Royal Free Hospital Drug Formulary

Title Formulary Status Section Annotation 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse ABACAVIR On Formulary transcriptase inhibitors As per HIV guidelines. AbidecÂ® On Formulary 9.6 Vitamins‐>9.6.7 Multivitamin preparations 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Anti‐ ABIRATERONE ACETATE On Formulary androgens 4.10 Drugs used in substance dependence‐>4.10.1 Alcohol ACAMPROSATE CALCIUM On Formulary dependence‐>Acamprosate 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other ACARBOSE On Formulary antidiabetic drugs 11.6 Treatment of glaucoma‐>Carbonic anhydrase inhibitors and ACETAZOLAMIDE On Formulary systemic drugs 11.8 Miscellaneous ophthalmic preparations‐>11.8.2 Ocular diagnostic and peri‐operative preparations and photodynamic ACETYLCHOLINE CHLORIDE On Formulary treatment‐>Ocular peri‐operative drugs ACETYLCYSTEINE On Formulary Specific drugs‐>Analgesics (non‐opioid) Acetylcysteine On Formulary Specific drugs‐>Analgesics (non‐opioid)‐>ACETYLCYSTEINE 11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, ACETYLCYSTEINE On Formulary ocular lubricants, and astringents ACICLOVIR On Formulary 11.3 Anti‐infective eye preparations‐>11.3.3 Antivirals

ACICLOVIR On Formulary 13.10 Anti‐infective skin preparations‐>13.10.3 Antiviral preparations 13.10 Anti‐infective skin preparations‐>13.10.3 Antiviral preparations‐ Aciclovir On Formulary >ACICLOVIR 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for ACITRETIN On Formulary psoriasis‐>Oral retinoids for psoriasis Removal and elimination‐>Removal from the gastro‐intestinal tract‐ Actidose‐AquaÂ® Advance On Formulary >CHARCOAL, ACTIVATED 6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and other drugs affecting bone metabolism‐>Bisphosphonates‐ Actonel Once a WeekÂ® On Formulary >RISEDRONATE SODIUM 6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and other drugs affecting bone metabolism‐>Bisphosphonates‐ ActonelÂ® On Formulary >RISEDRONATE SODIUM 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other ActosÂ® On Formulary antidiabetic drugs‐>PIOGLITAZONE 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.1 Short‐acting ActrapidÂ® On Formulary insulins‐>INSULIN‐>Human sequence Insulin Sliding Scale

4.7 Analgesics‐>4.7.1 Non‐opioid analgesics and compound analgesic AcupanÂ® On Formulary preparations‐>NEFOPAM HYDROCHLORIDE

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ AdalatÂ® On Formulary >2.6.2 Calcium‐channel blockers‐>NIFEDIPINE

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ AdalatÂ® LA On Formulary >2.6.2 Calcium‐channel blockers‐>NIFEDIPINE‐>Modified release Only 20mg and 30mg tablets stocked.

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ AdalatÂ® Retard On Formulary >2.6.2 Calcium‐channel blockers‐>NIFEDIPINE‐>Modified release 13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐>Topical ADAPALENE On Formulary retinoids and related preparations for acne

10.1 Drugs used in rheumatic diseases and gout‐>10.1.2 Corticosteroids‐>10.1.2.2 Local corticosteroid injections‐>LOCAL AdcortylÂ® Intra‐articular/Intradermal On Formulary CORTICOSTEROID INJECTIONS‐>Triamcinolone acetonide AddiphosÂ® On Formulary 9.3 Intravenous nutrition‐>Supplementary preparations AdditraceÂ® On Formulary 9.3 Intravenous nutrition‐>Supplementary preparations 2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ AdenocorÂ® On Formulary >Supraventricular arrhythmias‐>ADENOSINE 2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ ADENOSINE On Formulary >Supraventricular arrhythmias Administration of drugs via inhalers Administration of drugs for asthma On Formulary 3.1 Bronchodilators‐>Asthma guideline

ADRENALINE/EPINEPHRINE On Formulary 2.7 Sympathomimetics‐>2.7.3 Cardiopulmonary resuscitation 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ ADRENALINE/EPINEPHRINE On Formulary >3.4.3 Allergic emergencies‐>Anaphylaxis Adrenaline/Epinephrine 1 in 10â€‰000, 2.7 Sympathomimetics‐>2.7.3 Cardiopulmonary resuscitation‐ Dilute On Formulary >ADRENALINE/EPINEPHRINE 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ Adrenaline/Epinephrine 1 in 10â€‰000, >3.4.3 Allergic emergencies‐>Anaphylaxis‐ Dilute On Formulary >ADRENALINE/EPINEPHRINE‐>Intravenous

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.3 Allergic emergencies‐>Anaphylaxis‐ Adrenaline/Epinephrine 1 in 1000 On Formulary >ADRENALINE/EPINEPHRINE‐>Intramuscular or subcutaneous Administration of drugs via inhalers Adrenoceptor agonists On Formulary 3.1 Bronchodilators guideline

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

14.4 Vaccines and antisera‐>Diphtheria vaccines‐>DIPHTHERIA‐ Adsorbed Diphtheria [low dose], Tetanus and CONTAINING VACCINES‐>Diphtheria‐containing vaccines for children Poliomyelitis (Inactivated) Vaccine On Formulary over 10 years and adults

Adsorbed Diphtheria [low dose], Tetanus, 14.4 Vaccines and antisera‐>Diphtheria vaccines‐>DIPHTHERIA‐ Pertussis (Acellular, Component) and CONTAINING VACCINES‐>Diphtheria‐containing vaccines for children Poliomyelitis (Inactivated) Vaccine On Formulary under 10 years Adsorbed Diphtheria, Tetanus, Pertussis 14.4 Vaccines and antisera‐>Diphtheria vaccines‐>DIPHTHERIA‐ (Acellular, Component) and Poliomyelitis CONTAINING VACCINES‐>Diphtheria‐containing vaccines for children (Inactivated) Vaccine On Formulary under 10 years 3.1 Bronchodilators‐>3.1.5 Peak flow meters, inhaler devices and AeroChamberÂ® Plus On Formulary nebulisers‐>Drug delivery devices 9.8 Metabolic disorders‐>9.8.1 Drugs used in metabolic disorders‐ AGALSIDASE ALFA and BETA On Formulary >Fabry's disease

3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective AiromirÂ® On Formulary beta2 agonists‐>SALBUTAMOL‐>Inhalation

9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid ALBUMIN SOLUTION On Formulary and electrolyte imbalance‐>9.2.2.2 Plasma and plasma substitutes Available via the blood bank

6.1 Drugs used in diabetes‐>6.1.6 Diagnostic and monitoring devices AlbustixÂ® On Formulary for diabetes mellitus‐>Urinalysis‐>Protein 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.1 ALCOHOL On Formulary Alcohols and saline

2.2 Diuretics‐>2.2.3 Potassium‐sparing diuretics and aldosterone AldactoneÂ® On Formulary antagonists‐>Aldosterone antagonists‐>SPIRONOLACTONE 13.7 Preparations for warts and calluses‐>Anogenital warts‐ AldaraÂ® On Formulary >IMIQUIMOD 8.2 Drugs affecting the immune response‐>8.2.4 Other Aldesleukin On Formulary immunomodulating drugs 2.5 Hypertension and heart failure‐>2.5.2 Centrally acting AldometÂ® On Formulary antihypertensive drugs‐>METHYLDOPA

6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and ALENDRONIC ACID On Formulary other drugs affecting bone metabolism‐>Bisphosphonates 6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and other drugs affecting bone metabolism‐>Bisphosphonates‐ Alendronic acid On Formulary >ALENDRONIC ACID ALFACALCIDOL On Formulary 9.6 Vitamins‐>9.6.4 Vitamin D Alfacalcidol On Formulary 9.6 Vitamins‐>9.6.4 Vitamin D‐>ALFACALCIDOL 15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ ALFENTANIL On Formulary operative drugs‐>15.1.4.3 Opioid analgesics Controlled Drug Requirements 7.4 Drugs for genito‐urinary disorders‐>7.4.1 Drugs for urinary ALFUZOSIN HYDROCHLORIDE On Formulary retention‐>Alpha‐blockers 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.1 Antihistamines‐>Sedating antihistamines‐>ALIMEMAZINE Alimemazine On Formulary TARTRATE

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ ALIMEMAZINE TARTRATE On Formulary >3.4.1 Antihistamines‐>Sedating antihistamines AlkeranÂ® On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs‐>MELPHALAN

10.1 Drugs used in rheumatic diseases and gout‐>10.1.4 Gout and ALLOPURINOL On Formulary cytotoxic‐induced hyperuricaemia‐>Long‐term control of gout 10.1 Drugs used in rheumatic diseases and gout‐>10.1.4 Gout and cytotoxic‐induced hyperuricaemia‐>Long‐term control of gout‐ Allopurinol On Formulary >ALLOPURINOL Almond Oil On Formulary 12.1 Drugs acting on the ear‐>12.1.3 Removal of earwax

11.4 Corticosteroids and other anti‐inflammatory preparations‐ AlomideÂ® On Formulary >11.4.2 Other anti‐inflammatory preparations‐>LODOXAMIDE Tocopheryl acetate 100mg/2ml ALPHA TOCOPHERYL ACETATE On Formulary 9.6 Vitamins‐>9.6.5 Vitamin E injection also kept at the RFH. 13.4 Topical corticosteroids‐>HYDROCORTISONE‐>Compound AlphadermÂ® On Formulary preparations 11.6 Treatment of glaucoma‐>Sympathomimetics‐>BRIMONIDINE AlphaganÂ® On Formulary TARTRATE 13.9 Shampoos and other preparations for scalp and hair conditions‐ Alphosyl 2 in 1Â® On Formulary >Shampoos

1.1 Dyspepsia and gastro‐oesophageal reflux disease‐>1.1.1 Antacids and simeticone‐>Aluminium‐ and magnesium‐containing antacids‐ Alu‐CapÂ® On Formulary >ALUMINIUM HYDROXIDE‐>Aluminium‐only preparations 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Astringent ALUMINIUM ACETATE On Formulary preparations 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Astringent Aluminium Acetate On Formulary preparations‐>ALUMINIUM ACETATE

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

1.1 Dyspepsia and gastro‐oesophageal reflux disease‐>1.1.1 Antacids ALUMINIUM HYDROXIDE On Formulary and simeticone‐>Aluminium‐ and magnesium‐containing antacids ALUMINIUM SALTS On Formulary 13.12 Hyperhidrosis

4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 AMANTADINE HYDROCHLORIDE On Formulary Dopaminergic drugs used in Parkinson's disease‐>Amantadine AmetopÂ® On Formulary 15.2 Local anaesthesia‐>Tetracaine‐>TETRACAINE 2.2 Diuretics‐>2.2.3 Potassium‐sparing diuretics and aldosterone Amiloride On Formulary antagonists‐>AMILORIDE HYDROCHLORIDE 2.2 Diuretics‐>2.2.3 Potassium‐sparing diuretics and aldosterone AMILORIDE HYDROCHLORIDE On Formulary antagonists AMINOPHYLLINE On Formulary 3.1 Bronchodilators‐>3.1.3 Theophylline Aminophylline On Formulary 3.1 Bronchodilators‐>3.1.3 Theophylline‐>AMINOPHYLLINE 2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ >Supraventricular and ventricular arrhythmias‐>AMIODARONE Amiodarone On Formulary HYDROCHLORIDE 2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ AMIODARONE HYDROCHLORIDE On Formulary >Supraventricular and ventricular arrhythmias

4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant Amitriptyline On Formulary drugs‐>Tricyclic antidepressants‐>AMITRIPTYLINE HYDROCHLORIDE 4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant AMITRIPTYLINE HYDROCHLORIDE On Formulary drugs‐>Tricyclic antidepressants 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ AMLODIPINE On Formulary >2.6.2 Calcium‐channel blockers

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Amlodipine On Formulary >2.6.2 Calcium‐channel blockers‐>AMLODIPINE 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.3 Broad‐spectrum AMOXICILLIN On Formulary penicillins 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.3 Broad‐spectrum Amoxicillin On Formulary penicillins‐>AMOXICILLIN 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.3 Broad‐spectrum AmoxilÂ® On Formulary penicillins‐>AMOXICILLIN AMPHOTERICIN On Formulary 5.2 Antifungal drugs‐>5.2.3 Polyene antifungals

9.1 Anaemias and some other blood disorders‐>9.1.4 Drugs used in ANAGRELIDE On Formulary platelet disorders‐>Essential thrombocythaemia RFH Guidelines for Acute Pain Analgesics On Formulary Management in Adults

8.3 Sex hormones and hormone antagonists in malignant disease‐ ANASTROZOLE On Formulary >8.3.4 Hormone antagonists‐>8.3.4.1 Breast cancer

6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists‐>Anti‐ AndrocurÂ® On Formulary androgens‐>Cyproterone acetate‐>CYPROTERONE ACETATE 15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ >Depolarising neuromuscular blocking drugs‐>SUXAMETHONIUM AnectineÂ® On Formulary CHLORIDE 4.10 Drugs used in substance dependence‐>4.10.1 Alcohol AntabuseÂ® On Formulary dependence‐>Disulfiram‐>DISULFIRAM 1.3 Antisecretory drugs and mucosal protectants‐>1.3.3 Chelates and AntepsinÂ® On Formulary complexes‐>SUCRALFATE

14.5 Immunoglobulins‐>14.5.3 Anti‐D (Rh0) immunoglobulin‐>ANTI‐D Not available through pharmacy ‐ Anti‐D (Rh0) Immunoglobulin On Formulary (Rh0) IMMUNOGLOBULIN obtain from the blood bank. 13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐>Topical ANTIBACTERIALS On Formulary antibacterials for acne Anticoagulants and protamine On Formulary Anticoagulation guidelines

1.7 Local preparations for anal and rectal disorders‐>1.7.2 Compound Anusol‐HCÂ® On Formulary haemorrhoidal preparations with corticosteroids

4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor APO‐goÂ® On Formulary agonists‐>APOMORPHINE HYDROCHLORIDE 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor APOMORPHINE HYDROCHLORIDE On Formulary agonists 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator ApresolineÂ® On Formulary antihypertensive drugs‐>HYDRALAZINE HYDROCHLORIDE 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐ AquadrateÂ® On Formulary >Preparations containing urea

13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐>13.2.1.1 Aqueous Cream, BP On Formulary Emollient bath and shower preparations 6.2 Thyroid and antithyroid drugs‐>6.2.2 Antithyroid drugs‐>IODINE Aqueous Iodine Oral Solution On Formulary AND IODIDE

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Drugs affecting the immune AravaÂ® On Formulary response‐>LEFLUNOMIDE 6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and other drugs affecting bone metabolism‐>Bisphosphonates‐ Aredia Dry PowderÂ® On Formulary >PAMIDRONATE DISODIUM AriceptÂ® On Formulary 4.11 Dementia‐>DONEPEZIL HYDROCHLORIDE

8.3 Sex hormones and hormone antagonists in malignant disease‐ ArimidexÂ® On Formulary >8.3.4 Hormone antagonists‐>8.3.4.1 Breast cancer‐>ANASTROZOLE

8.3 Sex hormones and hormone antagonists in malignant disease‐ AromasinÂ® On Formulary >8.3.4 Hormone antagonists‐>8.3.4.1 Breast cancer‐>EXEMESTANE 4.9 Drugs used in parkinsonism and related disorders‐>4.9.2 Antimuscarinic drugs used in parkinsonism‐>PROCYCLIDINE ArpicolinÂ® On Formulary HYDROCHLORIDE 2.5mg/5ml solution not kept. 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Artemether with ARTEMETHER WITH LUMEFANTRINE On Formulary lumefantrine 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ steroidal anti‐inflammatory drugs‐>DICLOFENAC SODIUM‐>With ArthrotecÂ® On Formulary misoprostol

AsacolÂ® On Formulary 1.5 Chronic bowel disorders‐>1.5.1 Aminosalicylates‐>MESALAZINE

AsacolÂ® MR On Formulary 1.5 Chronic bowel disorders‐>1.5.1 Aminosalicylates‐>MESALAZINE

Ascorbic acid injection not kept at the ASCORBIC ACID On Formulary 9.6 Vitamins‐>9.6.3 Vitamin C RFH. See under thiamine (Pabrinex).

Ascorbic acid injection not kept at the Ascorbic Acid On Formulary 9.6 Vitamins‐>9.6.3 Vitamin C‐>ASCORBIC ACID RFH. See under thiamine (Pabrinex). Aspirin On Formulary 2.9 Antiplatelet drugs‐>ASPIRIN (antiplatelet) 4.7 Analgesics‐>4.7.1 Non‐opioid analgesics and compound analgesic ASPIRIN On Formulary preparations 4.7 Analgesics‐>4.7.1 Non‐opioid analgesics and compound analgesic Aspirin On Formulary preparations‐>ASPIRIN ASPIRIN (antiplatelet) On Formulary 2.9 Antiplatelet drugs 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.1 Antihistamines‐>Sedating antihistamines‐>HYDROXYZINE AtaraxÂ® On Formulary HYDROCHLORIDE

ATAZANAVIR On Formulary 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors As per HIV guidelines. Atenolol injection restricted to ATENOLOL On Formulary 2.4 Beta‐adrenoceptor blocking drugs cardiology and ITU only. Atenolol On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>ATENOLOL Royal Free Maternity Unit Guideline Atosiban On Formulary 7.1 Drugs used in obstetrics‐>7.1.3 Myometrial relaxants for Pre‐Term Labour Royal Free Maternity Unit Guideline ATOSIBAN On Formulary 7.1 Drugs used in obstetrics‐>7.1.3 Myometrial relaxants‐>Atosiban for Pre‐Term Labour 15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ >Non‐depolarising neuromuscular blocking drugs‐>ATRACURIUM Atracurium On Formulary BESILATE

15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ ATRACURIUM BESILATE On Formulary >Non‐depolarising neuromuscular blocking drugs 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse transcriptase inhibitors‐>TENOFOVIR DISOPROXIL‐>With efavirenz AtriplaÂ® On Formulary and emtricitabine As per HIV guidelines. 11.5 Mydriatics and cycloplegics‐>Antimuscarinics‐>ATROPINE Atropine 0.5% eye drops are not Atropine On Formulary SULFATE kept. 15.1 General anaesthesia‐>15.1.3 Antimuscarinic drugs‐>ATROPINE Atropine On Formulary SULFATE Atropine 0.5% eye drops are not ATROPINE SULFATE On Formulary 11.5 Mydriatics and cycloplegics‐>Antimuscarinics kept. ATROPINE SULFATE On Formulary 15.1 General anaesthesia‐>15.1.3 Antimuscarinic drugs 3.1 Bronchodilators‐>3.1.2 Antimuscarinic bronchodilators‐ AtroventÂ® On Formulary >IPRATROPIUM BROMIDE 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.3 Broad‐spectrum AugmentinÂ® On Formulary penicillins‐>CO‐AMOXICLAV

12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ AvamysÂ® On Formulary >Corticosteroids‐>FLUTICASONE PROPIONATE‐>Fluticasone furoate 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐ Only Cream available at the Royal AveenoÂ® On Formulary >Proprietary emollient preparations Free Hospital.

13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐>13.2.1.1 AveenoÂ® On Formulary Emollient bath and shower preparations 10.3 Drugs for the treatment of soft‐tissue disorders and topical pain relief‐>10.3.2 Rubefacients, topical NSAIDs, capsaicin, and poultices‐ AxsainÂ® On Formulary >Capsaicin

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

8.2 Drugs affecting the immune response‐>8.2.1 Antiproliferative AZATHIOPRINE On Formulary immunosuppressants 8.2 Drugs affecting the immune response‐>8.2.1 Antiproliferative Azathioprine On Formulary immunosuppressants‐>AZATHIOPRINE 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Drugs affecting the immune AZATHIOPRINE On Formulary response 13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐ AZELAIC ACID On Formulary >Benzoyl peroxide and azelaic acid 8.2 Drugs affecting the immune response‐>8.2.4 Other BACILLUS CALMETTE‐GUÃ‰RIN On Formulary immunomodulating drugs‐>BCG bladder instillation 14.4 Vaccines and antisera‐>BCG vaccines‐>BACILLUS CALMETTE‐ Bacillus Calmette‐GuÃ©rin Vaccine On Formulary GUÃ‰RIN VACCINE‐>Intradermal 10.2 Drugs used in neuromuscular disorders‐>10.2.2 Skeletal muscle BACLOFEN On Formulary relaxants 10.2 Drugs used in neuromuscular disorders‐>10.2.2 Skeletal muscle Baclofen On Formulary relaxants‐>BACLOFEN 12.2 Drugs acting on the nose‐>12.2.3 Nasal preparations for Bactroban NasalÂ® On Formulary infection‐>Nasal staphylococci MRSA screening procedure

11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, Balanced Salt Solution On Formulary ocular lubricants, and astringents‐>SODIUM CHLORIDE

13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐>13.2.1.1 BalneumÂ® On Formulary Emollient bath and shower preparations Beclometasone On Formulary 3.2 Corticosteroids‐>BECLOMETASONE DIPROPIONATE 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ Beclometasone On Formulary >Corticosteroids‐>BECLOMETASONE DIPROPIONATE BECLOMETASONE DIPROPIONATE On Formulary 3.2 Corticosteroids 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ BECLOMETASONE DIPROPIONATE On Formulary >Corticosteroids 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ BeconaseÂ® On Formulary >Corticosteroids‐>BECLOMETASONE DIPROPIONATE BENDROFLUMETHIAZIDE On Formulary 2.2 Diuretics‐>2.2.1 Thiazides and related diuretics 2.2 Diuretics‐>2.2.1 Thiazides and related diuretics‐ Bendroflumethiazide On Formulary >BENDROFLUMETHIAZIDE Benzoin Tincture, Compound, BP On Formulary 3.8 Aromatic inhalations 13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐ BENZOYL PEROXIDE On Formulary >Benzoyl peroxide and azelaic acid 12.3 Drugs acting on the oropharynx‐>12.3.1 Drugs for oral ulceration BENZYDAMINE HYDROCHLORIDE On Formulary and inflammation 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.1 Benzylpenicillin and BENZYLPENICILLIN SODIUM On Formulary phenoxymethylpenicillin

Beta‐CardoneÂ® On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>SOTALOL HYDROCHLORIDE Sotalol injection not kept at the RFH. 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.4 BetadineÂ® On Formulary Iodine‐>POVIDONEâ€“IODINE 11.6 Treatment of glaucoma‐>Beta‐blockers‐>LEVOBUNOLOL Preservative Free, unit dose eye BetaganÂ® On Formulary HYDROCHLORIDE drops are not kept at RFH. 4.6 Drugs used in nausea and vertigo‐>Other drugs for MÃ©niÃ¨re's BETAHISTINE DIHYDROCHLORIDE On Formulary disease 4.6 Drugs used in nausea and vertigo‐>Other drugs for MÃ©niÃ¨re's Betahistine Dihydrochloride On Formulary disease‐>BETAHISTINE DIHYDROCHLORIDE BETAMETHASONE On Formulary 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy 11.4 Corticosteroids and other anti‐inflammatory preparations‐ BETAMETHASONE On Formulary >11.4.1 Corticosteroids BETAMETHASONE ESTERS On Formulary 13.4 Topical corticosteroids 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ BETAMETHASONE SODIUM PHOSPHATE On Formulary inflammatory preparations‐>Corticosteroids 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ BETAMETHASONE SODIUM PHOSPHATE On Formulary >Corticosteroids Betamethasone Valerate On Formulary 13.4 Topical corticosteroids‐>BETAMETHASONE ESTERS BETAXOLOL On Formulary 11.6 Treatment of glaucoma‐>Beta‐blockers

11.4 Corticosteroids and other anti‐inflammatory preparations‐ Betnesol‐NÂ® On Formulary >11.4.1 Corticosteroids‐>BETAMETHASONE‐>With neomycin 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ inflammatory preparations‐>Corticosteroids‐>BETAMETHASONE Betnesol‐NÂ® On Formulary SODIUM PHOSPHATE‐>With antibacterial

12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐infective Betnesol‐NÂ® On Formulary preparations‐>NEOMYCIN SULFATE‐>With corticosteroid 12.2 Drugs acting on the nose‐>12.2.3 Nasal preparations for Betnesol‐NÂ® On Formulary infection

BetnesolÂ® On Formulary 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy‐>BETAMETHASONE 10.1 Drugs used in rheumatic diseases and gout‐>10.1.2 Corticosteroids‐>10.1.2.2 Local corticosteroid injections‐>LOCAL BetnesolÂ® On Formulary CORTICOSTEROID INJECTIONS‐>Betamethasone

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

11.4 Corticosteroids and other anti‐inflammatory preparations‐ BetnesolÂ® On Formulary >11.4.1 Corticosteroids‐>BETAMETHASONE 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ inflammatory preparations‐>Corticosteroids‐>BETAMETHASONE BetnesolÂ® On Formulary SODIUM PHOSPHATE

12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ BetnesolÂ® On Formulary >Corticosteroids‐>BETAMETHASONE SODIUM PHOSPHATE Betnovate‐RDÂ® On Formulary 13.4 Topical corticosteroids‐>BETAMETHASONE ESTERS Only Cream, Ointment and Scalp application available at the Royal Free BetnovateÂ® On Formulary 13.4 Topical corticosteroids‐>BETAMETHASONE ESTERS Hospital. The 0.25% opthalmic suspension is BetopticÂ® On Formulary 11.6 Treatment of glaucoma‐>Beta‐blockers‐>BETAXOLOL not kept at RFH. BettamousseÂ® On Formulary 13.4 Topical corticosteroids‐>BETAMETHASONE ESTERS

14.4 Vaccines and antisera‐>Meningococcal vaccines‐ BexseroÂ® On Formulary >MENINGOCOCCAL VACCINES‐>Meningococcal group B vaccine BEZAFIBRATE On Formulary 2.12 Lipid‐regulating drugs‐>Fibrates Bezafibrate On Formulary 2.12 Lipid‐regulating drugs‐>Fibrates‐>BEZAFIBRATE 2.12 Lipid‐regulating drugs‐>Fibrates‐>BEZAFIBRATE‐>Modified Bezafibrate On Formulary release BezalipÂ® On Formulary 2.12 Lipid‐regulating drugs‐>Fibrates‐>BEZAFIBRATE 2.12 Lipid‐regulating drugs‐>Fibrates‐>BEZAFIBRATE‐>Modified BezalipÂ® Mono On Formulary release 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Anti‐ BICALUTAMIDE On Formulary androgens Biguanides On Formulary 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs 11.6 Treatment of glaucoma‐>Prostaglandin analogues and BIMATOPROST On Formulary prostamides 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.2 Intermediate‐ and BIPHASIC INSULIN ASPART On Formulary long‐acting insulins‐>Biphasic insulins 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.2 Intermediate‐ and BIPHASIC INSULIN LISPRO On Formulary long‐acting insulins‐>Biphasic insulins 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.2 Intermediate‐ and BIPHASIC ISOPHANE INSULIN On Formulary long‐acting insulins‐>Biphasic insulins BISACODYL On Formulary 1.6 Laxatives‐>1.6.2 Stimulant laxatives Bisacodyl On Formulary 1.6 Laxatives‐>1.6.2 Stimulant laxatives‐>BISACODYL BISOPROLOL FUMARATE On Formulary 2.4 Beta‐adrenoceptor blocking drugs

Bisoprolol Fumarate On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>BISOPROLOL FUMARATE

Bladder instillations and urological surgery On Formulary 7.4 Drugs for genito‐urinary disorders Catheter care guidelines 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic BLEOMYCIN On Formulary antibiotics 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic Bleomycin On Formulary antibiotics‐>BLEOMYCIN 6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and other drugs affecting bone metabolism‐>Bisphosphonates‐>SODIUM BonefosÂ® On Formulary CLODRONATE BRIMONIDINE TARTRATE On Formulary 11.6 Treatment of glaucoma‐>Sympathomimetics 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor BROMOCRIPTINE On Formulary agonists 6.7 Other endocrine drugs‐>6.7.1 Bromocriptine and other BROMOCRIPTINE On Formulary dopaminergic drugs 6.7 Other endocrine drugs‐>6.7.1 Bromocriptine and other Bromocriptine On Formulary dopaminergic drugs‐>BROMOCRIPTINE BUDESONIDE On Formulary 1.5 Chronic bowel disorders‐>1.5.2 Corticosteroids BUDESONIDE On Formulary 3.2 Corticosteroids Budesonide On Formulary 3.2 Corticosteroids‐>BUDESONIDE 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ 64 microgram strength only available BUDESONIDE On Formulary >Corticosteroids at the RNTNE 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ Budesonide On Formulary >Corticosteroids‐>BUDESONIDE BUMETANIDE On Formulary 2.2 Diuretics‐>2.2.2 Loop diuretics Bumetanide On Formulary 2.2 Diuretics‐>2.2.2 Loop diuretics‐>BUMETANIDE 15.2 Local anaesthesia‐>Bupivacaine‐>BUPIVACAINE Bupivacaine On Formulary HYDROCHLORIDE 15.2 Local anaesthesia‐>Bupivacaine‐>BUPIVACAINE Bupivacaine and Adrenaline On Formulary HYDROCHLORIDE‐>With adrenaline BUPIVACAINE HYDROCHLORIDE On Formulary 15.2 Local anaesthesia‐>Bupivacaine BUPRENORPHINE On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics Managing opiate addiction 4.10 Drugs used in substance dependence‐>4.10.3 Opioid BUPRENORPHINE On Formulary dependence‐>Opioid substitution therapy 4.10 Drugs used in substance dependence‐>4.10.2 Nicotine BUPROPION HYDROCHLORIDE On Formulary dependence‐>Bupropion 1.2 Antispasmodics and other drugs altering gut motility‐ BuscopanÂ® On Formulary >Antimuscarinics‐>HYOSCINE BUTYLBROMIDE

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

BUSULFAN On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor CABERGOLINE On Formulary agonists 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor Cabergoline On Formulary agonists‐>CABERGOLINE

8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic CaelyxÂ® On Formulary antibiotics‐>DOXORUBICIN HYDROCHLORIDE‐>Lipid formulation

Calcichew‐D3Â® On Formulary 9.6 Vitamins‐>9.6.4 Vitamin D‐>COLECALCIFEROL‐>With calcium 9.5 Minerals‐>9.5.1 Calcium and magnesium‐>9.5.1.1 Calcium CalcichewÂ® On Formulary supplements‐>CALCIUM SALTS‐>Oral preparations 9.5 Minerals‐>9.5.2 Phosphorus‐>9.5.2.2 Phosphate‐binding agents‐ CalcichewÂ® On Formulary >CALCIUM SALTS 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Vitamin D and CALCIPOTRIOL On Formulary analogues 6.6 Drugs affecting bone metabolism‐>6.6.1 Calcitonin and CALCITONIN (SALMON)/SALCATONIN On Formulary parathyroid hormone CALCITRIOL On Formulary 9.6 Vitamins‐>9.6.4 Vitamin D 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Vitamin D and CALCITRIOL On Formulary analogues

Calcium and Ergocalciferol On Formulary 9.6 Vitamins‐>9.6.4 Vitamin D‐>ERGOCALCIFEROL‐>With calcium

9.5 Minerals‐>9.5.1 Calcium and magnesium‐>9.5.1.1 Calcium Calcium Chloride On Formulary supplements‐>CALCIUM SALTS‐>Parenteral preparations 8.1 Cytotoxic drugs‐>Treatment for cytotoxic‐induced side‐effects‐ >Chemotherapy‐induced mucositis and myelosuppression‐>FOLINIC Calcium Folinate On Formulary ACID‐>Calcium folinate

9.5 Minerals‐>9.5.1 Calcium and magnesium‐>9.5.1.1 Calcium Calcium Gluconate On Formulary supplements‐>CALCIUM SALTS‐>Parenteral preparations

9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and electrolyte imbalance‐>9.2.1.1 Oral potassium‐>Management of Calcium ResoniumÂ® On Formulary hyperkalaemia‐>POLYSTYRENE SULFONATE RESINS 9.5 Minerals‐>9.5.1 Calcium and magnesium‐>9.5.1.1 Calcium CALCIUM SALTS On Formulary supplements

CALCIUM SALTS On Formulary 9.5 Minerals‐>9.5.2 Phosphorus‐>9.5.2.2 Phosphate‐binding agents 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐ CalmuridÂ® On Formulary >Preparations containing urea A2.4 Feed supplements‐>A2.4.1 High‐energy supplements‐>A2.4.1.2 CalogenÂ® On Formulary High‐energy supplements: fat 4.10 Drugs used in substance dependence‐>4.10.1 Alcohol Campral ECÂ® On Formulary dependence‐>Acamprosate‐>ACAMPROSATE CALCIUM 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐ CamptoÂ® On Formulary >Topoisomerase I inhibitors‐>IRINOTECAN HYDROCHLORIDE

