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Basic for the New Recruit

Authors

• Erin Conahan MSN, RN, ACNS-BC, CNRN, SCRN • Julie Fussner BSN, RN, CPHQ, SCRN

• The authors have nothing to disclose.

1 Objectives

• List causes of small vessel stroke vs large vessel stroke and differences in treatment • Describe inclusion/exclusion criteria for tPA and endovascular treatment • List elements of acute stroke work-up to identify risk factors

Stroke Facts

• Each year 795,000 occur in the United States • Stroke is the 5th leading cause of death in the United States • Stroke is the leading cause of adult disability • Up to 80% of strokes are preventable • During a stroke ~32,000 cells are lost per second… ~2 million brain cells lost per minute. • The brain ages 3.6 years for each hour untreated…

•Time is Brain

2 What is stroke?

Stroke occurs when a blood vessel to the brain is blocked or ruptured causing brain cells in the blood vessel territory to die .

What does it look like?

• Ischemic Stroke • Hemorrhagic Stroke

3 Cerebral Circulation

• Circle of Willis • Located at the base of the skull • Provides collateral circulation • Anterior Circulation • Carotid arteries • Anterior cerebral • Middle cerebral • Anterior communicating • Posterior Circulation • Vertebral • Basilar • Posterior cerebral • Posterior communicating

http://www.merckmanuals.com/professional/neurologic_disorders/stroke_cva/overview_of_stroke.html

5 Stroke Syndromes

1. Left Hemisphere 2. Right Hemisphere 3. Cerebellar 4. Brainstem 5. Hemorrhage

4 Left Hemisphere

Signs: • Aphasia • Right side weakness • Right side sensory loss • Right visual field cut • Left gaze

Right Hemisphere

Signs: • Neglect • Left side weakness • Left side sensory loss • Left visual field cut • Right gaze

5 Cerebellar

Signs: • Ataxia • Gait disturbance • Vertigo • Nystagmus • Ipsilateral Findings

Brainstem

Retrieved on 9/25/15 from: http://biology.clc.uc.edu/fankhauser/Labs/Anatomy_&_Physiology/A&P202/202_lecture_notes/05_Mesencephalon_Diencephalon.Jan12. pdf

6 Brainstem

The 5 D’s

Dizziness

Diplopia

Dysarthria

Dysphagia

Dystaxia

Retrieved 9/25/15 from: http://www.americannursetoday.com/assets/0/434/436/440/5120/5122/5154/5156/904adb93-6d32- 4770-83d7-e6f1ad1667d2.pdf

Intracranial Hemorrhages

4 Types Epidural (trauma) Subdural (trauma) Subarachnoid (traumatic or stroke) Intracerebral hemorrhages (stroke) Note difference between intraCRANIAL and intraCEREBRAL – both abbreviated “ICH”

7 Hemorrhage

Meninges (Outer to Inner) • – thick, fibrous covering of brain (and ) • – thin web-like membrane between dura and pia, below which flows the CSF in the subarachnoid space • Pia Mater – delicate covering of the brain and directly adherent to tissue

Retrieved from: http://www.mdguidelines.com/subarachnoid-hemorrhage-non-traumatic . Source: Medical Disability Advisor

SAH

Etiology – Traumatic (fall, blow to head) – Aneurysmal (ruptured aneurysm) – AVM (burst of AV malformation) Signs and symptoms – occur suddenly – “Worst headache of my life” (thunderclap HA) – Decrease/loss of consciousness/confusion – N/V – Photophobia – Hemiparesis/hemiplegia – Meningeal irritation

8 Intracerebral Hemorrhage

• Clinical Presentation • SBP often >220 mmHg • HA • N/V • Ataxia • Dizziness/Vertigo • Dysarthria • Nuchal Rigidity • Alterations in LOC

Stroke Assessments

• Support airway/breathing/circulation • Vital signs • POC Glucose • CT • NIHSS • Labs, EKG, CXR • CTA or MRA assess vessels • LP for SAH

