Z,18Z,21Z) an (R)-2- 6-cis, 3-oxo- 3-heptaprenyl-4- a guanine a (3R)-3- metH a (6S)-5- ferroheme a reductase: phosphatidylglycerol a holo [PedN acyl- 20 a uridine in tRNA 6 acetyl-CoA C- a (3Z)-dec-3-enoyl-[acp] a malonyl-[acp] a lignoceroyl-[acp] an octanoyl-[acp] C-(indol-3- protein] domain within dihydrouracil 3-hydroxyC42:2- hydroxy-tetradec- delta17,29-3- gcvH bifunctional synthase: N -octanoyl-L-lysine synthase ThiC: thiC trxB ketoacyl-ACP -dienelactone -tetracosaheptaenoyl-CoA halocarboxylate tridecenoyl-CoA ser hydroxybenzoate in tRNA ATP hydroxyacyl-CoA bifunctional formyltetrahydrofolate biosynthesis I (plastidic) acyltransferase: enoyl-CoA hydratase HAD family acetyl-CoA C- carrier protein] tRNA in tRNA hydroxyC48:2- bioD synthase III: (5R,7aS)-7a-methyl-1,5- beta-ketoacyl-[acyl-carrier- beta-ketoacyl-[acyl-carrier- beta-ketoacyl-[acyl-carrier- yl)glycerol 4-hydroxy-3- a fatty acid synthase tRNA [acp] SDR family 5-enoyl-[acp]SDR family tRNA acetoacetyl- methylenetetrahydrofolate methylenetetrahydrofolate HMP-P carboxymethylenebutenolidase: ACP S- acyl-CoA thioredoxin- C4H07_RS17645 protein] synthase II: fabF protein] synthase II: fabF protein] synthase II: fabF family protein: hydrolase: acyltransferase: 3-phosphate tryptophan polyprenylbenzoate (guanosine(46)-N7) oxidoreductase: oxidoreductase: [acp] SDR family dihydrouridine sulfate CoA dehydrogenase/ dehydrogenase/ 5-formyltetrahydrofolate C4H07_RS12260 DHAP dioxo-3,5,6,7-tetrahydro- dihydrouridine(20/ bis(guanylyl molybdenum dethiobiotin disulfide [+ 3 isozymes] C4H07_RS13505 C4H07_RS18325 C4H07_RS01715 C4H07_RS01465 synthase: trpB malonyltransferase: synthetase: -methyltransferase oxidoreductase: synthase reductase: methenyltetrahydrofolate bifunctional Alcohol Degradation 2H-indene-4-carboxyl-CoA ketoacyl-ACP synthase ketoacyl-ACP synthase ketoacyl-ACP synthase decarboxylase: ubiD 20a) synthase C4H07_RS14135 C4H07_RS01370 adenylyltransferase cofactor) biosynthesis methenyltetrahydrofolate cyclo-ligase: a [lipoyl-carrier protein] reductase: beta-ketoacyl- NAD(P)-dependent [+ 7 isozymes] [+ 3 isozymes] [+ 3 isozymes] C4H07_RS17490 fabD C4H07_RS02235 TrmB: trmB C4H07_RS14135 DusB: dusB phbB cyclohydrolase FolD: folD hydroxymethylpyrimidine (3Z)-dodec- III: C4H07_RS12260 III: C4H07_RS12260 III: C4H07_RS12260 D-glyceraldehyde a malonyl[PedN an acetyl-[acp an N 7 - DusA: dusA a cis,cis-[+ 5 isozymes] a (5Z)-3-oxo-[+ 5 isozymes] subunit CysD: cysD cyclohydrolase FolD: folD C4H07_RS03975 biotin synthase: N 6 -octanoyl-L-lysine trxB [acyl-carrier- glycerol-3- 5-chloromaleylacetate (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3- a (2R)-2- 4-cis- trp 2-heptaprenylphenol a 5,6-dihydrouridine a 2,3,4-saturated MoO - serine 3-enoyl-CoA a halide anion acetyl-CoA 46 20 a cis,cis-[+ 5 isozymes] 2 kinase/ protein] phosphate ethanol degradation II acyl-carrier protein a (5Z)-3-oxododec-5-enoyl-[acp] a 3-oxohexacosanoyl-[acp] a 3-oxodecanoyl-[acp] 3-phosphate acyl-carrier domain within a methylguanine a uracil in tRNA delta5,23-3- tetradec-5- APS molybdopterin hydroxymethyltransferase: C4H07_RS05990 hydroxytetracosahexaenoyl-CoA hydroxy fatty acid undecenoyl-CoA delta17,29-3- in tRNA 3-oxoacyl-CoA bifunctional lipoyl phosphomethylpyrimidine ∆3,∆2-enoyl- protein] fatty acid synthase] in tRNA oxo-C42:2-[acp] enoyl-[acp] C4H07_RS04675 a 5,10- folate polyglutamylation synthase II: fabF dehydrogenase: glycerol and glycerophosphodiester degradation (3R)-2-(2-carboxyethyl)- oxo-C48:2-[acp] cofactor bis(molybdenum methylenetetrahydrofolate synthase: lipA kinase: thiD a reduced CoA isomerase: methenyltetrahydrofolate biotin C4H07_RS02125 ethanol 3-methyl-6-oxocyclohex- cofactor) dehydrogenase/ a [lipoyl-carrier a 3-oxododecanoyl-[acp] sn-glycerol di-trans,poly-cis-undecaprenyl hydroxymethylpyrimidine/ thioredoxin C4H07_RS02455 1-ene-1-carboxyl-CoA synthase: mobA methenyltetrahydrofolate a tetrahydrofolate protein]-N 6 -[(R)- menaquinol-7 biosynthesis 3-phosphate S-(hydroxymethyl) glycerol bis(molybdenum phosphomethylpyrimidine (2E)-dodec- 2-chloro-trans (6Z,9Z,12Z,15Z,18Z)-3- 6-trans-3-oxo- (11Z)-(S)-3- guanine 37 a cis,cis-delta7,19- a (9Z)-3-oxo- a cis,cis- (3R)-3- cyclohydrolase FolD: folD phosphate biosynthesis glutathione a glycerophosphodiester a O- glutathione monochlorobimane a holo [PedD acyl- dihydrolipoyl]-L-lysine SDR family a cis-delta19-C38:1-[acp] a malonyl-[acp] a myristoyl-[acp] 2-oxoadipate carboxyphosphinopyruvate Phe NADH octadec-9- delta15,27-3- asp hydroxyoctadecanoyl- ala cofactor) kinase: C4H07_RS18285 all-trans- glycerol-3- 2-enoyl-CoA -dienelactone oxotetracosapentaenoyl-CoA tridecenoyl-CoA hydroxyhexadec- in tRNA 3-hydroxyC38:2- a 5-methyltetrahydrofolate a 5,10- dehydrogenase/ sialoglycoprotein carrier protein] molybdenum cofactor (2E,6E)-farnesyl 1,4-dihydroxy- oxidoreductase: phosphate 1-O- glycerol ketoacyl-ACP synthase beta-ketoacyl-[acyl-carrier- acetyl-CoA C- glutathione S- acetyl-CoA C- 2-oxoglutarate 11-enoyl-CoA tRNA NAD(+) [acp] SDR family enoyl-[acp]SDR family hydroxyC46:2- CoA methylenetetrahydrofolate serine bifunctional IPP heptaprenyl class III alcohol enoyl-CoA tRNA (adenosine(37)-N6)- oxaloacetate 3-hydroxyacyl-CoA acetoacetyl- diphosphate HMP-PP 2-naphthoate C4H07_RS14135 kinase 9-carboxy-6-methyl-3,7- carboxymethylenebutenolidase: acyltransferase: transferase: acyltransferase: dehydrogenase ACP S- (guanosine(37)-N1) diphosphatase: [acp] SDR family aspartate alanine guanylyltransferase hydroxymethyltransferase: tetrahydrofolate di-trans,poly-cis- diphosphate acyltransferase glycerophosphodiester hydratase III: C4H07_RS12260 protein] synthase II: fabF threonylcarbamoyltransferase decarboxylase: oxidoreductase: oxidoreductase: CoA dehydrogenase: C4H07_RS13505 C4H07_RS17645 C4H07_RS01465 malonyltransferase: dehydrogenase: nudC dehydrogenase: transaminase: MobA: mobA methylenetetrahydrofolate C4H07_RS04675 synthase/ [+ 5 isozymes] PlsY: plsY phosphodiesterase: ugpQ GlpK: glpK family protein: dioxononanoyl-CoA beta-ketoacyl-[acyl-carrier- ketoacyl-ACP synthase complex transferase C4H07_RS00400 E1 component: C4H07_RS16115 -methyltransferase C4H07_RS14135 C4H07_RS01370 oxidoreductase: reductase: guanylyl molybdenum a 10- decaprenylcistransferase: C4H07_RS19380 fabD C4H07_RS08935 reduced β- C4H07_RS01955 C4H07_RS05660 bis(guanylyl glutathione- demethylmenaquinol-7 a 1-acyl-sn [+ 3 isozymes] [+ 5 isozymes] [+ 3 isozymes] C4H07_RS14155 1 TrmD: trmD C4H07_RS14135 reductase [NAD(P)H]: metF dihydrofolate formyltetrahydrofolate di-trans,octa-cisuppS glutathione a (3R)-3- acetaldehyde C4H07_RS18325 protein] synthase II: fabF III: C4H07_RS12260 subunit TsaD: tsaD 3-(hydroxyphosphinoyl) a malonyl- (11Z)-3- an N - a cis,cis-[+ 5 isozymes] a (3R,9Z)-3-[+ 5 isozymes] phbB cofactor biosynthesis glutaredoxin -glycerol 3- acetyl-CoA C- 2-chloromaleylacetate (4Z,7Z,10Z,13Z,16Z)- (glutathion- 4-trans- nicotinamide D- AMP 3-oxooctadecanoyl- molybdopterin) a 5,10- synthase: folC biosynthesis hydroxydodecanoyl-[acp] sn-glycerol acetyl-CoA acetyl-CoA glutaryl-CoA NADH CO pyruvate [PedD acyl- oxohexadecenoyl- methylguanine 37 a cis,cis-[+ 5 isozymes] oxaloacetate pyruvate glutathione-peroxide redox reactions menaquinol-8 biosynthesis bifunctional -undecaprenyl bifunctional [+ 7 isozymes] acyl-carrier protein a cis-delta21-3-oxo-C40:1-[acp] a 3-oxohexadecanoyl-[acp] a peptide docosapentaenoyl-CoA S-yl)-bimane undecenoyl-CoA 2 ribonucleotide delta7,19-3- hydroxy-octadec- cofactor MoO - redox reactions phosphate acyltransferase: Phe delta15,27-3- CoA 2 methylenetetrahydrofolate diphosphate aldehyde 3-phosphate (S)-3- carrier protein] CoA in tRNA oxo-C38:2-[acp] 9-enoyl-[acp] molybdopterin tetrahydrofolate demethylmenaquinone 3-hydroxyacyl- 1-acyl-sn-glycerol- C4H07_RS01465 oxo-C46:2-[acp] glutathione bifunctional undecaprenyl- cys glu dehydrogenase cofactor a tetrahydrofolate synthase/ methyltransferase/2- ACP dehydratase 3-phosphate hydroxydodecanoyl-CoA GSSG demethylmenaquinol-8 molybdenum cofactor family protein: [+ 3 isozymes] tetrahydrofolate dihydrofolate diphosphate glutamate-- methoxy-6-polyprenyl- FabZ: fabZ 3-hydroxyacyl-CoA bifunctional