Autologous Gluteal Lipograft

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Aesth Plast Surg (2011) 35:216–224 DOI 10.1007/s00266-010-9590-y

ORIGINAL ARTICLE

Autologous Gluteal Lipograft

Beatriz Nicareta Luiz Haroldo Pereira


  • Aris Sterodimas Yves Gerard Illouz
  • ´

Received: 14 January 2010 / Accepted: 15 July 2010 / Published online: 25 September 2010 Ó Springer Science+Business Media, LLC and International Society of Aesthetic Plastic Surgery 2010

Abstract In the past 25 years, several different techniques of lipoinjection have been developed. The authors performed a prospective study to evaluate the patient satisfaction and the rate of complications after an autologous gluteal lipograft among 351 patients during January 2002 and January 2008. All the patients included in the study requested gluteal augmentation and were candidates for the procedure. Overall satisfaction with body appearance after gluteal fat augmentation was rated on a scale of 1 (poor), 2 (fair), 3 (good), 4 (very good), and 5 (excellent). The evaluation was made at follow-up times of 12 and 24 months. The total amount of clean adipose tissue transplanted to the buttocks varied from 100 to 900 ml. In nine cases, liponecrosis was treated by aspiration with a large-bore needle connected to a 20-ml syringe, performed as an outpatient procedure. Infection of the grafted area also occurred for four patients and was treated by incision drainage and use of antibiotics. Of the 21 patients who expressed the desire of further gluteal augmentation, 16 had one more session of gluteal fat grafting. The remaining five patients did not have enough donor area and instead received gluteal silicone implants. At 12 months, 70% reported that their appearance after gluteal fat augmentation was ‘‘very good’’ to ‘‘excellent,’’ and 23% responded that their appearance was ‘‘good.’’ Only 7% of the patients thought their appearance was less than good. At 24 months, 66% reported that their appearance after gluteal fat augmentation was ‘‘very good’’ (36%) to ‘‘excellent’’ (30%), and 27% responded that their appearance was ‘‘good.’’ However, 7% of the patients continued to think that their appearance was less than good. At this writing, the average follow-up time for this group of patients has been 4.9 years. The key to successful gluteal fat grafting is familiarity with the technique, knowledge of the gluteal topography, and understanding of the patient’s goals. With experience, the surgeon can predict the amount of volume needing to be grafted to produce the desired result. Although the aim of every surgeon is to produce the desired augmentation of the gluteal region by autologous fat grafting in one stage, the patient should be advised that a secondary procedure may be needed to accomplish the desired result.

Presented in the 2nd Professor Illouz Association Meeting during the 11th European Societies of Plastic Reconstructive and Aesthetic Surgery Congress in Rhodes, Greece. Winner of the 1st Illouz Prize and awarded the amount of 5000 US$.

Keywords Autologous fat transplantation Á Gluteal augmentation Á Lipograft Á Liposuction

B. Nicareta Department of Plastic Surgery, Policlinca Geral, 38 Av Nilo Pec¸anha, Rio de Janeiro 22020-100, Brazil

Fat injection reportedly started in 1893 when German physician Franz Neuber used a small piece of upper arm fat to build up the face of a patient whose cheek had a large pit caused by a tubercular inflammation of the bone [1]. In 1926, Dr. Conrad Miller warned that ‘‘the end-results in free fat transplantation depend, aside from various local and general factors, on the method and technique’’ [2].

