Nanostructured Biomaterials for Medical and Biological Applications

Jackie Y. Ying*

31 Biopolis Way, The Nanos, Singapore 138669 Institute of Bioengineering and Nanotechnology Singapore [email protected]

Nanostructured materials have been developed for various medical and biological applications. They have been designed as stimuli-responsive drug delivery systems and sustained protein delivery systems. Nanocomposite systems have also been derived to provide simultaneous drug delivery and bioimaging functions as theranostic systems. Micellar nanocomplexes have been synthesized with green tea-based ingredients as unique carrier materials that offer synergistic therapeutic effects with the drugs to be delivered.

In addition, nanostructure processing has been employed in creating synthetic cell culture substrates for the expansion and controlled differentiation of stem cells. Nanostructured scaffolds have also been obtained for cell and tissue engineering. Unique hydrogels have been developed for antifouling biomaterial applications.

References

Chung, J. E.; Tan S.; Gao S. J.; Yongvongsoontorn N.; Kim S. H.; Lee J. H.; Choi H. S.; Yano H.; Zhuo L.; Kurisawa M.; Ying J. Y. Nature Nanotech. 2014, 9, 907-912.

Wang Y.; Ibrahim N. L.; Jiang J.; Gao S.; Erathodiyil N.; Ying J. Y. J. Control. Release 2013, 169, 211-219.

8th International Nanomedicine Conference, Sydney, Australia, July 3‒5, 2017. Plenary Lecture.