guanylyltransferase acyltransferase: synthase/ phosphatase: cysteine ligase: C4H07_RS18065 a (2E)-tetradec-2-enoyl- 37 a (7Z)-3- a cis,cis- synthase: folC 1,4-benzoquinol dehydrogenase: 3-(4-hydroxyphenyl)- (E)-1-(L-cystein-S-yl)-N-hydroxy- 3-oxo-(11Z)- + 1-carboxyvinyl a guanine a [protein] (L-serine/L- demethylmenaquinone MobA: mobA C4H07_RS18255 7-carboxy-4-methyl- trans-dienelactone a cis- sn-glycerol NADH menadione H 2,2-dichloroacetate a 3-oxoglutaryl- [DNA] a reduced dihydrofolate C4H07_RS08865 γ C4H07_RS02100 a (2E)-dodec-2-enoyl-[acp] aldehyde DHAP C4H07_RS08935 acetyl-CoA a cis-delta17-C36:1-[acp] a malonyl-[acp] a behenoyl-[acp] 3-oxo-propanoyl-CoA ω-(methylsulfanyl)butan-1-imine octadecenoyl-CoA carboxyphosphonate [acp domain within S-ethyl-L-cysteine in tRNA oxohexacos- delta13,25-3- ser a 10- -L-glutamyl- methylase UbiE: ubiE 5-oxoheptanoyl-CoA vaccenoyl-[acp] 3-phosphate [acp] methyl ester threonine) phosphate glutathione glutathione glutathione- methyltransferase/2- molybdopterin- glutaredoxin synthase: folC 1-acyl-sn-glycerol- dehydrogenase: ketoacyl-ACP synthase beta-ketoacyl-[acyl-carrier- acetyl-CoA C- cystathionine acetyl-CoA C- NADH-quinone a fatty acid synthase] tRNA glutathione S- 7-enoyl-[acp]SDR family hydroxyC44:2- DNA formyltetrahydrofolate di-trans,octa-cis- L-cysteine glycerol-3- oxaloacetate cystathionine SDR family protein peroxidase: peroxidase: disulfide methoxy-6-polyprenyl- guanine menaquinol-7 3-phosphate 3-oxododecanoyl-CoA carboxymethylenebutenolidase: acyltransferase: beta-lyase: metC acyltransferase: oxidoreductase acyl-CoA (guanosine(37)-N1) transferase: [acp] SDR family polymerase L-serine a 5,10- undecaprenyl phosphate glutathione enoyl-ACP C4H07_RS10955 III: C4H07_RS12260 protein] synthase II: fabF phosphate 1-O- decarboxylase: beta-lyase: metC oxidoreductase: oxidoreductase: phosphatase C4H07_RS13275 1,4-benzoquinol dinucleotide glutaredoxin acyltransferase: C4H07_RS13505 C4H07_RS01465 C4H07_RS17645 synthetase: C4H07_RS00400 III subunit ammonia-lyase: C4H07_RS13275 reductase: gorA methylenetetrahydrofolate reductase beta-ketoacyl-[acyl-carrier- ketoacyl-ACP synthase acyltransferase cystathionine subunit M: C4H07_RS16115 -methyltransferase C4H07_RS14135 C4H07_RS14135 oxidoreductase: methylase UbiE: ubiE 3: grxC synthase: C4H07_RS00195 acetate acetyl-CoA C- C4H07_RS02235 cystathionine CheZ: cheZ C4H07_RS13495 biosynthesis FabI: fabI [+ 3 isozymes] beta-lyase: metC [+ 3 isozymes] C4H07_RS15685 1 TrmD: trmD [+ 5 isozymes] C4H07_RS14135 epsilon: dnaQ acyl carrier gshB a 1,2-diacyl- (2E)-7-carboxy-4-methyl- protein] synthase II: fabF III: C4H07_RS12260 PlsY:1-cis plsY-vaccenoyl- ω a myristoyl-[acp beta-lyase: metC an N - a (3R)-3-[+ 5 isozymes] a (3R,7Z)-3-[+ 5 isozymes] menaquinol-8 guanylylprotein B: mobB a protein with acyltransferase: 2-maleylacetate (E)- -(methylsulfanyl) + carboxyphosphinopyruvate a [protein] Ser/Thr a nucleoside 5'- enoyl-ACP acetyl-CoA 4-hydroxybenzoyl-CoA pyruvate palmitoleoyl-CoA acetyl-CoA menadiol NAD 37 glyoxylate a cis,cis-[+ 5 isozymes] pyruvate protein activation sn-glycerol acetyl-CoA C4H07_RS17645 5-oxohept-2-enoyl-CoA acyl-carrier protein a cis-delta19-3-oxo-C38:1-[acp] a 3-oxotetracosanoyl-[acp] acyl-carrier protein sn-glycerol- butyl-thiohydroximate domain within a pyruvate ethanethiol methylguanine hydroxyglutaryl- hydroxyhexacos- glutathione molybdenum reduced L- octaprenyl diphosphate delta13,25-3- monophosphate glutathione reductase FabI: 3-phosphate synthetase: enoyl-CoA 3-phosphate fatty acid synthase] in tRNA [acp] methyl ester 7-enoyl-[acp] an apo acyl- cofactor cysteine residues biosynthesis [+ 3 isozymes] oxo-C44:2-[acp] C4H07_RS03235 phosphatidate C4H07_RS02270 hydratase/ carrier protein (2E,6E)-farnesyl cytidylyltransferase: [+ 3 isozymes] decanoyl-CoA isomerase holo-ACP synthase: IPP a dodecanoyl-[acp] diphosphate C4H07_RS12675 family protein: an (R)-2- an electron- 3-oxo-(7Z)- an N-terminal- a (2E)-octadec-2-enoyl- a hexanoyl-[acp a (5Z)-3- a cis,cis- C4H07_RS11375 + a 3-oxoicosanoyl- + octaprenyl acetyl-CoA acyl-CoA sulfite [DNA] NADH H dihydrolipoamide domain within a palmitoyl-CoA a quinone phosphoenol NAD a holo acyl- Secondary Metabolite Biosynthesis a CDP- C4H07_RS02285 a cis-delta13-C32:1-[acp] a malonyl-[acp] a dodecanoyl-[acp] halocarboxylate transfer quinone tetradecenoyl-CoA L-methionyl- [acp domain within S-benzyl-L-cysteine oxotetracos- delta11,23-3- dGDP diphosphate dehydrogenase: nitrite/sulfite [acp] diacylglycerol ketoacyl-ACP synthase exodeoxyribonuclease HAD family NADH-quinone acetyl-CoA C- dihydrolipoyllysine- glycyl-[protein] a fatty acid synthase] fatty acid synthase] acyl-CoA 5-enoyl-[acp]SDR family hydroxyC42:2- quinone pyruvate carrier protein synthase: ispB ketoacyl-ACP [+ 7 isozymes] beta-ketoacyl-[acyl-carrier- type I methionyl cystathionine SDR family C4H07_RS17655 reductase: III: xth hydrolase: oxidoreductase acyltransferase: residue acyl-CoA acyl-CoA dehydrogenase: [acp] SDR family pyruvate NAD kinase: all-trans-octaprenyl methylerythritol synthase III: CDP-diacylglycerol-- (3R)-7-carboxy-3-hydroxy-4- III: C4H07_RS12260 protein] synthase II: fabF aminopeptidase: beta-lyase: metC oxidoreductase: oxidoreductase: oxidoreductase: alcaligin [+ 12 isozymes] C4H07_RS16500 C4H07_RS01715 subunit M: C4H07_RS17645 acetyltransferase: synthetase: synthetase: C4H07_RS17655 oxidoreductase: kinase: pyk C4H07_RS07135 diphosphate phosphate pathway I C4H07_RS12260 glycerol-3-phosphate 3- methyl-5-oxoheptanoyl-CoA beta-ketoacyl-[acyl-carrier- an oxidized ketoacyl-ACP synthase exodeoxyribonuclease map cystathionine C4H07_RS14135 C4H07_RS14135 C4H07_RS09630 biosynthesis [+ 3 isozymes] C4H07_RS15685 [+ 3 isozymes] aceF an N-terminal C4H07_RS02235 C4H07_RS02235 [+ 12 isozymes] C4H07_RS14135 laurate phosphatidyltransferase: (2E)-dec-2-enoyl-CoA protein] synthase II: fabF H O ferredoxin [iron- hydrogen sulfide III: C4H07_RS12260 III: xth met a stearoyl-[acp a 3-oxooctanoyl- [+ 5 isozymes] [+ 5 isozymes] 3-hydroxyacyl-CoA 2 a 2'- an (S)-2- an electron- (5Z)- beta-lyase: metC (2E)- a (3R)-3- a (3R,5Z)-3- dGTP pyruvate + D-glyceraldehyde beta-ketoacyl- + glycyl-[protein] a cis,cis- a semiquinone NADP pyruvate sulfur] cluster a halide anion NAD acetyl-CoA S-acetyldihydrolipoamide domain within a [acp domain within [+ 5 isozymes] 3-phosphate [acyl-carrier- pgsA dehydrogenase: acyl-carrier protein a cis-delta15-3-oxo-C34:1-[acp] a 3-oxotetradecanoyl-[acp] deoxyribonucleoside [DNA] hydroxyarboxylate transfer quinol dodecenoyl-CoA pyruvate benzyl thiol hexadecenoyl-CoA hydroxyicosanoyl- hydroxytetracos- putrescine long-chain fatty enoyl-CoA delta11,23-3- protein] 1-(3-sn- C4H07_RS08935 5'-monophosphate fatty acid synthase] a fatty acid synthase] [acp] 5-enoyl-[acp] 1-deoxy-D-xylulose- acid--CoA ligase: hydratase oxo-C42:2-[acp] synthase II: fabF phosphatidyl) 7-carboxy-4-methyl-3,5- 5-phosphate C4H07_RS15820 family protein: peptidoglycan biosynthesis I Cell Structure Biosynthesis -sn-glycerol dioxoheptanoyl-CoA lipid IV biosynthesis (P. putida) Kdo transfer to lipid synthase: N-hydroxyputrescine [+ 6 isozymes] C4H07_RS18325 α (meso-diaminopimelate containing) superpathway of (Kdo) -lipid A biosynthesis A 3-phosphate -D-Kdo-(2->4) an (S)-2- 3 5-cis, 7-trans-3-oxo- (5E)-3-oxo- a butanoyl-[acp (11Z)- a (6Z)-3- a [lipoyl-carrier 2 a 10- an L-methionyl- ADP-L-glycero-β- an N -methyladenine MoO - a peptide with a a 3-oxopimeloyl- phosphoenol IV II (Haemophilus) C4H07_RS05595 [+ 7 isozymes] anthranilate α 2 3-oxopropanoate 6 ferroheme o A a 3-oxotetradecanoyl-[acp] phosphatidylglycerophosphatase a cis-delta15-C34:1-[acp] a malonyl-[acp] Met - -D-Kdo-(2->6) halocarboxylate tetradecadienoyl-CoA dodec-5- domain within a hexadecenoyl-CoA oxooctadec- protein]-N -[(R) phosphoenol UDP-N-acetyl- lauroyl-CoA acetyl-CoA C- formyltetrahydrofolate [initiator tRNA ] D-manno-heptose in DNA molybdopterin ATP leader sequence [acp] methyl ester dADP pyruvate a (3R)-3- a (3R)-3- UDP-N-acetyl- 1-deoxy-D-xylulose myo-inositol (S)-3- 2-aminobenzoate- -lipid A (E. coli) HAD family DNA-3- acetyl-CoA C- enoyl-CoA malonic fatty acid synthase] acyl-CoA 