2003 NAMCS Public Use File Documentation

Total Page:16

File Type:pdf, Size:1020Kb

2003 NAMCS Public Use File Documentation 2003 NAMCS MICRO-DATA FILE DOCUMENTATION PAGE 1 ABSTRACT This material provides documentation for users of the micro-data file of the 2003 National Ambulatory Medical Care Survey (NAMCS). The NAMCS is a national probability sample survey of visits to office-based physicians conducted by the National Center for Health Statistics, Centers for Disease Control and Prevention. It is a component of the National Health Care Survey which measures health care utilization across a variety of health care providers. Section I, "Description of the National Ambulatory Medical Care Survey," includes information on the scope of the survey, the sample, field activities, data collection procedures, medical coding procedures, population estimates, and sampling errors. Section II provides technical information, including a detailed description of the contents of each data record by location, and a list of physician specialties represented in the survey. Section III contains marginal data and estimates for selected items on the data record. The appendixes contain sampling errors, instructions and definitions for completing the Patient Record form, and lists of codes used in the survey. PAGE 2 2003 NAMCS MICRO-DATA FILE DOCUMENTATION SUMMARY OF CHANGES FOR 2003 The 2003 NAMCS public use micro-data file contains many of the same items as the 2002 file. The items listed below were added or modified for 2003. 1. New/Modified Items a. Was patient’s temperature taken? [TEMPTAKE] – new for 2003. b. Temperature reading (Fahrenheit) [TEMPF] – new for 2003. c. Blood pressure reading (BPSYS, BPDIAS] – new for 2003. d. Diagnostic/screening services – Glucose test [GLUCOSE] is new for 2003. e. Diagnostic/screening services – Glycohemoglobin test [HGBA] is new for 2003. f. Diagnostic/Screening Services – Electrolytes test (ELECTROL] is new for 2003. g. Medications & Injections – increased drug entry fields from six to eight h. Patient ethnicity imputed? [ETHNICFL] - In 2003, missing data for patient ethnicity were imputed for the first time since 1996. A flag was added to identify the imputed records. i. “Have you or anyone in your practice seen this patient before?” imputed? [SENBEFL] – In 2003, missing data for this item were imputed for the first time since 1996. A flag was added to identify the imputed records. j. “If yes, how many past visits in the last 12 months?” imputed? [PASTFL] – In 2003, missing data for this item were imputed. A flag was added to identify the imputed records. Most of these items were added based on suggestions from the expert panel of consultants involved with the NAMCS redesign. Several of them (temperature reading, blood pressure reading, glucose and glycohemoglobin test) have been collected in the emergency department component of the National Hospital Ambulatory Medical Care Survey since 2001. In addition, several items from the Physician Induction Interview, reflecting aspects of the physician's practice, have been added to the NAMCS public use file for the first time in 2003. While data users cannot make physician-level estimates with publicly available data, these items would be especially useful in models as predictors of outcome variables. Also, some of the items could be used to examine differences in visit estimates (for example, looking at visits by disposition status grouped by physicians according to their stated difficulty in making specialty consultation referrals). These new items are: k. Percent of physician’s practice revenue from patient care that comes from Medicare, Medicaid, Private Insurance, and Other [PRMCARER, PRMAIDR, PRPRVTR, PROTHR] (presented as quartiles for each category) l. How many managed care contracts does this practice have? (includes health maintenance organizations, preferred provider organization, independent practice associations, and point-of-service plans) (presented in aggregate categories) [MANCAREC] m. Percent of patient care revenue received by this practice coming from {these) managed care contracts (presented as quartiles) [PRMANR] n. Does your practice use electronic medical records (excluding billing records)? [EMEDREC] o. Does your practice submit claims electronically (electronic billing)? [EBILLREC] p. Are you currently accepting new patients into your practice? [ACEPTNEW] q. From these new patients which of the following types of payment do you accept – Capitated private insurance, non-capitated private insurance, Medicare, Medicaid, Workers compensation, Self-pay, No charge? [CAPITATE, NOCAP, NMEDCARE, NMEDCAID, NWORKCMP, NSELFPAY, NNOCHRGE] r. In the past 12 months, has your practice experienced any difficulty in referring patients with the following types of health insurance for specialty consultation – Medicaid, Medicare, Private Insurance, Uninsured? [REFMDCAD, REFMDCAR, REFPRIV, REFUNINS] 2003 NAMCS MICRO-DATA FILE DOCUMENTATION PAGE 3 Sample Design Variables As first stated in the 2002 NHAMCS public use file