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92 H. ISBELL & T. L. CHRUSCIEL

366. Stockings, G. T. (1940) J. ment. Sci., 86, 29 (A 368. Unger, S. M. (1963) Psychiatry, 26, 111-125 clinical study of the psychosis with (Mescaline, LSD, and personality special reference to the mechanism of the genesis change) of schizophrenia and other psychotic states) 369. Wolbach, A. B., Isbell, H. & Miner, E. J. (1962) 367. Thale, T., Gabrio, B. W. & Solomon, K. (1950) Psychopharmacologia (Ber.), 3, 1 (Cross- Amer. J. Psychiat., 106, 686-691 (Hallucinations tolerance between mescaline and LSD-25 with a and imagery by mescaline) comparison of the mescaline and LSD reactions)

HALLUCINOGENIC

As explained above, the subjective reaction to 373. Innes, I. R. & Nickerson, M. (1965) In: Goodman, these (Table XVIII) is dysphoric and not L. S. & Gilman, A., ed., The pharmacological euphoric, and, although persons prone to basis of therapeutics, 3rd ed., pp. 521-545, dependence may try them once, they do not do so a Macmillan Co., New York (Drugs inhibiting the action of on structures innervated second time. Accordingly, their abuse potential is by postganglionic parasympathetic nerves (anti- very low or non-existent even though their psycho- muscarinic or atropinic drugs)) toxicity is quite high. 374. Isbell, H., Rosenberg, D. E., Miner, E. J. & Some of the antihistamines and benactyzine can, Logan, C. R. (1964) Neuropsychopharmacology, in high dose or in very susceptible persons, cause an 3, 440-446 (Tolerance and cross-tolerance to -like psychosis."' 370, 371 , N-ethyl-3-piperidyl benzilate (JB- 318) and LSD-25) 375. Lewin, L. (1964) Phantastica. Narcotic and stimulat- REFERENCES ing drugs [Translation from German] Routledge 370. Banshikov, V. M. & Stolarov, G. V. (1966) Zh. and Kegan Paul, London Nevropat. Psikhiat., 66, 464-468 (Psychotomime- 376. Pfeiffer, C. C. & Murphree, H. B. (1965) In: tic substances with action) DiPalma, J. R., ed., Drill's pharmacology in 371. Fink, M. & Itil, T. (1968) In: Efron, D. H., ed., medicine, 3rd ed., pp. 321-336, McGraw-Hill, Psychopharmacology. A review of progress New York (Chapter 22, Introduction to psycho- 1957-1967, pp. 1231-1239, Public Health Service tropic and hallucinogenic drugs) Publication No. 1836, US Government Printing 377. Vojt&hovsky, D., Krus, S., Grof, S., Vitek, V., Office, Washington, D.C. (Neurophysiology of Rysanek, K., Kunz, K. & Skala, J. (1967) In: phantastica: EEG and behavioral relations in Brill, H., ed., Neuro-psycho-pharmacology, pp. man) 388-389, Excerpta Medica Foundation, Amster- 372. Haen, P. de (1964) Drugs in research, P. de Haen, dam (Experimental psychoses induced by New York benactyzine in alcoholics) C' 0 0 U 0 C._ 0 C-' 0 C lO E00 It 0 0 z 4)0 r- 6 11 X< cocO E oZ 0 0z- M C U 0 z _ e ._

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