Canesten HCÂ® On Formulary 13.4 Topical corticosteroids‐>HYDROCORTISONE‐>With antimicrobials 7.2 Treatment of vaginal and vulval conditions‐>7.2.2 Vaginal and Only 1% cream, 200mg Pessaries and vulval infections‐>Fungal infections‐>PREPARATIONS FOR VAGINAL 500mg Pessaries kept at Royal Free CanestenÂ® On Formulary AND VULVAL CANDIDIASIS Hospital 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐infective CanestenÂ® On Formulary preparations‐>CLOTRIMAZOLE 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal CanestenÂ® On Formulary preparations‐>CLOTRIMAZOLE CAPECITABINE On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme CapotenÂ® On Formulary inhibitors‐>CAPTOPRIL

10.3 Drugs for the treatment of soft‐tissue disorders and topical pain Only the 0.075% strength kept at the Capsaicin On Formulary relief‐>10.3.2 Rubefacients, topical NSAIDs, capsaicin, and poultices RFH 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme CAPTOPRIL On Formulary inhibitors 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme Captopril On Formulary inhibitors‐>CAPTOPRIL 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ >Carbamazepine and related antiepileptics‐>CARBAMAZEPINE‐ CarbagenÂ® SR On Formulary >Modified release 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ CARBAMAZEPINE On Formulary >Carbamazepine and related antiepileptics

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ Carbamazepine On Formulary >Carbamazepine and related antiepileptics‐>CARBAMAZEPINE CARBIMAZOLE On Formulary 6.2 Thyroid and antithyroid drugs‐>6.2.2 Antithyroid drugs CARBOCISTEINE On Formulary 3.7 Mucolytics Carbocisteine On Formulary 3.7 Mucolytics‐>CARBOCISTEINE 11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, CARBOMERS On Formulary ocular lubricants, and astringents Removal and elimination‐>Removal from the gastro‐intestinal tract‐ CarbomixÂ® On Formulary >CHARCOAL, ACTIVATED 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Platinum CARBOPLATIN On Formulary compounds 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Platinum Carboplatin On Formulary compounds‐>CARBOPLATIN

CARBOPROST On Formulary 7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics

CardicorÂ® On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>BISOPROLOL FUMARATE 8.1 Cytotoxic drugs‐>Treatment for cytotoxic‐induced side‐effects‐ CardioxaneÂ® On Formulary >Anthracycline side‐effects‐>DEXRAZOXANE 2.5 Hypertension and heart failure‐>2.5.4 Alpha‐adrenoceptor CarduraÂ® On Formulary blocking drugs‐>DOXAZOSIN 11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, CARMELLOSE SODIUM On Formulary ocular lubricants, and astringents 9.8 Metabolic disorders‐>9.8.1 Drugs used in metabolic disorders‐ Paediatric solution not kept at the CarnitorÂ® On Formulary >Carnitine deficiency‐>LEVOCARNITINE RFH. CARTEOLOL HYDROCHLORIDE On Formulary 11.6 Treatment of glaucoma‐>Beta‐blockers CARVEDILOL On Formulary 2.4 Beta‐adrenoceptor blocking drugs Carvedilol On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>CARVEDILOL 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Anti‐ CasodexÂ® On Formulary androgens‐>BICALUTAMIDE 2.5 Hypertension and heart failure‐>2.5.2 Centrally acting Only 25 microgram tablets and the CatapresÂ® On Formulary antihypertensive drugs‐>CLONIDINE HYDROCHLORIDE injection kept at the RFH 4.7 Analgesics‐>4.7.4 Antimigraine drugs‐>4.7.4.2 Prophylaxis of Only 25 microgram tablets and the CatapresÂ® On Formulary migraine‐>CLONIDINE HYDROCHLORIDE injection kept at the RFH

7.4 Drugs for genito‐urinary disorders‐>7.4.4 Bladder instillations and Only Sodium Chloride Uro‐Tainer M CATHETER PATENCY SOLUTIONS On Formulary urological surgery‐>Maintenance of indwelling urinary catheters kept at the RFH

5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and CEFALEXIN On Formulary other beta‐lactams‐>5.1.2.1 Cephalosporins

5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and Cefalexin On Formulary other beta‐lactams‐>5.1.2.1 Cephalosporins‐>CEFALEXIN

5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and CEFUROXIME On Formulary other beta‐lactams‐>5.1.2.1 Cephalosporins

5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and Cefuroxime On Formulary other beta‐lactams‐>5.1.2.1 Cephalosporins‐>CEFUROXIME

8.2 Drugs affecting the immune response‐>8.2.1 Antiproliferative CellCeptÂ® On Formulary immunosuppressants‐>MYCOPHENOLATE MOFETIL

11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, CelluviscÂ® On Formulary ocular lubricants, and astringents‐>CARMELLOSE SODIUM‐>Single use

5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and CeporexÂ® On Formulary other beta‐lactams‐>5.1.2.1 Cephalosporins‐>CEFALEXIN 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase CERITINIB On Formulary inhibitors CernevitÂ® On Formulary 9.3 Intravenous nutrition‐>Supplementary preparations 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.1 Antihistamines‐>Non‐sedating antihistamines‐>CETIRIZINE Cetirizine On Formulary HYDROCHLORIDE

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ CETIRIZINE HYDROCHLORIDE On Formulary >3.4.1 Antihistamines‐>Non‐sedating antihistamines 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐ CetrabenÂ® On Formulary >Proprietary emollient preparations 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.3 CETRIMIDE On Formulary Cationic surfactants and soaps Only Tisept kept at the RFH. 4.10 Drugs used in substance dependence‐>4.10.2 Nicotine ChampixÂ® On Formulary dependence‐>Varenicline‐>VARENICLINE

CHARCOAL, ACTIVATED On Formulary Removal and elimination‐>Removal from the gastro‐intestinal tract Removal and elimination‐>Removal from the gastro‐intestinal tract‐ CharcodoteÂ® On Formulary >CHARCOAL, ACTIVATED

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ ChemydurÂ® 60XL On Formulary >2.6.1 Nitrates‐>ISOSORBIDE MONONITRATE‐>Modified release

ChirocaineÂ® On Formulary 15.2 Local anaesthesia‐>Levobupivacaine‐>LEVOBUPIVACAINE 4.1 Hypnotics and anxiolytics‐>4.1.1 Hypnotics‐>Chloral and CHLORAL HYDRATE On Formulary derivatives 4.1 Hypnotics and anxiolytics‐>4.1.1 Hypnotics‐>Chloral and Chloral Mixture, BP 2000 On Formulary derivatives‐>CHLORAL HYDRATE CHLORAMBUCIL On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs

CHLORAMPHENICOL On Formulary 11.3 Anti‐infective eye preparations‐>11.3.1 Antibacterials 11.3 Anti‐infective eye preparations‐>11.3.1 Antibacterials‐ Chloramphenicol On Formulary >CHLORAMPHENICOL 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.2 ChloraPrepÂ® On Formulary Chlorhexidine salts‐>CHLORHEXIDINE

12.3 Drugs acting on the oropharynx‐>12.3.4 Mouthwashes, gargles, Chlorhexidine On Formulary and dentifrices‐>CHLORHEXIDINE GLUCONATE MRSA screening procedure 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.2 CHLORHEXIDINE On Formulary Chlorhexidine salts 12.3 Drugs acting on the oropharynx‐>12.3.4 Mouthwashes, gargles, CHLORHEXIDINE GLUCONATE On Formulary and dentifrices MRSA screening procedure 11.3 Anti‐infective eye preparations‐>11.3.1 Antibacterials‐ ChloromycetinÂ® On Formulary >CHLORAMPHENICOL 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.1 Antihistamines‐>Sedating antihistamines‐>CHLORPHENAMINE Chlorphenamine On Formulary MALEATE

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ CHLORPHENAMINE MALEATE On Formulary >3.4.1 Antihistamines‐>Sedating antihistamines 4.6 Drugs used in nausea and vertigo‐>Phenothiazines and related The suppositories are not kept at the CHLORPROMAZINE HYDROCHLORIDE On Formulary drugs RFH.

12.3 Drugs acting on the oropharynx‐>12.3.1 Drugs for oral ulceration Choline Salicylate Dental Gel, BP On Formulary and inflammation‐>SALICYLATES‐>Choline salicylate

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ CHORIONIC GONADOTROPHIN On Formulary >Anterior pituitary hormones‐>Gonadotrophins Chronic hepatitis COn Formulary 5.3 Antiviral drugs‐>5.3.3 Viral hepatitis 8.2 Drugs affecting the immune response‐>8.2.2 Corticosteroids and CICLOSPORIN On Formulary other immunosuppressants 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Drugs affecting the immune CICLOSPORIN On Formulary response 13.5 Preparations for eczema and psoriasis‐>13.5.3 Drugs affecting CICLOSPORIN On Formulary the immune response

7.3 Contraceptives‐>7.3.1 Combined hormonal contraceptives‐ >COMBINED HORMONAL CONTRACEPTIVES‐>Oral (low and standard CilestÂ® On Formulary strength)‐>Ethinylestradiol with Norgestimate 1.3 Antisecretory drugs and mucosal protectants‐>1.3.1 H2‐receptor CIMETIDINE On Formulary antagonists CINNARIZINE On Formulary 4.6 Drugs used in nausea and vertigo‐>Antihistamines

Cinnarizine On Formulary 4.6 Drugs used in nausea and vertigo‐>Antihistamines‐>CINNARIZINE 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake CipramilÂ® On Formulary inhibitors‐>CITALOPRAM CIPROFIBRATE On Formulary 2.12 Lipid‐regulating drugs‐>Fibrates 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Platinum CISPLATIN On Formulary compounds 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Platinum Cisplatin On Formulary compounds‐>CISPLATIN 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake CITALOPRAM On Formulary inhibitors 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake Citalopram On Formulary inhibitors‐>CITALOPRAM

Citanest 1%Â® On Formulary 15.2 Local anaesthesia‐>Prilocaine‐>PRILOCAINE HYDROCHLORIDE 15.2 Local anaesthesia‐>Prilocaine‐>PRILOCAINE HYDROCHLORIDE‐ Citanest 3% with OctapressinÂ® On Formulary >For dental use CLADRIBINE On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites CLARITHROMYCIN On Formulary 5.1 Antibacterial drugs‐>5.1.5 Macrolides

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Clarithromycin On Formulary 5.1 Antibacterial drugs‐>5.1.5 Macrolides‐>CLARITHROMYCIN 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐infective CLIOQUINOL On Formulary preparations CLOBETASOL PROPIONATE On Formulary 13.4 Topical corticosteroids CLOBETASONE BUTYRATE On Formulary 13.4 Topical corticosteroids

CLOMETHIAZOLE On Formulary 4.1 Hypnotics and anxiolytics‐>4.1.1 Hypnotics‐>Clomethiazole

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ ClomidÂ® On Formulary >Anti‐oestrogens‐>CLOMIFENE CITRATE

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ Clomifene On Formulary >Anti‐oestrogens‐>CLOMIFENE CITRATE 6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ CLOMIFENE CITRATE On Formulary >Anti‐oestrogens

4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant Clomipramine On Formulary drugs‐>Tricyclic antidepressants‐>CLOMIPRAMINE HYDROCHLORIDE 4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant CLOMIPRAMINE HYDROCHLORIDE On Formulary drugs‐>Tricyclic antidepressants 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ CLONAZEPAM On Formulary >Benzodiazepines 4.7 Analgesics‐>4.7.4 Antimigraine drugs‐>4.7.4.2 Prophylaxis of Clonidine On Formulary migraine‐>CLONIDINE HYDROCHLORIDE 2.5 Hypertension and heart failure‐>2.5.2 Centrally acting Only 25 microgram tablets and the CLONIDINE HYDROCHLORIDE On Formulary antihypertensive drugs injection kept at the RFH 4.7 Analgesics‐>4.7.4 Antimigraine drugs‐>4.7.4.2 Prophylaxis of CLONIDINE HYDROCHLORIDE On Formulary migraine CLOPIDOGREL On Formulary 2.9 Antiplatelet drugs 7.2 Treatment of vaginal and vulval conditions‐>7.2.2 Vaginal and vulval infections‐>Fungal infections‐>PREPARATIONS FOR VAGINAL Clotrimazole On Formulary AND VULVAL CANDIDIASIS 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐infective CLOTRIMAZOLE On Formulary preparations 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal CLOTRIMAZOLE On Formulary preparations 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal Clotrimazole On Formulary preparations‐>CLOTRIMAZOLE

CO‐AMILOFRUSE On Formulary 2.2 Diuretics‐>2.2.4 Potassium‐sparing diuretics with other diuretics 2.2 Diuretics‐>2.2.4 Potassium‐sparing diuretics with other diuretics‐ Co‐amilofruse On Formulary >CO‐AMILOFRUSE 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.3 Broad‐spectrum CO‐AMOXICLAV On Formulary penicillins 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.3 Broad‐spectrum Co‐amoxiclav On Formulary penicillins‐>CO‐AMOXICLAV

4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 CO‐BENELDOPA On Formulary Dopaminergic drugs used in Parkinson's disease‐>Levodopa

4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 CO‐CARELDOPA On Formulary Dopaminergic drugs used in Parkinson's disease‐>Levodopa 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Levodopa‐>CO‐ Co‐careldopa On Formulary CARELDOPA 4.7 Analgesics‐>4.7.1 Non‐opioid analgesics and compound analgesic CO‐CODAMOL On Formulary preparations

4.7 Analgesics‐>4.7.1 Non‐opioid analgesics and compound analgesic Co‐codamol 8/500 On Formulary preparations‐>CO‐CODAMOL‐>With codeine phosphate 8Â mg 13.6 Acne and rosacea‐>13.6.2 Oral preparations for acne‐>Hormone CO‐CYPRINDIOL On Formulary treatment for acne 4.7 Analgesics‐>4.7.1 Non‐opioid analgesics and compound analgesic CO‐DYDRAMOL On Formulary preparations 1.1 Dyspepsia and gastro‐oesophageal reflux disease‐>1.1.1 Antacids and simeticone‐>Aluminium‐ and magnesium‐containing antacids‐ Co‐magaldrox On Formulary >ALUMINIUM HYDROXIDE Only Mucogel kept CO‐TENIDONE On Formulary 2.4 Beta‐adrenoceptor blocking drugs Co‐tenidone On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>CO‐TENIDONE

There are non‐proprietary 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for preparations available at the Royal psoriasis‐>Topical preparations for psoriasis‐>Tars‐>TARS‐>Non‐ Free Hospital but not listed in the Coal Tar and Salicylic Acid Ointment, BP On Formulary proprietary preparations eBNF, contact Pharmacy for details. 3.9 Cough preparations‐>3.9.1 Cough suppressants‐>CODEINE Codeine Linctus, BP On Formulary PHOSPHATE

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

CODEINE PHOSPHATE On Formulary 1.4 Acute diarrhoea‐>1.4.2 Antimotility drugs CODEINE PHOSPHATE On Formulary 3.9 Cough preparations‐>3.9.1 Cough suppressants CODEINE PHOSPHATE On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics

Codeine Phosphate On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>CODEINE PHOSPHATE

10.1 Drugs used in rheumatic diseases and gout‐>10.1.4 Gout and COLCHICINE On Formulary cytotoxic‐induced hyperuricaemia‐>Acute attacks of gout 10.1 Drugs used in rheumatic diseases and gout‐>10.1.4 Gout and cytotoxic‐induced hyperuricaemia‐>Acute attacks of gout‐ Colchicine On Formulary >COLCHICINE COLECALCIFEROL On Formulary 9.6 Vitamins‐>9.6.4 Vitamin D 2.12 Lipid‐regulating drugs‐>Bile acid sequestrants‐>COLESTIPOL ColestidÂ® On Formulary HYDROCHLORIDE COLESTIPOL HYDROCHLORIDE On Formulary 2.12 Lipid‐regulating drugs‐>Bile acid sequestrants

COLESTYRAMINE On Formulary 1.9 Drugs affecting intestinal secretions‐>1.9.2 Bile acid sequestrants COLESTYRAMINE On Formulary 2.12 Lipid‐regulating drugs‐>Bile acid sequestrants

Colestyramine On Formulary 2.12 Lipid‐regulating drugs‐>Bile acid sequestrants‐>COLESTYRAMINE 1.2 Antispasmodics and other drugs altering gut motility‐>Other ColofacÂ® On Formulary antispasmodics‐>MEBEVERINE HYDROCHLORIDE 1.2 Antispasmodics and other drugs altering gut motility‐>Other ColperminÂ® On Formulary antispasmodics‐>PEPPERMINT OIL

COMBINED HORMONAL CONTRACEPTIVES On Formulary 7.3 Contraceptives‐>7.3.1 Combined hormonal contraceptives

5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse CombivirÂ® On Formulary transcriptase inhibitors‐>ZIDOVUDINE‐>With lamivudine As per HIV guidelines. Compound haemorrhoidal preparations with Administration of enemas or corticosteroids On Formulary 1.7 Local preparations for anal and rectal disorders suppositories 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Catechol‐O‐ ComtessÂ® On Formulary methyltransferase inhibitors‐>ENTACAPONE 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.2 Plasma and plasma substitutes‐ Concentrated solutions (20%) On Formulary >ALBUMIN SOLUTION Available via the blood bank 2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ >Supraventricular and ventricular arrhythmias‐>AMIODARONE Cordarone XÂ® On Formulary HYDROCHLORIDE

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ CordiloxÂ® On Formulary >2.6.2 Calcium‐channel blockers‐>VERAPAMIL HYDROCHLORIDE 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.1 Nitrates‐>GLYCERYL TRINITRATE‐>Short‐acting tablets and Coro‐Nitro Pump SprayÂ® On Formulary sprays 12.3 Drugs acting on the oropharynx‐>12.3.1 Drugs for oral ulceration CORTICOSTEROIDS On Formulary and inflammation

9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency CosmoFerÂ® On Formulary anaemias‐>9.1.1.2 Parenteral iron‐>IRON DEXTRAN Renal anaemia

11.6 Treatment of glaucoma‐>Carbonic anhydrase inhibitors and CosoptÂ® On Formulary systemic drugs‐>DORZOLAMIDE‐>With timolol 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.2 Angiotensin‐II receptor antagonists‐ CozaarÂ® On Formulary >LOSARTAN POTASSIUM 1.9 Drugs affecting intestinal secretions‐>1.9.4 Pancreatin‐ CreonÂ® 10â€‰000 On Formulary >PANCREATIN 1.9 Drugs affecting intestinal secretions‐>1.9.4 Pancreatin‐ CreonÂ® 25Â 000 On Formulary >PANCREATIN‐>Higher‐strength preparations 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Asparaginase, CRISANTASPASE On Formulary crisantaspase and pegaspargase 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors‐ CrixivanÂ® On Formulary >INDINAVIR As per HIV guidelines. CROTAMITON On Formulary 13.3 Topical local anaesthetics and antipruritics

5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.1 Benzylpenicillin and CrystapenÂ® On Formulary phenoxymethylpenicillin‐>BENZYLPENICILLIN SODIUM CYCLIZINE On Formulary 4.6 Drugs used in nausea and vertigo‐>Antihistamines 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.2 Progestogens and progesterone receptor modulators‐ CyclogestÂ® On Formulary >PROGESTERONE CYCLOPENTOLATE HYDROCHLORIDE On Formulary 11.5 Mydriatics and cycloplegics‐>Antimuscarinics CYCLOPHOSPHAMIDE On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs

Cyclophosphamide On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs‐>CYCLOPHOSPHAMIDE

CyklokapronÂ® On Formulary 2.11 Antifibrinolytic drugs and haemostatics‐>TRANEXAMIC ACID

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

CyklokapronÂ® On Formulary 2.11 Antifibrinolytic drugs and haemostatics‐>TRANEXAMIC ACID

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ CYPROHEPTADINE HYDROCHLORIDE On Formulary >3.4.1 Antihistamines‐>Sedating antihistamines 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Anti‐ CyprostatÂ® On Formulary androgens‐>CYPROTERONE ACETATE 6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists‐>Anti‐ CYPROTERONE ACETATE On Formulary androgens‐>Cyproterone acetate

6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists‐>Anti‐ Cyproterone Acetate On Formulary androgens‐>Cyproterone acetate‐>CYPROTERONE ACETATE 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Anti‐ CYPROTERONE ACETATE On Formulary androgens 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Anti‐ Cyproterone Acetate On Formulary androgens‐>CYPROTERONE ACETATE 7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary frequency, enuresis, and incontinence‐>Urinary incontinence‐ CystrinÂ® On Formulary >OXYBUTYNIN HYDROCHLORIDE Only 5mg Tablets kept CYTARABINE On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites Cytarabine On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites‐>CYTARABINE 1.3 Antisecretory drugs and mucosal protectants‐>1.3.4 Prostaglandin CytotecÂ® On Formulary analogues‐>MISOPROSTOL North London Cancer Network Cytotoxic drugs On Formulary Cytotoxic Policy 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase DABRAFENIB On Formulary inhibitors 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Dacarbazine DACARBAZINE On Formulary and temozolomide 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Dacarbazine Dacarbazine On Formulary and temozolomide‐>DACARBAZINE Dacarbazine and temozolomide On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs

12.3 Drugs acting on the oropharynx‐>12.3.2 Oropharyngeal anti‐ DaktarinÂ® On Formulary infective drugs‐>Oropharyngeal fungal infections‐>MICONAZOLE 7.2 Treatment of vaginal and vulval conditions‐>7.2.2 Vaginal and vulval infections‐>Other infections‐>PREPARATIONS FOR OTHER DalacinÂ® On Formulary VAGINAL INFECTIONS DalivitÂ® On Formulary 9.6 Vitamins‐>9.6.7 Multivitamin preparations

DANAZOL On Formulary 6.7 Other endocrine drugs‐>6.7.2 Drugs affecting gonadotrophins 6.7 Other endocrine drugs‐>6.7.2 Drugs affecting gonadotrophins‐ Danazol On Formulary >DANAZOL 6.7 Other endocrine drugs‐>6.7.2 Drugs affecting gonadotrophins‐ DanolÂ® On Formulary >DANAZOL 15.1 General anaesthesia‐>15.1.8 Drugs for malignant hyperthermia‐ Dantrium IntravenousÂ® On Formulary >DANTROLENE SODIUM 10.2 Drugs used in neuromuscular disorders‐>10.2.2 Skeletal muscle DantriumÂ® On Formulary relaxants‐>DANTROLENE SODIUM 10.2 Drugs used in neuromuscular disorders‐>10.2.2 Skeletal muscle DANTROLENE SODIUM On Formulary relaxants

DANTROLENE SODIUM On Formulary 15.1 General anaesthesia‐>15.1.8 Drugs for malignant hyperthermia 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Pyrimethamine‐ DaraprimÂ® On Formulary >PYRIMETHAMINE 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic DAUNORUBICIN On Formulary antibiotics 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic Daunorubicin On Formulary antibiotics‐>DAUNORUBICIN 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic DaunoXomeÂ® On Formulary antibiotics‐>DAUNORUBICIN‐>Lipid formulation Deca‐DurabolinÂ® On Formulary 6.4 Sex hormones‐>6.4.3 Anabolic steroids‐>NANDROLONE

9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in DEFERIPRONE On Formulary hypoplastic, haemolytic, and renal anaemias‐>Iron overload DEMECLOCYCLINE HYDROCHLORIDE On Formulary 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Valproate‐ DepakoteÂ® On Formulary >SODIUM VALPROATE‐>Valproic acid 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy‐ Depo‐MedroneÂ® On Formulary >METHYLPREDNISOLONE‐>Intramuscular depot

10.1 Drugs used in rheumatic diseases and gout‐>10.1.2 Corticosteroids‐>10.1.2.2 Local corticosteroid injections‐>LOCAL Depo‐MedroneÂ® On Formulary CORTICOSTEROID INJECTIONS‐>Methylprednisolone acetate

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

7.3 Contraceptives‐>7.3.2 Progestogen‐only contraceptives‐>7.3.2.2 Parenteral progestogen‐only contraceptives‐>PARENTERAL Depo‐ProveraÂ® On Formulary PROGESTOGEN‐ONLY CONTRACEPTIVES‐>Injectable preparations

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ DeponitÂ® On Formulary >2.6.1 Nitrates‐>GLYCERYL TRINITRATE‐>Transdermal preparations 13.10 Anti‐infective skin preparations‐>13.10.4 Parasiticidal Derbac‐MÂ® On Formulary preparations‐>Malathion‐>MALATHION 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐>With DermolÂ® On Formulary antimicrobials DermovateÂ® On Formulary 13.4 Topical corticosteroids‐>CLOBETASOL PROPIONATE DESFERRIOXAMINE MESILATE On Formulary Specific drugs‐>Iron salts 15.1 General anaesthesia‐>15.1.2 Inhalational anaesthetics‐>Volatile DESFLURANE On Formulary liquid anaesthetics 6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.2 Posterior pituitary hormones and antagonists‐>Posterior pituitary DESMOPRESSIN On Formulary hormones

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.2 Posterior pituitary hormones and antagonists‐>Posterior pituitary Desmopressin acetate On Formulary hormones‐>DESMOPRESSIN

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.2 Posterior pituitary hormones and antagonists‐>Posterior pituitary DesmosprayÂ® On Formulary hormones‐>DESMOPRESSIN

1.9 Drugs affecting intestinal secretions‐>1.9.1 Drugs affecting biliary DestolitÂ® On Formulary composition and flow‐>URSODEOXYCHOLIC ACID 7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary frequency, enuresis, and incontinence‐>Urinary incontinence‐ DetrunormÂ® On Formulary >PROPIVERINE HYDROCHLORIDE 7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary frequency, enuresis, and incontinence‐>Urinary incontinence‐ DetrusitolÂ® On Formulary >TOLTERODINE TARTRATE DEXAMETHASONE On Formulary 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy

Dexamethasone On Formulary 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy‐>DEXAMETHASONE 11.4 Corticosteroids and other anti‐inflammatory preparations‐ DEXAMETHASONE On Formulary >11.4.1 Corticosteroids 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ DEXAMETHASONE On Formulary inflammatory preparations‐>Corticosteroids 8.1 Cytotoxic drugs‐>Treatment for cytotoxic‐induced side‐effects‐ DEXRAZOXANE On Formulary >Anthracycline side‐effects

The following are available at RFH (i) 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid Dextran 70 6% and Sodium chloride and electrolyte imbalance‐>9.2.2.2 Plasma and plasma substitutes‐ 0.9% 500ml bags and (ii) Dextran 70 DEXTRAN 70 On Formulary >Plasma substitutes 6% and Glucose 5% 500ml bags.

4.7 Analgesics‐>4.7.2 Opioid analgesics‐>DIHYDROCODEINE Only the 60mg modified‐release DHC ContinusÂ® On Formulary TARTRATE‐>Modified release dihydrocodeine tablet is kept. Diabetic hypoglycaemia On Formulary Hypoglycaemia protocol

6.1 Drugs used in diabetes‐>6.1.6 Diagnostic and monitoring devices Diabur‐Test 5000Â® On Formulary for diabetes mellitus‐>Urinalysis‐>Glucose 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.1 DiamicronÂ® On Formulary Sulfonylureas‐>GLICLAZIDE 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>DIAMORPHINE Diamorphine On Formulary HYDROCHLORIDE DIAMORPHINE HYDROCHLORIDE On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics 11.6 Treatment of glaucoma‐>Carbonic anhydrase inhibitors and DiamoxÂ® On Formulary systemic drugs‐>ACETAZOLAMIDE

11.6 Treatment of glaucoma‐>Carbonic anhydrase inhibitors and DiamoxÂ® SR On Formulary systemic drugs‐>ACETAZOLAMIDE‐>Modified release 13.6 Acne and rosacea‐>13.6.2 Oral preparations for acne‐>Hormone DianetteÂ® On Formulary treatment for acne‐>CO‐CYPRINDIOL

6.1 Drugs used in diabetes‐>6.1.6 Diagnostic and monitoring devices DiastixÂ® On Formulary for diabetes mellitus‐>Urinalysis‐>Glucose

DIAZEPAM On Formulary 4.1 Hypnotics and anxiolytics‐>4.1.2 Anxiolytics‐>Benzodiazepines 4.1 Hypnotics and anxiolytics‐>4.1.2 Anxiolytics‐>Benzodiazepines‐ Diazepam On Formulary >DIAZEPAM

DIAZEPAM On Formulary 4.8 Antiepileptic drugs‐>4.8.2 Drugs used in status epilepticus

4.8 Antiepileptic drugs‐>4.8.2 Drugs used in status epilepticus‐ Only diazepam injection (emulsion) Diazepam On Formulary >DIAZEPAM and rectal solution kept at the RFH.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

10.2 Drugs used in neuromuscular disorders‐>10.2.2 Skeletal muscle DIAZEPAM On Formulary relaxants 15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ DIAZEPAM On Formulary operative drugs‐>15.1.4.1 Benzodiazepines 6.1 Drugs used in diabetes‐>6.1.4 Treatment of hypoglycaemia‐ DIAZOXIDE On Formulary >Chronic hypoglycaemia 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ DICLOFENAC SODIUM On Formulary steroidal anti‐inflammatory drugs 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ steroidal anti‐inflammatory drugs‐>DICLOFENAC SODIUM‐>Modified Diclomax RetardÂ® On Formulary release DICOBALT EDETATE On Formulary Other poisons‐>Cyanides Dicobalt Edetate On Formulary Other poisons‐>Cyanides‐>DICOBALT EDETATE 1.2 Antispasmodics and other drugs altering gut motility‐ DICYCLOVERINE HYDROCHLORIDE On Formulary >Antimuscarinics 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse DIDANOSINE On Formulary transcriptase inhibitors As per HIV guidelines. 8.3 Sex hormones and hormone antagonists in malignant disease‐ DIETHYLSTILBESTROL On Formulary >8.3.1 Oestrogens 8.3 Sex hormones and hormone antagonists in malignant disease‐ Diethylstilbestrol On Formulary >8.3.1 Oestrogens‐>DIETHYLSTILBESTROL

12.3 Drugs acting on the oropharynx‐>12.3.1 Drugs for oral ulceration DifflamÂ® On Formulary and inflammation‐>BENZYDAMINE HYDROCHLORIDE DIFLUCORTOLONE VALERATE On Formulary 13.4 Topical corticosteroids DIGOXIN On Formulary 2.1 Positive inotropic drugs‐>2.1.1 Cardiac glycosides

Digoxin On Formulary 2.1 Positive inotropic drugs‐>2.1.1 Cardiac glycosides‐>DIGOXIN 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>DIHYDROCODEINE Dihydrocodeine On Formulary TARTRATE DIHYDROCODEINE TARTRATE On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.2 Calcium‐channel blockers‐>DILTIAZEM HYDROCHLORIDE‐ Diltiazem On Formulary >Standard formulations 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ DILTIAZEM HYDROCHLORIDE On Formulary >2.6.2 Calcium‐channel blockers

Royal Free Maternity Unit Guideline DINOPROSTONE On Formulary 7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics for Induction of Labour

DioctylÂ® On Formulary 1.6 Laxatives‐>1.6.2 Stimulant laxatives‐>DOCUSATE SODIUM 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and electrolyte imbalance‐>9.2.1.2 Oral sodium and water‐>Oral rehydration therapy (ORT)‐>ORAL REHYDRATION SALTS (ORS)‐>UK DioralyteÂ® On Formulary formulations 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and electrolyte imbalance‐>9.2.1.2 Oral sodium and water‐>Oral rehydration therapy (ORT)‐>ORAL REHYDRATION SALTS (ORS)‐>UK DioralyteÂ® Relief On Formulary formulations 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.2 Angiotensin‐II receptor antagonists‐ DiovanÂ® On Formulary >VALSARTAN 1.5 Chronic bowel disorders‐>1.5.1 Aminosalicylates‐>OLSALAZINE DipentumÂ® On Formulary SODIUM Diphtheria, Tetanus, Pertussis (Acellular, Component), Poliomyelitis (Inactivated) and 14.4 Vaccines and antisera‐>Diphtheria vaccines‐>DIPHTHERIA‐ Haemophilus Type b Conjugate Vaccine CONTAINING VACCINES‐>Diphtheria‐containing vaccines for children (Adsorbed) On Formulary under 10 years

15.1 General anaesthesia‐>15.1.1 Intravenous anaesthetics‐>Drugs DiprivanÂ® On Formulary used for intravenous anaesthesia‐>PROPOFOL 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐ Only Cream available at the Royal DiprobaseÂ® On Formulary >Proprietary emollient preparations Free Hospital. 13.4 Topical corticosteroids‐>BETAMETHASONE ESTERS‐>With DiprosalicÂ® On Formulary salicylic acid Only Ointment available at the Royal DiprosoneÂ® On Formulary 13.4 Topical corticosteroids‐>BETAMETHASONE ESTERS Free Hospital. DIPYRIDAMOLE On Formulary 2.9 Antiplatelet drugs Dipyridamole On Formulary 2.9 Antiplatelet drugs‐>DIPYRIDAMOLE 2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ DISOPYRAMIDE On Formulary >Supraventricular and ventricular arrhythmias

2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ Disopyramide On Formulary >Supraventricular and ventricular arrhythmias‐>DISOPYRAMIDE 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Penicillamine‐ DistamineÂ® On Formulary >PENICILLAMINE 4.10 Drugs used in substance dependence‐>4.10.1 Alcohol DISULFIRAM On Formulary dependence‐>Disulfiram

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for DITHRANOL On Formulary psoriasis‐>Topical preparations for psoriasis‐>Dithranol

There are non‐proprietary 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for preparations available at the Royal psoriasis‐>Topical preparations for psoriasis‐>Dithranol‐>DITHRANOL‐ Free Hospital but not listed in the Dithranol Paste, BP On Formulary >Non‐proprietary preparations eBNF, contact Pharmacy for details.