documentation, the multi-stage masked sample design variables used for variance estimation in SUDAAN are no longer included on the file. The variables, CSTRATM and CPSUM, which were first included in the 2002 release, take their place, and can be used to estimate variance with SUDAAN’s with-replacement (WR) option, as well as with Stata, SPSS, SAS, and other statistical software packages utilizing an ultimate cluster design for variance estimation. These variables and their use are described more fully in the “Relative Standard Errors” section of the public use file documentation. Drug Characteristics The Ambulatory Care Drug Database underwent substantial revisions in 2002, as described in the 2002 NAMCS Public Use Data File Documentation. For 2003, we continued to add new drugs and update the database as necessary. Because of these revisions to the file, and also because of the addition of a second and third therapeutic class for each drug beginning in 2002, trend analysis with survey data prior to 2002 becomes more problematic. We recommend that researchers download the Drug Characteristics file, which is updated annually, from the Ambulatory Health Care Data website. The characteristics from this file can be applied by matching on drug codes to previous years of data in order to get the most accurate results when doing analysis of drug trends, especially using therapeutic class. We recommend that you use the SAS program (which can be adapted for use with other software) that we have developed and which is downloadable at our website. This program will apply the new characteristics from the most current version of the drug database to previous years of data. Our web address is: http://www.cdc.gov/nchs/about/major/ahcd/ahcd1.htm Reason for Visit Classification The Reason for Visit Classification, developed by NCHS to code the patient’s expressed reason for the medical visit, is updated periodically to reflect reasons for which codes were not previously available and to modify some existing codes to improve the classification scheme. The version of the classification used in a particular survey year is included in that year’s public use documentation. Because of the changes that occur over time, researchers are advised, when doing multi-year analysis involving reason for visit, to check each year’s classification to make sure they are using the best and most complete set of codes for their analysis. Weighting and Estimation Sample data are weighted to produce annual national estimates. Beginning in the 2003 data year, estimates were calculated using a weight that includes a revised adjustment for non- response. In previous years the adjustment accounted for non-response by physician specialty, geographic region, and metropolitan statistical area status. The revised non- response adjustment also accounts for non-response from physicians by practice size, as measured by number of weekly visits, and for variability in number of weeks that participating physicians saw patients during the year. Previously, these characteristics were assumed to be the same for physicians providing patient encounter information and those not providing such information. Research conducted with 2003 data, however, showed that physicians with larger visit volumes were more likely to refuse to participate. In addition, physicians who did not see patients during their assigned week saw patients fewer weeks annually than physicians who did see patients. The revised non-response adjustment uses information collected from physicians during the induction interview. Information on usual weekly visit volume has been collected since 2001 from sample physicians who refuse to provide encounter information. Researchers conducting trend analysis should be aware that estimates based on the revised estimator are expected to be higher in magnitude than estimates using the previous estimator PAGE 4 2003 NAMCS MICRO-DATA FILE DOCUMENTATION when there is greater non-response from physicians with greater volume. NCHS does not plan to release revised estimates for 2001 and 2002 based on the revised estimator. However, more information on the effects of the revised weight relative to the original weight on visit estimates for 2001-2003 will be published in the forthcoming 2003 NAMCS summary report. It is recommended that researchers presenting trend data include a footnote referencing the effects of the revised estimator on their estimates. The following is given as an example: “Beginning in 2003, the National Center for Health Statistics revised the estimator used to produce visit estimates for National
Recommended publications
  • Guidance on Identification of Alternatives to New Pops
