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Meet the Faculty Candidates MEET THE FACULTY CANDIDATES Specialty - Biomaterials Alessia Battigelli Woo-Sik Jang Sejin Son John Clegg Patrick Jurney Young Hye Song R. Cornelison Kevin McHugh Ryan Stowers Yonghui Ding Yifeng Peng Varadraj Vernekar Victor Hernandez-Gordillo Shantanu Pradhan Scott Wilson Marian Hettiaratchi Eiji Saito Yaoying Wu Era Jain Andrew Shoffstall Specialty - Biomechanics Adam Abraham Vince Fiore Panagiotis Mistriotis Edward Bonnevie Zeinab Hajjarian Simone Rossi Alexander Caulk Xiao Hu Alireza Yazdani Venkat Keshav Chivukula Heidi Kloefkorn Rana Zakerzadeh Jacopo Ferruzzi Yizeng Li Specialty - Biomedical Imaging Mahdi Bayat Chong Huang Katheryne Wilson Zhichao Fan Jingfei Liu Kihwan Han Alexandra Walsh Specialty - BioMEMS Jaehwan Jung Aniruddh Sarkar Mengxi Wu Specialty - Cardiovascular Engineering Reza Avaz Kristin French Zhenglun (Alan) Wei Specialty - Cellular Engineering Annie Bowles Kate Galloway Kuei-Chun Wang Alexander Buffone Laurel Hind Mahsa Dabagh Matthew Kutys See other side for more candidates Specialty - Device Engineering (Microfluidics, Electronics, Machine-Body interface) Taslim Al-Hilal Brian Johnson David Myers Jungil Choi Tae Jin Kim Max Villa Haishui Huang Jiannan Li Ying Wang Specialty - Drug Delivery Heather Gustafson John Martin Teng Su Specialty - Molecular Engineering/Biophysics Felipe Garcia Quiroz Jae Kyoo Lee Dibyendu Sasmal Specialty - Nanotechnology Sambeeta Das Soumik Siddhanta Kevin Yehl Zeinab Jahed Aniket Wadajkar Brian Meckes Alexander Xu Specialty - Neural Engineering Tyler Clites Shaoyu Qiao Or Shemesh Melanie Ecker Adam Rouse Jerzy Szablowski Matthew Hemphill Debajit Saha Specialty - Synthetic Biology Nichole Daringer Xiaojing Gao Mark Mimee Joseph Decker George Lu Specialty - Systems/Computational Biology SepidehDolatshahi Chris Kieslich Kaitlin Fogg Xiao Ma Specialty - Tissue Engineering/Regenerative Medicine Ramkumar Annamalai Jesse Placone Bo Ri Seo Derfogail Delcassian Shreya Raghavan Halil Tekin Jonathan Grasman Kaitlyn Sadtler Olaia Vila Vivian Lee Marco Santoro Joshua Zimmermann Neil Lin Nicholas Schaub Jonathan Zuidema Adam Mellott Rebecca Scott Specialty - Not Specified Suman Bose Seung Yup Lee Xulei Qin Joseph Chen Mark Mondrinos Hua Wang Taisuke Kojima Jutaek Nam ADAM C. ABRAHAM, PhD Orthopedic Surgery, Columbia University, 390 Fort Washington Ave, #6E, New York, NY, 10033 [email protected] Research Overview: My multi-disciplinary background spans the fields of mechanical and biomedical engineering with additional training in metabolic diseases and immunology. My research expertise includes multi-scale biomechanics, inflammation, and musculoskeletal disease modeling. Specifically, my research is focused on how musculoskeletal joint structure and function is regulated by inflammatory signaling and uses surgical and genetic murine models of human disease, molecular biology, and multi-scale mechanics for applications in exercise adaptation, osteoarthritis, and intervertebral disc disease. Education: Ph.D. Mechanical Engineering, 2013, Colorado State University, Fort Collins, CO M.S. Mechanical Engineering, 2009, Michigan Technological University, Houghton, MI B.S. Mechanical Engineering, 2006, Michigan Technological University, Houghton, MI Research/Work Experience: • Post-doctoral Research Scientist (2016 – present) Carroll Laboratories for Orthopedic Surgery, Advisor: Stavros Thomopoulos, Department of Orthopedic Surgery at Columbia University • Visiting Research Scholar (July / August 2017) Institute of Infection, Immunity & Inflammation, Advisors: Neal Millar & Stavros Thomopoulos), College of Medical, Veterinary & Life Sciences at the University of Glasgow • NIH T32 Metabolic Skeletal Disorders Post-Doctoral Trainee (2013 – 2015) Musculoskeletal Research Center, Advisors: Simon Y. Tang, Matthew Silva, Linda Sandell, Departments of Orthopedic Surgery & Bone and Mineral Diseases at Washington University in St. Louis • NIH F31 Pre-doctoral Research Fellow (2011 – 2013) Soft Tissue Mechanics Laboratory, Advisor: Tammy Haut Donahue, Colorado State University • Graduate Research Assistant (2009 – 2013) Soft Tissue Mechanics Laboratory, Advisor: Tammy Haut Donahue, Colorado State University • Graduate Research Assistant (2007 – 2008) Dynamic Signal Processing Laboratory, Advisor: Jason Blough, Michigan Technological University • Noise & Vibration Engineering Intern (Summer 2006) American Axle Mfg Engineering Technician (May 2000 – September 2005) Raven Engineering Inc. Selected Publications: 1. Abraham, A.C., Shah, S.A., Golman, M., Song, L., Li, X., Kurtaliaj, I., Akbar, M., Millar, N.L., Abu-Amer, Y., Galatz, L.M., Thomopoulous, S. IKKβ:NF-kB activation in chronic tendon disease: targeting the stroma. In Review 2. Abraham, A.C., Liu J.W. & Tang, S.Y. Longitudinal changes in the structure and inflammatory response of the intervertebral disc due to stab injury in a murine organ culture model. Journal of Orthopaedic Research. 