13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Dithranol‐>DITHRANOL‐ DithrocreamÂ® On Formulary >Proprietary preparations 7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary frequency, enuresis, and incontinence‐>Urinary incontinence‐ DitropanÂ® On Formulary >OXYBUTYNIN HYDROCHLORIDE 2.5 Hypertension and heart failure‐>2.5.2 Centrally acting DixaritÂ® On Formulary antihypertensive drugs‐>CLONIDINE HYDROCHLORIDE 4.7 Analgesics‐>4.7.4 Antimigraine drugs‐>4.7.4.2 Prophylaxis of DixaritÂ® On Formulary migraine‐>CLONIDINE HYDROCHLORIDE

DOBUTAMINE On Formulary 2.7 Sympathomimetics‐>2.7.1 Inotropic sympathomimetics 2.7 Sympathomimetics‐>2.7.1 Inotropic sympathomimetics‐ Dobutamine On Formulary >DOBUTAMINE DOCUSATE SODIUM On Formulary 1.6 Laxatives‐>1.6.2 Stimulant laxatives

DocusolÂ® On Formulary 1.6 Laxatives‐>1.6.2 Stimulant laxatives‐>DOCUSATE SODIUM 4.6 Drugs used in nausea and vertigo‐>Domperidone and DOMPERIDONE On Formulary metoclopramide 4.6 Drugs used in nausea and vertigo‐>Domperidone and Domperidone On Formulary metoclopramide‐>DOMPERIDONE DONEPEZIL HYDROCHLORIDE On Formulary 4.11 Dementia 2.7 Sympathomimetics‐>2.7.1 Inotropic sympathomimetics‐ Dopamine On Formulary >DOPAMINE HYDROCHLORIDE

DOPAMINE HYDROCHLORIDE On Formulary 2.7 Sympathomimetics‐>2.7.1 Inotropic sympathomimetics 11.6 Treatment of glaucoma‐>Carbonic anhydrase inhibitors and DORZOLAMIDE On Formulary systemic drugs

4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant Dosulepin On Formulary drugs‐>Tricyclic antidepressants‐>DOSULEPIN HYDROCHLORIDE 4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant DOSULEPIN HYDROCHLORIDE On Formulary drugs‐>Tricyclic antidepressants 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐ DoublebaseÂ® On Formulary >Proprietary emollient preparations 3.5 Respiratory stimulants and pulmonary surfactants‐>3.5.1 DOXAPRAM HYDROCHLORIDE On Formulary Respiratory stimulants 2.5 Hypertension and heart failure‐>2.5.4 Alpha‐adrenoceptor DOXAZOSIN On Formulary blocking drugs 2.5 Hypertension and heart failure‐>2.5.4 Alpha‐adrenoceptor Doxazosin On Formulary blocking drugs‐>DOXAZOSIN 7.4 Drugs for genito‐urinary disorders‐>7.4.1 Drugs for urinary DOXAZOSIN On Formulary retention‐>Alpha‐blockers 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic Doxorubicin On Formulary antibiotics‐>DOXORUBICIN HYDROCHLORIDE 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic DOXORUBICIN HYDROCHLORIDE On Formulary antibiotics DOXYCYCLINE On Formulary 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines Doxycycline On Formulary 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines‐>DOXYCYCLINE

DOXYCYCLINE On Formulary 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Tetracyclines 12.3 Drugs acting on the oropharynx‐>12.3.1 Drugs for oral ulceration DOXYCYCLINE On Formulary and inflammation See Chapter 5.1.3 DriclorÂ® On Formulary 13.12 Hyperhidrosis‐>ALUMINIUM SALTS Available from the haemophilia DRIED PROTHROMBIN COMPLEX On Formulary 2.11 Antifibrinolytic drugs and haemostatics‐>Blood‐related products centre. Drugs that enhance neuromuscular transmission On Formulary 10.2 Drugs used in neuromuscular disorders Motor neuron disease policy North London Cancer Network Haematopoietic Colony‐Stimulating Drugs used in neutropenia On Formulary 9.1 Anaemias and some other blood disorders Factor Guidelines

Durogesic DTransÂ® On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>FENTANYL‐>Patches 2.2 Diuretics‐>2.2.4 Potassium‐sparing diuretics with other diuretics‐ DyazideÂ® On Formulary >Triamterene with thiazides

6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ DYDROGESTERONE On Formulary >6.4.1.2 Progestogens and progesterone receptor modulators 4.3 Antidepressant drugs‐>4.3.4 Other antidepressant drugs‐ EdronaxÂ® On Formulary >REBOXETINE

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Non‐nucleoside reverse EFAVIRENZ On Formulary transcriptase inhibitors As per HIV guidelines. 4.3 Antidepressant drugs‐>4.3.4 Other antidepressant drugs‐ EfexorÂ® XL On Formulary >VENLAFAXINE‐>Modified release 13.8 Sunscreens and camouflagers‐>13.8.1 Sunscreen preparations‐ EfudixÂ® On Formulary >Photodamage‐>FLUOROURACIL

4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Monoamine‐ EldeprylÂ® On Formulary oxidase‐B inhibitors‐>SELEGILINE HYDROCHLORIDE 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and electrolyte imbalance‐>9.2.1.2 Oral sodium and water‐>Oral rehydration therapy (ORT)‐>ORAL REHYDRATION SALTS (ORS)‐>UK ElectroladeÂ® On Formulary formulations

A2.1 Enteral feeds (non‐disease specific)‐>A2.1.1 Enteral feeds (non‐ disease specific): less than 5Â g protein/100Â mL‐>A2.1.1.2 Enteral feeds: Less than 1Â kcal/mL and less than 5Â g protein/100Â mL‐ Elemental 028Â® Extra On Formulary >Amino acid formula (essential and non‐essential amino acids) 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.1 Oestrogens and HRT‐>OESTROGENS FOR HRT‐>Estradiol with Elleste‐DuetÂ® On Formulary progestogen

6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ Elleste‐SoloÂ® On Formulary >6.4.1.1 Oestrogens and HRT‐>OESTROGENS FOR HRT‐>Estradiol only EloconÂ® On Formulary 13.4 Topical corticosteroids‐>MOMETASONE FUROATE 15.2 Local anaesthesia‐>Lidocaine‐>LIDOCAINE HYDROCHLORIDE‐ EMLAÂ® On Formulary >With prilocaine 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse EMTRICITABINE On Formulary transcriptase inhibitors As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse EmtrivaÂ® On Formulary transcriptase inhibitors‐>EMTRICITABINE As per HIV guidelines. 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐>Non‐ Emulsifying Ointment, BP On Formulary proprietary emollient preparations 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme ENALAPRIL MALEATE On Formulary inhibitors 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme Enalapril Maleate On Formulary inhibitors‐>ENALAPRIL MALEATE 14.4 Vaccines and antisera‐>Hepatitis B vaccine‐>HEPATITIS B Engerix BÂ® On Formulary VACCINE‐>Single component 2.1 Positive inotropic drugs‐>2.1.2 Phosphodiesterase type‐3 ENOXIMONE On Formulary inhibitors

A2.4 Feed supplements‐>A2.4.1 High‐energy supplements‐>A2.4.1.3 EnshakeÂ® On Formulary High‐energy supplements: protein‐>Protein, fat, and carbohydrate A2.2 Nutritional supplements (non‐disease specific)‐>A2.2.1 Nutritional supplements: less than 5Â g protein/100Â mL‐>A2.2.1.2 Nutritional supplements: More than 1Â kcal/mL and less than 5Â g EnsureÂ® Plus Juce On Formulary protein/100Â mL 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Catechol‐O‐ ENTACAPONE On Formulary methyltransferase inhibitors

EntocortÂ® On Formulary 1.5 Chronic bowel disorders‐>1.5.2 Corticosteroids‐>BUDESONIDE 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Anti‐ ENZALUTAMIDE On Formulary androgens 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐ EpadermÂ® On Formulary >Proprietary emollient preparations

4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Phenytoin‐ 300mg capsules and the 50mg EpanutinÂ® On Formulary >PHENYTOIN Infatabs are not kept at the RFH.

12.2 Drugs acting on the nose‐>12.2.2 Topical nasal decongestants‐ Ephedrine On Formulary >Sympathomimetics‐>EPHEDRINE HYDROCHLORIDE

EPHEDRINE HYDROCHLORIDE On Formulary 2.7 Sympathomimetics‐>2.7.2 Vasoconstrictor sympathomimetics 2.7 Sympathomimetics‐>2.7.2 Vasoconstrictor sympathomimetics‐ Ephedrine Hydrochloride On Formulary >EPHEDRINE HYDROCHLORIDE 3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.2 Other EPHEDRINE HYDROCHLORIDE On Formulary adrenoceptor agonists

3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.2 Other Ephedrine Hydrochloride On Formulary adrenoceptor agonists‐>EPHEDRINE HYDROCHLORIDE 12.2 Drugs acting on the nose‐>12.2.2 Topical nasal decongestants‐ EPHEDRINE HYDROCHLORIDE On Formulary >Sympathomimetics 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Valproate‐ Epilim ChronoÂ® On Formulary >SODIUM VALPROATE‐>Modified release

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Valproate‐ EpilimÂ® On Formulary >SODIUM VALPROATE‐>Oral 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Valproate‐ EpilimÂ® Intravenous On Formulary >SODIUM VALPROATE‐>Parenteral 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.3 Allergic emergencies‐>Anaphylaxis‐ >ADRENALINE/EPINEPHRINE‐>Intramuscular injection for self‐ EpiPenÂ® On Formulary administration 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic EPIRUBICIN HYDROCHLORIDE On Formulary antibiotics 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse EpivirÂ® On Formulary transcriptase inhibitors‐>LAMIVUDINE As per HIV guidelines.

9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in EPOETIN ALFA, BETA, and ZETA On Formulary hypoplastic, haemolytic, and renal anaemias‐>Erythropoietins 9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in hypoplastic, haemolytic, and renal anaemias‐>Erythropoietins‐ Epoetin beta On Formulary >EPOETIN ALFA, BETA, and ZETA RENAL ANAEMIA ERGOCALCIFEROL On Formulary 9.6 Vitamins‐>9.6.4 Vitamin D 7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics‐ Ergometrine On Formulary >ERGOMETRINE MALEATE

ERGOMETRINE MALEATE On Formulary 7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics

8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Asparaginase, ErwinaseÂ® On Formulary crisantaspase and pegaspargase‐>CRISANTASPASE ERYTHROMYCIN On Formulary 5.1 Antibacterial drugs‐>5.1.5 Macrolides Erythromycin On Formulary 5.1 Antibacterial drugs‐>5.1.5 Macrolides‐>ERYTHROMYCIN Erythromycin Ethyl Succinate On Formulary 5.1 Antibacterial drugs‐>5.1.5 Macrolides‐>ERYTHROMYCIN 15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ >Non‐depolarising neuromuscular blocking drugs‐>ROCURONIUM EsmeronÂ® On Formulary BROMIDE 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs‐>ETHAMBUTOL Ethambutol On Formulary HYDROCHLORIDE ETHAMBUTOL HYDROCHLORIDE On Formulary 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs

6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ ETHINYLESTRADIOL On Formulary >6.4.1.1 Oestrogens and HRT‐>Ethinylestradiol

6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ Ethinylestradiol On Formulary >6.4.1.1 Oestrogens and HRT‐>Ethinylestradiol‐>ETHINYLESTRADIOL 7.3 Contraceptives‐>7.3.1 Combined hormonal contraceptives‐ >COMBINED HORMONAL CONTRACEPTIVES‐>Oral (low and standard Ethinylestradiol with Levonorgestrel On Formulary strength) Only Microgynon 30 kept at the RFH

ETHOSUXIMIDE On Formulary 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Ethosuximide 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Ethosuximide‐ Ethosuximide On Formulary >ETHOSUXIMIDE 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ ETODOLAC On Formulary steroidal anti‐inflammatory drugs 15.1 General anaesthesia‐>15.1.1 Intravenous anaesthetics‐>Drugs ETOMIDATE On Formulary used for intravenous anaesthesia

10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Etopan XLÂ® On Formulary steroidal anti‐inflammatory drugs‐>ETODOLAC‐>Modified release ETOPOSIDE On Formulary 8.1 Cytotoxic drugs‐>8.1.4 Vinca alkaloids and etoposide

Etoposide On Formulary 8.1 Cytotoxic drugs‐>8.1.4 Vinca alkaloids and etoposide‐>ETOPOSIDE 6.1 Drugs used in diabetes‐>6.1.4 Treatment of hypoglycaemia‐ EudemineÂ® On Formulary >Chronic hypoglycaemia‐>DIAZOXIDE EumovateÂ® On Formulary 13.4 Topical corticosteroids‐>CLOBETASONE BUTYRATE

EuraxÂ® On Formulary 13.3 Topical local anaesthetics and antipruritics‐>CROTAMITON 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.1 Oestrogens and HRT‐>Raloxifene‐>RALOXIFENE EvistaÂ® On Formulary HYDROCHLORIDE

6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ EvorelÂ® On Formulary >6.4.1.1 Oestrogens and HRT‐>OESTROGENS FOR HRT‐>Estradiol only

ExelonÂ® On Formulary 4.11 Dementia‐>RIVASTIGMINE 4.5mg and 6mg capsules are not kept.

8.3 Sex hormones and hormone antagonists in malignant disease‐ EXEMESTANE On Formulary >8.3.4 Hormone antagonists‐>8.3.4.1 Breast cancer 10.3 Drugs for the treatment of soft‐tissue disorders and topical pain Extravasation On Formulary relief Extravasation Guideline 9.8 Metabolic disorders‐>9.8.1 Drugs used in metabolic disorders‐ FabrazymeÂ® On Formulary >Fabry's disease‐>AGALSIDASE ALFA and BETA 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake FaverinÂ® On Formulary inhibitors‐>FLUVOXAMINE MALEATE

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ FeldeneÂ® On Formulary steroidal anti‐inflammatory drugs‐>PIROXICAM Only 10mg capsules kept at the RFH

8.3 Sex hormones and hormone antagonists in malignant disease‐ FemaraÂ® On Formulary >8.3.4 Hormone antagonists‐>8.3.4.1 Breast cancer‐>LETROZOLE

7.3 Contraceptives‐>7.3.1 Combined hormonal contraceptives‐ >COMBINED HORMONAL CONTRACEPTIVES‐>Oral (low and standard FemodeneÂ® On Formulary strength)‐>Ethinylestradiol with Gestodene 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.1 Oestrogens and HRT‐>OESTROGENS FOR HRT‐>Estradiol with FemostonÂ® On Formulary progestogen FENOFIBRATE On Formulary 2.12 Lipid‐regulating drugs‐>Fibrates Fenofibrate On Formulary 2.12 Lipid‐regulating drugs‐>Fibrates‐>FENOFIBRATE FENTANYL On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics

Fentanyl On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>FENTANYL‐>Patches 15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ FENTANYL On Formulary operative drugs‐>15.1.4.3 Opioid analgesics Controlled Drug Requirements

15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ Fentanyl On Formulary operative drugs‐>15.1.4.3 Opioid analgesics‐>FENTANYL Controlled Drug Requirements 9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency FERRIC CARBOXYMALTOSE On Formulary anaemias‐>9.1.1.2 Parenteral iron 9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in hypoplastic, haemolytic, and renal anaemias‐>Iron overload‐ FerriproxÂ® On Formulary >DEFERIPRONE 9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency FERROUS GLUCONATE On Formulary anaemias‐>9.1.1.1 Oral iron

9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency Ferrous Gluconate On Formulary anaemias‐>9.1.1.1 Oral iron‐>FERROUS GLUCONATE 9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency FERROUS SULFATE On Formulary anaemias‐>9.1.1.1 Oral iron 9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency Ferrous Sulfate On Formulary anaemias‐>9.1.1.1 Oral iron‐>FERROUS SULFATE

6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists‐>Anti‐ FINASTERIDE On Formulary androgens‐>Dutasteride and finasteride 5.1 Antibacterial drugs‐>5.1.11 Metronidazole and tinidazole‐ FlagylÂ® On Formulary >METRONIDAZOLE 13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial preparations‐>13.10.1.1 Antibacterial preparations only used FlamazineÂ® On Formulary topically‐>SILVER SULFADIAZINE

7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary FLAVOXATE HYDROCHLORIDE On Formulary frequency, enuresis, and incontinence‐>Urinary incontinence

2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ Flecainide On Formulary >Supraventricular and ventricular arrhythmias‐>FLECAINIDE ACETATE 2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ FLECAINIDE ACETATE On Formulary >Supraventricular and ventricular arrhythmias 1.6 Laxatives‐>1.6.5 Bowel cleansing preparations‐>PHOSPHATES Fleet Phospho‐sodaÂ® On Formulary (ORAL)

FleetÂ® Ready‐to‐use Enema On Formulary 1.6 Laxatives‐>1.6.4 Osmotic laxatives‐>PHOSPHATES (RECTAL) 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ Flixonase NasuleÂ® On Formulary >Corticosteroids‐>FLUTICASONE PROPIONATE 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ FlixonaseÂ® On Formulary >Corticosteroids‐>FLUTICASONE PROPIONATE

7.4 Drugs for genito‐urinary disorders‐>7.4.1 Drugs for urinary FlomaxtraÂ® XL On Formulary retention‐>Alpha‐blockers‐>TAMSULOSIN HYDROCHLORIDE 6.3 Corticosteroids‐>6.3.1 Replacement therapy‐>FLUDROCORTISONE FlorinefÂ® On Formulary ACETATE 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.2 Penicillinase‐ FLUCLOXACILLIN On Formulary resistant penicillins 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.2 Penicillinase‐ Flucloxacillin On Formulary resistant penicillins‐>FLUCLOXACILLIN 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites‐>FLUDARABINE FludaraÂ® On Formulary PHOSPHATE FLUDARABINE PHOSPHATE On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites FLUDROCORTISONE ACETATE On Formulary 6.3 Corticosteroids‐>6.3.1 Replacement therapy 15.1 General anaesthesia‐>15.1.7 Antagonists for central and NPSA guidance on conscious sedation FLUMAZENIL On Formulary respiratory depression policy. 15.1 General anaesthesia‐>15.1.7 Antagonists for central and NPSA guidance on conscious sedation Flumazenil On Formulary respiratory depression‐>FLUMAZENIL policy. 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ FLUMETASONE PIVALATE On Formulary inflammatory preparations‐>Corticosteroids FLUOCINOLONE ACETONIDE On Formulary 13.4 Topical corticosteroids

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

FLUOCINONIDE On Formulary 13.4 Topical corticosteroids 11.8 Miscellaneous ophthalmic preparations‐>11.8.2 Ocular diagnostic and peri‐operative preparations and photodynamic FLUORESCEIN SODIUM On Formulary treatment‐>Ocular diagnostic preparations 11.4 Corticosteroids and other anti‐inflammatory preparations‐ FLUOROMETHOLONE On Formulary >11.4.1 Corticosteroids FLUOROURACIL On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites

Fluorouracil On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites‐>FLUOROURACIL 13.8 Sunscreens and camouflagers‐>13.8.1 Sunscreen preparations‐ FLUOROURACIL On Formulary >Photodamage 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake FLUOXETINE On Formulary inhibitors 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake Fluoxetine On Formulary inhibitors‐>FLUOXETINE 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ FLURBIPROFEN On Formulary steroidal anti‐inflammatory drugs 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Flurbiprofen On Formulary steroidal anti‐inflammatory drugs‐>FLURBIPROFEN 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Anti‐ FLUTAMIDE On Formulary androgens 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Anti‐ Flutamide On Formulary androgens‐>FLUTAMIDE FLUTICASONE On Formulary 3.2 Corticosteroids 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ FLUTICASONE PROPIONATE On Formulary >Corticosteroids 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake Fluvoxamine On Formulary inhibitors‐>FLUVOXAMINE MALEATE 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake FLUVOXAMINE MALEATE On Formulary inhibitors

11.4 Corticosteroids and other anti‐inflammatory preparations‐ FMLÂ® On Formulary >11.4.1 Corticosteroids‐>FLUOROMETHOLONE 9.1 Anaemias and some other blood disorders‐>9.1.2 Drugs used in FOLIC ACID On Formulary megaloblastic anaemias 9.1 Anaemias and some other blood disorders‐>9.1.2 Drugs used in Folic Acid On Formulary megaloblastic anaemias‐>FOLIC ACID

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ FOLLITROPIN ALFA and BETA On Formulary >Anterior pituitary hormones‐>Gonadotrophins IVIG patient registration form must be completed when initiating IVIG therapy before product can be dispensed. Consult your ward pharmacist for which brand to 14.5 Immunoglobulins‐>14.5.1 Normal immunoglobulin‐>NORMAL prescribe. IVIG patient registration For intravenous use On Formulary IMMUNOGLOBULIN form

3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective Formoterol On Formulary beta2 agonists‐>FORMOTEROL FUMARATE 3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective FORMOTEROL FUMARATE On Formulary beta2 agonists 6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and other drugs affecting bone metabolism‐>Bisphosphonates‐ FosamaxÂ® On Formulary >ALENDRONIC ACID 6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and other drugs affecting bone metabolism‐>Bisphosphonates‐ FosamaxÂ® Once Weekly On Formulary >ALENDRONIC ACID

FOSAMPRENAVIR On Formulary 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors As per HIV guidelines. 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐>Fosfomycin‐ Fosfomycin On Formulary >FOSFOMYCIN 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐infective FRAMYCETIN SULFATE On Formulary preparations 13.4 Topical corticosteroids‐>BETAMETHASONE ESTERS‐>With Only the Cream available at the Royal FucibetÂ® On Formulary antimicrobials Free Hospital.

Fucidin HÂ® On Formulary 13.4 Topical corticosteroids‐>HYDROCORTISONE‐>With antimicrobials 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐>Fusidic acid‐ FucidinÂ® On Formulary >SODIUM FUSIDATE 11.3 Anti‐infective eye preparations‐>11.3.1 Antibacterials‐>FUSIDIC FucithalmicÂ® On Formulary ACID FUROSEMIDE On Formulary 2.2 Diuretics‐>2.2.2 Loop diuretics Furosemide On Formulary 2.2 Diuretics‐>2.2.2 Loop diuretics‐>FUROSEMIDE

FUSIDIC ACID On Formulary 11.3 Anti‐infective eye preparations‐>11.3.1 Antibacterials

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial preparations‐>13.10.1.2 Antibacterial preparations also used FUSIDIC ACID On Formulary systemically

FybogelÂ® On Formulary 1.6 Laxatives‐>1.6.1 Bulk‐forming laxatives‐>ISPAGHULA HUSK 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Gabapentin GABAPENTIN On Formulary and pregabalin 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Gabapentin Gabapentin On Formulary and pregabalin‐>GABAPENTIN 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Tiagabine‐ GabitrilÂ® On Formulary >TIAGABINE Only 5mg tablets kept. 3.10 Systemic nasal decongestants‐>PSEUDOEPHEDRINE GalpseudÂ® On Formulary HYDROCHLORIDE IVIG patient registration form must be completed when initiating IVIG therapy before product can be dispensed. Consult your ward pharmacist for which brand to 14.5 Immunoglobulins‐>14.5.1 Normal immunoglobulin‐>NORMAL prescribe. IVIG patient registration Gammagard S/DÂ® On Formulary IMMUNOGLOBULIN‐>For intravenous use form IVIG patient registration form must be completed when initiating IVIG therapy before product can be dispensed. Consult your ward 14.5 Immunoglobulins‐>14.5.1 Normal immunoglobulin‐>NORMAL pharmacist for which brand to GammaplexÂ® On Formulary IMMUNOGLOBULIN‐>For intravenous use prescribe. 1.1 Dyspepsia and gastro‐oesophageal reflux disease‐>1.1.2 Compound alginates and proprietary indigestion preparations‐>Other GastrocoteÂ® On Formulary compound alginate preparations 1.1 Dyspepsia and gastro‐oesophageal reflux disease‐>1.1.2 Compound alginates and proprietary indigestion preparations‐>Other Gaviscon InfantÂ® On Formulary compound alginate preparations 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.2 Plasma and plasma substitutes‐ GELATIN On Formulary >Plasma substitutes 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.2 Plasma and plasma substitutes‐ GelofusineÂ® On Formulary >Plasma substitutes‐>GELATIN GEMCITABINE On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites

GEMEPROST On Formulary 7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics 7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics‐ Gemeprost On Formulary >GEMEPROST GEMFIBROZIL On Formulary 2.12 Lipid‐regulating drugs‐>Fibrates Gemfibrozil On Formulary 2.12 Lipid‐regulating drugs‐>Fibrates‐>GEMFIBROZIL GemzarÂ® On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites‐>GEMCITABINE RFL adult aminoglycoside dosing GENTAMICIN On Formulary 5.1 Antibacterial drugs‐>5.1.4 Aminoglycosides guideline RFL adult aminoglycoside dosing Gentamicin On Formulary 5.1 Antibacterial drugs‐>5.1.4 Aminoglycosides‐>GENTAMICIN guideline

GENTAMICIN On Formulary 11.3 Anti‐infective eye preparations‐>11.3.1 Antibacterials 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐infective GENTAMICIN On Formulary preparations 11.3 Anti‐infective eye preparations‐>11.3.1 Antibacterials‐ GenticinÂ® On Formulary >GENTAMICIN 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐infective GenticinÂ® On Formulary preparations‐>GENTAMICIN 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ inflammatory preparations‐>Corticosteroids‐>HYDROCORTISONE‐ GentisoneÂ® HC On Formulary >With antibacterial 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐infective GentisoneÂ® HC On Formulary preparations‐>GENTAMICIN‐>With corticosteroid 12.3 Drugs acting on the oropharynx‐>12.3.5 Treatment of dry mouth‐ GlandosaneÂ® On Formulary >Local treatment 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.1 GLIBENCLAMIDE On Formulary Sulfonylureas 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.1 Glibenclamide On Formulary Sulfonylureas‐>GLIBENCLAMIDE 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.1 GLICLAZIDE On Formulary Sulfonylureas 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.1 Gliclazide On Formulary Sulfonylureas‐>GLICLAZIDE 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.1 GLIPIZIDE On Formulary Sulfonylureas 6.1 Drugs used in diabetes‐>6.1.4 Treatment of hypoglycaemia‐ GlucaGenÂ® HypoKit On Formulary >GLUCAGON

GLUCAGON On Formulary 6.1 Drugs used in diabetes‐>6.1.4 Treatment of hypoglycaemia

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other GlucobayÂ® On Formulary antidiabetic drugs‐>ACARBOSE 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ GLUCOSE On Formulary >Intravenous glucose 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ Glucose Intravenous Infusion On Formulary >Intravenous glucose‐>GLUCOSE GLUTARALDEHYDE On Formulary 13.7 Preparations for warts and calluses

GlutarolÂ® On Formulary 13.7 Preparations for warts and calluses‐>GLUTARALDEHYDE GLYCEROL On Formulary 1.6 Laxatives‐>1.6.2 Stimulant laxatives Administration of enemas or Glycerol Suppositories, BP On Formulary 1.6 Laxatives‐>1.6.2 Stimulant laxatives‐>GLYCEROL suppositories 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ GLYCERYL TRINITRATE On Formulary >2.6.1 Nitrates 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.1 Nitrates‐>GLYCERYL TRINITRATE‐>Short‐acting tablets and Only 500 microgram tablets and 400 Glyceryl Trinitrate On Formulary sprays microgram spray kept at the RFH.

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Glyceryl Trinitrate On Formulary >2.6.1 Nitrates‐>GLYCERYL TRINITRATE‐>Parenteral preparations 7.4 Drugs for genito‐urinary disorders‐>7.4.4 Bladder instillations and GLYCINE On Formulary urological surgery‐>Urological surgery

7.4 Drugs for genito‐urinary disorders‐>7.4.4 Bladder instillations and Glycine Irrigation Solution On Formulary urological surgery‐>Urological surgery‐>GLYCINE GLYCOPYRRONIUM BROMIDE On Formulary 15.1 General anaesthesia‐>15.1.3 Antimuscarinic drugs

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.2 Posterior pituitary hormones and antagonists‐>Posterior pituitary GlypressinÂ® On Formulary hormones‐>TERLIPRESSIN ACETATE 6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ GONADORELIN On Formulary >Hypothalamic hormones

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ Gonadorelin On Formulary >Hypothalamic hormones‐>GONADORELIN 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Gonadorelin GOSERELIN On Formulary analogues 9.1 Anaemias and some other blood disorders‐>9.1.6 Drugs used in GranocyteÂ® On Formulary neutropenia‐>LENOGRASTIM 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ GRASS AND TREE POLLEN EXTRACTS On Formulary >3.4.2 Allergen immunotherapy GRISEOFULVIN On Formulary 5.2 Antifungal drugs‐>5.2.5 Other antifungals

Griseofulvin On Formulary 5.2 Antifungal drugs‐>5.2.5 Other antifungals‐>GRISEOFULVIN 2.5 Hypertension and heart failure‐>2.5.3 Adrenergic neurone GUANETHIDINE MONOSULFATE On Formulary blocking drugs 7.2 Treatment of vaginal and vulval conditions‐>7.2.2 Vaginal and Only "Gyno‐Pevaryl 1" vulval infections‐>Fungal infections‐>PREPARATIONS FOR VAGINAL single dose Pessary kept at Royal Free Gyno‐PevarylÂ® On Formulary AND VULVAL CANDIDIASIS Hospital HAEM ARGINATE On Formulary 9.8 Metabolic disorders‐>9.8.2 Acute porphyrias 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.2 Calcium‐channel blockers‐>VERAPAMIL HYDROCHLORIDE‐ Half Securon SRÂ® On Formulary >Modified release 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Levodopa‐>CO‐ Half SinemetÂ® CR On Formulary CARELDOPA‐>Modified release 14.4 Vaccines and antisera‐>Hepatitis A vaccine‐>HEPATITIS A Havrix MonodoseÂ® On Formulary VACCINE‐>Single component 14.4 Vaccines and antisera‐>Hepatitis B vaccine‐>HEPATITIS B HBvaxPROÂ® On Formulary VACCINE‐>Single component 7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics‐ HemabateÂ® On Formulary >CARBOPROST Unfractionated heparin IV Heparin On Formulary 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants administration protocol 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ Unfractionated heparin IV HEPARIN On Formulary >Heparin administration protocol 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ Heparin Sodium On Formulary >Heparin flushes 14.5 Immunoglobulins‐>14.5.2 Disease‐specific immunoglobulins‐ HEPATITIS B IMMUNOGLOBULIN On Formulary >Hepatitis B 14.5 Immunoglobulins‐>14.5.2 Disease‐specific immunoglobulins‐ >Hepatitis B‐>HEPATITIS B IMMUNOGLOBULIN‐>For intramuscular Hepatitis B Immunoglobulin On Formulary use 14.4 Vaccines and antisera‐>Hepatitis A vaccine‐>HEPATITIS A HepatyrixÂ® On Formulary VACCINE‐>With typhoid vaccine

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.2 HibiscrubÂ® On Formulary Chlorhexidine salts‐>CHLORHEXIDINE 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.2 Hibitane ObstetricÂ® On Formulary Chlorhexidine salts‐>CHLORHEXIDINE HirudoidÂ® On Formulary 13.13 Topical circulatory preparations 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.1 Short‐acting HumalogÂ® On Formulary insulins‐>INSULIN LISPRO

6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.2 Intermediate‐ and HumalogÂ® Mix50 On Formulary long‐acting insulins‐>Biphasic insulins‐>BIPHASIC INSULIN LISPRO

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ HUMAN MENOPAUSAL GONADOTROPHINS On Formulary >Anterior pituitary hormones‐>Gonadotrophins 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.1 Short‐acting Humulin SÂ® On Formulary insulins‐>INSULIN‐>Human sequence

10.3 Drugs for the treatment of soft‐tissue disorders and topical pain HyalaseÂ® On Formulary relief‐>10.3.1 Enzymes‐>Hyaluronidase‐>HYALURONIDASE 10.3 Drugs for the treatment of soft‐tissue disorders and topical pain HYALURONIDASE On Formulary relief‐>10.3.1 Enzymes‐>Hyaluronidase 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator Hydralazine On Formulary antihypertensive drugs‐>HYDRALAZINE HYDROCHLORIDE 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator HYDRALAZINE HYDROCHLORIDE On Formulary antihypertensive drugs 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐ HydreaÂ® On Formulary >Hydroxycarbamide‐>HYDROXYCARBAMIDE 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.2 HydrexÂ® On Formulary Chlorhexidine salts‐>CHLORHEXIDINE HYDROCORTISONE On Formulary 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy‐ Hydrocortisone On Formulary >HYDROCORTISONE 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ HYDROCORTISONE On Formulary inflammatory preparations‐>Corticosteroids 12.3 Drugs acting on the oropharynx‐>12.3.1 Drugs for oral ulceration Hydrocortisone On Formulary and inflammation‐>CORTICOSTEROIDS HYDROCORTISONE On Formulary 13.4 Topical corticosteroids Hydrocortisone On Formulary 13.4 Topical corticosteroids‐>HYDROCORTISONE HYDROCORTISONE BUTYRATE On Formulary 13.4 Topical corticosteroids

10.1 Drugs used in rheumatic diseases and gout‐>10.1.2 Corticosteroids‐>10.1.2.2 Local corticosteroid injections‐>LOCAL HydrocortistabÂ® On Formulary CORTICOSTEROID INJECTIONS‐>Hydrocortisone acetate 12.3 Drugs acting on the oropharynx‐>12.3.4 Mouthwashes, gargles, HYDROGEN PEROXIDE On Formulary and dentifrices 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.6 HYDROGEN PEROXIDE On Formulary Oxidisers and dyes

12.3 Drugs acting on the oropharynx‐>12.3.4 Mouthwashes, gargles, Hydrogen Peroxide Mouthwash, BP On Formulary and dentifrices‐>HYDROGEN PEROXIDE 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.6 Hydrogen Peroxide Solution, BP On Formulary Oxidisers and dyes‐>HYDROGEN PEROXIDE 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐ HydromolÂ® On Formulary >Proprietary emollient preparations

13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐>13.2.1.1 HydromolÂ® On Formulary Emollient bath and shower preparations 9.1 Anaemias and some other blood disorders‐>9.1.2 Drugs used in HYDROXOCOBALAMIN On Formulary megaloblastic anaemias

9.1 Anaemias and some other blood disorders‐>9.1.2 Drugs used in Hydroxocobalamin On Formulary megaloblastic anaemias‐>HYDROXOCOBALAMIN Hydroxycarbamide On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐ HYDROXYCARBAMIDE On Formulary >Hydroxycarbamide 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐ Hydroxycarbamide On Formulary >Hydroxycarbamide‐>HYDROXYCARBAMIDE

10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that HYDROXYCHLOROQUINE SULFATE On Formulary suppress the rheumatic disease process‐>Antimalarials 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.2 Plasma and plasma substitutes‐ HYDROXYETHYL STARCH On Formulary >Plasma substitutes

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ HYDROXYZINE HYDROCHLORIDE On Formulary >3.4.1 Antihistamines‐>Sedating antihistamines 15.1 General anaesthesia‐>15.1.3 Antimuscarinic drugs‐>HYOSCINE Hyoscine On Formulary HYDROBROMIDE 1.2 Antispasmodics and other drugs altering gut motility‐ HYOSCINE BUTYLBROMIDE On Formulary >Antimuscarinics

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

HYOSCINE HYDROBROMIDE On Formulary 4.6 Drugs used in nausea and vertigo‐>Hyoscine HYOSCINE HYDROBROMIDE On Formulary 15.1 General anaesthesia‐>15.1.3 Antimuscarinic drugs

RescueFlow bags are not kept at RFH. The following are available at RFH (i) 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid Dextran 70 6% and Sodium chloride and electrolyte imbalance‐>9.2.2.2 Plasma and plasma substitutes‐ 0.9% 500ml bags and (ii) Dextran 70 Hypertonic solution On Formulary >Plasma substitutes‐>DEXTRAN 70 6% and Glucose 5% 500ml bags.

