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Amazing Urps! 400 Science Enthusiasts at a Monthly Event in Brooklyn Latest Tomato Genetics Research to Big Problems Like World Called the Secret Science Club HARBOR Cold Spring Harbor, NY 11724 TRANSCRIPT Don’t think science is for the masses? Download the CSHL Harbor Transcript iPad app to view extras for this issue! See CSHL scientists onstage at the Secret Science Club Visit www.cshl.edu to sign up for our monthly email newsletter. Come for a drink, but stay for the science and mingle with Lippman took to the stage earlier in the year, linking his Amazing URPs! 400 science enthusiasts at a monthly event in Brooklyn latest tomato genetics research to big problems like world called the Secret Science Club. CSHL scientists are hunger. See their appearances for yourself on YouTube regular headliners. This summer, Assistant Professor and watch for upcoming CSHL Secret Science Club CSHL’s launch pad for gifted undergrads Anne Churchland wowed the crowds discussing how the appearances at the Bell House in 2014. brain makes complex decisions. Associate Professor Zach VOLUME 33 • ISSUE 2 • 2013 PRESIDENT’S MESSAGE Harbor Transcript Volume 33, Issue 2, 2013 To be a scientist requires passion and dedication to a way of working called the scientific method. It entails asking Harbor Transcript is published questions in a manner that involves embracing new ideas by the Department of Public Affairs of Cold Spring Harbor and abandoning dogma. It calls for careful strategic think- Laboratory. ing even before experiments begin. Scientists, to be pro- ductive, need to develop a path for their research that will Public Affairs reveal coherence as it unfolds—step by step, over periods One Bungtown Road Cold Spring Harbor, NY 11724 usually measured in many years, not months or days. 516.367.8455 Today, research institutions like CSHL all over the coun- [email protected] try find themselves operating in an environment of short-term decision making www.cshl.edu due to an uncertain funding environment. Decisions are being made on the fly With the installation of a commemorative engraved glass wall, we recognize the generous contributions of the donors who made possible because Congress and the President have failed to agree on a national budget V.P. Communications: the largest expansion in the history of the Cold Spring Harbor Laboratory. The six Hillside Laboratory buildings opened in 2009 allow now for 5 years running. Moreover, in the last year vacillation has triggered Dagnia Zeidlickis CSHL to further its research and education mission well into the 21st century. automatic, indiscriminate, across-the-board cuts in everything the government Managing Editor: Phil Renna supports, including scientific research that is a key economic driver. Science Writers: Edward Brydon Such indecision comes on top of an unprecedented decade of declining NIH Peter Tarr Cold Spring Harbor Laboratory Board of Trustees CSHL Association budgets. The current malaise is also not good for our nation insofar as it results Design & Layout: Margot Bennett in widespread low morale, particularly among the new generation of American Officers Scientific Trustees CSHL Association comprises Honorary Directors Photography: Jamie C. Nicholls Tania A. Baker, Ph.D. some 1000 neighbors and Mary D. Lindsay scientists who may not have a career in science. Eventually a lack of progress in Philip Renna: front cover, Chairman Cornelia Isabella Bargmann, Ph.D. friends of the Laboratory who Anne R. Meier science and medicine will imperil American world leadership. inside back cover; Robert D. Lindsay Michael Botchan, Ph.D. contribute to the Annual Fund, an Cathy Cyphers Soref Charles Camarda: Vice-Chairman Charles L. Sawyers, M.D. essential source of unrestricted Pearl F. Staller inside front cover; The situation is serious and calls for resolution at the national level. In the Marilyn H. Simons, Ph.D. Samuel L. Stanley, Jr., M.D. support for outstanding young Courtesy Huang lab: Vice-Chairman Bruce Stillman, Ph.D. scientists. Association members Directors meantime, Cold Spring Harbor Laboratory’s position remains comparatively 1, 10, 11, 12; Leo A. Guthart get to know CSHL scientists at Elizabeth Ainslie strong, in part because of the strength and foresight of our philanthropic bene- Courtesy Martienssen: 1, 3; Treasurer Individual Trustees lectures, concerts, dinners and Hans E.R. Bosch Courtesy Malaysian Palm Paul J. Taubman factors. There are organizational reasons for our strength, too. We have a long David Boies other social events that support Michele Munn Celestino Oil Board: 3; Secretary history of attracting the best and the brightest who are strong competitors in Charles I. Cogut the Laboratory. Membership Edward A. Chernoff Edward Brydon: 1, 7; Bruce Stillman, Ph.D. Jacob Goldfield levels start at $100 per year. Susan A. Cohen the hunt for very limited federal grants. It is researchers like Professors Greg Constance Brukin: President & CEO Leo A. Guthart For more information please Maria de Lesseps Hannon and Josh Huang, highlighted in the pages of