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At Least in Biophysical Novelties Amihud Gilead
The Twilight of Determinism: At Least in Biophysical Novelties Amihud Gilead Department of Philosophy, Eshkol Tower, University of Haifa, Haifa 3498838 Email: [email protected] Abstract. In the 1990s, Richard Lewontin referred to what appeared to be the twilight of determinism in biology. He pointed out that DNA determines only a little part of life phenomena, which are very complex. In fact, organisms determine the environment and vice versa in a nonlinear way. Very recently, biophysicists, Shimon Marom and Erez Braun, have demonstrated that controlled biophysical systems have shown a relative autonomy and flexibility in response which could not be predicted. Within the boundaries of some restraints, most of them genetic, this freedom from determinism is well maintained. Marom and Braun have challenged not only biophysical determinism but also reverse-engineering, naive reductionism, mechanism, and systems biology. Metaphysically possibly, anything actual is contingent.1 Of course, such a possibility is entirely excluded in Spinoza’s philosophy as well as in many philosophical views at present. Kant believed that anything phenomenal, namely, anything that is experimental or empirical, is inescapably subject to space, time, and categories (such as causality) which entail the undeniable validity of determinism. Both Kant and Laplace assumed that modern science, such as Newton’s physics, must rely upon such a deterministic view. According to Kant, free will is possible not in the phenomenal world, the empirical world in which we 1 This is an assumption of a full-blown metaphysics—panenmentalism—whose author is Amihud Gilead. See Gilead 1999, 2003, 2009 and 2011, including literary, psychological, and natural applications and examples —especially in chemistry —in Gilead 2009, 2010, 2013, 2014a–c, and 2015a–d. -
Philosophy of Science and Philosophy of Chemistry
Philosophy of Science and Philosophy of Chemistry Jaap van Brakel Abstract: In this paper I assess the relation between philosophy of chemistry and (general) philosophy of science, focusing on those themes in the philoso- phy of chemistry that may bring about major revisions or extensions of cur- rent philosophy of science. Three themes can claim to make a unique contri- bution to philosophy of science: first, the variety of materials in the (natural and artificial) world; second, extending the world by making new stuff; and, third, specific features of the relations between chemistry and physics. Keywords : philosophy of science, philosophy of chemistry, interdiscourse relations, making stuff, variety of substances . 1. Introduction Chemistry is unique and distinguishes itself from all other sciences, with respect to three broad issues: • A (variety of) stuff perspective, requiring conceptual analysis of the notion of stuff or material (Sections 4 and 5). • A making stuff perspective: the transformation of stuff by chemical reaction or phase transition (Section 6). • The pivotal role of the relations between chemistry and physics in connection with the question how everything fits together (Section 7). All themes in the philosophy of chemistry can be classified in one of these three clusters or make contributions to general philosophy of science that, as yet , are not particularly different from similar contributions from other sci- ences (Section 3). I do not exclude the possibility of there being more than three clusters of philosophical issues unique to philosophy of chemistry, but I am not aware of any as yet. Moreover, highlighting the issues discussed in Sections 5-7 does not mean that issues reviewed in Section 3 are less im- portant in revising the philosophy of science. -
5. Essence and Natural Kinds: When Science Meets Preschooler Intuition1 Sarah-Jane Leslie
978–0–19–954696–1 05-Gendler-Hawthorne-c05-drv Gendler (Typeset by SPi) 108 of 346 February 5, 2013 6:20 OUP UNCORRECTED PROOF – FIRST PROOF,5/2/2013, SPi 5. Essence and Natural Kinds: When Science Meets Preschooler Intuition1 Sarah-Jane Leslie INTRODUCTION It is common practice in philosophy to “rely on intuitions” in the course of an argument, or sometimes simply to establish a conclusion. One question that is therefore important to settle is: what is the source of these intuitions? Correspondingly: what is their epistemological status? Philosophical discus- sion often proceeds as though these intuitions stem from insight into the nature of things—as though they are born of rational reflection and judicious discernment. If these intuitions do not have some such status, then their role in philosophical theorizing rapidly becomes suspect. We would not, for example, wish to place philosophical weight on intuitions that are in effect the unreflective articulation of inchoate cognitive biases. Developmental psychology has discovered a range of belief sets that emerge in the first few years of life, and which plausibly go beyond the evidence to which the child has had access in that time period. In such cases, it is reasonable to suppose that the belief sets do not derive solely from the child’s rational reflection on her evidence, but rather show something about the way human beings are fundamentally disposed to see the world. (In some cases, the deep-seated dispositions are also shared with non-human animals.) There are many explanations of why we may be fundamentally disposed to see the world in a particular way, only one of which is that metaphysically or scientifically speaking, the world actually is that way. -
Causality and Determinism: Tension, Or Outright Conflict?
