Tumor tissue Tumor stage Histological classification Array LocalizationANT2 signal value Breast I; Unknown Infiltrating duct carcinoma E5 237 I; Unknown Infiltrating duct carcinoma E6 378 III A; T1N2M0 Infiltrating duct carcinoma F5 390 III A; T1N2M0 Infiltrating duct carcinoma F6 322 I; T1N0M0 Mucinous adenocarcinoma G5 595 I; T1N0M0 Mucinous adenocarcinoma G6 388 III A; T3N1M0 Infiltrating duct carcinoma H5 568 III A; T3N1M0 Infiltrating duct carcinoma H6 532 II; T2N0M0 Paget's disease and infiltrating duct carcinoma of breast I5 457 II; T2N0M0 Paget's disease and infiltrating duct carcinoma of breast I6 477 III B; T4N1M0 Lobular carcinoma NOS J5 349 III B; T4N1M0 Lobular carcinoma NOS J6 513 II B; T2N1M0 Infiltrating duct carcinoma K5 603 II B; T2N1M0 Infiltrating duct carcinoma K6 458 II B; T2N1M0 Infiltrating duct carcinoma L5 547 II B; T2N1M0 Infiltrating duct carcinoma L6 598 I; T1N0M0 Infiltrating duct carcinoma M5 345 I; T1N0M0 Infiltrating duct carcinoma M6 616 II B; T2N1M0 Infiltrating duct carcinoma N5 398 II B; T2N1M0 Infiltrating duct carcinoma N6 532 Ovary I A; T1a2N0M0 Papillary serous cystadenoma, borderline malignancy E9 517 I A; T1a2N0M0 Papillary serous cystadenoma, borderline malignancy E10 520 Unknown; Unknown Leiomyoma NOS F9 596 Unknown; Unknown Leiomyoma NOS F10 754 III; T3NxM0 Adenocarcinoma NOS G9 445 III; T3NxM0 Adenocarcinoma NOS G10 1071 III C; T3cN1M0 Clear cell adenocarcinoma NOS H9 617 III C; T3cN1M0 Clear cell adenocarcinoma NOS H10 1061 Unknown; T2NxM0 Adenocarcinoma NOS I9 319 Unknown; T2NxM0 Adenocarcinoma NOS I10 639 II C; T2cN0M0 Leiomyoma NOS J9 438 II C; T2cN0M0 Leiomyoma NOS J10 1219 I A; Unknown Mucinous cystadenocarcinoma NOS K9 241 I A; Unknown Mucinous cystadenocarcinoma NOS K10 558 IV B; Unknown Adenocarcinoma NOS L9 227 IV B; Unknown Adenocarcinoma NOS L10 584 III C; T3N0M0 Serous surface papillary carcinoma M9 234 III C; T3N0M0 Serous surface papillary carcinoma M10 406 III A; T3NxM0 Papillary serous cystadenoma, borderline malignancy N9 415 III A; T3NxM0 Papillary serous cystadenoma, borderline malignancy N10 372 Lung II; T2N1M0 Bronchiolo-alveolar adenocarcinoma E21 335 II; T2N1M0 Bronchiolo-alveolar adenocarcinoma E22 360 Unknown; T3N2M0 Not Available F21 340 Unknown; T3N2M0 Not Available F22 237 Unknown; T3N1M0 Not Available G21 361 Unknown; T3N1M0 Not Available G22 307 Unknown; T3N0M0 Not Available H21 687 Unknown; T3N0M0 Not Available H22 392 I B; T2N0M0 Squamous cell carcinoma, keratinising type NOS I21 354 I B; T2N0M0 Squamous cell carcinoma, keratinising type NOS I22 337 I; T2N0M0 Squamous cell carcinoma, keratinising type NOS J21 443 I; T2N0M0 Squamous cell