Autism: Symptoms, Causes, and Treatments
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Press Release 23/5/2018
THE KARLOVY VARY FESTIVAL TO HONOR ACADEMY AWARD-WINNING DIRECTOR BARRY LEVINSON At this year’s Karlovy Vary festival, screenwriter-producer-director Barry Levinson, who won an Academy Award for Rain Man, will accept the Crystal Globe for Outstanding Artistic Contribution to World Cinema. The Karlovy Vary festival continues its tradition of recognizing the most important personalities of world cinema, the likes of which include directors William Friedkin, Jerry Schatzberg, and Ken Loach, and screenwriter Paul Laverty. In his writing and directing capacity, Academy Award winner and five-time nominee Barry Levinson deftly combines personal stories with an often satirical look at society, and his movies have fundamentally influenced numerous young filmmakers. Barry Levinson established himself as a writer of successful television shows. With his onetime wife, Valerie Curtin, he then wrote the movie script for Norman Jewison’s courtroom drama …and justice for all (1979), which brought them an Oscar nomination. He debuted as a director with the comedy-drama Diner (1982), receiving his second Oscar nomination for the script. Ivan Král, a Czech musician based in the US, co- wrote the film music. Subsequent titles confirmed his reputation with critics and audiences: The Natural (1984) with Robert Redford, Tin Men (1987) with Richard Dreyfuss and Danny DeVito, and Good Morning, Vietnam (1987) with Robin Williams. This year marks the 30th anniversary of the legendary picture Rain Man (1988), awarded four Oscars (e.g. Best Director for Barry Levinson) and numerous other honors, including the Golden Bear at the Berlinale and the David di Donatello for Best Foreign Film. -
Overview of Biomedical Treatments Presentation
Folic Acid Decreases Risk of Autism 38%, if used early Schmidt et al 2013 – CHARGE study of 429 ASD families, 278 typical families Lower folic acid intake during first month of pregnancy in ASD moms (655 mcg vs 779); intake above 600 mcg associated with 38% decreased risk of ASD in children, and higher intake decreased risk more. Most important for mothers with MTHFR 677 C>T variant genotypes. Folic Acid decreases risk of ASD if taken near conception (cont.) Suren et al 2013 – study of 85,176 Norwegian children, including 270 with ASD. In children whose mothers took folic acid (400 mcg) between 4 weeks prior to conception to 8 weeks after conception, 0.10% (64/61 042) had autistic disorder, compared with 0.21% (50/24 134) in those unexposed to folic acid. 39% lower risk of ASD in those who took prenatal folic acid (400 mcg); Little benefit if taken after 8 weeks Overview of Dietary, Nutritional, and Medical Treatments for Autism James B. Adams, Ph.D. President’s Professor, Arizona State University President, Autism Society of Greater Phoenix President, Autism Nutrition Research Center Chair of Scientific Advisory Board, Neurological Health Foundation Father of a daughter with autism http://autism.asu.edu Our research group is dedicated to finding the causes of autism, how to prevent autism, and how to best help people with autism. Nutrition: vitamins, minerals, fatty acids, amino acids Metabolism: glutathione, methylation, sulfation, oxidative stress Mitochondria – ATP, muscle strength, carnitine Toxic Metals and Chelation Gastrointestinal -
Measuring the Effectiveness of Play As an Intervention to Support
Measuring the Effectiveness of Play as an Intervention to Support Language Development in Young Children with Autism Spectrum Disorder: A Hierarchically- Modeled Meta-Analysis by Gregory V. Boerio Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Education in the Educational Leadership Program Youngstown State University May, 2021 Measuring the Effectiveness of Play as an Intervention to Support Language Development in Young Children with Autism Spectrum Disorder: A Hierarchically- Modeled Meta-Analysis Gregory V. Boerio I hereby release this dissertation to the public. I understand that this dissertation will be made available from the OhioLINK ETD Center and the