L. H. Pereira (&) Á A. Sterodimas Department of Plastic Surgery, LH Clinic, Rua Xavier da Silveira 45/206, Rio de Janeiro 22061-010, Brazil e-mail: [email protected]

Y. G. Illouz Department of Plastic Surgery, Saint Louis Hospital, Avenue Claude-Vellefaux, 75010 Paris, France

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With the advent of liposuction in the 1980s, it became possible to aspirate and reinject fat, allowing transplantation of small volumes for soft tissue augmentation to correct contour irregularities [3]. Initially, it was performed by using microcannulas and small 5- and 10-ml syringes.
In the past 25 years, several different techniques of lipoinjection have been developed to correct various problems such as those involving the buttocks (augmentation and reshaping), trochanteric depressions, breast augmentation, scar depressions, thighs and legs (calf and ankle augmentation), small wrinkles and depressions of the face (Romberg’s disease), the nasolabial fold, the upper outer breast quadrant, and liposuction sequelae [4–8].
In 1989, the senior author (LHP) started introducing autologous fat to different anatomic areas such as the buttocks, the trochanteric regions, and the inner aspect of the thighs [9]. The authors performed a prospective study to evaluate patient satisfaction and the rate of complications after autologous gluteal lipografting.

Fig. 1 Marking of the areas to be liposuctioned and lipoinjected

intravenous sedation. The patient is placed in the prone position. Intraoperative intravenous (IV) cefazolin is administered.
3. After injection of the normal saline wetting solution containing 1:500,000 of adrenaline by a small-bore cannula and a wait of 15 min, a 60-ml syringe attached to a 4-mm blunt cannula is inserted through small incisions in the intergluteal fold as well as two incisions in the iliac crest and two additional incisions in the gluteal fold. Each incision is less than 1 cm long.

Patients and Methods

A total of 351 consecutive women underwent surgery from January 2002 to January 2008. The women ranged in age from 19 to 72 years (mean, 31.3 years). The preoperative body mass index (BMI) of the patients ranged from 17.1 to 25.6 kg/m2 (mean, 21.6 kg/m2), obtained at the first office visit. Of the 351 patients, 73 were smokers, who were asked to refrain from smoking for 1 month before and after the surgical procedure. All the patients included in the study requested gluteal augmentation and were candidates for the procedure. No other surgical procedures were performed.
4. Fat is aspirated using the syringe method. The donor sites include flanks, thighs, and knee fat. Each individual area to be aspirated is treated separately (Fig. 2a).
5. The fatty tissue aspirated is treated in the following manner. With the syringe held vertically, open end down, the fat and fluid are separated. Isotonic saline is added to the syringe. The fat and saline are separated and the exudate discarded. The procedure is repeated until the fat becomes yellow in color and free of blood and other contaminants (Fig. 2b).
The overall satisfaction with body appearance after gluteal fat augmentation was rated on a scale of 1 (poor), 2 (fair), 3 (good), 4 (very good), and 5 (excellent). The patient satisfaction scale has been used already in published papers and peer reviewed [10–12]. All the patients underwent surgery by the same team of surgeons comprising Luiz Haroldo Pereira, Aris Sterodimas, and Beatriz Nicaretta. The evaluation was made at follow-up office consultations at 12 and 24 months.
6. At completion of the liposuction procedure, access to the buttock region is gained through the same incisions in the intergluteal fold.
7. Initially, a deep plane to the gluteal muscles is created by the 4-mm cannula. Then other planes are created using the same cannula in different trajectories, always from the deeper aspect to the gluteal surface. The fat is inserted into these tunnels, beginning at the deep layer and working up into the intermediate fat compartments. The fat is injected as the cannula is withdrawn. Care should be taken to avoid injection of more fat in the superficial fat compartment. Separate incisions, if necessary, can be used to treat the whole gluteal region (Fig. 3).
Surgical Technique of Fat Grafting 1. Marking of the areas to be liposuctioned and fat grafted are made while the patient is in the standing position (Fig. 1). The areas to be lipoaspirated are parallel-line marked, and the areas to be fat grafted are only hollow marked.
2. Preoperative sedation is administered in the surgical suite. Anesthesia consists of an epidural block and

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Fig. 2 a Liposuction using the syringe technique. b The ‘‘treated’’ fat ready to be inserted using 60-ml syringes

