bioRxiv preprint doi: https://doi.org/10.1101/526285; this version posted January 22, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Comprehensive identification of survival-associated genes for cancers Hongde Liu1*, Kun Luo2, Huamei Li1, Xiao Sun1 1State Key Laboratory of Bioelectronics, School of Biological Science & Medical Engineering, Southeast University, Nanjing 210096, China 2Department of Neurosurgery, Xinjiang Evidence-Based Medicine Research Institute, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China *The corresponding author: Hongde Liu, e-mail:
[email protected] (HDL). Authors’ e-mails: Hongde Liu:
[email protected] (HDL); Kun Luo:
[email protected] (KL); Huamei Li:
[email protected](HML); Xiao Sun:
[email protected](XS). Highlights: ● The number of possible prognostic and diagnostic genes for cancers; ● A list of independent prognostic genes for each cancer; ● The universal prognostic genes mainly function in the spindle assembly checkpoint; ● Statistical links between mutated pathways and prognostic genes. 1 bioRxiv preprint doi: https://doi.org/10.1101/526285; this version posted January 22, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Abstract: Prognostic signature is important in estimating cancer risk, subtyping cancer, and planning treatment.