Maag Library Circulation Desk for public access. I also authorize the University or other individuals to make copies of this thesis as needed for scholarly research. Signature: _______________________________________________________________ Gregory V. Boerio, Student Date Approvals: _______________________________________________________________ Dr. Karen H. Larwin, Dissertation Chair Date _______________________________________________________________ Dr. Patrick T. Spearman, Committee Member Date _______________________________________________________________ Dr. Carrie R. Jackson, Committee Member Date _______________________________________________________________ Dr. Matthew J. Erickson, Committee Member Date _______________________________________________________________ Dr. Salvatore A. Sanders, Dean of Graduate Studies Date ii © G. Boerio 2021 iii Abstract The purpose of the current investigation is to analyze extant research examining the impact of play therapy on the development of language skills in young children with autism spectrum disorder (ASD). As rates of ASD diagnoses continue to increase, families and educators are faced with making critical decisions regarding the selection and implementation of evidence-based practices or therapies, including play-based interventions, to support the developing child as early as 18 months of age. -
A Study of Musical Affect in Howard Shore's Soundtrack to Lord of the Rings
PROJECTING TOLKIEN'S MUSICAL WORLDS: A STUDY OF MUSICAL AFFECT IN HOWARD SHORE'S SOUNDTRACK TO LORD OF THE RINGS Matthew David Young A Thesis Submitted to the Graduate College of Bowling Green State University in partial fulfillment of the requirements for the degree of MASTER OF MUSIC IN MUSIC THEORY May 2007 Committee: Per F. Broman, Advisor Nora A. Engebretsen © 2007 Matthew David Young All Rights Reserved iii ABSTRACT Per F. Broman, Advisor In their book Ten Little Title Tunes: Towards a Musicology of the Mass Media, Philip Tagg and Bob Clarida build on Tagg’s previous efforts to define the musical affect of popular music. By breaking down a musical example into minimal units of musical meaning (called musemes), and comparing those units to other musical examples possessing sociomusical connotations, Tagg demonstrated a transfer of musical affect from the music possessing sociomusical connotations to the object of analysis. While Tagg’s studies have focused mostly on television music, this document expands his techniques in an attempt to analyze the musical affect of Howard Shore’s score to Peter Jackson’s film adaptation of The Lord of the Rings Trilogy. This thesis studies the ability of Shore’s film score not only to accompany the events occurring on-screen, but also to provide the audience with cultural and emotional information pertinent to character and story development. After a brief discussion of J.R.R. Tolkien’s description of the cultures, poetry, and music traits of the inhabitants found in Middle-earth, this document dissects the thematic material of Shore’s film score. -
Environmental and Genetic Factors in Autism Spectrum Disorders: Special Emphasis on Data from Arabian Studies
International Journal of Environmental Research and Public Health Review Environmental and Genetic Factors in Autism Spectrum Disorders: Special Emphasis on Data from Arabian Studies Noor B. Almandil 1,† , Deem N. Alkuroud 2,†, Sayed AbdulAzeez 2, Abdulla AlSulaiman 3, Abdelhamid Elaissari 4 and J. Francis Borgio 2,* 1 Department of Clinical Pharmacy Research, Institute for Research and Medical Consultation (IRMC), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia; [email protected] 2 Department of Genetic Research, Institute for Research and Medical Consultation (IRMC), Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia; [email protected] (D.N.A.); [email protected] (S.A.) 3 Department of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia; [email protected] or [email protected] 4 Univ Lyon, University Claude Bernard Lyon-1, CNRS, LAGEP-UMR 5007, F-69622 Lyon, France; [email protected] * Correspondence: [email protected] or [email protected]; Tel.: +966-13-333-0864 † These authors contributed equally to this work. Received: 26 January 2019; Accepted: 19 February 2019; Published: 23 February 2019 Abstract: One of the most common neurodevelopmental disorders worldwide is autism spectrum disorder (ASD), which is characterized by language delay, impaired communication interactions, and repetitive patterns of behavior caused by environmental and genetic factors. This review aims to provide a comprehensive survey of recently published literature on ASD and especially novel insights into excitatory synaptic transmission. Even though numerous genes have been discovered that play roles in ASD, a good understanding of the pathophysiologic process of ASD is still lacking. -
Helping You to Focus Better
#1 BOOK ONE word search Helping you to focus better Crystalens® vision workbook “your road to visual rejuvenation” DUNKIN DONUTS F J N H I A F L R W X D D T Z K T P E K Y W X C S T V B Q L O D V H O O R F Y X S O T E O M G M Q R D I Q K L T H I Z B J Y T T Y H G M V C Y Y T F L E L L E H J J P L I Y C H U J Y W N C E R K F O A R I T C R O I S S A N T W F R P C N F Z I X Y N Y E Y J X L N Y F R P A I L N E O L S W Z T E F K D U O C X D C J B Y L K G N Q E T T A L V C R W D C K D Q N N S A G R U B W F N U W R H U X O M D D U Q C L K W P B R P B W B P T U M J D R T F W S L T E I M A Y Y P X G E J X C V V S C L K I L P D V M A V H S Y V Q Y W N N A T W O N I J D C U N R Y Z F I J Q O A K D K N E A D T M U A J F P V D R O U E L E G A B E V Y T E J K V G P S H D E B M M H T C R Q T G K U W V F Z W R U K P T R O I J U B Y U H J E L E E X W Q V Q F B N M G J A W M U F F I N Z E G X K A S N B P A S V P Q X A L K O D U D A Q Bagel Drive Thru Beans Hazelnut Cappuccino Iced Coffee Latte Croissant Muffin Doughnut Vanilla #1 CANDY BARS W G I X B R B U Q I U C V Q S V K O O I H Y V S W Q Q U O R C N D C T Y Z K F B O O WH M M Y A W C E J T V Y I R R P S W O U U R K A L N O O E R N X J B X M G G J O O G C U Q W C Z Q T D H V M O W O W R E Q O C M V F U I L Y E D O R A O W R D M E O S L G Q M C S A I K E K E E K A J U L D E S E E R M B W Z S S O N Y K R L J Q B Y T A S H U H Y Q S M U V A U A I M P A A U R B T M N K E H E B M C O B R E O R T M S T V T I L H E R S H E Y Y V K L N N B E K I K H I U T M J T T V K B B A B D R W K C A K M E F K A T Q B S A -
Autism Handout
Autism, a Pervasive Dilemma Developed by Alan Ascher New York State Biology-Chemistry Professional Development Network For the My Environment, My Health, My Choices project University of Rochester Rochester, NY Abstract: Research suggests that autism may be due to a combination of environmental factors which impact genetic information and lead to errors in the development process during gestation. Students explore autism and engage in research on the causes of autism through problem- based learning and a Web Quest. They will create an informational brochure based on their research findings. My Environment, My Health, My Choices 1 © 2006, University of Rochester May be copied for classroom use Table of Contents Pre/Post Test 3-4 Pre/Post Test Answer Key 5-6 Learning Context 7 Procedure 8 Instructions for Implementing the Problem-Based Learning Activity 9 PBL Chart 10 Problem-Based Learning Activity 11-14 WebQuest 15-16 Informational Brochure 17 New York State Learning Standards 18 Teachers, we would appreciate your feedback. Please complete our brief, online Environmental Health Science Activity Evaluation Survey after you implement these lessons in your classroom. The survey is available online at: www.surveymonkey.com/s.asp?u=502132677711 My Environment, My Health, My Choices 2 © 2006, University of Rochester May be copied for classroom use (Student Pre/Post Test) Name _________________________________ Class _____ 1. Autism is most likely caused by 1. poor parenting when a child is young 2. a specific environmental chemical 3. poor nutrition 4. the exact cause of autism in not yet known 2. Some scientists believe that autism results from changes in the “brain stem” that are caused by gene mutations in the HOXA 1 gene. -
REVIEW ARTICLE the Genetics of Autism