Fig. 3 a–d Insertion of

lipograft in the gluteal area

8. Immediate postoperative dressing is performed in the area that was lipoaspirated, avoiding any pressure in the gluteal area. position when lying down, even when large amounts of fat are injected. Return to mild physical activities is allowed after the third postoperative week, and lying down supine is permitted after 2 weeks. A nonzippered pull-over female body vest is placed on the second postoperative day and kept in place for 1 month.
9. The patient remains hospitalized for 24 h. Analgesics and antiinflammatory medications are prescribed during the following 7 postoperative days. The patient is instructed to remain in the supine body

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Results

their appearance was less than good (‘‘fair’’ 6% and ‘‘poor’’ 1%) (Fig. 5).
In this study, the total amount of clean adipose tissue transplanted to the buttocks varied from 100 to 900 ml (mean, 692 ml) (Fig. 4). Nine cases of liponecrosis small in volume (2.5%) developed in the grafted gluteal area. Liponecrotic lumps were palpated at postoperative evaluation and after ultrasound confirmation. Aspiration with a large-bore needle connected to a 20-ml syringe was performed as an outpatient procedure.
At 24 months, 66% of the patients reported that their appearance after gluteal fat augmentation was ‘‘very good’’ (36%) to ‘‘excellent’’ (30%), and 27% responded that their appearance was ‘‘good,’’ whereas 7% continued to think that their appearance was less than good (‘‘fair’’ 6% and ‘‘poor’’ 1%) (Fig. 6). At this writing, the average follow-up time for this group of patients has been 4.9 years.

A correlation seemed to exist between the amount of lipograft injected and the liponecrosis complication rate. The total gluteal fat injected was 401 to 600 ml for six patients, 601 to 800 ml for two patients, and 801 to 900 ml for one patient. Infection of the grafted area also occurred for four patients (1%), which was treated by incision drainage and use of oral cephalexin for 7 days. Prompt recognition of the infection signs led to immediate treatment that did not alter the final aesthetic result. However, one case needed further fat grafting of 20 ml, which was performed as an outpatient procedure.
Patient 1 A 24-year-old woman presented reporting that she had ‘‘not enough buttocks,’’ which made her ‘‘unattractive’’ (Fig. 7a, c). Liposuction of the back, flanks, and abdomen together with autologous gluteal lipografting was performed. The total gluteal fat transfer was 530 ml. Photos were taken 3 years after the procedure (Fig. 7b, d). The woman’s

There were no cases of cellulitis in donor and grafted areas, no deep vein thrombosis, and no pulmonary embolism. The postoperative body mass index (BMI) of the patients ranged from 17.4 to 25.2 kg/m2 (mean of 21.5 kg/ m2), obtained at the 24-month office visit. Of the 21 patients (6%) who expressed the desire for further gluteal augmentation, 16 had one more session of gluteal fat grafting. No complications were reported for the patients who underwent an additional fat-grafting session. The remaining five patients did not have enough donor area and instead received gluteal silicone implants.
At 12 months, 70% of the patients reported that their appearance after gluteal fat augmentation was ‘‘very good’’ (38%) to ‘‘excellent’’ (32%), and 23% responded that their appearance was ‘‘good.’’ Only 7% of the patients thought

Fig. 5 Schematic representation of the degree of satisfaction 12 months after autologous gluteal lipografting

Fig. 4 Diagram of the total amount of clean adipose tissue transplanted to the buttocks for the 351 patients
Fig. 6 Schematic representation of the degree of satisfaction 24 months after autologous gluteal lipografting

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Fig. 7 a,c Preoperative view of 24-year-old woman complaining of unattractive ‘‘buttocks.’’ b,d Postoperative view of 24-year-old woman 3 years after a 530-ml autologous gluteal lipograft. Her satisfaction 12 and 24 months postoperatively was rated as excellent