carcinoma, keratinising type NOS J22 474 III A; T3N1M0 Squamous cell carcinoma NOS K21 472 III A; T3N1M0 Squamous cell carcinoma NOS K22 611 II B; T2N1M0 Squamous cell carcinoma, keratinising type NOS L21 279 II B; T2N1M0 Squamous cell carcinoma, keratinising type NOS L22 577 Unknown; Unknown Adenocarcinoma NOS M21 558 Unknown; Unknown Adenocarcinoma NOS M22 747 I B; T2N0M0 Squamous cell carcinoma NOS N21 541 I B; T2N0M0 Squamous cell carcinoma NOS N22 904 Bladder II; T2N0M0 Transitional cell carcinoma NOS E29 915 II; T2N0M0 Transitional cell carcinoma NOS E30 369 III; T3N0M0 Transitional cell carcinoma NOS F29 513 III; T3N0M0 Transitional cell carcinoma NOS F30 1327 IV; T4bN0M0 Transitional cell carcinoma NOS G29 448 IV; T4bN0M0 Transitional cell carcinoma NOS G30 1190 II; T2N0M0 Transitional cell carcinoma NOS H29 547 II; T2N0M0 Transitional cell carcinoma NOS H30 846 III; T3aN0M0 Transitional cell carcinoma NOS I29 411 III; T3aN0M0 Transitional cell carcinoma NOS I30 539 Uterus I; T1N0M0 Adenocarcinoma NOS S5 286 I; T1N0M0 Adenocarcinoma NOS S6 356 I; T1b1N0M0 Adenocarcinoma NOS T5 350 I; T1b1N0M0 Adenocarcinoma NOS T6 472 Unknown; Unknown Not Available U5 429 Unknown; Unknown Not Available U6 589 Unknown; Unknown Squamous cell carcinoma, keratinising type NOS V5 725 Unknown; Unknown Squamous cell carcinoma, keratinising type NOS V6 554 Unknown; Unknown Not Available W5 616 Unknown; Unknown Not Available W6 403 II B; T2N0M0 Squamous cell carcinoma, keratinising type NOS X5 609 II B; T2N0M0 Squamous cell carcinoma, keratinising type NOS X6 1025 I A; T1aN0M0 Adenocarcinoma NOS Y5 564 I A; T1aN0M0 Adenocarcinoma NOS Y6 759 I B; T1b1N0M0 Squamous cell carcinoma NOS Z5 607 I B; T1b1N0M0 Squamous cell carcinoma NOS Z6 720 II B; T3N0M0 Adenocarcinoma NOS AA5 323 II B; T3N0M0 Adenocarcinoma NOS AA6 674 I; T1cN0M0 Adenocarcinoma NOS BB5 531 I; T1cN0M0 Adenocarcinoma NOS BB6 446 Cervix III B; T1b1N1M0 Squamous cell carcinoma, keratinising type NOS S9 449 III B; T1b1N1M0 Squamous cell carcinoma, keratinising type NOS S10 829 II A; T2N0M0 Adenocarcinoma NOS T9 413 II A; T2N0M0 Adenocarcinoma NOS T10 678 III B; T1b2N1M0 Squamous cell carcinoma, keratinising type NOS U9 316 III B; T1b2N1M0 Squamous cell carcinoma, keratinising type NOS U10 494 II A; T2aN0M0 Squamous cell carcinoma, keratinising type NOS V9 437 II A; T2aN0M0 Squamous cell carcinoma, keratinising type NOS V10 581 II; T2aN0M0 Adenocarcinoma NOS W9 346 II; T2aN0M0 Adenocarcinoma NOS W10 832 I-B2; T1b2N0M0 Adenocarcinoma NOS X9 418 I-B2; T1b2N0M0 Adenocarcinoma NOS X10 1591 I-A1; T1a1N0M0 Squamous cell carcinoma NOS Y9 499 I-A1; T1a1N0M0 Squamous cell carcinoma NOS Y10 614 