JOURNAL OF VIROLOGY VOLUME 63 * DECEMBER 1989 NUMBER 12 Arnold J. Levine, Editor in Chief Robert A. Lamb Editor (1992) (1994) Northwestern University Princeton University Stephen P. Goff, Editor (1994) Evanston, Ill. Princeton, N.J. Columbia University Michael B. A. Oldstone, Editor (1993) Joan S. Brugge, Editor (1994) New York, N. Y. Scripps Clinic & Research University ofPennsylvania Peter M. Howley, Editor (1993) Foundation Philadelphia, Pa. National Cancer Institute La Jolla, Calif. Bernard N. Fields, Editor (1993) Bethesda, Md. Thomas E. Shenk, Editor (1994) Harvard Medical School Princeton University Boston, Mass. Princeton, N.J. EDITORIAL BOARD Rafi Ahmed (1991) Emanuel A. Faust (1990) Robert A. Lazzarini (1990) William S. Robinson (1989) James Alwine (1991) S. Jane Flint (1990) Jonathan Leis (1991) Bernard Roizman (1991) David Baltimore (1990) William R. Folk (1991) Myron Levine (1991) John K. Rose (1991) Amiya K. Banerjee (1990) Donald Ganem (1991) Arthur D. Levinson (1991) Naomi Rosenberg (1989) Tamar Ben-Porat (1990) Costa Georgopolous (1989) Maxine Linial (1991) Roland R. Rueckert (1991) Kenneth I. Berns (1991) Walter Gerhard (1989) David M. Livingston (1991) Norman P. Salzman (1990) Joseph B. Bolen (1991) Mary-Jane Gething (1990) Douglas R. Lowy (1989) Charles E. Samuel (1989) Michael Botchan (1989) Joseph C. Glorioso (1989) Malcohm Martin (1989) Priscilla A. Schaffer (1990) Thomas J. Braciale (1991) Larry M. Gold (1991) Robert Martin (1990) Sondra Schlesinger (1989) Dalius J. Briedis (1991) Hidesaburo Hanafusa (1989) Warren Masker (1990) Robert J. Schneider (1991) Michael J. Buchmeier (1989) John Hassell (1989) James McDougall (1990) Bart Sefton (1991) Robert Callahan (1991) William S. Hayward (1990) Thomas Merigan (1989) Bert L. Semler (1989) Barrie J. Carter (1990) Ari H. Helenius (1990) Lois K. Miller (1991) Charles J. Sherr (1990) Sherwood Casjens (1990) Roger Hendrix (1990) Peter Model (1989) Saul J. Silverstein (1991) Bruce Chesebro (1991) James M. Hogle (1991) Bernard Moss (1989) Patricia G. Spear (1990) John M. Coffin (1989) John J. Holland (1990) Brian R. Murphy (1991) Mark F. Stinski (1989) Gary H. Cohen (1991) Kathryn V. Holmes (1991) Opendra Narayan (1991) James Strauss (1990) Charles N. Cole (1989) Nancy Hopkins (1989) Joseph R. Nevins (1991) F. William Studier (1990) Peter L. Collins (1991) Alice S. Huang (1990) Erling Norrby (1989) Bfi Sugden (1990) Neal Copeland (1989) Steve Hughes (1991) Nancy G. Nossal (1990) John M. Taylor (1990) Donald Court (1990) Eric Hunter (1990) Dennis O'Callaghan (1989) Howard M. Temin (1991) Richard Courtney (1989) Tony Hunter (1989) Joseph Pagano (1990) David A. Thorley-Lawson (1991) Clyde S. Crumpacker II Richard Hyman (1989) Peter Palese (1991) Inder Verma (1989) (1991) Nancy Jenkins (1989) Enzo Paoletti (1991) Luis V. Villarreal (1991) Bryan R. Cullen (1990) Richard A. Katz (1990) Takis Papas (1990) Volker M. Vogt (1990) Thomas Curran (1991) Jack D. Keene (1991) J. Thomas Parsons (1989) Edward K. Wagner (1989) Samuel Dales (1991) Thomas J. Kelly (1991) Ulf G. Pettersson (1989) Gail Wertz (1991) Daniel DiMaio (1991) Eli Keshet (1990) Lennart Philipson (1990) Reed B. Wickner (1991) Walter Doerfler (1989) Elliott Kieff (1990) Lewis I. Pizer (1990) Eckard Wimmer (1991) Elvera Ehrenfeld (1989) Daniel F. Klessig (1991) Carol Prives (1989) Owen Witte (1989) Robert N. Eisenman (1991) David Knipe (1991) Vincent Racaniello (1990) Charles Hamish Young (1989) Suzanne U. Emerson (1989) Daniel Kolakofsky (1989) R. Frank Ramig (1991) Harald zur Hausen (1989) Lynn W. Enquist (1991) Hsing-Jien Kung (1990) Dan S. Ray (1989) Mary K. Estes (1989) Ching-Juh Lai (1990) Solon L. Rhode (1989) Ellen Fanning (1991) Michael Lai (1991) Harriet Robinson (1991)

Helen R. Whiteley, Chairman, Publications Board Linda M. Illig, Managing Editor, Journals Judith Nedrow, Production Editor

The Journal of Virology (ISSN 0022-538X), a publication of the American Society for Microbiology, 1325 Massachusetts Ave., N.W., Washington, DC 20005, is devoted to the dissemination of fundamental knowledge concerning viruses of bacteria, plants, and animals. Investigators are invited to submit reports of original research in all areas of basic virology, including biochemistry, biophysics, genetics, immunology, morphology, physiology, and pathogenesis and immunity. Instructions to authors are published in the January issue each year; reprints are available from the editors and the Publications Department. The Journal is issued monthly, one volume per year. The nonmember subscription price is $350 per year; single copies are $30. The member subscription price is $41 (foreign, $71 [air drop shipping]) per year; single copies are $8.00. Correspondence relating to subscriptions, reprints, defective copies, availability of back issues, lost or late proofs, disposition of submitted manuscripts, and general editorial matters should be directed to the ASM Publications Department, 1325 Massachusetts Ave., N.W., Washington, DC 20005 (phone: 202 737-3600). Claims for missing issues from residents of the United States, Canada, and Mexico must be submitted within 3 months after publication of the issues; residents of all other countries must submit claims within 6 months of publication of the issues. Claims for issues missing because offailure to report an address change or for issues "missing from files" will not be allowed. Second-class postage paid at Washington, DC 20005, and at additional mailing offices. POSTMASTER: Send address changes to Journal of Virology, ASM, 1325 Massachusetts Ave., N.W., Washington, DC 20005. Made in the U.S.A. Printed on acid-free paper. Copyright ©3 1989, American Society for Microbiology. i9W,& r4{U (I1'4I,t All Rights Reserved. The code at the top of the first page of an article in this journal indicates the copyright owner's consent that copies of the arti- cle may be made for personal use or for personal use of specific clients. This consent is given on the condition, however, that the copier pay the stated per-copy fee through the Copyright Clearance Center, 21 Congress St., Salem, MA 01970, for copying beyond that permitted by Sections 107 and 108 of the U.S. Copyright Law. This consent does not extend to other kinds of copying, such as copying for general distribution, for advertising or promotional purposes, for creating new collective works, or for resale. Author Index

Abe, Shinobu, 5354 Frey, Alan B., 5440 Lahn, Sharon, 5194 Rice, Nancy R., 5194 Ahlquist, Paul, 5302 Fu, Jianlin, 5492 Lai, Ching-Juh, 5086 Richards, Douglas, 5302 Ahn, Jeong K., 5425 Lai, Michael M. C., 5285 Righthand, V. Fay, 5268 Anderson, Mary E., 5175 Gallo, Michael L., 5023 Langdon, Wallace Y., 5420 Robey, W. Gerard, 5046 Arias, Carlos F., 5393 Gallo, Robert C., 5046 Langlois, Alphonse J., 5046 Roos, Raymond P., 5344, 5492 Arita, Mineo, 5354 Gao, Min, 5258 Lawson, T. Glen, 5013 Rose, John K., 5328 Arthur, Larry O., 5046 Garber, Christa, 5119 Le, Shu-Yun, 5006 Rosenblum, Betsy, 5364 Ayata, Minoru, 5464 Garcia, Gabriela, 5393 Leis, Jonathan, 5319 Rossignol, Jean-Michel, 5451, Garoff, Henrik, 4991, 5111 Lequarre, Anne-Sophie, 5194 5497 Baier, Michael, 5119 Garsky, Victor M., 5037 Levine, Arnold J., 5440 Ruusala, Aino, 5328 Bennett, Ellen R., 5371 Gavin, Brian J., 5425 Levis, Robin, 5216 Ben-Porat, Tamar, 5475 Gazzolo, Louis, 5413 Linial, Maxine L., 5092 Salhi, Samia, 5497 Berkhout, Ben, 5501 Ghattas, Ingrid, 5310 Lippe, Roger, 5133 Schaller, Heinz, 5399 Bernard, Alain, 5413 Graham, Frank L., 5133 Liu, Qingyun, 5062 Schlesinger, Sondra, 5310 Bess, Julian W., Jr., 5046 Grakoui, Arash, 5216 Lopez, Susana, 5393 Schlicht, Hans-Jurgen, 5399 Biegalke, Bonita J., 5092 Gruffat, Henri, 5276 L6pez-Turiso, Jose Angel, Schulze, Thomas, 5489 Blackburn, Robert V., 5268 Grumont, Raelene J., 5420 5445 Semler, Bert L., 5344, 5492 Boere, Wil A. M., 4991 Grundy, Frank J., 5101 Lowy, Douglas R., 5469 Bolen, Joseph B., 5076 Grunhaus, Avraham, 5455 Sergeant, Alain, 5276 Bray, Michael, 5086 Maizel, Jacob, 5006 Sexton, Connie J., 5505 Brunner, Dieter, 5483 Hacker, David, 5166 Makino, Shinji, 5285 Shaw, Andrey, 5328 Buisson, Monique, 5276 Haddad, Ruwaida S., 4998 Malim, Michael H., 5006 Siddiqui, Aleem, 5293 Bukowski, Jack F., 5086 Haenni, Anne-Lise, 5153 Manet, Evelyne, 5276 Skalka, Anna Marie, 5319 Hagino-Yamagishi, Kimiko, Martinez, Concepci6n, 5445 Smith, Lisa L., 5013 Callahan, Pia L., 5037 5354, 5386 McBride, Alison A., 5076 Sodora, Donald L., 5184 Capone, John P., 5509 Hartle, Heather T., 5054 Metsikko, Kalervo, 5111 Spector, Deborah H., 5334 Carlier, Damien, 5497 Hartung, Susanne, 5119 Mettenleiter, Thomas C., 5475 Srinivasan, Ashok, 5459 Casey, James W., 5194 Harty, Ronald N., 5101 Moelling, Karin, 5489 Stacy, Terryl, 5208 Chamberlain, Michele, 5208 Hassell, John A., 5371 Mondesert, G., 5124 Stein, Steven, 5492 Chen, Chu, 5092 Hauber, Joachim, 5006 Morch, Marie-Dominique, Steinhauer, David A., 5030 Cichutek, Klaus, 5119 Hirano, Akiko, 5464 5153 Stephens, Robert M., 5194 Clarke, David, 5030 Holland, John J., 5030 Morin, Nathalie, 5228 Sugg, Nancy, 5475 Cohen, Gary H., 5184 Honda, Ayae, 5142 Morse, Herbert C., III, 5420 Sugimura, Haruhiko, 5405 Cohen, Jeffrey I., 5364 Horwitz, Marshall S., 5244, Muller, Carolin, 5119 Summers, William C., 5062 Cole, Charles N., 5208 5455 Murdin, Andrew D., 5251 Szafranski, Przemyslaw, 5153 Colle, Clarence F., 5101 Howley, Peter M., 5076 Colonno, Richard J., 5037 Huang, Henry V., 5216 Nara, Peter L., 5046 Tago, Katsuhiko, 5354 Cordingley, Michael G., 5037 Hutt-Fletcher, Lindsey M., Naujokas, Monica, 5371 Tang, Wei-Jen, 5478 Crise, Bruce, 5328 4998 Nitschko, Hans, 5310 Tegtmeyer, Peter, 5175 Crumpacker, Clyde S., 5023 Hyland, Craig D., 5420 Nomoto, Akio, 5354, 5386 Thach, Robert E., 5013 Cullen, Bryan R., 5006 Ticehurst, John, 5364 Iizuka, Narushi, 5354 O'Callaghan, Dennis J., 5101 Traynor, Patricia, 5302 Dai, Hong Yan, 5201 Ikeda, Hidetoshi, 5405 Ohara, Yoshiro, 5492 Trescol-Biemont, de Haro, Cdsar, 5445 Ishihama, Akira, 5142 O'Neill, Robert E., 5069 Marie-Claude, 5276 de la Luna, Susana, 5445 Isom, Harriet, 5293 Ortfn, Juan, 5445 Tsui, Shanli, 5175 de la Torre, Juan Carlos, 5030 Ou, Jing-hsiung, 5238 Tsuruoka, Hiroshi, 5464 Delsert, Claude, 5228 Jameel, Shahid, 5293 de Recondo, Anne-Marie, Jansen-Durr, P., 5124 Pagano, Joseph S., 5505 5451, 5497 Jeang, Kuan-Teh, 5501 Palese, Peter, 5142 Valcarcel, Juan, 5445 Diringer, Heino, 5489 Jean-Jean, Olivier, 5451, 5497 Palmenberg, Ann C., 5013 Vass, William C., 5469 Domingo, Esteban, 5030 J0rgensen, Poul, 5201 Paludan, Kirsten, 5201 Velu, Thierry J., 5469 Dorsky, David I., 5023 Papas, Takis S., 5119 Drugeon, Gabriele, 5153 Katz, Richard A., 5319 Parris, Deborah S., 5023 Wahlberg, Johanna M., 4991 Duarte, Elizabeth, 5030 Katzman, Michael, 5319 Parvin, Jeffrey D., 5142 Ward, David C., 5425 Duc Dodon, Madeleine, 5413 Kedinger, C., 5124 Patel, Nita U., 5293 Waters, David J., 5046 Duch, Mogens, 5201 Kelliher, John C., 5046 Peden, Keith W. C., 5459 Weimer, Thomas, 5451 Durand, Benedicte, 5276 Kjeldgaard, Niels Ole, 5201 Pedersen, Finn Skou, 5201 Weiss, Barbara, 5310 Klessig, Daniel F., 5228 Pedersen, Niels C., 5483 Werner, Albrecht, 5119 Edwards, John, 5194 Klucher, Kevin M., 5334 Pelaez, Fernando, 5445 Werstuck, Geoff, 5509 Eisenberg, Roselyn J., 5184 Knipe, David M., 5258 Pettit, Steven C., 5244 Wigdahl, Brian, 5054 Eisenman, Robert N., 5092 Kohara, Michinori, 5354 Pipas, James M., 5459 Will, Hans, 5451 Elie, Christiane, 5497 Kolakofsky, Daniel, 5159, Purcell, Robert H., 5364 Wimmer, Eckard, 5251 El Kholy, Mohamed A., 5455 5166 Pyle, Stephen W., 5046 Wong, Timothy C., 5464 Engler, Jeffrey A., 5244 Komatsu, Toshihiko, 5354 Wright, Rebecca, 5310 Ennis, Francis A., 5086 Kong, Wing-Pui, 5344 Rabert, Douglas K., 5334 Kraus, Gunter, 5119 Racaniello, Vincent R., 5069 Falgout, Barry, 5086 Krohn, Kai, 5046 Raju, Latha, 5159 Yamanouchi, Kazuya, 5464 Feinstone, Stephen M., 5364 Kroner, Philip, 5302 Raju, Ramaswamy, 5159, Yeh, Chau-ting, 5238 Feldman, Ricardo A., 5469 Krystal, Mark, 5142 5166, 5216 Yen, T. S. Benedict, 5238 Fenrick, Randy, 5006 Kumar, Gyanendra, 5425 Raviprakash, Kanakatte S., Yoshikawa, Yasuhiro, 5464 Ferdinand, Franz J., 5119 Kunsch, Charles, 5054 5455 Fischinger, Peter J., 5046 Kurane, Ichiro, 5086 Register, R. Bruce, 5037 Zagouras, Panayiotis, 5328 Folk, William R., 5478 Kurth, Reinhard, 5119 Rice, Charles M., 5216 Zsak, Laszlo, 5475 1990 APPLICATION FOR FULL MEMBERSHIP IN THE AMERICAN SOCIETY FOR MICROBIOLOGY 1325 Massachusetts Avenue, NW * Washington, D.C 20005 * (202) 737-3600 * FAX (202) 737-0367 Eligibility ASM welcomes to full membership anyone who is interested in its objectives and has a minimum of a bachelor's degree or equivalent in microbiology or a related field. Initiation Memberships are initiated and renewed in January each year. 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0. TOTAL (Sum of E, P1 and 2-should equal net prss run shown in A) 6,025 6,000 Signtu And of Editor, or Owner 11.I certify that the statements made by Tltle Publisher, Business Manager, me above are correct and complete i4L, PS FormASFar3262,,56Feb.Fe.15,Se,ntutos1989 (See instructlins onnrrereversc) AUTHOR INDEX VOLUME 63

Aaronson, Stuart A., 3080 Baack, Martina, 2820 Bernstein, Alan, 2844 Brown, Jay C., 3777, 4697 Aasted, Bent, 9 Babiss, Lee E., 2709 Berry, Brian T., 2379 Brown, Lorena E., 3087, 3545 Abe, Shinobu, 1302, 5354 Babiuk, Lorne A., 1916, 2159 Berthelot, Nicole, 523, 2169 Brown, Thomas L., 1612 Abmayr, Susan M., 1869 Bacon, Larry D., 504 Bess, Julian W., Jr., 5046 Brubaker, Jeffrey O., 4969 Ace, Chris I., 2260 Badger, John, 2476 Beyer, Harry, 456 Bruenn, Jeremy A., 3983 Achacoso, Joseph A., 4331 Baer, M., 3622 Bhat, Ramesh A., 3423 Bruggemann, Ute, 3519 Adachi, Akio, 4110 Baglioni, Corrado, 2785 Biberfeld, Gunnel, 3376 Brunner, Dieter, 5483 Adami, Guy R., 85 Bagnis, Claude, 513 Bieberich, Charles, 1891 Bruszewski, Joan, 2680 Aderem, Alan, 2929 Baichwal, Vijay R., 2469 Biegalke, Bonita J., 5092 Bubb, Vivien, 4417 Agol, Vadim I., 4034 Baier, Michael, 5119 Bielinska, Anna, 4097 Bucher, Doris J., 1239, 3622 Ahlquist, Paul, 4545, 5302 Bailly, Catherine, 4317 Billaud, M., 4121 Buchmeier, Michael J., 175 Ahn, Byung-Yoon, 226 Baker, Carl C., 3529 Billy, Helmuth T., 148 Buck, Charles D., 4498 Baker, Jean C., 1054 Birkenbach, Mark, 4079 Buckland, Robin, 4965 Ahn, Jeong K., 5425 Baker, Susan C., 3693 Biswas, Siddhartha K., 392 Buckler-White, Alicia J., Aiken, Judd M., 1686 Balachandran, N., 970, 2835 Black, Donald N., 4703 3595, 4919 Aizawa, Shinichi, 3185 Balachandran, Raghavan, 2361 Black, Tracy L., 2244 Buisson, Monique, 607, 5276 Akaike, Takaaki, 2252 Baldwin, Betty, 1360, 4665 Blackburn, Robert V., 5268 Bukowski, Jack F., 4969, 5086 Albert, Laura, 1959 Bale, James F., Jr., 2667 Blaese, R. Michael, 3865 Burge, T., 2790 Albrecht, Mary A., 1861 Ball, L. Andrew, 4767 Blair, Donald G., 205, 2959 Burghoff, Robert, 1 Alexander, Nancy J., 4277 Ballard, Dean W., 1578, 3213 Bloom, Marshall E., 9 Burk, Robert D., 4069 Alexandersen, Soren, 9 Baltera, Robert F., Jr., 4441 Blundell, Matthew C., 4814 Burke, Rae Lyn, 2951 Allan, Brenda J., 1587 Baltimore, David, 3708 Boccara, M., 2169 Burkhardt, Janis K., 659 Allen, George, 4189 Bandyopadhyay, Pradip K., Bodkin, Dinah K., 1188, 4676 Burnett, Stanley, 2215 Almond, Jeffrey W., 1338 2847 Bodnar, John W., 3651, 4344 Burns, Cara Carthel, 4866 4949 Bankowski, Matthew J., 1981 Bodner, Anne J., 1400 Burns, John W., 4553 Aloni, Yosef, 1134, 4093 Bannigan, John G., 4027 Bodor, Josef, 1015 Burny, A., 952 Alonso, Miguel A., 1354 Bapat, Ashok R., 1400 Bodwell, Teresa, 4469 Burstein, Haim, 4325 Alper, D., 2557 Barbone, Francis, 1695 Boere, Wil A. M., 4991 Busson, P., 4121 Alves, Kenneth, 2366 Barbosa, Miguel S., 1404 Bogard, Connie L., 759, 2893 Butel, Janet S., 3961 Amanuma, Hiroshi, 4824 Barile, Giuseppe, 828 Bogerd, H., 1578 Byrn, Randal A., 1861, 3489, Amati, P., 4890 Barker, Kathleen, 2929 Boggs, Tina, 2680 3708, 4370 Amelse, Roberta E., 2835 Barnett, Jim W., 1661 Bohnlein, Ernst, 1578, 3213 Byrnes, Julie, 1010 Amouyel, Philippe, 3382 Barnier, Jean Vianney, 481 Bohnlein, Sabine, 421 Amrein, M., 2233 Baroudy, Bahige M., 1612 Bolen, Joseph B., 753, 2343, Cadwallader, Karen, 1031 Anaraki, Farvardin, 2300 Barr, Philip J., 3176 5076 Cahill, Karyn B., 3634 Anders, E. Margot, 2758, 3087 Barrell, Bart, 1345 Bollag, Brigitte, 863 Cahour, Annie, 4199 Anderson, Mary E., 5175 Barrett, Nancy L., 85 Bona, Constantin, 2674 Cai, Weizhong, 730, 4579 Anderson, Stacie, 3865 Barsoum, James, 4422 Bonelli, Fabrizio, 4645 Calender, Alain, 615 Anderson, W. French, 3865 Bartenschlager, Ralf, 2995 Boni, Jurg, 4088 Callahan, Pia L., 36, 5037 Ando, Masayuki, 2252 Barthelemy, Isabel, 460 Bonneau, Robert H., 1480 Callahan, Robert, 4982 Androphy, Elliot J., 1775, Basak, Sukla, 3164 Boone, Lawrence R., 2592 Calothy, Georges, 481 2340, 4422 Baseler, M., 4626 Booy, Frank P., 3777 Calzada, Pablo J., 4808 Ansell, David M., 4703 Bates, Robert C., 3180 Boral, Anthony L., 76 Cameron, Janet M., 2260 Antonucci, Tammy K., 579 Bathurst, Ian C., 3176 Bos, Johannes L., 1470, 4039 Cammack, Nicholas, 4949 Aparisio, Diane I., 2847 Baumann, Raymond P., 1275 Bose, Henry R., Jr., 1107 Campos, M., 1916 apRhys, Colette M. J., 2798 Bavand, Michael, 1019 Bosselman, Robert A., 2680 Cann, Alan J., 1474 Araki, Shukuro, 2252 Baxt, B., 2143 Botchan, Michael, 1743 Capon, Daniel J., 4370 Argon, Yair, 659 Baylor, Norman W., 3586 Bouloy, Michele, 4199 Capone, John P., 5509 Arias, Carlos F., 5393 Beard, Peter, 2510 Bourachot, Brigitte, 2567 Cardiff, Robert D., 148 Beaton, Ann, 4450 Bourre, F., 4520 Carlier, Damien, 5497 Arita, Mineo, 1302, 5354 Beck, Melinda A., 4148 Boyd, Branin A., 2497 Carlson, Jonathan O., 2737 Arrand, John R., 983 Bedell, Mary A., 1247 Bradley, Guy, 2534, 4129 Carmichael, Ellen P., 591 Arrigo, Salvatore J., 4875 Beeler, Judy A., 2941 Bradshaw, Gary L., 1695, 1704 Carmichael, Gordon G., 85, Arthur, Larry O., 5046 Belakebi, Mustapha, 513 Bradshaw, Harvey D., Jr., 432, 3634 Arthur, Ray R., 4445 Belardelli, Filippo, 2785 148 Carpenter, Susan, 2492 Arvin, Ann M., 2392 Bellett, Alan J. D., 303, 311 Brady, John, 2866 Carrasco, Luis, 1354, 4729 Asano, Yoshihiro, 3185 Bennett, Elizabeth J., 303 Brahic, Michel, 1101 Carrington, James C., 4459 Ashktorab, Hassan, 3034 Bennett, Ellen R., 5371 Braithwaite, Antony W., 1792 Carroll, Robert D., 4913 Askew, David, 2959 Bennett, L. Michelle, 1989 Brando, Lorraine V. Jones, Carstens, Eric B., 1587 Astell, Caroline R., 4814 Benoit, A., 4520 2278 Carter, Barrie J., 873 Athanassopoulos, Angelos, Ben-Porat, Tamar, 2690, 3323, Brandsma, Janet L., 957 Carter, J. J., 1525 1265 5475 Branton, Philip E., 987 Cartwright, Christine A., 3362 Atherton, Sally S., 4808 Berk, A. J., 3499 Bray, Michael, 2853, 5086 Caruso, M., 4890 Atkins, Gregory J., 4027 Berkhout, Ben, 5501 Brewster, Frank, 584 Casey, James W., 5194 Atwood, Walter J., 4474 Berman, Joan W., 1087 Bridge, Eileen, 631 Castaneda, Sharon J., 2977 Au, Kit-Sing, 4553 Berman, Phillip W., 3489 Britt, William J., 403, 1995 Caughey, Byron, 175 Auborn, Karen J., 912, 957 Bernard, Alain, 5413 Broker, Thomas R., 2967 Cebrian, Jose, 523, 2169 Aurelian, Laure, 2773, 3389 Bernard, Bruno A., 4317 Brookes, S., 1448 Celis, Esteban, 747 Austin, Joan B., 1460 Bernard, Hans-Ulrich, 1142, Brooks, L., 1967 Chajut, Ayelet, 2877 Avrameas, Stratis, 955 3261 Brown, Dennis T., 883, 1975 Chakrabarti, Lisa, 4395 Ayata, Minoru, 1162, 5464 Berns, Kenneth I., 4450 Brown, Edwin A., 4932 Challberg, Mark D., 196 i ii AUTHOR INDEX J. VIROL.