  • Patient 3
  • satisfaction 12 and 24 months postoperatively was rated as

excellent.
A 39-year-old woman complained about her buttocks (Fig. 10a, c). Liposuction of the back, flanks, and abdomen together with autologous gluteal lipografting was performed. The total gluteal fat transfer was 390 ml. Photos were taken 4 years after the procedure (Fig. 10b, d). The woman’s satisfaction 12 and 24 months postoperatively was rated as good.
Patient 2 A 30-year-old woman presented for liposuction and moderate buttock enhancement (Fig. 8a, c). Liposuction of the back, flanks, and abdomen as part of the composite body contouring procedure was done. Autologous gluteal lipografting was performed. The total gluteal fat transfer was 460 ml. Photos were taken 4 years after the procedure (Fig. 8b, d). The woman’s satisfaction 12 and 24 months postoperatively was rated as very good. Computer tomography (CT) imaging of the gluteal area preoperatively and 24 months postoperatively is shown in Fig. 9. Arrows are incorporated in the postoperative CT scan showing the transplanted fat.

Discussion

As in every surgical procedure, the success of gluteal fat grafting is dependent on many factors: the techniques and instruments used to harvest the fat tissue, the fat processing, the volumes of fat implantation, the sites to be

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Fig. 8 a,c Preoperative view of 30-year-old woman requesting ‘‘buttock’’ enhancement. b,d Postoperative view of 30-yearold woman 4 years after a 460- ml autologous gluteal lipograft. Her satisfaction 12 and 24 months postoperatively was rated as very good

Fig. 9 a Preoperative computer tomography (CT) imaging of a 30-year-old woman’s glutealarea. b Postoperative CT imaging of 30-year-old woman 24 months after an autologous gluteal lipograft. Arrows indicate the fat graft

implanted, the levels of placement, and even the individual patient. Because of this variability and perhaps other factors not yet understood, the results of fat grafting with some techniques, in some patients, and in some areas can be unpredictable. A standard procedure has not been adopted by all practitioners. No agreement exists as to the best way of processing the fat to ensure maximal take and viability of the graft [13].
However, certain proven points should be taken into account when gluteal augmentation is performed. No statistical differences in adipocyte viability have been demonstrated among abdominal fat, thigh fat, flank fat, and

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Fig. 10 a,c Preoperative view of 39-year-old woman complaining about her buttocks. b,d Postoperative view of 39- year-old woman 4 years after an autologous gluteal lipograft. The total gluteal fat transfer was 390 ml. Her satisfaction 12 and 24 months postoperatively was rated as good

knee fat donor sites [14, 15]. A recent paper has reported a significant difference in adipose cell concentrations obtained at the different harvest sites. In the lower abdomen, the adipose cell concentration was greater than in other areas, but no significant difference was found in relation to the inner thigh [16]. A mixture of fat obtained from the abdomen, thigh, flank, and knee areas was used for the majority of the patients in this study because the amount of required fat graft could not be obtained by choosing only a single harvest area. tissue architecture of fat will result in eventual necrosis of the injected fat.
Guerrerosantos [17] has performed numerous successful autologous fat transfers and advocates injection into the muscle as well as deep into the fat. The transplanted fat must have access to a blood supply [18]. The creation of multiple tunnels ensures an adequate blood supply for the grafted fat.
Grafting of the superficial gluteal fat compartment must not exceed 20 ml per tunnel due to low vascularity and excessive compression of the area that can result in liponecrosis [9]. Intramuscular fat grafting should be done in tunnels also, and retrograde injection should be performed, to avoid intravascular fat injection. Pressure should not be applied in the grafted gluteal area [19]. Excess fat should not be injected at one spot.
Recent reports have shown that mechanical centrifugation does not appear to enhance immediate fat tissue viability before implantation [15]. An important consideration for harvesting and refinement in preparation for grafting is to respect and maintain the tissue architecture of living fat. Any mechanical or chemical insult that damages the fragile