6-enoyl-[acp] -dihydrolipoyl]- pyruvate α-D-glucosamine lipid IV (E. coli) CMP-Kdo A: C4H07_RS16960 acyltransferase: ketoacyl-ACP synthase methionyl-tRNA lipopolysaccharide cofactor signal acetyl-CoA C- SDR family SDR family UDP-N-acetyl- hydroxytetradecanoyl- α A molybdenum cofactor acyl-CoA heme A synthase: pyruvate hydroxydecanoyl-[acp] -D-glucosamine 5-phosphate biosynthesis SDR family an L-1- hydroxydecanoyl-CoA III: C4H07_RS12260 formyltransferase: CoA ligase: heptosyltransferase hydrolase: methyladenine acyltransferase: peptidase semialdehyde dehydrogenase: oxidoreductase: oxidoreductase: L-lysine dihydrolipoyl pyruvate UDP-N-acetylglucosamine α-D-glucosamine [acp] acyl-ACP--UDP-N- 3-deoxy-D-manno- C4H07_RS01465 acyltransferase: C4H07_RS19305 kinase: pyk N-hydroxy-N- oxidoreductase: C4H07_RS01855 C4H07_RS18315 I: waaC C4H07_RS01715 glycosylase I: C4H07_RS01465 guanylyltransferase reductase: synthetase: C4H07_RS17655 dehydrogenase: kinase: pyk 1-carboxyvinyltransferase: acetylglucosamine O- 1-deoxy-D-xylulose- D-glucopyranose phosphatidyl- 3-hydroxyacyl-CoA [+ 3 isozymes] beta-ketoacyl-[acyl-carrier- an N-formyl- I: lepB C4H07_RS01465 C4H07_RS14135 C4H07_RS14135 octulosonic acid succinyl-putrescine C4H07_RS05380 adenylyl MobA: mobA C4H07_RS13585 C4H07_RS02235 murA UDP-3-O-[(3R)-3-acyltransferase: lpxA 5-phosphate C4H07_RS14135 sn-glycerol dehydrogenase: protein] synthase II: fabF L-methionyl- a tetrahydrofolate heptosyl- [+ 3 isozymes] [+ 3 isozymes] a 3-oxohexanoyl- [+ 12 isozymes] [+ 5 isozymes] [+ 5 isozymes] C4H07_RS10075 acyl-ACP--UDP-N- transferase: 6-phosphate diphosphate AMP anthraniloyl-CoA ADP an (S)-2- an apurinic site (3Z,5E)-dodec- molybdenum a leader sequence a peptide [+ 3 isozymes] (2E,11Z)-hexadec- a (3R)-3- a (3R,6Z)-3- ferroheme a dATP pyruvate pyruvate reductoisomerase: [+ 5 isozymes] C4H07_RS08935 met Kdo -lipid A a halide anion 3-methyladenine acetyl-CoA (3E)-dec-3- 3-hydroxypropanoate a [lipoyl-carrier[+ 3 isozymes] UDP-N-acetyl-α- acetylglucosamine O- hydroxydecanoyl]-N- C4H07_RS00495 5-carboxy-2-methyl- acyl-carrier protein a cis-delta17-3-oxo-C36:1-[acp] [initiator tRNA ] 2 acetyl-CoA [acp domain within hydroxypimeloyl- hydroxyoctadec- α-Kdo-(2->6)- stearate biosynthesis hydroxyarboxylate within DNA 3,5-dienoyl-CoA cofactor 2,11-dienoyl-CoA 6 acetyl-α-D-glucosamine C4H07_RS12670 acetyl-CoA enoyl-CoA a fatty acid synthase] protein]-N - D-glucosamine- acyltransferase: lpxA lipid IV (E. coli) a (3R)-3- II (bacteria and plants) 3-oxodecanoyl-CoA 3-oxopentanoyl-CoA [acp] methyl ester 6-enoyl-[acp] D-ribulose 5-phosphate UDP-3-O-acyl-N- A lipoyl-L-lysine enolpyruvate 3-[4-amino-3- Ins(3)P hydroxytetradecanoyl-[acp] acetylglucosamine 3-deoxy-D-manno- MEP fatty acid elongation -- saturated UDP-N- UDP-3-O-[(3R)-3- hydroxybutyl]- acetyl-CoA C- deacetylase: octulosonic inositol 3-hydroxyacyl- a palmitoyl-[acp] α hydroxymyristoyl]-N- hydroxy- acyltransferase: -Kdo-(2->4)- (5Z,8Z,11Z,14Z,17Z) a reduced dehydro(indole- 1939 a decanoyl-[acp a (7Z)-3-oxo- a (3R)-3- acetylmuramate acid kinase: ACP dehydratase beta-ketoacyl- a proteinogenic ADP-L-glycero-β- a 5' triphospho- 3-nonaprenyl-4- a uracil a supercoiled a 1,2-diacyl- acetyl-α-D-glucosamine C4H07_RS04345 2-C-methyl-D- carbamoyl- monophosphatase: a malonyl-[acp] α coenzyme A + + glutathione palmitoleoyl-CoA hexadec-7- dehydrogenase: an acetoacetyl-[acp] C4H07_RS17645 succinyl-CoA propanoyl-CoA a cis-delta11-C30:1-[acp] leukotriene-C4 CTP ATP -Kdo-(2->6)- -icosapentaenoate ferredoxin [iron- NADP H 3-yl)acetonitrile [mRNA] hydroxybenzoate an S-alkyl-L-cysteine in 23S rRNA domain within a hydroxyhexacosanoyl- duplex DNA sn-glycerol UDP-3-O-(3- C4H07_RS11795 erythritol 4-phosphate C4H07_RS05515 FabZ: fabZ [acyl-carrier- amino acid a tRNA precursor D-manno-heptose GTP murB aldehydo-D-arabinose UDP-3-O-acyl-N- propanoate ketoacyl-ACP synthase lipid IV (E. coli) lipopolysaccharide long-chain fatty sulfur] cluster glutathione S- 23S rRNA fatty acid synthase] acyl-CoA enoyl-[acp]SDR family [acp] hydroxydecanoyl) α [+ 3 isozymes] gamma- A ferredoxin-- RNA 4-hydroxy-3- cystathionine 3-hydroxyacyl- replicative diacylglycerol acetylglucosamine 4-O-phospho- - cytidylyltransferase: protein] CCA tRNA transferase: (uracil(1939)-C(5)) acyl-CoA dehydrogenase: 5-phosphate inositol a (2E)-tetradec-2-enoyl-[acp] III: C4H07_RS12260 glutamyltransferase: ggt heptosyltransferase acid--CoA ligase: NADP reductase: pyrophosphohydrolase: polyprenylbenzoate beta-lyase: metC oxidoreductase: ACP diguanylate cyclase: DNA helicase: kinase: UDP-N-acetyl- deacetylase: -α-D-glucosamine Kdo-(2->6)-lipid IV C4H07_RS15745 synthase nucleotidyltransferase: synthetase: A monophosphatase: octanoyl-CoA C4H07_RS01755 C4H07_RS00400 -methyltransferase C4H07_RS17655 C4H07_RS14755 ala α UDP-3-O-(3- beta-ketoacyl-[acyl-carrier- [+ 2 isozymes] I: waaC an oxidizedC4H07_RS08020 C4H07_RS16260 decarboxylase: ubiD cystathionine C4H07_RS01370 dehydratase C4H07_RS05630 C4H07_RS16980 -D-muramate C4H07_RS04345 4-(cytidine 5'- II: fabF α γ a tRNA C4H07_RS03965 RlmD: rlmD C4H07_RS02235 a 1,2-diacyl- glu C4H07_RS08855 enoyl-ACP protein] synthase II: fabF an -( -L-glutamyl) heptosyl- [+ 6 isozymes] [+ 5 isozymes] a 5'-phospho- a 3-oxododecanoyl- [+ 12 isozymes] [+ 5 isozymes] FabZ: fabZ diguanylate cyclase: a single UDP-3-O-(3- hydroxymyristoyl) diphospho)-2-C- ketoacyl-ACP acyl-CoA β leukotriene-D4 containing a ADP (5Z,8Z,11Z,14Z,17Z) NADPH ferredoxin [iron- (glutathion-S-yl)(1H- 2-nonaprenylphenol beta-lyase: metC a 5-methyluracil 1939 (2E,9Z)- a (3R,7Z)-3- UDP-N- pre-alcaligin reductase fatty acid -oxidation I -L-amino acid Kdo -lipid IV [mRNA] [acp domain within a trans-hexacos- C4H07_RS17065 stranded DNA sn-glycerol D-arabinofuranose hydroxymyristoyl) glucosamine N- methyl-D-erythritol myo-inositol synthase III: dehydrogenase: acyl-carrier protein a cis-delta13-3-oxo-C32:1-[acp] 3' CCA end 2 A -icosapentaenoyl-CoA sulfur] cluster indol-3-yl)acetonitrile pyruvate an alkyl-thiol in 23S rRNA hexadecenoyl-CoA hydroxy-hexadec- acetylmuramate-- glutamate FabI: fabI a 3-oxoacyl-[acp] a fatty acid synthase] 2-enoyl-[acp] c-di-GMP 3-phosphate 5-phosphate -α-D-glucosamine acyltransferase: 4-(cytidine 5'- C4H07_RS12260 C4H07_RS17655 7-enoyl-[acp] L-alanine ligase: racemase: lpxD diphospho) a 3-oxooctadecanoyl- a (3Z)-alk-3-enoyl-CoA 3-deoxy-8- UDP-3-O-(3- enoyl-ACP [+ 12 isozymes] C4H07_RS04320 C4H07_RS13425 hydroxymyristoyl) UDP-2-N-[(3R)-3- -2-C-methyl- reductase FabI: [acp] phosphooctulonate L-alanyl-γ-D- 34 UDP-N-acetyl- ∆ 3 2 2,3,5,6- a 1-acyl-2- 3-decaprenyl-4- an octanoyl-[acp a cytidine a (3R)-3- glucosamine N- hydroxydodecanoyl]-3-O- D-erythritol C4H07_RS03235 SDR family (2E)-oct-2-enoyl-CoA -cis-∆ -trans- a proteinogenic carbamoyl glutathione RX a [protein] Ser/Thr 4,5- a cis-delta21-3- long chain α synthase: alcaligin beta-ketoacyl- a cis-delta9-C28:1-[acp] a malonyl-[acp] glutathione glutathione a pimeloyl-[acp] L-ornithine arachidonoyl- glutamyl-L-lysyl- domain within a hydroxytetracosanoyl- propionamide -D-muramoyl- D-glt [(3R)-3-hydroxydecanoyl]- kinase: ispE glutathione hypoglycin A tetrachlorohydroquinone ala hydroxybenzoate dihydroxyphthalate in tRNA polyphosphate C4H07_RS11980 acyltransferase: oxidoreductase: [acyl-carrier- SDR family enoyl-CoA amino acid phosphate CTP oxo-C40:1-[acp] L-alanine α-D-glucosamine 2-phospho-4-(cytidine enoyl-CoA ketoacyl-ACP synthase gamma- gamma- glutathione S- 8-amino-7- ornithine sn-glycerol D-alanyl-D-alanineD-alanyl-D-alanine 4-hydroxy-3- glutathione S- HPr kinase/ fatty acid synthase] ABC transporter tRNA (cytidine(34) [acp] 3-hydroxyacyl- SDR family amidase: lpxD a myristoyl-[acp] C4H07_RS14135 protein] oxidoreductase: isomerase: acyl-CoA 5'-diphospho)-2-C- hydratase III: C4H07_RS12260 glutamyltransferase: ggt glutamyltransferase: ggt transferase: oxononanoate carbamoyltransferase: 3-phosphatephosphatidate carboxypeptidase: polyprenylbenzoate transferase: phosphorylase: substrate- -2'-O)- ACP oxidoreductase: C4H07_RS19220 polyphosphate UDP-2-N,3-O-bis[(3R)- UDP-2,3- [+ 5 isozymes] C4H07_RS02455 UDP-N- KDO-8P synthase C4H07_RS01370 family protein: C4H07_RS00400 cytidylyltransferase: C4H07_RS00400 C4H07_RS02585 synthetase: binding protein: methyltransferase: C4H07_RS14135 kinase 1: ppk1 3-hydroxytetradecanoyl]- diacylglucosamine methyl-D-erythritol ketoacyl-ACP a (3R)-3- beta-ketoacyl-[acyl-carrier- [+ 2 isozymes] [+ 2an isozymes] α-(γ-L- synthase: bioF argF L-alanyl-C4H07_RS00540γ-D- decarboxylase: ubiD dehydratase [+ 11 isozymes] II: fabF [+ 5 isozymes] [+ 5 isozymes] 8-amino-7- a CDP-1-acyl-C4H07_RS12675 C4H07_RS02235 C4H07_RS02535 C4H07_RS02115 acetylmuramoyl- α-D-glucosamine 2-C-methyl-D- synthase III: C4H07_RS18325 protein] synthase II: fabF L-cysteinylglycine glutamyl)-L- acyl-carrier protein L-citrulline D-ala glutamyl-L- [+ 5 isozymes] a [protein] (L-serine/L- a 3-oxodecanoyl- a 2'-O- FabZ: fabZ [+ 5 isozymes] diphosphatase: hydroxyoctadecanoyl- a trans-2-enoyl-CoA L-cysteinylglycine hypoglycin B 2,3,5-trichloro-6-(glutathion- 2-arachidonoyl- 2-decaprenylphenol a glutathione- a cis-delta21-3- propanoate long chain L-alanine--D- preQ biosynthesis ketoacyl-ACP enoyl-CoA oxononanoate HX protocatechuate 34 a trans-tetracos- UDP-2,3- C4H07_RS08870 erythritol 2,4- 0 C4H07_RS12260 [acp] [+ 7 isozymes] acyl-carrier protein a cis-delta11-3-oxo-C30:1-[acp] amino acid lysyl-D-alanine threonine) phosphate [acp domain within methylcytidine hydroxyC40:1- glutamate ligase: a 2,3,4-saturatedsynthase III: a (3R)-3-hydroxyacyl- hydratase/ S-yl)-hydroquinone glycerol S-conjugate 2-enoyl-[acp] polyphosphate diacylglucosamine cyclodiphosphate beta-ketoacyl- 3-hydroxyacyl- (S)-3- long-chain fatty a fatty acid synthase] in tRNA [acp] C4H07_RS04305 UDP-2,3- fatty acyl-[acp]C4H07_RS12260 [acyl-carrier protein] isomerase α diphosphatase: synthase: [acyl-carrier- hydroxyoctanoyl-CoA acid--CoA ligase: -Kdo diacylglucosamine ACP 3-hydroxyacyl- a 2,3,4-saturated family protein: 3-hydroxybutyryl- C4H07_RS15750 GTP coenzyme A C4H07_RS01755 a (3R)-3- C4H07_RS08870 diphosphatase: protein] dehydratase ACP 3-hydroxyacyl-CoA fatty acid acyl-CoA CoA epimerase: UDP-N-acetyl- C4H07_RS02285 hydroxyacyl-CoA (6Z,9Z,12Z,15Z,18Z,21Z)-3- (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3- a 4-hydroxy-3- 24-hydroxy-3- a (2E)-oct-2-enoyl- a uracil 1498 meso- 3-deoxy-manno- GTP synthase II: fabF FabZ: fabZ dehydrogenase: [+ 6 isozymes] a 5-L-glutamyl- (3S,6Z,9Z,12Z,15Z,18Z)-3- glutathione fenclorim L-2,4- an L-glutamyl- a cis-delta17-3- DNA with lesion α-D-muramoyl-L- UDP-2,3- C4H07_RS11920 2-C-methyl-D-erythritol- dehydratase dehydrogenase: C4H07_RS02455 an acyl-[acyl-carrier protein] a malonyl-[acp] glu H O NAD + an amino acid a PII protein UTP oxocholest-4- [acp domain within (R)-NADPHX diaminopimelate octulosonate peptidoglycan maturation (meso-diaminopimelate containing) cyclohydrolase [+ 7 isozymes] 2 [peptide] oxotetracosahexaenoyl-CoA hydroxytetracosapentaenoyl-CoA hydroxytetracosahexaenoyl-CoA ATP a ribonucleic acid polyprenylbenzoate diaminobutanoate in 16S rRNA [tRNA Gln ] oxo-C36:1-[acp] diacylglucosamine 2,4-cyclodiphosphate a (2E)-octadec- FabZ: fabZ C4H07_RS08935 C4H07_RS18320 acetyl-CoA C- glutathione S- en-26-oyl-CoA a fatty acid synthase] excinuclease alanyl-D-glutamate cytidylyltransferase: lipid X (P. putida) I FolE2: beta-ketoacyl-[acyl-carrier- Glu/Leu/Phe/Val gamma- 3-hydroxyacyl-CoA 3-hydroxyacyl-CoA [protein-PII] 4-hydroxy-3- 16S rRNA Asp-tRNA(Asn) SDR family NAD(P)H-hydrate diphosphatase: a 3-oxohexadecanoyl-[acp] 2-enoyl-[acp] a 2,3,4-saturated[+ 12 isozymes] a 2,3,4-saturated (3S acyltransferase: polynucleotide transferase: 3-hydroxyacyl-CoA acyl-CoA diaminobutyrate ABC subunit kdsB lipid II (meso flavodoxin- 7,8- C4H07_RS05600 3-oxooctanoyl-CoA protein] synthase II: fabF dehydrogenase: glutamyltransferase: ggt dehydrogenase: dehydrogenase: uridylyltransferase: polyprenylbenzoate (uracil(1498)-N(3))- /Glu-tRNA(Gln) oxidoreductase: epimerase: C4H07_RS11920 fatty acyl CoA )-3-hydroxyacyl-CoA C4H07_RS17645 adenylyltransferase C4H07_RS00400 dehydrogenase: synthetase: acetyltransferase: UvrA: uvrA bifunctional UDP- lipid-A-disaccharide diaminopimelate containing) dependent dihydroneopterin SDR family enoyl-ACP 3-hydroxyacyl-CoA ketoacyl-ACP synthase C4H07_RS08635 an[+ α 2-(5-L- isozymes] C4H07_RS08935 C4H07_RS08935 C4H07_RS12710 decarboxylase: ubiD methyltransferase: amidotransferase: C4H07_RS14135 C4H07_RS06155 CMP-Kdo PcnB: pcnB C4H07_RS08935 C4H07_RS02235 ectA N-acetylmuramoyl- monofunctional 3'-triphosphate acetyl-CoA C- dehydrogenase: + [+ 3 isozymes] a uridylylated [+ 5 isozymes] 3 C4H07_RS14805 gatC gatA gatB [+ 3 isozymes] lipid X synthase: (E)-4-hydroxy- oxidoreductase: reductase enoyl-ACP III: C4H07_RS12260 H NADH ammonium 2-oxoglutarate a peptide glutamyl)- (6Z,9Z,12Z,15Z,18Z)-3- (6Z,9Z,12Z,15Z,18Z,21Z)-3- a 2-(all-trans- 3,24-dioxocholest- an octanoyl-[acp an N - a cis-delta17-3-[+ 5 isozymes] L-alanyl-D- acyltransferase: C4H07_RS08935 (4Z,7Z,10Z,13Z,16Z,19Z) a ribonucleic acid PII protein 4-(glutathion- (2S)-4-acetamido- an L-glutaminyl- (S)-NADPHX DNA without C4H07_RS12635 biosynthetic 3-methylbut- 6-carboxytetrahydropterin C4H07_RS14135 FabI: fabI amino acid acetyl-CoA oxotetracosapentaenoyl-CoA oxotetracosahexaenoyl-CoA polyprenyl)phenol domain within a methyluracil 1498 reductase FabI: acyl-carrier protein a 3-oxoacyl-[acp] -docosahexaenoyl-CoA S-yl)-fenclorim 4-en-26-oyl-CoA 2-aminobutanoate Gln hydroxyC36:1- lesion glutamate--2, 6- peptidoglycan C4H07_RS17645 [tRNA ] lipid-A-disaccharide 2-enyl- synthase QueD: queD [+ 5 isozymes] enoyl-ACP a 2,3,4-saturated C4H07_RS03235 a trans-2-enoyl- fatty acid synthase] in 16S rRNA [acp] diaminopimelate lipid A disaccharide (P. putida) synthase: transglycosylase: diphosphate reductase FabI: fatty acyl-[acp] [acyl-carrier protein] [+ 3 isozymes] 6-carboxy-5,6,7,8- a (3R)-3- enoyl-ACP ligase MurE/UDP- C4H07_RS12635 tetraacyldisaccharide mtgA synthase: ispG acetyl-CoA C- tetrahydropterin C4H07_RS03235 hexanoyl-CoA α N-acetylmuramoyl- (E)-4-hydroxy-3- hydroxyhexadecanoyl-[acp] reductase a 2,3,4-saturated a 2,3,4-saturated a [2-oxoglutarate- a methylated (2E,6Z,9Z,12Z,15Z,18Z) a peptide with (3R,7Z,10Z,13Z,16Z)-3- (3Z)-hex- a (2E)-hex-2-enoyl- 3-[(4'- 1,6-anhydro-N- -Kdo8N- dCDP lipid A disaccharide 4'-kinase: a nascent peptidoglycan acyltransferase: phosphonoacetaldehyde a 2-oxo 3-phenyl-2- glutathione 2-hydroxyisobutyramide a cis-delta15-3- MeOH tripeptide--D- methylbut-2-en- 7-carboxy-7- FabI: fabI fatty acyl CoA 3-oxoacyl-CoA dehydrogenase a sulfurated nucleobase 2-oxoglutarate -tetracosahexaenoyl-CoA L-ornithine an N-terminal pimeloyl-CoA ala 3-en-1-ol [acp domain within methylsulfanyl) β (2->6)-lipid IV (E. coli) C4H07_RS05755 with (L-alanyl-γ-D-glutamyl- 3-hydroxyacyl- a stearoyl-[acp] acyl-CoA C4H07_RS17645 SAM carboxylate oxopropanoate hydroxydocosatetraenoyl-CoA acetyl- -muramate A oxo-C34:1-[acp] ribonucleotide- alanyl-D-alanine deazaguanine E2 protein] N 6 - [sulfur carrier] within DNA enoyl-CoA hydratase Xaa-L-proline glutathione S- a fatty acid synthase] butyl]malate anhydro-N- 3-deoxy-D-manno- tetraacyldisaccharide meso-2,6-diaminopimeloyl-D- 1-yl diphosphate ACP dehydratase dehydrogenase: DNA oxidative ornithine--oxo-acid leucyl 8-amino-7- amidase: SDR family diphosphate D-ala lipid IV (P. putida) synthase: queE [+ 3 isozymes] octanoyl-L-lysinelipoyl phosphonoacetaldehyde family protein: 4-hydroxyphenylpyruvate acetoacetyl-CoA transferase: acyl-CoA 3-isopropylmalate acetylmuramic octulosonic catalase: ligase MurF: murF A FabZ: fabZ demethylase transaminase: aminopeptidase: oxononanoate C4H07_RS19220 oxidoreductase: 4'-kinase: alanyl-D-alanine) pentapeptide enoyl-ACP C4H07_RS17655 synthase: hydrolase: C4H07_RS09670 dioxygenase: hppD reductase: phbB synthetase: dehydrogenase: acid kinase: C4H07_RS19890 reductase: 4-hydroxy- 4-hydroxy- 7-carboxy-7- C4H07_RS18325 C4H07_RS01790 C4H07_RS00400 acid kinase: C4H07_RS14135 C4H07_RS05755 reductase FabI: a [2-oxoglutarate AlkB: alkB a peptide with C4H07_RS12145 synthase: bioF [+ 11 isozymes] C4H07_RS02235 leuB C4H07_RS04510 D-alanine--D- deazaguanine [+ 12 isozymes] lipA a nucleobase [+ 7 isozymes] L-glutamate-5- a proteinogenic a proteinogenic 8-amino-7- [+ 