Chamberlain, Michele, 5208 Coelingh, Kathleen van Dambrine, Ginette, 1803 Dildine, Sandra L., 847 Chamow, Steven M., 4370 Wyke, 375, 2941, 3080, 3755 Daniel, Muthiah D., 1800, Dillon, Patrick J., 974 Chan, Hardy, 1661 Coen, Donald M., 759, 1839, 4709 DiMaio, Daniel, 259, 4515 Chan, Wai-Kit, 4553 2893, 4088 Darling, Allan, 3769 DiPaolo, J. A., 159 Chan, Woon-Khiong, 3261 Coffin, John M., 1763, 3301, Darmon, Michel, 4317 Diringer, Heino, 5489 Chang, Cheow K., 2835 3810 Das, Jyotirmoy, 392 Dobson, Anthony T., 3844 Chang, Chia-Pine, 281 Cohen, Gary H., 2325, 5184 Dasgupta, Asim, 4563, 4616, Doerfler, Walter, 1677, 3519, Chang, Chia-Ping, 3330 Cohen, J. John, 572 4689 3535, 3612 Chang, Chungming, 4011 Cohen, Jeffrey I., 5364 David, E. Thalia, 303 Doggett, David L., 2108 Ch'ang, Lan-Yang, 2746 Cohen, L., 2557 David, Sasson, 1116 Domingo, Esteban, 59, 2385, Chang, Long-Sheng, 3479, Cohen, Sara, 3416 Davies, Monique V., 1651 5030 3822 Cohn, Anders, 9 Davies, Peter, 1587 Dong, Hong, 2191 Chang, Ming-Fu, 3693 Cohrs, Randall J., 948 Davis, Stephen, 4189 Doniger, J., 159 Chang, Nancy T., 2550, 3579 Cole, Charles N., 4777, 5208 Dawson, Chandler R., 4756 Dora, Said, 2820 Chang, Tse-Wen, 2550, 3579 Cole, Georgette E., 3240 Deb, Sumitra, 2901 Dorney, D. J., 730 Chang, Yung-Nien, 2773 Colgrove, Robert, 4019 Deb, Swati Palit, 1310, 2901 Dorsky, David I., 5023 Chanock, Robert M., 1852, Colle, Clarence F., 5101 Debouck, Christine, 1569 Dougherty, Joseph P., 3209 2853 Collins, Peter L., 411, 2019 DeClue, Jeffrey E., 542 Dowhanick, Jennifer J., 3983 Chao, Mei, 1945, 4292 Colonno, Richard J., 36, 3444, Dedera, Douglas, 3205 Drake, Anne L., 2108 Charon, M., 3944 5037 DeFilippes, Frank M., 4060 Dreesman, Gordon R., 1549 Chattopadhyay, Sisir K., 1284 Compans, Richard W., 978, de Fromentel, Claude Caron, Drenckhahn, Detlev, 1677 Chavrier, Philippe, 607 1095, 2278, 3164 3894 Drillien, Robert, 1814 Chebath, Judith, 1116 Compton, Teresa, 3240 de Goede, Ruud E. Y., 2118 Drozdov, Sergei G., 4034 Chebloune, Yahia, 513 Condamine, Hubert, 2134 DeGrand, David, 3601 Drugeon, Gabriele, 5153 Chee, Mark, 1345 Condit, Richard C., 705, 714, de Haro, Cesar, 5445 Drummer, Heidi, 3087 Chen, Chiou-Rong, 4165 948 de Jong, Erik, 3368 Duarte, Elizabeth, 5030 Chen, Chu, 5092 Consigli, Richard A., 2881, de la Luna, Susana, 2385, Dubey, Lon, 4264 Chen, Ding-Shinn, 4165 3168 5445 Dubovi, Edward J., 3934 Chen, Irvin S. Y., 1474, 4404, Contag, Christopher H., 4362 DeLange, A. M., 2437 Duc Dodon, Madeleine, 5413 4875 Content, Jean, 2616 de la Torre, Juan Carlos, 59, Duch, Mogens, 5201 Chen, Jiandong, 2204 Contreras-Salazar, Bertha, 2063, 2072, 2385, 5030 Dudzik, Karla I., 3279, 3507 Chen, Katherine C., 3180 2768, 3135 Deleage, Gilbert, 4965 Duesberg, Peter H., 1377 Chen, Pei-Jer, 4165 Cook, James L., 3408 de Leij, Lou F. M. H., 1485 Duke, Gregory M., 1822 Chen, Yi-ming A., 4952 Cook, Margery L., 1153 Delgado, Teresa, 925 Dumont, Daniel J., 987 Cheng, Yung-chi, 1400 Cook, Tom, 4303 Delius, Hajo, 4911 Dunn, Glynis, 1338, 4949 Cherrington, Julie M., 1435 Coombs, David H., 2427 DeLoia, Julie A., 4069 Dunn, K. J., 205 Chervitz, Stephen A., 1420 Coombs, Kevin M., 883 Delree, P., 3155 Durand, Benedicte, 5276 Chesebro, Bruce, 175, 2492 Cooper, Neil R., 3991 Delsert, Claude, 2289, 5228 Dutko, Frank J., 2002, 2476 Chester, Nicholas, 3176 Copeland, Neal G., 3678 DeLuca, Neal A., 1203, 1861, Dynan, William S., 1420 Cheung, Andrew K., 2908 Copeland, Terry D., 1416, 3714 Cheung, Ramsey C., 2445 2543 Del Vecchio, Alfred M., 1514 Easterday, Bernard C., 3453 Cheung, Wing-Fai, 782 Corapi, Wayne V., 3934 Delwart, Eric L., 273 Eckels, Kenneth H., 2853 Chevallier-Greco, Anna, 607, Cordingley, Michael G., 5037 DeMarchi, Jean M., 2690 Eckhart, Walter, 3362 615 Cordonnier, Agnes, 4464 Dennis, Amy F., 3176 Edgell, Marshall H., 111 Childs, Geoffrey, 3200 Cosset, Francois-Loic, 513 Deppert, Wolfgang, 2308, 3926 Edmonds, Caroline, 2650 Chin, Michael T., 2967 Cote, Paul J., 1360 Depto, Alison S., 1232, 2699 Edmonson, Paul, 2036 Chittenden, Thomas, 3016 Cotmore, Susan F., 1002, Derbin, Claude, 3550 Edris, Wade A., 2861 Choe, Joonho, 1743 3902 de Recondo, Anne-Marie, Edwards, John, 5194 Chong, Lisa, 3569 Coulon, Patrice, 3550 5451, 5497 Egelman, E. H., 2233 Chong, Terrence, 1142 Countryman, Jill, 1721 Deshmane, Satish L., 943 Ehrenfeld, Ellie, 4866 Choo, Kong-Bung, 782 Courtney, Richard J., 3338 Desmettre, Philippe, 4189 Eichberg, Jorg W., 4292 Chou, Joany, 1059 Cova, Lucyna, 4965 Despres, Philippe, 4199 Eicher, Eva M., 4043 Chousterman, S., 2169 Craven, Rebecca C., 4331 Desrosiers, Ronald C., 1800, Eiden, Joseph, 2191 Chow, Louise T., 2967 Crawford, Sue E., 3974 3307, 4709 Eiden, Maribeth V., 2374 Chowdhury, Rukhsana, 392 Crise, Bruce, 5328 de Villiers, Ethel-Michele, Eisenberg, Roselyn J., 2325, Chuke, Wei-Fong, 863 Croissant, Odile, 4906 4898, 4911 5184 Chung, Theodore D., 2773, Croizier, Liliane, 1007 Devi-Rao, Gayathri, 3844 Eisenman, Robert N., 5092 3389 Cromlish, Wanda A., 1869 Dewalt, Patricia Gillis, 3444 Elango, Narayanaswamy, 411, Cichutek, Klaus, 1377, 5119 Crone, Donna Eisemann, 4172 Dewar, Robin L., 129, 2452 1413 Ciotta, Carmela, 4979 Cronin, Barbara, 303 de Wit, Catharina M., 4039 Eldor, Amiram, 4325 Cirone, Mara, 828 Crowell, Richard L., 3105 de Wolf, Frank, 2118 Elgizoli, Mohamed, 2921 Ciufo, Dolores M., 2798 Crumpacker, Clyde S., 5023 Deyerle, Karen L., 356 Elie, Christiane, 5497 Cladaras, Christos, 1265 Cullen, Bryan R., 421, 1181, Dezelee, Philippe, 481 El Kholy, Mohamed A., 5455 Clarke, Chester, 1010 3213, 5006 Diamond, Margaret E., 3983 Ellis, James, 2844 Clarke, David, 5030 Cullinane, Ann A., 1123 Diana, Guy, 2002 Emerman, Michael, 4395, Clavel, Francois, 1455 Culp, Jeffrey S., 1569 Diaz, Pamela S., 2392 4464 Clayson, Edward T., 1095, Cupelli, Lisa A., 1087 Dickson, C., 1448 Engels, Monika, 4882 2278 DiDonato, Joseph A., 3737 Engleman, Edgar G., 1451 Cleghon, Vaughn, 2289 Dai, Hong Yan, 5201 Diem, Kurt, 4945 Engler, Jeffrey A., 5244 Clemens, Dahn L., 2737 Dai, Ying, 2921 Dietzschold, B., 2885 Ennis, Francis A., 2486, 5086 Clements, Janice E., 1891, Dales, Samuel, 1540 Dfez, Juana, 59, 2385 Enquist, L. W., 250, 4055 3001 Dallo, Shatha, 4507 Diffoot, Nanette, 3180 Enrico, Amy, 2361 Cochrane, Alan W., 4438 Dalrymple, Joel M., 1619 Dikstein, Rivka, 919 Eppler, M., 2813 VOL. 63, 1989 AUTHOR INDEX iii

Ernberg, Ingemar, 3135 Fox, Elizabeth, 3651 Gessner, Andre, 1827 Grossman, Steven R., 366, Ernst, Darwin, 175 Frank, Ian, 4479 Gettie, Agegnehu, 4277 1247 Ertl, H. C. J., 2885 Franke, A. J., 2143 Geuskens, Maurice, 4797 Gruffat, Henri, 607, 615, 5276 Essex, Max, 4952 Franke, Christine A., 4285 Ghattas, Ingrid, 5310 Grumont, Raelene J., 5420 Esteban, Mariano, 997, 4507 Frankel, Wayne N., 1763, Ghosh, Ananta K., 4234 Grundy, Frank J., 5101 Estervig, David N., 2718 2623, 3810 Ghotbi, Zahra, 1891 Grunhaus, Avraham, 5455 Estes, Mary K., 2191, 3974, Franza, B. R., 1578 Giantini, Michael, 2415 Gruters, Rob A., 2118 4553 Fraser, Nigel W., 943 Gibson, Helen L., 3176 Guillon, Jean-Claude, 955 Etkind, Polly R., 4972 Frati, Luigi, 828 Gibson, Wade, 669 Guirakhoo, Farshad, 564 Evans, D. M. A., 1338 Fredholm, Merete, 4136 Giese, Neill, 3080 Gunkel, Kristin, 4882 Everett, Roger D., 2510, 3513 Fredrickson, Torgny N., 328, Gilbert, James H., 3240 Gunther, Magali, 1002 1223, 2411 Gilboa, Eli, 677 Guo, M., 912 Fadly, Aly M., 504 Freed, Deon D., 4459 Gillard, Sylvie, 1814 Guo, Peixuan, 4189 Faggioni, Alberto, 828 Freed, Eric O., 4670 Girard, Marc, 4199 Gupta, Kailash C., 974 Fahnestock, M. L., 1495, 2348 French, T. J., 3270 Gissmann, Lutz, 4907, 4911 Gupta, Phalguni, 2361 Fairman, Micaela P., 4181 French, Tracy W., 3934 Gius, David, 555 Gurney, Elizabeth G., 165, Faisst, Steffen, 2152 Frenkel, Niza, 4834 Glasgow, Gwendoline M., 2352 Faktor, Ouriel, 919 Frese, Knut, 1677 4027 Gurney, Theodore, Jr., 165 Falck-Pedersen, Erik, 532 Frey, Alan B., 5440 Gutkind, J. Silvio, 1715 Friderici, Karen, 776 Glass, Roger I., 2191 Falgout, Barry, 1852, 5086 Gliniak, Brian C., 3561, 4434 Guy, Bruno, 2270 Falk, Kerstin, 3135 Friedman, Harvey M., 4479 Friesen, Paul D., 493 Glorioso, Joseph C., 730 Fan, Hung, 2317, 3072 Gloss, Bernd, 1142 Hacker, David L., 776, 5166 Fancher, Marilyn J., 2002, Frisque, Richard J., 863, 901, Hackett, Perry B., 4787, 4986 2180, 4445 Glover, Paul L., 2592 2476 Gluzman, Yakov, 216, 4181 Haddad, Ruwaida S., 4998 Fang, Zhao-Yin, 2191 Fu, Jianlin, 5492 Hadzopoulou-Cladaras, Fujinami, Robert S., 1505, Goebel, Scott, 4189 Faras, Anthony J., 4904 Goetschy, 2616 Margarita, 1265 Farmerie, William G., 111 2081 Jean-Frangois, Haenni, Anne-Lise, 5153 Fujisawa, Jun-ichi, 3234 Goff, Stephen P., 319, 1558, Farrell, Michael J., 3844 2629 Haffar, Omar K., 3489 Farrell, Paul J., 3109 Fuller, A. Oveta, 3435 Haffey, Mary L., 2497, 4913 Fattaey, Ali R., 3168 Fuller-Pace, Frances V., 1938 Goldsborough, Mindy D., Haggerty, Sheryl, 2180 Fauci, A. S., 4626 Fung, Michael S. C., 3579 2829 Hagino-Yamagishi, Kimiko, Faulkner, Peter, 1393 Furtado, Manohar R., 3423 Golemis, Erica, 328 5354, 5386 Faure, Claudine, 513 Furuta, Yasuhide, 3185 Golub, Efim, 4438 Hahn, Chang S., 3459 Favre, Michel, 4905, 4906, Gombold, James L., 4525 Hahn, Young S., 1194, 3142 4909, 4910 Gabel, Christopher A., 4264 Gompels, U. A., 4744 Haider, Gabriele, 961 Feduchi, Elena, 1354 Gage, Philip J., 730 Gong, Shiaoching, 4507 Hall, Jennifer D., 2874 Feinstone, Stephen M., 5364 Gak, Eva, 2877 Gong, Y.-F., 3622 Hamamoto, Yoshiaki, 2504 Feitelson, Mark, 1019 Galindo, Jose, 3700 Gonzalez, Alvaro R., 4808 Hamburger, Judith, 4325 Felber, Barbara K., 1265 Gallahan, Dan, 4911 Gonzalez, Joseph, 2585 Hammarskjold, Bjorn, 1959 Feldman, Lawrence T., 3844 Galle, Peter R., 2598 Gonzalez-Scarano, F., 2527 Hammarskjold, Marie-Louise, Feldman, Ricardo A., 5469 Gallina, Andrea, 4645 Good, Peter J., 3884 1959 Felock, Peter J., 2002 Gallo, Michael L., 5023 Goodman, Jesse L., 1153 Hammer, Scott M., 1861 Felsani, A., 4890 Gallo, Robert C., 1416, 5046 Goodrich, Leo D., 137 Hammerschmidt, Wolfgang, Feng, Ya-Xiong, 2405, 2870 Galloway, Denise A., 809 Gordon, Wayne, 3579 2469 Fennie, Christopher, 639 Ganem, Don, 4019, 4257 Gore, M., 2885 Han, Shou-Hwa, 782, 4011 Fenrick, Randy, 3213, 5006 Gao, Min, 5258 Gorelick, Robert J., 2870 Hanafusa, Hidesaburo, 2461, Fenyo, Eva-Maria, 3376 Garber, Christa, 5119 Gorny, Miroslaw K., 2674 2929 Ferdinand, Franz J., 5119 Garcia, Gabriela, 5393 Gorziglia, Mario, 4101 Hanecak, Ronnie C., 2317 Fernandez-Tomas, Carlos, Garcia, Joseph, 2585, 4616 Gottlinger, Heinrich, 4085 Hansen, Mogens, 9 3858 Garcia, Juan Antonio, 2457 Goudsmit, Jaap, 2118 Hanson, Phyllis I., 4344 Feuer, Gerold, 2317 Garcfa-Arenal, Fernando, Gounon, Pierre, 2134 Hara, Kazuya, 3195 Ffrench, Rosemary A, 3087 2198 Gouvea, Vera, 2191 Hara, Takahiko, 182 Fiedler, Marlies, 4907 Garcia-Barreno, Blanca, 925 Gowda, Shantharaj D., 1451 Hardwick, J. Marie, 3040 Fields, Bernard N., 1188, Gardner, Sylvia D., 901 Graessmann, Adolf, 2820 Hardwicke, Mary Ann, 4590 4676, 4840, 4850 Gariglio, Patricio, 3858 Graham, Frank L., 5133 Hardy, W. Reef, 4653 Finberg, Robert, 4157 Garoff, Henrik, 4991, 5111 Grakoui, Arash, 1194, 5216 Harouse, Janet M., 2527 Finerty, S., 1967 Garsky, Victor M., 5037 Graslund, Astrid, 3769 Harper, Linda, 2690 Finlay, Cathy, 739 Gavin, Brian J., 5425 Grassmann, Ralph, 1818 Harrich, David, 2585 Finne, Jukka, 4409 Gaynor, Richard, 2585, 4616 Greaves, R., 1641 Harris, Ruth A., 3513 Fischinger, Peter J., 5046 Gazit, Arnona, 2877, 4925 Green, Maurice, 3516, 4962 Hartle, Heather T., 2527, 5054 Fitzpatrick, D. R., 1916 Gazzolo, Louis, 5413 Green, Patrick L., 1989 Hartley, Janet W., 328, 1223, Flack, Alma M., 4027 Gearhart, John D., 4069 Greenberg, Harry B., 1661, 1460, 2411 Flamand, Anne, 3550 Gebhard, John, 4303 2445, 3279 Hartung, Susanne, 5119 Flanagan, W. Michael, 3844 Geck, Peter, 1010, 3601 Greene, W. C., 1578 Harty, Ronald N., 5101 Fleckenstein, Bernhard, 1818 Geerts, Dirk, 1408 Gregory, Francoise, 2343 Haseltine, William A., 1, Fluck, Michele M., 776 Geliebter, J., 952 Gregory, Timothy J., 3489, 1604, 2857, 4085, 4115 Fogarty, Steven J., 1669 Gelman, Irwin H., 2461 4370 Hassell, John A., 5371 Folan, Jean C., 4027 Gerin, John L., 1360, 1612 Griot, C., 2790 Hasson, Tama B., 3612 Folk, William R., 242, 5478 Gershon, Anne A., 4264 Groner, Albrecht, 1677 Hatanaka, Masakazu, 1465 Fortney, James, 2699 Gershon, Michael D., 4264 Groopman, Jerome E., 3489, Hatfield, Dolph L., 2405, 2870 Forzani, Barbara, 1612 Gershon, Paul D., 4703 3708, 4370 Hattori, Seisuke, 182 Fournel, Jean-Jacques, 2270 Geryk, Josef, 481 Grose, Charles, 3912 Hauber, Joachim, 421, 1181, Fowlkes, Dana M., 3423 Gessani, Sandra, 2785 Grosfeld, Haim, 3416 3213, 5006 iv AUTHOR INDEX J. VIROL.