1 Causality and Determinism: Tension, or Outright Conflict? Carl Hoefer ICREA and Universidad Autònoma de Barcelona Draft October 2004 Abstract: In the philosophical tradition, the notions of determinism and causality are strongly linked: it is assumed that in a world of deterministic laws, causality may be said to reign supreme; and in any world where the causality is strong enough, determinism must hold. I will show that these alleged linkages are based on mistakes, and in fact get things almost completely wrong. In a deterministic world that is anything like ours, there is no room for genuine causation. Though there may be stable enough macro-level regularities to serve the purposes of human agents, the sense of “causality” that can be maintained is one that will at best satisfy Humeans and pragmatists, not causal fundamentalists. Introduction. There has been a strong tendency in the philosophical literature to conflate determinism and causality, or at the very least, to see the former as a particularly strong form of the latter. The tendency persists even today. When the editors of the Stanford Encyclopedia of Philosophy asked me to write the entry on determinism, I found that the title was to be “Causal determinism”.1 I therefore felt obliged to point out in the opening paragraph that determinism actually has little or nothing to do with causation; for the philosophical tradition has it all wrong. What I hope to show in this paper is that, in fact, in a complex world such as the one we inhabit, determinism and genuine causality are probably incompatible with each other. -
Some Thoughts About Natural Law
Some Thoughts About Natural Law Phflip E. Johnsont My first task is to define the subject. When I use the term "natural" law, I am distinguishing the category from other kinds of law such as positive law, divine law, or scientific law. When we discuss positive law, we look to materials like legislation, judicial opinions, and scholarly anal- ysis of these materials. If we speak of divine law, we ask if there are any knowable commands from God. If we look for scientific law, we conduct experiments, or make observations and calculations, in order to come to objectively verifiable knowledge about the material world. Natural law-as I will be using the term in this essay-refers to a method that we employ to judge what the principles of individual moral- ity or positive law ought to be. The natural law philosopher aspires to make these judgments on the basis of reason and human nature without invoking divine revelation or prophetic inspiration. Natural law so defined is a category much broader than any particular theory of natural law. One can believe in the existence of natural law without agreeing with the particular systems of natural law advocates like Aristotle or Aquinas. I am describing a way of thinking, not a particular theory. In the broad sense in which I am using the term, therefore, anyone who attempts to found concepts of justice upon reason and human nature engages in natural law philosophy. Contemporary philosophical systems based on feminism, wealth maximization, neutral conversation, liberal equality, or libertarianism are natural law philosophies. -
Scientific Explanation
Scientific Explanation Michael Strevens For the Macmillan Encyclopedia of Philosophy, second edition The three cardinal aims of science are prediction, control, and expla- nation; but the greatest of these is explanation. Also the most inscrutable: prediction aims at truth, and control at happiness, and insofar as we have some independent grasp of these notions, we can evaluate science’s strate- gies of prediction and control from the outside. Explanation, by contrast, aims at scientific understanding, a good intrinsic to science and therefore something that it seems we can only look to science itself to explicate. Philosophers have wondered whether science might be better off aban- doning the pursuit of explanation. Duhem (1954), among others, argued that explanatory knowledge would have to be a kind of knowledge so ex- alted as to be forever beyond the reach of ordinary scientific inquiry: it would have to be knowledge of the essential natures of things, something that neo-Kantians, empiricists, and practical men of science could all agree was neither possible nor perhaps even desirable. Everything changed when Hempel formulated his dn account of ex- planation. In accordance with the observation above, that our only clue to the nature of explanatory knowledge is science’s own explanatory prac- tice, Hempel proposed simply to describe what kind of things scientists ten- dered when they claimed to have an explanation, without asking whether such things were capable of providing “true understanding”. Since Hempel, the philosophy of scientific explanation has proceeded in this humble vein, 1 seeming more like a sociology of scientific practice than an inquiry into a set of transcendent norms. -
Two Concepts of Law of Nature