    Stockholm Convention on Persistent Organic Pollutants Guidance on identification of alternatives to new POPs Secretariat of the Stockholm Convention Concept of “Substitution” under the Stockholm Convention • The substitution is a strategy promoted by the Stockholm Convention to reach its objectives • Parties that are still producing or using the new POPs listed in Annex A, will need to search and identify alternatives to replace them • In the case of PFOS and for the exemptions for uses allowed by the Convention, these group of chemicals will be eventually prohibited and Parties are therefore encouraged to find alternatives to substitute them 2 Availability of alternatives • Currently, some countries have phased out the use of some of the new POPs, and there are feasible alternatives available to replace them Alternatives Chemical Name Use Ethoprop, oxamyl Pesticide to control banana root borer Cyfluthrin, Imidacloprid Pesticide to control tobacco wireworms Azadirachtin, bifenthrin, boric acid, carbaryl, Pesticide to control capsaicin, cypermethrin, cyfluthrin, ants and/or deltamethrin, diazinon, dichlorvos, cockroaches esfenvalerate, imidacloprid, lamda-cyhalothrin, Chlordecone malathion, permethrin, piperonyl butoxide, pyrethrins, pyriproxyfen, resmethrin, s- bioallerthrin, tetramethrin Bacillus thuringiensis, cultural practices such Pest management as crop rotation, intercropping, and trap cropping; barrier methods, such as screens, and bagging of fruit; use of traps such as pheromone and light traps to attract and kill insects. 3
    [Show full text]
  • Lindane – Product Discontinuation • the FDA Announced the Discontinuation of Lindane 1% Lotion and 1% Shampoo Due to Product Line Rationalization
    Lindane – Product Discontinuation • The FDA announced the discontinuation of Lindane 1% lotion and 1% shampoo due to product line rationalization. — The discontinuation is not due to product quality, safety or efficacy concerns. • Lindane lotion is indicated for the treatment of scabies (infestations of Sarcoptes scabei) only in patients who cannot tolerate other approved therapies, or have failed treatment with other approved therapies. • Lindane shampoo is indicated for the treatment of head lice (infestations of Pediculus humanus capitis), crab lice (infestations of Pthirus pubis), and their ova only in patients who cannot tolerate other approved therapies, or have failed treatment with other approved therapies. • Other prescription products indicated to treat lice include Ulesfia® (benzyl alcohol) 5% lotion, Ovide® (malathion) 0.5% lotion, Natroba™ (spinosad) 0.9% topical suspension, and Sklice® (ivermectin) 0.5% lotion. — Over-the-counter products indicated to treat lice include various formulations of 1% permethrin (eg, Nix®), various formulations of piperonyl butoxide/pyrethrins (eg, CareOne® Lice), and other miscellaneous products such as Lycelle®. • Other prescription products indicated to treat scabies include Eurax® (crotamiton) 10% cream and 10% lotion and Elimite™ (permethrin) 5% cream. optumrx.com OptumRx® specializes in the delivery, clinical management and affordability of prescription medications and consumer health products. We are an Optum® company — a leading provider of integrated health services. Learn more at optum.com. All Optum® trademarks and logos are owned by Optum, Inc. All other brand or product names are trademarks or registered marks of their respective owners. This document contains information that is considered proprietary to OptumRx and should not be reproduced without the express written consent of OptumRx.
    [Show full text]
  • (12) Patent Application Publication (10) Pub. No.: US 2014/0100249 A1 Sears Et Al
    US 201401.00249A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2014/0100249 A1 Sears et al. (43) Pub. Date: Apr. 10, 2014 (54) THERAPEUTIC TREATMENT A63/37 (2006.01) A613 L/45 (2006.01) (71) Applicants: Douglas Sears, Oak Park, CA (US); A613 L/4458 (2006.01) Michael Reilly, Oak Park, CA (US) (52) U.S. Cl. CPC ............... A61K 45/06 (2013.01); A61 K3I/451 (72) Inventors: Douglas Sears, Oak Park, CA (US); (2013.01): A613 L/4458 (2013.01); A61 K Michael Reilly, Oak Park, CA (US) 3 1/137 (2013.01); A61 K31/165 (2013.01) USPC .......................................................... S14/325 (21) Appl. No.: 14/046,528 (57) ABSTRACT (22) Filed: Oct. 4, 2013 This invention discloses a treatment for a patient receiving O O medication to treat an attention deficit disorder Such as Related U.S. Application Data ADHD wherein the treatment results in a loss of appetite and (60) Provisional application No. 61/744,948, filed on Oct. impairment of the patient's attentiveness. The treatment com 9, 2012, now abandoned. bines a treatment for an attention deficit disorder with an appetite stimulant, wherein the appetite stimulant increases Publication Classification the caloric intake of a patient, which can increase the patients attentiveness. The combination treatment can be given for an (51) Int. Cl. indefinite, including, without limitation, life-long, to allow a A6 IK 45/06 (2006.01) patient to maintain normal caloric intake during treatment for A6 IK3I/65 (2006.01) an attention deficit disorder. 8aasaias: Patent Application Publication Apr. 10, 2014 Sheet 1 of 22 US 2014/010O249 A1 Figure i: improvement in Atiention with increased Caiotic intake 8aakast Patent Application Publication Apr.