Hauser, Charlotte, 1677 Hoxie, James A., 2527 Jenison, Steven A., 809 Kenney, Shannon, 1729, 3870, Hay, Kathleen A., 2861 Hruby, Dennis E., 2726, 4285 Jenkins, John R., 1792, 3894 3878 Hayashi, Masanobu, 2534 Hrynko, Tamara A., 1023 Jenkins, Nancy A., 3678 Kestler, Harry W., III, 4709 Hayashi, Yasuyuki, 2936 Hsu, Kuo-Hom Lee, 3105 Jennings, Myra, 4277 Ketner, Gary, 624, 631 Hayward, Gary S., 2773, 2798 Hsu, Rou-Yin, 2680 Jennings, Stephen R., 1480 Khalili, Kamel, 463 Hayward, S. Diane, 101, 3040 Hu, Sylvia, 2680 Jia, Ran, 3761 Kieff, Elliott, 933, 1031, 4051, Hearing, Patrick, 2605, 3057 Hu, Wen, 3205 Jochemsen, Aart G., 4039 4079 Heilbronn, Regine, 3683 Huang, D., 4121 Johansson, Bert E., 1239 Kieny, Marie-Paule, 2270 Heilman, Conrad J., 2325 Huang, Henry V., 5216 Johnson, Jennifer S., 4370 Kiessling, Udo, 2215 Heimer, Jessica, 1959 Huang, Jau-Ling, 4011 Johnson, Moira A., 2048 Kilbourne, Edwin D., 1239 Heinz, Beverly A., 2476 Huang, Min-Mei, 2605 Johnson, Raymond M., 819 Kim, Sunyoung, 3708 Heinz, Franz X., 564 Huang, Shau-Ku, 4242 Johnston, Robert E., 1619 Kimura, Genki, 3748 Henderson, Louis E., 2543 Hubbert, Nancy L., 3151 Jolicoeur, Paul, 2088 King, George L., 1318 Hendrickx, Andrew G., 4277 Huisman, Han G., 2118 Jolly, P. E., 1811, 4682 Kingsley, David M., 3678 Henning, Ulf, 3472 Humphries, Eric H., 1630 Joly, Etienne, 1845, 4303 Kim, Andre, 1814 Hensel, Charles H., 4986 Hung, Tao, 2191 Jondal, Mikael, 3376 Kishida, Yoshiko, 4110 Herbomel, Philippe, 2567 Hunninghake, G. W., 3026 Jones, C. Hal, 101 Kishimoto, Hidehiro, 3185 Herrlich, Peter, 4540 Hunter, John J., 1049 Jones, Katherine H., 1247 Kitado, Haruo, 3072 Hess, Jay L., 1891, 3001 Hunter, Tony, 398 Jones, Nicholas C., 4047 Kiyomasu, Takahiro, 4110 Hesselton, Ruth, 3601 Huq, Afroza, 4569 Jones, Stephen N., 1833 Kjeldgaard, Niels Ole, 5201 Heyden, Nancy Vander, 3205 Husak, Paul, 1695 Jorgensen, Poul, 5201 Klavinskis, Linda S., 4311 Hicks, Karen A., 759, 2893 Huso, D. L., 1811 Joseph, Bridget, 1416 Klein, George, 2768, 3135 Higashi, Kazuhiro, 3161 Hutchison, Clyde A., III, 111 Joung, Keith, 1 Kleiner, Eva, 1775 Highlander, Steven L., 730 Hutchison, Keith W., 4043 Judd, A., 3622 Klenk, Hans-Dieter, 1677 Higuchi, Ikuko, 4110 Hutt-Fletcher, Lindsey M., Juttermann, Ruth, 3535 Klessig, Daniel F., 2289, 4376, Hikikoshi, Atsuko, 3185 4998 5228 Hinds, Philip, 739, 790 Hyland, Craig D., 5420 Kabat, David, 3561, 4434, 4958 Kliewer, Steven, 4616 Hinkula, J., 3525 ladarola, Michael, 1737 Kadison, Paula, 1604 Klimkait, Thomas, 3784 Hino, Okio, 2638 Ianconescu, Marius, 2877 Kaehler, Donal A., 1989 Klinken, S. Peter, 1489, 2411 Hinshaw, Virginia S., 3453 Ibaraki, Tamotsu, 3669 Kahn, Tomas, 4911 Klock, Gerd, 3261 Hirano, Akiko, 1162, 5464 Igietseme, Joseph U., 4808 Kakunaga, Takeo, 1174 Klucher, Kevin M., 5334 Hirsch, Russell, 4257 Ihle, James N., 2959 Kamine, James, 1729, 3870 Knipe, David M., 759, 2893, Hirsch, Vanessa, 2108 lizuka, Narushi, 5354 Kan, N., 205 3399, 5258 Hiscott, J., 2557 Ikawa, Yoji, 2226, 3185, 4824 Kanda, Tadahito, 965 Knippers, Rolf, 2820 Hizi, Amnon, 2543 Ikeda, Hidetoshi, 5405 Kapaklis-Deliyannis, Georgia Knowles, Donald, 4498 Ho, Bao K., 2550 Ilonen, Jorma, 689 P., 2758 Knust, Birgitt, 3519 Ho, David D., 3579 Im, Dong-Soo, 3095 Kapikian, Albert Z., 4101 Kobayashi, Nobuyuki, 2504 Ho, Monto, 2361 Imbalzano, Anthony N., 3714 Kaplan, Gerardo, 43 Koblet, Hans, 2921 Ho, Rodney J. Y., 2951 Ingemarson, Rolf, 3769 Kaplan, Joshua M., 338 Koch, Gebhard, 3954 Hoffman, J., 1578 Ink, Barbara S., 4632 Karakoz, Ivan, 481 Kodama, Toshiaki, 4709 Hoggan, M. David, 1455 Innes, Cynthia L., 2592 Karlins, Ulrich, 3954 Koehne, Charles F., 1284, Holbrook, Nikki, 1737 Inumaru, S., 3270 Karr, Robert W., 747 2366 Holland, Christie A., 1284 Isfort, Robert J., 2959 Katamine, Shigeru, 1715 Koga, Yasuhiro, 3748 Holland, John J., 2063, 2072, Ishihama, Akira, 5142 Kato, Hideshige, 4298 Kohara, Michinori, 1302, 5354 5030 Ishimoto, Akinori, 4110 Kato, Jun-ya, 683 Koike, Katsuro, 2914, 2936 Holland, Thomas C., 730 Ishizaka, Sally T., 3200 Katoh, lyoko, 2226 Kolakofsky, Daniel, 122, 892, Holley-Guthrie, Elizabeth, Isola, Vicki J., 2325 Katsumata, Tomoko, 1174 1951, 5159, 5166 1729, 3870, 3878 Isom, Harriet, 5293 Kattar-Cooley, Patricia, 696 Kolesnikova, Marina S., 4034 Hollon, Tom, 3353 Ito, Yoshiaki, 1040, 1465, 3669 Katz, David, 1721 Komatsu, Toshihiko, 1302, Holmes, Ian H., 3545 Ivannikova, Tatyana A., 4034 Katz, Richard A., 5319 5354 Holzmann, Heidemarie, 564 Izumi, Kenneth M., 1153, Katze, Michael G., 2244 Kondo, Toshio, 3161 Hom, Richard C., 4157 4455 Katzman, Michael, 5319 Kong, Wing-Pui, 5344 Honda, Ayae, 5142 Kaufman, Randal J., 1651 Koprowski, H., 2885 Honigman, Alik, 2400 Jablonska, Stefania, 4905, Kavlick, Mark F., 1460 Korba, Brent E., 1360, 1612 Honigwachs, Judy, 919 4909, 4910 Kawakami, Toshiaki, 1715, Korolev, Mikhail B., 4034 Honnen, William J., 2674 Jackson, David C., 3087 2343 Koropchak, Celine M., 2392 Hooda-Dhingra, Urvashi, 705, Jackson, Paul, 303, 311 Kawakita, Masao, 182 Kosz-Vnenchak, Magdalena, 714 Jackson, Wallen, 3912 Kawamura, Ikuo, 3748 2893 Hoover, Edward A., 189 Jacob, Francois, 2134 Kawamura, Noriyuki, 1069, Kotler, Moshe, 4325 Hopkins, Nancy, 328, 4210 Jacobson, Connie L., 1756 1302 Kotwal, Girish J., 600 Horak, Ivan D., 2343 Jacobson, Jennie G., 1839 Kawaoka, Yoshihiro, 32%, Koup, Richard A., 584 Horikoshi, Masami, 1869 Jacobson, Steven, 1756 4603 Kovamees, Jan, 1413 Horisberger, Michel A., 2616 Jaenisch, Rudolf, 1049, 4857 Kedinger, C., 5124 Kovesdi, Imre, 3643 Horn, Toby M., 4982 Jahan, Nazma, 2866 Keene, Jack D., 4172 Koyanagi, Yoshio, 4404 Horvat, Rebecca T., 970 Jahn, Gerhard, 1345 Keerikatte, Vijaya, 1924 Kozak, Christine A., 2959, Horwitz, Bruce H., 4515 Jameel, Shahid, 5293 Kelliher, John C., 5046 3678 Horwitz, Marshall S., 5244, James, Michael R., 3837 Kelly, Graham, 4907 Kozak, Susan L., 4958 5455 Jang, Sung K., 1651 Kelly, John J., 383 Kozar, Lee, 2680 Hovanessian, Ara G., 647, Jansen, Robert W., 4932 Kelly, Thomas J., 2798 Kraft, Robert, 3200 2244, 4074 Jansen-Durr, P., 5124 Kelvin, Marjorie, 841 Kramer, Marcus, 4540 Howe, J. Gregory, 1531 Jariwalla, Raxit J., 425 Kemble, George W., 4715 Krasnow, Stephanie, 4097 Howley, Peter M., 3151, 4417, Jeang, Kuan-Teh, 2987, 5501 Kempf, Christoph, 2921 Kraus, Gunter, 5119 5076 Jean-Jean, Olivier, 5451, 5497 Kennedy, Ronald C., 1549 Krauss, Scott, 4603 VOL. 63, 1989 AUTHOR INDEX v

Krieger, Monty, 4767 Lawson, T. Glen, 5013 Logan, John, 532 Martens, Ingrid, 2126 Krohn, Kai, 5046 Lazard, Deborah, 3858 Lomax, Nancy B., 23% Martin, Frank, 2680 Kroner, Philip, 5302 Lazo, Pedro A., 2366 Long, Eric 0., 1756 Martin, G. Steven, 542 Kropinski, Andrew M., 1587 Le, Shu-Yun, 5006 Lopez, Olga, 2270 Martin, Malcolm A., 1455, Krust, Bernard, 647, 4074 Leach, Fredrick S., 1783 Lopez, Susana, 5393 3595, 3784, 4919 Krutzsch, Henry C., 2543 Leake, Robin E., 2388 L6pez-Ferber, M., 1007 Martin, Patrick, 3382 Krystal, Mark, 5142 Leary, Kathryn, 2300 L6pez-Turiso, Jose Angel, Martin, Sandra L., 1839, 2847 Kucera, Paul, 3550 Leblanc, J. F., 2557 5445 Martin, Stephen, 769 Kuge, Shusuke, 1069 Lederman, Muriel, 3180 Lorincz, Attila T., 2829 Martinez, Concepci6n, 5445 Kulka, Michael, 3389 Lee, Han-Jung, 3729 LoSardo, Joseph E., 1087 Martinez, Jesse, 233 Kumar, D. Vinod, 2379 Lee, Hsien-Hsiung, 782 Lother, Heinz, 1827 Martinez-Salas, Encarnaci6n, Kumar, Gyanendra, 5425 Lee, Jung S., 2366 Lowenstine, Linda J., 4277 59 Kunsch, Charles, 2527, 5054 Lee, Tun-Hou, 3579, 4952 Lowenthal, J. W., 1578 Marusyk, Raymond, 689 Kunz, Christian, 564 Legras, Catherine, 513 Lowy, Douglas R., 1384, Marx, Preston A., 4277 Kunzi, Myriam S., 3999 Lehner, Robert, 3792 1404, 1775, 2340, 5469 Masucci, Maria G., 2768, 3135 Kuo, Mark Y.-P., 1428, 1945 Leib, David A., 759, 2893 Lu, Mengji, 3472 Mathews, Christopher K., Kurane, Ichiro, 2486, 5086 Leippe, Donna M., 36 Lu, Yichen, 4115 4736 Kuroda, Kazumichi, 1677 Leis, Jonathan, 5319 Lu, Zhiqiang, 2690 Matsiota, Peggy, 955 Kurth, Reinhard, 5119 Leist, Thomas P., 2813, 4976 Luckow, Verne, 1549 Matsuyama, Toshifumi, 2504 Kuzio, John, 1393 Leitner, Moshe, 3416 Ludlow, John W., 2881 Matthews, James T., 4913 Kwong, Ann D., 4834 Lemon, Stanley M., 4932 Lunsford, R. Dwayne, 2959 Matthews, Tom, 3489 Kyuwa, Shigeru, 3051 Lenches, Edith M., 3459 Luo, Lizhong, 2841 May, Dana L., 3408 Lenoir, G. M., 4121 Lupton, Stephen, 3016 May, Pierre, 3894 Lachmi, Bat-El, 3416 Lenoir, Marie-Cecile, 4317 Lustig, Shlomo, 3416 May-Siroff, Mary, 3080 Lackmann, Martin, 3954 Lenz, Jack, 76, 1087, 3200 Luytjes, Willem, 1408 Mazzara, Gail, 584 Lackner, Andrew A., 4277 Leonard, John, 4919 McAllister, Andres, 1101 Lafay, Florence, 3550 Lequarre, Anne-Sophie, 5194 Mabruk, Mohamed J. E. M. McBride, Alison A., 5076 La Ferla, Frank M., 3852 Lerch, Robert A., 833 F.,4027 McCarthy, Alice M., 18 Lagarias, Donna M., 2099 Leser, Ulrike, 938 Mach, Michael, 1995, 3792 McCrae, Malcolm A., 2048 L'age-Stehr, J., 3525 Levens, David, 1737 Machamer, Carolyn E., 3801 McFarland, Henry F., 1756 Lahijani, Roya S., 233 Lever, Andrew, 4085 Mackow, Erich R., 1661 McGuire, Kathleen, 1604 Lahn, Sharon, 5194 Levin, Judith G., 2405, 2870 Macnab, Joan C. M., 2388 McIntosh, Kenneth, 3541 Lai, Cheng-Jung, 4011 Levine, Arnold J., 739, 790, Mador, Nurith, 2400 McKee, Tom A., 2260 Lai, Chingfeng, 4507 1134, 3016, 4093, 5440 Maduro, L. Joselin, 3466 McKenzie, Sara, 584 Lai, Ching-Juh, 1852, 2486, Levine, Myron, 730 Maeda, Hiroshi, 2252 McKinlay, Mark A., 2002, 2853,5086 Levine, Peter H., 584 Magnuson, J. A., 1525 2476 Lai, Michael M. C., 3693, Levis, Robin, 5216 Magnuson, Nancy S., 1525, McLachlan, Alan, 3919 3729,5285 Levy, Allison, 43 4498 McMahan, Linda, 18 Laimins, Laimonis A., 366, Lewicki, Hanna, 4303 Magnusson, Goran, 2126 Medveczky, Maria M., 1010, 555, 1247 Lewis, James B., 1495, 2348 Magrath, D. I., 1338 3601 Lain, Sonia, 2457 Lewis, John A., 4569 Mahr, Anna, 584 Medveczky, Peter G., 1010, Laithier, Madeleine, 523 Leza, M. Aleida, 3057 Maione, R., 4890 3601 Lamb, Robert A., 28, 1293 Li, Guangpu, 1326 Maizel, Abby, 3190 Meier, Eva, 2072 Lambert, Paul F., 3151 Li, Ji-Su, 4%5 Maizel, Jacob, 5006 Meijer, Ingeborg, 4039 Lambert, Veronique, 4965 Li, Ruoping, 3382 Makino, Masahiko, 1223 Melero, Jose A., 925 La Monica, Nicola, 2357, 3729 Li, Xi-Ling, 3579 Makino, Shinji, 3729, 5285 Mellado, Rafael P., 460 Lampert, Peter W., 2081 Li, Yan, 2841 Maldarelli, Frank, 3784 Meloen, Rob, 1408 Lancz, Gerald, 2534, 4129 Li, Yen, 328, 1800, 4709 Malim, Michael H., 1181, Melucci-Vigo, Gianna, 4979 Lane, David P., 3128 Lichtman-Pleban, 3213, 5006 Mendelson, Ella, 873 Lane, H. C., 4626 Havatzeleth, 4925 Mallet, Francois, 513 Mercadal, Carmen M., 769 Lanford, Robert E., 1549, Lieberman, Paul M., 3040 Malone, Cheryl L., 281 Merchlinsky, Michael, 1595, 4292 Liebowitz, David, 933, 4051, Mama, Saifuddin, 2300 2030, 4354 Langdon, Wallace Y., 3678, 4079 Mandl, Christian W., 564 Meric, Claude, 1558 5420 Liew, Lip-Nyin, 782 Manet, Evelyne, 615, 5276 Merigan, Thomas C., 2951 Lange, Joep M. A., 2118 Lilly, Frank, 3200 Manley, Nancy R., 4210 Merrill, Jean E., 4404 Langlois, Alphonse J., 5046 Limbach, Keith, 3829 Manuelidis, E. E., 1212 Mertz, Janet E., 3884, 4386 Languet, Bernard, 4189 Lin, Joan, 790 Manuelidis, L., 1212 Merville-Louis, M.-P., 3155 Lardenoije, Rend, 3368 Lin, Jung-Chung, 1729, 3870 Mar, Eng-Chun, 1729, 3870, Metsikko, Kalervo, 5111 LaRochelle, William J., 3080 Lin, Ling-Huang, 4011 3878 Mettenleiter, Thomas C., 5475 Larsen, Steen, 9 Linder, Stig, 2126 Maragos, Johnna, 1907 Metzenberg, Stan, 4938 Larson, J. K., 2885 Linial, Maxine L., 5092 Maratos-Flier, Eleftheria, 1318 Meulemans, G., 952 Lashgari, Monir, 463 Linney, Elwood, 2592 Marchetti, Michael E., 2036 Meyer, Heidi, 3792 Lasky, Laurence A., 639 Liou, Ruey-Shyan, 3579 Margolis, Todd P., 4756 Michalides, Rob J. A. M., Laub, Orgad, 919, 1019 Lippe, Roger, 5133 Mariani-Costantini, Renato, 1448, 3466 Laudet, Vincent, 3382 Liu, B., 3026 4982 Michel, Marcel R., 2921 Laughlin, Mark A., 2527 Liu, Qingyun, 5062 Marion, Patricia L., 2445 Midthun, Karen, 4101 Laurent, Anne G., 647, 4074 Ljunggren, Kristina, 3376 Markoff, Lewis, 2853, 3345 Miedema, Frank, 2118 Lauro, Andrea M., 2056 Lo, Szecheng J., 4011 Markovitz, D., 3870 Mikhail, A., 3622 LaVail, Jennifer H., 4756 Lobel, Leslie I., 2629 Marks, Jeffrey R., 790 Milanesi, Gabriele, 4645 Lavine, Joel, 4257 Loeb, Daniel D., 111 Marlor, Christopher W., 85 Milich, David R., 3919 Lawrence, Lisa A., 411 Loeber, Gerhard, 94, 4426 Marschall, Manfred, 938 Miller, Christopher J., 4277 Lawson, Mark A., 3444, 4866 Loewenstein, Paul M., 3516, Marsden, S., 1338 Miller, Douglas, 790 Lawson, Stephen, 425 4962 Marsh, R. F., 1686 Miller, George, 1531, 1721 vi AUTHOR INDEX J. VIROL.