15.1 General anaesthesia‐>15.1.1 Intravenous anaesthetics‐>Drugs HypnomidateÂ® On Formulary used for intravenous anaesthesia‐>ETOMIDATE

15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ HypnovelÂ® On Formulary operative drugs‐>15.1.4.1 Benzodiazepines‐>MIDAZOLAM Status Epilepticus

Hypoglycaemia On Formulary Prescribing in dental practice‐>Medical emergencies in dental practice Hypoglycaemia protocol 2.5 Hypertension and heart failure‐>2.5.4 Alpha‐adrenoceptor HypovaseÂ® On Formulary blocking drugs‐>PRAZOSIN 11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, HYPROMELLOSE On Formulary ocular lubricants, and astringents

11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, Hypromellose On Formulary ocular lubricants, and astringents‐>HYPROMELLOSE 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ IBUPROFEN On Formulary steroidal anti‐inflammatory drugs 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Ibuprofen On Formulary steroidal anti‐inflammatory drugs‐>IBUPROFEN 13.5 Preparations for eczema and psoriasis‐>13.5.1 Preparations for Only Ichthamol Bandage available at ICHTHAMMOL On Formulary eczema‐>Topical preparations for eczema the RFH. 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic IDARUBICIN HYDROCHLORIDE On Formulary antibiotics 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase IDELALISIB On Formulary inhibitors

North London Cancer Network Guidelines for Use of Methylene Blue IFOSFAMIDE On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs for Ifosfamide‐Induced Encephalitis

North London Cancer Network Guidelines for Use of Methylene Blue Ifosfamide On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs‐>IFOSFAMIDE for Ifosfamide‐Induced Encephalitis

11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, IlubeÂ® On Formulary ocular lubricants, and astringents‐>ACETYLCYSTEINE

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ ImdurÂ® On Formulary >2.6.1 Nitrates‐>ISOSORBIDE MONONITRATE‐>Modified release

4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant Imipramine On Formulary drugs‐>Tricyclic antidepressants‐>IMIPRAMINE HYDROCHLORIDE 4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant IMIPRAMINE HYDROCHLORIDE On Formulary drugs‐>Tricyclic antidepressants

IMIQUIMOD On Formulary 13.7 Preparations for warts and calluses‐>Anogenital warts 1.4 Acute diarrhoea‐>1.4.2 Antimotility drugs‐>LOPERAMIDE ImodiumÂ® On Formulary HYDROCHLORIDE 8.2 Drugs affecting the immune response‐>8.2.1 Antiproliferative ImuranÂ® On Formulary immunosuppressants‐>AZATHIOPRINE INDAPAMIDE On Formulary 2.2 Diuretics‐>2.2.1 Thiazides and related diuretics

Indapamide On Formulary 2.2 Diuretics‐>2.2.1 Thiazides and related diuretics‐>INDAPAMIDE

INDINAVIR On Formulary 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors As per HIV guidelines. 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ INDOMETACIN On Formulary steroidal anti‐inflammatory drugs 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Indometacin On Formulary steroidal anti‐inflammatory drugs‐>INDOMETACIN 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.1 Industrial Methylated Spirit, BP On Formulary Alcohols and saline‐>ALCOHOL

Click on section 5.6 for RFH Trust antimicrobial prescribing guidelines . Infections On Formulary Antibiotic prescribing aid 3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective Administration of drugs via inhalers Inhalation On Formulary beta2 agonists‐>SALBUTAMOL guideline

Injections of vitamins B and COn Formulary 9.6 Vitamins‐>9.6.2 Vitamin B group‐>PYRIDOXINE HYDROCHLORIDE See under thiamine (Pabrinex) Injections of vitamins B and COn Formulary 9.6 Vitamins‐>9.6.2 Vitamin B group‐>NICOTINAMIDE See under thiamine (Pabrinex)

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ Low molecular weight heparin InnohepÂ® On Formulary >Low molecular weight heparins‐>TINZAPARIN SODIUM protocol 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme InnovaceÂ® On Formulary inhibitors‐>ENALAPRIL MALEATE 15.2 Local anaesthesia‐>Lidocaine‐>LIDOCAINE HYDROCHLORIDE‐ InstillagelÂ® On Formulary >Lidocaine for surface anaesthesia

6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.2 Intermediate‐ and InsulatardÂ® On Formulary long‐acting insulins‐>ISOPHANE INSULIN‐>Human sequence 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.1 Short‐acting INSULIN On Formulary insulins Insulin Sliding Scale 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.1 Short‐acting INSULIN ASPART On Formulary insulins 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.2 Intermediate‐ and INSULIN GLARGINE On Formulary long‐acting insulins 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.1 Short‐acting INSULIN LISPRO On Formulary insulins

3.3 Cromoglicate and related therapy, leukotriene receptor antagonists, and phosphodiesterase type‐4 inhibitors‐>3.3.1 IntalÂ® CFC‐Free Inhaler On Formulary Cromoglicate and related therapy‐>SODIUM CROMOGLICATE Only available at the RNTNE. 8.2 Drugs affecting the immune response‐>8.2.4 Other INTERFERON ALFA On Formulary immunomodulating drugs‐>Interferon alfa 8.2 Drugs affecting the immune response‐>8.2.4 Other INTERFERON BETA On Formulary immunomodulating drugs‐>Interferon beta

7.3 Contraceptives‐>7.3.2 Progestogen‐only contraceptives‐>7.3.2.3 INTRA‐UTERINE PROGESTOGEN‐ONLY SYSTEM On Formulary Intra‐uterine progestogen‐only device IVIG patient registration form must be completed when initiating IVIG therapy before product can be dispensed. Consult your ward pharmacist for which brand to 14.5 Immunoglobulins‐>14.5.1 Normal immunoglobulin‐>NORMAL prescribe. IVIG patient registration IntratectÂ® On Formulary IMMUNOGLOBULIN‐>For intravenous use form

Only the Nutriflex, Vamin and Intralipid ranges are formulary at RFH Intravenous nutrition On Formulary Parenteral Nutrition Guidelines

9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid Intravenous potassium On Formulary and electrolyte imbalance‐>9.2.2.1 Electrolytes and water IV Potassium Administration Policy

8.2 Drugs affecting the immune response‐>8.2.4 Other IntronAÂ® On Formulary immunomodulating drugs‐>Interferon alfa‐>INTERFERON ALFA 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors‐ InviraseÂ® On Formulary >SAQUINAVIR As per HIV guidelines. IODINE AND IODIDE On Formulary 6.2 Thyroid and antithyroid drugs‐>6.2.2 Antithyroid drugs NICE approved, notification only as Ipilimumab On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs per NICE TAs below

IPRATROPIUM BROMIDE On Formulary 3.1 Bronchodilators‐>3.1.2 Antimuscarinic bronchodilators 3.1 Bronchodilators‐>3.1.2 Antimuscarinic bronchodilators‐ Ipratropium Bromide On Formulary >IPRATROPIUM BROMIDE 12.2 Drugs acting on the nose‐>12.2.2 Topical nasal decongestants‐ IPRATROPIUM BROMIDE On Formulary >Antimuscarinic 3.1 Bronchodilators‐>3.1.2 Antimuscarinic bronchodilators‐ Ipratropium Steri‐NebÂ® On Formulary >IPRATROPIUM BROMIDE 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐ IRINOTECAN HYDROCHLORIDE On Formulary >Topoisomerase I inhibitors 9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency IRON DEXTRAN On Formulary anaemias‐>9.1.1.2 Parenteral iron 9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency IRON SUCROSE On Formulary anaemias‐>9.1.1.2 Parenteral iron

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Isib 60XLÂ® On Formulary >2.6.1 Nitrates‐>ISOSORBIDE MONONITRATE‐>Modified release

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Ismo RetardÂ® On Formulary >2.6.1 Nitrates‐>ISOSORBIDE MONONITRATE‐>Modified release

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ IsmoÂ® On Formulary >2.6.1 Nitrates‐>ISOSORBIDE MONONITRATE

ISOCARBOXAZID On Formulary 4.3 Antidepressant drugs‐>4.3.2 Monoamine‐oxidase inhibitors 4.3 Antidepressant drugs‐>4.3.2 Monoamine‐oxidase inhibitors‐ Isocarboxazid On Formulary >ISOCARBOXAZID

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

15.1 General anaesthesia‐>15.1.2 Inhalational anaesthetics‐>Volatile ISOFLURANE On Formulary liquid anaesthetics 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.1 Nitrates‐>ISOSORBIDE DINITRATE‐>Modified‐release Isoket RetardÂ® On Formulary preparations ISONIAZID On Formulary 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs

Isoniazid On Formulary 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs‐>ISONIAZID 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.2 Intermediate‐ and ISOPHANE INSULIN On Formulary long‐acting insulins 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ ISOSORBIDE DINITRATE On Formulary >2.6.1 Nitrates 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.1 Nitrates‐>ISOSORBIDE DINITRATE‐>Short‐acting tablets and Isosorbide Dinitrate On Formulary sprays 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ ISOSORBIDE MONONITRATE On Formulary >2.6.1 Nitrates

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ 40mg tablets not stocked in Isosorbide Mononitrate On Formulary >2.6.1 Nitrates‐>ISOSORBIDE MONONITRATE pharmacy 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.2 Plasma and plasma substitutes‐ Isotonic solutions On Formulary >ALBUMIN SOLUTION Available via the blood bank 13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐>Topical ISOTRETINOIN On Formulary retinoids and related preparations for acne 13.6 Acne and rosacea‐>13.6.2 Oral preparations for acne‐>Oral ISOTRETINOIN On Formulary retinoid for acne 13.6 Acne and rosacea‐>13.6.2 Oral preparations for acne‐>Oral Isotretinoin On Formulary retinoid for acne‐>ISOTRETINOIN

13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐>Topical IsotrexÂ® On Formulary retinoids and related preparations for acne‐>ISOTRETINOIN 13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐>Topical retinoids and related preparations for acne‐>ISOTRETINOIN‐>With IsotrexinÂ® On Formulary antibacterial ISPAGHULA HUSK On Formulary 1.6 Laxatives‐>1.6.1 Bulk‐forming laxatives

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ IstinÂ® On Formulary >2.6.2 Calcium‐channel blockers‐>AMLODIPINE

A2.1 Enteral feeds (non‐disease specific)‐>A2.1.1 Enteral feeds (non‐ disease specific): less than 5Â g protein/100Â mL‐>A2.1.1.1 Enteral JevityÂ® On Formulary feeds: 1Â kcal/mL and less than 5Â g protein/100Â mL

A2.1 Enteral feeds (non‐disease specific)‐>A2.1.2 Enteral feeds (non‐ disease specific): 5Â g (or more) protein/100Â mL‐>A2.1.2.1 Enteral JevityÂ® 1.5â€‰kcal On Formulary feeds: 1.5Â kcal/mL and 5Â g (or more) protein/100Â mL 4.6 Drugs used in nausea and vertigo‐>Hyoscine‐>HYOSCINE Joy RidesÂ® On Formulary HYDROBROMIDE 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors‐ KaletraÂ® On Formulary >LOPINAVIR WITH RITONAVIR As per HIV guidelines. 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and electrolyte imbalance‐>9.2.1.1 Oral potassium‐>POTASSIUM Kay‐Cee‐LÂ® On Formulary CHLORIDE

5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and KeflexÂ® On Formulary other beta‐lactams‐>5.1.2.1 Cephalosporins‐>CEFALEXIN 4.9 Drugs used in parkinsonism and related disorders‐>4.9.2 Antimuscarinic drugs used in parkinsonism‐>PROCYCLIDINE KemadrinÂ® On Formulary HYDROCHLORIDE 4.9 Drugs used in parkinsonism and related disorders‐>4.9.2 Antimuscarinic drugs used in parkinsonism‐>PROCYCLIDINE KemadrinÂ® On Formulary HYDROCHLORIDE

KenalogÂ® Intra‐articular/Intramuscular On Formulary 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy‐>TRIAMCINOLONE

10.1 Drugs used in rheumatic diseases and gout‐>10.1.2 Corticosteroids‐>10.1.2.2 Local corticosteroid injections‐>LOCAL KenalogÂ® Intra‐articular/Intramuscular On Formulary CORTICOSTEROID INJECTIONS‐>Triamcinolone acetonide 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ 750mg tablets are not kept at the KeppraÂ® On Formulary >Levetiracetam and brivaracetam‐>LEVETIRACETAM RFH.

15.1 General anaesthesia‐>15.1.1 Intravenous anaesthetics‐>Drugs Controlled Drugs Storage and KetalarÂ® On Formulary used for intravenous anaesthesia‐>KETAMINE Ordering Requirements 15.1 General anaesthesia‐>15.1.1 Intravenous anaesthetics‐>Drugs Controlled Drugs Storage and KETAMINE On Formulary used for intravenous anaesthesia Ordering Requirements

6.1 Drugs used in diabetes‐>6.1.6 Diagnostic and monitoring devices KetostixÂ® On Formulary for diabetes mellitus‐>Urinalysis‐>Ketones

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

9.6 Vitamins‐>9.6.7 Multivitamin preparations‐>Vitamin and mineral KetoviteÂ® On Formulary supplements and adjuncts to synthetic diets IVIG patient registration form must be completed when initiating IVIG therapy before product can be dispensed. Consult your ward pharmacist for which brand to 14.5 Immunoglobulins‐>14.5.1 Normal immunoglobulin‐>NORMAL prescribe. IVIG patient registration KiovigÂ® On Formulary IMMUNOGLOBULIN‐>For intravenous use form

5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse KivexaÂ® On Formulary transcriptase inhibitors‐>ABACAVIR‐>With lamivudine As per HIV guidelines.

KlaricidÂ® On Formulary 5.1 Antibacterial drugs‐>5.1.5 Macrolides‐>CLARITHROMYCIN

Klean‐PrepÂ® On Formulary 1.6 Laxatives‐>1.6.5 Bowel cleansing preparations‐>MACROGOLS 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.1 Oestrogens and HRT‐>OESTROGENS FOR HRT‐>Estradiol with KliofemÂ® On Formulary progestogen 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.1 Oestrogens and HRT‐>OESTROGENS FOR HRT‐>Estradiol with KliovanceÂ® On Formulary progestogen 9.6 Vitamins‐>9.6.6 Vitamin K‐>PHYTOMENADIONE‐>Colloidal KonakionÂ® MM On Formulary formulation 9.6 Vitamins‐>9.6.6 Vitamin K‐>PHYTOMENADIONE‐>Colloidal Administration of Vitamin K to the KonakionÂ® MM Paediatric On Formulary formulation Newborn LABETALOL HYDROCHLORIDE On Formulary 2.4 Beta‐adrenoceptor blocking drugs

Labetalol Hydrochloride On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>LABETALOL HYDROCHLORIDE LACTULOSE On Formulary 1.6 Laxatives‐>1.6.4 Osmotic laxatives Lactulose On Formulary 1.6 Laxatives‐>1.6.4 Osmotic laxatives‐>LACTULOSE 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Lamotrigine‐ 2mg and 5mg chewable tablets are LamictalÂ® On Formulary >LAMOTRIGINE not kept at the RFH.

LamisilÂ® On Formulary 5.2 Antifungal drugs‐>5.2.5 Other antifungals‐>TERBINAFINE 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse LAMIVUDINE On Formulary transcriptase inhibitors As per HIV guidelines.

LAMOTRIGINE On Formulary 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Lamotrigine 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Lamotrigine‐ Lamotrigine On Formulary >LAMOTRIGINE

Lanoxin‐PGÂ® On Formulary 2.1 Positive inotropic drugs‐>2.1.1 Cardiac glycosides‐>DIGOXIN

LanoxinÂ® On Formulary 2.1 Positive inotropic drugs‐>2.1.1 Cardiac glycosides‐>DIGOXIN 1.3 Antisecretory drugs and mucosal protectants‐>1.3.5 Proton pump LANSOPRAZOLE On Formulary inhibitors 1.3 Antisecretory drugs and mucosal protectants‐>1.3.5 Proton pump Lansoprazole On Formulary inhibitors‐>LANSOPRAZOLE LanvisÂ® On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites‐>TIOGUANINE 15.2 Local anaesthesia‐>Lidocaine‐>LIDOCAINE HYDROCHLORIDE‐ LaryngojetÂ® On Formulary >Lidocaine for surface anaesthesia Available at the RNTNE only. LasixÂ® On Formulary 2.2 Diuretics‐>2.2.2 Loop diuretics‐>FUROSEMIDE 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Drugs affecting the immune LEFLUNOMIDE On Formulary response REGISTERED THALIDOMIDE 8.2 Drugs affecting the immune response‐>8.2.4 Other PRESCRIBERS CAN PRESCRIBE Lenalidomide, pomalidomide, and thalidomide On Formulary immunomodulating drugs THALIDOMIDE 9.1 Anaemias and some other blood disorders‐>9.1.6 Drugs used in LENOGRASTIM On Formulary neutropenia

8.3 Sex hormones and hormone antagonists in malignant disease‐ LETROZOLE On Formulary >8.3.4 Hormone antagonists‐>8.3.4.1 Breast cancer

LeukeranÂ® On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs‐>CHLORAMBUCIL 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ LEVETIRACETAM On Formulary >Levetiracetam and brivaracetam 11.6 Treatment of glaucoma‐>Beta‐blockers‐>LEVOBUNOLOL Levobunolol On Formulary HYDROCHLORIDE LEVOBUNOLOL HYDROCHLORIDE On Formulary 11.6 Treatment of glaucoma‐>Beta‐blockers LEVOBUPIVACAINE On Formulary 15.2 Local anaesthesia‐>Levobupivacaine 9.8 Metabolic disorders‐>9.8.1 Drugs used in metabolic disorders‐ LEVOCARNITINE On Formulary >Carnitine deficiency 7.3 Contraceptives‐>7.3.5 Emergency contraception‐>Hormonal LevonelleÂ® 1500 On Formulary methods‐>LEVONORGESTREL 7.3 Contraceptives‐>7.3.5 Emergency contraception‐>Hormonal LEVONORGESTREL On Formulary methods 6.2 Thyroid and antithyroid drugs‐>6.2.1 Thyroid hormones‐ Levothyroxine On Formulary >LEVOTHYROXINE SODIUM

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

LEVOTHYROXINE SODIUM On Formulary 6.2 Thyroid and antithyroid drugs‐>6.2.1 Thyroid hormones 2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐>Ventricular Lidocaine On Formulary arrhythmias‐>LIDOCAINE HYDROCHLORIDE 12.3 Drugs acting on the oropharynx‐>12.3.1 Drugs for oral ulceration Lidocaine On Formulary and inflammation‐>LOCAL ANAESTHETICS 15.2 Local anaesthesia‐>Lidocaine‐>LIDOCAINE HYDROCHLORIDE‐ Lidocaine On Formulary >Lidocaine hydrochloride injections

Lidocaine for ear, nose, and oropharyngeal use On Formulary 15.2 Local anaesthesia‐>Lidocaine‐>LIDOCAINE HYDROCHLORIDE Available at the RNTNE only. 2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐>Ventricular LIDOCAINE HYDROCHLORIDE On Formulary arrhythmias LIDOCAINE HYDROCHLORIDE On Formulary 15.2 Local anaesthesia‐>Lidocaine

15.2 Local anaesthesia‐>Lidocaine‐>LIDOCAINE HYDROCHLORIDE‐ Lidocaine with phenylephrine On Formulary >Lidocaine for ear, nose, and oropharyngeal use Available at the RNTNE only. 10.2 Drugs used in neuromuscular disorders‐>10.2.2 Skeletal muscle LioresalÂ® On Formulary relaxants‐>BACLOFEN LipantilÂ® On Formulary 2.12 Lipid‐regulating drugs‐>Fibrates‐>FENOFIBRATE

LipostatÂ® On Formulary 2.12 Lipid‐regulating drugs‐>Statins‐>PRAVASTATIN SODIUM 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐>Non‐ Liquid and White Soft Paraffin Ointment, NPF On Formulary proprietary emollient preparations Liquid Paraffin and Magnesium Hydroxide Oral 1.6 Laxatives‐>1.6.4 Osmotic laxatives‐>MAGNESIUM SALTS‐ Emulsion, BP On Formulary >Magnesium hydroxide with liquid paraffin

11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, polyvinyl alcohol 1.4% with povidone Liquifilm TearsÂ® On Formulary ocular lubricants, and astringents‐>POLYVINYL ALCOHOL 0.6% is not kept at RFH. A2.4 Feed supplements‐>A2.4.1 High‐energy supplements‐>A2.4.1.2 LiquigenÂ® On Formulary High‐energy supplements: fat 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme LISINOPRIL On Formulary inhibitors 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme Lisinopril On Formulary inhibitors‐>LISINOPRIL LitakÂ® On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites‐>CLADRIBINE 4.2 Drugs used in psychoses and related disorders‐>4.2.3 Drugs used LITHIUM CITRATE On Formulary for mania and hypomania‐>Lithium 12.3 Drugs acting on the oropharynx‐>12.3.1 Drugs for oral ulceration LOCAL ANAESTHETICS On Formulary and inflammation 10.1 Drugs used in rheumatic diseases and gout‐>10.1.2 LOCAL CORTICOSTEROID INJECTIONS On Formulary Corticosteroids‐>10.1.2.2 Local corticosteroid injections LocoidÂ® On Formulary 13.4 Topical corticosteroids‐>HYDROCORTISONE BUTYRATE 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ inflammatory preparations‐>Corticosteroids‐>FLUMETASONE Locorten‐VioformÂ® On Formulary PIVALATE‐>With antibacterial 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐infective Locorten‐VioformÂ® On Formulary preparations‐>CLIOQUINOL‐>With corticosteroid

10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Lodine SRÂ® On Formulary steroidal anti‐inflammatory drugs‐>ETODOLAC‐>Modified release

11.4 Corticosteroids and other anti‐inflammatory preparations‐ LODOXAMIDE On Formulary >11.4.2 Other anti‐inflammatory preparations

7.3 Contraceptives‐>7.3.1 Combined hormonal contraceptives‐ >COMBINED HORMONAL CONTRACEPTIVES‐>Oral (low and standard Loestrin 20Â® On Formulary strength)‐>Ethinylestradiol with Norethisterone

7.3 Contraceptives‐>7.3.1 Combined hormonal contraceptives‐ >COMBINED HORMONAL CONTRACEPTIVES‐>Oral (low and standard Loestrin 30Â® On Formulary strength)‐>Ethinylestradiol with Norethisterone 4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant LOFEPRAMINE On Formulary drugs‐>Tricyclic antidepressants

4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant Lofepramine On Formulary drugs‐>Tricyclic antidepressants‐>LOFEPRAMINE LOMUSTINE On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs Lomustine On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs‐>LOMUSTINE 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator LonitenÂ® On Formulary antihypertensive drugs‐>MINOXIDIL 1.4 Acute diarrhoea‐>1.4.2 Antimotility drugs‐>LOPERAMIDE Loperamide On Formulary HYDROCHLORIDE LOPERAMIDE HYDROCHLORIDE On Formulary 1.4 Acute diarrhoea‐>1.4.2 Antimotility drugs LopidÂ® On Formulary 2.12 Lipid‐regulating drugs‐>Fibrates‐>GEMFIBROZIL

LOPINAVIR WITH RITONAVIR On Formulary 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors As per HIV guidelines. Metoprolol injection restricted to LopresorÂ® On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>METOPROLOL TARTRATE cardiology and ITU only.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ LORATADINE On Formulary >3.4.1 Antihistamines‐>Non‐sedating antihistamines

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ Loratadine On Formulary >3.4.1 Antihistamines‐>Non‐sedating antihistamines‐>LORATADINE

LORAZEPAM On Formulary 4.1 Hypnotics and anxiolytics‐>4.1.2 Anxiolytics‐>Benzodiazepines 4.1 Hypnotics and anxiolytics‐>4.1.2 Anxiolytics‐>Benzodiazepines‐ Lorazepam On Formulary >LORAZEPAM

LORAZEPAM On Formulary 4.8 Antiepileptic drugs‐>4.8.2 Drugs used in status epilepticus 15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ LORAZEPAM On Formulary operative drugs‐>15.1.4.1 Benzodiazepines Status Epilepticus 6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and other drugs affecting bone metabolism‐>Bisphosphonates‐>SODIUM Loron 520Â® On Formulary CLODRONATE

2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ LOSARTAN POTASSIUM On Formulary angiotensin system‐>2.5.5.2 Angiotensin‐II receptor antagonists

Omeprazole injection and infusion are non‐formulary. Omeprazole infusions are prescribed only after recommendation by consultant gastroenterologist. Omeprazole is also available locally as a 10mg/5ml or 20mg/5ml suspension.Omeprazole tablets are restricted to 1.3 Antisecretory drugs and mucosal protectants‐>1.3.5 Proton pump paediatricians and for patients LosecÂ® On Formulary inhibitors‐>OMEPRAZOLE requiring a soluble tablet 11.6 Treatment of glaucoma‐>Prostaglandin analogues and LumiganÂ® On Formulary prostamides‐>BIMATOPROST 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake LustralÂ® On Formulary inhibitors‐>SERTRALINE 13.10 Anti‐infective skin preparations‐>13.10.4 Parasiticidal LyclearÂ® Creme Rinse On Formulary preparations‐>Permethrin‐>PERMETHRIN 13.10 Anti‐infective skin preparations‐>13.10.4 Parasiticidal LyclearÂ® Dermal Cream On Formulary preparations‐>Permethrin‐>PERMETHRIN LYMECYCLINE On Formulary 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Mitotane‐ LysodrenÂ® On Formulary >MITOTANE MACROGOLS On Formulary 1.6 Laxatives‐>1.6.4 Osmotic laxatives 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Levodopa‐>CO‐ 62.5mg dispersible tablets are not MadoparÂ® On Formulary BENELDOPA kept at the RFH. 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Levodopa‐>CO‐ MadoparÂ® CR On Formulary BENELDOPA‐>Modified release

1.1 Dyspepsia and gastro‐oesophageal reflux disease‐>1.1.1 Antacids MAGNESIUM CARBONATE On Formulary and simeticone‐>Aluminium‐ and magnesium‐containing antacids MAGNESIUM SALTS On Formulary 1.6 Laxatives‐>1.6.4 Osmotic laxatives

MAGNESIUM SULFATE On Formulary 9.5 Minerals‐>9.5.1 Calcium and magnesium‐>9.5.1.3 Magnesium 9.5 Minerals‐>9.5.1 Calcium and magnesium‐>9.5.1.3 Magnesium‐ Only magnesium sulphate 50% Magnesium Sulfate Injection, BP On Formulary >MAGNESIUM SULFATE injection kept at the RFH

13.10 Anti‐infective skin preparations‐>13.10.5 Preparations for Magnesium Sulfate Paste, BP On Formulary minor cuts and abrasions‐>Preparations for boils

1.1 Dyspepsia and gastro‐oesophageal reflux disease‐>1.1.1 Antacids MAGNESIUM TRISILICATE On Formulary and simeticone‐>Aluminium‐ and magnesium‐containing antacids 1.1 Dyspepsia and gastro‐oesophageal reflux disease‐>1.1.1 Antacids and simeticone‐>Aluminium‐ and magnesium‐containing antacids‐ Magnesium Trisilicate Mixture, BP On Formulary >MAGNESIUM TRISILICATE 13.10 Anti‐infective skin preparations‐>13.10.4 Parasiticidal MALATHION On Formulary preparations‐>Malathion Management of stable angina and acute See link for local guidelines in section coronary syndromes On Formulary 2.10 Stable angina, acute coronary syndromes, and fibrinolysis 2.10.1 MANNITOL On Formulary 2.2 Diuretics‐>2.2.5 Osmotic diuretics Mannitol On Formulary 2.2 Diuretics‐>2.2.5 Osmotic diuretics‐>MANNITOL 15.2 Local anaesthesia‐>Bupivacaine‐>BUPIVACAINE Marcain HeavyÂ® On Formulary HYDROCHLORIDE 15.2 Local anaesthesia‐>Bupivacaine‐>BUPIVACAINE MarcainÂ® On Formulary HYDROCHLORIDE

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

7.3 Contraceptives‐>7.3.1 Combined hormonal contraceptives‐ >COMBINED HORMONAL CONTRACEPTIVES‐>Oral (low and standard MarvelonÂ® On Formulary strength)‐>Ethinylestradiol with Desogestrel 11.4 Corticosteroids and other anti‐inflammatory preparations‐ MaxidexÂ® On Formulary >11.4.1 Corticosteroids‐>DEXAMETHASONE

11.4 Corticosteroids and other anti‐inflammatory preparations‐ MaxitrolÂ® On Formulary >11.4.1 Corticosteroids‐>DEXAMETHASONE‐>With antibacterials

4.6 Drugs used in nausea and vertigo‐>Domperidone and The paediatric liquid 1mg/ml is not MaxolonÂ® On Formulary metoclopramide‐>METOCLOPRAMIDE HYDROCHLORIDE kept at The Royal Free Hospital. MEBENDAZOLE On Formulary 5.5 Anthelmintics‐>5.5.1 Drugs for threadworms

Mebendazole On Formulary 5.5 Anthelmintics‐>5.5.1 Drugs for threadworms‐>MEBENDAZOLE 1.2 Antispasmodics and other drugs altering gut motility‐>Other MEBEVERINE HYDROCHLORIDE On Formulary antispasmodics 1.2 Antispasmodics and other drugs altering gut motility‐>Other Mebeverine Hydrochloride On Formulary antispasmodics‐>MEBEVERINE HYDROCHLORIDE

Only 2mg and 100mg tablets are 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy‐ formulary. 100mg tablets are MedroneÂ® On Formulary >METHYLPREDNISOLONE restricted to neurology use only.

