Antibody Cures West Nile Virus in Mice by MICHAEL C

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Antibody Cures West Nile Virus in Mice by MICHAEL C Washington University School of Medicine Digital Commons@Becker Washington University Record Washington University Publications 4-29-2005 Washington University Record, April 29, 2005 Follow this and additional works at: http://digitalcommons.wustl.edu/record Recommended Citation "Washington University Record, April 29, 2005" (2005). Washington University Record. Book 1037. http://digitalcommons.wustl.edu/record/1037 This Article is brought to you for free and open access by the Washington University Publications at Digital Commons@Becker. It has been accepted for inclusion in Washington University Record by an authorized administrator of Digital Commons@Becker. For more information, please contact [email protected]. Medical News: Ted Cicero to step Forum: "A Conversation With Huston Washington People: Steven S. Smith down as vice chancellor for research Smith" May 3 in Women's Building opened the Senate doors, walked on in 8 April 29, 2005 Volume 29 No. 31 Wellington University in St. Louis Antibody cures West Nile virus in mice BY MICHAEL C. PURDY survival rate after West Nile infec- "They also suggest antibody-based explore new Diamond said. "It also completely tion, scientists found that single therapeutics may have a broader possibilities for protected against death from the A newly developed monoclon- doses of the antibodies given soon utility against other infectious treating related disease." al antibody can cure mice after infection could boost sur- diseases." viruses that are Researchers will report their infected with the West Nile vival rates to 90 percent or higher. He pointed out that Macroge- more prolific results in the May issue of Nature virus, according to University sci- "To our knowledge, these ex- nics Inc. of Rockville, Md., a com- causes of hu- Medicine. entists. periments are the first successful pany that contributed to the study man disease In 2004, West Nile virus repor- If further studies confirm the demonstration of the use of a and licensed the antibody from and death. tedly caused 2,470 infections and effectiveness and safety of the humanized antibody as a post- the University, must complete "We could 88 deaths in the United States. antibody, it could become one of exposure therapy against a viral other preliminary studies before Diamond give a single Most infections with the virus are the first monoclonal antibodies disease," said senior investigator the antibody can be tested in hu- dose of this mild or symptom-free, but infec- used as a treatment for an infec- Michael S. Diamond, M.D., Ph.D., mans. But Diamond and his col- antibody to mice as long as five tions in people with weakened tious disease. assistant professor of molecular leagues are excited both by the days after infection, when West immune systems and those over In a strain of mice that nor- microbiology, of pathology and apparent potency of the antibody Nile virus had entered the brain, 50 sometimes lead to serious corn- mally has only about a 10 percent immunology and of medicine. and its potential to help them and it could still cure them," See Antibody, Page 6 Syverud is named School of Law dean BY JESSICA MARTIN that he was stepping down as Vanderbilt's law dean effective Kent D. Syverud, J.D., dean of June 30, 2005. the Vanderbilt University Law "I think we succeeded in hir- School, has been named dean of ing the most talented law school the WUSTL School of Law effec- dean candidate in the country," tive Jan. 1, according to Chancel- Keating said. "Kent Syverud has a lor Mark S. Wrighton. national reputation for excellence Syverud will also become the and integrity in everything that Ethan A.H. Shepley University he does. Professor. "While he was dean at Van- Joel Seligman, J.D, who came derbilt Law School, Kent was par- to WUSTL in 1999 to serve as law ticularly effective in reaching out dean, will become president of to alumni, in recruiting and re- the University of Rochester July 1. taining the best faculty, and in Prior to Syverud's arrival, strengthening Vanderbilt's career Daniel L. Keating, J.D, WUSTL's services opera- associate dean for academic af- tion. Joel fairs and the Tyrrell Williams Pro- Seligman is a fessor of Law, will serve as dean. very tough act "I am delighted that Kent to follow, but I Syverud has agreed to serve as am confident dean of the School of Law," Wrigh- that Kent will ton said. "Kent has been an im- oversee another pressive force at Vanderbilt. His great era at the outstanding leadership and schol- School of Law." arship will be an integral part of Syverud Keating Washington University School of chaired the Law's continued development as search committee that recom- one of the nation's premier law mended Syverud. It S 3 beautiful day University community