Miller, Lois K., 2008, 4489 Myer, Fred E., 2746 Ohara, Yoshiro, 5492 Pauza, C. David, 3700 Miller, Matthew S., 2002 Myers, Carla, 4445 O'Hare, P., 1641 Pavan, Antonio, 828 Minarovits, Janos, 3135 Myers, Dawn J., 4670 Oh-hori, Nobuhira, 3748 Pavlakis, George N., 1265 Miner, Jeffrey N., 2726 Ohmann, H. Bielefeldt, 1916 Pavlish, O., 4121 Minoo, Parviz, 2718 Nabel, Gary J., 4097 Ohtake, Keiko, 2638 Peak, Meyrick J., 1023 Minor, Philip D., 1338, 4949 Naeve, Clayton W., 4298 Ohtani, Kiyoshi, 3220 Pearson, Lori, 4616 Minson, A. C., 4744 Nagata, Kinya, 3220 Okayama, Akihiko, 4952 Pecorelli, Antonella, 2785 Misra, Ravi, 64 Nagesha, Hadya S., 3545 Okayama, Hiroto, 2374 Peden, Keith W. C., 3362, Mitsuyasu, Ronald, 2585 Naidu, Yathirajulu M., 1800, Okenquist, Sharon A., 76, 5459 4709 3200 Miyoshi, Isao, 4952 Nakagomi, Osamu, 1431 Pedersen, Finn Skou, 5201 Miyoshi, Jun, 1174 Oker-Blom, Christian, 1256 Pedersen, Niels C., 5483 Nakagomi, Toyoko, 1431 Oldstone, Michael B. A., Miyoshi, Yuko, 1174 Nakamura, Gerald, 3489 Peeples, Mark E., 1981 Mizuno, Den'Ichi, 2504 1845, 3330, 4303, 4311 Pei, Rui, 3499 Nakamura, Masataka, 2422, Olivo, Paul D., 196 Mocarski, Edward S., 1435, 3220 Pelaez, Fernando, 5445 1783, 4715 Olmsted, Robert A., 411, 2019 Pelkonen, Jukka, 4409 Nara, Peter L., 5046 O'Neil, Marsha E., 2667 Model, Peter, 3284 Narayan, Opendra, 1811, Pelkonen, Sinikka, 4409 Moelling, Karin, 5489 O'Neill, Edward A., 2798 Pelletier, Jerry, 441 2578, 4682 O'Neill, Raymond R., 1460 Moen, Phillip T., Jr., 3651 Nassal, Michael, 2598 Peluso, Richard W., 3852 Moen, Robert C., 3865 O'Neill, Robert E., 1884, 5069 Pena-Cruz, Victor, 3541 Natarajan, V., 129, 2452 Onions, David E., 1123 Mohr, Ian J., 4181 Natuk, Robert J., 4969 Penaranda, Maria, 2191 Molla, Akhteruzzaman, 2252 Ono, Yasushi, 445 Pefias, Concepci6n, 925 Naujokas, Monica, 5371 Onodera, Kazukiyo, 3748 Mondesert, G., 5124 Neary, Kathryn, 259 Peng, Cheng, 2550 Monell, Craig R., 3250, 3257 Ornelles, David A., 3612 Perbal, Bernard, 1803 Negro, Francesco, 1612 Oroskar, Asha A., 1897 Monick, M. M., 3026 Nehyba, Jiri, 481 Perez-Brefia, Pilar, 925 Monroe, Stephan S., 2191 Oroszlan, Stephen, 1416, 2543 Perkins, Ann, 1 Neill, Suzanne D., 3643 Orth, Gerard, 4905, 4906, Montagnier, Luc, 647, 2270, Neilson, Kathy, 2204 Perkus, Marion E., 3829, 4189 4074, 4464 4909, 4910 Person, Stanley, 730 Nelson, Jay A., 2699, 3330 Ortfn, Juan, 4107, 5445 Montano, Ximena, 3128 Nelson, Nancy J., 196 Pertuiset, B., 2169 Moonen, G., 3155 Ostrow, Ronald S., 4904 Peterhans, E., 2790 Nemeroff, Martin E., 3983 O'Sullivan, M. Aideen, 4027 Moore, D. M., 2143 Nevins, Joseph R., 3643 Peters, G., 1448 Mora, Rene, 366 Otvos, L., Jr., 2885 Petersen, Robert B., 4787, Newcomb, William W., 3777, Ou, Jing-hsiung, 5238 Morahan, Page S., 2300 4697 4986 Morales, D., 952 Ou, Susan, 2680 Petit, Marie-Anne, 1981 Newell, Charles K., 769 Owens, R. J., 978 Morch, Marie-Dominique, Neyt, C., 952 Petrovskis, Erik A., 3240 5153 Nibert, Max L., 4676 Pettersson, Ulf, 2215 Morello, Dominique, 4039 Nicolson, Margery, 2680 Paardekooper, Michel, 3466 Petti, Lisa, 1031 Morgan, A. J., 1967 Niedrig, M., 3525 Pacha, Radiya F., 948 Pettit, Steven C., 5244 Morgan, D. O., 2143 Nigon, Victor, 513 Pacheco, Sariya, 841 Pevear, Daniel C., 2002 Morgan, John, 3190 Nilsson, Stefan V., 2126 Pagano, Joseph S., 1729, Pfaff, E., 798 Morgan, William, 4533 Nishi, Masahiro, 4824 3870, 5505 Pfister, Herbert, 1775 Morin, Nathalie, 2289, 5228 Nishikawa, Kazuo, 4101 Palant, Olga, 216 Phelps, William C., 4417 Morris, David W., 148 Nissen, Mark S., 493 Palese, Peter, 2056, 5142 Philpott, Matthew, 3453 Morrissey, Lloyd C., 4422 Nissim, Ahuva, 1116 Pallas, David C., 4533 Pickup, David J., 1076, 4632 Morse, Herbert C., III, 1223, Nitschko, Hans, 5310 Palmenberg, Ann C., 1054, Pietras, Dennis F., 3983 1489, 2411, 3678, 5420 Noah, M., 798 1822, 5013 Piette, J., 3155 Moscovici, Carlo, 2335 Noda, Tetsuo, 1465 Palomo, Concepci6n, 925 Pinter, Abraham, 2674 Moscovici, M. Giovannella, Noe, Jean S., 3529 Paludan, Kirsten, 5201 Pipas, James M., 3362, 5459 2335 Nomoto, Akio, 1069, 1302, Palumbo, Paul, 4450 Pitta, Anne M., 3801 Moss, Bernard, 226, 411, 600, 5354, 5386 Panet, Amos, 2400, 4325 Pizer, Ellen, 1630 1595, 4224, 4354 Nomoto, Kikuo, 3748 Panganiban, Antonito T., 273 Pizer, Lewis I., 2510 Moss, Eric G., 1884 Nonoyama, Meihan, 2534, Panicali, Dennis, 584 Plachter, Bodo, 1345 Mottet, Genevieve, 892 3315, 4129 Panning, Barbara, 1929 Placzek, M., 1448 Moustakas, Aristidis, 4787 Norkin, Leonard C., 4474 Panthier, Jean-Jacques, 2134 Plagemann, Peter G. W., 4362 Moya, Andres, 2198 Norrby, Erling, 1413 Paoletti, Enzo, 3622, 3829, Plotch, Stephen J., 216 Mueller-Lantzsch, Nikolaus, Notvall, Lena, 1549 4189 Poirier, Yves, 2088 4121, 4609 Nuebling, C. Micha, 4609 Papas, Takis S., 205, 4952, Policastro, Paul F., 4136 Muller, Carolin, 5119 Nunberg, Jack H., 3240 5119 Pollard, A., 1525 Muller, Hermann, 429 Nunes, Wylla M., 3489 Papsidero, Lawrence D., 267 Pollard, Stuart R., 4949 Muller, Mark T., 3737 Nunn, Michael F., 398 Paradiso, Peter R., 349 Polvino-Bodnar, Maryellen, Muller, Martin, 4907, 4911 Nusse, Roel, 3466 Park, Lisa, 1604 4344 Mulligan, Richard C., 4857 Park, Ron E., 1604 Poncet, Didier, 513 Mullins, James I., 189, 2108 Obalek, Slavomir, 4905, 4909, Parker, Diana, 2959 Ponta, Helmut, 4540 Munger, Karl, 4417 4910 Parks, Griffith D., 1054 Pontisso, Patrizia, 1981 Munholland, Janet M., 383 O'Callaghan, Dennis J., 1275, Parris, Deborah S., 137, 5023 Ponzetto, Antonio, 1612 Munn, Robert J., 148 5101 Parrott, Carmen, 4919 Popper, Hans, 1360 Murdin, Andrew D., 5251 O'Connell, Mary A., 4210 Parsons, J. Thomas, 291 Popple, S., 3622 Murphy, Brian R., 411 O'Conner, Robert, 4590 Parsons, Ramon, 94 Portner, A., 2233 Murphy, John E., 319, 2629 O'Donnell, Paul V., 1284, Parvin, Jeffrey D., 5142 Poss, Mary L., 189 Murthy, Shridhara C. S., 3307 2366 Patel, Dhavalkumar D., 1076 Post, Leonard E., 3240 Murti, G., 2233 Offit, Paul A., 3279, 3507 Patel, Nita U., 5293 Posthumus, Willem, 1408 Muster, Thomas, 2056 Offord, Elizabeth A., 2388 Paterson, Reay G., 1293 Poteat, Harry T., 1604 Muttini, Marco, 4645 Ogawa, Koji, 4110 Paul, Ralph, 4958 Potter, Terry A., 2623 Muzyczka, Nicholas, 3095 Ogura, Hisashi, 3555 Pauli, G., 3525 Powers, James C., 2056 VOL. 63, 1989 AUTHOR INDEX vii

Pozzi, L., 4890 Rhode, Solon L., III, 349, Ruben, Steven, 1, 4438 Schlesinger, Sondra, 5310 Prehaud, Christophe, 3550 4249 Rubinstein, Sheryl J., 4689 Schlicht, Hans-Jurgen, 2995, Presley, John F., 1975 Ricciardi, Robert P., 1514 Rudolph, Stefanie-Anja, 1345 5399 Preston, Chris M., 2260, 3513 Rice, Charles M., 1194, 1326, Rueckert, Roland R., 36, 2476 Schloemer, Robert H., 3065 Prives, C., 912 3459, 5216 Ruegg, Curtis L., 3250, 3257 Schmidt, Brian J., 2829 Prokoph, Helmuth, 1441 Rice, Nancy R., 5194 Ruiz-Linares, Andres, 4199 Schmidt, Marion, 429 Pronk, Gijsbertus J., 1470 Rice, Stephen A., 3399 Ruley, H. Earl, 3227 Schmidt, Michael F. G., 429 Psallidopoulos, M. C., 4626 Richards, Douglas, 5302 Ruprecht, Ruth M., 1049 Schneider, Achim, 4911 Puddu, Patrizia, 2785 Richter, Joel D., 4047 Ruscetti, Francis W., 267 Schnittman, S. M., 4626 Pugh, John, 1371 Rickinson, Alan B., 1031, Rush, Mark G., 64 Schoen, Frederick J., 4840 Purcell, Richard, 1 1967 Russel, Marjorie, 3284 Schuermann, M., 1448 Purcell, Robert H., 1360, 5364 Riddle, Lavon, 3489 Russell, Darcy L., 1619 Schuetze, Scott, 4958 Pusztai, Rozalia, 3516 Riechmann, Jose Luis, 2457 Rutter, William J., 579 Schultz, Alan M., 2370, 2959 Puvion-Dutilleul, F., 2169 Riggio, Marcello P., 1123 Ruusala, Aino, 5328 Schultz, Joseph A., 2680 Pyle, Stephen W., 5046 Righthand, V. Fay, 5268 Ryan, J. Michael, 2260 Schulze, Thomas, 5489 Ryan, J. P., 250 Quatannens, Brigitte, 3382 Rimsky, L., 1578 Schwartz, Charles D., 1704 Rinaldo, Charles, 2361 Rynditch, Alla V., 481 Schwarz, Claudia, 2820 Quinn, Allison P., 2829 Ryu, Wang-Shick, 4386 Quinn, John P., 1737 Rindi, Guido, 4645 Schwedes, John F., 4426 Rinke, Yvonne, 3926 Schwyzer, Martin, 4882 Rabert, Douglas K., 5334 Rishell, William, 2680 Sacher, Robert, 4545 Scott, Fredric W., 436 Rabson, Arnold B., 4919 Risser, Rex, 1989, 4670 Sadzot-Delvaux, C., 3155 Scott, Robert E., 2718 Racaniello, Vincent R., 43, Risuleo, Gianfranco, 4979 Safer, Brian, 2244, 3423 Scullion, F., 1967 1884, 2357, 5069 Riviere, Yves, 2270, 4464 Saif, Linda, 2191 Sedarati, Farhad, 1153, 3844, Race, Richard E., 9, 175 Rixon, Frazer J., 137 Sajjadi, Fereydoun G., 356 4455 Racevskis, Janis, 456 Robbins, A. K., 250, 4055 Sakai, Norio, 1174 Sedman, Sylvia A., 3884 Radke, Kathryn, 2099 Robbins, Keith C., 1715, 2343 Sakai, Yuko, 3661 Seeger, Christoph, 1907, 4665 Radonovich, Michael, 2987 Roberts, Thomas M., 4533 Salas, Margarita, 460 Seiberg, Miri, 1134, 4093 Ragnar, Eva, 3135 Robey, W. Gerard, 5046 Salfeld, J., 798 Seibl, Rudolf, 938 Ragot, Thierry, 3109 Robinson, William S., 2445, Salhi, Samia, 5497 Seigneurin, J. M., 4121 Rahmsdorf, Hans J., 4540 2857 Salmi, Aimo, 689 Seiki, Motoharu, 3185 Rajan, T. V., 2623 Robson, Lori, 669 Salome, Nathalie, 4797 Sekaly, Rafick P., 1756 Raju, Latha, 5159 Rodriguez, Jose F., 997 Salonen, Reijo, 689 Sekigawa, Iwao, 4370 Raju, Ramaswamy, 122, 5159, Rodriguez, Moses, 4242 Salvato, Maria, 1845, 4303 Sekulovich, Rose E., 4590 5166, 5216 Rodrfguez-Cerezo, Emilio, Salzberg, Samuel, 1116 Sellins, Karen S., 572 Rall, Glenn F., 2690 2198 Salzman, Norman P., 129, Semler, Bert L., 847, 3444, Ramig, Robert F., 4525 Roeder, Robert G., 1869, 3761 2452, 4626 4866, 5344, 5492 Randall, R. E., 1808 Rogler, C. E., 2638 Samarut, Jacques, 513 Semon, Kenneth M., 2680 Raney, Anneke K., 3919 Roizman, Bernard, 1059 Sample, Jeffery, 933, 4079 Sendele, Deborah, 769 Ransone, Lynn J., 4563 Rommelaere, Jean, 4797 Samuel, Kenneth P., 4952 Senkowski, Andrea, 4469 Rapin, N., 1916 Roome, Aaron, 3190 Samulski, Richard Jude, 3822 Sergeant, Alain, 607, 615, Rapp, Ulf R., 1489, 2411 Rooney, Cliona M., 1531, Sanders, Tatia C., 4459 5276 Rappaport, Jay, 463 1721, 3109 Sandler, Abby B., 624 Setzer, Paulette Y., 4756 Raptis, Leda, 753 Roos, Raymond P., 4469, Sandri-Goldin, Rozanne M., Sexton, Connie J., 5505 Ratka, Michael, 3954 5344,5492 4590, 4976 Shaffer, Daniel J., 4431 Ratner, Lee, 3205 Rose, John K., 3569, 3801, Sangwan, Indu, 1959 Shafferman, Avigdor, 3416 Raviprakash, Kanakatte S., 5328 Sansonetti, Philippe, 2270 Shan, Bei, 4569 5455 Rosen, Craig A., 1, 2857, 4438 Santos, Rene E., 3435 Sharma, Opendra K., 948 Rawlins, Dan R., 101 Rosen, J., 3525 Sarasin, Alain, 3837, 4520 Sharma, Surendra, 3190 Rawls, J. Alan, 4962 Rosenberg, Martin, 1569 Sarngadharan, M. G., 1416 Sharmeen, Lamia, 1428 Raychaudhuri, Pradip, 3643 Rosenblatt, Joseph D., 1474, Sarnow, Peter, 467 Sharp, Phillip A., 4210 Razzaque, Abdur, 425, 2866 4875 Saron, Marie-Francoise, 955 Sharpe, Arlene H., 1049 Read, G. Sullivan, 1897 Rosenblum, Betsy, 5364 Sasai, Hitoshi, 1174 Shatkin, Aaron J., 2415 Redemann, Brunhild E., 873 Rosenthal, Alexander, 2081 Satake, Masanobu, 1040, 3669 Shaughnessy, Margaret A., Reeves, Raymond, 1525, 4498 Rosenthal, Leonard J., 425, Sato, Hiroshi, 3555 1293 Register, R. Bruce, 5037 2866 Sato, Masahiro, 683 Shaul, Yosef, 919 Regnault, Armelle, 2270 Ross, Elizabeth K., 3595, Saule, Simon, 3382 Shaver, M. Kathy, 4904 Regnier, Daniel C., 3678 4919 Savatier, Pierre, 513 Shaw, Andrey, 5328 Reha-Krantz, Linda J., 4762 Rossignol, Jean-Michel, 5451, Sawai, Earl T., 3961 Sheahan, Brian J., 4027 Reichel, Ronald, 3643 5497 Scangos, George A., 1891 Sheffer, D., 1811 Reilly, Linda, 3323 Rossmann, Michael G., 2002, Schaefer, Timothy S., 2870 Sheldrick, P., 2169 Rein, Alan, 2370, 2405, 2870 2476 Schaffer, Priscilla A., 18, 759, Shenk, Thomas, 3479, 3612, Reinacher, Manfred, 1695 Rothman, Alan L., 2486 1861, 2036, 2893, 4579 3822 Reiss, Carol S., 3541 Rott, Rudolf, 429, 1677, 1695 Schaller, Heinz, 798, 2598, Shepard, Alyssa A., 1203, Reitz, Marvin S., 2374 Rouse, Barry T., 769 2995, 5399 3714 Rekosh, David, 1959 Rousselet, G., 4121 Schellekens, Peter T. A., 2118 Shepard, Deborah A., 2476 Rentier, B., 3155 Routbort, Mark, 4469 Schild, G. C., 1338 Sherman, Diane, 4264 Repaske, Roy, 1455, 1460 Roux, Laurent, 892 Schiller, John T., 1404, 1775, Sherman, Levana, 4925 Resnick, James, 2497 Rowe, David T., 3109 2340, 3151 Sherry, Barbara, 4840, 4850 Resnick-Roguel, Nitzan, 4325 Rowe, Martin, 1031 Schirmbeck, Reinhold, 2308 Sheu, Michael, 267 Rey, Marie-Anne, 647, 4074 Rowe, Mary E., 2108 Schlegel, Richard, 4417 Shi, Yang, 3479 Reynolds, Pamela L., 4285 Roy, P., 3270 Schlehofer, Jorg R., 2152 Shibata, Riri, 4110 Rhee, Eunjoo, 432 Roy-Burman, Pradip, 2379, Schlesinger, R. Walter, 1695, Shibuta, Hiroshi, 3661 Rhode, Brett W., 3209 4234 1704 Shieh, Chien-Kou, 3693, 3729 viii AUTHOR INDEX J. VIROL.

Shih, Andy, 64 Steimer, Kathelyn S., 1451, Tack, Lois C., 1310, 2352, Tiollais, Pierre, 4395 Shiraishi, Hiroyuki, 2422 3176 3362 Tishon, Antoinette, 4303 Shiraishi, Koichi, 3555 Stein, Barry S., 1451 Tada, Hiroomi, 463 Toita, Masami, 3234 Short, Mary K., 1087 Stein, Bernd, 4540 Tada, Tomio, 3185 Tolskaya, Elena A., 4034 Shubin, Richard A., 3051 Stein, Steven, 4469, 5492 Taffs, F., 1338 Tomassini, Joanne E., 36 Shull, Bruce C., 3180 Steinberg, Bettie M., 957 Tago, Katsuhiko, 1302, 5354 Topham, David J., 4242 Sia, Rey, 1 Steinberg, Sharon P., 4264 Taguchi, Fumiaki, 3195 Torrisi, Maria Rosaria, 828 Siddiqui, Aleem, 5293 Steinhauer, David A., 2063, Taichman, Lorne B., 957 Tracy, Steven M., 4148 Siebert, Gary R., 2325 2072, 5030 Takada, Kenzo, 445 Traktman, Paula, 841, 3999 Siegel, Michael L., 2335 Steinman, Richard A., 1514 Takahashi, Hirohiko, 3161 Traugh, Jolinda A., 3912 Siekevitz, M., 1578 Stenberg, Richard M., 1232, Takahashi, Kazuo, 3161 Traynor, Patricia, 5302 Silver, Jonathan, 1924 2699 Takahashi, Michiaki, 3161 Treasurywala, Adi M., 2002 Silverman, Lauren, 4376 Stenlund, Arne, 1743 Takeshita, Toshikazu, 2422 Tregear, Geoffrey W., 3087 Silverstein, Saul, 3513 Stenzel, Molly, 4115 Taketo, Makoto, 2317, 4431 Tremblay, Michel L., 987 Simon, Gwynn, 4019 Stephens, Robert M., 5194 Takeya, Tatsuo, 683 Trdpo, Christian, 4965 Simon, M. Celeste, 3643 Steven, Alasdair C., 3777 Takimoto, Masato, 1737 Trescol-Biemont, Sisman, J., 2169 Stevens, Jack G., 1153, 3844, Takimoto, Toru, 3555 Marie-Claude, 5276 Sisson, Brad, 2959 4455, 4976 Tambourin, Pierre E., 1384, Trimble, John J., 3307 Skalka, Anna Marie, 5319 Stevens, John T., 4913 3944 Tronick, Steven R., 2877, Skehel, Paul, 3489 Stewart, R. Gregory, 2680 Tan, Tse-Hua, 3761 4925 Skinner, M. A., 1338 Stewart, Sandra, 1393 Tanaka, Akiko, 2534, 3315, Tse, Anthony, 1265 Sklaviadis, T. K., 1212 Stillman, Bruce, 4181 4129 Tsichlis, Philip N., 2366 Slaoui, M., 952 Stinski, Mark F., 281, 3026, Tanaka, Atsushi, 1465 Tsui, Shanli, 5175 Slavicek, James M., 4047 3330 Tanaka, Junji, 3555 Tsuruoka, Hiroshi, 5464 Small, Judy A., 1891, 3001 Stockdale, Anne M., 659 Tanaka, Saichiro, 3555 Tu, Chialing, 3983 Smiley, James R., 1929 Stoddart, Cheryl A., 436 Tang, Wei-Jen, 242, 5478 Tugwood, Jonathan D., 983 Smith, Carolyn L., 1569 Stohlman, Stephen A., 3051 Tang, Xi-Lin, 3087 Tupper, Joan, 4945 Smith, Colton A., 2036 Stollar, Victor, 992 Tangy, Frederic, 1101 Turner, Willie, 4919 Smith, Cynthia C., 3389 Stoltzfus, C. Martin, 1669 Taniguchi, Koki, 4101 Tursz, T., 4121 Smith, Lisa L., 5013 Stott, E. James, 833 Tanneau-Salvadori, Francoise, Twu, Jr-Shin, 2857, 3065 Smith, Marilyn, 3878 Stout, Ernest R., 3180 2270 Tyler, Kenneth L., 759 Smith, Randall F., 450 Stoye, Jonathan P., 1763, 3810 Tatem, Joanne, 992 Tzen, Chin-Yuan, 2718 Smith, Temple F., 450 Strand, Mette, 3250, 3257 Tattersall, Peter, 1002, 3902 Strauss, Ellen G., 1194, 3142, Ueckermann, Christian, 3954 Smith, Thomas J., 2476 Tavis, John E., 901 Ullrich, Stephen, 3894 Smith-White, Brian, 2959 3459 Taylor, Benjamin A., 1763, Strauss, James H., 1194, 3142, Umene, Kenichi, 1877 Smotkin, David, 1441 3810 Urasawa, Shozo, 4101 Smyth, Joan M. B., 4027 3459, 4653 Taylor, Howard P., 3991 Strebel, Klaus, 1455, 3784 Urasawa, Tomoko, 4101 Sodora, Donald L., 5184 Taylor, John, 1428, 1945, 4292 Urzainqui, Ana, 4729 Sodroski, Joseph G., 1604, Streilein, J. Wayne, 4808 Taylor, Naomi, 1721 Stuhlmann, Heidi, 4857 Uttenthal, Aase, 9 4085, 4115 Tedder, Davol G., 2510 Utz, U., 1995 Soe, Lisa H., 3693 Sturzbecher, Horst W., 3894 Tegtmeier, Gary E., 4064 Solem, Suzanne M., 2392 Su, Lishan, 3399 Tegtmeyer, Peter, 94, 1310, Vaillancourt, Peter, 1743 Soloway, Paul D., 3612 Su, Tsung-Sheng, 4011 4426, 5175 Vakharia, V., 2143 Soma, Gen-Ichiro, 2504 Subramani, Suresh, 356 Temin, Howard M., 3209 Valcarcel, Juan, 4107, 5445 Soman, Gopalan, 4157 Subramanian, Subhalakshmi, Temple, Gary F., 2829 Valentine, Janette M., 809 Sonenberg, Nahum, 441 3423 Tennant, Bud C., 1360, 4665 van Dam, Hans, 1470 Sonigo, Pierre, 4395 Suda, Yoko, 3185 Tenser, Richard B., 2861 van der Eb, Alex J., 1470, Sonoda, Shunro, 3161 Sugamura, Kazuo, 2422, 3220 Tershak, Daniel R., 4441 3368, 4039 Soret, Johann, 1803 Sugden, Bill, 2469, 2644 Tersmette, Matthijs, 2118 van der Voort, Lucia H. M., Soultanakis, Emmanuel, 4616 Sugg, Nancy, 3323, 5475 Tevethia, Mary J., 4426 1485 Soussi, Thierry, 3894 Sugimoto, Chie, 3195 Thach, Robert E., 5013 Vandevelde, M., 2790 Southern, Peter J., 1938 Sugimura, Haruhiko, 5405 The, T. Hauw, 1485 van Drunen Littel-van den Souyri, M., 3944 Sugita, Kenji, 1715 Thelander, Lars, 3769 Hurk, Sylvia, 2159 Souza, Larry, 2680 Sullivan, John L., 584, 1010 Theodore, Theodore S., 3595 Van Dyke, Terry, 2204 Sowder, Raymond C., 2543 Summers, Jesse, 1371 Theunissen, Henri J. M., 3466 van Hille, Benoit, 4797 Spaan, Willy, 1408 Summers, Max D., 1256, 1549 Thiem, Suzanne M., 2008, Vannier, David M., 3693 Spear, Patricia G., 52, 819, Summers, William C., 5062 4489 Varmus, Harold E., 338 3435 Sun, Cecily R. Y., 3579 Thierry, Franqoise, 4317 Varsanyi, Tamas M., 1413 Speck, Samuel H., 1531 Sun, Nai-Chau, 3579 Thimmappaya, Bayar, 3423 Vass, William C., 1384, 5469 Spector, Deborah H., 3117, Sung, Juei-Low, 4165 Thomas, Christopher Y., 1284 Vasudevachari, M. B., 129, 5334 Sureau, Camille, 4292 Thomas, Jean-Luc, 513 2452 Spehner, Daniele, 1814 Sussman, Mark A., 3051 Thompson, Carol L., 705, Vaughan, Patrick J., 4590 Spiro, Craig, 4434 Sutjipto, Suganto, 4277 714, 948 Velan, Baruch, 3416 Sportza, L., 2557 Suzuki, Yasuo, 4298 Thompson, L. M., III, 4626 Velu, Thierry J., 1384, 5469 Springett, Gregory M., 3865 Svoboda, Jan, 481, 1015 Thoraval, Pierrick, 513 Verderame, Michael F., 338 Srinivasan, Ashok, 3362, 5459 Swain, Amanda, 3301 Tibbetts, Clark, 1833 Verdier, Gerard, 513 Sriram, Subramaniam, 4242 Swanstrom, Ronald, 111 Ticehurst, John, 5364 Verdin, Eric M., 1318 Srivastava, Arun, 3034 Sweidler, Alfred, 1371 Tierney, Eveline Lee, 375, Veronese, Fulvia di Marzo, St. Jeor, Stephen C., 233 Szafranski, Przemyslaw, 5153 3755 1416 Stacy, Terryl, 5208 Szomolanyi, Eva, 3601 Tilley, Shermaine A., 2674 Vesole, David H., 3330 Stallard, Virginia, 2108 Szurek, Paul F., 471 Timmers, H. T. Marc, 1470 Veyrunes, J. C., 1007 Stary, Anne, 3837 Ting, Robert C. Y., 1400, Vidal, Silvia, 892, 1951 Stehelin, Dominique, 3382 Tachibana, Nobuyoshi, 4952 3579 Vigon, I., 3944 VOL. 63, 1989 AUTHOR INDEX ix