Prolegomena 12 (2) 2013: 413–442 Two Concepts of Law of Nature BRENDAN SHEA Winona State University, 528 Maceman St. #312, Winona, MN, 59987, USA [email protected] ORIGINAL SCIENTIFIC ARTICLE / RECEIVED: 04–12–12 ACCEPTED: 23–06–13 ABSTRACT: I argue that there are at least two concepts of law of nature worthy of philosophical interest: strong law and weak law . Strong laws are the laws in- vestigated by fundamental physics, while weak laws feature prominently in the “special sciences” and in a variety of non-scientific contexts. In the first section, I clarify my methodology, which has to do with arguing about concepts. In the next section, I offer a detailed description of strong laws, which I claim satisfy four criteria: (1) If it is a strong law that L then it also true that L; (2) strong laws would continue to be true, were the world to be different in some physically possible way; (3) strong laws do not depend on context or human interest; (4) strong laws feature in scientific explanations but cannot be scientifically explained. I then spell out some philosophical consequences: (1) is incompatible with Cartwright’s contention that “laws lie” (2) with Lewis’s “best-system” account of laws, and (3) with contextualism about laws. In the final section, I argue that weak laws are distinguished by (approximately) meeting some but not all of these criteria. I provide a preliminary account of the scientific value of weak laws, and argue that they cannot plausibly be understood as ceteris paribus laws. KEY WORDS: Contextualism, counterfactuals, David Lewis, laws of nature, Nancy Cartwright, physical necessity. -
A Modular Approach to Integrating Multiple Data Sources Into Real-Time Clinical Prediction for Pediatric Diarrhea
RESEARCH ARTICLE A modular approach to integrating multiple data sources into real-time clinical prediction for pediatric diarrhea Ben J Brintz1,2*, Benjamin Haaland3, Joel Howard4, Dennis L Chao5, Joshua L Proctor5, Ashraful I Khan6, Sharia M Ahmed2, Lindsay T Keegan1, Tom Greene1, Adama Mamby Keita7, Karen L Kotloff8, James A Platts-Mills9, Eric J Nelson10,11, Adam C Levine12, Andrew T Pavia4, Daniel T Leung2,13* 1Division of Epidemiology, Department of Internal Medicine, University of Utah, Salt Lake City, United States; 2Division of Infectious Diseases, Department of Internal Medicine, University of Utah, Salt Lake City, United States; 3Population Health Sciences, University of Utah, Salt Lake City, United States; 4Division of Pediatric Infectious Diseases, University of Utah, Salt Lake City, United States; 5Institute of Disease Modeling, Bill and Melinda Gates Foundation, Seattle, United States; 6International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh; 7Centre Pour le De´veloppement des Vaccins-Mali, Bamako, Mali; 8Division of Infectious Disease and Tropical Pediatrics, University of Maryland, Baltimore, United States; 9Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, United States; 10Departments of Pediatrics, University of Florida, Gainesville, United States; 11Departments of Environmental and Global Health, University of Florida, Gainesville, United States; 12Department of Emergency Medicine, Brown University, Providence, United States; 13Division of Microbiology and Immunology, Department of Internal Medicine, University of Utah, Salt Lake City, United States *For correspondence: [email protected] (BJB); [email protected] (DTL) Abstract Traditional clinical prediction models focus on parameters of the individual patient. For infectious diseases, sources external to the patient, including characteristics of prior patients and Competing interests: The authors declare that no seasonal factors, may improve predictive performance. -
Aristotle's Anticommunism Author(S): Darrell Dobbs Source: American Journal of Political Science, Vol
Aristotle's Anticommunism Author(s): Darrell Dobbs Source: American Journal of Political Science, Vol. 29, No. 1 (Feb., 1985), pp. 29-46 Published by: Midwest Political Science Association Stable URL: http://www.jstor.org/stable/2111210 Accessed: 10/12/2010 23:50 Your use of the JSTOR archive indicates your acceptance of JSTOR's Terms and Conditions of Use, available at http://www.jstor.org/page/info/about/policies/terms.jsp. JSTOR's Terms and Conditions of Use provides, in part, that unless you have obtained prior permission, you may not download an entire issue of a journal or multiple copies of articles, and you may use content in the JSTOR archive only for your personal, non-commercial use. Please contact the publisher regarding any further use of this work. Publisher contact information may be obtained at http://www.jstor.org/action/showPublisher?publisherCode=mpsa. Each copy of any part of a JSTOR transmission must contain the same copyright notice that appears on the screen or printed page of such transmission. JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact [email protected]. Midwest Political Science Association is collaborating with JSTOR to digitize, preserve and extend access to American Journal of Political Science. http://www.jstor.org Aristotle'sAnticommunism DarrellDobbs, Universityof Houston This essayexamines Aristotle's critical review of Plato's Republic,the focus of whichreview is restricted,surprisingly, to Socrates'communistic political institutions; Aristotle hardly men- tionsany of theother important themes developed in thedialogue. -
