Table 3. HLA Haplotypes in Alabama Subjects.1
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Table 3. HLA Haplotypes in Alabama Subjects.1
HLA-A HLA-B Hemochromatosis Probands Controls (1,210 Significant values
(236 chromosomes) chromosomes) of p 01 07 0.0042 0.0124
08 0.0720 0.0669
14 0.0042 0.0017
37 0.0042 0.0050
44 0.0042 0.0091
57 0.0085 0.0066
60 0.0085 0 0.0265
62 0.0085 0.0050
70 0.0042 0
02 07 0.0127 0.0331
08 0.0127 0.0083
14 0.0085 0
15 0.0042 0
18 0.0042 0.0050
27 0.0042 0.0083
35 0.0042 0.0083
37 0.0042 0
39 0.0169 0.0033 0.0282
44 0.0508 0.0603
48 0.0042 0
51 0.0085 0.0132
56 0.0085 0.0017
60 0.0127 0.0083
62 0.0085 0 0.0265
03 07 0.2966 0.0331 < 0.0001
13 0.0169 0 0.0007
14 0.0847 0.0083 < 0.0001
15 0.0085 0 0.0265 17 0.0042 0
27 0.0085 0 0.0265
35 0.0127 0 0.0043
37 0.0042 0
44 0.0339 0 < 0.0001
47 0.0127 0 0.0043
51 0.0085 0.0017
57 0.0169 0 0.0007
62 0.0212 0.0099
72 0.0042 0
11 07 0.0085 0.0066
14 0.0042 0
18 0.0042 0.0017
27 0.0042 0
35 0.0085 0.0066
37 0.0042 0
40 0.0042 0.0017
51 0.0042 0.0033
60 0.0042 0.0017
23 44 0.0085 0.0033
24 07 0.0085 0.0050
44 0.0085 0.0083
51 0.0042 0.0017
55 0.0042 0
56 0.0042 0
25 18 0.0042 0.0033
35 0.0042 0
39 0.0042 0
44 0.0042 0
56 0.0042 0
60 0.0042 0
28 08 0.0042 0 14 0.0042 0.0033
55 0.0042 0
44 0.0127 0.0066
29 44 0.0127 0.0099
30 60 0.0042 0
31 08 0.0042 0
40 0.0042 0.0033
60 0.0042 0.0017
32 35 0.0042 0
38 0.0042 0
44 0.0042 0
33 14 0.0042 0.0050
1These data represent 118 unrelated white C282Y homozygous hemochromatosis probands (= 236 chromosomes) and 605 white persons (= 1,210 chromosomes) who underwent haplotype analysis for paternity testing. All subjects were residents of
Alabama. All haplotypes could be detected with DNA-based and serologic methods with the exception of haplotypes containing B*70 and B*72 that were not detected by serologic methods.