Vlasak, Reinhard, 2056 Welch, Siao-Kun Wan, 3974 Wollmann, Robert, 4469 Ye, Zhiping, 3586 Vlodavsky, Israel, 4325 Weller, Sandra K., 591 Wong, A., 2557 Yeh, Chau-ting, 5238 Voelkerding, Karl, 2289 Wells, Frances V., 1360 Wong, Timothy C., 1162, Yen, T. S. Benedict, 5238 Volsky, David, 4438 Welsh, Raymond M., 4969 2977, 5464 Yetter, Robert A., 1223 von Melchner, Harald, 3227 Wen, Leying, 2191 Wood, Charles, 970, 4064 Yeyt, C., 952 von Ruden, Thomas, 677 Wen, Long-Thung, 3315 Woodward, Suann, 2874 Yin, Fay H., 2396 Vousden, Karen H., 2340, Wengler, Gerd, 2521 Woodworth, C. D., 159 Yogo, Yoshiaki, 3195 2650 Wengler, Gisela, 2521 Wooley, Dawn P., 4709 Yokomori, Kyoko, 3729 Vugler, Leone G., 403, 1995 Wenske, Elizabeth, 4840 Workman, Jerry L., 1869 Yolken, Robert H., 2191 Vydelingum, Soopayah, 689 Werner, Albrecht, 5119 Wright, Cynthia F., 4224 Yoshida, Mitsuaki, 3185, 3234 Werstuck, Geoff, 5509 Wright, Deann K., 3240 Yoshiike, Kunito, 965 Wachsman, William, 1474 Wertz, Gail W., 833, 4767 Wright, Dowain A., 3117 Yoshikawa, Yasuhiro, 5464 Wade, John D., 3087 Westrop, G. D., 1338 Wright, Jocelyn H., 1310, Yoshimura, Fayth K., 3353, Wagner, Edward K., 3844, Wettstein, Felix O., 1441 2352,3362 4945 4455 Weyer, Ulrike, 3535 Wright, Rebecca, 5310 Yoshinaka, Yoshiyuki, 2226 Wagner, Robert R., 2841, Whealy, M. E., 250, 4055 Wu, Foon, 2585 Young, D. F., 1808 3586 Whitaker, C., 3622 Wu, S.-S., 2233 Young, Lawrence S., 983, Wahlberg, Johanna M., 4991 White, David O., 2758, 3087 WuDunn, Darrell, 52 1031, 1967 Wahren, B., 3525 White, Jacquelynn S., 4498 Wunner, W. H., 2885 Yu, Xiu-ping, 809 Wakasugi, H., 4121 Whitford, Marc, 1393 Wyatt, Carol R., 4498 Yuan, C. C., 205 Walker, Duard L., 901, 2180 Whitt, Michael A., 3569 Wymer, James P., 2773, 3389 Yuen, P. H., 471 Walker, Thomas A., 3408 Whitton, J. Lindsay, 1845, Wysokenski, Doreen A., 2657 Walser, Anton, 3926 4303, 4311 Xanthoudakis, S., 2557 Zachow, Karen R., 4904 Walton, Tracy H., 3651 Wiest, David L., 659 Zaghouani, Habib, 2674 Wang, Fred, 4079 Wigdahl, Brian, 2527, 5054 Yaegashi, Nobuo, 2422 Zagouras, Panayiotis, 5328 Wang, Hwa-Chain R., 291 Wilcox, Kent W., 6%, 2510 Yager, Dorne R., 759 Zamb, Tim, 2159 Wang, Yeong, 4736 Wilcox, Wesley C., 2325 Yaginuma, Katsuyuki, 2914 Zantema, Alt, 3368 Wano, Y., 1578 Wildeman, Alan G., 383 Yajima, Akira, 2422 Zeller, Helmut, 2616 Ward, David C., 4344, 5425 Will, Hans, 5451 Yajima, Hajime, 1465 Zempsky, William, 4344 Wareham, K. A., 1338 Willey, Ronald L., 1455, 3595 Yakobson, Bracha, 1023 Zentilin, Lorena, 4645 Warren, Noreen, 2644 Williams, Mark A., 28 Yalamanchili, V. Ramana R., Zhang, Jiayou, 1107 Watanabe, Naoko, 4824 Williamson, Judy L., 1686 1275 Zhang, Yi-Ming, 2486 Watanabe, Sumie, 965 Wills, John W., 4331 Yamada, Masahito, 2081 Zhao, Bangti, 2853 Waters, David J., 5046 Wilson, Barbara A., 3408 Yamaguchi, Yuko, 1040, 3669 Zhou, Wei W., 2835 Watts, Norman R. M., 2427 Wilson, Carolyn, 2374 Yamamoto, Naoki, 2504 Zhu, Jiyue, 4777 Webster, Robert G., 32%, Wilson, Michael C., 4136 Yamanishi, Koichi, 3161 Zhu, Xiuxuan, 3513 4298, 4603 Wilton, Sharon, 1540 Yamanouchi, Kazuya, 5464 Zink, M. Christine, 2578 Weichselbraun, Irene, 961 Wimmer, Eckard, 1651, 5251 Yang, Den-Mei, 2746 Zinkernagel, R. M., 2813 Weigelt, W., 3525 Windheuser, Michael G., 4064 Yang, Shiaolan, 3209 Zolla-Pazner, Susan, 2674 Weimer, Thomas, 5451 Wingett, Denise, 4498 Yang, Wen K., 2746 Zompetta, Claudia, 828 Weinberg, A. D., 1525 Winocour, Ernest, 1023 Yaniv, Abraham, 2877, 4925 Zsak, Laszlo, 3323, 5475 Weinmann, Roberto, 3858 Wintersberger, Erhard, 961 Yaniv, Moshe, 2567, 4317 Zuckermann, Federico, 3323 Weinstat, Debra L., 4515 Wirth, Urs V., 4882 Yao, Feng, 3338 Zurbriggen, Andreas, 1505, Weinstein, Yacob, 2959 Wisniewski, Rebecca, 3209 Yates, John L., 2657 2081 Weiss, Barbara, 5310 Witter, Richard L., 504 Yatsula, Bogdan A., 481 zur Hausen, Harald, 2152, Weitsman, Stacy, 4875 Wolf, Hans, 938 Yauk, Yar-Khing, 4011 3683 SUBJECT INDEX VOLUME 63

Abelson murine leukemia virus LI proteins Antigen-presenting liposomes helper virus requirements virion assembly, 3612 herpes simplex virus pre-B- and T-cell lymphomas, 2088 virus-associated RNAs treatment, 2951 tumor induction, 1989 temperature-dependent expression, Anti-idiotypic antibodies Actin cytoskeleton 5445 influenza A virus matrix protein adenovirus-infected rat cells Adenovirus type 12 ribonucleoprotein-binding sites, 3586 cell cycle, 311 ElA-mediated repression influenza virus EIA gene, 311 major histocompatibility complex class immune response, 2758 Adeno-associated virus I, 4039 Aphidicolin-resistant mutants p5 and p19 promoter expression virus-associated and LI RNAs herpes simplex virus type 1 negative trans regulation by rep pro- replication defect in hamster cells, DNA polymerase substrate specificity, tein, 4450 3535 2874 P5 promoter, 3479 Adenovirus types 2 and 5 vaccinia virus DNA polymerase gene, recombinant helper-free stocks, 3822 EIA trans-activating peptides 4060 Rep protein synthesis, 873 mutational analysis, 3516 Arachidonic acid terminal repeat binding, 3095 EIA, myc, and ras oncogenes Rous sarcoma virus-transformed cells type 2 DNA-binding nuclear proteins, cytolytic susceptibility, 3408 metabolism modulation, 2929 3034 precursor to the terminal protein AS virus UV-irradiated cells mutations, 5244 BK virus variant replication, 1023 Adenoviruses nucleotide sequence, 901 Adenovirus type 1 actin cytoskeleton Autographa californica nuclear polyhedro- unusual E3 region, 5455 cell cycle, 311 sis virus Adenovirus type 2 EIA gene, 311 CG30 gene ancillary leaders and fiber translation cellular transcription factor E2f zinc finger and leucine zipper, 4489 monkey cells, 4376 E2A gene expression, 2709 envelope glycoprotein gp67, 1393 DNA interaction with nuclear matrix, EIA protein shifts major capsid protein gene, 2008 4344 Ser-89 phosphorylation, 1569 transcriptional regulatory region Ela 289R protein E2A deletion mutant early promoter elements, 493 transactivating domain, 1495 DNA-binding protein, 2289 Avian erythroblastosis virus Ela proteins nuclear transport, 2289 novel mast cell-basophil precursor target temperature-sensitive transactivation, early EIA proteins transformation in Japanese quail, 2335 2348 actin reorganization, 303 Avian hemangioma-inducing retrovirus ElA-responsive promoter elements, 3499 cell cycle alteration, 303 envelope glycoprotein early region 4 gene activation in rat cells, 303 cytocidal effect, 4325 nuclear RNA stability, 624 expression vectors Avian influenza viruses gene reactivation human immunodeficiency virus type 1, H5 hemagglutinin 5-azacytidine, 3519 129 pathogenicity, 3453 EIA trans activation, 3519 inverted terminal repeat sequences, 5133 Avian leukemia virus E26 major late promoter attenuated RNA JE gene transcription v-ets function DBP interaction, 1134 EIA repression, 1470 murine retroviral recombinant, 205 minute virus of mice-host nucleoli inter- major late promoter Avian leukosis virus actions, 3651 attenuation in monkey cells, 4093 Rous-associated virus type 1 Adenovirus type 3 downstream element, 5124 retrovirus replication, 3301 EIA promoters oncogenicity of transformed cells RNA polyadenylation, 3301 autoregulatory responses, 1833 heat shock protein hsp27, 3368 vector-packaging cell line, 513 Adenovirus type 5 poly(A) site selection mechanisms, 532 Avian leukosis virus RAV-1 DNA-binding protein mutations virus-associated RNA I c-myb and avian B-cell lymphomas, 1630 phosphorylation, 5228 functional dissection, 3423 Avian myeloblastosis virus synthesis, 5228 Adult diarrhea rotavirus retrovirus protease EIA gene product structural proteins, 2191 dimeric aspartic proteinase, 2226 nuclear localization, 4047 Akv virus Avian retrovirus E26 Xenopus oocytes, 4047 long terminal repeat ets sequence EIA promoters T-lymphoma cell-specific element, 76 erythroblastosis in chickens, 398 autoregulatory responses, 1833 long terminal repeats Avian retrovirus FH3 EIA proteins relative expression, 5201 v-myc proto-oncogene, 5092 phosphorylation at Ser-89, 987 LTR enhancer regions Avian retroviruses Elb 58-kDa protein-p53 complex forma- interactions, 3353 integration protein cleavage tion, 1792 nuclear proteins in vivo integration sites, 5319 E4 expression differential DNA binding, 4945 lymphoproliferative disease virus of tur- cyclic AMP and EIA induction, 3057 Aleutian mink disease virus keys, 2877 E4 gene passive antibody transfer Avian sarcoma virus PR2257 E2F activation, 3643 pneumonia, 9 c-src transduction, 481 E4 gene products replication, 9 Avian sarcoma-leukosis virus lytic infection effects, 2605 Antibody-dependent cell-mediated cytotox- integration protein cleavage early ElA proteins icity in vivo integration sites, 5319 actin reorganization, 303 human immunodeficiency virus 5-Azacytidine cell cycle alteration, 303 antigenic specificity, 584 adenovirus-transformed cells gene activation in rat cells, 303 Human immunodeficiency virus types 1 reactivation, 3519 early region 4 and 2 and SIVMAC isolates Epstein-Barr virus expression late gene expression, 631 type- and strain-specific antigens, 3376 nuclear antigen and latent membrane

x VOL. 63, 1989 SUBJECT INDEX xi

protein, 3135 nant, 3270 Cardioviruses Azidothymidine Bovine herpesvirus 1 mengovirus RNA transcripts human immunodeficiency virus type 1 glycoproteins gI and gIll cloning and synthesis, 1822 cell-to-cell transmission, 2361 vaccinia virus recombinant, 2159 poly(C) tracts, 1822 neutralizing antibody, 2361 neutrophil-derived antiviral protein, 1916 c-cbl proto-oncogene T-cell proliferation, 1525 expression in thymus and testis tissue, B19 virus transcription map, 4882 5420 erythroid lineage cells Bovine leukemia virus c-fos proto-oncogene propagation, 2422 activation in blood cells, 2099 human T-cell leukemia virus type I GC-box motif persistent infection of rabbits, 4498 p40't, 3220 transcription control, 4814 retrovirus protease c-fpslfes proto-oncogene Bacteriophages dimeric aspartic proteinase, 2226 Friend murine leukemia virus choleraphage 4)149 replication Bovine papillomavirus retroviral vector, 5469 V. cholerae biotype el tor, 392 E2 protein transforming activity, 5469 endosialidases trans activation in S. cerevisiae, 4422 Chicken embryo fibroblasts cleavage specificity, 4409 multiple E2 gene products partially activated p60c-src, 683 filamentous bacteriophage packaging sig- genetic assignment, 3151 Chicken neuroretina cells nal, 3284 Bovine papillomavirus type 1 Pl35gag-myb-e's and p61/63mYc nuclear 4)29 DNA El mutants oncogenes protein p6 promoters, 460 transforming activity, 1775 transformation, 3382 transcription in vitro, 460 E2 phosphorylation sites, 5076 c-myb locus 4)149 replication E5 peptide domains avian leukosis virus RAV-1 V. cholerae biotype el tor, 392 cellular DNA synthesis, 4962 B-cell lymphomas, 1630 PK1A to PK1E E5 protein transforming protein, 4515 insertional mutagenesis, 1630 endosialidase cleavage specificity, E6 gene Coronaviruses 4409 mutational analysis, 2340 defective interfering RNA Pseudomonas aeruginosa phage 4)PLS27 early and late polyadenylation sites high-frequency leader sequence DNA characterization, 1587 transcriptional termination, 3529 switching, 5285 T4 immunity gene, 3472 growth-arrested transformed cells feline infectious peritonitis T4 td and frd deletions, 4736 DNA amplification, 2215 feline macrophage resistance, 436 T4 tsL56 DNA polymerase mutations, new cDNAs, 1743 virulence, 436 4762 ORFs E6 and E7 mouse hepatitis virus gene 2b T4 wedges and rings mouse C127 cell transformation, 259 RNA transcription regulation, 3729 cross-linking, 2427 Bovine parainfluenza virus mouse hepatitis virus gene A Baculovirus recombinants envelope protein genes autoprotease activity, 3693 bluetongue virus type 10 NS3 proteins, recombinant vaccinia viruses, 3661 murine conserved epitope, 1408 3270 syncytium formation, 3661 Cottontail rabbit herpesvirus rhesus rotavirus outer capsid protein Bovine respiratory syncytial virus genome structure VP4 proteins and mRNAs, 833 herpesvirus sylvilagus differences, 523 expression, 1661 Bovine viral diarrhea virus Cowpox virus hemagglutinin, 1661 thrombocytopenia in young calves, 3934 early transcription control Baculovirus vectors Brome mosaic virus cis-acting elements, 4632 hepatitis B virus surface antigen poly- 2a gene RNA polymerase peptides temperature-sensitive mutations, 5302 second-largest subunit, 1076 expression, 1549 coat protein N terminus, 4545 Coxsackievirus B3 influenza virus hemagglutinin, 1677 Budgerigar fledgling disease virus chimeric picornaviruses Sindbis virus 26S cDNA capsid protein VP2 3C substrate specificity, 3444 polyprotein processing, 1256 myristylation, 429 enterovirus-specific T-cell response, v-sis/PDGF-B protein BZLF1 gene 4148 expression and purification, 3080 Epstein-Barr virus, 3109 Coxsackieviruses simian sarcoma virus, 3080 group B YAC-1 mouse cell receptor, Baculoviruses Canine distemper virus 3105 Autographa californica nuclear polyhe- reactive oxygen species Creutzfeldt-Jakob disease agent drosis virus pathogenesis, 2790 physical properties, 1212 early promoter elements, 493 Canine parvovirus c-src transduction major capsid protein gene, 2008 avian sarcoma virus PR2257, 481 polarized entry AMP BALB sarcoma virus cell 3164 Cyclic ras gene epithelial line, adenovirus type 5 E4 expression, 3057 tumorigenesis, 1377 Caprine arthritis-encephalitis virus human T-cell leukemia virus type I B-cell growth factor interference, coinfections, intertypic vi- p40tax Epstein-Barr virus episomes rus enhancement trans-activator-responsive element, negative modulation, 3190 visna virus, 4682 3234 BK virus lentivirus-induced interferon Cytokines growth efficiency in vivo and in vitro, macrophage-virus interaction, 2578 interferon-inducible IFI-78K gene 3195 long terminal repeat transcriptional regulation, 2616 hybrid transformation, 863 regulatory elements, 4925 Cytomegalovirus, human origin of DNA replication, 356 Capripoxviruses a promoter-enhancer replication and transcription enhancer, genome comparison with orthopoxvi- iel transactivation, 1435 1514 ruses, 4703 cooperating DNA segments Bluetongue virus Capsid protein gene tumor progression, 425 type 10 NS3 proteins Autographa californica nuclear polyhe- early glycoprotein identification and expression by baculovirus recombi- drosis virus, 2008 expression, 3330 xii SUBJECT INDEX J. VIROL.