this magazine, who have 3, 4, 10, 14; W. Dillaway Ayres, Jr. Jeffrey E. Kelter contact Karen Orzel, Nelson DeMille Courtesy CSHL Archives: 5; Chief Operating Officer dedicated themselves to the highest standards and have achieved extraordinary Laurie J. Landeau, V.M.D. Director, Annual Giving Carolyn Gulotta Courtesy Jackson lab: 8–9; Thomas D. Lehrman and Donor Relations, Nancy Lippman Israeli, M.D. results. These investigators are role models for up-and-coming scientists like Dr. Henry Markram (EPFL, Honorary Trustees Robert D. Lindsay at 516.367.6886 or Joel J. Kassimir, M.D. the very talented undergraduate student you see on our cover, who worked at Switzerland): 10; Bayard Clarkson, M.D. Robert W. Lourie, Ph.D. [email protected]. Kassahun Kebede CSHL this summer. Patrick McMullan: 13; Norris W. Darrell Howard L. Morgan, Ph.D. Virginia Knott Gina Motisi: 16; Charles F. Dolan Jamie C. Nicholls Officers Laureen Stanton Knutsen Chris Gazzo: back cover As a nation we must make sure that today’s undergraduates have the same Helen Ann Dolan Louise M. Parent Sandra Tytel, Suzanne Leeds Lola N. Grace John C. Phelan President Timothy Q. O’Neill opportunities as those of us who have had the good fortune to make major On the cover: David H. Koch Thomas C. Quick Frank O’Keefe, Olga Pharr contributions to American science. Only by having a long-term vision will our Alexis Tchaconas, a senior Mary D. Lindsay William S. Robertson Vice-President Whitney F. Posillico at Columbia University, was society continue to be a pioneer in science. David L. Luke III George Sard W. Fifield Whitman, Charles S. Ryan, J.D., Ph.D. one of 27 gifted college Nancy Abeles Marks Thomas A. Saunders III Vice-President Tracey DeMatteis Serko students who took part in Eduardo G. Mestre Marilyn H. Simons, Ph.D. James A. Woods, Hope Geier Smith the Undergraduate Research William R. Miller Dinakar Singh Treasurer Debra Parmet Sondock Program in summer 2013. Alan Seligson James M. Stone, Ph.D. Charles B. Goodwin, M.D., Heather Lane Spehr Her study of autism, James D. Watson, Ph.D. Paul J. Taubman Secretary Peter S. Tilles performed in the lab of Henry Wendt III Edward Travaglianti Lara S. Trafelet Professor Mike Wigler, Sandra Tytel Marjorie J. van de Stouwe, M.D. was motivated by a family Roy J. Zuckerberg connection to the disorder. HARBOR TRANSCRIPT • ISSUE 2 • 2013 HARBOR TRANSCRIPT Postdoc Christine Iok In Chio named a Damon Runyon Fellow Christine Iok In Chio, Ph.D., a postdoctoral researcher, has been named a Damon Runyon Fellow. Dr. Chio works in the Volume 33 • Issue 2 • 2013 laboratory of Dr. David Tuveson, Deputy Director of Research at CSHL’s Cancer Center, Director of the Lustgarten Foundation FEATURES Notre Dame establishes DNA Learning Center Pancreatic Research Laboratory at CSHL and Director of Cold Spring Harbor Laboratory has partnered with the Research for the Lustgarten Foundation. Dr. Chio’s research University of Notre Dame in a licensing agreement that 2 Holding the line on rainforest loss shares the original mission of our DNA Learning Center Discovery of the genetic key to boosting the yield of oil (DNALC). “We encourage the spread of hands-on science palm trees has roots at CSHL centers devoted to modern biology education and preparing students and families to thrive in the gene age,” said David 4 My amazing ‘URP’ summer Micklos, the Executive Director of the CSHL center dedi- A Columbia University undergrad writes about cated to public education. The center in Southbend, Indiana, her summer studying autism in the Wigler Lab will fulfill the vision of Notre Dame benefactors John and Heidi Passarelli, who saw firsthand how the DNALC was 7 What mad pursuit! providing a superb participatory genetics education to chil- A sporting event unique to CSHL: the annual plate race dren across the New York metro area. Through involvement 10 in the DNALC Corporate Advisory Board, the Passarellis 8 One experiment initiated the link to the University of Notre Dame. Celebrat- A mutant ear of corn provides insights about plant ing its 25-year anniversary, CSHL’s DNA Learning Center has Each cortical chandelier cell has veto power over the signal of growth and crop yield successfully collaborated with public school districts, private hundreds of excitatory neurons schools, departments of education, and universities, including 10 Research Profile: Z. Josh Huang the Republic of Singapore and Clemson University. Exploring the cerebral cortex is like navigating the jungle. Huang’s genetic tools are like a GPS system. FACULTY & FRIENDS President’s Council on infectious disease CSHL alumni headlined this year’s intellectual retreat 13 Double Helix Medals dinner for supporters who donate $25,000 a year or more to help support CSHL Fellows, exceptionally talented young sci- 2 F our new trustees elected entists who show the capacity for high-level, independent research. CalTech President Emeritus and Nobel laureate 14 Women’s Partnership honors Elizabeth Watson David Baltimore discussed new approaches for dealing with the AIDS pandemic.
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