6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ MEDROXYPROGESTERONE ACETATE On Formulary >6.4.1.2 Progestogens and progesterone receptor modulators 8.3 Sex hormones and hormone antagonists in malignant disease‐ MEDROXYPROGESTERONE ACETATE On Formulary >8.3.2 Progestogens 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ MEFENAMIC ACID On Formulary steroidal anti‐inflammatory drugs 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Only tablets available at Royal Free Mefenamic Acid On Formulary steroidal anti‐inflammatory drugs‐>MEFENAMIC ACID Hospital. 8.3 Sex hormones and hormone antagonists in malignant disease‐ MegaceÂ® On Formulary >8.3.2 Progestogens‐>MEGESTROL ACETATE 8.3 Sex hormones and hormone antagonists in malignant disease‐ MEGESTROL ACETATE On Formulary >8.3.2 Progestogens MELPHALAN On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs

Menadiol Phosphate On Formulary 9.6 Vitamins‐>9.6.6 Vitamin K‐>MENADIOL SODIUM PHOSPHATE MENADIOL SODIUM PHOSPHATE On Formulary 9.6 Vitamins‐>9.6.6 Vitamin K 14.4 Vaccines and antisera‐>Meningococcal vaccines‐ Meningococcal group B vaccine On Formulary >MENINGOCOCCAL VACCINES

14.4 Vaccines and antisera‐>Haemophilus type b conjugate vaccine‐ MenitorixÂ® On Formulary >HAEMOPHILUS TYPE B CONJUGATE VACCINE 14.4 Vaccines and antisera‐>Meningococcal vaccines‐ >MENINGOCOCCAL VACCINES‐>Meningococcal group C conjugate Menjugate KitÂ® On Formulary vaccine

Menthol and Eucalyptus Inhalation, BP 1980 On Formulary 3.8 Aromatic inhalations MEPTAZINOL On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics Only the tablets are kept at The Royal MeptidÂ® On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>MEPTAZINOL Free Hospital. MERCAPTOPURINE On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites

7.3 Contraceptives‐>7.3.1 Combined hormonal contraceptives‐ >COMBINED HORMONAL CONTRACEPTIVES‐>Oral (low and standard MercilonÂ® On Formulary strength)‐>Ethinylestradiol with Desogestrel MESALAZINE On Formulary 1.5 Chronic bowel disorders‐>1.5.1 Aminosalicylates 8.1 Cytotoxic drugs‐>Treatment for cytotoxic‐induced side‐effects‐ MESNA On Formulary >Urothelial toxicity 8.1 Cytotoxic drugs‐>Treatment for cytotoxic‐induced side‐effects‐ Mesna On Formulary >Urothelial toxicity‐>MESNA 10.2 Drugs used in neuromuscular disorders‐>10.2.1 Drugs that enhance neuromuscular transmission‐>Anticholinesterases‐ MestinonÂ® On Formulary >PYRIDOSTIGMINE BROMIDE 13.2 Emollient and barrier preparations‐>13.2.2 Barrier preparations‐ MetaniumÂ® On Formulary >Proprietary barrier preparations Unlicensed medicine. Availbale on a METARAMINOL On Formulary 2.7 Sympathomimetics‐>2.7.2 Vasoconstrictor sympathomimetics named patient basis only. 2.7 Sympathomimetics‐>2.7.2 Vasoconstrictor sympathomimetics‐ Unlicensed medicine. Available on a Metaraminol On Formulary >METARAMINOL named patient basis only. 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.2 Metformin On Formulary Biguanides‐>METFORMIN HYDROCHLORIDE

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.2 METFORMIN HYDROCHLORIDE On Formulary Biguanides 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>METHADONE Methadone On Formulary HYDROCHLORIDE Managing opiate addiction 4.10 Drugs used in substance dependence‐>4.10.3 Opioid dependence‐>Opioid substitution therapy‐>METHADONE Methadone On Formulary HYDROCHLORIDE Managing opiate addiction

METHADONE HYDROCHLORIDE On Formulary 3.9 Cough preparations‐>3.9.1 Cough suppressants‐>Palliative care METHADONE HYDROCHLORIDE On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics Managing opiate addiction 4.10 Drugs used in substance dependence‐>4.10.3 Opioid METHADONE HYDROCHLORIDE On Formulary dependence‐>Opioid substitution therapy Managing opiate addiction 3.9 Cough preparations‐>3.9.1 Cough suppressants‐>Palliative care‐ Methadone Linctus On Formulary >METHADONE HYDROCHLORIDE 10.2 Drugs used in neuromuscular disorders‐>10.2.2 Skeletal muscle METHOCARBAMOL On Formulary relaxants‐>Other muscle relaxants METHOTREXATE On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites

Methotrexate On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites‐>METHOTREXATE 13.5 Preparations for eczema and psoriasis‐>13.5.3 Drugs affecting METHOTREXATE On Formulary the immune response 2.5 Hypertension and heart failure‐>2.5.2 Centrally acting METHYLDOPA On Formulary antihypertensive drugs 2.5 Hypertension and heart failure‐>2.5.2 Centrally acting Methyldopa On Formulary antihypertensive drugs‐>METHYLDOPA METHYLPREDNISOLONE On Formulary 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy 4.6 Drugs used in nausea and vertigo‐>Domperidone and Metoclopramide On Formulary metoclopramide‐>METOCLOPRAMIDE HYDROCHLORIDE

4.6 Drugs used in nausea and vertigo‐>Domperidone and The modified release capsules are not METOCLOPRAMIDE HYDROCHLORIDE On Formulary metoclopramide kept at The Royal Free Hospital. METOLAZONE On Formulary 2.2 Diuretics‐>2.2.1 Thiazides and related diuretics 6.7 Other endocrine drugs‐>6.7.3 Cushing's Syndrome‐ MetopironeÂ® On Formulary >METYRAPONE Metoprolol injection restricted to METOPROLOL TARTRATE On Formulary 2.4 Beta‐adrenoceptor blocking drugs cardiology and ITU only. Metoprolol injection restricted to Metoprolol Tartrate On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>METOPROLOL TARTRATE cardiology and ITU only. MetosynÂ® On Formulary 13.4 Topical corticosteroids‐>FLUOCINONIDE

METRONIDAZOLE On Formulary 5.1 Antibacterial drugs‐>5.1.11 Metronidazole and tinidazole 5.1 Antibacterial drugs‐>5.1.11 Metronidazole and tinidazole‐ Metronidazole On Formulary >METRONIDAZOLE METRONIDAZOLE On Formulary 5.4 Antiprotozoal drugs‐>5.4.2 Amoebicides 13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial preparations‐>13.10.1.2 Antibacterial preparations also used METRONIDAZOLE On Formulary systemically METYRAPONE On Formulary 6.7 Other endocrine drugs‐>6.7.3 Cushing's Syndrome 6.6 Drugs affecting bone metabolism‐>6.6.1 Calcitonin and Only calcitonin injections kept at MiacalcicÂ® On Formulary parathyroid hormone‐>CALCITONIN (SALMON)/SALCATONIN Royal Free Hospital Administration of enemas or Micolette Micro‐enemaÂ® On Formulary 1.6 Laxatives‐>1.6.4 Osmotic laxatives‐>SODIUM CITRATE (RECTAL) suppositories

12.3 Drugs acting on the oropharynx‐>12.3.2 Oropharyngeal anti‐ MICONAZOLE On Formulary infective drugs‐>Oropharyngeal fungal infections

7.3 Contraceptives‐>7.3.1 Combined hormonal contraceptives‐ >COMBINED HORMONAL CONTRACEPTIVES‐>Oral (low and standard Microgynon 30Â® On Formulary strength)‐>Ethinylestradiol with Levonorgestrel

7.3 Contraceptives‐>7.3.2 Progestogen‐only contraceptives‐>7.3.2.1 Oral progestogen‐only contraceptives‐>ORAL PROGESTOGEN‐ONLY MicronorÂ® On Formulary CONTRACEPTIVES

MIDAZOLAM On Formulary 4.8 Antiepileptic drugs‐>4.8.2 Drugs used in status epilepticus 15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ MIDAZOLAM On Formulary operative drugs‐>15.1.4.1 Benzodiazepines Status epilepticus

15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ Midazolam On Formulary operative drugs‐>15.1.4.1 Benzodiazepines‐>MIDAZOLAM Status Epilepticus 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.3 Allergic emergencies‐>Anaphylaxis‐ MinijetÂ® Adrenaline 1 in 10â€‰000 On Formulary >ADRENALINE/EPINEPHRINE‐>Intravenous

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.3 Allergic emergencies‐>Anaphylaxis‐ MinijetÂ® Adrenaline 1 in 1000 On Formulary >ADRENALINE/EPINEPHRINE‐>Intramuscular or subcutaneous 15.1 General anaesthesia‐>15.1.3 Antimuscarinic drugs‐>ATROPINE MinijetÂ® Atropine On Formulary SULFATE

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐>Ventricular MinijetÂ® Lignocaine On Formulary arrhythmias‐>LIDOCAINE HYDROCHLORIDE

MinijetÂ® Naloxone On Formulary Specific drugs‐>Analgesics (opioid)‐>NALOXONE HYDROCHLORIDE

9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ MinijetÂ® Sodium Bicarbonate On Formulary >Bicarbonate and lactate‐>SODIUM BICARBONATE 11.5 Mydriatics and cycloplegics‐>Antimuscarinics‐>ATROPINE MinimsÂ® Atropine Sulphate On Formulary SULFATE‐>Single use 11.3 Anti‐infective eye preparations‐>11.3.1 Antibacterials‐ MinimsÂ® Chloramphenicol On Formulary >CHLORAMPHENICOL‐>Single use 11.5 Mydriatics and cycloplegics‐>Antimuscarinics‐ MinimsÂ® Cyclopentolate Hydrochloride On Formulary >CYCLOPENTOLATE HYDROCHLORIDE‐>Single use

11.8 Miscellaneous ophthalmic preparations‐>11.8.2 Ocular diagnostic and peri‐operative preparations and photodynamic 1% fluorescein sodium is not kept at MinimsÂ® Fluorescein Sodium On Formulary treatment‐>Ocular diagnostic preparations‐>FLUORESCEIN SODIUM RFH.

MinimsÂ® Oxybuprocaine Hydrochloride On Formulary 11.7 Local anaesthetics‐>OXYBUPROCAINE HYDROCHLORIDE 11.5 Mydriatics and cycloplegics‐>Sympathomimetics‐ MinimsÂ® Phenylephrine Hydrochloride On Formulary >PHENYLEPHRINE HYDROCHLORIDE‐>Single use

11.4 Corticosteroids and other anti‐inflammatory preparations‐ MinimsÂ® Prednisolone Sodium Phosphate On Formulary >11.4.1 Corticosteroids‐>PREDNISOLONE‐>Single use

MinimsÂ® Proxymetacaine On Formulary 11.7 Local anaesthetics‐>PROXYMETACAINE HYDROCHLORIDE

11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, MinimsÂ® Saline On Formulary ocular lubricants, and astringents‐>SODIUM CHLORIDE‐>Single use MinimsÂ® Tetracaine Hydrochloride On Formulary 11.7 Local anaesthetics‐>TETRACAINE HYDROCHLORIDE 0.5% eye drops not kept at RFH. 11.5 Mydriatics and cycloplegics‐>Antimuscarinics‐>TROPICAMIDE‐ MinimsÂ® Tropicamide On Formulary >Single use

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ MinitranÂ® On Formulary >2.6.1 Nitrates‐>GLYCERYL TRINITRATE‐>Transdermal preparations 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.1 MinodiabÂ® On Formulary Sulfonylureas‐>GLIPIZIDE 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator MINOXIDIL On Formulary antihypertensive drugs

11.8 Miscellaneous ophthalmic preparations‐>11.8.2 Ocular diagnostic and peri‐operative preparations and photodynamic Miochol‐EÂ® On Formulary treatment‐>Ocular peri‐operative drugs‐>ACETYLCHOLINE CHLORIDE 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor MirapexinÂ® On Formulary agonists‐>PRAMIPEXOLE 7.3 Contraceptives‐>7.3.2 Progestogen‐only contraceptives‐>7.3.2.3 Intra‐uterine progestogen‐only device‐>INTRA‐UTERINE MirenaÂ® On Formulary PROGESTOGEN‐ONLY SYSTEM

MIRTAZAPINE On Formulary 4.3 Antidepressant drugs‐>4.3.4 Other antidepressant drugs 4.3 Antidepressant drugs‐>4.3.4 Other antidepressant drugs‐ Mirtazapine On Formulary >MIRTAZAPINE 1.3 Antisecretory drugs and mucosal protectants‐>1.3.4 Prostaglandin MISOPROSTOL On Formulary analogues 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic MITOMYCIN On Formulary antibiotics 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic Mitomycin C KyowaÂ® On Formulary antibiotics‐>MITOMYCIN Mitotane On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs

MITOTANE On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Mitotane 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic MITOXANTRONE On Formulary antibiotics 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic Mitoxantrone On Formulary antibiotics‐>MITOXANTRONE

15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ MivacronÂ® On Formulary >Non‐depolarising neuromuscular blocking drugs‐>MIVACURIUM

15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ MIVACURIUM On Formulary >Non‐depolarising neuromuscular blocking drugs

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Modisal XLÂ® On Formulary >2.6.1 Nitrates‐>ISOSORBIDE MONONITRATE‐>Modified release A2.3 Specialised formulas‐>A2.3.2 Specialised formulas for specific Modulen IBDÂ® On Formulary clinical conditions 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ MOMETASONE FUROATE On Formulary >Corticosteroids

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

MOMETASONE FUROATE On Formulary 13.4 Topical corticosteroids

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Monomil XLÂ® On Formulary >2.6.1 Nitrates‐>ISOSORBIDE MONONITRATE‐>Modified release

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Monosorb XL 60Â® On Formulary >2.6.1 Nitrates‐>ISOSORBIDE MONONITRATE‐>Modified release 3.3 Cromoglicate and related therapy, leukotriene receptor antagonists, and phosphodiesterase type‐4 inhibitors‐>3.3.2 MONTELUKAST On Formulary Leukotriene receptor antagonists 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>MORPHINE SALTS‐ Only the 10mg suppositories are kept Morphine On Formulary >Suppositories at the RFH. 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>MORPHINE SALTS‐>Oral Morphine Oral Solutions On Formulary solutions MORPHINE SALTS On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>MORPHINE SALTS‐ Morphine Sulfate On Formulary >Injections 4.6 Drugs used in nausea and vertigo‐>Domperidone and MotiliumÂ® On Formulary metoclopramide‐>DOMPERIDONE MovicolÂ® On Formulary 1.6 Laxatives‐>1.6.4 Osmotic laxatives‐>MACROGOLS MovicolÂ® Paediatric On Formulary 1.6 Laxatives‐>1.6.4 Osmotic laxatives‐>MACROGOLS

MoviprepÂ® On Formulary 1.6 Laxatives‐>1.6.5 Bowel cleansing preparations‐>MACROGOLS 2.5 Hypertension and heart failure‐>2.5.2 Centrally acting MOXONIDINE On Formulary antihypertensive drugs 2.5 Hypertension and heart failure‐>2.5.2 Centrally acting Moxonidine On Formulary antihypertensive drugs‐>MOXONIDINE 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>MORPHINE SALTS‐>Modified‐ MST ContinusÂ® On Formulary release 12‐hourly oral preparations

1.1 Dyspepsia and gastro‐oesophageal reflux disease‐>1.1.1 Antacids and simeticone‐>Aluminium‐ and magnesium‐containing antacids‐ MucogelÂ® On Formulary >ALUMINIUM HYDROXIDE‐>Co‐magaldrox

7.4 Drugs for genito‐urinary disorders‐>7.4.5 Drugs for erectile MUSEÂ® On Formulary dysfunction‐>Alprostadil‐>ALPROSTADIL‐>Urethral application 8.2 Drugs affecting the immune response‐>8.2.1 Antiproliferative MYCOPHENOLATE MOFETIL On Formulary immunosuppressants

MydriacylÂ® On Formulary 11.5 Mydriatics and cycloplegics‐>Antimuscarinics‐>TROPICAMIDE 11.5 Mydriatics and cycloplegics‐>Antimuscarinics‐ MydrilateÂ® On Formulary >CYCLOPENTOLATE HYDROCHLORIDE MyleranÂ® On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs‐>BUSULFAN 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Gold‐>SODIUM MyocrisinÂ® On Formulary AUROTHIOMALATE NABILONE On Formulary 4.6 Drugs used in nausea and vertigo‐>Cannabinoid

Nabilone On Formulary 4.6 Drugs used in nausea and vertigo‐>Cannabinoid‐>NABILONE 6.7 Other endocrine drugs‐>6.7.2 Drugs affecting gonadotrophins‐ NAFARELIN On Formulary >Gonadorelin analogues 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.4 Peripheral vasodilators and related drugs‐>NAFTIDROFURYL Naftidrofuryl On Formulary OXALATE

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ NAFTIDROFURYL OXALATE On Formulary >2.6.4 Peripheral vasodilators and related drugs 4.10 Drugs used in substance dependence‐>4.10.3 Opioid dependence‐>Opioid‐receptor antagonists‐>NALTREXONE NalorexÂ® On Formulary HYDROCHLORIDE

Naloxone On Formulary Specific drugs‐>Analgesics (opioid)‐>NALOXONE HYDROCHLORIDE NALOXONE HYDROCHLORIDE On Formulary Specific drugs‐>Analgesics (opioid) 15.1 General anaesthesia‐>15.1.7 Antagonists for central and NALOXONE HYDROCHLORIDE On Formulary respiratory depression 4.10 Drugs used in substance dependence‐>4.10.3 Opioid NALTREXONE HYDROCHLORIDE On Formulary dependence‐>Opioid‐receptor antagonists NANDROLONE On Formulary 6.4 Sex hormones‐>6.4.3 Anabolic steroids 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ NaprosynÂ® On Formulary steroidal anti‐inflammatory drugs‐>NAPROXEN 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ NAPROXEN On Formulary steroidal anti‐inflammatory drugs 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Naproxen On Formulary steroidal anti‐inflammatory drugs‐>NAPROXEN 4.3 Antidepressant drugs‐>4.3.2 Monoamine‐oxidase inhibitors‐ NardilÂ® On Formulary >PHENELZINE 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ NasacortÂ® On Formulary >Corticosteroids‐>TRIAMCINOLONE ACETONIDE 12.2 Drugs acting on the nose‐>12.2.3 Nasal preparations for Nasal staphylococci On Formulary infection MRSA screening procedure

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

12.2 Drugs acting on the nose‐>12.2.3 Nasal preparations for NaseptinÂ® On Formulary infection‐>Nasal staphylococci 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ NasofanÂ® On Formulary >Corticosteroids‐>FLUTICASONE PROPIONATE 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ NasonexÂ® On Formulary >Corticosteroids‐>MOMETASONE FUROATE 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other NATEGLINIDE On Formulary antidiabetic drugs 2.2 Diuretics‐>2.2.1 Thiazides and related diuretics‐>INDAPAMIDE‐ Natrilix SRÂ® On Formulary >Modified release

NatrilixÂ® On Formulary 2.2 Diuretics‐>2.2.1 Thiazides and related diuretics‐>INDAPAMIDE 8.1 Cytotoxic drugs‐>8.1.4 Vinca alkaloids and etoposide‐ NavelbineÂ® On Formulary >VINORELBINE Capsules are non‐formulary 6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists‐ NebidoÂ® On Formulary >TESTOSTERONE AND ESTERS‐>Intramuscular

11.4 Corticosteroids and other anti‐inflammatory preparations‐ NEDOCROMIL SODIUM On Formulary >11.4.2 Other anti‐inflammatory preparations 4.7 Analgesics‐>4.7.1 Non‐opioid analgesics and compound analgesic NEFOPAM HYDROCHLORIDE On Formulary preparations

Neomycin On Formulary 5.1 Antibacterial drugs‐>5.1.4 Aminoglycosides‐>NEOMYCIN SULFATE NEOMYCIN SULFATE On Formulary 5.1 Antibacterial drugs‐>5.1.4 Aminoglycosides 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐infective NEOMYCIN SULFATE On Formulary preparations

8.2 Drugs affecting the immune response‐>8.2.2 Corticosteroids and NeoralÂ® On Formulary other immunosuppressants‐>CICLOSPORIN

9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in hypoplastic, haemolytic, and renal anaemias‐>Erythropoietins‐ NeoRecormonÂ® On Formulary >EPOETIN ALFA, BETA, and ZETA‐>Epoetin beta

10.2 Drugs used in neuromuscular disorders‐>10.2.1 Drugs that NEOSTIGMINE On Formulary enhance neuromuscular transmission‐>Anticholinesterases 10.2 Drugs used in neuromuscular disorders‐>10.2.1 Drugs that enhance neuromuscular transmission‐>Anticholinesterases‐ Neostigmine On Formulary >NEOSTIGMINE

15.1 General anaesthesia‐>15.1.6 Drugs for reversal of neuromuscular Neostigmine On Formulary blockade‐>Anticholinesterases‐>NEOSTIGMINE METILSULFATE 15.1 General anaesthesia‐>15.1.6 Drugs for reversal of neuromuscular NEOSTIGMINE METILSULFATE On Formulary blockade‐>Anticholinesterases

13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for NeotigasonÂ® On Formulary psoriasis‐>Oral retinoids for psoriasis‐>ACITRETIN A2.3 Specialised formulas‐>A2.3.2 Specialised formulas for specific NeproÂ® On Formulary clinical conditions

Only Oily cream and Ointment are NerisoneÂ® On Formulary 13.4 Topical corticosteroids‐>DIFLUCORTOLONE VALERATE available at the Royal Free Hospital. 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Gabapentin NeurontinÂ® On Formulary and pregabalin‐>GABAPENTIN 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Non‐nucleoside reverse NEVIRAPINE On Formulary transcriptase inhibitors As per HIV guidelines. 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ NICORANDIL On Formulary >2.6.3 Other antianginal drugs

4.10 Drugs used in substance dependence‐>4.10.2 Nicotine NicoretteÂ® On Formulary dependence‐>Nicotine replacement therapy‐>NICOTINE NICOTINAMIDE On Formulary 9.6 Vitamins‐>9.6.2 Vitamin B group 4.10 Drugs used in substance dependence‐>4.10.2 Nicotine NICOTINE On Formulary dependence‐>Nicotine replacement therapy

4.10 Drugs used in substance dependence‐>4.10.2 Nicotine NicotinellÂ® On Formulary dependence‐>Nicotine replacement therapy‐>NICOTINE 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ NIFEDIPINE On Formulary >2.6.2 Calcium‐channel blockers

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Nifedipine On Formulary >2.6.2 Calcium‐channel blockers‐>NIFEDIPINE 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase NILOTINIB On Formulary inhibitors Prior funding approval required 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ NIMODIPINE On Formulary >2.6.2 Calcium‐channel blockers

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ NimotopÂ® On Formulary >2.6.2 Calcium‐channel blockers‐>NIMODIPINE

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase NINTEDANIB On Formulary inhibitors 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Pentostatin‐ NipentÂ® On Formulary >PENTOSTATIN

NITRAZEPAM On Formulary 4.1 Hypnotics and anxiolytics‐>4.1.1 Hypnotics‐>Benzodiazepines 4.1 Hypnotics and anxiolytics‐>4.1.1 Hypnotics‐>Benzodiazepines‐ Nitrazepam On Formulary >NITRAZEPAM

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Nitro‐DurÂ® On Formulary >2.6.1 Nitrates‐>GLYCERYL TRINITRATE‐>Transdermal preparations 15mg patch not available.

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ NitrocineÂ® On Formulary >2.6.1 Nitrates‐>GLYCERYL TRINITRATE‐>Parenteral preparations NITROFURANTOIN On Formulary 5.1 Antibacterial drugs‐>5.1.13 Urinary‐tract infections 5.1 Antibacterial drugs‐>5.1.13 Urinary‐tract infections‐ Nitrofurantoin On Formulary >NITROFURANTOIN 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.1 Nitrates‐>GLYCERYL TRINITRATE‐>Short‐acting tablets and Nitrolingual PumpsprayÂ® On Formulary sprays 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.1 Nitrates‐>GLYCERYL TRINITRATE‐>Short‐acting tablets and NitrominÂ® On Formulary sprays

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ NitronalÂ® On Formulary >2.6.1 Nitrates‐>GLYCERYL TRINITRATE‐>Parenteral preparations

15.1 General anaesthesia‐>15.1.2 Inhalational anaesthetics‐>Nitrous Procedure for the Administration of NITROUS OXIDE On Formulary oxide Entonox for Pain Relief

There are non‐proprietary preparations available at the Royal 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for Free Hospital but not listed in the Non‐proprietary preparations On Formulary psoriasis‐>Topical preparations for psoriasis‐>Tars‐>TARS eBNF, contact Pharmacy for details.

NORADRENALINE/NOREPINEPHRINE On Formulary 2.7 Sympathomimetics‐>2.7.2 Vasoconstrictor sympathomimetics 2.7 Sympathomimetics‐>2.7.2 Vasoconstrictor sympathomimetics‐ Noradrenaline/Norepinephrine On Formulary >NORADRENALINE/NOREPINEPHRINE 15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ >Non‐depolarising neuromuscular blocking drugs‐>VECURONIUM NorcuronÂ® On Formulary BROMIDE

6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ NORETHISTERONE On Formulary >6.4.1.2 Progestogens and progesterone receptor modulators 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.2 Progestogens and progesterone receptor modulators‐ Norethisterone On Formulary >NORETHISTERONE 8.3 Sex hormones and hormone antagonists in malignant disease‐ NORETHISTERONE On Formulary >8.3.2 Progestogens

7.3 Contraceptives‐>7.3.1 Combined hormonal contraceptives‐ >COMBINED HORMONAL CONTRACEPTIVES‐>Oral (low and standard NoriminÂ® On Formulary strength)‐>Ethinylestradiol with Norethisterone NORMAL IMMUNOGLOBULIN On Formulary 14.5 Immunoglobulins‐>14.5.1 Normal immunoglobulin 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.1 NormasolÂ® On Formulary Alcohols and saline‐>SODIUM CHLORIDE

NormosangÂ® On Formulary 9.8 Metabolic disorders‐>9.8.2 Acute porphyrias‐>HAEM ARGINATE 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors‐ NorvirÂ® On Formulary >RITONAVIR As per HIV guidelines.

6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.2 Intermediate‐ and NovoMixÂ® 30 On Formulary long‐acting insulins‐>Biphasic insulins‐>BIPHASIC INSULIN ASPART 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.1 Short‐acting NovoRapidÂ® On Formulary insulins‐>INSULIN ASPART Nu‐SealsÂ® Aspirin On Formulary 2.9 Antiplatelet drugs‐>ASPIRIN (antiplatelet) 4.7 Analgesics‐>4.7.1 Non‐opioid analgesics and compound analgesic Nu‐SealsÂ® Aspirin On Formulary preparations‐>ASPIRIN A2.1 Enteral feeds (non‐disease specific)‐>A2.1.1 Enteral feeds (non‐ disease specific): less than 5Â g protein/100Â mL‐>A2.1.1.1 Enteral feeds: 1Â kcal/mL and less than 5Â g protein/100Â mL‐>Soya protein NutrisonÂ® Soya On Formulary formula 1.9 Drugs affecting intestinal secretions‐>1.9.4 Pancreatin‐ Nutrizym 22Â® On Formulary >PANCREATIN‐>Higher‐strength preparations

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.1 Oestrogens and HRT‐>OESTROGENS FOR HRT‐>Estradiol with NuvelleÂ® Continuous On Formulary progestogen Only Cream available at the Royal Nystaform‐HCÂ® On Formulary 13.4 Topical corticosteroids‐>HYDROCORTISONE‐>With antimicrobials Free Hospital.

12.3 Drugs acting on the oropharynx‐>12.3.2 Oropharyngeal anti‐ NystanÂ® On Formulary infective drugs‐>Oropharyngeal fungal infections‐>NYSTATIN

12.3 Drugs acting on the oropharynx‐>12.3.2 Oropharyngeal anti‐ NYSTATIN On Formulary infective drugs‐>Oropharyngeal fungal infections 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal NYSTATIN On Formulary preparations OcclusalÂ® On Formulary 13.7 Preparations for warts and calluses‐>SALICYLIC ACID

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.2 Posterior pituitary hormones and antagonists‐>Posterior pituitary OctimÂ® On Formulary hormones‐>DESMOPRESSIN

8.3 Sex hormones and hormone antagonists in malignant disease‐ OCTREOTIDE On Formulary >8.3.4 Hormone antagonists‐>8.3.4.3 Somatostatin analogues 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ OESTROGENS FOR HRT On Formulary >6.4.1.1 Oestrogens and HRT

7.2 Treatment of vaginal and vulval conditions‐>7.2.1 Preparations for OESTROGENS, TOPICAL On Formulary vaginal and vulval changes‐>Topical HRT for vaginal atrophy

13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐ Only Shower emollient (gel) is OilatumÂ® On Formulary >Proprietary emollient preparations available at the Royal Free Hospital. 1.7 Local preparations for anal and rectal disorders‐>1.7.3 Rectal Oily Phenol Injection, BP On Formulary sclerosants‐>PHENOL Olive Oil On Formulary 12.1 Drugs acting on the ear‐>12.1.3 Removal of earwax OLSALAZINE SODIUM On Formulary 1.5 Chronic bowel disorders‐>1.5.1 Aminosalicylates

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ OMALIZUMAB On Formulary >3.4.2 Allergen immunotherapy‐>Omalizumab

7.3 Contraceptives‐>7.3.2 Progestogen‐only contraceptives‐>7.3.2.1 ORAL PROGESTOGEN‐ONLY CONTRACEPTIVES On Formulary Oral progestogen‐only contraceptives

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

WHO Oral Rehydration Powder is not 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and kept at RFH but all ingredients are electrolyte imbalance‐>9.2.1.2 Oral sodium and water‐>Oral available individually (i.e. sodium rehydration therapy (ORT)‐>ORAL REHYDRATION SALTS (ORS)‐>WHO chloride, potassium chloride, sodium Oral Rehydration Salts On Formulary formulation citrate and anhydrous glucose). 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and electrolyte imbalance‐>9.2.1.2 Oral sodium and water‐>Oral ORAL REHYDRATION SALTS (ORS) On Formulary rehydration therapy (ORT) 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>MORPHINE SALTS‐>Oral OramorphÂ® On Formulary solutions 4.9 Drugs used in parkinsonism and related disorders‐>4.9.2 ORPHENADRINE HYDROCHLORIDE On Formulary Antimuscarinic drugs used in parkinsonism 4.9 Drugs used in parkinsonism and related disorders‐>4.9.2 Antimuscarinic drugs used in parkinsonism‐>ORPHENADRINE Orphenadrine Hydrochloride On Formulary HYDROCHLORIDE

A2.1 Enteral feeds (non‐disease specific)‐>A2.1.1 Enteral feeds (non‐ disease specific): less than 5Â g protein/100Â mL‐>A2.1.1.1 Enteral OsmoliteÂ® On Formulary feeds: 1Â kcal/mL and less than 5Â g protein/100Â mL

A2.1 Enteral feeds (non‐disease specific)‐>A2.1.2 Enteral feeds (non‐ disease specific): 5Â g (or more) protein/100Â mL‐>A2.1.2.1 Enteral OsmoliteÂ® 1.5â€‰kcal On Formulary feeds: 1.5Â kcal/mL and 5Â g (or more) protein/100Â mL Other reagent strips available for urinalysis 6.1 Drugs used in diabetes‐>6.1.6 Diagnostic and monitoring devices Only Combur 3 and Uristix kept at the include: On Formulary for diabetes mellitus‐>Urinalysis RFH 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ inflammatory preparations‐>Corticosteroids‐>DEXAMETHASONE‐ OtomizeÂ® On Formulary >With antibacterial

12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐infective OtomizeÂ® On Formulary preparations‐>NEOMYCIN SULFATE‐>With corticosteroid 7.2 Treatment of vaginal and vulval conditions‐>7.2.1 Preparations for vaginal and vulval changes‐>Topical HRT for vaginal atrophy‐ OvestinÂ® On Formulary >OESTROGENS, TOPICAL

3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective OxisÂ® On Formulary beta2 agonists‐>FORMOTEROL FUMARATE 2.4 Beta‐adrenoceptor blocking drugs‐>OXPRENOLOL Oxprenolol On Formulary HYDROCHLORIDE OXPRENOLOL HYDROCHLORIDE On Formulary 2.4 Beta‐adrenoceptor blocking drugs OXYBUPROCAINE HYDROCHLORIDE On Formulary 11.7 Local anaesthetics

7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary OXYBUTYNIN HYDROCHLORIDE On Formulary frequency, enuresis, and incontinence‐>Urinary incontinence 7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary frequency, enuresis, and incontinence‐>Urinary incontinence‐ Oxybutynin Hydrochloride On Formulary >OXYBUTYNIN HYDROCHLORIDE Only 2.5mg tablets kept OXYCODONE HYDROCHLORIDE On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>OXYCODONE OxyContinÂ® On Formulary HYDROCHLORIDE‐>Modified release 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>OXYCODONE OxyNormÂ® On Formulary HYDROCHLORIDE OXYTETRACYCLINE On Formulary 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines

Oxytetracycline On Formulary 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines‐>OXYTETRACYCLINE

Royal Free Maternity Unit Guideline OXYTOCIN On Formulary 7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics on Massive Obstetric Haemorrhage PabrinexÂ® On Formulary 9.6 Vitamins‐>9.6.2 Vitamin B group‐>THIAMINE A2.4 Feed supplements‐>A2.4.2 Fibre, vitamin, and mineral Paediatric SeravitÂ® On Formulary supplements‐>Vitamin and Mineral supplements

6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and PAMIDRONATE DISODIUM On Formulary other drugs affecting bone metabolism‐>Bisphosphonates 6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and other drugs affecting bone metabolism‐>Bisphosphonates‐ Pamidronate disodium On Formulary >PAMIDRONATE DISODIUM PANCREATIN On Formulary 1.9 Drugs affecting intestinal secretions‐>1.9.4 Pancreatin 1.9 Drugs affecting intestinal secretions‐>1.9.4 Pancreatin‐ Pancrex VÂ® On Formulary >PANCREATIN 15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ >Non‐depolarising neuromuscular blocking drugs‐>PANCURONIUM Pancuronium On Formulary BROMIDE

15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ PANCURONIUM BROMIDE On Formulary >Non‐depolarising neuromuscular blocking drugs

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐ PanOxylÂ® On Formulary >Benzoyl peroxide and azelaic acid‐>BENZOYL PEROXIDE PAPAVERETUM On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics Papaveretum On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>PAPAVERETUM 4.7 Analgesics‐>4.7.1 Non‐opioid analgesics and compound analgesic PARACETAMOL On Formulary preparations 4.7 Analgesics‐>4.7.1 Non‐opioid analgesics and compound analgesic Paracetamol On Formulary preparations‐>PARACETAMOL 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐>Non‐ Paraffin, White Soft, BP On Formulary proprietary emollient preparations 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐>Non‐ Paraffin, Yellow Soft, BP On Formulary proprietary emollient preparations 11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, PARAFFIN, YELLOW, SOFT On Formulary ocular lubricants, and astringents

Metoject is not available at RFH. The pharmacy production unit 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that manufactures methotrexate pre‐filled suppress the rheumatic disease process‐>Drugs affecting the immune syringes for parenteral Parenteral preparations On Formulary response‐>METHOTREXATE administration.