5 isozymes] C4H07_RS04650 C4H07_RS11795 UDP-N-acetyl- D-alanyl-D-alanine D-alanyl-D-alanine 3-methylbut- 3-methylbut- a (2E)-hexadec-2-enoyl-[acp] C4H07_RS03235 an unsulfurated dehydrogenase succinate formaldehyde (2-hydroxyphenyl) an N-terminal (7Z,10Z,13Z,16Z)-3- coenzyme A 2-hydroxy-2- a hexanoyl-[acp N-acetyl-D- 4-O-phospho- a cis-delta15-3-[+ 5 isozymes] C4H07_RS04515 alanine ligase: 5'-deoxyadenosine met within DNA acetaldehyde (3S,6Z,9Z,12Z,15Z,18Z)-3- oxononanoate 3-(glutathion-S 7-(methylsulfanyl) formaldehyde α-D-muramoyl- lipid IV (E. coli) carboxypeptidase: carboxypeptidase: 2-enyl 2-enyl 7-cyano-7- trans-hex-2-enoyl-CoA 6 semialdehyde amino acid acetate amino acid oxodocosatetraenoyl-CoA methylpropanoate A stearate enoyl-ACP [sulfur carrier] E2 protein] N hydroxytetracosapentaenoyl-CoA L-proline -yl)-hexan-1-ol domain within a -2-oxoheptanoate muramate 6- α-Kdo8N- hydroxyC34:1- CDP L-alanyl-γ-D- C4H07_RS04325 diphosphate diphosphate deazaguanine enoyl-ACP acetyl-CoA C4H07_RS00540 C4H07_RS00540 a mature peptidoglycan with reductase -lipoyl-L-lysine fatty acid synthase] phosphate (2->6)-lipid IV [acp] glutamyl-meso-2,6- γ reductase: reductase: synthase reductase long-chain fatty enoyl-CoA A D-alanyl-D-alanine 3-deoxy-D-manno- (L-alanyl- -D-glutamyl-meso- FabI: fabI a nascent peptidoglycan a nascent peptidoglycan FabI: fabI hydratase diaminopimelate octulosonic acid 2,6-diaminopimeloyl-D-alanyl- ispH ispH QueC: queC acid--CoA ligase: with (L-alanyl-γ-D-glutamyl- with D,D cross-links (meso- C4H07_RS05530 family protein: a [pyruvate a 5-carboxymethylaminomethyluridine 34 N-acetyl-muramoyl-(L- a peptide with a cytosine 967 (S)-3-hydroxy-(11Z) a (2E)-but-2-enoyl- 3-[(3'- UDP transferase: D-alanine) pentapeptide enoyl-ACP indolylmethylisothiocyanate glutathione a lipid II carboxynorspermidine uroporphyrinogen-III a ribonucleoside a RNA-DNA hybrid a cis-delta13-3- ethanol preQ dehydrogenase a sulfurated Leu alanyl-γ-D-glutamyl-L- VibB coenzyme A an N-terminal [acp domain within methylsulfanyl) bifunctional UDP- meso-2,6-diaminopimeloyl- diaminopimelate containing) 0 reductase FabI: [+ 6 isozymes] C4H07_RS18325 in tRNA in 16S rRNA -octadecenoyl-CoA C4H07_RS00495 phenylacetate Aromatic Compound Degradation SAM 6 5'-monophosphate oxo-C32:1-[acp] ribonucleotide- DMAPP IPP E2 protein] N - [sulfur carrier] glutathione S-transferase: D-alanyl-D-alanine tRNA (cytidine(34) lysyl-D-alanyl-D-alanine) L-proline 16S rRNA a fatty acid synthase] propyl]malate ribonuclease N-acetylmuramoyl- D-alanine) tetrapeptide C4H07_RS03235 [+ 7 isozymes] biphenyl degradation D-alanyl-D-alanine uroporphyrinogen-III prolyl 3-hydroxyacyl-CoA 5'-nucleotidase SDR family diphosphate stearoyl-CoA degradation I (aerobic) octanoyl-L-lysinelipoyl C4H07_RS00400 carboxypeptidase: -2'-O)- holo-ACP synthase: carboxynorspermidine (cytosine(967)-C(5) acyl-CoA 3-isopropylmalate HI: rnhA catalase: L-alanyl-D- α-Kdo-(2->6)- (S)-3- carboxypeptidase: C-methyltransferase: aminopeptidase: pip dehydrogenase: SurE: oxidoreductase: reductase: phosphatidylserine and synthase: [+ 5 isozymes] C4H07_RS00540 methyltransferase: C4H07_RS11375 decarboxylase: nspC )-methyltransferase synthetase: dehydrogenase: C4H07_RS19890 glutamate--2, 6- lipid IV (E. coli) muramoyltetrapeptide a palmitoyl-[acp] hydroxyhexanoyl-CoA a [pyruvate a N-acetylglucosamine--N- N-acetyl-muramoyl-(L-C4H07_RS00540 a holo-[VibB aryl- cobA C4H07_RS08935 C4H07_RS10025 ribonuclease C4H07_RS14135 C4H07_RS04510 A a mature peptidoglycan phosphatidylethanolamine coenzyme A phenylacetate biphenyl lipA C4H07_RS02235 leuB carboxypeptidase: indol-3-ylmethylisothiocyanate-glutathione C4H07_RS02115 3',5'-ADP a peptide pro RsmB: rsmB HII: rnhB diaminopimelate an unsulfurated dehydrogenase D-ala acetylmuramyl-(tetrapeptide) alanyl-γ-D-glutamyl- carrier protein] 967 3-oxo-(11Z)- a butanoyl-[acp [+ 2 isozymes] [+ 5 isozymes] KDO transferase: with D,D cross-links (meso- biosynthesis I 3-hydroxyacyl-CoA phenylacetate-- biphenyl 2,3- 5'-deoxyadenosine met a 5-carboxymethylaminomethyl- D-ala norspermidine precorrin-2 a 5-methylcytosine 6-(methylsulfanyl) a cis-delta13-3- acetaldehyde C4H07_RS04515 a nascent peptidoglycan C4H07_RS08485 a nascent peptidoglycan a mature peptidoglycan 6 a nucleoside 5'- ligase MurE/UDP- [sulfur carrier] E2 protein] N pyrophosphoryl-undecaprenol 34 Leu L-lysyl-D-alanine) octadecenoyl-CoA domain within a a ribonucleoside DNA C4H07_RS00495 diaminopimelate containing) dehydrogenase: CoA ligase: paaF dioxygenase: 2'-O-methyluridine in tRNA in 16S rRNA -2-oxohexanoate monophosphate hydroxyC32:1- dUDP N-acetylmuramoyl- with L,D cross links (meso- LD-carboxypeptidase: with (L-alanyl-γ-D-glutamyl- with (L-alanyl-γ-D-glutamyl- a CDP-diacylglycerol phenylacetyl-CoA -lipoyl-L-lysine fatty acid synthase] α-Kdo-(2->4)-α-Kdo- C4H07_RS08935 cis-3- C4H07_RS02040 [acp] tripeptide--D- diaminopimelate containing) C4H07_RS13975 meso-2,6-diaminopimeloyl- meso-2,6-diaminopimeloyl- CDP-diacylglycerol--serine (2->6)-lipid IV (E. coli) phenylcyclohexa- alanyl-D-alanine A glycine) tetrapeptide D-alanine) tetrapeptide palmitate O-phosphatidyltransferase: 3-oxohexanoyl-CoA a nascent peptidoglycan with pssA 3,5-diene-1,2-diol undecaprenyl-diphospho-N a peptidoglycan RNase III mRNA (9Z,12Z,15Z,18Z,21Z)-3- a peptide with (S)-3- (S)-3-hydroxy-(9Z) a (2E)-dec-2-enoyl- 3-[(5'- a [protein]-L- ligase MurF: murF a 3-sn-phosphatidyl- glutathione glycyl-glycine cis-dienelactone [EntF L-seryl- a phenol an aryl sulfate cis-vaccenoyl-CoA a cis-delta11-3- an aryl sulfate formamide (L-alanyl-γ-D-glutamyl-meso- long-chain fatty acetyl-CoA C- -acetylmuramoyl-L-alanyl-γ- UDP-N-acetyl-α-D-glucosamine dimer (E. faeciums) processing coenzyme A oxotetracosapentaenoyl-CoA an N-terminal hydroxytetradecanoyl- -hexadecenoyl-CoA [acp domain within methylsulfanyl) proline (ω = 180) a mature peptidoglycan L-serine 2-(1,2-epoxy-1,2- carrier protein] oxo-C30:1-[acp] 2,6-diaminopimelate) tripeptide acid--CoA ligase: acyltransferase: D-glutamyl-L-lysyl- D-alanine gamma- D-alanyl-D-alanine substrate D-amino acidS58 family aryl-sulfate CoA a fatty acid synthase] pentyl]malate acyl-CoA peptidylprolyl SDR family acetamidase/ UDP-N-acetyl- with L,D cross-links (meso- a mature peptidoglycan diphenyl ethers undecaprenyldiphospho- ribonuclease III: holo-ACP synthase: 3-hydroxyacyl-CoA 3-hydroxyacyl-CoA 3-isopropylmalate α-Kdo-(2->4)-α- Kdo -(palmitoleoyl) C4H07_RS05530 phosphatidylserine C4H07_RS17645 dihydrophenyl)acetyl-CoA glutamyltransferase: ggt carboxymethylenebutenolidase: carboxypeptidase: acetoacetyl-CoA sulfotransferase: acyl-CoA dehydrogenase: isomerase: sulfatase: formamidase α 2 γ degradation muramoylpentapeptide beta-N- C4H07_RS12200 C4H07_RS11375 peptidase: dehydrogenase: oxidoreductase: -D-muramoyl- Kdo-(2->6)-(lauroyl) -lipid IV diaminopimelate containing) with (L-alanyl- -D-glutamyl- 2-(1,2-epoxy-1,2- C4H07_RS13505 C4H07_RS00540 RNase III a holo-[EntF reductase: phbB C4H07_RS07695 dehydrogenase: synthetase: dehydrogenase: C4H07_RS17655 C4H07_RS10090 C4H07_RS03630 A [+ 6 isozymes] decarboxylase: psd biphenyl-2,3-diol [+ 2 isozymes] C4H07_RS12005 C4H07_RS14135 family protein: L-alanyl-γ-D- meso-2,6-diaminopimeloyl- [+ 3 isozymes] acetylglucosaminyltransferase: γ a peptidoglycan tetramer C4H07_RS08935 C4H07_RS08935 leuB -lipid IV (E. coli) dihydrophenyl) -L-glutamyl- an mRNA fragment processing 3',5'-ADP L-seryl-carrier C4H07_RS02235 [+ 12 isozymes] [+ 2 isozymes] C4H07_RS07560 A murG L-cysteinylglycine D-ala with a D,D cross-link (3R,9Z,12Z,15Z,18Z,21Z)-3- a peptide a D-amino acid a phenol an aryl sulfate 3-oxo-(9Z)- a decanoyl-[acp [+ 5 isozymes] glutamyl-meso-2,6- di-trans,octa-cis a mature peptidoglycan with glycine) tetrapeptide palmitoyl-CoA an L-1- butanoyl-CoA diphenyl ether ditrans,octacis-undecaprenyldiphospho- glycylglycine 2-maleylacetate 3-oxomyristoyl- 8-(methylsulfanyl) (2E,11Z)- a [protein]-L- a cis-delta11-3- a phenol γ acetyl-CoA product mRNA protein] formate diaminopimeloyl- -undecaprenyl (L-alanyl- -D-glutamyl-meso- phosphatidylethanolamine biphenyl 2,3- UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- (Enterococcus