Oral Med Pathol 8 (2003) 139 Lipomatous Pleomorphic Adenoma in the Palatine Gland Kenichi Matsuzaka1, Hideki Fukumoto2, Chiaki Watanabe2, Masaki Shimono3 and Takashi Inoue1 1Oral Health Science Center and Dept. of Clinical Pathophysiology, Tokyo Dental College, Chiba, Japan 2Dept. of Oral Maxillofacial Surgery, National Mito Hospital, Ibaraki, Japan 3Oral Health Science Center and Dept. of Pathology, Tokyo Dental College, Chiba, Japan Matsuzaka K, Fukumoto H, Watanabe C, Shimono M and Inoue T. Lipomatous pleomorphic adenoma in the palatine gland. Oral Med Pathol 2003; 8: 139-140, ISSN 1342-0984 Lipomatous pleomorphic adenoma is an unusual subtype of adenoma with a lipomatous stromal component. Although there are a few reports about lipomatous pleomorphic adenoma in the parotid gland, we report an extremely rare case of lipomatous pleomorphic adenoma in the palatine gland of a 33-year-old female. Histologically, approximately 80% of the tumor tissue was fatty tissue containing univacuolar adipocytes. The pleomorphic epithelial elements consisted of duct-like cells forming small lumina and also consisted of spindle-shaped myoepithelial cells. Key words: lipomatous pleomorphic adenoma, palatine gland, adipocyte Correspondence: Kenichi Matsuzaka, Oral Health Science Center and Dept. of Clinical Pathophysiology, Tokyo Dental College, 1-2-2, Masago, Mihama-ku, Chiba 261-8502, Japan. Phone: +81-43-270-3581, Fax: +81-43-270-3583, E-mail:
[email protected] Introduction Pathologically, the consistent histopathological feature Pleomorphic adenoma is the most common neo- was an encapsulated mass of epithelial and modified plasm of the salivary glands (1). Extensive lipomatous myoepithelial elements intermingled with duct-like struc- involvement of the stroma is a rare finding in pleomor- tures.