PARENTERAL PROGESTOGEN‐ONLY 7.3 Contraceptives‐>7.3.2 Progestogen‐only contraceptives‐>7.3.2.2 CONTRACEPTIVES On Formulary Parenteral progestogen‐only contraceptives 6.7 Other endocrine drugs‐>6.7.1 Bromocriptine and other ParlodelÂ® On Formulary dopaminergic drugs‐>BROMOCRIPTINE 1mg tablets are non‐formulary 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake PAROXETINE On Formulary inhibitors 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake Paroxetine On Formulary inhibitors‐>PAROXETINE ParvolexÂ® On Formulary Specific drugs‐>Analgesics (non‐opioid)‐>ACETYLCYSTEINE PeditraceÂ® On Formulary 9.3 Intravenous nutrition‐>Supplementary preparations

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ PEGVISOMANT On Formulary >Anterior pituitary hormones‐>Growth hormone receptor antagonists 9.8 Metabolic disorders‐>9.8.1 Drugs used in metabolic disorders‐ PENICILLAMINE On Formulary >Wilson's disease

10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that PENICILLAMINE On Formulary suppress the rheumatic disease process‐>Penicillamine 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Penicillamine‐ Penicillamine On Formulary >PENICILLAMINE

PentasaÂ® On Formulary 1.5 Chronic bowel disorders‐>1.5.1 Aminosalicylates‐>MESALAZINE Pentostatin On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs

PENTOSTATIN On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Pentostatin

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ PENTOXIFYLLINE On Formulary >2.6.4 Peripheral vasodilators and related drugs 1.2 Antispasmodics and other drugs altering gut motility‐>Other PEPPERMINT OIL On Formulary antispasmodics A2.1 Enteral feeds (non‐disease specific)‐>A2.1.1 Enteral feeds (non‐ disease specific): less than 5Â g protein/100Â mL‐>A2.1.1.1 Enteral feeds: 1Â kcal/mL and less than 5Â g protein/100Â mL‐>Peptide‐ PeptamenÂ® On Formulary based formula Ready to hang only available 2.1 Positive inotropic drugs‐>2.1.2 Phosphodiesterase type‐3 PerfanÂ® On Formulary inhibitors‐>ENOXIMONE 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor PERGOLIDE On Formulary agonists 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor Pergolide On Formulary agonists‐>PERGOLIDE 1mg tablets are not kept at the RFH. 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.1 Antihistamines‐>Sedating antihistamines‐>CYPROHEPTADINE PeriactinÂ® On Formulary HYDROCHLORIDE 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme Perindopril On Formulary inhibitors‐>PERINDOPRIL ERBUMINE 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme PERINDOPRIL ERBUMINE On Formulary inhibitors 13.10 Anti‐infective skin preparations‐>13.10.4 Parasiticidal PERMETHRIN On Formulary preparations‐>Permethrin 13.10 Anti‐infective skin preparations‐>13.10.4 Parasiticidal Permethrin On Formulary preparations‐>Permethrin‐>PERMETHRIN

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.6 PermitabsÂ® On Formulary Oxidisers and dyes‐>POTASSIUM PERMANGANATE PersantinÂ® On Formulary 2.9 Antiplatelet drugs‐>DIPYRIDAMOLE PersantinÂ® Retard On Formulary 2.9 Antiplatelet drugs‐>DIPYRIDAMOLE‐>Modified release

Pethidine On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>PETHIDINE HYDROCHLORIDE PETHIDINE HYDROCHLORIDE On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic PharmorubicinÂ® Solution for Injection On Formulary antibiotics‐>EPIRUBICIN HYDROCHLORIDE

PHENELZINE On Formulary 4.3 Antidepressant drugs‐>4.3.2 Monoamine‐oxidase inhibitors 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.1 Antihistamines‐>Sedating antihistamines‐>PROMETHAZINE PhenerganÂ® On Formulary HYDROCHLORIDE 2.8 Anticoagulants and protamine‐>2.8.2 Oral anticoagulants‐ Should only be used in patients who PHENINDIONE On Formulary >Coumarins and phenindione are allergic to warfarin.

2.8 Anticoagulants and protamine‐>2.8.2 Oral anticoagulants‐ Should only be used in patients who Phenindione On Formulary >Coumarins and phenindione‐>PHENINDIONE are allergic to warfarin. 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ PHENOBARBITAL On Formulary >Phenobarbital and primidone 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ Phenobarbital On Formulary >Phenobarbital and primidone‐>PHENOBARBITAL 4.8 Antiepileptic drugs‐>4.8.2 Drugs used in status epilepticus‐ Phenobarbital On Formulary >PHENOBARBITAL SODIUM

PHENOBARBITAL SODIUM On Formulary 4.8 Antiepileptic drugs‐>4.8.2 Drugs used in status epilepticus 1.7 Local preparations for anal and rectal disorders‐>1.7.3 Rectal PHENOL On Formulary sclerosants 2.5 Hypertension and heart failure‐>2.5.4 Alpha‐adrenoceptor blocking drugs‐>Phaeochromocytoma‐>PHENOXYBENZAMINE Phenoxybenzamine On Formulary HYDROCHLORIDE 2.5 Hypertension and heart failure‐>2.5.4 Alpha‐adrenoceptor PHENOXYBENZAMINE HYDROCHLORIDE On Formulary blocking drugs‐>Phaeochromocytoma 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.1 Benzylpenicillin and PHENOXYMETHYLPENICILLIN On Formulary phenoxymethylpenicillin

5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.1 Benzylpenicillin and Phenoxymethylpenicillin On Formulary phenoxymethylpenicillin‐>PHENOXYMETHYLPENICILLIN 2.5 Hypertension and heart failure‐>2.5.4 Alpha‐adrenoceptor PHENTOLAMINE MESILATE On Formulary blocking drugs‐>Phaeochromocytoma 2.7 Sympathomimetics‐>2.7.2 Vasoconstrictor sympathomimetics‐ Phenylephrine On Formulary >PHENYLEPHRINE HYDROCHLORIDE

PHENYLEPHRINE HYDROCHLORIDE On Formulary 2.7 Sympathomimetics‐>2.7.2 Vasoconstrictor sympathomimetics

Phenylephrine 30% gel also available PHENYLEPHRINE HYDROCHLORIDE On Formulary 11.5 Mydriatics and cycloplegics‐>Sympathomimetics as a named doctor/patient drug.

PHENYTOIN On Formulary 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Phenytoin 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Phenytoin‐ Phenytoin On Formulary >PHENYTOIN 4.8 Antiepileptic drugs‐>4.8.2 Drugs used in status epilepticus‐ Phenytoin On Formulary >PHENYTOIN SODIUM

PHENYTOIN SODIUM On Formulary 4.8 Antiepileptic drugs‐>4.8.2 Drugs used in status epilepticus A2.7 Nutritional supplements for metabolic diseases‐ Phlexy‐VitsÂ® On Formulary >Phenylketonuria PHOLCODINE On Formulary 3.9 Cough preparations‐>3.9.1 Cough suppressants

Pholcodine Linctus, BP On Formulary 3.9 Cough preparations‐>3.9.1 Cough suppressants‐>PHOLCODINE

Phosphate‐SandozÂ® On Formulary 9.5 Minerals‐>9.5.2 Phosphorus‐>9.5.2.1 Phosphate supplements

Phosphates On Formulary 9.5 Minerals‐>9.5.2 Phosphorus‐>9.5.2.1 Phosphate supplements Administration of enemas or PHOSPHATES (RECTAL) On Formulary 1.6 Laxatives‐>1.6.4 Osmotic laxatives suppositories 3.1 Bronchodilators‐>3.1.3 Theophylline‐>AMINOPHYLLINE‐>Modified Phyllocontin ContinusÂ® On Formulary release 2.5 Hypertension and heart failure‐>2.5.2 Centrally acting PhysiotensÂ® On Formulary antihypertensive drugs‐>MOXONIDINE Administration of Vitamin K to the PHYTOMENADIONE On Formulary 9.6 Vitamins‐>9.6.6 Vitamin K Newborn 1.6 Laxatives‐>1.6.5 Bowel cleansing preparations‐>SODIUM PicolaxÂ® On Formulary PICOSULFATE WITH MAGNESIUM CITRATE PILOCARPINE On Formulary 11.6 Treatment of glaucoma‐>Miotics Pilocarpine Hydrochloride On Formulary 11.6 Treatment of glaucoma‐>Miotics‐>PILOCARPINE 12.3 Drugs acting on the oropharynx‐>12.3.5 Treatment of dry mouth‐ PILOCARPINE HYDROCHLORIDE On Formulary >Systemic treatment

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other PIOGLITAZONE On Formulary antidiabetic drugs 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.1 Antihistamines‐>Sedating antihistamines‐>CHLORPHENAMINE PiritonÂ® On Formulary MALEATE 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ PIROXICAM On Formulary steroidal anti‐inflammatory drugs Only 10mg capsules kept at the RFH 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Piroxicam On Formulary steroidal anti‐inflammatory drugs‐>PIROXICAM Only 10mg capsules kept at the RFH 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic PIXANTRONE On Formulary antibiotics 4.7 Analgesics‐>4.7.4 Antimigraine drugs‐>4.7.4.2 Prophylaxis of PIZOTIFEN On Formulary migraine 4.7 Analgesics‐>4.7.4 Antimigraine drugs‐>4.7.4.2 Prophylaxis of Pizotifen On Formulary migraine‐>PIZOTIFEN 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Antimalarials‐ PlaquenilÂ® On Formulary >HYDROXYCHLOROQUINE SULFATE Platinum compounds On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs PlavixÂ® On Formulary 2.9 Antiplatelet drugs‐>CLOPIDOGREL

PODOPHYLLOTOXIN On Formulary 13.7 Preparations for warts and calluses‐>Anogenital warts A2.4 Feed supplements‐>A2.4.1 High‐energy supplements‐>A2.4.1.1 PolycalÂ® On Formulary High‐energy supplements: carbohydrate Only liquid kept. 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and electrolyte imbalance‐>9.2.1.1 Oral potassium‐>Management of POLYSTYRENE SULFONATE RESINS On Formulary hyperkalaemia 13.9 Shampoos and other preparations for scalp and hair conditions‐ PolytarÂ® On Formulary >Other scalp preparations 11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, POLYVINYL ALCOHOL On Formulary ocular lubricants, and astringents 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and POTASSIUM CHLORIDE On Formulary electrolyte imbalance‐>9.2.1.1 Oral potassium 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ POTASSIUM CHLORIDE On Formulary >Intravenous potassium IV Potassium Administration Policy 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid Potassium Chloride and Glucose Intravenous and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ Infusion On Formulary >Intravenous potassium‐>POTASSIUM CHLORIDE IV Potassium Administration Policy 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid Potassium Chloride and Sodium Chloride and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ Intravenous Infusion On Formulary >Intravenous potassium‐>POTASSIUM CHLORIDE IV Potassium Administration Policy 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ Potassium Chloride Concentrate, Sterile On Formulary >Intravenous potassium‐>POTASSIUM CHLORIDE IV Potassium Administration Policy 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid Potassium Chloride, Sodium Chloride, and and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ Glucose Intravenous Infusion On Formulary >Intravenous potassium‐>POTASSIUM CHLORIDE IV Potassium Administration Policy 7.4 Drugs for genito‐urinary disorders‐>7.4.3 Drugs used in urological POTASSIUM CITRATE On Formulary pain‐>Alkalinisation of urine

7.4 Drugs for genito‐urinary disorders‐>7.4.3 Drugs used in urological Potassium Citrate Mixture BP On Formulary pain‐>Alkalinisation of urine‐>POTASSIUM CITRATE 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.6 POTASSIUM PERMANGANATE On Formulary Oxidisers and dyes 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.4 POVIDONEâ€“IODINE On Formulary Iodine 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor PRAMIPEXOLE On Formulary agonists

Pravastatin On Formulary 2.12 Lipid‐regulating drugs‐>Statins‐>PRAVASTATIN SODIUM PRAVASTATIN SODIUM On Formulary 2.12 Lipid‐regulating drugs‐>Statins 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.4 Peripheral vasodilators and related drugs‐>NAFTIDROFURYL PraxileneÂ® On Formulary OXALATE 2.5 Hypertension and heart failure‐>2.5.4 Alpha‐adrenoceptor PRAZOSIN On Formulary blocking drugs 2.5 Hypertension and heart failure‐>2.5.4 Alpha‐adrenoceptor Only 500mcg and 1mg tablets Prazosin On Formulary blocking drugs‐>PRAZOSIN stocked. 7.4 Drugs for genito‐urinary disorders‐>7.4.1 Drugs for urinary PRAZOSIN On Formulary retention‐>Alpha‐blockers 11.4 Corticosteroids and other anti‐inflammatory preparations‐ Pred ForteÂ® On Formulary >11.4.1 Corticosteroids‐>PREDNISOLONE PREDNISOLONE On Formulary 1.5 Chronic bowel disorders‐>1.5.2 Corticosteroids PREDNISOLONE On Formulary 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy

Prednisolone On Formulary 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy‐>PREDNISOLONE 11.4 Corticosteroids and other anti‐inflammatory preparations‐ PREDNISOLONE On Formulary >11.4.1 Corticosteroids

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ PREDNISOLONE SODIUM PHOSPHATE On Formulary inflammatory preparations‐>Corticosteroids 1.5 Chronic bowel disorders‐>1.5.2 Corticosteroids‐>PREDNISOLONE‐ PredsolÂ® On Formulary >Rectal preparations 11.4 Corticosteroids and other anti‐inflammatory preparations‐ PredsolÂ® On Formulary >11.4.1 Corticosteroids‐>PREDNISOLONE 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ inflammatory preparations‐>Corticosteroids‐>PREDNISOLONE PredsolÂ® On Formulary SODIUM PHOSPHATE

9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency PregadayÂ® On Formulary anaemias‐>9.1.1.1 Oral iron‐>FERROUS FUMARATE‐>With folic acid

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ >Anterior pituitary hormones‐>Gonadotrophins‐>CHORIONIC PregnylÂ® On Formulary GONADOTROPHIN 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.1 Oestrogens and HRT‐>OESTROGENS FOR HRT‐>Conjugated 300 microgram tablets are not kept at PremarinÂ® On Formulary oestrogens only RFH. 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.1 Oestrogens and HRT‐>OESTROGENS FOR HRT‐>Conjugated PremiqueÂ® On Formulary oestrogens with progestogen 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.1 Oestrogens and HRT‐>OESTROGENS FOR HRT‐>Conjugated Prempak‐CÂ® On Formulary oestrogens with progestogen 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.3 Preparations On Formulary Cationic surfactants and soaps‐>CETRIMIDE Only Tisept kept at the RFH. PREPARATIONS FOR OTHER VAGINAL 7.2 Treatment of vaginal and vulval conditions‐>7.2.2 Vaginal and INFECTIONS On Formulary vulval infections‐>Other infections PREPARATIONS FOR VAGINAL AND VULVAL 7.2 Treatment of vaginal and vulval conditions‐>7.2.2 Vaginal and CANDIDIASIS On Formulary vulval infections‐>Fungal infections Prevention of infection in obstetric and 5.1 Antibacterial drugs‐>Table 2. Summary of antibacterial gynaecological surgery On Formulary prophylaxis RFH antibiotic policy in Obstetrics PRILOCAINE HYDROCHLORIDE On Formulary 15.2 Local anaesthesia‐>Prilocaine PRIMAQUINE On Formulary 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Primaquine 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ PRIMIDONE On Formulary >Phenobarbital and primidone IVIG patient registration form must be completed when initiating IVIG therapy before product can be dispensed. Consult your ward pharmacist for which brand to 14.5 Immunoglobulins‐>14.5.1 Normal immunoglobulin‐>NORMAL prescribe. IVIG patient registration PrivigenÂ® On Formulary IMMUNOGLOBULIN‐>For intravenous use form 1.2 Antispasmodics and other drugs altering gut motility‐ Pro‐BanthineÂ® On Formulary >Antimuscarinics‐>PROPANTHELINE BROMIDE Procarbazine On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs

PROCARBAZINE On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Procarbazine 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Procarbazine‐ Procarbazine On Formulary >PROCARBAZINE 4.6 Drugs used in nausea and vertigo‐>Phenothiazines and related PROCHLORPERAZINE On Formulary drugs 4.6 Drugs used in nausea and vertigo‐>Phenothiazines and related Prochlorperazine On Formulary drugs‐>PROCHLORPERAZINE 4.9 Drugs used in parkinsonism and related disorders‐>4.9.2 Antimuscarinic drugs used in parkinsonism‐>PROCYCLIDINE Procyclidine On Formulary HYDROCHLORIDE 4.9 Drugs used in parkinsonism and related disorders‐>4.9.2 PROCYCLIDINE HYDROCHLORIDE On Formulary Antimuscarinic drugs used in parkinsonism 13.10 Anti‐infective skin preparations‐>13.10.5 Preparations for Proflavine Cream, BPC On Formulary minor cuts and abrasions

6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ PROGESTERONE On Formulary >6.4.1.2 Progestogens and progesterone receptor modulators

8.2 Drugs affecting the immune response‐>8.2.2 Corticosteroids and PrografÂ® On Formulary other immunosuppressants‐>TACROLIMUS PRESCIBE BY BRAND NAME PROGUANIL HYDROCHLORIDE On Formulary 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Proguanil PROGUANIL HYDROCHLORIDE WITH ATOVAQUONE On Formulary 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Proguanil 8.2 Drugs affecting the immune response‐>8.2.4 Other ProleukinÂ® On Formulary immunomodulating drugs‐>Aldesleukin‐>ALDESLEUKIN

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ PROMETHAZINE HYDROCHLORIDE On Formulary >3.4.1 Antihistamines‐>Sedating antihistamines

PROMETHAZINE HYDROCHLORIDE On Formulary 4.1 Hypnotics and anxiolytics‐>4.1.1 Hypnotics‐>Antihistamines PROMETHAZINE HYDROCHLORIDE On Formulary 4.6 Drugs used in nausea and vertigo‐>Antihistamines

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

1.2 Antispasmodics and other drugs altering gut motility‐ PROPANTHELINE BROMIDE On Formulary >Antimuscarinics

7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary PROPANTHELINE BROMIDE On Formulary frequency, enuresis, and incontinence‐>Urinary incontinence

7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics‐ Royal Free Maternity Unit Guideline PropessÂ® On Formulary >DINOPROSTONE for Induction of Labour

7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary PROPIVERINE HYDROCHLORIDE On Formulary frequency, enuresis, and incontinence‐>Urinary incontinence 15.1 General anaesthesia‐>15.1.1 Intravenous anaesthetics‐>Drugs PROPOFOL On Formulary used for intravenous anaesthesia

15.1 General anaesthesia‐>15.1.1 Intravenous anaesthetics‐>Drugs Propofol On Formulary used for intravenous anaesthesia‐>PROPOFOL Status Epilepticus 2.4 Beta‐adrenoceptor blocking drugs‐>PROPRANOLOL Propranolol On Formulary HYDROCHLORIDE PROPRANOLOL HYDROCHLORIDE On Formulary 2.4 Beta‐adrenoceptor blocking drugs PROPYLTHIOURACIL On Formulary 6.2 Thyroid and antithyroid drugs‐>6.2.2 Antithyroid drugs 6.2 Thyroid and antithyroid drugs‐>6.2.2 Antithyroid drugs‐ Propylthiouracil On Formulary >PROPYLTHIOURACIL

6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists‐>Anti‐ ProscarÂ® On Formulary androgens‐>Dutasteride and finasteride‐>FINASTERIDE

Royal Free Maternity Unit Guideline Prostaglandins and oxytocics On Formulary 7.1 Drugs used in obstetrics on Massive Obstetric Haemorrhage

Only Intravenous solution and Vaginal Gel are kept at the Royal Free 7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics‐ Hospital Royal Free Maternity Unit Prostin E2Â® On Formulary >DINOPROSTONE Guideline for Induction of Labour Protocol for Reversal of UFH and Protamine sulfate On Formulary 2.8 Anticoagulants and protamine LMWH anticoagulation Protocol for Reversal of UFH and PROTAMINE SULFATE On Formulary 2.8 Anticoagulants and protamine‐>2.8.3 Protamine sulfate LMWH anticoagulation 2.8 Anticoagulants and protamine‐>2.8.3 Protamine sulfate‐ Protocol for Reversal of UFH and Protamine Sulfate On Formulary >PROTAMINE SULFATE LMWH anticoagulation

4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant ProthiadenÂ® On Formulary drugs‐>Tricyclic antidepressants‐>DOSULEPIN HYDROCHLORIDE 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.2 Progestogens and progesterone receptor modulators‐ ProveraÂ® On Formulary >MEDROXYPROGESTERONE ACETATE

8.3 Sex hormones and hormone antagonists in malignant disease‐ ProveraÂ® On Formulary >8.3.2 Progestogens‐>MEDROXYPROGESTERONE ACETATE PROXYMETACAINE HYDROCHLORIDE On Formulary 11.7 Local anaesthetics 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake ProzacÂ® On Formulary inhibitors‐>FLUOXETINE PSEUDOEPHEDRINE HYDROCHLORIDE On Formulary 3.10 Systemic nasal decongestants PulmicortÂ® On Formulary 3.2 Corticosteroids‐>BUDESONIDE

Puri‐NetholÂ® On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites‐>MERCAPTOPURINE 1.3 Antisecretory drugs and mucosal protectants‐>Helicobacter pylori PylobactellÂ® On Formulary infection‐>Test for Helicobacter pylori

10.2 Drugs used in neuromuscular disorders‐>10.2.1 Drugs that PYRIDOSTIGMINE BROMIDE On Formulary enhance neuromuscular transmission‐>Anticholinesterases Only the 50mg tablets kept at the Pyridoxine On Formulary 9.6 Vitamins‐>9.6.2 Vitamin B group‐>PYRIDOXINE HYDROCHLORIDE RFH. PYRIDOXINE HYDROCHLORIDE On Formulary 9.6 Vitamins‐>9.6.2 Vitamin B group

PYRIMETHAMINE On Formulary 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Pyrimethamine

PYRIMETHAMINE WITH SULFADOXINE On Formulary 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Pyrimethamine 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Pyrimethamine‐ Pyrimethamine with sulfadoxine On Formulary >PYRIMETHAMINE WITH SULFADOXINE

Questran LightÂ® On Formulary 2.12 Lipid‐regulating drugs‐>Bile acid sequestrants‐>COLESTYRAMINE

QuestranÂ® On Formulary 2.12 Lipid‐regulating drugs‐>Bile acid sequestrants‐>COLESTYRAMINE QUININE On Formulary 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Quinine

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

10.2 Drugs used in neuromuscular disorders‐>10.2.2 Skeletal muscle The 300mg tablet only kept at the QUININE On Formulary relaxants‐>Nocturnal leg cramps RFH

Quinine Dihydrochloride On Formulary 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Quinine‐>QUININE

Quinine Sulfate On Formulary 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Quinine‐>QUININE QvarÂ® On Formulary 3.2 Corticosteroids‐>BECLOMETASONE DIPROPIONATE

14.5 Immunoglobulins‐>14.5.2 Disease‐specific immunoglobulins‐ Not available through pharmacy ‐ Rabies Immunoglobulin On Formulary >Rabies‐>RABIES IMMUNOGLOBULIN obtain from the blood bank.

Rabies Vaccine On Formulary 14.4 Vaccines and antisera‐>Rabies vaccine‐>RABIES VACCINE

RabipurÂ® On Formulary 14.4 Vaccines and antisera‐>Rabies vaccine‐>RABIES VACCINE 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ RALOXIFENE HYDROCHLORIDE On Formulary >6.4.1.1 Oestrogens and HRT‐>Raloxifene RALTITREXED On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme RAMIPRIL On Formulary inhibitors 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme Ramipril On Formulary inhibitors‐>RAMIPRIL 1.3 Antisecretory drugs and mucosal protectants‐>1.3.1 H2‐receptor RANITIDINE On Formulary antagonists 1.3 Antisecretory drugs and mucosal protectants‐>1.3.1 H2‐receptor Ranitidine On Formulary antagonists‐>RANITIDINE

8.2 Drugs affecting the immune response‐>8.2.2 Corticosteroids and RapamuneÂ® On Formulary other immunosuppressants‐>SIROLIMUS

15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ RapifenÂ® On Formulary operative drugs‐>15.1.4.3 Opioid analgesics‐>ALFENTANIL Controlled Drug Requirements 11.4 Corticosteroids and other anti‐inflammatory preparations‐ >11.4.2 Other anti‐inflammatory preparations‐>NEDOCROMIL RapitilÂ® On Formulary SODIUM

REBOXETINE On Formulary 4.3 Antidepressant drugs‐>4.3.4 Other antidepressant drugs 9.8 Metabolic disorders‐>9.8.1 Drugs used in metabolic disorders‐ ReplagalÂ® On Formulary >Fabry's disease‐>AGALSIDASE ALFA and BETA 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor RequipÂ® On Formulary agonists‐>ROPINIROLE

RescueFlow bags are not kept at RFH. The following are available at RFH (i) 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid Dextran 70 6% and Sodium chloride and electrolyte imbalance‐>9.2.2.2 Plasma and plasma substitutes‐ 0.9% 500ml bags and (ii) Dextran 70 RescueFlowÂ® On Formulary >Plasma substitutes‐>DEXTRAN 70‐>Hypertonic solution 6% and Glucose 5% 500ml bags.

9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and electrolyte imbalance‐>9.2.1.1 Oral potassium‐>Management of Resonium AÂ® On Formulary hyperkalaemia‐>POLYSTYRENE SULFONATE RESINS

ResourceÂ® Thickened Drink On Formulary A2.5 Feed additives‐>A2.5.2 Feed thickeners and pre‐thickened drinks

ResourceÂ® ThickenUpÂ® On Formulary A2.5 Feed additives‐>A2.5.2 Feed thickeners and pre‐thickened drinks 3.1 Bronchodilators‐>3.1.2 Antimuscarinic bronchodilators‐ RespontinÂ® On Formulary >IPRATROPIUM BROMIDE 6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists‐ RestandolÂ® Testocaps On Formulary >TESTOSTERONE AND ESTERS‐>Oral 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse RetrovirÂ® On Formulary transcriptase inhibitors‐>ZIDOVUDINE As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors‐ ReyatazÂ® On Formulary >ATAZANAVIR As per HIV guidelines. 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ Rhinocort AquaÂ® On Formulary >Corticosteroids‐>BUDESONIDE Available at the RNTNE only. 5.4 Antiprotozoal drugs‐>5.4.1 Antimalarials‐>Artemether with RiametÂ® On Formulary lumefantrine‐>ARTEMETHER WITH LUMEFANTRINE 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs‐>RIFAMPICIN‐ RifaterÂ® On Formulary >Combined preparations 12.2 Drugs acting on the nose‐>12.2.2 Topical nasal decongestants‐ RinatecÂ® On Formulary >Antimuscarinic‐>IPRATROPIUM BROMIDE

6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and RISEDRONATE SODIUM On Formulary other drugs affecting bone metabolism‐>Bisphosphonates

RITONAVIR On Formulary 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors As per HIV guidelines. RIVASTIGMINE On Formulary 4.11 Dementia

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

13.6 Acne and rosacea‐>13.6.2 Oral preparations for acne‐>Oral RoaccutaneÂ® On Formulary retinoid for acne‐>ISOTRETINOIN

10.2 Drugs used in neuromuscular disorders‐>10.2.2 Skeletal muscle RobaxinÂ® On Formulary relaxants‐>Other muscle relaxants‐>METHOCARBAMOL RocaltrolÂ® On Formulary 9.6 Vitamins‐>9.6.4 Vitamin D‐>CALCITRIOL

15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ ROCURONIUM BROMIDE On Formulary >Non‐depolarising neuromuscular blocking drugs

IntronA is the preferred brand of 8.2 Drugs affecting the immune response‐>8.2.4 Other interferon alfa for haematology Roferon‐AÂ® On Formulary immunomodulating drugs‐>Interferon alfa‐>INTERFERON ALFA & oncology patients 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor Only the Requip® brand is kept at ROPINIROLE On Formulary agonists the RFH. 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ RynacromÂ® On Formulary >Cromoglicate‐>SODIUM CROMOGLICATE 2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ >Supraventricular and ventricular arrhythmias‐>DISOPYRAMIDE‐ Rythmodan RetardÂ® On Formulary >Modified release

2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ RythmodanÂ® On Formulary >Supraventricular and ventricular arrhythmias‐>DISOPYRAMIDE 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Vigabatrin‐ SabrilÂ® On Formulary >VIGABATRIN SalactolÂ® On Formulary 13.7 Preparations for warts and calluses‐>SALICYLIC ACID

12.3 Drugs acting on the oropharynx‐>12.3.5 Treatment of dry mouth‐ SalagenÂ® On Formulary >Systemic treatment‐>PILOCARPINE HYDROCHLORIDE

3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective Salamol Easi‐BreatheÂ® On Formulary beta2 agonists‐>SALBUTAMOL‐>Inhalation 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Sulfasalazine‐ Salazopyrin EN‐TabsÂ® On Formulary >SULFASALAZINE

SalazopyrinÂ® On Formulary 1.5 Chronic bowel disorders‐>1.5.1 Aminosalicylates‐>SULFASALAZINE

3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective Salbulin NovolizerÂ® On Formulary beta2 agonists‐>SALBUTAMOL‐>Inhalation 3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective SALBUTAMOL On Formulary beta2 agonists 3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective Salbutamol On Formulary beta2 agonists‐>SALBUTAMOL‐>Oral

3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective Administration of drugs via inhalers Salbutamol On Formulary beta2 agonists‐>SALBUTAMOL‐>Inhalation guideline 12.3 Drugs acting on the oropharynx‐>12.3.1 Drugs for oral ulceration SALICYLATES On Formulary and inflammation

13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for SALICYLIC ACID On Formulary psoriasis‐>Topical preparations for psoriasis‐>Salicylic acid SALICYLIC ACID On Formulary 13.7 Preparations for warts and calluses 3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective SALMETEROL On Formulary beta2 agonists

SalofalkÂ® On Formulary 1.5 Chronic bowel disorders‐>1.5.1 Aminosalicylates‐>MESALAZINE

8.2 Drugs affecting the immune response‐>8.2.2 Corticosteroids and SandimmunÂ® On Formulary other immunosuppressants‐>CICLOSPORIN 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and electrolyte imbalance‐>9.2.1.1 Oral potassium‐>POTASSIUM Sando‐KÂ® On Formulary CHLORIDE 9.5 Minerals‐>9.5.1 Calcium and magnesium‐>9.5.1.1 Calcium SandocalÂ® On Formulary supplements‐>CALCIUM SALTS‐>Oral preparations 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.3 Somatostatin analogues‐ SandostatinÂ® On Formulary >OCTREOTIDE

4.7 Analgesics‐>4.7.4 Antimigraine drugs‐>4.7.4.2 Prophylaxis of The pizotifen elixir is not available at SanomigranÂ® On Formulary migraine‐>PIZOTIFEN The Royal Free Hospital.

