White Shark Genome Reveals Ancient Elasmobranch Adaptations Associated with Wound Healing and the Maintenance of Genome Stability
White shark genome reveals ancient elasmobranch adaptations associated with wound healing and the maintenance of genome stability Nicholas J. Marraa,b,c,1,2, Michael J. Stanhopec,1,3,4, Nathaniel K. Jued, Minghui Wange, Qi Sune, Paulina Pavinski Bitarc, Vincent P. Richardsf, Aleksey Komissarovg, Mike Raykoh, Sergey Kliverg, Bryce J. Stanhopec, Chuck Winkleri, Stephen J. O’Brieng,j,4, Agostinho Antunesk,l, Salvador Jorgensenm, and Mahmood S. Shivjia,b,3,4 aSave Our Seas Shark Research Center, Nova Southeastern University, Dania Beach, FL 33004; bGuy Harvey Research Institute, Nova Southeastern University, Dania Beach, FL 33004; cPopulation Medicine and Diagnostic Sciences, Cornell College of Veterinary Medicine, Cornell University, Ithaca, NY 14853; dSchool of Natural Sciences, California State University, Seaside, CA 93955; eInstitute of Biotechnology, Bioinformatics Facility, Cornell University, Ithaca, NY 14853; fDepartment of Biological Sciences, Clemson University, Clemson, SC 29634; gTheodosius Dobzhansky Center for Genome Bioinformatics, St. Petersburg State University, 199004 St. Petersburg, Russia; hCenter for Algorithmic Biotechnology, Institute for Translational Biomedicine, St. Petersburg State University, 199004 St. Petersburg, Russia; iAquatic Research Consultants, San Pedro, CA 90732; jGuy Harvey Oceanographic Center, Halmos College of Natural Sciences and Oceanography, Nova Southeastern University, Ft. Lauderdale, FL 33004; kInterdisciplinary Centre of Marine and Environmental Research, University of Porto, 4450–208 Porto, Portugal; lDepartment of Biology, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal; and mConservation Research Department, Monterey Bay Aquarium, Monterey, CA 93940 Contributed by Stephen J. O’Brien, December 17, 2018 (sent for review November 19, 2018; reviewed by Brian W. Bowen, Christophe J. Douady, and Ben F. Koop) The white shark (Carcharodon carcharias; Chondrichthyes, Elasmo- branchii) is one of the most publicly recognized marine animals.
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