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For predictable results, the surgeon should refine the fat into relatively pure living tissue using sterile conditions and avoiding external contact, thus preventing contamination. Transplanting a high percentage of nonviable components such as blood and local factors reduces the potential for accurate volume estimation. the surgeon can predict the amount of volume needing to be grafted to produce the desired result [9, 28, 29]. Regenerative cell-based strategies such as those encompassing the use of stem cells hold tremendous promise for augmentation of the soft tissue space. Preclinical studies and early clinical series show that adipose-derived stem cells offer the possibility of finally fulfilling the key principle of replacing like with like as an aesthetic filler without the drawbacks of current technology [30].
In contrast to the facial region, in which graft absorption is notoriously high, the rate of volume loss in the gluteal area and lower limbs is known to be much lower [9]. The average tissue loss because of reabsorption after lipoinjection in the buttock varies between 24% and 36%, and stabilization after the procedure can take up to 1 year [5, 20]. That is the reason why the evaluation was made at a minimal follow-up time of 12 months and repeated at 24 months postoperatively. No significant difference in patient satisfaction was found when the 12- and 24-month results were compared (Figs. 5 and 6).
In cell-assisted lipotransfer (CAL), autologous adiposederived stem cells (ADSCs) are used in combination with lipoinjection. A stromal vascular fraction (SVF) containing ADSCs is freshly isolated from half of the aspirated fat and recombined with the other half. This process converts relatively ADSC-poor aspirated fat to ADSC-rich fat. The preliminary results suggest that CAL is effective and safe for soft tissue augmentation [31, 32].
There seems to be a relative correlation of the injected volume and patient satisfaction. The patients who rated their result as excellent at 24 months had 270 to 740 ml (mean, 575 ml) injected in their gluteal area. On the other hand, the patients who rated their result as poor or less than poor at 24 months had 130 to 290 ml (mean, 190 ml) injected in their gluteal area. There was no correlation between the cases in which complications occurred and low patient satisfaction. All the patients who had complications from the procedure rated their satisfaction as 3 (good) or 4 (very good) (mean, 3.4). The patients who rated their satisfaction as 2 (less than good) or 1 (poor) were those who did not achieve their desired gluteal augmentation. Comparison of the mean pre- and postoperative BMIs showed that the autologous gluteal lipograft is a method of repositioning the fat from the waist and hips to the buttocks. Pre- and postoperative CT scans were performed for the patients who decided to undergo this procedure and cover the extra cost for it. Of 351 patients, only 65 agreed to do so, and that is why this parameter was not included in the evaluation.
Another study has confirmed that the CAL fat can survive better (35% better on the average) than non-CAL fat and that the microvasculature can be detected more prominently in CAL fat, especially in the outer layers of the fat transfer [33].Well-designed studies with long-term results are needed to compare autologous fat transplantation and the stem-cell-enriched fat tissue [34].

Conclusion

The key to successful fat grafting is familiarity with the technique, knowledge of the gluteal topography, and understanding of the patient’s goals. Although the aim of every surgeon is to produce the desired augmentation of the gluteal region by autologous fat grafting in one stage, the patient should be advised that a secondary procedure may be needed to accomplish the desired result.

Conflict of interest The authors declare that they have no conflict of interest of disclose.

Surgeons have come to realize that transplanted fat can create not only satisfying changes in contour but also longlasting results [21]. In 2000, a 7-year experience of grafting aspirated fat in the gluteal region for 233 patients was presented. In 90% of the cases, the results were considered satisfactory [22]. A recent report has shown long-lasting results of gluteal fat grafting [23].