REVIEW ARTICLE The Genetics of Autism Rebecca Muhle, BA*; Stephanie V. Trentacoste, BA*; and Isabelle Rapin, MD‡ ABSTRACT. Autism is a complex, behaviorally de- tribution of a few well characterized X-linked disorders, fined, static disorder of the immature brain that is of male-to-male transmission in a number of families rules great concern to the practicing pediatrician because of an out X-linkage as the prevailing mode of inheritance. The astonishing 556% reported increase in pediatric preva- recurrence rate in siblings of affected children is ϳ2% to lence between 1991 and 1997, to a prevalence higher than 8%, much higher than the prevalence rate in the general that of spina bifida, cancer, or Down syndrome. This population but much lower than in single-gene diseases. jump is probably attributable to heightened awareness Twin studies reported 60% concordance for classic au- and changing diagnostic criteria rather than to new en- tism in monozygotic (MZ) twins versus 0 in dizygotic vironmental influences. Autism is not a disease but a (DZ) twins, the higher MZ concordance attesting to ge- syndrome with multiple nongenetic and genetic causes. netic inheritance as the predominant causative agent. By autism (the autistic spectrum disorders [ASDs]), we Reevaluation for a broader autistic phenotype that in- mean the wide spectrum of developmental disorders cluded communication and social disorders increased characterized by impairments in 3 behavioral domains: 1) concordance remarkably from 60% to 92% in MZ twins social interaction; 2) language, communication, and and from 0% to 10% in DZ pairs. This suggests that imaginative play; and 3) range of interests and activities. -
Evidence-Based Interventions for Autism Spectrum Disorders
Evidence-Based Interventions for Autism Spectrum Disorders Scott Lindgren, Ph.D. Alissa Doobay, Ph.D. May 2011 This research was completed for the Iowa Department of Human Services by the Center for Disabilities and Development of the University of Iowa Children’s Hospital. The views expressed are the independent products of university research and do not necessarily represent the views of the Iowa Department of Human Services or The University of Iowa. TABLE OF CONTENTS PREFACE ………………………………………………………………………………… 3 DEFINING AUTISM SPECTRUM DISORDERS (ASD) ……………………………... 4 ASSESSMENT OF AUTISM SPECTRUM DISORDERS ……………………………... 6 INTERVENTIONS FOR AUTISM SPECTRUM DISORDERS .……………………… 9 Need for Evidence-Based Interventions ……………………………………… 9 Identifying Effective Interventions …………………………………………… 9 Basic Principles of Effective Early Intervention …………………………….. 10 Research on ASD Interventions ………………………………………………. 11 Interventions Supported by Significant Scientific Evidence ……………….. 12 Applied Behavior Analysis (ABA) …………………………….……….… 12 Early Intensive Interventions ………………………………...…………... 14 Social Skills Training ……………………………………………………... 14 Cognitive-Behavioral Therapy ……………………………………...…….. 15 Medication ……………………………………………………………....... 15 Other Evidence-Based Interventions ……………………………………... 16 Interventions with Promising or Emerging Evidence ………………………. 17 Interventions with Limited Scientific Evidence ……………………………… 17 Interventions that are Not Recommended ……………………..…………….. 20 Using these Findings for Treatment Planning ……………………………….. 20 SUMMARY -
Epidemiology Report of Autism in California
Report to the Legislature on the Principal Findings from The Epidemiology of Autism in California: A Comprehensive Pilot Study IN CALIFORNIA AUTISM M.I.N.D. Institute University of California, Davis October 17, 2002 THE EPIDEMIOLOGY OF UC Davis Project Staff: ○○○○○○○○○○○○○○○○○○○○○○○○○○○○○ Robert S. Byrd, M.D., M.P.H. Principal Investigator Allyson C. Sage, R.N., M.P.H. Project Manager Janet Keyzer, R.N.C., M.P.A. Lead Chart Abstractor Rachel Shefelbine Research Assistant/ADI-R Administrator Kasie Gee, M.P.H. Research Assistant Kristen Enders Administrative Assistant Jonathan Neufeld, Ph.D. Clinical Psychologist Nhue Do Post Graduate Researcher/ADI-R Administrator Kelly Heung, M.S. Post Graduate Researcher/ADI-R Administrator IN CALIFORNIA Tiffany Hughes Post Graduate Researcher Ruth Baron, R.N. Chart Abstractor Andrea Moore, M.S.W. Chart