9 NIH Stroke Scale

• Systematic assessment tool that provides a quantitative measure of stroke used world wide • 42 point scale • Higher the number the worse the stroke • NIHSS 2 or greater tPA given • “Too good” to treat research • www.nihss.org

NIH Stroke Scale

• Level of Consciousness Questions & Commands • Visual Fields • Facial Palsy • Motor arm & leg • Limb ataxia • Sensory • Best Language • Dysarthria • Neglect

10 What type of stroke did your patient have?

• Large vessel occlusion

• Lacunar Infarct

• Transient Ischemic Attack

• Stroke mimics

AIS: Large Artery Atherosclerosis Thrombosis

• Plaque narrows the vessel lumen resulting in turbulent blood flow. • The atherosclerotic plaque becomes unstable and ruptures, clotting factors are attracted and a thrombus forms. • Carotids / Aorta • Afib

11 AIS: Small Vessel Atherosclerosis

• Small-vessel ischemia occurs when plaque occludes small perforating vessels. • Typically results in lacunar strokes which accounts for ~ 25% of ischemic strokes. • Chronic medical conditions such as DM, HTN, HLD and smoking increases risk of small vessel disease.

TIA

• “Mini stroke” - Avoid term • Brief episode of neurological dysfunction lasting < 1 hour • Symptoms usually last 10-20 mins • Old Definition: less than 24 hours • New Definition: Evidence on MRI imaging • Important determinant of stroke risk • 3-10% pts stroke within 2 days • 9-17% pts stroke within 90 days • Within 1 year of TIA =12% will die

12 Stroke Mimics

• Hypoglycemia • Seizures • • Tumor • Abscess • Subdural

Imaging: CT vs MRI

• Why do they order the scan? • CT better for seeing acute blood or skull fractures • MRI better for ischemic stroke and tumor • CTA/MRA looking for blood vessel abnormalities (“A” means angio)

13 Treatment options: Time is brain • Blood pressure control for all types!! • IV tPA • Endovascular • Pharmacologic • Mechanical • Neurosurgery • Aneurysmal SAH Clipping and Coiling • External Ventricular Device • Decompressive Hemi craniotomy • Research • Neuroscience ICU / Stroke unit

**Find the cause to prevent future events!

tPA Inclusion/Exclusion Criteria

• Contraindications • ICH, SAH, active internal bleeding • Recent intracranial or intraspinal surgery or head trauma • Presence of intracranial conditions that may increase risk of bleeding • Bleeding diathesis • Uncontrolled hypertension • INR > 1.7 or use of NOAC • 3-4.5 hour window • >80 years old • Any anticoagulant use • History of CVA and diabetes

14 Modifiable Risk Factors

• Cardiovascular disease (CVD) • Cigarette smoking • Hypertension (HTN) • Drug use ( cocaine) • Asymptomatic carotid stenosis • Alcohol • A Fib • Obesity • Diabetes mellitus (DM) • Physical inactivity • Dyslipidemia • Sickle cell disease • Postmenopausal hormone therapy • Hypercoagulable states

Stroke Work-Up

• Cardiac monitoring • Angiography (CTA, MRA, angio) • Carotid duplex • Echocardiogram/TEE • FLP, HgA1C, Hypercoag panels

• Patient History!!

15 Importance of Nursing Assessment

• Ongoing neuro exam: 30% of stroke patients deteriorate in 1 st 24 hours • Bleeding, edema, stroke in evolution; seizures; side effects of treatment • VS trending • BP goals, temperature management, cardiac monitoring, oxygenation, blood glucose monitoring

Nursing Role of Preventing Complications • VTE, Pneumonia • Nutritional deficiency • Aspiration • Bowel or bladder dysfunction, UTI • Contractures/joint abnormalities • Skin breakdown • Depression • Falls

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