References

1. Neuber F (1893) Fettransplantation. Chir Kongr Verhandl Dtsch
Ges Chir 22:66
2. Miller JJ, Popp JC (2002) Fat hypertrophy after autologous fat transfer. Ophthal Plast Reconstr Surg 18:228–231
3. Illouz YG (1986) The fat cell ‘‘graft’’: a new technique to fill depressions. Plast Reconstr Surg 78:122–123
4. Matsudo PK, Toledo LS (1988) Experience of injected fat grafting. Aesthetic Plast Surg 12:35–38
5. Illouz YG, Sterodimas A (2009) Autologous fat transplantation to the breast: a personal technique with 25 years of experience. Aesthetic Plast Surg. Epub ahead of print 4 June

The current study confirms the senior author’s clinical observation over more than 18 years, with autologous gluteal lipograft producing high patient satisfaction and a low rate of complications.
The limitations of fat transplantation are well known, particularly the long-term unpredictability of volume maintenance [24–26]. The amount of donor fat available also is an important limiting factor [27]. With experience,

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  • Krok 2. Medicine

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    Sample test questions Krok 2 Medicine () Терапевтичний профiль 2 1. A 25-year-old woman has been A. Transfer into the inpatient narcology suffering from diabetes mellitus since she department was 9. She was admitted into the nephrology B. Continue the treatment in the therapeutic unit with significant edemas of the face, arms, department and legs. Blood pressure - 200/110 mm Hg, C. Transfer into the neuroresuscitation Hb- 90 g/L, blood creatinine - 850 mcmol/L, department urine proteins - 1.0 g/L, leukocytes - 10-15 in D. Compulsory medical treatment for the vision field. Glomerular filtration rate - alcoholism 10 mL/min. What tactics should the doctor E. Discharge from the hospital choose? 5. After eating shrimps, a 25-year-old man A. Transfer into the hemodialysis unit suddenly developed skin itching, some areas B. Active conservative therapy for diabetic of his skin became hyperemic or erupted into nephropathy vesicles. Make the diagnosis: C. Dietotherapy D. Transfer into the endocrinology clinic A. Acute urticaria E. Renal transplantation B. Hemorrhagic vasculitis (Henoch-Schonlein purpura) 2. A 59-year-old woman was brought into the C. Urticaria pigmentosa rheumatology unit. Extremely severe case D. Psoriasis of scleroderma is suspected. Objectively she E. Scabies presents with malnourishment, ”mask-like” face, and acro-osteolysis. Blood: erythrocytes 6. A 25-year-old woman complains of fatigue, - 2.2 · 109/L, erythrocyte sedimentation rate - dizziness, hemorrhagic rashes on the skin. 40 mm/hour. Urine: elevated levels of free She has been presenting with these signs for a · 12 oxyproline. Name one of the most likely month.
  • COSMETIC All of These Features Come 6–9 Supplemental Digital Content Is Available for This Article

    COSMETIC All of These Features Come 6–9 Supplemental Digital Content Is Available for This Article

    COSMETIC Aging of the Upper Lip: Part II. Evidence-Based Rejuvenation of the Upper Lip—A Review of 500 Consecutive Cases Patrick L. Tonnard, M.D., Background: Findings from photometric analysis of soft tissue on cranial mag- Ph.D. netic resonance imaging demonstrate that the aging upper lip shows signifi- Alexis M. Verpaele, M.D., 05/22/2019 on lnf+zCl8aG1GefrmFSsnrHDYWSHCKCLzozQMxl0MmI4A3EdDDFYR+Ytn4nfEjybn/aY5U+kZk19usAIkotkrAg== by http://journals.lww.com/plasreconsurg from Downloaded cant lengthening, thinning, volume loss, and deepening of the nasolabial folds. Ph.D. In this study, these findings are implemented in a review of 500 cases of upper Lisa E. Ramaut, M.D. Downloaded lip rejuvenation to propose an evidence-based strategy for surgical rejuvena- Phillip N. Blondeel, M.D., tion of the upper lip. Ph.D from Methods: The charts of 500 consecutive surgical perioral rejuvenation patients http://journals.lww.com/plasreconsurg Ghent, Belgium treated by the senior authors (P.L.T. and A.M.V.) from 2014 until 2018 were reviewed. The surgical methods of lip lift and fat grafting were described in relation to the cases and the metric data. Results: Of the 500 patients, 51 had an isolated procedure such as a lip lift (3 percent), lip augmentation (3 percent), augmen- tation of the nasolabial folds (2 percent), or skin resurfacing by lnf+zCl8aG1GefrmFSsnrHDYWSHCKCLzozQMxl0MmI4A3EdDDFYR+Ytn4nfEjybn/aY5U+kZk19usAIkotkrAg== (2 percent). The remaining 449 patients underwent combinations of lip lift, augmentation of the lip and nasolabial fold (32 percent), lip lift with augmentation of the lip and nasolabial fold with resurfacing (30 percent), lip augmentation and resurfacing (14 percent), or lip lift and resurfacing (14 percent).
  • The Abstracts Which Follow Have Been Classifled for the Convenience of The

