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BOIRON(*) Parent Company REFERENCE DOCUMENT 2017 TABLE OF CONTENTS A few words from Christian Boiron ................................................................................... 4 1 Presentation of BOIRON group and its businesses .......................................................... 6 1.1 Indicators and key figures ................................................................................................................................................................................................................. 7 1.2 Presentation of BOIRON group and its development ............................................................................................................................. 10 1.3 Other information about BOIRON group ................................................................................................................................................................... 18 1.4 Analysis and comments on activities over the period ........................................................................................................................... 21 1.5 Risk factors and internal control ........................................................................................................................................................................................... 33 2 Corporate governance ....................................................................................................... 42 2.1 Corporate governance guidelines and rules ....................................................................................................................................................... 43 2.2 Composition, organization and functioning of the Board of Directors ......................................................................... 44 2.3 Authorization to increase or decrease the capital ...................................................................................................................................... 52 2.4 Factors likely to have an influence in the event of a public tender offer ................................................................... 53 2.5 Compensation of corporate officers ............................................................................................................................................................................... 56 3 Employee, environmental and social information ............................................................ 69 3.1 Employee information ......................................................................................................................................................................................................................... 70 3.2 Health Safety Environment .......................................................................................................................................................................................................... 80 3.3 Societal information .............................................................................................................................................................................................................................. 92 3.4 Independent third-party report on consolidated social, environmental and corporate information ........................................................................................................................................................................................................... 94 2 4 Annual financial statements ............................................................................................ 97 4.1 Consolidated financial statements ................................................................................................................................................................................... 98 4.2 Statutory auditors’ report on the consolidated financial statements ......................................................................... 158 4.3 Table showing the subsidiaries and holdings ................................................................................................................................................ 162 4.4 BOIRON parent company results for the last five years .................................................................................................................. 164 5 Legal information about the company and its capital .................................................. 167 5.1 Share capital .................................................................................................................................................................................................................................................. 168 5.2 Main shareholders .................................................................................................................................................................................................................................. 172 5.3 Employee shareholding .................................................................................................................................................................................................................. 175 5.4 Incorporation and articles of association ............................................................................................................................................................. 176 5.5 Report of the Board of Directors to the Combined Shareholders’ Meeting of May 17, 2018 - extraordinary part ................................................................................................................................................................................................................................... 181 5.6 Draft resolutions put to the Combined Shareholder’s Meeting of May 17, 2018 ............................................. 183 6 Other information ............................................................................................................ 189 6.1 Person responsible for the Reference document ..................................................................................................................................... 190 6.2 Statutory auditors .................................................................................................................................................................................................................................... 191 6.3 Public information .................................................................................................................................................................................................................................. 193 6.4 Provisional publication schedule ...................................................................................................................................................................................... 193 6.5 List of BOIRON parent company establishments as at December 31, 2017 .......................................................... 194 6.6 Concordance table of the Reference document ......................................................................................................................................... 196 6.7 Concordance table of financial annual report and management report .............................................................. 200 6.8 Concordance table of employee, environmental and societal information ....................................................... 202 6.9 Glossary ................................................................................................................................................................................................................................................................. 204 This is a free translation into English of the BOIRON 2017 Reference document issued of the French language and is provided solely for the convenience of English speaking readers. In case of discrepancy, the French version prevails. 3 A few words from Christian Boiron A few words from Christian Boiron Ever since the company’s origin, our objective remains the worldwide development of Homeopathy. The short and medium-term development of our company, and the specific development of Homeopathy, enable us to consider a variety of approaches: 1 - Growth balanced between medical prescriptions, pharmaceutical advice and self-medication; 2 - This should lead to an increase in both generic medicines and specialty products, as has been the case in the past; 3 - It is highly probable that, as in the field of allopathic medicine, compounded product prescription may be gradually restricted. This will necessarily lead to change within our organization, especially and mainly in France; 4 - Regarding production, we will have to face several developments: • the gradual reduction in compounded products; • an increase in the number of international subsidiaries; • an increased portion of the industrial activities consolidated at the new site in Messimy which will require an increase in production investments; 4 - • the creation of a logistics platform in the commune of Les Olmes (Rhône department). 5 - With regard to business development, every subsidiary is faced with growth opportunities and regulatory issues, as well as differing and changing competitive realities. The multinational development of our company will inevitably lead to contrasting short-term and medium-term changes in the development of subsidiaries. 6 - Finally,
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