2016. 34(8): 1431-8 3. Abraham, A.C, Agarawalla, A., Yadavalli, A., Liu, Y.J. & Tang, S.Y. Multiscale Predictors of Femoral Neck in situ Strength in Elderly Women: Contributions of BMD, Cortical Porosity, Reference Point Indentation, and Nonenzymatic Glycation. Journal of Bone & Mineral Research. 2015, 30(12): 2207-2214 4. Abraham, A.C., Pauly, H.M. & Haut Donahue, T.L. Deleterious effects of osteoarthritis on the Structure and Function of Human Meniscal Attachments. Osteoarthritis and Cartilage, 2014, 22(2): 275-283 5. Abraham, A.C. & Haut Donahue, T.L. From Meniscus to Bone: A Quantitative Study of Structure and Function of the Human Meniscal Attachments. Acta Biomaterialia, 2013, 9(5):6322-9 Awards/Honors: Columbia Univ./Univ. of Glasgow Research Exchange Award, 2017 Philadelphia Spine Research Society Meeting, 1st Place Poster, Biomechanics, 2015 R.L. Kirschstein National Research Service Award Institutional Fellowship (T32), 2013 – 2015 R.L. Kirschstein National Research Service Award Pre-Doctoral Fellowship (F31), 2011 – 2013 Michigan Space Grant Consortium Graduate Fellowship, 2010 TASLIM AHMED AL-HILAL, PhD Pharmacy, Texas Tech university Health Sciences Center, 1300 Coulter Dr, Amarillo, Texas, 79106 [email protected] Research Overview: Deregulated angiogenesis or disorders of the vasculature contribute to numerous malignant, cardiovascular, or lung diseases. Molecular insight into these processes has generated new therapeutic opportunities, but controlled and site-specific regulation of a molecular signaling pathway remains a major challenge to current vascular-targeting therapies, i.e anti-angiogenic drugs indiscriminately target both physiological (good) and pathological (bad) vasculature. Thus, with a goal to identify a new molecular target that is only expressed in diseased but not healthy vessels, I discovered that a prion-like protein, doppel, is selectively expressed in pathological angiogenesis such as tumor-related, but not in normal vasculature. Animal and cellular models have been also instrumental in understanding the process of many vascular diseases, but they fail to recapitulate the human physiology. On the other hand, experimental models of blood vessels (organ-on-a-chip) are of great importance for understanding the pathophysiology of angiogenesis-dependent diseases, for screening purposes and for development of new and improved therapeutics and diagnostics. Thus, to create experimental systems recapitulating tissue- and organ-level physiology of blood vessels in-vitro, I have deployed the state-of-the-art microfluidic technology and developed a tissue-on-a-chip model, mimicking a multimodal complex disease afflicting pulmonary arteries, pulmonary arterial hypertension (PAH). Thus, my research interest focuses to explore the role of doppel, develop doppel-targeted therapeutics, and deploy microfluidic-based new tools to screen and identify new targets involved in vascular pathologies. Education: Ph.D., 2014; Seoul National University, Seoul, South Korea MS, 2010; Seoul National University, Seoul, South Korea B.Pharm, 2006; University of Development Alternative, Dhaka, Bangladesh Research/Work Experience: 2015-Present, Post-doctoral Research Associate, School of Pharmacy, Texas Tech University Health Sciences Center 2014-2015, Research Scientist, Center for Theragnosis, Korea Institute of Science and Technology Selected Publications: 1. Al-Hilal TA, Keshavarz A, Lahooti B, Kadry H, Zhenya D, Li W, Kamm R, McMurtry IF, Lahm T, Nozik-Grayck E, Stenmark KR, and Ahsan F A microfluidic tissue chip recapitulating human pulmonary arterial hypertension: Fabrication, validation and application. Science Translational Medicine, 2018; Under Revision: article submitted in 25-July’2018 and received a revision letter in 28-August’2018. 2. Al-Hilal TA, Chung SW, Choi JW, Alam F, Park J, Kim SW, Kim SY, Ahsan F, Kim I-S*, Byun Y*. Targeting prion-like protien doppel selectively suppresses tumor angiogenesis. The Journal of Clinical Investigation, 2016; 126(4):1251-1266. 3. Al-Hilal TA, Chung SW, Alam F, Park J, Lee KE, Jeon H, Kim K, Kwon IC, Kim I-S, Kim SY, Byun Y. Functional transformations of bile acid transporters induced by high-affinity macromolecules. Scientific Reports, 2014; 4:4163. 4. Al-Hilal TA, Alam F, Byun Y. Oral drug delivery systems using chemical conjugates or physical complexes. Advanced Drug Delivery Reviews, 2013; 65(6):845-864. 5. Seo J, Al-Hilal TA, Jee JG, Kim YL, Kim HJ, Lee BH, Kim S, Kim IS. A targeted ferritin-microplasmin based thrombolytic nanocage selectively dissolves blood clots. Nanomedicine: nanotechnology,
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