    [Show full text]
  • Classification of Medicinal Drugs and Driving: Co-Ordination and Synthesis Report
    Project No. TREN-05-FP6TR-S07.61320-518404-DRUID DRUID Driving under the Influence of Drugs, Alcohol and Medicines Integrated Project 1.6. Sustainable Development, Global Change and Ecosystem 1.6.2: Sustainable Surface Transport 6th Framework Programme Deliverable 4.4.1 Classification of medicinal drugs and driving: Co-ordination and synthesis report. Due date of deliverable: 21.07.2011 Actual submission date: 21.07.2011 Revision date: 21.07.2011 Start date of project: 15.10.2006 Duration: 48 months Organisation name of lead contractor for this deliverable: UVA Revision 0.0 Project co-funded by the European Commission within the Sixth Framework Programme (2002-2006) Dissemination Level PU Public PP Restricted to other programme participants (including the Commission x Services) RE Restricted to a group specified by the consortium (including the Commission Services) CO Confidential, only for members of the consortium (including the Commission Services) DRUID 6th Framework Programme Deliverable D.4.4.1 Classification of medicinal drugs and driving: Co-ordination and synthesis report. Page 1 of 243 Classification of medicinal drugs and driving: Co-ordination and synthesis report. Authors Trinidad Gómez-Talegón, Inmaculada Fierro, M. Carmen Del Río, F. Javier Álvarez (UVa, University of Valladolid, Spain) Partners - Silvia Ravera, Susana Monteiro, Han de Gier (RUGPha, University of Groningen, the Netherlands) - Gertrude Van der Linden, Sara-Ann Legrand, Kristof Pil, Alain Verstraete (UGent, Ghent University, Belgium) - Michel Mallaret, Charles Mercier-Guyon, Isabelle Mercier-Guyon (UGren, University of Grenoble, Centre Regional de Pharmacovigilance, France) - Katerina Touliou (CERT-HIT, Centre for Research and Technology Hellas, Greece) - Michael Hei βing (BASt, Bundesanstalt für Straßenwesen, Germany).
    [Show full text]
  • Crotamiton, an Anti-Scabies Agent, Suppresses Histamine- and Chloroquine-Induced Itch Pathways in Sensory Neurons and Alleviates Scratching in Mice
    Original Article Biomol Ther 28(6), 569-575 (2020) Crotamiton, an Anti-Scabies Agent, Suppresses Histamine- and Chloroquine-Induced Itch Pathways in Sensory Neurons and Alleviates Scratching in Mice Da-Som Choi1,2,†, Yeounjung Ji1,2,†, Yongwoo Jang3, Wook-Joo Lee1,2 and Won-Sik Shim1,2,* 1College of Pharmacy, Gachon University, Incheon 21936, 2Gachon Institute of Pharmaceutical Sciences, Incheon 21936, 3Department of Biomedical Engineering, Hanyang University, Seoul 04736, Republic of Korea Abstract Crotamiton is an anti-scabies drug, but it was recently found that crotamiton also suppresses non-scabietic itching in mice. How- ever, the underlying mechanism is largely unclear. Therefore, aim of the study is to investigate mechanisms of the anti-pruritic effect of crotamiton for non-scabietic itching. Histamine and chloroquine are used as non-scabietic pruritogens. The effect of crota- miton was identified using fluorometric intracellular calcium assays in HEK293T cells and primary cultured dorsal root ganglion (DRG) neurons. Further in vivo effect was evaluated by scratching behavior tests. Crotamiton strongly inhibited histamine-induced calcium influx in HEK293T cells, expressing both histamine receptor 1 (H1R) and transient receptor potential vanilloid 1 (TRPV1), as a model of histamine-induced itching. Similarly, it also blocked chloroquine-induced calcium influx in HEK293T cells, express- ing both Mas-related G-protein-coupled receptor A3 (MRGPRA3) and transient receptor potential A1 (TRPA1), as a model of histamine-independent itching. Furthermore, crotamiton also suppressed both histamine- and chloroquine-induced calcium influx in primary cultures of mouse DRG. Additionally, crotamiton strongly suppressed histamine- and chloroquine-induced scratching in mice. Overall, it was found that crotamiton has an anti-pruritic effect against non-scabietic itching by histamine and chloroquine.