faecium) hydroxytetracosapentaenoyl-CoA CoA hexadecenoyl-CoA domain within a -2-oxooctanoate octadecenoyl-CoA proline (ω = 0) hydroxyC30:1- (Kdo) -lipid isomerase: paaB γ D-alanyl-D-alanine phosphate 2 2,6-diaminopimelate) tripeptide acyl-CoA dioxygenase: L-alanyl- -D-glutamyl-L-lysyl-D-alanine fatty acid synthase] [acp] α 2-oxepin-2(3H)- 2-hydroxy-6-oxo- -D-Kdo-(2->4) A, cold adapted dehydrogenase: (1S,2S)-3-C4H07_RS02040 α ylideneacetyl-CoA 6-phenylhexa- - -D-Kdo-(2->6) C4H07_RS17655 phenoxycyclohexa- 2503 a 3-methyl-branched 3S-(4-hydroxyphenyl) 3-[(6'- -lipid A (E. coli) 2,4-dienoate adenine 5,10-methylene- 3-methyl-2- UDP-N-acetyl-α-D-muramoyl-L- (9Z,12Z,15Z,18Z)-3- Nα,Nε-diacetyl-lysyl- a dipetide with an N- 1-carboxyvinyl (7Z)- (5Z)- an adenosine 34 [+ 12 isozymes] 3,5-diene-1,2-diol 2,3,4-saturated 2-oxoglutarate an apo [peptidyl- an apo-[aryl- -3-hydroxy- acetoacetyl-CoA methylsulfanyl) a cis-delta19-3- maleate in 23S rRNA tetrahydromethanopterin oxobutanoate alanyl-γ-D-glutamyl-meso-2,6- coenzyme A coenzyme A oxotetracosatetraenoyl-CoA D-alanyl-D-alanine terminal L-aspartate carboxyphosphonate tetradecenoyl-CoA dodecenoyl-CoA in [tRNA Arg2 ] undecaprenyldiphospho- carrier protein] carrier protein] hexyl]malate acyl-CoA acyl-CoA oxo-C38:1-[acp] crotonyl-CoA 23S rRNA 3-methyl-2-oxobutanoate diaminopimeloyl-D-alanyl-D-alanineD-alanyl-D-alanine fatty acyl-CoA phytanoyl-CoA D-alanyl-D-alanine dipeptidase: propanoyl-CoA oxaloacetate 3-hydroxyacyl-CoA SDR family tRNA N-acetylmuramoyl-L- 3-oxo-5,6-didehydrosuberyl- protocatechuate degradation holo-ACP synthase: holo-ACP synthase: acetoacetyl-CoA 3-hydroxyacyl-CoA 3-isopropylmalate dehydrogenase: dehydrogenase: maleate isomerase: 2,6-dioxo-6- (adenine(2503)-C(2) hydroxymethyltransferase: carboxypeptidase: dioxygenase: carboxypeptidase: C4H07_RS07060 decarboxylase: dehydrogenase oxidoreductase: adenosine(34) alanyl-γ-D-glutamyl-meso CoA semialdehyde II (ortho-cleavage pathway) C4H07_RS11375 C4H07_RS11375 reductase: phbB dehydrogenase: dehydrogenase: C4H07_RS17655 C4H07_RS17655 C4H07_RS02015 enoyl-CoA phenylhexa- diphenyl )-methyltransferase panB C4H07_RS00540 a 2-hydroxy-3-methyl-C4H07_RS01280 C4H07_RS00540 a proteinogenic C4H07_RS16115 family protein: C4H07_RS14135 deaminase -2,6-diaminopimeloyl- UDP-N-acetylmuramoyl-L- a holo [peptidyl- a holo-[aryl- α ε asp C4H07_RS08935 leuB hydratase ether 2,3-diol RlmN: rlmN THMPT 2-dehydropantoate 3',5'-ADP 3',5'-ADP N ,N -diacetyl- amino acid C4H07_RS18800 [+ 12 isozymes] [+ 12 isozymes] TadA: tadA 3-enoate protocatechuate D-ala alanyl-γ-D-glutamyl-meso-2,6- succinate branched 2,3,4- carrier protein] carrier protein] (3R,9Z,12Z,15Z,18Z)-3- D-ala 3-(hydroxyphosphinoyl) (S)-3- a cis-delta19-3-[+ 5 isozymes] 34 D-alanyl-D-alanine 2503 lysyl-D-alanine 3-(4-hydroxyphenyl)- 9-(methylsulfanyl) (2E,7Z)- (2E,5Z)- fumarate an inosine family protein: a 2-methyladenine saturated fatty acyl-CoA hydroxytetracosatetraenoyl-CoA pyruvate undecaprenyldiphospho- 5'-deoxyadenosine met diaminopimeloyl-D-alanine 3-oxo-propanoyl-CoA hydroxybutanoyl- -2-oxononanoate tetradecenoyl-CoA dodecenoyl-CoA hydroxyC38:1- in [tRNA Arg2 ] C4H07_RS18325 in 23S rRNA muramoylpentapeptide beta-N- 3-oxo-5,6- CoA [acp] acetylglucosaminyltransferase: [+ 7 isozymes] didehydrosuberyl-CoA (2Z,4E)-2- 3-carboxy-cis,cis-muconate benzoate murG (S)-3- hydroxy-6-oxo- 3-oxo-5,6- decaprenyl-diphospho-N- UDP-N-acetyl- 5-amino-4- a peptidoglycan an N-terminal-L-methionyl- (R)-N-formyl-β- (S)-3-hydroxy-(7Z) D-sedoheptulose RNase G 3,22-dioxochol- (3R)-3- lipid II (meso hydroxybutanoyl-CoA 6-phenoxyhexa- PRPP aci-nitroethane an L-arginyl- an N-terminal L- [EntB aryl- (3S)-3-hydroxy- meso-tartrate wound RNA dehydrosuberyl- acetylmuramoyl-pentapeptide α-D-glucosamine DL-allothreonine coenzyme A dimer (S. aureus) L-cysteinyl-[protein] hydroxy-L-kynurenine 2-oxoglutarate D-ala 1-phosphate degradation 4-en-24-oyl-CoA hydroxybutanoyl- imidazolecarboxyamide Arg -tetradecenoyl-CoA L-aspartate diaminopimelate 3-hydroxyacyl-CoA 2,4-dienoate undecaprenyldiphospho- nitronate [tRNA ] glutamyl-[protein] carrier protein] D-alanyl-D-alanine type I methionyl arylformamidase: fructose- substrate mRNA ATP- CoA adenine serine D-amino-acid 3-hydroxyacyl-CoA acetyl-CoA C- CoA threo-3-hydroxy- tartrate containing) dehydrogenase: (2-carboxy-2,5-dihydro- muramoylpentapeptide beta-N- monooxygenase: arginyltransferase: holo-ACP synthase: carboxypeptidase: aminopeptidase: kynB bisphosphate enoyl-CoA dependent thiolase: pcaF phosphoribosyltransferase: hydroxymethyltransferase: transaminase: dehydrogenase: ribonuclease G: acyltransferase: L-aspartate dehydrogenase: C4H07_RS08935 5-oxofuran-2-yl)-acetate acetylglucosaminyltransferase: C4H07_RS02780 an N-terminal C4H07_RS16730 C4H07_RS11375 C4H07_RS00540 map β aldolase class II: hydratase: RNA helicase C4H07_RS18540 C4H07_RS04675 [unspecified (R)- -hydroxy- C4H07_RS15865 C4H07_RS08935 C4H07_RS11635 C4H07_RS01465 ammonia-lyase: C4H07_RS09595 trans-2,3-dehydroadipyl-coA 2-pyrone-6- Arg a holo-[EntB aryl- a peptidoglycan formate C4H07_RS00750 phenol 4-carboxymuconolactone murG AICAR L-arginiyl-L- a tRNA 3',5'-ADP an N-terminal L- L-kynurenine C4H07_RS07575 [+ 3 isozymes] DbpA: dbpA acetoacetyl-CoA carboxylate decaprenyl-pyrophosphoryl- gly acetaldehyde degradation nitrite acetaldehyde carrier protein] D-ala with D,D cross- met pyruvate D-glt 3-oxo-(7Z)- C4H07_RS16560 2-hydroxy-3- glutamyl-[protein] cysteinyl-[protein] 3-oxo-4-pregnene- crotonyl-CoA enoyl-CoA decarboxylase: UDP (N-acetylglucosamine)-N- products] link (S. aureus) tetradecenoyl-CoA D-erythrose DHAP an mRNA fragment oxaloacetate oxosuccinate an unwound RNA acetyl-CoA C- 20-carboxyl-CoA Amine and Polyamine Degradation hydratase/ C4H07_RS18705 acetylmuramyl-(pentapeptide) acyltransferase: isomerase (4,5-dihydro-5- C4H07_RS02450 4-aminobutanoate family protein: oxofuran-2-yl)-acetate β superpathway of 4- 2,5-diamino-6-(5- an sn-glycero-3- a peptidoglycan dimer (meso N-acetyl- -D-glucosamine- an N-terminal-L-methionyl- a 5-aminomethyl-2- 4-bromodiphenyl a [protein]- urea degradation II [+ 5 isozymes] C4H07_RS02285 anthranilate an L-arginyl- an N-terminal L- AsbD acyl- glycochenodeoxycholate γ-L-glutamyl-(S)- a double-stranded aminobutanoate degradation degradation III phospho-D-ribitylamino) 1,6-anhydro-N- uroporphyrinogen-I 4-guanidinobutyramide 34 (R)-glycerate 3-oxoadipate enol- phospho-N-(acyl) -diaminopimelate containing) Arg coenzyme A L-threonyl-[protein] gly oligonucleotide thiouridine in tRNA fMet ether L-glutamine degradation β [tRNA ] aspartyl-[protein] carrier protein 2-aminobutanoate biotin ATP acetyl-CoA [+ 7 isozymes] lactonase: pcaD pyrimidin-4(3H)-one ethanolamine D-alanyl-D-alanine acetyl- -D-muramate linear amide C- type I methionyl uroporphyrinogen tRNA 2- peptide biphenyl 2,3- chemoreceptor 4-aminobutanoate I (aerobic) bifunctional glycerophosphodiester beta-N- arginyltransferase: holo-ACP synthase: glutathione amidase: 4-aminobutanoate urea carboxypeptidase: N hydrolase: aminopeptidase: oligoribonuclease: biotin--[acetyl-CoA- thiouridine(34) glycerate kinase: glutamine (3S)-hydroxyadipyl-CoA diaminohydroxyphosphoribosylaminopyrimidine phosphodiesterase: ugpQ acetylhexosaminidase: C4H07_RS16730 C4H07_RS11375 synthase: gshB decarboxylase: C4H07_RS19220 deformylase: dioxygenase: 4-aminobutyrate- 4-aminobutyrate- urease: anthranilate 3-oxoadipate C4H07_RS00540 an N-terminal C4H07_RS17510 map C4H07_RS06150 carboxylase] ligase: synthase C4H07_RS16165 deaminase/5-amino-6-(5-phosphoribosylamino) sn-glycerol an N- a peptidoglycan with nagZ a holo-[AsbD acyl- C4H07_RS02855 [+ 11 isozymes] C4H07_RS01870 C4H07_RS02040 deamidase -2-oxoglutarate -2-oxoglutarate C4H07_RS03455 1,6-anhydro-N- L-arginiyl-L- a tRNA Arg 3',5'-ADP an N-terminal L- ophthalmate C4H07_RS00510 MnmA: mnmA 4-bromo-2,3- 3-hydroxyacyl-CoA uracil reductase RibD: ribD 3-phosphate acylethanolamine D-ala D,D cross-links (meso- GlcNAc carrier protein] gly chenodeoxycholate met a nucleoside 5'- biotinyl-5'- formate met 3-phospho- CheD: cheD transaminase: transaminase: C4H07_RS03465 acetyl-β-muramate