members (from left) Yang Gao, Huiyun Shan and schools. Among his accomplishments Zihan Huang perform Qing FengXIan Qing, or Wild Wind and Happiness, a Han folk dance that "Kent is a very experienced at Vanderbilt are the complete portrays a picture of a Chinese town on a sunny spring day. The performance was part of the academic leader, and I welcome design, construction and fund- George Warren Brown School of Social Work's 11th annual International Festival April 22 in his taking on special projects and raising for a $24 million law Brown Hall. The theme of this year's event was "Crossroads: Celebrating One World." interdisciplinary initiatives for the school facility; and the creation of University, in addition to his re- a law and business program, an sponsibilities as law dean. I espe- L.L.M. program for foreign law- cially look forward to working yers, and clinical programs on do- Student Worker Alliance sit-in comes to an end with him as a member of the mestic violence and community BY ANDY CLENDENNEN nies that provide basic services to the University on a University Council." economic development. 1 contractual basis to assure conformity with the com- Syverud is looking forward to He also recruited 30 new fac- After nearly three weeks of protesting, approximate- mitments made in the "Principles and Guidelines for his new post. ulty members and launched a $40 ly 14 members of the Student Worker Alliance Basic Service Contracts," which became University "Washington University has million capital campaign that will (SWA) agreed to call off their sit-in in South Brook- policy last fall. In addition, the University is opening a great law school within a great conclude in June 2008. ings Hall and Brookings Quadrangle when presented expanded discussions to determine if improvements university, and I am honored to with a letter from Chancellor Mark S. Wrighton can be made, especially on worker health-care issues. be coming to St. Louis to join its About Kent Syverud April 22. • The University will join the Workers Rights faculty," Syverud said. "I love Van- Syverud has established an extra- In the letter, Wrighton again outlined what the Consortium, in addition to its present membership derbilt and have benefited so ordinary reputation as a scholar University has committed to do and set forth some in the Fair Labor Association, to maintain its policy much from my colleagues here. in legal education, complex litiga- additional steps to be addressed at the end of the sit-in. of supporting international and national efforts pro- I hope to be a worthy steward at tion, insurance and civil proce- The University agreed to do the following: moting respect for labor rights around the world. Washington University as well." dure. He is the author of numer- • Beginning in the 2005-06 fiscal year, the Univer- • The University respects the rights and decisions Syverud announced in 2003 See Syverud, Page 6 sity will commit $500,000 toward improving the of employees to choose to be represented by a union wages and benefits of lower-paid service workers. and to collectively bargain with their employer. The Also, beginning in the 2006-07 fiscal year, the Univer- University is committed to remaining neutral in the sity will commit an additional $500,000 annually labor-relations decisions of its independent service "I think we succeeded in hiring the most talented toward the same purpose, bringing the annual total contractors and their employees. law school dean candidate in the country.... to $1 million. • The University will strive to do business with • The University will appoint a team to review service contractors who recognize, support and re- Joel Seligman is a very tough act to follow, University priorities with the intent of identifying spect fair labor practices. In selecting service contrac- but I am confident that Kent will oversee what additional resources might be available to tors, adherence to fair labor practices will be a criteri- address the ongoing needs of lower-paid service on for selection, in addition to those criteria already another great era at the School of Law." workers. included in the "Principles and Guidelines for Basic DANIEL L KEATING • The University will soon meet with the compa- See Sit-in, Page 6 2 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS Service award changes name to honor Virgils BY BARBARA REA He led the Olin School of Robert L. Virgil pres- Business through its biggest ents a 2005 Gerry and Seven recipients of the 2005 period of growth and develop- Bob Virgil Ethic of Gerry and Bob Virgil Ethic ment when he served as dean Service Award to of Service Award were hon- from 1977-1993. In 1992, he was Elinor Nelson, who ored at an April 21 ceremony for named executive vice chancellor works in the their dedication to improving the for university relations.
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