I-B1; T1b1N0M0 Adenocarcinoma NOS Z9 510 I-B1; T1b1N0M0 Adenocarcinoma NOS Z10 528 I-B2; T1b2N0M0 Squamous cell carcinoma NOS AA9 523 I-B2; T1b2N0M0 Squamous cell carcinoma NOS AA10 788 I B; T1b1N0M0 Squamous cell carcinoma NOS BB9 570 I B; T1b1N0M0 Squamous cell carcinoma NOS BB10 1577 Thyroid gland I; T3N1M0 Papillary adenocarcinoma NOS S17 443 I; T3N1M0 Papillary adenocarcinoma NOS S18 264 IV; T4N1M0 Medullary carcinoma NOS T17 509 IV; T4N1M0 Medullary carcinoma NOS T18 635 Unknown; T3N0M0 Papillary adenocarcinoma NOS U17 374 Unknown; T3N0M0 Papillary adenocarcinoma NOS U18 467 II; T3N0M0 Papillary adenocarcinoma NOS V17 277 II; T3N0M0 Papillary adenocarcinoma NOS V18 410 III; T4N1aM0 Papillary adenocarcinoma NOS W17 526 III; T4N1aM0 Papillary adenocarcinoma NOS W18 562 II; T3N0M0 Papillary adenocarcinoma NOS X17 702 II; T3N0M0 Papillary adenocarcinoma NOS X18 576 II; T2N0M0 Papillary adenocarcinoma NOS Y17 414 II; T2N0M0 Papillary adenocarcinoma NOS Y18 505 I; T4N1bM0 Papillary adenocarcinoma NOS Z17 450 I; T4N1bM0 Papillary adenocarcinoma NOS Z18 405 II; T2N0M0 Papillary adenocarcinoma NOS AA17 497 II; T2N0M0 Papillary adenocarcinoma NOS AA18 425 II; T2N0M0 Follicular adenocarcinoma NOS BB17 427 II; T2N0M0 Follicular adenocarcinoma NOS BB18 728 Testis I; T2N0M0 Seminoma NOS S21 600 I; T2N0M0 Seminoma NOS S22 602 II; T2N0M0 Seminoma NOS T21 598 II; T2N0M0 Seminoma NOS T22 591 I; T1N0M0 Embryonal carcinoma NOS U21 544 I; T1N0M0 Embryonal carcinoma NOS U22 771 I; T1N0M0 Seminoma NOS V21 1272 I; T1N0M0 Seminoma NOS V22 486 I; T1N0M0 Seminoma NOS W21 973 I; T1N0M0 Seminoma NOS W22 1033 I; T1N0M0 Seminoma NOS X21 495 I; T1N0M0 Seminoma NOS X22 934 IV; T2NxM1 Endodermal sinus tumour Y21 519 IV; T2NxM1 Endodermal sinus tumour Y22 526 I; T1N0M0 Seminoma NOS Z21 529 I; T1N0M0 Seminoma NOS Z22 615 IV; T1N3M1 Seminoma NOS, metastatic AA21 520 IV; T1N3M1 Seminoma NOS, metastatic AA22 1371 III; T3N2M0 Seminoma NOS BB21 617 III; T3N2M0 Seminoma NOS BB22 1379 Human cancer cell linesHeLa Cervix adenocarcinoma S37 887 Daudi Burkitt's lymphoma T37 1089 K562 Chronic myelogenous leukemia U37 519 HL60 Acute promyelocytic leukemia V37 862 G361 Melanoma W37 585 A549 Lung carcinoma X37 421 MOLT4 Acute lymphoblastic leukemia Y37 850 SW480 Colorectal adenocarcinoma (Dukes' type B) Z37 779 Raji Burkitt's lymphoma AA37 700

Supplemental Table 1: Raw data for ANT2 overexpression in patients tissues. Tumor stage, histological classification array localization, according to BD Biosciences Clontech cancer array, are given. By phospho-imaging quantification, ANT2 level was normalized on ubiquitin signal and relative results are presented in this table.