aspartyl-[protein] threonyl-[protein] coproporphyrinogen I 4-guanidinobutanoate a 5-methylaminomethyl- a [protein]-α- dehydrogenase: 5-amino-6-(5-phospho- adenylate dihydrodiol- D-glycerate diaminopimelate containing) monophosphate 2-thiouridine 34 in tRNA L-glutamate gabT gabT ureC C4H07_RS08935 D-ribitylamino)uracil diphenyl ether ammonium catechol 4-aminobutyrate- 4-aminobutyrate- -2-oxoglutarate -2-oxoglutarate 3-oxoadipyl-CoA a mature peptidoglycan a 2,3,4-saturated (25S)-3- CDP-4-dehydro-3,6- a 2,3,4-saturated (n) a single- 3-aci- an apo-[LYS2 L- an N-terminal (2R,3S)-3- transaminase: transaminase: an L-arginyl- an N-acylated- canavaninosuccinate (S)-3-hydroxy-(5Z) (+)-muconolactone a folate 2-chloroacetate pyrazinamide malonyl-CoA (meso-DAP containing) CTP 1,2-diacyl-sn- 2-aminoadipyl- coenzyme A 3-sulfino-L- oxocholest- coenzyme A dideoxy-α-D-glucose (3S)-3- C4H07_RS09140 C4H07_RS09140 3-oxoadipyl-CoA stranded RNA nitropropanoate [tRNA Arg ] D-amino acid -dodecenoyl-CoA isopropylmalate succinate succinate C1 Compound Utilization and Assimilation lytic transglycosylase polyribonucleotide nitronate glycerol 3-phosphate carrier-protein] 4-en-26-oate CDP-6-deoxy-delta- hydroxyacyl-CoA haloacid thiolase: pcaF phosphatidate holo-ACP synthase: alanyl-[protein]arginyltransferase: D-aminoacylase: acyl-CoA argininosuccinate 3-hydroxyacyl-CoA muconolactone dihydrofolate 3-isopropylmalate amidase: malonyl-CoA semialdehyde semialdehyde domain-containing nucleotidyltransferase: pnp monooxygenase: 3,4-glucoseen 3-hydroxyacyl-CoA dehalogenase cytidylyltransferase: C4H07_RS11375 C4H07_RS16730 C4H07_RS13765 synthetase: lyase: argH dehydrogenase: Delta- reductase: dehydrogenase: C4H07_RS19220 decarboxylase: protein: C4H07_RS03970 a nucleoside a single- C4H07_RS02780 a holo-[LYS2 L- an N-terminal L- reductase: dehydrogenase: NAD-dependent NAD-dependent succinyl-CoA formaldehyde oxidation [unspecified C4H07_RS12675 (25S)-3-C4H07_RS02235 fumarate L-canavanine C4H07_RS08935 isomerase: catC C4H07_RS03535 leuB type II: [+ 11 isozymes] C4H07_RS11455 formaldehyde oxidation [+ 2 isozymes] diphosphate stranded RNA a CDP-2,3,4-saturated- 2-aminoadipyl- 3',5'-ADP arginiyl-3-sulfino- a tRNA Arg a carboxylate a D-amino acid C4H07_RS10530 C4H07_RS08935 NAD-dependent succinate- succinate- VII (THF pathway) degradation nitrite 3-oxopropanoate oxocholest-4- CDP-4-dehydro-6- 3-oxo-(5Z)- (4,5-dihydro-5- 4-methyl-2- C4H07_RS09350 pyrazine-2- II (glutathione-dependent) GlcNAc-1,6-anhMurNAc- a mature peptidoglycan a 2,3,4-saturated a 7,8-dihydrofolate acetyl-CoA (n) diacylglycerol carrier-protein] L-alanyl-[protein] glycolate succinate- semialdehyde semialdehyde L-Ala-γ-D-Glu-DAP-D-Ala (meso-DAP containing) products] en-26-oyl-CoA deoxy-α-D-glucose dodecenoyl-CoA 3-oxoacyl-CoA oxofuran-2-yl)-acetate oxopentanoate carboxylate semialdehyde dehydrogenase: dehydrogenase: formaldehyde formaldehyde dehydrogenase: C4H07_RS15925 C4H07_RS09135 an N-acetyl-β- C4H07_RS01180 NAD-dependent NAD-dependent phosphatidylglycerolphosphate sn-glycero-3- phosphoenol an [HPr]- an N-terminal acibenzolar- 3-[(7'-methylsulfanyl) a myo-inositol a monocarboxylic a peptide with a 5,10- an L-arginyl- an L-arginyl- butanoyl-CoA phosphate a protein with a thiopurine Ins(4)P DHAP acetamide [+ 2 isozymes] phosphoethanolamine L-histidine O-acetyl-L-serine hydrogen selenide D-hexosaminide Arg 3-sulfo-L- Arg a protein glutathione an N-terminal succinate- succinate- S-(hydroxymethyl) (1-oleoyl, 2-palmitoyl) pyruvate [tRNA ] [tRNA ] S-methyl a disulfide bond heptyl]malate monophosphate acid amide methylenetetrahydrofolate glycerophosphodiester phosphoenolpyruvate- beta-N- alanyl-[protein] phosphate S-formylglutathione L-methionine semialdehyde semialdehyde glutathione cysteine synthase arginyltransferase: arginyltransferase: glutaredoxin 3-isopropylmalate inositol amidase: type I methionyl thiopurine S- inositol methylglyoxal amidase: bifunctional phosphatidylglycerophosphatase phosphodiesterase: ugpQ -protein acetylhexosaminidase: acetyltransferase: hydrolase: fghA dehydrogenase: dehydrogenase: S-(hydroxymethyl) CysM: cysM C4H07_RS16730 C4H07_RS16730 3: grxC dehydrogenase: monophosphatase: C4H07_RS19220 aminopeptidase: methyltransferase: monophosphatase: synthase: C4H07_RS16100 sn-glycerol phosphotransferase: ptsP nagZ an N-terminal L- a protein with C4H07_RS15925 methylenetetrahydrofolate A: C4H07_RS16960 an [HPr protein]- C4H07_RS14775 MeOH acibenzolar leuB [+ 11 isozymes] map C4H07_RS15330 C4H07_RS10480 [+ 11 isozymes] C4H07_RS09135 glutathione ethanolamine an N-acetyl-β- Arg an N-terminal Arg C4H07_RS08855 C4H07_RS08855 dehydrogenase/ 3-phosphate π acetate L-selenocysteine an alcohol arginiyl-3-sulfo- a tRNA a tRNA butanoyl reduced L- GSSG dehydrogenase/ 1-oleoyl-2-palmitoyl- N -phospho- pyruvate D-hexosamine arginyl-[protein] 10-(methylsulfanyl) a peptide met a thiopurine succinate methenyltetrahydrofolate L-alanyl-[protein] phosphate cysteine residues myo-inositol a monocarboxylate myo-inositol methylglyoxal acetate succinate class III alcohol phosphatidylglycerol L-histidine -2-oxodecanoate S-methylether cyclohydrolase FolD: folD dehydrogenase: bifunctional C4H07_RS19380 methylenetetrahydrofolate a [glycine-cleavage sn-glycero-3- 7,8-dihydrofolate 4-nitrophenyl 2-aryl-2- an N 1 -ethyladenine in DNA 2-oxoglutarate PRPP H + phytanoyl-CoA 2-oxoglutarate chitin (S)-2- NADH H + A 4-nitrocatecholsulfate L-tartrate γ-L-glutamyl- SAM complex H protein] a sulfurated [sulfur carrier] phospho-N- nicotinate NADPH glu H O diphosphate L-threo-3-phenylserine a cytosine in DNA Ins(5)P gly dehydrogenase/ S-formylglutathione monoglutamate aminobutanoate butanoate 2 methylmalonate D-alanine N 6 -octanoyl-L-lysine DNA oxidative (arachidonoyl) nicotinate dihydrofolate phytanoyl-CoA beta-N- arylesterase: NADH inorganic methenyltetrahydrofolate lipoyl glutamate-- low-specificity hypothetical inositol tartrate glutathione demethylase AlkB: alkB ethanolamine phosphoribosyltransferase: reductase: dioxygenase: acetylhexosaminidase: C4H07_RS10095 dehydrogenase: diphosphatase: sulfatase: DNA methylase: cyclohydrolase FolD: folD S-formylglutathione synthase: lipA glycerophosphodiester cysteine ligase: L-threonine protein: monophosphatase: dehydrogenase: synthase: a [glycine-cleavage pncB C4H07_RS03535 C4H07_RS01280 nagZ C4H07_RS16975 C4H07_RS06980 C4H07_RS03630 C4H07_RS03735 a 5,10- hydrolase: fghA an unsulfurated succinate acetaldehyde an adenine in DNA phosphodiesterase: ugpQ N-acetyl-D- C4H07_RS02100 butanoate 4-nitrophenol aldolase: ltaE C4H07_RS17010 C4H07_RS08855 C4H07_RS09595 gshB 5'-deoxyadenosine met complex H protein] sn-glycerol + 5,6,7,8- 2-hydroxyphytanoyl- γ-L-glutamyl-(S)- + anandamide NaMN NADP succinate chitin A(H2) NAD phosphate H + a 5-methylcytosine 2-hydroxy-3- norophthalmate methenyltetrahydrofolate [sulfur carrier] 6 tetrahydrofolate CoA glucosamine 4-nitrocatechol gly benzaldehyde 2-arylpropanoate formate N -lipoyl-L-lysine 3-phosphate 2-aminobutanoate in DNA myo-inositol oxosuccinate bifunctional methylenetetrahydrofolate dehydrogenase/ formate (2S,3S)-2,3- 37 RNase R degradation an N-acyl- 1-deoxy-D-xylulose 3 an adenosine methyl (indol- + + β a supercoiled methenyltetrahydrofolate oxidation to CO a thiocarboxy- an N -methylcytosine in DNA 2-oxoglutarate DMAPP glycerophosphoserine a ribonucleic acid hydrogencarbonate H FMNH NADP dihydroxy-5- 3-methylmuconolactone -citryl-L- Ins(6)P glutaryl-CoA sec 2 2-iminoacetate 2 D-glutamate L-allo-threonine a tRNA ser 5-phosphate [ThiS-Protein] in tRNA substrate RNA 3-yl)acetate glutamate duplex DNA Nucleoside and Nucleotide Degradation cyclohydrolase FolD: folD DNA oxidative glycerophosphodiester ribonuclease ribonuclease PH: S-formylglutathione carbonic flavin reductase: D-aminoacylase: oxohexanedioate thiazole synthase: tRNA (adenosine(37)-N6) 2-dehydro-3- muconolactone N-formylglutamate ATP-dependent low-specificity inositol acyl-CoA serine--tRNA formate demethylase AlkB: alkB phosphodiesterase: ugpQ R: rnr C4H07_RS07930 hydrolase: fghA anhydrase: C4H07_RS03045 C4H07_RS13765 bifunctional C4H07_RS01315 -dimethylallyltransferase deoxyglucarate