    [Show full text]
  • Specialty Direct Supply Drug List
    DRAFT SPECIALTY DIRECT SUPPLY DRUG LIST (DSDL) 9/27/2005 Drug Description Effective Date 5-HT3 Receptor Antagonists ALOXI - SOLN 12/09/2004 ANZEMET - SOLN 12/09/2004 ANZEMET - TABS 12/09/2004 KYTRIL - SOLN 12/09/2004 KYTRIL - TABS 12/09/2004 Additional Solids ALPROSTADIL - POWD 12/09/2004 PROSTAGLANDIN E1 - POWD 12/09/2004 Agents for Gaucher Disease CEREZYME - SOLR 12/09/2004 Agents for Pheochromocytoma PHENTOLAMINE MESYLATE - SOLR 12/09/2004 REGITINE - SOLR 12/09/2004 Alkylating Agents CARBOPLATIN - SOLN 12/09/2004 CARBOPLATIN - SOLR 12/09/2004 CISPLATIN - SOLN 12/09/2004 CISPLATIN AQ - SOLN 12/09/2004 ELOXATIN - SOLR 12/09/2004 MYLERAN - TABS 12/09/2004 PARAPLATIN - SOLN 12/09/2004 PARAPLATIN - SOLR 12/09/2004 PLATINOL - SOLN 12/09/2004 PLATINOL AQ - SOLN 12/09/2004 THIOPLEX - SOLR 12/09/2004 THIOTEPA - SOLR 12/09/2004 Alpha-Proteinase Inhibitor (Human) ARALAST - SUSR 07/01/2005 PROLASTIN - SUSR 07/01/2005 ZEMAIRA - SOLR 07/01/2005 AMINOGLYCOSIDES APOGEN - SOLN 12/09/2004 GARAMYCIN - SOLN 12/09/2004 GENTAMICIN SULFATE - SOLN 12/09/2004 G-MYCIN - SOLN 12/09/2004 JENAMICIN - SOLN 12/09/2004 NEBCIN - SOLN 12/09/2004 NEBCIN MDV - SOLN 12/09/2004 STORZ-G - SOLN 12/09/2004 TOBI - NEBU 12/09/2004 TOBRAMYCIN SULFATE - SOLN 12/09/2004 TOBRAMYCIN SULFATE FLIPTO - SOLN 12/09/2004 Antianxiety Agents - Misc. rev A Page 1 of 13 MaineCare Direct Supply Drug List (DSDL) Drug Description Effective Date Antianxiety Agents - Misc. - Continued - DROPERIDOL - POWD 12/09/2004 DROPERIDOL - SOLN 12/09/2004 INAPSINE - SOLN 12/09/2004 Antiarrhythmics Type III
    [Show full text]
  • TITLE: Lindane and Other Treatments for Lice and Scabies: a Review of Clinical Effectiveness and Safety
    TITLE: Lindane and Other Treatments for Lice and Scabies: A Review of Clinical Effectiveness and Safety DATE: 11 June 2010 CONTEXT AND POLICY ISSUES: Head lice infestation (Pediculosis capitis) affects millions of children and adults worldwide each year.1 Direct head-to-head contact is the most common mode of transmission.2 The highest prevalence of infestation occurs in school aged children aged three to eleven years, with girls being more commonly affected than boys.1,2 Although head lice are not generally associated with serious morbidity, they are responsible for significant social embarrassment and lost productivity in schools or offices.1 Scabies, an infestation of the skin by the mite Sarcoptes scabiei, represents a common public health concern particularly in overcrowded communities with a high prevalence of poverty.3 Scabies is transmitted by close-person contact and occasionally by clothing or linens.3 Complications include secondary bacterial infections and post-streptococcal glomerulonephritis.3 Topical products available in Canada for the treatment of head lice and scabies are presented in Appendix 1 and Appendix 2. Insecticidal agents such as permethrin and lindane have historically been considered the standard treatments for head lice and scabies.2,3 Toxicity is low following topical administration of permethrin due to minimal percutaneous absorption.4 However, several jurisdictions have banned lindane due to concerns of neurotoxicity and bone marrow suppression, as well as potential negative effects on the environment (contamination of waste water).5 Furthermore, widespread use of permethrin, pyrethrins/piperonyl butoxide, and lindane has led to resistance and higher rates of treatment failure.6 Resistance patterns and rates to these agents in Canada have not yet been studied.6 Due to concerns surrounding resistance and neurotoxicity, patients and caregivers have searched for alternative treatments.