early proteins serotype specificity, 2486 env gene expression posttranscriptional regulation, 3117 nonstructural glycoprotein NS1 human immunodeficiency virus early gene promoters sequences in processing, 1852 rev regulation, 1959 temporal regulation, 281 pre-membrane protein cleavage, 3345 Envelope glycoproteins glycoprotein gp58 structural proteins Epstein-Barr virus-producing cells neutralizing epitope, 1995 immunization with recombinant vac- inner nuclear membrane localization, gp55-116 envelope glycoprotein complex cinia virus, 2853 828 processing, 403 DNA polymerase gene human immunodeficiency virus expres- host cell protein herpes simplex virus type 1 sion binding to pac-2, 4715 65K DNA-binding protein, 5023 epithelial basolateral surfaces, 978 immediate-early gene region aphidicolin-resistant mutants, 2874 Epstein-Barr virus early and late gene expression, 2699 drug sensitivity, 4913 anti-EBNA-l induction 2.7-kilobase RNA promoter in vitro mutagenesis, 4913 12-O-tetradecanoylphorbol- 13-acetate, early gene regulation, 5334 T4 tsL56 mutations, 4762 3315 late gene expression vaccinia virus mutants antigen regulation ICP36 activation, 1783 aphidicolin-resistant mutant, 4060 somatic cell hybrids, 2768 regulation, 1783 molecular genetic analysis, 841 BMLF1 enhancer element major capsid protein gene, 1345 Double-stranded RNA virus BRLF1 transactivation, 3878 major IE gene promoter-regulatory re- Saccharomyces cerevisiae viruses BMLF1 protein, 5276 gion overlapping genes, 3983 BZLF1 gene, 3109 cyclic AMP-response elements, 3026 Double-stranded RNAs BZLF1 immediate-early gene product membrane antigens interferon-inducible IFI-78K gene latent versus productive promoters, infected fibroblasts, 1485 transcriptional regulation, 2616 1729 membrane protein gene Drosophila S virus BZLF1 latency-disrupting gene conservation among human herpesvi- Reoviridae family expression, 1721 ruses, 3792 classification, 1007 cell-specific Z-response signal regions, mtrll colinear region, 2866 Duck hepatitis B virus 3040 pp65 gene core particle protein, 1371 cottontop tamarin infection early-late promoter activation, 1232 C terminus, 2995 gene expression, 1967 receptor-mediated fibroblast binding, distal pre-S region DR enhancer 3991 in-frame and frameshift mutations, functional domains, 615 strain AD169 25-kDa virion protein 4965 DR promoter gene expression, 233 neutralizing monoclonal antibodies transactivation, 607 Cytomegalovirus, murine epitope mapping, 2445 early antigen protein DNA in circulating leukocytes, 2667 P gene expression, 5451 NotI repeat encoded, 4609 Cytomegalovirus, primate EBNA 2A and EBNA 2B isolates assembly protein gene, 669 EIA proteins EBNA 3 proteins, 1031 Cytopathic effect adenovirus serine residue 89 EBNAI-binding sites avian hemangioma-inducing retrovirus mutation, 1569 oriP functions, 2657 envelope glycoprotein, 4325 phosphorylation, 1569 envelope glycoprotein localization, 828 Cytotoxic T lymphocytes adenovirus type 2 epithelial nasopharyngeal carcinoma dengue virus-specific cross-reactivity, 289R transactivating domain, 1495 cells 5086 Echovirus 6 cytopathic effects, 3555 murine leukemia viruses steady-state infection functional limits of oriP, 3016 LTR transcription, 1087 nonlytic viral RNA, 5268 gene BGLF4 rotavirus infection unprocessed capsid polypeptide, 5268 homology with herpes simplex and intestinal mucosal surface, 3507 Ecotropic murine leukemia virus varicella-zoster viruses, 450 simian rotavirus RRV strain 2, 3279 dual-virus etiology of motor neuron dis- new protein kinase-related gene, 450 Cytotoxic T-cell response ease glycoprotein gp85 depletion cytoplasmic measles virus antigens lactate dehydrogenase-elevating virus, virosome-cell fusion, 4998 HLA-DR-restricted presentation, 1756 4362 immediate-early gene product BMLF1 Cytotoxic T-lymphocyte clones infection of murine gonads, 2134 reporter-gene-dependent effect, 3870 lymphocytic choriomeningitis virus Ecotropic proviruses latent gene expression H-2Db restricted, 1845 polymerase chain reaction Burkitt's lymphoma cells, 1531 polymorphism, 1845 flanking DNA amplification, 1924 primary B cells, 1531 Cytotoxic T-lymphocyte response Embryonal carcinoma cells latent infection human immunodeficiency virus specific, recombinant Moloney murine leukemia activation, 445 2270 virus latent membrane protein lymphocytic choriomeningitis virus in- expression, 4431 human B-cell lines, 4079 fection Encephalomyocarditis virus toxicity, 2469 immunodominant region, 4303 3C precursors transforming domain, 2469 proteolytic cleavage, 1054 vimentin expression, 4079 Defective interfering particles 3C protease activity latent-infection membrane proteins, 933 poliovirus expression in mouse cells, 5013 MS gene promoter in vitro construction, 5386 central nervous system demyelination phorbol ester induction, 5062 Defective interfering RNA anti-T-cell antibodies, 4242 nuclear antigen EBNA-1 coronavirus leader sequence switching, internal entry by ribosomes DNA-binding properties, 101 5285 5' nontranslated region, 1651 Raji cells, 101 Dengue virus protein synthesis, 1651 origin of plasmid replication, 5505 cross-reactive CD8+ human cytotoxic T Enteroviruses oriP and oriLyt regions lymphocytes, 5086 cocksackievirus B3-specific T-cell re- RNA synthesis rates, 4938 murine T-lymphocyte responses sponse, 4148 promoter VOL. 63, 1989 SUBJECT INDEX xiii

EBNA-l transactivation, 2644 cleavage, 3345 Glycoprotein B receptor CR2 and Blast2/CD23 expres- tick-borne encephalitis virus envelope herpes simplex virus type 1 sion protein E monoclonal antibody-resistant mu- nasopharyngeal carcinoma cells, 4121 antigenic structure, 564 tants, 730 simian virus 40 hybrid shuttle vector West Nile virus membrane proteins Glycoprotein D recombination rate, 3837 cell-associated virus, 2521 herpes simplex virus strain correlation, 983 proteolytic cleavage, 2521 antigenic site II, 2325 T-cell-derived B-cell growth factor yellow fever virus polyprotein process- ICP4-binding sites, 2510 negative modulation, 3190 ing, 4199 interference mediation, 819 trans-activator genes Foot-and-mouth disease virus Glycoprotein gB protein identification, 938 cell heterogeneity equine herpesvirus 4 Equine herpesvirus 1 BHK-21 cells, 59 identification and nucleotide sequence, capsomer protein stoichiometry, 3777 trans-acting cellular products 1123 glycoprotein gpl3 gene resistance, 2385 Glycoprotein gC expression in recombinant vaccinia type A12 antigenic sites, 2143 herpes simplex virus type 1 virus, 4189 Friend murine leukemia virus pseudorabies virus gIII gene, 4055 replication origin, 1275 enhancer region binding sites Glycoprotein gH spliced immediate-early transcript nuclear factors, 4210 herpes simplex virus mapping, 5101 enhancer region segments neutralizing antibodies, 3435 Equine herpesvirus 4 erythroleukemogenicity, 328 Glycoprotein gIII glycoprotein gB gene human c-fps/fes proto-oncogene pseudorabies virus identification and nucleotide sequence, retroviral vector, 5469 herpes simplex virus type 1 gC gene, 1123 transforming activity, 5469 4055 Equine infectious anemia virus Friend spleen focus-forming virus host cell interactions, 3323 long terminal repeat env-related gene pseudorabies virus Bartha strain regulatory elements, 4925 glycoprotein gp55 product, 4824 envelope protein localization, 250 replication in vitro, 2492 single base insertion, 4824 Glycoprotein gpl viral DNA, 5194 interleukin-3-dependent hematopoietic varicella-zoster virus phosphorylation ets sequences cells mammalian casein kinases, 3912 avian leukemia virus E26 splenic accumulation, 4434 gpl2O murine retroviral recombinant, 205 leukemogenic membrane glycoprotein human immunodeficiency virus type 1 avian retrovirus E26 gp55 immunization of chimpanzees, 5046 erythroblastosis in chickens, 398 processing, 3561 proviral integration site, 4958 H-l virus Feline endogenous RD-1 14 proviruses Fungal viruses transformation supports permissiveness, long terminal repeats Saccharomyces cerevisiae dsRNA vi- 2152 enhancer elements, 4234 ruses Ha-ras oncogene Feline herpesvirus 1 overlapping genes, 3983 transformed NIH 3T3 cells thymidine kinase gene Fusion glycoprotein PEBP1 response, 3669 polymerase chain reaction, 3240 Newcastle disease virus Fl and F2 sub- 12-O-tetradecanoylphorbol- 13-acetate, Feline immunodeficiency virus unit mutations 3669 peritoneal macrophage infection, 5483 monoclonal antibody neutralization, Harvey murine sarcoma virus Feline infectious peritonitis 952 transformation and oncogenicity, 1384 coronavirus infection Fv-4 gene Harvey sarcoma virus feline macrophage resistance, 436 murine leukemia virus ras gene virulence, 436 ecotropic interference, 5405 tumorigenesis, 1377 Feline leukemia virus fyn gene product Heat shock protein env gene polyomavirus middle T antigen oncogenicity of adenovirus-transformed endogenous proviral loci, 2379 transformed rat cells, 2343 cells nucleotide sequence, 2379 hsp27, 3368 envelope glycoprotein gp7O G protein polyomavirus middle T antigen, 4533 posttranslational modifications, 189 vesicular stomatitis virus San Juan and Heat shock proteins 70 myc-containing recombinant provirus Orsay strains SV40 large T antigen and Xenopus laevis FTT glycosylation requirement, 3801 p53 structure, origin, transforming activ- intracellular transport, 3801 interaction, 3894 ity, 2108 gag gene products Helper virus Feline panleukopenia virus mouse mammary tumor virus, 2543 Abelson murine leukemia virus P38 promoter Rous sarcoma virus particle formation pre-B- and T-cell lymphomas, 2088 regulated expression, 2737 expression in mammalian cells, 4331 Hemagglutinin Feline sarcoma virus Gardner-Rasheed feline sarcoma virus influenza A virus Gardner-Rasheed strain actin domain cleavability, 32% mutational analysis, 1174 kinase and transforming activities, influenza virus mutation p70gag-acin-fgr domains, 1174 1715 specificity, 4298 Gardner-Rasheed strain actin domain p70gag-actin-fgr domains influenza virus synthesis kinase and transforming activities, mutational analysis, 1174 insect larvae, 1677 1715 Gibbon ape leukemia virus Hepadnaviruses FH3 avian retrovirus AP-1 consensus sites, 1737 selective encapsidation of RNA, 4257 v-myc proto-oncogene, 5092 human T-cell leukemia virus envelope Hepatitis A virus Filamentous bacteriophages glycoproteins cDNA attenuation and adaptation packaging signal, 3284 hybrid formation, 2374 genetic analysis, 5364 Flaviviruses Moloney murine leukemia virus core, simian PA21 strain dengue virus pre-membrane protein 2374 comparison with human strains, 4932 xiv SUBJECT INDEX J. VIROL.

Hepatitis B virus gene UL13 3513 core antigen homology with varicella-zoster and in vitro-activated immune cells proteaselike sequence, 2598 Epstein-Barr viruses, 450 retinitis in mice, 4808 core and e antigen polypeptides new protein kinase-related gene, 450 latency-associated DNA properties in E. coli, 4645 glycoprotein B mar mutations, 730 chromatin structure, 943 core and e antigens glycoprotein D latency-associated transcripts antigenic determinants, 798 antigenic site II, 2325 infected murine sensory neurons, 4455 core gene promoter and enhancer ICP4 DNA-binding properties, 696 thymidine kinase-negative mutants, liver-specific expression, 919 immediate-early promoters 2861 core protein cellular NFIII-binding sites, 2798 latent expression of globin, 3844 cell surface expression, 5399 ocular immunopathology Pol-stimulating protein DNA integrations, 2638 CD4+ lymphocyte mediation, 769 65K DNA-binding protein, 5023 e antigen selective spread in central nervous sys- regulatory protein ICP4 aspartyl protease site mutagenesis, tem intragenic complementation, 1203 5497 ocular inoculation, 4756 resident peritoneal macrophages biosynthesis, 5497 Spl-binding sites, 4088 replication restriction, 2300 enhancer and nuclear factors thymidine kinase gene ribonucleotide reductase, 3769 interaction, 5293 conserved ORF, 1839 spinal ganglia infections human beta interferon gene thymidine kinase gene induction, 4088 thymidine kinase mutant, 4976 transcription, 3065 types 1 and 2 invasiveness regions, 1153 synergism of interferon and tumor ne- human liver plasma membrane receptors Vmw65 structural domains crosis factor pre-SI region, 1981 protein A fusion polypeptides, 5509 replication blockage, 1354 pre-S2 region, 1981 protein-DNA complex formation, 5509 transcriptional regulatory protein ICP4 interferon Herpes simplex virus type 1 autoregulation and transactivation, replication inhibition, 2936 65K DNA-binding protein 3714 P gene expression, 5451 kinetics of expression, 137 DNA-binding activity, 3714 precore protein transport, 5238 a sequence-specific proteins, 1059 primary structural components, 3714 promoter regulation a protein ICP27 UL8 gene product tissue-specific enhancer, 579 activator and repressor functions, 4590 DNA synthesis, 591 promoter and specific binding protein, separable regulatory activities, 3399 ICP6::1acZ insertion mutant, 591 2914 aphidicolin-resistant mutants Us/Rs junction putative protease and reverse DNA polymerase substrate specificity, duplication, 1877 transcriptase domains 2874 virion host shutoff function, 4834 doubly spliced transcript, 4165 capsid assembly gene, 2169 control of mRNA stability, 1897 reverse transcriptase capsid protein localization Vmw65 mutant, 2260 pol gene, 1019 Ar+ plasma etching, 4697 Vmw65-octamer-binding factor interac- selective encapsidation of RNA, 4257 deletion mutant tion, 1641 signal peptide cleavage, 5238 latency-associated transcript, 2893 Herpes simplex virus type 2 spliced RNA species, 4011 DNA polymerase gene ICP4 and ICP22/47 promoter mutants, surface antigen expression drug sensitivity, 4913 2036 regulation in transgenic mice, 4069 in vitro mutagenesis, 4913 IE elements in ICP10 surface antigen gene expression Fc receptor ribonucletoide reductase large subunit, regulation, 3919 novel function, 4479 2773 surface antigen polypeptides gene products protein kinase activity in ICP1O, 3389 baculovirus expression system, 1549 DNA replication, 196 Herpes simplex virus types 1 and 2 surface antigen-specific human T cells overexpression, 196 cell surface heparan sulfate DPw4 restriction, 747 glycoprotein D binding, 52 X gene product asparagine-linked oligosaccharides, Herpesvirus of turkeys transactivation, 4019 5184 thymidine kinase gene, 2847 X gene product transactivation glycoprotein gC gene Herpesvirus saimiri human immunodeficiency virus LTR, pseudorabies virus glll gene, 4055 deletion mutants 2857 glycoprotein H transformation ORF, 3307 Hepatitis delta virus antigenic properties, 4744 oncogenicity in rabbits, 3601 cloned cDNA expression in ts COS cells, 4744 selectable recombinant infectivity in chimpanzees, 4292 ICPO, 4579 human T-cell line, 1818 delta antigen ICP4 autoregulation and TATA involve- Herpesvirus sylvilagus replication role, 1945 ment, 3737 repetitive sequence arrangement, 1010 nucleic acids, 1612 ICP4 DNA-binding function, 2497 Herpesviruses Herpes simplex virus ICP4 regulatory protein bovine herpesvirus 1 acute and latent infection purified virions, 3338 T-cell proliferation, 1525 C57BL/6 mice, 1480 ICP8 DNA-binding protein equine herpesvirus 1 antigen-presenting liposomes multiple nuclear functions, 5258 capsomer protein stoichiometry, 3777 treatment, 2951 ICP27 deletion mutants, 18 equine type 1 immediate-early transcript anti-gH neutralizing antibodies immediate-early gene mutants mapping, 5101 penetration blocked, 3435 latency establishment and reactiva- feline herpesvirus 1 thymidine kinase cellular gene regulation, 1929 tion, 759 gene DNA amplification, 3683 immediate-early protein ICP4 polymerase chain reaction, 3240 estrogen receptor mRNA levels CD4+ cells, 1861 herpes simplex virus, varicella-zoster MCF-7 cell stimulation, 2388 human immunodeficiency virus repli- virus, and Epstein-Barr virus gD gene cation, 1861 new protein kinase-related genes, 450 ICP4-binding site, 2510 immediate-early protein Vmwl 1O human cytomegalovirus membrane pro- gD-induced interference, 819 latent herpes simplex virus type 2, tein gene VOL. 63, 1989 SUBJECT INDEX xv

conservation, 3792 genital mucosal transmission of SIV cell surface expression, 4074 human herpesvirus 6 animal model for heterosexual trans- NF-KB binding sites, 4919 CD4 T-lymphocyte tropism, 3161 mission, 4277 NF-KB-mediated activation, 4097 human herpesvirus 6-specific proteins herpes simplex virus type 1 protein ICP4 p17 core protein infected human T cells, 2835 CD4+ cells, 1861 characterization and epitope mapping, H-ras locus replication potentiation, 1861 267 retroviral activation, 2959 human interferon gene expression neutralizing monoclonal antibodies, Human B-lymphotropic herpesvirus NF-KB-like binding, 2557 267 unique DNA polymerase, 1400 pathogenic variants, 2118 p24 core protein Human cytomegalovirus promoter transactivation immunoreactive domains, 4064 a promoter-enhancer human herpesvirus 6, 970 TrpE/Gag fusion proteins, 4064 iel transactivation, 1435 rev protein protease mutational analysis cooperating DNA segments phosphorylation, 4438 homology with aspartic proteinases, tumor progression, 425 tat protein 111 early glycoprotein identification and structural and functional characteriza- purified recombinant CD4 expression, 3330 tion, 1 inhibition in vitro, 4370 early proteins tumor necrosis factor rev gene function posttranscriptional regulation, 3117 cytocidal effect, 2504 lymphoid cell replication, 4875 early gene promoters Human immunodeficiency virus type 1 polymerase chain reaction, 4875 temporal regulation, 281 azidothymidine and neutralizing anti- rev (trslart) protein, 1265 glycoprotein gp58 body RNA packaging, 4085 neutralizing epitope, 1995 cell-to-cell transmission, 2361 RNase H inhibition gp55-116 envelope glycoprotein complex CD4 T4A epitope sulfated polyanions, 5489 processing, 403 human fetal dorsal root ganglion glial structural proteins host cell protein cells, 5054 epitope mapping system, 3525 binding to pac-2, 4715 CD4+ T cells, 4626 monoclonal antibodies, 3525 immediate-early gene region CD4-independent infection of neural synthetic peptide early and late gene expression, 2699 cells, 2527 antiproliferative activity, 3257 2.7-kilobase RNA promoter cytotoxic T-lymphocyte response, 2270 sequence identity to gp4l, 3257 early gene regulation, 5334 DNA-protein-binding domain, 3213 tat gene late gene expression enhancer stimulation mutagenesis, 1181 ICP36 activation, 1783 HTLV-I tax gene product, 1578 trans-activation-responsive element regulation, 1783 envelope glycoprotein glycosylation sequence specificity, 5501 major capsid protein gene, 1345 monensin effects, 2452 U5-specific element major IE gene promoter-regulatory re- envelope glycoprotein gpl20 polyadenylation, 421 gion immunization of chimpanzees, 5046 UV-induced expression, 4540 cyclic AMP-response elements, 3026 envelope glycoprotein gpl60 variant virus-specific protease membrane antigens expression and immunogenicity, 3489 protein maturation and infectivity, infected fibroblasts, 1485 envelope glycoprotein precursor gpl60, 2550 membrane protein gene 4670 vpr open reading frame conservation among human herpesvi- envelope proteins mutational analysis, 4110 ruses, 3792 expression, 129 vpu protein analyses, 3784 mtrll colinear region, 2866 recombinant human adenovirus, 129 Human immunodeficiency virus type 2 pp65 gene extracellular glycoprotein mutations envelope glycoprotein processing, 647 early-late promoter activation, 1232 receptor binding, 4464 long terminal repeat trans activation, receptor-mediated fibroblast binding, gag and pol gene expression 5006 3991 vaccinia virus recombinant, 1451 Human immunodeficiency virus types 1 strain AD169 25-kDa virion protein gag polyprotein precursor and 2 gene expression, 233 N myristylation, 3176 antibody-dependent cellular cytotoxicity Human endogenous retroviruses gp4l oligomeric structure, 2674 type- and strain-specific antigens, 3376 type II family ancestry, 4982 gpl20 domains protein R mutations Human hepatitis delta virus interaction, 3595 replication and cytopathogenicity, self-ligating RNA sequences, 1428 gpl20 folding and glycosylation, 639 3205 Human herpesvirus 6 group-specific neutralizing monoclonal Human papillomavirus type 6b CD4 T-lymphocyte tropism, 3161 antibodies LI ORF-encoded immunoreactive human immunodeficiency virus promoter CD4-binding domain, 3579 epitopes, 809 transactivation, 970 gpl20, 3579 Human papillomavirus type 11 infected human T cells infection of human monoblastoid cells, enhancer function virus-specific proteins, 2835 3700 primary keratinocytes, 957 Human immunodeficiency virus interleukin-1 and tumor necrosis factor enhancer and transcription factor antibody-dependent cell-mediated cyto- induction via CD4 receptor, 4404 regulation, 2967 toxicity long terminal repeat Human papillomavirus type 16 antigenic specificity, 584 hepatitis B virus gene X transactiva- catenated episomes DNA and RNA synthesis tion, 2857 cervical carcinoma cells, 782 differential gene expression, 3708 SPI-binding domains, 2585 E6 and E7 genes env gene expression transcriptional regulation in vivo, 2585 primary human keratinocyte transfor- rev regulation, 1959 long terminal repeat mutations mation, 4417 envelope glycoprotein expression replication effect, 4115 E7 protein epithelial basolateral surfaces, 978 LTR and EIAIElB activation point mutational analysis, 2650 envelope protein gpl60 multiple transcriptional regulatory do- human embryonic fibroblast transforma- surface CD4 depletion, 3748 mains, 4616 tion genetic recombination, 1455 major core protein p25 ORFs E6 and E7 expression, 965 xvi SUBJECT INDEX J. VIROL.