Delta- deformylase: hutG DNA helicase Rep: L-threonine monophosphatase: dehydrogenase: ligase: serS formaldehyde formate 2-[(2R,5Z)-2-carboxy- a nucleoside 5'- a nucleoside C4H07_RS16535 inosine 5'-phosphate methylenetetrahydrofolate succinate formaldehyde a cytosine in DNA MiaA: miaA sn-glycerol a diribonucleotide a ribonucleic acid MeOH (indol-3-yl)acetate H + NADPH FMN aldolase: garL isomerase: catC C4H07_RS02845 aldolase: ltaE C4H07_RS07665 thymine degradation UTP and CTP dephosphorylation I pseudouridine oxidation IV (thiol- dehydrogenase a ThiS sulfur- N 6 -dimethylallyladenosine 37 ser D-glt a carboxylate C4H07_RS08855 sec degradation dehydrogenase/ 4-methylthiazol-5(2H)- 3-phosphate monophosphate diphosphate H O CO tartronate citrate glu an L-seryl-[tRNA ] 2 2 pyruvate 4-methyl-3-oxoadipate- a single acetaldehyde degradation independent) subunit gamma: carrier protein in tRNA semialdehyde gly crotonyl-CoA methenyltetrahydrofolate ylidene]ethyl phosphate enol-lactone stranded DNA myo-inositol thymine UTP C4H07_RS12395 cyclohydrolase FolD: folD formaldehyde IMP pseudouridine CO aldehyde 2 IMP CTP synthase: a 10- 5,6-dihydrothymine an (S-diacyl-sn- a peptide with CTP formyltetrahydrofolate dehydrogenase an L-1- + 3,4-dihydroxyphenylacetyl- S-(2-hydroxyacyl) a single a ribonucleoside all-trans- (-)-methyl 4-nitrophenyl + 5-dehydro-4- β dehydrogenase: C4H07_RS11985 glyceryl)-L-cysteinyl- acetyl-CoA malonyl-CoA NADPH H glycerophosphoglycerol FMN NADH H L-canavanine -citryl-L- glycocholate 3-ethylmalate nitric oxide pseudouridine family protein: phosphatidylethanolamine CoA glutathione stranded DNA triphosphate retinyl palmitate jasmonate palmitate deoxy-D-glucarate an N-terminal guaB hydantoinase/ UDP formyltetrahydrofolate [apolipoprotein] hydroxyphenylacetyl- glycerophosphodiester 2-dehydro-3- arginase: glutamine linear amide C- C4H07_RS18065 apolipoprotein N- acyl-CoA synthetase: hydroxyacylglutathione DNA primase: S-formylglutathione S-formylglutathione arylesterase: flavin reductase: L-alanine 3-isopropylmalate NO-inducible dCTP deaminase: XMP oxoprolinase CTP 5'-phosphate deformylase: purU N-formylglutamate N hydrolase: aminopeptidase C4H07_RS02235 CoA thioesterase phosphodiesterase: ugpQ hydrolase: gloB C4H07_RS10790 hydrolase: fghA hydrolase: fghA C4H07_RS10095 C4H07_RS03045 deoxyglucarate C4H07_RS07635 dehydrogenase: flavohemoprotein: C4H07_RS18940 family protein: aldehyde acyltransferase: lnt deformylase: hutG N: pepN formyltetrahydrofolate an N-acyl-(S-diacyl- PaaI: paaI sn-glycerol a 2-hydroxy ssDNA/pppN(pN) + aldolase: garL C4H07_RS17510 tRNA dehydrogenase: a 2-acyl-1-lyso- a long-chain acyl-CoA glycerol glutathione palmitate all-trans-retinol MeOH (-)-jasmonate palmitate 4-nitrophenol NAD FMNH arginase: rocF leuB hmpA 5'-3'- C4H07_RS15520 deformylase: purU sn-glyceryl)-L- (3,4-dihydroxyphenyl) 3-phosphate carboxylate hybrid 2 tartronate citrate gln a peptide ala UTP pseudouridine(55) phosphatidylethanolamine coenzyme A n -1 pyruvate gly cholate deoxyribonucleotidase: UMP C4H07_RS10955 cysteinyl-[lipoprotein] acetate semialdehyde urea L-canaline 2-oxovalerate nitrate hydantoinase/ CDP synthase TruB: truB C4H07_RS18395 formate formate oxoprolinase 5'-3'- RluA family [+ 2 isozymes] family protein: deoxyribonucleotidase: pseudouridine C4H07_RS15950 dCTP C4H07_RS18395 synthase: 1 (2-hydroxyphenyl)methyl 1-hydroxy- a peptidoglycan 7,8- an all-trans + all-trans- O-ureido-L- a kanamycin an organic xanthosine an N -methyladenine in DNA 2-oxoglutarate (2S)-methylsuccinyl-CoA acetyl-CoA a carboxylic ester FMN NAD(P)H H methylsalicylate asp a phenyl acetate glu ala phenyl acetate carbonic acid CMP [+ 2 isozymes] C4H07_RS14075 6-oxocyclohex-2-ene-1-carboxylate dihydromonapterin -retinyl ester retinyl palmitate homoserine molecule 3-(carbamoylamino)- DNA oxidative S-formylglutathione lysozyme: 3-oxoadipyl-CoA dihydroneopterin S-formylglutathione S-formylglutathione flavin reductase: S-formylglutathione aminoglycoside arylesterase: arylesterase: carbonic dCTP deaminase: adenosine S-formylglutathione argininosuccinate glutamate-- 2-methylpropanoate 5'-3'- uridine uracil demethylase AlkB: alkB hydrolase: fghA C4H07_RS16300 thiolase: pcaF aldolase: folB hydrolase: fghA hydrolase: fghA C4H07_RS03045 hydrolase: fghA phosphotransferase: C4H07_RS10095 C4H07_RS10095 anhydrase: cytochrome P450: C4H07_RS18940 nucleotides a N-acetylmuramoyl- hydrolase: fghA synthase: argG cysteine ligase: deoxyribonucleotidase: 1-hydroxy-6-oxocyclohex- N-acetyl-D- 6-(hydroxymethyl) C4H07_RS16535 C4H07_RS12065 degradation III succinate formaldehyde an adenine in DNA salicyl alcohol 4-methyl-3-oxoadipyl-CoA glycolaldehyde a fatty acid all-trans-retinol a carboxylate an alcohol NAD(P) + FMNH palmitate a retinol MeOH salicylate C4H07_RS16145 acetate a phenol C4H07_RS02100 acetate phenol pentapeptide- 2 canavaninosuccinate C4H07_RS18395 2-ene-1-carboxylate glucosamine -7,8-dihydropterin a kanamycin γ-L-glutamyl- CO H O dUTP diphosphoundecaprenol 2 2 [+ 2 isozymes] 3'-phosphate D-alanine an alcohol xanthine (R)-3-amino-2- AMP cytidine methylpropanoate AMP nucleosidase: C4H07_RS07905 adenine urate

sn-glycerol an amino an amino an amino an amino an amino an amino G 3-phosphate a C4- sucrose 6 -phosphate a polyamine (2-aminoethyl) molybdate acid acid acid acid acid acid alcaligin a branched- maltose 6'-phosphate phosphonate phosphonate a carbohydrate dicarboxylate an amino an amino an amino an amino glutamate glycine betaine phosphonate chain D-mannose D-mannose a C4- 3,5- a lyso- an [HPr]- an [HPr]- an L-sorbose 1-phosphate a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a siderophore a nucleotide molybdate a dipeptide a dipeptide a lipopolysaccharide a tricarboxylate a tricarboxylate benzoate a polysaccharide acid acid acid a capsular 6-phosphate a carbohydrate a carbohydrate dicarboxylate N-acetyl-α-D- phospholipid pyrimidine L-histidine acid [+ 17 more] cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA L-proline betaine phosphite amino acid 6-phosphate a lipopolysaccharide a lipopolysaccharide a lipopolysaccharide chromate dimethoxytoluene L-histidine cis-vaccenoyl-CoA cis-vaccenoyl-CoA polysaccharide predicted glucosamine predicted predicted predicted predicted predicted predicted predicted predicted ABC ABC predicted ABC predicted predicted ABC predicted ABC predicted ABC ABC ABC ABC ABC ABC ABC ABC transporter of transporter transporter ABC RS07155 RS17750 RS11485 RS16925 RS08120 RS14305 transporter of RS07480 RS02590 transporter of RS05420 RS00625 RS18690 RS03870 RS12025 RS16825 RS02605 RS12140 efflux transporter of RS18245 RS12165 RS04145 RS16870 RS09075 RS04840 RS14930 RS17325 RS09705 RS08105 RS07530 RS02590 RS02590 RS14295 transporter transporter transporter transporter transporter transporter RS08625 RS01900 RS02590 RS02235 RS14285 RS15820 RS05195 RS05530 RS03075 RS01755 RS07365 transporter (2-aminoethyl) of sn- of a C4- transporter phosphonate a carbohydrate a lipopolysaccharide of an of an of an of an of an of an of a polyamine phosphonate glycerol 3- dicarboxylate of molybdate amino acid amino acid amino acid amino acid amino acid amino acid glycine betaine phosphonate a branched- phosphate a C4- 3,5- a lyso- pyrimidine 2-deoxy- sucrose a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a nucleotide D-mannose D-mannose a carbohydrate a carbohydrate molybdate a dipeptide a dipeptide a tricarboxylate a tricarboxylate benzoate N-acetyl-α-D- a polysaccharide an amino D-mannopyranose an amino an amino an amino glutamate L-proline betaine phosphite a capsular chain dicarboxylate a lipopolysaccharide a lipopolysaccharide a lipopolysaccharide dimethoxytoluene phospholipid D-glucose maltose cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate a siderophore (2-aminoethyl) phosphonate a carbohydrate a C4- glucosamine chromate acid acid acid acid a polyamine polysaccharide amino acid L-sorbose molybdate a lipopolysaccharide an amino an amino an amino an amino alcaligin phosphonate sn-glycerol dicarboxylate an amino an amino [+ 17 more] acid acid acid acid 3-phosphate acid acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.