    [Show full text]
  • )&F1y3x PHARMACEUTICAL APPENDIX to THE
    )&f1y3X PHARMACEUTICAL APPENDIX TO THE HARMONIZED TARIFF SCHEDULE )&f1y3X PHARMACEUTICAL APPENDIX TO THE TARIFF SCHEDULE 3 Table 1. This table enumerates products described by International Non-proprietary Names (INN) which shall be entered free of duty under general note 13 to the tariff schedule. The Chemical Abstracts Service (CAS) registry numbers also set forth in this table are included to assist in the identification of the products concerned. For purposes of the tariff schedule, any references to a product enumerated in this table includes such product by whatever name known. Product CAS No. Product CAS No. ABAMECTIN 65195-55-3 ACTODIGIN 36983-69-4 ABANOQUIL 90402-40-7 ADAFENOXATE 82168-26-1 ABCIXIMAB 143653-53-6 ADAMEXINE 54785-02-3 ABECARNIL 111841-85-1 ADAPALENE 106685-40-9 ABITESARTAN 137882-98-5 ADAPROLOL 101479-70-3 ABLUKAST 96566-25-5 ADATANSERIN 127266-56-2 ABUNIDAZOLE 91017-58-2 ADEFOVIR 106941-25-7 ACADESINE 2627-69-2 ADELMIDROL 1675-66-7 ACAMPROSATE 77337-76-9 ADEMETIONINE 17176-17-9 ACAPRAZINE 55485-20-6 ADENOSINE PHOSPHATE 61-19-8 ACARBOSE 56180-94-0 ADIBENDAN 100510-33-6 ACEBROCHOL 514-50-1 ADICILLIN 525-94-0 ACEBURIC ACID 26976-72-7 ADIMOLOL 78459-19-5 ACEBUTOLOL 37517-30-9 ADINAZOLAM 37115-32-5 ACECAINIDE 32795-44-1 ADIPHENINE 64-95-9 ACECARBROMAL 77-66-7 ADIPIODONE 606-17-7 ACECLIDINE 827-61-2 ADITEREN 56066-19-4 ACECLOFENAC 89796-99-6 ADITOPRIM 56066-63-8 ACEDAPSONE 77-46-3 ADOSOPINE 88124-26-9 ACEDIASULFONE SODIUM 127-60-6 ADOZELESIN 110314-48-2 ACEDOBEN 556-08-1 ADRAFINIL 63547-13-7 ACEFLURANOL 80595-73-9 ADRENALONE
    [Show full text]
  • Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017
    Q UO N T FA R U T A F E BERMUDA PHARMACY AND POISONS (THIRD AND FOURTH SCHEDULE AMENDMENT) ORDER 2017 BR 111 / 2017 The Minister responsible for health, in exercise of the power conferred by section 48A(1) of the Pharmacy and Poisons Act 1979, makes the following Order: Citation 1 This Order may be cited as the Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017. Repeals and replaces the Third and Fourth Schedule of the Pharmacy and Poisons Act 1979 2 The Third and Fourth Schedules to the Pharmacy and Poisons Act 1979 are repealed and replaced with— “THIRD SCHEDULE (Sections 25(6); 27(1))) DRUGS OBTAINABLE ONLY ON PRESCRIPTION EXCEPT WHERE SPECIFIED IN THE FOURTH SCHEDULE (PART I AND PART II) Note: The following annotations used in this Schedule have the following meanings: md (maximum dose) i.e. the maximum quantity of the substance contained in the amount of a medicinal product which is recommended to be taken or administered at any one time. 1 PHARMACY AND POISONS (THIRD AND FOURTH SCHEDULE AMENDMENT) ORDER 2017 mdd (maximum daily dose) i.e. the maximum quantity of the substance that is contained in the amount of a medicinal product which is recommended to be taken or administered in any period of 24 hours. mg milligram ms (maximum strength) i.e. either or, if so specified, both of the following: (a) the maximum quantity of the substance by weight or volume that is contained in the dosage unit of a medicinal product; or (b) the maximum percentage of the substance contained in a medicinal product calculated in terms of w/w, w/v, v/w, or v/v, as appropriate.