SAQUINAVIR On Formulary 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors As per HIV guidelines.

1.7 Local preparations for anal and rectal disorders‐>1.7.2 Compound ScheriproctÂ® On Formulary haemorrhoidal preparations with corticosteroids 4.6 Drugs used in nausea and vertigo‐>Hyoscine‐>HYOSCINE Scopoderm TTSÂ® On Formulary HYDROBROMIDE‐>Patches

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Tars‐>TARS‐ SebcoÂ® On Formulary >Proprietary preparations 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.2 Calcium‐channel blockers‐>VERAPAMIL HYDROCHLORIDE‐ Securon SRÂ® On Formulary >Modified release 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Monoamine‐ SELEGILINE HYDROCHLORIDE On Formulary oxidase‐B inhibitors

4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Monoamine‐ Selegiline Hydrochloride On Formulary oxidase‐B inhibitors‐>SELEGILINE HYDROCHLORIDE 10mg tablets are not kept at the RFH. 13.9 Shampoos and other preparations for scalp and hair conditions‐ SelsunÂ® On Formulary >Shampoos SENNA On Formulary 1.6 Laxatives‐>1.6.2 Stimulant laxatives Senna On Formulary 1.6 Laxatives‐>1.6.2 Stimulant laxatives‐>SENNA Only tablets and liquid kept at the SenokotÂ® On Formulary 1.6 Laxatives‐>1.6.2 Stimulant laxatives‐>SENNA RFH 4.6 Drugs used in nausea and vertigo‐>Other drugs for MÃ©niÃ¨re's SercÂ® On Formulary disease‐>BETAHISTINE DIHYDROCHLORIDE 3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective Administration of drugs via inhalers SereventÂ® On Formulary beta2 agonists‐>SALMETEROL guideline 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake SeroxatÂ® On Formulary inhibitors‐>PAROXETINE 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake SERTRALINE On Formulary inhibitors 4.3 Antidepressant drugs‐>4.3.3 Selective serotonin re‐uptake Sertraline On Formulary inhibitors‐>SERTRALINE 15.1 General anaesthesia‐>15.1.2 Inhalational anaesthetics‐>Volatile SEVOFLURANE On Formulary liquid anaesthetics

SevredolÂ® On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>MORPHINE SALTS‐>Tablets North London Cancer Network Side‐effects of cytotoxic drugs On Formulary 8.1 Cytotoxic drugs Antiemetic Policy 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Vitamin D and SilkisÂ® On Formulary analogues‐>CALCITRIOL SILVER NITRATE On Formulary 13.7 Preparations for warts and calluses 13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial preparations‐>13.10.1.1 Antibacterial preparations only used SILVER SULFADIAZINE On Formulary topically

11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, Simple Eye Ointment On Formulary ocular lubricants, and astringents‐>PARAFFIN, YELLOW, SOFT 3.9 Cough preparations‐>3.9.2 Demulcent and expectorant cough Simple Linctus, BP On Formulary preparations SIMVASTATIN On Formulary 2.12 Lipid‐regulating drugs‐>Statins Simvastatin On Formulary 2.12 Lipid‐regulating drugs‐>Statins‐>SIMVASTATIN 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Levodopa‐>CO‐ Sinemet 62.5/5ml and 110/5ml SinemetÂ® On Formulary CARELDOPA suspensions are also kept at the RFH. 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Levodopa‐>CO‐ SinemetÂ® CR On Formulary CARELDOPA‐>Modified release 8.2 Drugs affecting the immune response‐>8.2.2 Corticosteroids and SIROLIMUS On Formulary other immunosuppressants Skeletal muscle relaxants On Formulary 10.2 Drugs used in neuromuscular disorders Motor neurone disease policy 13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐ SkinorenÂ® On Formulary >Benzoyl peroxide and azelaic acid‐>AZELAIC ACID 3.1 Bronchodilators‐>3.1.3 Theophylline‐>THEOPHYLLINE‐>Modified Slo‐PhyllinÂ® On Formulary release 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and electrolyte imbalance‐>9.2.1.1 Oral potassium‐>POTASSIUM Slow‐KÂ® On Formulary CHLORIDE‐>Modified‐release preparations 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and electrolyte imbalance‐>9.2.1.2 Oral sodium and water‐>SODIUM Slow SodiumÂ® On Formulary CHLORIDE 8.1 Cytotoxic drugs‐>Treatment for cytotoxic‐induced side‐effects‐ >Chemotherapy‐induced mucositis and myelosuppression‐>FOLINIC SodiofolinÂ® On Formulary ACID‐>Disodium folinate 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that SODIUM AUROTHIOMALATE On Formulary suppress the rheumatic disease process‐>Gold 7.4 Drugs for genito‐urinary disorders‐>7.4.3 Drugs used in urological SODIUM BICARBONATE On Formulary pain‐>Alkalinisation of urine 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and SODIUM BICARBONATE On Formulary electrolyte imbalance‐>9.2.1.3 Oral bicarbonate 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and electrolyte imbalance‐>9.2.1.3 Oral bicarbonate‐>SODIUM Only 500mg capsules are available at Sodium Bicarbonate On Formulary BICARBONATE RFH.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ SODIUM BICARBONATE On Formulary >Bicarbonate and lactate Sodium Bicarbonate On Formulary 12.1 Drugs acting on the ear‐>12.1.3 Removal of earwax

9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ Sodium Bicarbonate Intravenous Infusion On Formulary >Bicarbonate and lactate‐>SODIUM BICARBONATE 3.1 Bronchodilators‐>3.1.5 Peak flow meters, inhaler devices and Sodium Chloride On Formulary nebulisers‐>Nebuliser diluent

9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and SODIUM CHLORIDE On Formulary electrolyte imbalance‐>9.2.1.2 Oral sodium and water 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ SODIUM CHLORIDE On Formulary >Intravenous sodium 11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, SODIUM CHLORIDE On Formulary ocular lubricants, and astringents 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.1 SODIUM CHLORIDE On Formulary Alcohols and saline 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.1 Sodium Chloride On Formulary Alcohols and saline‐>SODIUM CHLORIDE

7.4 Drugs for genito‐urinary disorders‐>7.4.4 Bladder instillations and urological surgery‐>Maintenance of indwelling urinary catheters‐ Only Sodium Chloride Uro‐Tainer M Sodium chloride 0.9% On Formulary >CATHETER PATENCY SOLUTIONS kept at the RFH

9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid Sodium Chloride and Glucose Intravenous and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ Infusion On Formulary >Intravenous sodium‐>SODIUM CHLORIDE‐>With other ingredients 9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ Sodium Chloride Intravenous Infusion On Formulary >Intravenous sodium‐>SODIUM CHLORIDE SODIUM CITRATE (RECTAL) On Formulary 1.6 Laxatives‐>1.6.4 Osmotic laxatives

6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and SODIUM CLODRONATE On Formulary other drugs affecting bone metabolism‐>Bisphosphonates 3.3 Cromoglicate and related therapy, leukotriene receptor antagonists, and phosphodiesterase type‐4 inhibitors‐>3.3.1 SODIUM CROMOGLICATE On Formulary Cromoglicate and related therapy Only available at the RNTNE.

11.4 Corticosteroids and other anti‐inflammatory preparations‐ SODIUM CROMOGLICATE On Formulary >11.4.2 Other anti‐inflammatory preparations 11.4 Corticosteroids and other anti‐inflammatory preparations‐ >11.4.2 Other anti‐inflammatory preparations‐>SODIUM Sodium Cromoglicate On Formulary CROMOGLICATE 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ SODIUM CROMOGLICATE On Formulary >Cromoglicate 9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency SODIUM FEREDETATE On Formulary anaemias‐>9.1.1.1 Oral iron

SODIUM FUSIDATE On Formulary 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐>Fusidic acid

9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid Sodium Lactate Intravenous Infusion, and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐ Compound On Formulary >Intravenous sodium‐>SODIUM CHLORIDE‐>With other ingredients SODIUM NITRITE On Formulary Other poisons‐>Cyanides Sodium Nitrite On Formulary Other poisons‐>Cyanides‐>SODIUM NITRITE 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator SODIUM NITROPRUSSIDE On Formulary antihypertensive drugs 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator Sodium Nitroprusside On Formulary antihypertensive drugs‐>SODIUM NITROPRUSSIDE SODIUM PICOSULFATE On Formulary 1.6 Laxatives‐>1.6.2 Stimulant laxatives

Sodium Picosulfate On Formulary 1.6 Laxatives‐>1.6.2 Stimulant laxatives‐>SODIUM PICOSULFATE SODIUM TETRADECYL SULFATE On Formulary 2.13 Local sclerosants SODIUM THIOSULFATE On Formulary Other poisons‐>Cyanides Sodium Thiosulfate On Formulary Other poisons‐>Cyanides‐>SODIUM THIOSULFATE

SODIUM VALPROATE On Formulary 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Valproate 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Valproate‐ Sodium Valproate On Formulary >SODIUM VALPROATE‐>Oral

11.4 Corticosteroids and other anti‐inflammatory preparations‐ SofradexÂ® On Formulary >11.4.1 Corticosteroids‐>DEXAMETHASONE‐>With antibacterials 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ inflammatory preparations‐>Corticosteroids‐>DEXAMETHASONE‐ SofradexÂ® On Formulary >With antibacterial

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐infective SofradexÂ® On Formulary preparations‐>FRAMYCETIN SULFATE‐>With corticosteroid Solivito NÂ® On Formulary 9.3 Intravenous nutrition‐>Supplementary preparations 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy‐ Solu‐CortefÂ® On Formulary >HYDROCORTISONE 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy‐ Solu‐MedroneÂ® On Formulary >METHYLPREDNISOLONE Zinc Sulphate 220mg capsules also SolvazincÂ® On Formulary 9.5 Minerals‐>9.5.4 Zinc‐>ZINC SULFATE kept at the RFH.

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ SOMATROPIN On Formulary >Anterior pituitary hormones‐>Growth hormone

SotacorÂ® On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>SOTALOL HYDROCHLORIDE Sotalol injection not kept at the RFH.

Sotalol On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>SOTALOL HYDROCHLORIDE Sotalol injection not kept at the RFH.

SOTALOL HYDROCHLORIDE On Formulary 2.4 Beta‐adrenoceptor blocking drugs Sotalol injection not kept at the RFH.

3.1 Bronchodilators‐>3.1.2 Antimuscarinic bronchodilators‐ Respimat® is non‐formulary and SpirivaÂ® On Formulary >TIOTROPIUM is not available at RFH. 2.2 Diuretics‐>2.2.3 Potassium‐sparing diuretics and aldosterone SPIRONOLACTONE On Formulary antagonists‐>Aldosterone antagonists

2.2 Diuretics‐>2.2.3 Potassium‐sparing diuretics and aldosterone Spironolactone On Formulary antagonists‐>Aldosterone antagonists‐>SPIRONOLACTONE 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Levodopa‐>CO‐ StalevoÂ® On Formulary CARELDOPA‐>With entacapone 3.1 Bronchodilators‐>3.1.5 Peak flow meters, inhaler devices and Standard Range Peak Flow Meter On Formulary nebulisers‐>Peak flow meters 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other StarlixÂ® On Formulary antidiabetic drugs‐>NATEGLINIDE 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse STAVUDINE On Formulary transcriptase inhibitors As per HIV guidelines. 4.6 Drugs used in nausea and vertigo‐>Phenothiazines and related StemetilÂ® On Formulary drugs‐>PROCHLORPERAZINE SteripasteÂ® On Formulary A5.8 Bandages‐>A5.8.9 Medicated bandages

Stoma care ‐ guidelines for nurses Stoma care On Formulary caring for patients with a stoma STREPTOMYCIN On Formulary 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs‐ Streptomycin Sulfate On Formulary >STREPTOMYCIN

StugeronÂ® On Formulary 4.6 Drugs used in nausea and vertigo‐>Antihistamines‐>CINNARIZINE

15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ SublimazeÂ® On Formulary operative drugs‐>15.1.4.3 Opioid analgesics‐>FENTANYL Controlled Drug Requirements

4.10 Drugs used in substance dependence‐>4.10.3 Opioid 400mcg tablets not kept at the RFH. SubutexÂ® On Formulary dependence‐>Opioid substitution therapy‐>BUPRENORPHINE Managing opiate addiction 1.3 Antisecretory drugs and mucosal protectants‐>1.3.3 Chelates and SUCRALFATE On Formulary complexes 3.10 Systemic nasal decongestants‐>PSEUDOEPHEDRINE SudafedÂ® On Formulary HYDROCHLORIDE 13.2 Emollient and barrier preparations‐>13.2.2 Barrier preparations‐ SudocremÂ® On Formulary >Proprietary barrier preparations SULFASALAZINE On Formulary 1.5 Chronic bowel disorders‐>1.5.1 Aminosalicylates

Sulfasalazine On Formulary 1.5 Chronic bowel disorders‐>1.5.1 Aminosalicylates‐>SULFASALAZINE

10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that SULFASALAZINE On Formulary suppress the rheumatic disease process‐>Sulfasalazine 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Sulfasalazine‐ Sulfasalazine On Formulary >SULFASALAZINE

10.1 Drugs used in rheumatic diseases and gout‐>10.1.4 Gout and SULFINPYRAZONE On Formulary cytotoxic‐induced hyperuricaemia‐>Long‐term control of gout 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ SULINDAC On Formulary steroidal anti‐inflammatory drugs 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Sulindac On Formulary steroidal anti‐inflammatory drugs‐>SULINDAC

SunsenseÂ® Ultra On Formulary 13.8 Sunscreens and camouflagers‐>13.8.1 Sunscreen preparations

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant SurmontilÂ® On Formulary drugs‐>Tricyclic antidepressants‐>TRIMIPRAMINE 6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists‐ Sustanon 250Â® On Formulary >TESTOSTERONE AND ESTERS‐>Intramuscular 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Non‐nucleoside reverse SustivaÂ® On Formulary transcriptase inhibitors‐>EFAVIRENZ As per HIV guidelines.

15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ SUXAMETHONIUM CHLORIDE On Formulary >Depolarising neuromuscular blocking drugs 15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ >Depolarising neuromuscular blocking drugs‐>SUXAMETHONIUM Suxamethonium Chloride On Formulary CHLORIDE

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ Synacthen DepotÂ® On Formulary >Anterior pituitary hormones‐>Corticotrophins‐>TETRACOSACTIDE

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ SynacthenÂ® On Formulary >Anterior pituitary hormones‐>Corticotrophins‐>TETRACOSACTIDE Synalar 1 in 10 DilutionÂ® On Formulary 13.4 Topical corticosteroids‐>FLUOCINOLONE ACETONIDE Only Cream available at the Royal Synalar 1 in 4 DilutionÂ® On Formulary 13.4 Topical corticosteroids‐>FLUOCINOLONE ACETONIDE Free Hospital. SynalarÂ® On Formulary 13.4 Topical corticosteroids‐>FLUOCINOLONE ACETONIDE 6.7 Other endocrine drugs‐>6.7.2 Drugs affecting gonadotrophins‐ SynarelÂ® On Formulary >Gonadorelin analogues‐>NAFARELIN

7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics‐ Royal Free Maternity Unit Guideline SyntocinonÂ® On Formulary >OXYTOCIN for Massive Obstetric Haemorrhage 7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics‐ SyntometrineÂ® On Formulary >ERGOMETRINE MALEATE‐>With oxytocin

9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency SytronÂ® On Formulary anaemias‐>9.1.1.1 Oral iron‐>SODIUM FEREDETATE 8.2 Drugs affecting the immune response‐>8.2.2 Corticosteroids and TACROLIMUS On Formulary other immunosuppressants

2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ TambocorÂ® On Formulary >Supraventricular and ventricular arrhythmias‐>FLECAINIDE ACETATE

8.3 Sex hormones and hormone antagonists in malignant disease‐ TAMOXIFEN On Formulary >8.3.4 Hormone antagonists‐>8.3.4.1 Breast cancer

8.3 Sex hormones and hormone antagonists in malignant disease‐ Tamoxifen On Formulary >8.3.4 Hormone antagonists‐>8.3.4.1 Breast cancer‐>TAMOXIFEN 7.4 Drugs for genito‐urinary disorders‐>7.4.1 Drugs for urinary TAMSULOSIN HYDROCHLORIDE On Formulary retention‐>Alpha‐blockers

7.4 Drugs for genito‐urinary disorders‐>7.4.1 Drugs for urinary Tamsulosin hydrochloride On Formulary retention‐>Alpha‐blockers‐>TAMSULOSIN HYDROCHLORIDE

13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for TARS On Formulary psoriasis‐>Topical preparations for psoriasis‐>Tars See individual drugs for specific Taxanes On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs indications for use

13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for TAZAROTENE On Formulary psoriasis‐>Topical preparations for psoriasis‐>Tazarotene

5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.4 Antipseudomonal TazocinÂ® On Formulary penicillins‐>PIPERACILLIN WITH TAZOBACTAM

4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ TegretolÂ® On Formulary >Carbamazepine and related antiepileptics‐>CARBAMAZEPINE 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ >Carbamazepine and related antiepileptics‐>CARBAMAZEPINE‐ TegretolÂ® Prolonged Release On Formulary >Modified release 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors‐ TelzirÂ® On Formulary >FOSAMPRENAVIR As per HIV guidelines.

TEMAZEPAM On Formulary 4.1 Hypnotics and anxiolytics‐>4.1.1 Hypnotics‐>Benzodiazepines 4.1 Hypnotics and anxiolytics‐>4.1.1 Hypnotics‐>Benzodiazepines‐ Temazepam On Formulary >TEMAZEPAM 15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ TEMAZEPAM On Formulary operative drugs‐>15.1.4.1 Benzodiazepines TemgesicÂ® On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>BUPRENORPHINE Managing opiate addiction 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse TENOFOVIR DISOPROXIL On Formulary transcriptase inhibitors As per HIV guidelines. Tenoret 50Â® On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>CO‐TENIDONE

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

TenoreticÂ® On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>CO‐TENIDONE Atenolol injection restricted to TenorminÂ® On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>ATENOLOL cardiology and ITU only. 11.6 Treatment of glaucoma‐>Beta‐blockers‐>CARTEOLOL TeopticÂ® On Formulary HYDROCHLORIDE TERBINAFINE On Formulary 5.2 Antifungal drugs‐>5.2.5 Other antifungals

Terbinafine On Formulary 5.2 Antifungal drugs‐>5.2.5 Other antifungals‐>TERBINAFINE 3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective TERBUTALINE SULFATE On Formulary beta2 agonists 6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.2 Posterior pituitary hormones and antagonists‐>Posterior pituitary TERLIPRESSIN ACETATE On Formulary hormones

TESTOSTERONE AND ESTERS On Formulary 6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists 6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists‐ Testosterone Enantate On Formulary >TESTOSTERONE AND ESTERS‐>Intramuscular 14.5 Immunoglobulins‐>14.5.2 Disease‐specific immunoglobulins‐ Not available through Pharmacy. Tetanus Immunoglobulin On Formulary >Tetanus‐>TETANUS IMMUNOGLOBULIN Obtain from BPL.

4.9 Drugs used in parkinsonism and related disorders‐>4.9.3 Drugs TETRABENAZINE On Formulary used in essential tremor, chorea, tics, and related disorders TETRACAINE On Formulary 15.2 Local anaesthesia‐>Tetracaine TETRACAINE HYDROCHLORIDE On Formulary 11.7 Local anaesthetics

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ TETRACOSACTIDE On Formulary >Anterior pituitary hormones‐>Corticotrophins TETRACYCLINE On Formulary 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines

Tetracycline On Formulary 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines‐>TETRACYCLINE Tetralysal 300Â® On Formulary 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines‐>LYMECYCLINE 8.2 Drugs affecting the immune response‐>8.2.4 Other immunomodulating drugs‐>Lenalidomide, pomalidomide, and THALIDOMIDE On Formulary thalidomide THEOPHYLLINE On Formulary 3.1 Bronchodilators‐>3.1.3 Theophylline THIAMINE On Formulary 9.6 Vitamins‐>9.6.2 Vitamin B group Thiamine On Formulary 9.6 Vitamins‐>9.6.2 Vitamin B group‐>THIAMINE

15.1 General anaesthesia‐>15.1.1 Intravenous anaesthetics‐>Drugs Thiopental On Formulary used for intravenous anaesthesia‐>THIOPENTAL SODIUM Status Epilepticus 15.1 General anaesthesia‐>15.1.1 Intravenous anaesthetics‐>Drugs THIOPENTAL SODIUM On Formulary used for intravenous anaesthesia THIOTEPA On Formulary 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs

Thixo‐DÂ® On Formulary A2.5 Feed additives‐>A2.5.2 Feed thickeners and pre‐thickened drinks

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ ThyrogenÂ® On Formulary >Anterior pituitary hormones‐>Thyrotrophin‐>THYROTROPIN ALFA

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ THYROTROPIN ALFA On Formulary >Anterior pituitary hormones‐>Thyrotrophin

TIAGABINE On Formulary 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Tiagabine 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.2 Calcium‐channel blockers‐>DILTIAZEM HYDROCHLORIDE‐ Tildiem LAÂ® On Formulary >Longer‐acting formulations 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.2 Calcium‐channel blockers‐>DILTIAZEM HYDROCHLORIDE‐ Tildiem RetardÂ® On Formulary >Longer‐acting formulations 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.2 Calcium‐channel blockers‐>DILTIAZEM HYDROCHLORIDE‐ TildiemÂ® On Formulary >Standard formulations

TimodineÂ® On Formulary 13.4 Topical corticosteroids‐>HYDROCORTISONE‐>With antimicrobials TIMOLOL On Formulary 11.6 Treatment of glaucoma‐>Beta‐blockers Timolol On Formulary 11.6 Treatment of glaucoma‐>Beta‐blockers‐>TIMOLOL Unit dose eye drops are not kept at TimoptolÂ® On Formulary 11.6 Treatment of glaucoma‐>Beta‐blockers‐>TIMOLOL RFH. 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ Low molecular weight heparin TINZAPARIN SODIUM On Formulary >Low molecular weight heparins protocol 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal TIOCONAZOLE On Formulary preparations TIOGUANINE On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites

TIOTROPIUM On Formulary 3.1 Bronchodilators‐>3.1.2 Antimuscarinic bronchodilators

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.2 TiseptÂ® On Formulary Chlorhexidine salts‐>CHLORHEXIDINE‐>With cetrimide 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.1 TOLBUTAMIDE On Formulary Sulfonylureas 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.1 Tolbutamide On Formulary Sulfonylureas‐>TOLBUTAMIDE

7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary TOLTERODINE TARTRATE On Formulary frequency, enuresis, and incontinence‐>Urinary incontinence 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Topiramate‐ 50mg and 200mg tablets are not kept TopamaxÂ® On Formulary >TOPIRAMATE at the RFH.

TOPIRAMATE On Formulary 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Topiramate Topoisomerase I inhibitors On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs 15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ >Non‐depolarising neuromuscular blocking drugs‐>ATRACURIUM TracriumÂ® On Formulary BESILATE 7.1 Drugs used in obstetrics‐>7.1.3 Myometrial relaxants‐>Atosiban‐ Royal Free Maternity Unit Guideline TractocileÂ® On Formulary >ATOSIBAN for Pre‐Term labour TRAMADOL HYDROCHLORIDE On Formulary 4.7 Analgesics‐>4.7.2 Opioid analgesics 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>TRAMADOL Tramadol Hydrochloride On Formulary HYDROCHLORIDE

TrandateÂ® On Formulary 2.4 Beta‐adrenoceptor blocking drugs‐>LABETALOL HYDROCHLORIDE TRANEXAMIC ACID On Formulary 2.11 Antifibrinolytic drugs and haemostatics

Tranexamic acid On Formulary 2.11 Antifibrinolytic drugs and haemostatics‐>TRANEXAMIC ACID

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Transiderm‐NitroÂ® On Formulary >2.6.1 Nitrates‐>GLYCERYL TRINITRATE‐>Transdermal preparations

TRANYLCYPROMINE On Formulary 4.3 Antidepressant drugs‐>4.3.2 Monoamine‐oxidase inhibitors 4.3 Antidepressant drugs‐>4.3.2 Monoamine‐oxidase inhibitors‐ Tranylcypromine On Formulary >TRANYLCYPROMINE 11.6 Treatment of glaucoma‐>Prostaglandin analogues and TRAVOPROST On Formulary prostamides Treatment of hypoglycaemia On Formulary 6.1 Drugs used in diabetes Hypoglycaemia protocol

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ TrentalÂ® On Formulary >2.6.4 Peripheral vasodilators and related drugs‐>PENTOXIFYLLINE Tretinoin On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs

TRETINOIN On Formulary 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Tretinoin TRIAMCINOLONE On Formulary 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ TRIAMCINOLONE ACETONIDE On Formulary >Corticosteroids TRIAMCINOLONE ACETONIDE On Formulary 13.4 Topical corticosteroids 9.8 Metabolic disorders‐>9.8.1 Drugs used in metabolic disorders‐ TRIENTINE DIHYDROCHLORIDE On Formulary >Wilson's disease

9.8 Metabolic disorders‐>9.8.1 Drugs used in metabolic disorders‐ Trientine Dihydrochloride On Formulary >Wilson's disease‐>TRIENTINE DIHYDROCHLORIDE 4.6 Drugs used in nausea and vertigo‐>Phenothiazines and related Stelazine Syrup (1mg/5ml) is not kept TRIFLUOPERAZINE On Formulary drugs at The RFH. 4.9 Drugs used in parkinsonism and related disorders‐>4.9.2 Antimuscarinic drugs used in parkinsonism‐>TRIHEXYPHENIDYL Trihexyphenidyl On Formulary HYDROCHLORIDE 4.9 Drugs used in parkinsonism and related disorders‐>4.9.2 TRIHEXYPHENIDYL HYDROCHLORIDE On Formulary Antimuscarinic drugs used in parkinsonism

TRIMETHOPRIM On Formulary 5.1 Antibacterial drugs‐>5.1.8 Sulfonamides and trimethoprim 5.1 Antibacterial drugs‐>5.1.8 Sulfonamides and trimethoprim‐ Trimethoprim On Formulary >TRIMETHOPRIM 4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant TRIMIPRAMINE On Formulary drugs‐>Tricyclic antidepressants 13.4 Topical corticosteroids‐>CLOBETASONE BUTYRATE‐>With TrimovateÂ® On Formulary antimicrobials 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme TritaceÂ® On Formulary inhibitors‐>RAMIPRIL

5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse TrizivirÂ® On Formulary transcriptase inhibitors‐>ABACAVIR‐>With lamivudine and zidovudine As per HIV guidelines. TROPICAMIDE On Formulary 11.5 Mydriatics and cycloplegics‐>Antimuscarinics 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal TrosylÂ® On Formulary preparations‐>TIOCONAZOLE 11.6 Treatment of glaucoma‐>Carbonic anhydrase inhibitors and TrusoptÂ® On Formulary systemic drugs‐>DORZOLAMIDE

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse transcriptase inhibitors‐>TENOFOVIR DISOPROXIL‐>With TruvadaÂ® On Formulary emtricitabine As per HIV guidelines.

Tuberculin Purified Protein Derivative On Formulary 14.4 Vaccines and antisera‐>BCG vaccines‐>Diagnostic agents 14.4 Vaccines and antisera‐>Hepatitis A vaccine‐>HEPATITIS A Twinrix Paediatric not kept at the TwinrixÂ® On Formulary VACCINE‐>With hepatitis B vaccine RFH. 14.4 Vaccines and antisera‐>Typhoid vaccines‐>TYPHOID VACCINE‐ Typhim ViÂ® On Formulary >Typhoid polysaccharide vaccine for injection 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.1 Antihistamines‐>Sedating antihistamines‐>HYDROXYZINE UceraxÂ® On Formulary HYDROCHLORIDE

Approved for licensed indication only. Full treatment 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ course i.e. up to three >6.4.1.2 Progestogens and progesterone receptor modulators‐ months supply to ULIPRISTAL ACETATE On Formulary >Progesterone receptor modulators be prescribed from Royal Free. 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐ Unguentum MÂ® On Formulary >Proprietary emollient preparations Only 50g tube kept at the RFH. 3.1 Bronchodilators‐>3.1.3 Theophylline‐>THEOPHYLLINE‐>Modified Uniphyllin ContinusÂ® On Formulary release 13.11 Skin cleansers, antiseptics, and desloughing agents‐>13.11.2 UniseptÂ® On Formulary Chlorhexidine salts‐>CHLORHEXIDINE 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.2 Calcium‐channel blockers‐>VERAPAMIL HYDROCHLORIDE‐ UniverÂ® On Formulary >Modified release 7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary frequency, enuresis, and incontinence‐>Urinary incontinence‐ Urispas 200Â® On Formulary >FLAVOXATE HYDROCHLORIDE 1.9 Drugs affecting intestinal secretions‐>1.9.1 Drugs affecting biliary URSODEOXYCHOLIC ACID On Formulary composition and flow

1.9 Drugs affecting intestinal secretions‐>1.9.1 Drugs affecting biliary Ursodeoxycholic Acid On Formulary composition and flow‐>URSODEOXYCHOLIC ACID

1.9 Drugs affecting intestinal secretions‐>1.9.1 Drugs affecting biliary UrsofalkÂ® On Formulary composition and flow‐>URSODEOXYCHOLIC ACID Use of corticosteroids On Formulary 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy Osteoporosis prevention 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.2 Progestogens and progesterone receptor modulators‐ UtovlanÂ® On Formulary >NORETHISTERONE Only Uvistat Cream SPF 30 is kept at UvistatÂ® On Formulary 13.8 Sunscreens and camouflagers‐>13.8.1 Sunscreen preparations The Royal Free Hospital. 7.2 Treatment of vaginal and vulval conditions‐>7.2.1 Preparations for vaginal and vulval changes‐>Topical HRT for vaginal atrophy‐ VagifemÂ® On Formulary >OESTROGENS, TOPICAL

ValoidÂ® On Formulary 4.6 Drugs used in nausea and vertigo‐>Antihistamines‐>CYCLIZINE

2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ VALSARTAN On Formulary angiotensin system‐>2.5.5.2 Angiotensin‐II receptor antagonists 4.10 Drugs used in substance dependence‐>4.10.2 Nicotine VARENICLINE On Formulary dependence‐>Varenicline Not available through pharmacy. Health Protection Agency, NHS 14.5 Immunoglobulins‐>14.5.2 Disease‐specific immunoglobulins‐ laboratories or BPL should be Varicellaâ€“Zoster Immunoglobulin On Formulary >Varicellaâ€“zoster‐>VARICELLAâ€“ZOSTER IMMUNOGLOBULIN contacted. 14.4 Vaccines and antisera‐>Varicellaâ€“zoster vaccines‐>VARICELLA‐ VarilrixÂ® On Formulary ZOSTER VACCINE 6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.2 Posterior pituitary hormones and antagonists‐>Posterior pituitary VASOPRESSIN On Formulary hormones

15.1 General anaesthesia‐>15.1.5 Neuromuscular blocking drugs‐ VECURONIUM BROMIDE On Formulary >Non‐depolarising neuromuscular blocking drugs 8.1 Cytotoxic drugs‐>8.1.4 Vinca alkaloids and etoposide‐ VelbeÂ® On Formulary >VINBLASTINE SULFATE 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase VEMURAFENIB On Formulary inhibitors Approved as per NICE TA 269

VENLAFAXINE On Formulary 4.3 Antidepressant drugs‐>4.3.4 Other antidepressant drugs

9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency VenoferÂ® On Formulary anaemias‐>9.1.1.2 Parenteral iron‐>IRON SUCROSE Renal anaemia 3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective VentolinÂ® On Formulary beta2 agonists‐>SALBUTAMOL‐>Oral

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective VentolinÂ® On Formulary beta2 agonists‐>SALBUTAMOL‐>Parenteral Ventolin Accuhaler® is NON‐ 3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective FORMULARY. Administration of drugs VentolinÂ® On Formulary beta2 agonists‐>SALBUTAMOL‐>Inhalation via inhalers guideline

VepesidÂ® On Formulary 8.1 Cytotoxic drugs‐>8.1.4 Vinca alkaloids and etoposide‐>ETOPOSIDE

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Verapamil On Formulary >2.6.2 Calcium‐channel blockers‐>VERAPAMIL HYDROCHLORIDE 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ VERAPAMIL HYDROCHLORIDE On Formulary >2.6.2 Calcium‐channel blockers 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.2 Calcium‐channel blockers‐>VERAPAMIL HYDROCHLORIDE‐ Verapress MRÂ® On Formulary >Modified release

VermoxÂ® On Formulary 5.5 Anthelmintics‐>5.5.1 Drugs for threadworms‐>MEBENDAZOLE VerrugonÂ® On Formulary 13.7 Preparations for warts and calluses‐>SALICYLIC ACID 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ >2.6.2 Calcium‐channel blockers‐>VERAPAMIL HYDROCHLORIDE‐ VertabÂ® SR 240 On Formulary >Modified release 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Tretinoin‐ VesanoidÂ® On Formulary >TRETINOIN 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse VidexÂ® On Formulary transcriptase inhibitors‐>DIDANOSINE As per HIV guidelines.

