2. DISTRIBUTE: the Cards, and Make Sure Everyone Has a Pen

Instructions: 1. PREPARE: Print out different BINGO cards for each participant. If you have many people, you can create additional cards by moving the answers around on within the boxes. Or you can have several winners at the same time. Here, we have included 4 cards. Only the “leader” should have the Question and Answer sheet. 2. DISTRIBUTE: The cards, and make sure everyone has a pen. 3. PLAY: The leader should read out questions in a random order. Participants fill in the boxes with the appropriate answers. 4. WIN! Participants win by getting four filled in boxes in a row – diagonal, vertical, or horizontal. Quite nice to provide a token present (button, pen, etc.) to the winners.

Questions Answers Why do women, in particular, need Gender inequality, poverty, biological susceptibility microbicides? and violence against women have caused HIV to become more and more a women’s epidemic. What are microbicides? Substances that can lower a person’s risk HIV and other STI’s when used in the vagina, or rectum. What forms will microbicides take? Gels and creams and in the future sponges, vaginal rings, gels with barrier devices. What is one key benefit of microbicides for people who can not They will be able to be used without a partner’s tell their partner that they are using awareness if necessary. microbicides, out of fear of abandonment or violence? Will HIV be the only virus that No, microbicides may also reduce the risk of other microbicides will work against? STIs. How might microbicides be Some products may be able to reduce the risk of beneficial for HIV positive people, in re-infection with other HIV strains. particular? What is one way that might help HIV Some products might be non-contraceptive so an positive women in particular? HIV-positive woman could conceive without putting her male partner at risk if he is HIV- negative. Why is it more complicated to Partly because the rectal tissue is more fragile than develop rectal microbicides? the tissue lining of most of the vagina Who needs rectal microbicides? Many people (both women and men), for anal sex. How effective will the first 40-60% effective microbicides probably be? Once the first microbicides are on the Use a male or female condom every time you have market what is one message that sex, if you absolutely can not, use a microbicide. should be put out about them?

Global Campaign for Microbicides. June 2007. Reproduction encouraged. For info contact: [email protected] Updates available at: www.global-campaign.org/download.htm Questions Answers If vaginal microbicides are going to Vaginal microbicides give women a chance to be only partially effective what good increase the consistency of the protection they get, is that to women? and hopefully thereby reduce their overall HIV risk. A condom has zero effectiveness if the male partner does not put it on. What are phase 1 and 2 trials? They are safety trials. What is another prevention tool Pre-exposure prophylaxis (PrEP) currently being researched that might also help reduce transmission of HIV? What is one of the ways how By preventing the HIV virus from fusing with the microbicides actually prevent a target cells of the person. person from becoming HIV infected? Why are Phase 3 trials only These trials measure a product’s effectiveness and happening in developing countries— so are done in populations where the prevalence of in Africa in particular? HIV is very high because that is an easy way to measure how well the product reduces infection risk When will we know how effective Between 2008-2009 we will be getting the data on one of these products actually is? the effectiveness of Carraguard. What is one reason that big Microbicides are considered a “public health good” pharmaceutical companies are not but are perceived to have little profitability. investing in microbicides research? Why isn’t microbicide research Due to lack of money trials keep being delayed. moving forward as fast as it could? More funding is needed! What are some of the ways that a They might inactivate the virus, strengthen the microbicide may work? body’s normal defenses, block viral entry, or stop viral replication. What is the Global Campaign? A coalition of organizations working to accelerate access to new prevention technologies What is the potential public health If a 60% effective product is introduced in 73 low- impact of microbicides? income countries, it could avert 2.5 million HIV infections among women, children and men.

Global Campaign for Microbicides. June 2007. Reproduction encouraged. For info contact: [email protected] Updates available at: www.global-campaign.org/download.htm Gender inequality, poverty, Between 2008-2009 we will Microbicides are considered Due to lack of money trials biological susceptibility and be getting the data on the a “public health good” but keep being delayed. violence against women effectiveness of are perceived to have little More funding is needed! have caused HIV to Carraguard. profitability. become more and more a women’s epidemic.

A coalition of organizations Some products might be They will be able to be They might inactivate the working to accelerate non-contraceptive so an used without a partner’s virus, strengthen the access to new prevention HIV-positive woman could awareness if necessary. body’s normal defenses, technologies conceive without putting block viral entry, or stop her male partner at risk if viral replication. he is HIV-negative.

Gels and creams and in the Some products may be By preventing the HIV virus 40-60% effective future sponges, vaginal able to reduce the risk of from fusing with target rings, gels with barrier re-infection with other HIV cells of the person. devices. strains.