nuclear protein binding, 1142 Human rotaviruses Immediate-early protein transforming gene, 1465 RNA-RNA hybridization pseudorabies virus promoters Human papillomavirus type 18 relation to feline rotavirus, 1431 class II gene binding, 1869 E2 gene product strain K8 protein VP4 gene Immune response regulation in human keratinocytes, neutralization epitopes, 4101 anti-idiotypic antibodies to influenza 4317 nucleotide sequence, 4101 virus, 2758 E6 protein expression Human T-cell leukemia virus herpes simplex virus type 1 baculovirus vector, 366 gibbon ape leukemia virus envelope gly- retinitis in mice, 4808 DNA-binding properties, 366 coproteins SAll and rhesus rotaviruses intracellular localization, 366 hybrid formation, 2374 reassortment in vivo, 4525 gene expression Moloney murine leukemia virus core, solid-matrix-antibody-antigen complexes herpes simplex virus type 1 activation, 2374 multiple viruses, 1808 555 Human T-cell leukemia virus type I Influenza A virus 12-O-tetradecanoylphorbol-13-acetate CD2 pathway avian H5 hemagglutinin activation, 555 T-lymphocyte activation, 5413 pathogenicity, 3453 transforming genes, 1247 c-fos gene trans activation hemagglutinin cleavage, 3296 Human papillomavirus type 27 p40w protein, 3220 hemagglutinin and neuraminidase genome characterized and cloned, 4904 gp6l env gene immunogenic differences, 1239 homology to type 2, 4904 antibody reactivity, 4952 matrix protein Human papillomavirus type 28 human immunodeficiency virus type 1 anti-idiotypic antibodies, 3586 genome characterized and cloned, 4905 enhancer ribonucleoprotein-binding sites, 3586 relation to types 3 and 10, 4905 tax gene product, 1578 PB1 gene Human papillomavirus type 29 long terminal repeat avian-to-human transmission, 4603 cross-hybridization with types 2 and 3, cyclic AMP response, 1604 Influenza B virus 4906 long terminal repeat induction NB and NA glycoproteins genome characterized and cloned, 4906 12-O-tetradecanoylphorbol- 13-acetate, bicistronic mRNA function, 28 Human papillomavirus type 48 2987 synthesis, 28 genome characterized and cloned, 4907 p40' trans-activator-responsive ele- Influenza C virus Human papillomavirus type 49 ment, 3234 esterase genome characterized and cloned, 4909 primary human T cells catalytic site, inhibition, and possible type 5 alignment, 4909 antisense RNA expression, 677 function, 2056 Human papillomavirus type 50 inhibition, 677 Influenza virus epidermodysplasia verruciformis, 4910 pX genes in transgenic mice AIWS/33, WSN, and A/PR/8/34 replica- genome characterized and cloned, 4910 thymic atrophy, 3185 tion Human papillomavirus type 53 transcriptional activator tax hemagglutinin cleavage, 1695 genome characterized and cloned, 4911 signal transduction pathway, 3761 MI protein expression, 1695 related to type 30, 4911 Human T-cell leukemia virus type II anti-idiotypic antibodies Human papillomavirus types 6b and 11 gag, pro, and pol gene products immune response, 2758 E7 mRNA, 1441 translation, 2400 A/WS/33, WSN, and AIPR/8/34 replica- Human papillomavirus types 16, 18, 31, Moloney murine leukemia virus chime- tion and 33 ras differentiating mouse brain cells, 1704 keratinocyte immortalization tax effect on chromatin structure, 3072 hemagglutinin peptide cervical carcinoma association, 159 Human T-cell leukemia virus types I and T-cell clones, 3087 Human papillomavirus types 43 and 44 II hemagglutinin specificity, 4298 association with condylomas and cervi- tax genes hemagglutinin synthesis cal neoplasia mutagenesis, 1474 insect larvae, 1677 cloning and DNA sequencing, 2829 Human T-lymphotropic virus types I and M protein (Ml) Human papillomaviruses II antigenic analysis, 3622 group heterogeneity, 4898 antiproliferative octapeptide, 3250 monoclonal antibody localization, 3622 progesterone and glucocorticoid monoclonal antibody-resistant mutants response elements ICP4 protein phenotypic hiding, 4107 long control regions, 3261 herpes simplex virus RNA polymerase promoter, 5142 Human parainfluenza virus type 3 DNA-binding properties, 696 synergism of bacterial protease, 2252 fusion glycoprotein herpes simplex virus type 1 Interferon antigenic and functional organization, association with purified virions, 3338 beta and gamma interferons 375 autoregulation and transactivation, synergistic effects, 4569 Human rhinovirus 3714 hepatitis B virus replication, 2936 P2 protein DNA-binding activity, 3714 hepatitis B virus transcription, 3065 gene 3737 herpes simplex virus type 1 blockage host range regulation, change, 2396 intragenic complementation, 1203 synergism with tumor necrosis factor, type 14 3C protease structural requirements, 3714 1354 expression in E. coli, 5037 TATA involvement, 3737 human immunodeficiency virus enhancer peptide cleavage, 5037 ICP8 protein NF-KB-like binding, 2557 type 14 neutralization herpes simplex virus DNA-binding pro- interferon-inducible IFI-78K gene monoclonal antibodies and Fab frag- tein transcriptional regulation, 2616 ments, 36 multiple nuclear functions, 5258 lymphocytic choriomeningitis virus dis- Human rhinovirus 14 Immediate-early genes ease chimeric picornaviruses herpes simplex virus anti-gamma interferon-treated mice, 3C substrate specificity, 3444 cellular NFIII-binding sites, 2798 2813 conformational change herpes simplex virus type I mutants replication enhancement, 2813 adsorption, 2002 latency establishment and reactiva- macrophage-virus interaction drug-resistant mutants, 2476 tion, 759 caprine arthritis-encephalitis virus, VOL. 63, 1989 SUBJECT INDEX xvii

2578 Latency-associated transcripts neoplasia induced, 2204 mouse natural autoantibodies herpes simplex virus type 1 vesicular stomatitis virus challenge, P-globin mRNA expression, 3844 Macrophages 955 infected murine sensory neurons, 4455 beta interferon expression, 2785 murine macrophage expression, 2785 thymidine kinase-negative mutants, lentivirus-induced interferon, 2578 Interleukin- 1 2861 Major histocompatibility complex class I human immunodeficiency virus type 1 herpes simplex virus type 1 deletion mu- adenovirus type 12 EIA induction via CD4 receptor, 4404 tant, 2893 expression regulation, 4039 Interleukin-2 Latency-related RNAs simian virus 40 cell surface receptors, lymphokine-activated killer cells pseudorabies virus 4474 antiviral effect, 4969 swine trigeminal ganglia, 2908 Major late promoter Interleukin-3 Latent infection adenovirus attenuation in monkey cells, Friend erythroleukemia bovine leukemia virus 4093 hematopoietic cells, 4434 activation in blood cells, 2099 adenovirus downstream element, 5124 splenic accumulation, 4434 Epstein-Barr virus BZLF1 immediate- Marek's disease herpesvirus Intracisternal A particles early gene product, 1729 BamHI-H gene family, 2534 B-cell lymphoma differentiation, 659 herpes simplex virus IE protein retrovirus-induced lymphoid leukosis expression induction, 659 VmwllO, 3513 augmentation, 504 herpes simplex virus type 1 DNA Marek's disease virus JC virus nucleosome chromatin structure, 943 loss of tumorigenicity, 4129 cell type-specific expression herpes simplex virus type 1 latency-as- Matrix protein positive and negative regulation, 463 sociated transcripts influenza A virus ribonucleoprotein- chimeric DNAs murine sensory neurons, 4455 binding sites transformation, 2180 varicella-zoster virus anti-idiotypic antibodies and synthetic hybrid transformation, 863 rat sensory neurons, 3155 peptides, 3586 renal and bone marrow transplant pa- Latent membrane protein MCF13 virus tients, 4445 Epstein-Barr virus nuclear antigens nuclear proteins 5-azacytidine effect, 3135 differential DNA binding, 4945 Killer T cells Epstein-Barr virus transforming domain Measles virus polyomavirus DNA damage, 572 toxicity, 2469 HLA-DR-restricted cytotoxic T-lympho- Epstein-Barr virus-infected cells cyte response, 1756 La Crosse virus vimentin expression, 4051 human peripheral blood mononuclear base-paired RNAs, 122 Epstein-Barr virus-infected human B-cell cells mRNA synthesis requirement lines temperature-sensitive mutant, 689 cell-type dependency, 5159 vimentin expression, 4079 poly(A)+ RNA synthesis in vivo, 2977 nucleocapsid protein synthesis Lentiviruses subacute sclerosing panencephalitis mosquito cells, 5166 interferon and macrophage-virus interac- strain Lactate dehydrogenase-elevating virus tion, 2578 matrix gene hypermutation, 5464 dual-virus etiology of motor neuron dis- ovine-caprine lentiviruses Mengovirus ease interference, 4682 RNA transcripts ecotropic murine leukemia virus, 4362 visna virus F(ab')2 fragments cloning and synthesis, 1822 Large T antigen infectivity in macrophages, 1811 poly(C) tracts, 1822 polyomavirus mutation Linker insertion-deletion mutagenesis 3-Methylcholanthrene DNA synthesis, 776 v-src gene mutants, 542 mouse mammary tumor virus proviral DNA-binding specificity, 242 LuIlI virus amplification simian virus 40 NSI (rep) protein lymphomas of RF/J mice, 3200 age-dependent epitope changes, 2352 DNA replication, 4249 N-Methyl-N-nitrosourea biochemical activities, 2308 Lymphocytic choriomeningitis virus mouse mammary tumor virus proviral nuclear subcompartmentalization, 2308 anti-gamma interferon-treated mice amplification p53 complex modulation, 1310 replication enhancement, 2813 lymphomas of RF/J mice, 3200 papillomas of transgenic mice, 790 cytotoxic T-lymphocyte epitope Middle T antigen transforming functions, 5459 immunodominant region, 4303 murine polyomavirus-transformed cells zinc finger region, 94 H-2Df-restricted CTL clones p60W' association, 2343 simian virus 40 expression in monkey polymorphism, 1845 polyomavirus human 70-kDa heat shock cells recombinant vaccinia virus protein, 4533 engineered vaccine, 4311 polyomavirus replication, 5478 T-cell epitope expression, 4311 Mink cell focus-forming murine leukemia simian virus 40 linker insertion mutants ribavirin-susceptible block viruses trans-dominant interference, 4777 replication, 1827 enhancer sequences simian virus 40 and p53, 3362 RNA-dependent RNA polymerase activ- leukemia acceleration, 1284 simian virus 40 structural regions ity Pmv loci in recombinant inbred mice ts mutants, 4426 synthesis in vitro, 1938 strain distribution patterns, 3810 simian virus 40-transformed cells Lymphokine-activated killer cells Minute virus of mice cellular heat shock protein, 3961 chemotaxis and migration to infection adenovirus type 2-host nucleoli interac- simian virus 40-transformed mKS-A sites tions, 3651 cells, 2820 antiviral effect, 4969 conditional cell susceptibility simian virus 40-transformed mouse tu- interleukin-2, 4969 v-src induced, 4797 mor cells Lymphoproliferative disease virus of tur- DNA interaction with nuclear matrix, plasma membrane association, 3926 keys 4344 Large T-antigen mutants molecular cloning, 2877 DNA replication ligation step, 1002 simian virus 40 DNA replication Lymphotropic papovavirus NS-1 polypeptide localization, 3902 multiple initiation steps, 4181 transgenic mice P4 promoter mutants, 5425 xviii SUBJECT INDEX J. VIROL.

Mlvi-J locus Mouse adenovirus type 1 T-lymphoma cell-specific element, 76 Moloney murine leukemia virus unusual E3 region, 5455 UAA and UGA termination codons pvt-lIMis-J locus, 2366 Mouse autoantibodies suppression, 2870 Moloney leukemia virus vesicular stomatitis virus challenge Murine retrovirus H-ras proto-oncogene, 2959 alpha and beta interferons, 955 amphotropic packaging cell line Moloney murine leukemia virus Mouse hepatitis virus cell cycle dependency, 3865 B2mb gene defective interfering RNA T-lymphocyte infection efficiency, retroviral provirus integration, 2623 high-frequency leader sequence 3865 enhancer region segments switching, 5285 internal attachment site erythroleukemogenicity, 328 gene 2b integration, 2844 F9 embryonal carcinoma cells RNA transcription regulation, 3729 Murine retroviruses expression, 2317 gene A polyprotein LTR enhancer regions gibbon ape leukemia virus and human autoprotease activity, 3693 interactions, 3353 T-cell leukemia virus envelope gly- Mouse hepatitis virus JHM Murine sarcoma virus coproteins T-cell-mediated clearance transformed NIH 3T3 cells hybrid formation, 2374 central nervous system, 3051 2'-5'-oligoadenylate synthetase expres- human T-cell leukemia virus type II chi- Mouse mammary tumor virus sion, 1116 meras chemically induced lymphomas of RF/J Murine T-lymphocyte responses tax effect on chromatin structure, 3072 mice dengue virus-specific proliferation maternal transmission, 1049 proviral amplification, 3200 serotype specificity, 2486 Mlvi-J and pvt-lIMis-J loci, 2366 gag proteins, 2543 Mutational analysis MoMuLV-TB virulence int-i and int-2 loci visna virus long terminal repeat, 3001 mapping, 471 tumorigenesis in C3Hf mice, 4972 Myeloblastosis-associated virus type 1 nucleocapsid protein non-mammary tumor cells proviral DNAs Cys-His box mutants, 1558 amplification, 456 nephroblastoma induction, 1803 palindromic LTR-LTR junction pathogenic clone Myristylation proviral integration, 2629 isolation, 148 budgerigar fledgling disease virus recombinant expression, 4431 phorbol ester-inducible T-cell-specific capsid protein VP2, 429 retrovirus promoter trap, 3227 expression, 3466 reverse transcriptase putative int domain, 1448 Nasopharyngeal carcinoma cells RNase H inhibition, 1460 Mumps virus Epstein-Barr virus receptor CR2 and U5 region deletion mutants small hydrophobic protein gene Blast2/CD23 expression, 4121 reverse transcription, 319 mRNA sequence, 1413 Epstein-Barr virus replication RNA packaging, 319 Murine AIDS cytopathic effects, 3555 UAA and UGA termination codons viral and genetic factors, 1223 Nephroblastomas suppression, 2870 Murine coronaviruses myeloblastosis-associated virus type 1 unmyristylated Pr5gag conserved epitope, 1408 proviral DNAs, 1803 assembly and maturation events, 2370 Murine cytomegalovirus Newcastle disease virus Monoclonal antibodies DNA in circulating leukocytes, 2667 fusion protein Fl and F2 subunit muta- duck hepatitis B virus Murine leukemia virus tions epitope mapping, 2445 cytotoxic T lymphocytes and T- monoclonal antibody neutralization, encephalomyocarditis virus lymphoma cells 952 CNS demyelination, 4242 LTR transcription, 1087 receptorless mouse FM3A cell mutants, human immunodeficiency virus type 1 dual-virus etiology of motor neuron dis- 182 gpl20 ease NF-KB group-specific neutralization, 3579 lactate dehydrogenase-elevating virus, human immunodeficiency virus type 1 human immunodeficiency virus type 1 4362 enhancer activation, 4097 p17 core protein ecotropic infection of murine gonads, NF-KB binding sites characterization and epitope mapping, 2134 human immunodeficiency virus type 1 267 endogenous xenotropic Xmv proviruses LTR, 4919 neutralization, 267 Fv-1 restriction locus, 1763 N-ras oncogene human immunodeficiency virus type 1 genetic analysis, 1763 oncogenicity in retroviral vectors, 3944 structural proteins Fv-1-sensitive retrovirus packaging sys- Nuclear antigens epitope mapping system, 3525 tem, 2592 Epstein-Barr virus EBNA-1 human parainfluenza type 3 virus fusion Fv4 resistance gene, 5405 DNA-binding properties, 101 protein, 3755 gag gene amber codon Raji cells, 101 human rhinovirus 14 translational readthrough, 2405 Epstein-Barr virus expression neutralization, 36 tRNA alteration, 2405 5-azacytidine, 3135 influenza virus M protein (Ml) interleukin-3-dependent hematopoietic latent membrane proteins, 3135 antigenic analysis, 3622 cells Nuclear factor III Newcastle disease virus fusion protein splenic accumulation, 4434 herpes simplex virus IE promoters Fl and F2 subunit mutations, 952 long terminal repeats cellular binding sites, 2798 porcine rotavirus serotypes relative expression, 5201 Nuclear localization neutralizing antibodies, 3545 LTR enhancer regions adenovirus type 5 EIA gene product simian virus 40 small t antigen, 3128 interactions, 3353 Xenopus oocytes, 4047 Theiler's murine encephalomyelitis virus LTR promoter and enhancer elements Nuclear oncogenes athymic mouse survival, 2081 negative regulation, 2746 P135gag-myb-e,s and p61/63mYc vesicular stomatitis virus mutants MCF13 and akv nuclear proteins neuroretina cell transformation, 3382 phenotypic masking, 5030 differential DNA binding, 4945 Nucleocapsid proteins Monoclonal antibody-resistant mutants Pmv loci in recombinant inbred mice La Crosse virus influenza virus strain distribution patterns, 3810 synthesis in mosquito cells, 5166 phenotypic hiding, 4107 SL3-3 virus enhancer core Moloney murine leukemia virus mutants VOL. 63, 1989 SUBJECT INDEX xix

Cys-His box, 1558 immunoreactive epitopes, 809 Paramyxoviruses type 11 enhancer function bovine parainfluenza 3 virus envelope 2'-5'-Oligoadenylate synthetase primary keratinocytes, 957 protein genes murine sarcoma virus-transformed cells type 11 enhancer regulation recombinant vaccinia viruses, 3661 expression, 1116 enhancer and transcription factor, syncytium formation, 3661 Oncogenicity 2967 fusion protein adenovirus-transformed cells type 16 catenated episomes cleavage site deletion mutants, 1293 heat shock protein hsp27, 3368 cervical carcinoma cells, 782 Parvovirus H-1 Orthopoxviruses type 16 E6 and E7 genes early protein NSI genome comparison with capripoxvi- primary human keratinocyte transfor- replication in human cells, 349 ruses, 4703 mation, 4417 Parvovirus LullI vaccinia virus protein type 16 E7 protein encapsidation, 3180 conservation, 1814 point mutational analysis, 2650 Parvoviruses synthetic peptide, 1814 type 16 nuclear protein binding, 1142 Aleutian mink disease virus type 16 transformation antibody transfer, 9 p40' human embryonic fibroblasts, 965 pneumonia, 9 human T-cell leukemia virus type I ORFs E6 and E7 expression, 965 autonomous LullI virus NS1 (rep) pro- c-fos gene trans activation, 3220 type 16 transforming gene, 1465 tein trans-activator-responsive element, type 18 E2 gene product DNA replication, 4249 3234 regulation in human keratinocytes, autonomous minute virus of mice p53 oncogene 4317 DNA replication ligation step, 1002 adenovirus type 5 Elb 58-kDa protein type 18 E6 protein expression autonomous minute virus of mice NS-1 complex formation, 1792 baculovirus vector, 366 polypeptide ras oncogene cooperation, 739 DNA-binding properties, 366 localization, 3902 simian virus 40 large T antigen intracellular localization, 366 B19 virus GC-box motif complex modulation, 1310 type 18 gene expression transcription control, 4814 interaction, 3894 herpes simplex virus type 1 activation, B19 virus propagation simian virus 40 mutant T antigen, 3362 555 erythroid lineage cells, 2422 p53-plus-ras-transformed cells 12-O-tetradecanoylphorbol- 13-acetate canine parvovirus entry tumor-specific transplantation antigen activation, 555 epithelial cell line, 3164 cross-reactive activity, 5440 type 18 transforming genes, 1247 H-1 virus p60c-src type 27 genome transformation supports permissive- partial activation in chicken embryo fi- cloning and characterization, 4904 ness, 2152 broblasts, 683 homology to type 2, 4904 LuIII encapsidation, 3180 p7ogag-actin-fgr type 28 genome minute virus of mice prototype strain Gardner-Rasheed feline sarcoma virus cloning and characterization, 4905 v-src-induced cell susceptibility, 4797 mutational analysis, 1174 relation to types 3 and 10, 4905 Pepper mild mottle virus Packaging cell lines type 29 genome variability and evolution, 2198 spleen necrosis virus cloning and characterization, 4906 Phorbol esters helper sequences, 3209 cross-hybridization with types 2 and 3, Epstein-Barr virus MS gene promoter Papillomavirus, bovine 4906 induction, 5062 E2 protein type 48 genome Phosphorylation trans activation in S. cerevisiae, 4422 cloning and characterization, 4907 adenovirus type 5 DNA-binding protein multiple E2 gene products type 49 genome mutations genetic assignment, 3151 cloning and characterization, 4909 synthesis, 5228 type 1 El mutants type 5 alignment, 4909 varicella-zoster virus glycoprotein oli- transforming activity, 1775 type 50 genome gosaccharides, 4264 type 1 E2 phosphorylation sites, 5076 cloning and characterization, 4910 Picornaviruses type 1 E5 peptide domains epidermodysplasia verruciformis, 4910 encephalomyocarditis virus RNA cellular DNA synthesis, 4962 type 53 genome internal entry by ribosomes, 1651 type 1 E5 protein cloning and characterization, 4911 5' nontranslated region, 1651 transforming protein, 4515 related to type 30, 4911 protein synthesis, 1651 type 1 E6 gene types 6b and 11 E7 mRNA, 1441 foot-and-mouth disease virus infection mutational analysis, 2340 types 43 and 44 cell heterogeneity, 59 type 1 early and late polyadenylation cloning and DNA sequencing, 2829 human rhinovirus 14, coxsackievirus B3, sites Papillomaviruses and poliovirus chimeras transcriptional termination, 3529 E6 and E7 zinc-binding proteins, 1404 3C substrate specificity, 3444 type 1 growth-arrested transformed cells Papovaviruses Theiler's virus strain GDVII clones DNA BK virus infectious cDNA, 1101 amplification, 2215 origin of DNA replication, 356 Plant RNA viruses type 1 ORFs E6 and E7 BK virus variants pepper mild mottle virus mouse C127 cell transformation, 259 growth efficiency, 3195 variability and evolution, 2198 type 1 transcriptional repressors JC virus isolation Platelet-derived growth factor new cDNAs, 1743 renal and bone marrow transplant pa- simian sarcoma virus mediation by v-sis Papillomavirus, human tients, 4445 baculovirus vector system, 3080 group heterogeneity, 4898 species-specific DNA replication, 5371 expression and purification, 3080 keratinocyte immortalization Parainfluenza virus type 3 Plum pox virus cervical carcinoma association, 159 fusion glycoprotein protease progesterone and glucocorticoid antigenic and functional organization, artificial cleavage site, 2457 response elements 375 Pmv loci long control regions, 3261 fusion protein epitopes mink cell focus-forming murine leukemia type 6b LI ORF monoclonal antibody recognition, 3755 viruses xx SUBJECT INDEX J. VIROL.