Introduction: the New Metaphysics of Time Over the Last Several Years
History and Theory, Virtual Issue 1 (August 2012) © Wesleyan University 2012 ISSN: 1468-2303 INTRODUCTION: THE NEW METAPHYSICS OF TIME ETHAN KLEINBERG Over the last several years, the editors of History and Theory have tracked a growing trend evident not only in the articles published in our pages but also in manuscripts submitted to the journal as well as articles published in other venues. In the broadest strokes, this trend can be described as a response to the perceived limitations of a discourse predicated on language, rhetoric, and the question of representation. Whether one subscribes to the idea that historians and theorists of history took a “linguistic turn” in the 1980s,1 an increasing number of articles and monographs have taken issue with the general influence of French “post- structuralism” or “postmodernism,” with constructivism, and specifically with the work of Hayden White. These works seek to address the perceived faults of an overemphasis on the issues of “language” and representation that has obscured or misdirected the goal of actually addressing the past by perpetually worrying over how we might go about that task. Combined with the growing interest in material culture, the ways of science, and the nature of the body, it is hard to doubt the return to the real. But what strikes us as most interesting about this trend is the way that some of these theorists have sought to move beyond the emphasis on language and representation not by returning to a crude variant of objectivism or empiricism but by re-examining our relationship to the past and the past’s very nature and by attempting to construct a new metaphysics of time. -
Ast#: ___Science Knowledge Study Guide Physical
Name: ______________________________ Pd: ___ Ast#: _____ Science Knowledge Study Guide Physical Science Honors Provide a short response to the following prompts. 1. Describe how scientific knowledge is affected by new evidence (if the new evidence does NOT support the current understanding). Scientific knowledge grows and changes as new evidence is uncovered. 2. What is scientific knowledge built from? (list 3 things) Continuous testing and observation Debate (argumentation) All contribute to the EMPIRICAL EVIDENCE Confirmation (repetition & replication) 3. Why is it important that we use phrases such as “the results suggest…” or “the evidence supports…” rather than using words such as “prove” or “proof”? Using words such as “prove” violate the tentative nature of science. They imply that scientific knowledge is concrete and unchanging. However, scientific knowledge must remain open to change. 4. Under what circumstances will a scientific theory become a law? Explain. A scientific theory will NEVER become a scientific law; it cannot, nor is it supposed to. A scientific theory and a scientific law are two different things with different purposes (an apple will never become an orange). 5. Why are scientific theories rarely discarded (completely abandoned), even when new evidence doesn’t fit within the current theory? Scientific theories are rarely completely discarded because they are heavily-tested and well-supported explanations. It is rare that new evidence completely invalidates a theory; rather, it is more likely that the theory can be “tweaked” or changed slightly to accommodate the new evidence. 6. What represents the BEST explanation that science can offer? Scientific theories represent the best explanations science has to offer. -
Putnam's Theory of Natural Kinds and Their Names Is Not The
PUTNAM’S THEORY OF NATURAL KINDS AND THEIR NAMES IS NOT THE SAME AS KRIPKE’S IAN HACKING Collège de France Abstract Philosophers have been referring to the “Kripke–Putnam” theory of natural- kind terms for over 30 years. Although there is one common starting point, the two philosophers began with different motivations and presuppositions, and developed in different ways. Putnam’s publications on the topic evolved over the decades, certainly clarifying and probably modifying his analysis, while Kripke published nothing after 1980. The result is two very different theories about natural kinds and their names. Both accept that the meaning of a natural- kind term is not given by a description or defining properties, but is specified by its referents. From then on, Putnam rejected even the label, causal theory of reference, preferring to say historical, or collective. He called his own approach indexical. His account of substance identity stops short a number of objections that were later raised, such as what is called the qua problem. He came to reject the thought that water is necessarily H2O, and to denounce the idea of metaphysical necessity that goes beyond physical necessity. Essences never had a role in his analysis; there is no sense in which he was an essentialist. He thought of hidden structures as the usual determinant of natural kinds, but always insisted that what counts as a natural kind is relative to interests. “Natural kind” itself is itself an importantly theoretical concept, he argued. The paper also notes that Putnam says a great deal about what natural kinds are, while Kripke did not.