<p>Supplementary file information</p><p>Article name:</p><p>Assessment of association of rs2200733 at 4q25 with atrial fibrillation and ischemic stroke in a</p><p>Chinese Han population</p><p>Journal name:</p><p>Human Genetics</p><p>Authors’ names:</p><p>Lisong Shi · Cong Li · Chuchu Wang · Yunlong Xia · Gang Wu · Fan Wang · Chengqi Xu ·</p><p>Pengyun Wang · Xiuchun Li · Dan Wang · Xin Xiong · Ying Bai · Yanzong Yang · Lianjun Gao ·</p><p>Bo Yang · Mugen Liu · Jingyu Liu · Xiang Ren · Binbin Wang · Xu Ma · Qiutang Zeng · Xin Tu ·</p><p>Qing Kenneth Wang</p><p>Corresponding address: </p><p>Dr. Qing Kenneth Wang ([email protected]) or Dr. Xin Tu ([email protected]), </p><p>Key Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and</p><p>Technology and Center for Human Genome Research, Huazhong University of Science and</p><p>Technology, Luoyu Road 1037, Wuhan, China 430074. Telephone: 86-27-87792649 Fax: 86-27-</p><p>87794549 Supplementary Table 1 Genotypic distribution of SNP rs2200733 genotypes in the GeneID study</p><p> population Characteristic Genotype (case) Genotype (control) (case/control) T/T T/C C/C T/T T/C C/C HWE Pa n</p><p> o Total 171 153 59 212 432 207 0.655 i t a l</p><p> l Male 108 94 35 139 292 130 0.328 i r b</p><p> i Female 63 59 24 73 140 77 0.559 F</p><p> l b</p><p> a Age <60 92 75 28 101 214 111 0.914 i r t Ageb ≥60 79 78 31 111 218 96 0.576 A lone AF 65 47 13 212 432 207 0.655 other AF 106 106 46 AF with stroke 25 25 2 212 432 207 0.655 AF w/o stroke 146 128 57 AF with HT 62 60 26 120 247 115 0.583 AF w/o HT 109 93 33 92 185 92 0.958 AF with CAD 25 33 10 26 50 20 0.654 AF w/o CAD 146 120 49 186 382 187 0.743</p><p> e Total 200 405 206 189 325 174 0.151 k o r</p><p> t Male 107 242 127 121 205 129 0.237 S</p><p> c</p><p> i Female 93 163 79 68 120 65 0.415 m e Ageb<60 64 165 94 105 168 88 0.202 h c</p><p> s b I Age >=60 136 240 112 84 157 86 0.473 HWE, Hardy-Weinberg equilibrium; AF, atrial fibrillation; HT, hypertension; CAD, coronary artery disease aHWE P<0.05 denotes the deviation from Hardy-Weinberg Equilibrium bAge for the case group refers to as the age at diagnosis of AF; Age for the control group refers to as the age at which the study subjects were enrolled into the study.</p>