recombinant inbred mice, 3810 Polymorphonuclear neutrophilic granulo- sequences, 64 strain distribution patterns, 3810 cytes Prion proteins Poliovirus bovine herpesvirus 1 neuroblastoma cells attenuated and neurovirulent strains neutrophil-derived antiviral protein, protein biosynthesis, 175 human neuroblastoma cell line SH- 1916 Protease SY5Y, 2357 Polyomavirus influenza virus model replication, 2357 AS virus sequence synergism, 2252 chimeric picornaviruses BK virus variant, 901 Protease 3C 3C substrate specificity, 3444 control elements encephalomyocarditis virus defective interfering particles late transcription, 2567 expression in mouse cells, 5013 in vitro construction, 5386 JC virus, BK virus, and simian virus 40 human rhinovirus 14 3'-end sequences hybrid transformation, 863 expression in E. coli, 5037 in vitro transcripts, 467 large T antigen peptide cleavage, 5037 infectivity, 467 DNA-binding specificity, 242 Protein kinase activity guanidine-resistant mutants large T-antigen mutation, 776 herpes simplex virus type 2 ICPIO, 3389 mutations in peptide 2C, 4441 late leader mRNAs phosphorylation and the virus capsid human neuroblastoma cells production and accumulation, 85 poliovirus associated, 3954 attenuated strains, 4034 late mRNA molecules Proviral integration internal ribosome binding 5' noncoding late leader exons, 432 Moloney murine leukemia virus HeLa cell extracts, 441 translational efficiencies, 432 B2mb gene, 2623 RNA translation, 441 late promoter palindromic LTR-LTR junction, 2629 less neurovirulent strains, 5354 deletion analysis, 3634 Pseudorabies virus life cycle in HeLa cells, 43 late region cis-acting sequences Bartha strain gIll defects 5' noncoding mutants DNA synthesis, 4979 envelope protein localization, 250 temperature-sensitive lesion, 847 major capsid protein VPI glycoprotein gIll P68 kinase hydroxyproline, 2881 host cell interactions, 3323 degradation, 2244 middle T antigen glycoprotein gIll gene translational regulation, 2244 70-kDa heat shock protein, 4533 herpes simplex virus type I gC gene, phosphorylation and the virus capsid, middle T antigen-transformed rat cells 4055 3954 p60f'' association, 2343 immediate-early protein binding RNA polymerase myogenesis class II gene promoters, 1869 E. coli expression, 216 gene expression, 4890 latency-associated RNAs, 2908 purification and properties, 216 origin regions release from infected cells, 5475 RNA polymerase mutants, 4866 T-antigen-binding sites, 961 variants type 1/type 2 antigenic hybrid, 5251 rat Fl 11 and mouse NIH 3T3 cells nucleotide sequences, 2690 Poliovirus type 1 transformation, 753 pvt-JlMis-l locus adenovirus major late promoter, 3858 simian virus 40 large T antigen, 5478 Moloney murine leukemia virus inhibition of HeLa cell mRNA synthesis, small T-antigen functions Mlvi-1 locus, 2366 3858 mutational analysis, 2126 Poliovirus type 1 Mahoney target cell DNA damage Rabbit beta-globin mRNA protein degradation killer T cells, 572 herpes simplex virus type I latency-as- two-dimensional gel electrophoresis, TPA and Ha-ras oncogene sociated transcripts, 3844 4729 enhancer elements, 1040 Rabies virus RNA-dependent RNA polymerase VPI major capsid protein, 3168 CVS and AvOl strains phosphorylation of 3DP0', 4563 Potyviruses peripheral nervous system invasion, rRNA synthesis inhibition, 4689 plum pox virus protease 3550 Poliovirus type 1 Sabin artificial cleavage site, 2457 nucleoprotein attenuation phenotype, 1302 tobacco etch virus helper component T-cell epitopes, 2885 genetic variation, 1069 proteinase raf oncogene Poliovirus type 2 autocatalytic processing in E. coli, genetic loci attenuating sequences 4459 susceptibility, 2411 mapping, 1884 Poxviruses rafimyc retrovirus Poliovirus type 2 Lansing capripoxvirus and orthopoxvirus genetic loci 2APro mutant, 5069 genome comparison, 4703 susceptibility, 2411 alpha subunit of eucaryotic initiation fac- cowpox virus early transcription control ras oncogene tor 2 cis-acting elements, 4632 EIA and myc oncogenes phosphorylation, 5069 cowpox virus RNA polymerase cytolytic 3408 second-largest subunit, 1076 susceptibility, Poliovirus type 2 Sabin pp6Ov-src phosphoprotein p53 gene activation neurovirulent variant vaccine Rous sarcoma virus Prague A strain cooperation and transformation, 739 nucleotide sequence, 4949 membrane stability, 291 recombinant sarcoma viruses Poliovirus type 3 Sabin transformation, 291 tumorigenesis, 1377 attenuation pp65 gene RD-1 14 proviruses genetic basis, 1338 human cytomegalovirus long terminal repeats Polymerase chain reaction early-late promoter activation, 1232 enhancer elements, 4234 feline herpesvirus 1 thymidine kinase pr65gag Recombination gene Moloney murine leukemia virus T-cell epitope expression isolation and identification, 3240 assembly and maturation events, 2370 vaccinia virus-lymphocytic choriomen- human immunodeficiency virus type 1 Primate cytomegalovirus ingitis virus, 4311 rev gene function, 4875 assembly protein gene, 669 Reovirus type 1 Lang integrated ecotropic provirus Primate retroviruses L2 and SI genes amplification of flanking DNA, 1924 conserved reverse transcriptase coding intestinal growth, 1188 VOL. 63, 1989 SUBJECT INDEX xxi

Reovirus types 1 and 2 Retroviruslike DNA neutralizing monoclonal antibodies, 3545 high-affinity receptor, 1318 conserved reverse transcriptase coding nonstructural glycoprotein NS28 Reoviruses sequences, 64 receptor activity, 4553 capsid polypeptide c3 Retrovirus-related sequences SAl1 genome segment 11 nonstructural CAT mRNA translation, 2415 murine Y chromosome phosphoprotein, 3974 cotransfected COS cells, 2415 murine leukemia virus, 4043 SAll and rhesus rotaviruses Drosophila S virus viruslike 30S sequences, 4043 passive immunity and reassortment, classification, 1007 rev protein 4525 myocarditic variant 8B, 4840 human immunodeficiency virus SAl 1 surface protein VP4 proteolytic digestion in vivo phosphorylation, 4438 neutralization epitope, 5393 intestinal lumens of neonatal mice, human immunodeficiency virus type 1, simian rotavirus RRV strain 2 4676 1265 virus-specific cytotoxic T variant 8B Reverse transcriptase lymphocytes, 3279 MI gene, 4850 conserved coding sequences virus-specific cytotoxic T lymphocytes myocarditic phenotype, 4850 retroviruslike DNA, 64 intestinal mucosal surface, 3507 Respiratory syncytial virus hepatitis B virus Rous sarcoma virus lA integral membrane glycoprotein, 2019 pol gene, 1019 altered proviruses, 1015 F and G glycoproteins Reverse transcription arachidonic acid metabolism, 2929 antigenic structure, 925 hepatitis B virus myristylated gag protein F glycoprotein neutralization epitopes, P gene expression, 5451 expression in mammalian cells, 4331 2941 Rous sarcoma virus LTR, v-src, LTR 5'-ORF regulation, 4787 G protein glycosylation, 4767 provirus partial activation of p60c-src G protein mutants src mRNA, 1015 chicken embryo fibroblasts, 683 immunogenicity, 411 Rhesus rotavirus pp6(4-src amino-terminal mutations processing, 411 outer capsid protein VP4 membrane stability, 291 surface expression, 411 expression by baculovirus recombi- transformation inactivation, 291 Respiratory syncytial virus, bovine nant, 1661 RNA leader sequence proteins and mRNAs, 833 hemagglutinin, 1661 translation initiation, 4986 Reticuloendotheliosis virus passive immunity and reassortment in RNA splicing envelope glycoprotein vivo, 4525 cis effects, 1669 superinfection interference, 273 Rhinoviruses src gene intron, 1669 new proviral copies human rhinovirus 14 SH-2 domain of pp6Ov-src avian lymphoid cells, 1107 drug-resistant mutants, 2476 host range mutant, 338 replication-defective vectors, 2680 neutralization, 36 transformation, 338 Retroviral proviruses human rhinovirus 14 conformational tumor suppression, 2461 B2mb gene integration, 2623 change v-src gene mutants Retrovirus packaging system adsorption, 2002 linker insertion-deletion mutagenesis, murine leukemia virus human rhinovirus P2 protein 542 Fv-1 sensitive, 2592 host range change, 2396 Rous-associated virus type 1 Retrovirus recombinants human type 14 3C protease RNA polyadenylation and retrovirus Moloney murine leukemia virus expression in E. coli, 5037 replication, 3301 expression, 4431 peptide cleavage, 5037 Retrovirus vectors Ribavirin SAl 1 rotavirus avian leukosis virus lymphocytic choriomeningitis virus genome segment 11 nonstructural phos- packaging cell line, 513 replication block, 1827 phoprotein, 3974 dihydrofolate reductase gene transfer, RNA packaging nonstructural glycoprotein NS28 4857 human immunodeficiency virus type 1, receptor activity, 4553 human c-fpslfes proto-oncogene 4085 passive immunity and reassortment in transforming activity, 5469 RNA polymerase vivo, 4525 internal attachment site influenza virus, 5142 surface protein VP4 murine retrovirus integration, 2844 vaccinia virus ts mutants, 714 neutralization epitope, 5393 Moloney murine leukemia virus cellular map position, 705 Saccharomyces cerevisiae viruses promoters RNA polymerase activity double-stranded RNAs promoter trap, 3227 lymphocytic choriomeningitis virus overlapping genes, 3983 murine amphotropic packaging cells synthesis in vitro, 1938 Scrapie agent cell cycle dependency, 3865 poliovirus 3DIO° mutants, 4866 infectivity of purified mitochondria, 1686 T-lymphocyte infection efficiency, poliovirus expression in E. coli, 216 prion protein biosynthesis 3865 RNA polymerase I neuroblastoma cells, 175 poliovirus type 1 Mahoney Semliki Forest virus murine leukemia virus LTRs transcription 4689 relative inhibition, capsid protein delivery, 2921 expression, 5201 RNA polymerase II E2 envelope epitopes oncogenicity of N-ras oncogene, 3944 vaccinia virus replication, 1540 neutralizing humoral response, 3416 spleen necrosis virus packaging cell lines Rotaviruses membrane proteins helper sequences, 3209 adult diarrhea rotavirus sensitivity to low pH, 4991 Retroviruses structural proteins, 2191 ts22 infection in fetal mice human endogenous retrovirus family, gene expression central nervous system development, 4982 regulation, 2048 4027 protease human and feline strains Sendai virus dimeric aspartic proteinase, 2226 genetic relationship, 1431 glycoprotein folding Rous-associated virus type 1 human strain K8 protein VP4 gene disulfide bonds, 892 RNA polyadenylation and replication, neutralization epitopes, 4101 high-mannose sugars, 892 3301 nucleotide sequence, 4101 infection of protein-malnourished mice, xxii SUBJECT INDEX J. VIROL.

3541 large T-antigen linker insertion mutants Spleen necrosis virus nucleocapsid trans-dominant interference, 4777 packaging cell lines helical states, 2233 large T-antigen variant helper sequences, 3209 protein expression transformed mKS-A cells, 2820 src proteins P/C mRNA, 974 late promoter, 1420 Rous sarcoma virus-induced tumors transcription-replication switch, 1951 late transcripts suppression, 2461 vesicular stomatitis virus glycoproteins requirement for excisable introns, Stromal keratitis phenotypic mixing, 5111 4386 herpes simplex virus SH-SY5Y cells mutant T antigen CD4+ lymphocyte mediation, 769 attenuated and neurovirulent poliovi- p53 binding defect, 3362 Subacute sclerosing panencephalitis ruses plasma membrane-associated large T measles virus matrix gene replication, 2357 antigen hypermutation, 5464 Sigma 3 protein transformed mouse tumor cells, 3926 Subacute sclerosing panencephalitis virus reovirus CAT mRNA translation polarized epithelial cells Biken strain structural defect, 1163 cotransfected COS cells, 2415 virus release, 2278 Surface antigen Simian immunodeficiency virus receptor moieties hepatitis B virus gene expression clone SIVagm3 Vero C1008 cell surfaces, 1095 regulation, 3919 activity in vivo and in vitro, 5119 replication-defective mutant T antigens, animal models, 5119 912 T-antigen binding genetic variability small t-antigen expression polyomavirus origin regions African green monkeys, 1800 monoclonal antibody analysis, 3128 plasmid replication, 961 genital mucosal transmission T-antigen dimers simian virus 40 origin region I, 2901 animal model for heterosexual trans- origin region I binding, 2901 simian virus 40 replication-defective mu- mission of HIV, 4277 T-antigen repression tants, 912 transmembrane protein mutants, 4395 cellular differentiation, 2718 T-antigen expression Simian immunodeficiency virus SIVMAC T-antigen transactivation simian virus 40 antibody-dependent cellular cytotoxicity early and late promoter activity, 383 cellular differentiation, 2718 type- and strain-specific antigens, 3376 HeLa and 293 cells, 383 monoclonal antibody analysis, 3128 env gene products, 1416 UV mutagenesis tat protein transmembrane protein, 4709 mutational hot spot specificity, 4520 human immunodeficiency virus Simian rotavirus RRV strain 2 virion protein synthesis characterization, 1 virus-specific cytotoxic T lymphocytes, effects of 5' ORFs, 3884 human immunodeficiency virus type 1 3279 Sindbis virus mutagenesis, 1181 Simian sarcoma virus 26S cDNA polyprotein processing tax protein v-sis/PDGF-B protein Sf9 cells, 1256 Moloney murine leukemia virus chime- baculovirus vector system, 3080 envelope glycoprotein E2 ras expression and purification, 3080 maturation, 1975 chromatin structure, 3072 Simian virus 5 proteolytic cleavage, 1975 tax-responsive element fusion protein glycoprotein processing human T-cell leukemia virus type I cleavage site deletion mutants, 1293 pathogenic mutations, 1619 signal transduction pathway, 3761 Simian virus 40 group F ts mutants, 1194 T-cell response AP-1 consensus sites, 1737 heat shock proteins rabies virus nucleoprotein, 2885 chimeric DNAs Aedes albopictus cells, 992 Temperature-sensitive mutants JC virus transformation, 2180 nonstructural proteinase processing, brome mosaic virus 2a gene, 5302 class I major histocompatibility proteins 4653 human peripheral blood mononuclear cell surface receptors, 4474 nucleocapsid morphology, 883 cells core origin of replication opal codon preceding nsP4 measles virus infection, 689 topoisomerase I sites, 5175 mutagenesis, 1326 simian virus 40 large T antigen DNA replication RNA encapsidation specificity, 5310 structural regions, 4426 multiple initiation steps, 4181 RNA- temperature-sensitive mutants Sindbis virus nonstructural proteins Epstein-Barr virus hybrid shuttle vector complementation groups A, B, and G, complementation groups A, B, and G, recombination rate, 3837 3142 3142 host range/helper function mutations mapping, 3142 mapping, 3142 viral late gene defects, 5208 subgenomic RNA promoter Sindbis virus tslO3 assembly mutant, hybrid transformation, 863 mutagenesis, 5216 3459 integrated DNA rearrangements tslO3 assembly mutant, 3459 vaccinia virus transformed rodent cells, 165 SL3-3 virus concatemer resolution, 2437 large T antigen enhancer core vaccinia virus recombination, 2030 age-dependent epitope changes, 2352 T-lymphoma cell-specific element, 76 vaccinia virus RNA polymerase, 714 biochemical activities, 2308 long terminal repeats map position, 705 cellular host shock protein, 3961 relative expression, 5201 12-O-Tetradecanoylphorbol-13-acetate nuclear subcompartmentalization, 2308 Small T antigen anti-EBNA-1 induction, 3315 p53 complex modulation, 1310 polyomavirus Epstein-Barr virus MS gene promoter transforming functions, 5459 mutational analysis, 2126 induction, 5062 zinc finger region, 94 simian virus 40 Ha-ras-transformed NIH 3T3 cells large T antigen structural regions monoclonal antibody analysis, 3128 PEBP1 response, 3669 ts mutants, 4426 Solid-matrix-antibody-antigen complexes human papillomavirus type 18 gene large T antigen and Xenopus laevis p53 multiple virus immunization, 1808 expression interaction, 3894 Spleen focus-forming virus herpes simplex virus type 1 activation, large T-antigen expression leukemogenic membrane glycoprotein 555 papillomas of transgenic mice, 790 gpS5 human T-cell leukemia virus type I LTR polyomavirus replication, 5478 processing, 3561 induction, 2987 VOL. 63, 1989 SUBJECT INDEX xxiii

human T-cell leukemia virus type I late gene expression, 1595 M protein p4Otax resolution, 1595 transcription inhibition site, 2841 trans-activator-responsive element, DNA polymerase gene monoclonal antibody-resistant mutants 3234 aphidicolin-resistant mutant, 4060 phenotypic masking, 5030 polyomavirus enhancer elements DNA polymerase mutants, 841 mouse alpha and beta interferons Ha-ras oncogene, 1040 DNA-dependent ATPase I natural autoantibodies, 955 Theiler's murine encephalomyelitis virus intermediate and late gene expression, population heterogeneity, 2072 DA strain 3999 RNA polymerase error frequencies, 2063 infectious cDNA clones, 5492 foreign genes Sendai virus glycoproteins polyprotein processing, 5344 cloning and expression, 3829 phenotypic mixing, 51 1 1 neutralization escape mutants, 4469 host range selection system, 3829 small nuclear ribonucleoprotein matura- neutralizing monoclonal antibody host range gene protein tion, 4172 athymic mouse survival, 2081 orthopoxvirus conservation, 1814 strains Orsay and San Juan G proteins Theiler's virus synthetic peptide, 1814 glycosylation requirement, 3801 neutralization-resistant variant late transcription factors, 4224 intracellular transport, 3801 mouse central nervous system, 1505 membrane protein point mutation T-cell clones strain GDVIII clones plaque size phenotype, 4507 Trojan horse lymphocytes, 4157 infectious cDNA, 1101 plasma serine protease inhibitor super- Vimentin Thymidine kinase expression family, 600 Epstein-Barr virus latent membrane pro- herpes simplex virus Spl-binding sites, protein acylation, 4285 tein, 4051 4088 resolution of cocatemer junction human B-cell lines, 4079 herpes simplex virus type 1 latency-as- nucleotide sequence, 4354 Viral serpins sociated transcript, 2861 RNA polymerase vaccinia virus proteins Tick-borne encephalitis virus ts mutant phenotype, 714 plasma serine protease inhibitor super- envelope protein E RNA polymerase II family, 600 antigenic structure, 564 replication, 1540 Virus-associated RNAs Tobacco etch virus RNA polymerase ts mutants adenovirus type 5 helper component proteinase map position, 705 temperature-dependent expression, autocatalytic processing in E. coli, temperature-sensitive mutants 5445 4459 homologous recombination, 2030 Virus-associated RNAs I and II Topoisomerase I ppp(A2'p)nA-dependent RNase, 948 adenovirus simian virus 40 core origin of replica- ts mutants defective in concatemer reso- functional dissection, 3423 tion, 5175 lution, 2437 Visna virus trans-Activation-responsive element Vaccinia virus recombinants F(ab')2 fragments human immunodeficiency virus type 1 bovine herpesvirus 1 expression infectivity in macrophages, 1811 sequence specificity, 5501 glycoproteins gI and gIIl, 2159 lentivirus replication, 1811 Transgenic mice bovine parainfluenza 3 virus envelope interference, coinfections, intertypic vi- lymphotropic papovavirus-induced neo- protein genes rus enhancement plasia, 2204 syncytium formation, 3661 caprine arthritis-encephalitis virus, simian virus 40 T-antigen expression, dengue virus structural proteins 4682 790 immunization, 2853 long terminal repeat Trojan horse lymphocytes equine herpesvirus 1 glycoprotein gpl3 mutational analysis, 3001 vesicular stomatitis virus-specific T-cell gene expression, 4189 LTR and gene expression clones, 4157 human immunodeficiency virus type 1 transgenic mice, 1891 Tumor necrosis factor gag and pol gene expression, 1451 Vmw65 mutant herpes simplex virus type 1 blockage plaque size phenotype herpes simplex virus type 1, 2260 synergism with interferon, 1354 selectable marker, 997 Vmw65 protein human immunodeficiency virus type 1 T-cell epitope expression herpes simplex virus type 1 induction via CD4 receptor, 4404 engineered vaccine, 4311 octamer-binding factor interaction, human immunodeficiency virus-infected lymphocytic choriomeningitis virus, 1641 cells 4311 Vmwl 10 protein cytocidal effect, 2504 Varicella-zoster virus herpes simplex virus type 1 Tumor-specific transplantation antigen gene 47 latent infection reactivation, 3513 p53-plus-ras-transformed cells homology with herpes simplex and v-myc oncogene cross-reactive activity, 5440 Epstein-Barr viruses, 450 avian retrovirus FH3, 5092 Turnip yellow mosaic virus new protein kinase-related gene, 450 EIA and ras oncogenes 150K protein glycoprotein gpl phosphorylation cytolytic susceptibility, 3408 proteolytic origin, 5153 mammalian casein kinases, 3912 terminal differentiation Type C retroviruses glycoprotein oligosaccharides infected erythroid cells, 1489 Gv-l-responsive endogenous loci phosphorylation, 4264 VPI capsid protein truncated gag products, 4136 peripheral blood mononuclear cells polyomavirus UAA and UGA termination codons in situ hybridization, 2392 hydroxyproline, 2881 suppression, 2870 rat sensory neuron infection, 3155 polyomavirus synthesis, 3168 v-cbl oncogene VP4 capsid protein Vaccine strains homologous murine loci, 3678 human rotavirus K8 strain attenuated poliovirus strains Vesicular stomatitis virus neutralization epitopes, 4101 human neuroblastoma cells, 4034 1:1 N-NS protein complex nucleotide sequence, 4101 Vaccinia virus genome replication, 3852 vpr gene capped poly(A) leaders glycoprotein mutant human immunodeficiency virus type 1 late mRNA, 226 virion assembly, 3569 mutational analysis, 4110 cis and trans elements, 2726 glycoprotein oligomerization vpu protein DNA concatemer junctions trimer formation, 5328 human immunodeficiency virus type 1 xxiv SUBJECT INDEX J. VIROL.

molecular and biochemical analyses, v-src-induced cell susceptibility, 4797 murine and avian fibroblasts, 4665 3784 SH-2 domain of pp6Ov-src nucleic acids, 1612 v-raf oncogene host range mutant, 338 plus-strand DNA priming, 1907 terminal differentiation transformation, 338 infected erythroid cells, 1489 X gene product v-rel oncogene West Nile virus hepatitis B virus gene transactivation, reticuloendotheliosis virus membrane proteins 4019 proviral copies, 1107 cell-associated virus, 2521 v-sis oncogene proteolytic cleavage, 2521 Yellow fever virus simian sarcoma virus PDGF-B protein WIN 52084 baculovirus vector system, 3080 human rhinovirus 14 polyprotein processing, 4199 expression and purification, 3080 drug-resistant mutants, 2476 v-src oncogene Woodchuck hepatitis virus Zinc finger region minute virus of mice, prototype strain kinetic patterns, 1360 simian virus 40 large T antigen, 94 1990 APPLICATION FOR STUDENT MEMBERSHIP IN THE AMERICAN SOCIETY FOR MICROBIOLOGY 1325 Massachusetts Avenue, NW * Washington, D.C 20005 * (202) 737-3600 * FAX (202) 737-0367

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