Abstractor Bonnie Walbridge, R.N., M.P.H. Chart Abstractor/ADI-R Administrator Steven Samuels, Ph.D. Statistical Consultant Daniel Tancredi, M.S. Statistical Consultant Jingsong He, M.S. Statistician Emma Calvert Student Assistant Diana Chavez Student Assistant Anna Elsdon Student Assistant Lolly Lee Student Assistant Denise Wong Student Assistant UCLA Site Project Staff: ○○○○○○○○○○○○○○○○○○○○○○○○○○○○○○ AUTISM Marian Sigman, Ph.D. Co-Investigator Michael Bono, Ph.D. Co-Investigator Caitlin Beck Project Manager/ADI-R Administrator Sara Clavell Research Assistant/ADI-R Administrator Elizabeth Lizaola Research Assistant/ADI-R Administrator Vera Meyerkova Research Assistant/ADI-R Administrator THE EPIDEMIOLOGY -
Teaching Social Studies Through Film
Teaching Social Studies Through Film Written, Produced, and Directed by John Burkowski Jr. Xose Manuel Alvarino Social Studies Teacher Social Studies Teacher Miami-Dade County Miami-Dade County Academy for Advanced Academics at Hialeah Gardens Middle School Florida International University 11690 NW 92 Ave 11200 SW 8 St. Hialeah Gardens, FL 33018 VH130 Telephone: 305-817-0017 Miami, FL 33199 E-mail: [email protected] Telephone: 305-348-7043 E-mail: [email protected] For information concerning IMPACT II opportunities, Adapter and Disseminator grants, please contact: The Education Fund 305-892-5099, Ext. 18 E-mail: [email protected] Web site: www.educationfund.org - 1 - INTRODUCTION Students are entertained and acquire knowledge through images; Internet, television, and films are examples. Though the printed word is essential in learning, educators have been taking notice of the new visual and oratory stimuli and incorporated them into classroom teaching. The purpose of this idea packet is to further introduce teacher colleagues to this methodology and share a compilation of films which may be easily implemented in secondary social studies instruction. Though this project focuses in grades 6-12 social studies we believe that media should be infused into all K-12 subject areas, from language arts, math, and foreign languages, to science, the arts, physical education, and more. In this day and age, students have become accustomed to acquiring knowledge through mediums such as television and movies. Though books and text are essential in learning, teachers should take notice of the new visual stimuli. Films are familiar in the everyday lives of students. -
Understanding Autism
Introduction As a parent, you may have many questions regarding diagnosis. As you look for answers, you may encounter information about autism, its causes, and possible treatments. All of these different opinions can make it challenging for a family to organize options and begin to choose a treatment plan that best fits the family. We hope that this packet will help better prepare you to understand the information you receive about treatments for autism, as well as give you the chance to look over the most recent professional opinions about autism. Westside Regional Center anticipates supporting your family as you proceed from your lifetime. What is Autism? How and why did my child develop autism Unfortunately, no apparent cause exists for most cases, but most experts believe that autism is primarily a genetic condition. For about 10% of cases, experts believe that autism has either a specific genetic (from parent to child) or environmental cause. For example, there is an increased risk for autism from specific genetic disorders such as Fragile X Syndrome, Angelman Syndrome, Tuberous Sclerosis, Rh untreated Phenylketonuria, and some chromosome abnormalities. Known environmental causes include taking thalidomide during pregnancy (a type of sedative now not routinely available in the United States) or having German measles (rubella) during pregnancy. There are three main behaviors that are found in all children with autism: 1. Difficulty with social interaction: Children with autism may not be able to relate easily to people, have a hard time playing with other children, or have certain behaviors, such as avoiding eye contact or making socially inappropriate gestures in conversation.