Use a male or female They are safety trials Partly because the rectal No, microbicides may also condom every time you tissue is more fragile than reduce the risk of other have sex, if you absolutely the tissue lining of most of STIs. can not, use a microbicide. the vagina.

Global Campaign for Microbicides. June 2007. Reproduction encouraged. For info contact: [email protected] Updates available at: www.global-campaign.org/download.htm If a 60% effective product is These trials measure a Vaginal microbicides give A coalition of organizations introduced in 73 low-income product’s effectiveness and women a chance to increase working to accelerate access countries, it could avert 2.5 so are done in populations the consistency of the to new prevention million HIV infections among where the prevalence of HIV protection they get, and technologies women, children and men is very high because that is hopefully thereby reduce over 3 years. an easy way to measure how their overall HIV risk. A well the product reduces condom has zero infection risk. effectiveness if the male partner does not put it on.

Due to lack of money trials Many people They might inactivate the Between 2008-2009 we will keep being delayed. (both women and men), virus, strengthen the body’s be getting the data on the More funding is needed! for anal sex. normal defenses, block viral effectiveness of Carraguard. entry, or stop viral replication.

Gels and creams and in the Some products may be able By preventing the HIV virus They will be able to be used future sponges, vaginal to reduce the risk of re- from fusing with target cells without a partner’s rings, gels with barrier infection with other HIV of the person. awareness if necessary. devices. strains.

Use a male or female They are safety trials Partly because the rectal Microbicides are considered a condom every time you have tissue is more fragile that the “public health good” but are sex, if you absolutely can tissue lining most of the perceived to have little not, use a microbicide. vagina. profitability.

Global Campaign for Microbicides. June 2007. Reproduction encouraged. For info contact: [email protected] Updates available at: www.global-campaign.org/download.htm Microbicides are considered a Some products may be able Partly because the rectal No, microbicides may also “public health good” but are to reduce the risk of re- tissue is more fragile than reduce the risk of other STIs. perceived to have little infection with other HIV the tissue lining of most of profitability. strains. the vagina.

They will be able to be used They are safety trials Use a male or female Gels and creams and in the without a partner’s condom every time you have future sponges, vaginal rings, awareness if necessary. sex, if you absolutely can gels with barrier devices. not, use a microbicide.

Gender inequality, poverty, These trials measure a Vaginal microbicides give They might inactivate the biological susceptibility and product’s effectiveness and women a chance to increase virus, strengthen the body’s violence against women have so are done in populations the consistency of the normal defenses, block viral caused HIV to become more where the prevalence of HIV protection they get, and entry, or stop viral and more a women’s is very high because that is hopefully thereby reduce replication. epidemic. an easy way to measure how their overall HIV risk. A well the product reduces condom has zero infection risk. effectiveness if the male partner does not put it on.

40-60% effective Substances that can prevent Pre-exposure prophylaxis By preventing the HIV virus HIV and other STI’s when (PrEP) from fusing with target cells used in the vagina, or of the person. rectum.

Global Campaign for Microbicides. June 2007. Reproduction encouraged. For info contact: [email protected] Updates available at: www.global-campaign.org/download.htm A coalition of organizations These trials measure a By preventing the HIV These trials measure a working to accelerate access to product’s effectiveness virus from fusing with product’s effectiveness new prevention technologies and so are done in target cells of the person. and so are done in populations where the populations where the prevalence of HIV is prevalence of HIV is very high because that very high because that is an easy way to is an easy way to measure how well the measure how well the product reduces product reduces infection risk. infection risk.

They might inactivate the virus, Substances that can Partly because the rectal No, microbicides may strengthen the body’s normal prevent HIV and other tissue is more fragile than also reduce the risk of defenses, block viral entry, or STI’s when used in the the tissue lining of most of other STIs. stop viral replication. vagina, or rectum. the vagina.

Due to lack of money trials Microbicides are If a 60% effective product Some products may be keep being delayed. considered a “public is introduced in 73 low- able to reduce the risk More funding is needed! health good” but are income countries, it could of re-infection with perceived to have little avert 2.5 million HIV other HIV strains. profitability. infections among women, children and men over 3 years.

Many people (both women and 40-60% effective They are safety trials Gels and creams and in men), for anal sex. the future sponges, vaginal rings, gels with barrier devices.

Global Campaign for Microbicides. June 2007. Reproduction encouraged. For info contact: [email protected] Updates available at: www.global-campaign.org/download.htm