Supplementary File Information
Total Page：16
File Type：pdf, Size：1020Kb
Supplementary file information
Article name:
Assessment of association of rs2200733 at 4q25 with atrial fibrillation and ischemic stroke in a
Chinese Han population
Journal name:
Human Genetics
Authors’ names:
Lisong Shi · Cong Li · Chuchu Wang · Yunlong Xia · Gang Wu · Fan Wang · Chengqi Xu ·
Pengyun Wang · Xiuchun Li · Dan Wang · Xin Xiong · Ying Bai · Yanzong Yang · Lianjun Gao ·
Bo Yang · Mugen Liu · Jingyu Liu · Xiang Ren · Binbin Wang · Xu Ma · Qiutang Zeng · Xin Tu ·
Qing Kenneth Wang
Corresponding address:
Dr. Qing Kenneth Wang ([email protected]) or Dr. Xin Tu ([email protected]),
Key Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and
Technology and Center for Human Genome Research, Huazhong University of Science and
Technology, Luoyu Road 1037, Wuhan, China 430074. Telephone: 86-27-87792649 Fax: 86-27-
87794549 Supplementary Table 1 Genotypic distribution of SNP rs2200733 genotypes in the GeneID study
population Characteristic Genotype (case) Genotype (control) (case/control) T/T T/C C/C T/T T/C C/C HWE Pa n
o Total 171 153 59 212 432 207 0.655 i t a l
l Male 108 94 35 139 292 130 0.328 i r b
i Female 63 59 24 73 140 77 0.559 F
l b
a Age <60 92 75 28 101 214 111 0.914 i r t Ageb ≥60 79 78 31 111 218 96 0.576 A lone AF 65 47 13 212 432 207 0.655 other AF 106 106 46 AF with stroke 25 25 2 212 432 207 0.655 AF w/o stroke 146 128 57 AF with HT 62 60 26 120 247 115 0.583 AF w/o HT 109 93 33 92 185 92 0.958 AF with CAD 25 33 10 26 50 20 0.654 AF w/o CAD 146 120 49 186 382 187 0.743
e Total 200 405 206 189 325 174 0.151 k o r
t Male 107 242 127 121 205 129 0.237 S
c
i Female 93 163 79 68 120 65 0.415 m e Ageb<60 64 165 94 105 168 88 0.202 h c
s b I Age >=60 136 240 112 84 157 86 0.473 HWE, Hardy-Weinberg equilibrium; AF, atrial fibrillation; HT, hypertension; CAD, coronary artery disease aHWE P<0.05 denotes the deviation from Hardy-Weinberg Equilibrium bAge for the case group refers to as the age at diagnosis of AF; Age for the control group refers to as the age at which the study subjects were enrolled into the study.