    The Abstracts Which Follow Have Been Classifled for the Convenience of The

    The abstracts which follow have been classifled for the convenience of the reader under the following headings : Experimental Studies, Animal Tumors The Digestive Tract Nature of Cancer, Etiologic Theories The Liver General Clinical Observations, Blood The Pancreas Studies Retroperitoneal Tumors, Cysts and Tu- Diagnosis and Treatment mors of the Mesentery Tumors of the Skin and Muscles The Spleen The Oral Cavity, Nose and Paranasal The Female Genital Tract Sinuses, Throat, Salivary Glands, The Genito-Urinary System Carotid Body The Adrenal Glands The Eye The Nervous System The Ear The Bones and Joints The Thyroid Gland The Lymphatic System The Breast Statistics Intrathoracic Tumors Education As with any such scheme of classification, overlapping has been unavoidable. Shall an article on " Cutaneous Melanoma, an Histological Study " be grouped with the articles on Histology or with the Skin Tumors? Shall Traumatic Cerebral Tu- mors go under Trauma or The Nervous System? The reader's choice is likely to depend upon his personal interests; an editor may be governed by no such considera- tions. The attempt has been made, therefore, to put such articles in the group where they would seem most likely to be sought by the greatest number. It is hoped that this aim has not been entirely missed. As abstractors are never perfect, and as the opinions expressed may on occasion seem to an author not to represent adequately his position, opportunity is offered any such to submit his own views for publication. The JOURNALwill not only wel- come correspondence of this nature but hopes in the future to have a large number of author abstracts, so that the writer of a paper may present his subject in his own way.
  • Diseases and Disorders of the Gastrointestinal Tract

    Diseases and Disorders of the Gastrointestinal Tract

    CHAPTER 1 Esophagus. is unknown, and healing generally occurs DISEASES AND DISORDERS OF THE Stomach. spontaneously within 10 days to two weeks. Small intestine. Aphthous stomatitis is most common in young GASTROINTESTINAL TRACT (10 CONTACT HOURS) Large intestine. girls and female teenagers. Its cause is unknown, Rectum. but stress, fatigue, anxiety and fever predispose Learning objectives: Anal canal. its development. Treatment is geared to symptom ! Review the anatomy of the gastrointestinal relief through the use of a topical anesthetic and The accessory glands and organs consist of the system. reduction of predisposing factors.5 salivary glands, liver, gallbladder and bile ducts ! Describe diseases of the oral cavity. and the pancreas.9 The major functions of the GI Miscellaneous infections ! Identify treatment of diseases of the oral system are digestion and elimination of waste Candidiasis (thrush): Fungal infection cavity. products from the body.5,9 that causes cream or bluish-white patches ! Explain the types of disorders and diseases of exudates to appear on the tongue, mouth, affecting the esophagus. Diseases and disorders of the GI system can and/or pharynx. Persons at high risk include ! Evaluate treatment initiatives for disorders range from mild annoyances to life-threatening premature neonates, older adults, those and diseases affecting the esophagus. conditions. It is important that the nurse with suppressed immune systems, persons ! Identify pathophysiology of gastric diseases recognize the numerous abnormalities that can taking antibiotics, or persons taking steroids and disorders. occur, and how to most effectively intervene to for a long period of time. For infants, the ! Evaluate treatment initiatives for gastric help the patient return to a state of maximum oral mucosa is swabbed with nystatin after diseases and disorders.
  • Plastic Surgery and Modern Techniques Logas C, Et Al