    [Show full text]
  • Reference Table for Scabies Treatment Permethrin and Crotamiton Products Are Commonly Used Over-The-Counter Products That Are FDA Approved Treatments for Scabies
    Reference Table for Scabies Treatment Permethrin and crotamiton products are commonly used over-the-counter products that are FDA approved treatments for scabies. Invermectin is an FDA approved treat- ment that is available by prescription in both an oral medication and a lotion. Lindane is FDA approved for scabies but is no longer recommended as a first-line treatment for scabies due to its potential CNS toxicity. Brand Chemical FDA Approved Dosage Side Effects Precautions Name Name Use Nix, Elimite, 5% Permethrin FDA approved for Apply 5% cream from neck Treatment may initially Do not get into eyes, nose, or mouth Generic cream treatment of sca- down over entire body pay- make redness, swell- If pregnant or breast feeding, consult health care pro- bies. For use in chil- ing special attention to all ing, or itching worse. vider for instructions if using treatment on self or chil- dren 2 months of folds and creases. Wash Tingling or numbness. dren. age and older. off thoroughly after 8-14 Notify health care provider of pre-existing illness or hours. Second application allergies. is advised after 7 days. Do not use if sensitive to ragweed or chrysanthemums. Eurax, 10% Crotamiton FDA approved for Apply 10% cream from Irritation and itching Do not get into eyes, nose or mouth Crotan cream or lotion treatment of sca- chin down over entire body If pregnant or breast feeding, consult health care pro- bies. For use in chil- paying special attention to vider for instructions if using treatment on self or chil- dren 6 months of all folds and creases.
    [Show full text]
  • WO 2011/156817 Al
    (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date Χ t it o n 1 15 December 2011 (15.12.2011) WO 2011/156817 Al (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every C02F1/58 (2006.01) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, (21) International Application Number: CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, PCT/US20 11/040214 DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, 13 June 201 1 (13.06.201 1) KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, (25) Filing Language: English NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, (26) Publication Language: English SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: 61/354,031 11 June 2010 ( 11.06.2010) (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (71) Applicant (for all designated States except US): MOLY- GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, CORP MINERALS LLC [US/US]; 561 Denver Tech ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, MD, RU, TJ, Center Pkwy, Suite 1000, Greenwood Village, CO 801 11 TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, (US).
    [Show full text]
  • PRODUCT INFORMATION Buclizine (Hydrochloride) Item No
    PRODUCT INFORMATION Buclizine (hydrochloride) Item No. 25641 CAS Registry No.: 129-74-8 Formal Name: 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1- dimethylethyl)phenyl]methyl]-piperazine, dihydrochloride Synonym: NSC 25141 MF: C H ClN • 2HCl 28 33 2 N FW: 506.0 Purity: ≥98% N Cl UV/Vis.: λmax: 224, 279 nm Supplied as: A crystalline solid • 2HCl Storage: -20°C Stability: ≥2 years Information represents the product specifications. Batch specific analytical results are provided on each certificate of analysis. Laboratory Procedures Buclizine (hydrochloride) is supplied as a crystalline solid. A stock solution may be made by dissolving the buclizine (hydrochloride) in the solvent of choice. Buclizine (hydrochloride) is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide, which should be purged with an inert gas. The solubility of buclizine (hydrochloride) in these solvents is approximately 0.11, 0.17, and 5 mg/ml, respectively. Description Buclizine is an antihistamine.1 It reduces bronchoconstriction and lethality induced by aerosolized histamine in guinea pigs when administered at a dose of 1 mg/kg. Buclizine (40-200 mg/kg) induces gross malformations, including fusion of the tongue to the palate, cleft palate, micrognathia, and micromelia, and bone malformations in rats.2 It also inhibits cancer cell growth by binding to translationally controlled tumor protein (TCTP) and inducing cell differentiation.3 Formulations containing buclizine have been used to treat nausea induced by pregnancy and motion sickness. References 1. Schiller, I.W. and Lowell, F.C. Toxicologic and clinical appraisal of buclizine, a new antihistaminic compound. J. Allergy 27(1), 63-67 (1956).
    [Show full text]