    Plastic Surgery and Modern Techniques Logas C, Et Al

    Plastic Surgery and Modern Techniques Logas C, et al. Plastic Surgery Mod Tech: PSMT-142. Review Article DOI: 10.29011/2577-1701.100042 Biostimulatory Injectables for the Treatment of Cellulite and Gluteal Enhancement Christopher Logas1*, Corey Kosche2, Maritza Perez MD3, Gabriel J. Martinez-Diaz MD4 1Fourth Year Medical Student at Midwestern University, Downers Grove, IL, USA 2Third Year Medical Student at Rush University School of Medicine, IL, USA 3Clinical Professor at Mount Sinai St. Luke’s and Mount Sinai West, New York, USA 4MD, Aesthetics and Dermatology, Chicago, IL, USA *Corresponding author: Christopher Logas, Fourth Year Medical Student at Midwestern University, Downers Grove, IL, USA. Tel: +13522081481; Email: [email protected] Citation: Logas C, Kosche C, Perez M, Martinez-Diaz J (2018) Biostimulatory Injectables for the Treatment of Cellulite and Glu- teal Enhancement. Plastic Surgery Mod Tech: PSMT-142. DOI: 10.29011/2577-1701.100042 Received Date: 04 September, 2018; Accepted Date: 28 September, 2018; Published Date: 08 October, 2018 Abstract The biostimulatory injectable fillers poly-l-lactic acid and calcium hydroxylapatite have numerous indications and are increasingly used by dermatologists for novel applications. Initially approved for the treatment of HIV-associated lipoatrophy, their stimulation of collagen synthesis leads to a filling effect with long-lasting results. As such, they can be used for numerous cosmetic purposes including wrinkles, scars, and body contouring. In this review, we discuss the biological properties and indications for these two fillers, as well as our experience and technique in using them to treat cellulite and in gluteal enhancement Introduction procedure that has shown promising results in our patients.
  • Krok 2 Medicine

    Krok 2 Medicine

    Sample test questions Krok 2 Medicine () Терапевтичний профiль 2 1. A patient with Morgagni-Adams-Stokes resonance and absence of respiration.What is syndrome has fainted when walking up the the most likely diagnosis in this case? stairs. The skin is pale, the pupils are dilated, tonoclonic spasms are observed, rib cage is A. Spontaneous pneumothorax immobile. Make the diagnosis: B. Hemothorax C. Lobar pneumonia A. Clinical death D. Pulmonary embolism B. Social death E. Acute pleurisy C. Preagony D. Agony 6. A 34-year-old man on the 3rd day E. Biological death of ceftriaxone treatment for acute otitis (daily dosage - 2 grams) developed diarrhea 2. A 32-year-old welder complains of weakness occurring 5-6 times per day. Feces are without and fever. His illness initially presented as mucus or blood admixtures. Temperature is tonsillitis one month earlier. On examination: 36.6oC. Gregersen reaction (occult blood in o temperature - 38.9 C, respirations - 24/min., feces) is negative. Stool culture detected no pulse - 100/min., blood pressure - 100/70 mm pathogenic germs. What is the most likely Hg, hemorrhages on the legs, enlargement of cause of diarrhea in this case? the lymph nodes. Complete blood count shows Hb- 70 g/L, RBC- 2.2·1012/L, WBC- 3.0·109/L A. Antibiotic-associated diarrhea with 32% of blasts, 1% of eosinophiles, 3% of B. Intestinal dysbiosis bands, 36% of segments, 20% of lymphocytes, C. Bacterial overgrowth syndrome and 8% of monocytes, ESR- 47 mm/hour. D. Ulcerative colitis What is the cause of anemia in this case? E.