VIGABATRIN On Formulary 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Vigabatrin IVIG patient registration form must be completed when initiating IVIG therapy before product can be dispensed. Consult your ward pharmacist for which brand to 14.5 Immunoglobulins‐>14.5.1 Normal immunoglobulin‐>NORMAL prescribe. IVIG patient registration VigamÂ® On Formulary IMMUNOGLOBULIN‐>For intravenous use form 8.1 Cytotoxic drugs‐>8.1.4 Vinca alkaloids and etoposide‐ Vinblastine On Formulary >VINBLASTINE SULFATE VINBLASTINE SULFATE On Formulary 8.1 Cytotoxic drugs‐>8.1.4 Vinca alkaloids and etoposide 8.1 Cytotoxic drugs‐>8.1.4 Vinca alkaloids and etoposide‐ Vincristine On Formulary >VINCRISTINE SULFATE VINCRISTINE SULFATE On Formulary 8.1 Cytotoxic drugs‐>8.1.4 Vinca alkaloids and etoposide VINORELBINE On Formulary 8.1 Cytotoxic drugs‐>8.1.4 Vinca alkaloids and etoposide 8.1 Cytotoxic drugs‐>8.1.4 Vinca alkaloids and etoposide‐ Vinorelbine On Formulary >VINORELBINE 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Non‐nucleoside reverse ViramuneÂ® On Formulary transcriptase inhibitors‐>NEVIRAPINE As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse VireadÂ® On Formulary transcriptase inhibitors‐>TENOFOVIR DISOPROXIL As per HIV guidelines.

11.8 Miscellaneous ophthalmic preparations‐>11.8.1 Tear deficiency, ViscotearsÂ® On Formulary ocular lubricants, and astringents‐>CARBOMERS 11.4 Corticosteroids and other anti‐inflammatory preparations‐ VistamethasoneÂ® On Formulary >11.4.1 Corticosteroids‐>BETAMETHASONE 12.1 Drugs acting on the ear‐>12.1.1 Otitis externa‐>Anti‐ inflammatory preparations‐>Corticosteroids‐>BETAMETHASONE VistamethasoneÂ® On Formulary SODIUM PHOSPHATE

12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ VistamethasoneÂ® On Formulary >Corticosteroids‐>BETAMETHASONE SODIUM PHOSPHATE 9.6 Vitamins‐>9.6.2 Vitamin B group‐>Oral vitamin B complex Vitamin B Tablets, Compound, Strong On Formulary preparations

Ascorbic acid injection not kept at the Vitamin COn Formulary 9.6 Vitamins RFH. See under thiamine (Pabrinex). Tocopheryl acetate 100mg/2ml Vitamin EOn Formulary 9.6 Vitamins injection also kept at the RFH. Tocopheryl acetate 100mg/2ml Vitamin E Suspension On Formulary 9.6 Vitamins‐>9.6.5 Vitamin E‐>ALPHA TOCOPHERYL ACETATE injection also kept at the RFH. Vitlipid NÂ® On Formulary 9.3 Intravenous nutrition‐>Supplementary preparations

10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ VoltarolÂ® On Formulary steroidal anti‐inflammatory drugs‐>DICLOFENAC SODIUM 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ steroidal anti‐inflammatory drugs‐>DICLOFENAC SODIUM‐>Modified VoltarolÂ® 75Â mg SR On Formulary release 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ steroidal anti‐inflammatory drugs‐>DICLOFENAC SODIUM‐>Modified VoltarolÂ® Retard On Formulary release 3.1 Bronchodilators‐>3.1.5 Peak flow meters, inhaler devices and VolumaticÂ® On Formulary nebulisers‐>Drug delivery devices

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

See Warfarin sodium for Warfarin initiation and maintenace protocol. 2.8 Anticoagulants and protamine‐>2.8.2 Oral anticoagulants‐ Protocol for Reversal of Warfarin Warfarin On Formulary >Coumarins and phenindione‐>WARFARIN SODIUM Anticoagulation

See Warfarin for protocol for Reversal 2.8 Anticoagulants and protamine‐>2.8.2 Oral anticoagulants‐ of Warfarin Anticoagulation Warfarin WARFARIN SODIUM On Formulary >Coumarins and phenindione initiation and maintenace

9.2 Fluids and electrolytes‐>9.2.2 Parenteral preparations for fluid Water for Injections On Formulary and electrolyte imbalance‐>9.2.2.1 Electrolytes and water‐>Water WaxsolÂ® On Formulary 12.1 Drugs acting on the ear‐>12.1.3 Removal of earwax Available at the RNTNE only.

WHO Oral Rehydration Powder is not kept at RFH but all ingredients are 9.2 Fluids and electrolytes‐>9.2.1 Oral preparations for fluid and available individually (i.e. sodium electrolyte imbalance‐>9.2.1.2 Oral sodium and water‐>Oral chloride, potassium chloride, sodium WHO formulation On Formulary rehydration therapy (ORT)‐>ORAL REHYDRATION SALTS (ORS) citrate and anhydrous glucose). 9.8 Metabolic disorders‐>9.8.1 Drugs used in metabolic disorders‐ WilzinÂ® On Formulary >Wilson's disease‐>ZINC ACETATE 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse With abacavir On Formulary transcriptase inhibitors‐>LAMIVUDINE As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse With abacavir and lamivudine On Formulary transcriptase inhibitors‐>ZIDOVUDINE As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse With abacavir and zidovudine On Formulary transcriptase inhibitors‐>LAMIVUDINE As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse With efavirenz and emtricitabine On Formulary transcriptase inhibitors‐>TENOFOVIR DISOPROXIL As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse With efavirenz and tenofovir disoproxil On Formulary transcriptase inhibitors‐>EMTRICITABINE As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse With emtricitabine On Formulary transcriptase inhibitors‐>TENOFOVIR DISOPROXIL As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Non‐nucleoside reverse With emtricitabine and tenofovir On Formulary transcriptase inhibitors‐>EFAVIRENZ As per HIV guidelines.

7.1 Drugs used in obstetrics‐>7.1.1 Prostaglandins and oxytocics‐ Royal Free Maternity Unit Guideline With ergometrine On Formulary >OXYTOCIN on Massive Obstetric Haemorrhage 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse With lamivudine On Formulary transcriptase inhibitors‐>ABACAVIR As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse With lamivudine On Formulary transcriptase inhibitors‐>ZIDOVUDINE As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse With lamivudine and zidovudine On Formulary transcriptase inhibitors‐>ABACAVIR As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors‐ With lopinavir On Formulary >RITONAVIR As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse With tenofovir disoproxil On Formulary transcriptase inhibitors‐>EMTRICITABINE As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse With zidovudine On Formulary transcriptase inhibitors‐>LAMIVUDINE As per HIV guidelines.

9.1 Anaemias and some other blood disorders‐>9.1.4 Drugs used in XagridÂ® On Formulary platelet disorders‐>Essential thrombocythaemia‐>ANAGRELIDE

7.4 Drugs for genito‐urinary disorders‐>7.4.1 Drugs for urinary XatralÂ® On Formulary retention‐>Alpha‐blockers‐>ALFUZOSIN HYDROCHLORIDE XelodaÂ® On Formulary 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites‐>CAPECITABINE 12.3 Drugs acting on the oropharynx‐>12.3.1 Drugs for oral ulceration XylocaineÂ® On Formulary and inflammation‐>LOCAL ANAESTHETICS 15.2 Local anaesthesia‐>Lidocaine‐>LIDOCAINE HYDROCHLORIDE‐ XylocaineÂ® On Formulary >With adrenaline 15.2 Local anaesthesia‐>Lidocaine‐>LIDOCAINE HYDROCHLORIDE‐ XylocaineÂ® On Formulary >Lidocaine for surface anaesthesia

12.2 Drugs acting on the nose‐>12.2.2 Topical nasal decongestants‐ Xylometazoline On Formulary >Sympathomimetics‐>XYLOMETAZOLINE HYDROCHLORIDE 12.2 Drugs acting on the nose‐>12.2.2 Topical nasal decongestants‐ XYLOMETAZOLINE HYDROCHLORIDE On Formulary >Sympathomimetics 1.3 Antisecretory drugs and mucosal protectants‐>1.3.1 H2‐receptor ZantacÂ® On Formulary antagonists‐>RANITIDINE 8.1 Cytotoxic drugs‐>8.1.2 Anthracyclines and other cytotoxic ZavedosÂ® On Formulary antibiotics‐>IDARUBICIN HYDROCHLORIDE 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse ZeffixÂ® On Formulary transcriptase inhibitors‐>LAMIVUDINE As per HIV guidelines. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse ZeritÂ® On Formulary transcriptase inhibitors‐>STAVUDINE As per HIV guidelines. 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme ZestrilÂ® On Formulary inhibitors‐>LISINOPRIL

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse ZiagenÂ® On Formulary transcriptase inhibitors‐>ABACAVIR As per HIV guidelines. 7.2 Treatment of vaginal and vulval conditions‐>7.2.2 Vaginal and vulval infections‐>Other infections‐>PREPARATIONS FOR OTHER ZidovalÂ® On Formulary VAGINAL INFECTIONS 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Nucleoside reverse ZIDOVUDINE On Formulary transcriptase inhibitors As per HIV guidelines. 4.1 Hypnotics and anxiolytics‐>4.1.1 Hypnotics‐>Zaleplon, zolpidem, ZimovaneÂ® On Formulary and zopiclone‐>ZOPICLONE 9.8 Metabolic disorders‐>9.8.1 Drugs used in metabolic disorders‐ ZINC ACETATE On Formulary >Wilson's disease 13.2 Emollient and barrier preparations‐>13.2.2 Barrier preparations‐ Zinc and Castor Oil Ointment, BP On Formulary >Non‐proprietary barrier preparations 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Salicylic acid‐>SALICYLIC Zinc and Salicylic Acid Paste, BP On Formulary ACID

13.5 Preparations for eczema and psoriasis‐>13.5.1 Preparations for Only Ichthamol Bandage available at Zinc Paste and Ichthammol Bandage, BP 1993 On Formulary eczema‐>Topical preparations for eczema‐>ICHTHAMMOL the RFH.

Only Ichthopaste Bandage available Zinc Paste and Ichthammol Bandage, BP 1993 On Formulary A5.8 Bandages‐>A5.8.9 Medicated bandages at the Royal Free Hospital.

Only Viscopaste Bandage available at Zinc Paste Bandage, BP 1993 On Formulary A5.8 Bandages‐>A5.8.9 Medicated bandages the Royal Free Hospital. Only oral preparations kept at the ZINC SULFATE On Formulary 9.5 Minerals‐>9.5.4 Zinc RFH. 13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐>Topical ZinerytÂ® On Formulary antibacterials for acne‐>ANTIBACTERIALS 4.3 Antidepressant drugs‐>4.3.4 Other antidepressant drugs‐ Zispin SolTabÂ® On Formulary >MIRTAZAPINE ZocorÂ® On Formulary 2.12 Lipid‐regulating drugs‐>Statins‐>SIMVASTATIN 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Gonadorelin ZoladexÂ® On Formulary analogues‐>GOSERELIN 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Gonadorelin ZoladexÂ® LA On Formulary analogues‐>GOSERELIN 4.1 Hypnotics and anxiolytics‐>4.1.1 Hypnotics‐>Zaleplon, zolpidem, ZOPICLONE On Formulary and zopiclone 4.1 Hypnotics and anxiolytics‐>4.1.1 Hypnotics‐>Zaleplon, zolpidem, Zopiclone On Formulary and zopiclone‐>ZOPICLONE 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Tazarotene‐ ZoracÂ® On Formulary >TAZAROTENE 1.3 Antisecretory drugs and mucosal protectants‐>1.3.5 Proton pump ZotonÂ® On Formulary inhibitors‐>LANSOPRAZOLE

ZoviraxÂ® On Formulary 11.3 Anti‐infective eye preparations‐>11.3.3 Antivirals‐>ACICLOVIR 13.10 Anti‐infective skin preparations‐>13.10.3 Antiviral preparations‐ ZoviraxÂ® On Formulary >ACICLOVIR

4.10 Drugs used in substance dependence‐>4.10.2 Nicotine ZybanÂ® On Formulary dependence‐>Bupropion‐>BUPROPION HYDROCHLORIDE

4.7 Analgesics‐>4.7.2 Opioid analgesics‐>TRAMADOL The orodispersible tablets are not ZydolÂ® On Formulary HYDROCHLORIDE available at The Royal Free Hospital. 10.1 Drugs used in rheumatic diseases and gout‐>10.1.4 Gout and cytotoxic‐induced hyperuricaemia‐>Long‐term control of gout‐ ZyloricÂ® On Formulary >ALLOPURINOL 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Anti‐ ZytigaÂ® On Formulary androgens‐>ABIRATERONE ACETATE Approved for rheumatoid arthritis, in 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that line with NICE guidance. PCT funding ABATACEPT Restricted suppress the rheumatic disease process‐>Cytokine modulators required. Restricted to use in the cardiology ABCIXIMAB Restricted 2.9 Antiplatelet drugs cath lab only. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>Second‐generation antipsychotic drugs‐ Initiate after discussion with liaison AbilifyÂ® Restricted >ARIPIPRAZOLE psychiatry team. 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme Restricted to scleroderma patients AccuproÂ® Restricted inhibitors‐>QUINAPRIL only. 13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial preparations‐>13.10.1.2 Antibacterial preparations also used Restricted for the treatment of AceaÂ® Restricted systemically‐>METRONIDAZOLE rosacea only.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Aciclovir INJECTION restricted to:Haematology; Oncology; Immunosuppressed transplant patients; HIV; Suspected viral meningitis/encephalitis; Dermatology 5.3 Antiviral drugs‐>5.3.2 Herpesvirus infections‐>5.3.2.1 Herpes (eczema herpeticum); Neonatology ACICLOVIR Restricted simplex and varicellaâ€“zoster infection (chickenpox).

Restricted to the HAS unit, vascular surgery and neurosurgery (Intra‐ 2.10 Stable angina, acute coronary syndromes, and fibrinolysis‐ arterial therapy for basilar artery ActilyseÂ® Restricted >2.10.2 Fibrinolytic drugs‐>ALTEPLASE thrombosis)

Prior funding approval required. Restricted to dermatology, 1.5 Chronic bowel disorders‐>1.5.3 Drugs affecting the immune gastroenterology, paediatric ADALIMUMAB Restricted response‐>Cytokine modulators gastroenterology and rheumatology.

Prior funding approval required. Restricted to dermatology, gastroenterology, paediatric 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that gastroenterology and rheumatology. ADALIMUMAB Restricted suppress the rheumatic disease process‐>Cytokine modulators NICE

ADEFOVIR DIPIVOXIL Restricted 5.3 Antiviral drugs‐>5.3.3 Viral hepatitis‐>5.3.3.1 Chronic hepatitis B Restricted to Hepatology/Virology.

Restricted to individual patients 8.2 Drugs affecting the immune response‐>8.2.2 Corticosteroids and identified by the renal and liver AdvagrafÂ® Restricted other immunosuppressants‐>TACROLIMUS‐>Modified release transplantation teams only. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase AFATINIB Restricted inhibitors

Prior funding approval required. Restricted to oncology. Approved for pancreatic NET (as part of compassionate access program). Also 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase approved for renal cell carcinoma in AfinitorÂ® Restricted inhibitors‐>EVEROLIMUS line with NICE guidance. AggrastatÂ® Restricted 2.9 Antiplatelet drugs‐>TIROFIBAN Restricted to cardiology only. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Taxanes‐ Albumin‐bound formulation Restricted >PACLITAXEL Restricted to breast cancer patients

Prior funding approval required. Restricted for the treatment of mesothelioma and non‐small cell lung cancer in combination with cisplatin AlimtaÂ® Restricted 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites‐>PEMETREXED only.

4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant Initiate after discussion with liaison AllegronÂ® Restricted drugs‐>Tricyclic antidepressants‐>NORTRIPTYLINE psychiatry team. 7.4 Drugs for genito‐urinary disorders‐>7.4.5 Drugs for erectile Restricted to Urology and Alprostadil Restricted dysfunction Endocrinology consultants 7.4 Drugs for genito‐urinary disorders‐>7.4.5 Drugs for erectile Restricted to Urology and ALPROSTADIL Restricted dysfunction‐>Alprostadil Endocrinology consultants

Restricted to the HAS unit, vascular surgery and neurosurgery (Intra‐ arterial therapy for basilar artery 2.10 Stable angina, acute coronary syndromes, and fibrinolysis‐ thrombosis)For alteplase protocols ALTEPLASE Restricted >2.10.2 Fibrinolytic drugs see under Actilyse. 9.5 Minerals‐>9.5.2 Phosphorus‐>9.5.2.2 Phosphate‐binding agents‐ Alu‐CapÂ® Restricted >ALUMINIUM HYDROXIDE Restricted to renal patients only.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

ALUMINIUM HYDROXIDE Restricted 9.5 Minerals‐>9.5.2 Phosphorus‐>9.5.2.2 Phosphate‐binding agents Restricted to renal patients only.

Restricted to Haematology; Oncology; HIV; Haematology; ERCP prophylaxis. 5.2 Antifungal drugs‐>5.2.3 Polyene antifungals‐>AMPHOTERICIN‐ Microbiology/ID approval required AmBisomeÂ® Restricted >Lipid formulations for all other indications.

Prior funding approval required. 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator Restricted to the treatment of AMBRISENTAN Restricted antihypertensive drugs pulmonary hypertension.

Restricted to Opthalmology (intracameral); HIV; Haematology; ERCP prophylaxis. Microbiology approval required for all other indications. RFL Adult aminoglycoside AMIKACIN Restricted 5.1 Antibacterial drugs‐>5.1.4 Aminoglycosides dosing guideline

Restricted to Opthalmology (intracameral); HIV; Haematology; ERCP prophylaxis. Microbiology approval required for all other indications. RFL Adult aminoglycoside Amikacin Restricted 5.1 Antibacterial drugs‐>5.1.4 Aminoglycosides‐>AMIKACIN dosing guideline

Restricted to Opthalmology (intracameral); HIV; Haematology; ERCP prophylaxis. Microbiology approval required for all other indications.For therapeutic drug monitoring please refer to the RFH Antibiotic Prescribing Aid. Antibiotic AmikinÂ® Restricted 5.1 Antibacterial drugs‐>5.1.4 Aminoglycosides‐>AMIKACIN prescribing aid RFL Adult aminoglycoside dosing Aminoglycosides Restricted 5.1 Antibacterial drugs guideline

4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison AMISULPRIDE Restricted Antipsychotic drugs‐>Second‐generation antipsychotic drugs psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>Second‐generation antipsychotic drugs‐ Initiate after discussion with liaison Amisulpride Restricted >AMISULPRIDE psychiatry team.

Restricted antimicrobial agent.Only 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal the nail lacquer is available at The AMOROLFINE Restricted preparations Royal Free Hospital. 13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial preparations‐>13.10.1.2 Antibacterial preparations also used Restricted for the treatment of AnabactÂ® Restricted systemically‐>METRONIDAZOLE rosacea only.

Prior funding approval required. Restricted to use by the Amyloidosis 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that centre only.Not approved for use in ANAKINRA Restricted suppress the rheumatic disease process‐>Cytokine modulators rheumatoid arthritis.

Restricted to HIV; Haematology; Oncology; Transplant patients. Microbiology approval required for all AncotilÂ® Restricted 5.2 Antifungal drugs‐>5.2.5 Other antifungals‐>FLUCYTOSINE other indications. 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ Restricted to use in the cardiology AngioxÂ® Restricted >Hirudins‐>BIVALIRUDIN cath lab only. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>First‐generation antipsychotic drugs‐ Initiate after discussion with liaison AnquilÂ® Restricted >BENPERIDOL psychiatry team. Anti‐obesity drugs acting on the gastro‐ intestinal tract Restricted 4.5 Obesity Restricted to the Lipid Clinic Only. Azelastine is restricted to the allergy Antihistamines Restricted 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy clinic only. Initiate after discussion with liaison Antipsychotic depot injections Restricted 4.2 Drugs used in psychoses and related disorders psychiatry team. Initiate after discussion with liaison Antipsychotic drugs Restricted 4.2 Drugs used in psychoses and related disorders psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.3 Drugs used Initiate after discussion with liaison Antipsychotic drugs Restricted for mania and hypomania psychiatry team. Initiate after discussion with liaison Anxiolytics Restricted 4.1 Hypnotics and anxiolytics psychiatry team.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

11.8 Miscellaneous ophthalmic preparations‐>11.8.2 Ocular diagnostic and peri‐operative preparations and photodynamic APRACLONIDINE Restricted treatment‐>Ocular peri‐operative drugs 1% restricted to Opthalmology. 4.6 Drugs used in nausea and vertigo‐>Neurokinin‐receptor Restricted to oncology and APREPITANT Restricted antagonists haematology only. 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.2 Angiotensin‐II receptor antagonists‐ AprovelÂ® Restricted >IRBESARTAN Restriced to renal patients only. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors‐ Restricted to use as per London HIV AptivusÂ® Restricted >TIPRANAVIR consortium guidelines. 9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in hypoplastic, haemolytic, and renal anaemias‐>Erythropoietins‐ AranespÂ® Restricted >DARBEPOETIN ALFA Restricted to renal team only

4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison ARIPIPRAZOLE Restricted Antipsychotic drugs‐>Second‐generation antipsychotic drugs psychiatry team.

2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ Restricted ‐ only to be used under the ArixtraÂ® Restricted >Fondaparinux‐>FONDAPARINUX SODIUM advice of the haemophilia consultant Arsenic trioxide Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs Prior funding approval required 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Arsenic ARSENIC TRIOXIDE Restricted trioxide Prior funding approval required 2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ >Supraventricular and ventricular arrhythmias‐>PROPAFENONE ArythmolÂ® Restricted HYDROCHLORIDE Restricted to cardiology only.

AsmanexÂ® Restricted 3.2 Corticosteroids‐>MOMETASONE FUROATE Restricted to Thoracic Medicine only.

Asparaginase, crisantaspase and pegaspargase Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs Restricted to the Child & 4.4 CNS stimulants and drugs used for attention deficit hyperactivity Adolescent Mental Health Service ATOMOXETINE Restricted disorder only. Use is restricted to HIV, Renal, and lipid clinic patients, as well as suspected simvastatin intolerance and drug interactions. Statin ATORVASTATIN Restricted 2.12 Lipid‐regulating drugs‐>Statins prescribing

ATOVAQUONE Restricted 5.4 Antiprotozoal drugs‐>5.4.8 Drugs for pneumocystis pneumonia ID/Microbiology approval only. 13.4 Topical corticosteroids‐>TRIAMCINOLONE ACETONIDE‐>With Restricted to Dermatology AureocortÂ® Restricted antimicrobials Outpatients only.

Restricted to thoracic medicine. ID/Microbiology approval required AveloxÂ® Restricted 5.1 Antibacterial drugs‐>5.1.12 Quinolones‐>MOXIFLOXACIN for all other indications. Approved by Dermatology for frontal 6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists‐>Anti‐ fibrosing alopecia (third line drug, off AvodartÂ® Restricted androgens‐>Dutasteride and finasteride‐>DUTASTERIDE label use) 8.2 Drugs affecting the immune response‐>8.2.4 Other immunomodulating drugs‐>Interferon beta‐>INTERFERON BETA‐ AvonexÂ® Restricted >Interferon beta‐1a Prior funding approval required 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase AXITINIB Restricted inhibitors Approved for Haematology for MDS, AZACITIDINE Restricted 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites CMML and AML only 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and other beta‐lactams‐>5.1.2.3 Other beta‐lactam antibiotics‐ AzactamÂ® Restricted >AZTREONAM‐>Parenteral Microbiology approval only. 12.2 Drugs acting on the nose‐>12.2.1 Drugs used in nasal allergy‐ AZELASTINE HYDROCHLORIDE Restricted >Antihistamines Restricted to the allergy clinic only.

Restricted to Marlborough OPD; Obs & Gynae (TOP); Renal transplant. Microbiology approval AZITHROMYCIN Restricted 5.1 Antibacterial drugs‐>5.1.5 Macrolides required for all other indications.

Restricted to Marlborough OPD; Obs & Gynae (TOP); Renal transplant. Microbiology approval Azithromycin Restricted 5.1 Antibacterial drugs‐>5.1.5 Macrolides‐>AZITHROMYCIN required for all other indications.

5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and AZTREONAM Restricted other beta‐lactams‐>5.1.2.3 Other beta‐lactam antibiotics Microbiology approval only.

Restricted to Dermatology outpatients for impetigo only. Maximum 14 days prescription.Only 13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial the ointment is kept at The Royal preparations‐>13.10.1.1 Antibacterial preparations only used Free Hospital.See Section 12.2.3 for BactrobanÂ® Restricted topically‐>MUPIROCIN Mupirocin Nasal Ointment.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Prior funding required for treatment of lymphoma with radiolabelled 8.2 Drugs affecting the immune response‐>8.2.2 Corticosteroids and basiliximabApproved for Renal BASILIXIMAB Restricted other immunosuppressants transplant patients. Approved for Haematology for indolent NHL, PCT funding approval BENDAMUSTINE HYDROCHLORIDE Restricted 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs required 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison BENPERIDOL Restricted Antipsychotic drugs‐>First‐generation antipsychotic drugs psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.3 Drugs used Initiate after discussion with liaison Benzodiazepines Restricted for mania and hypomania psychiatry team. 8.2 Drugs affecting the immune response‐>8.2.4 Other immunomodulating drugs‐>Interferon beta‐>INTERFERON BETA‐ BetaferonÂ® Restricted >Interferon beta‐1b Prior funding approval required Metoprolol injection restricted to BetalocÂ® Restricted 2.4 Beta‐adrenoceptor blocking drugs‐>METOPROLOL TARTRATE cardiology and ITU only. Bevacizumab Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs Bexarotene Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs Prior funding approval required

BEXAROTENE Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Bexarotene Prior funding approval required 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ Restricted to use in the cardiology BIVALIRUDIN Restricted >Hirudins cath lab only. Bortezomib Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs Prior funding approval required

BORTEZOMIB Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Bortezomib Prior funding approval required

Prior funding approval required. 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator Restricted to the treatment of BOSENTAN Restricted antihypertensive drugs pulmonary hypertension. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase BOSUTINIB Restricted inhibitors

4.9 Drugs used in parkinsonism and related disorders‐>4.9.3 Drugs Approved for anal fissures, hand used in essential tremor, chorea, tics, and related disorders‐>Torsion spasticity patients with scleraderma, dystonias and other involuntary movements‐>BOTULINUM TOXIN gastroparesis, female urology BotoxÂ® Restricted TYPE A patients and hyperhidrosis.

4.9 Drugs used in parkinsonism and related disorders‐>4.9.3 Drugs used in essential tremor, chorea, tics, and related disorders‐>Torsion BOTULINUM TOXIN TYPE A Restricted dystonias and other involuntary movements See individual preparation Brentuximab vedotin Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Brentuximab BRENTUXIMAB VEDOTIN Restricted vedotin Restricted to ITU, cardiology and BreviblocÂ® Restricted 2.4 Beta‐adrenoceptor blocking drugs‐>ESMOLOL HYDROCHLORIDE theatre 8 only.

Bricanyl Respules® are 3.1 Bronchodilators‐>3.1.1 Adrenoceptor agonists‐>3.1.1.1 Selective RESTRICTED for use in paediatrics and BricanylÂ® Restricted beta2 agonists‐>TERBUTALINE SULFATE‐>Inhalation patients with poor manual dexterity. 15.1 General anaesthesia‐>15.1.6 Drugs for reversal of neuromuscular blockade‐>Other drugs for reversal of neuromuscular blockade‐ BridionÂ® Restricted >SUGAMMADEX Restricted to Theatres 4.6 Drugs used in nausea and vertigo‐>Phenothiazines and related BuccastemÂ® Restricted drugs‐>PROCHLORPERAZINE‐>Buccal preparation Restricted to ENT only.

Budesonide rectal foam enema is BudenofalkÂ® Restricted 1.5 Chronic bowel disorders‐>1.5.2 Corticosteroids‐>BUDESONIDE restricted to Dr Mark Hamilton 6.7 Other endocrine drugs‐>6.7.2 Drugs affecting gonadotrophins‐ Restricted to consultant BUSERELIN Restricted >Gonadorelin analogues gynaecologists only. Prior funding approval required via CABAZITAXEL Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Taxanes CDF 6.7 Other endocrine drugs‐>6.7.1 Bromocriptine and other Restricted to Endocrinology and CABERGOLINE Restricted dopaminergic drugs Gynaecology. 6.7 Other endocrine drugs‐>6.7.1 Bromocriptine and other Restricted to Endocrinology and Cabergoline Restricted dopaminergic drugs‐>CABERGOLINE Gynaecology. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase CABOZANTINIB Restricted inhibitors 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Vitamin D and Calcipotriol Restricted analogues‐>CALCIPOTRIOL Restricted to Dermatology only. 9.5 Minerals‐>9.5.1 Calcium and magnesium‐>9.5.1.1 Calcium Calcium‐500 Restricted supplements‐>CALCIUM SALTS‐>Oral preparations Restricted to renal patients only. 9.5 Minerals‐>9.5.2 Phosphorus‐>9.5.2.2 Phosphate‐binding agents‐ Calcium‐500 Restricted >CALCIUM SALTS Restricted to renal patients only. Restricted to Rheumatology and CalcortÂ® Restricted 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy‐>DEFLAZACORT Endocrinology only. 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other CANAGLIFLOZIN Restricted antidiabetic drugs Restricted to Endocrinology

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

8.2 Drugs affecting the immune response‐>8.2.4 Other Prior funding approval required. Canakinumab Restricted immunomodulating drugs Approved for Professor Hawkins

8.2 Drugs affecting the immune response‐>8.2.4 Other Prior funding approval required. CANAKINUMAB Restricted immunomodulating drugs‐>Canakinumab Approved for Professor Hawkins

Restricted to Haematology (in discussion with Microbiology, as per protocol). Microbiology approval CancidasÂ® Restricted 5.2 Antifungal drugs‐>5.2.4 Echinocandin antifungals‐>CASPOFUNGIN required for all other indications. 13.9 Shampoos and other preparations for scalp and hair conditions‐ Restricted to dermatology patients CapasalÂ® Restricted >Shampoos only. CAPREOMYCIN Restricted 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs ID/Microbiology approval only. 4.2 Drugs used in psychoses and related disorders‐>4.2.3 Drugs used Initiate after discussion with liaison Carbamazepine Restricted for mania and hypomania psychiatry team. Carfilzomib Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs Restricted to Neurosurgery Restricted CARMUSTINE Restricted 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs to Haematology.

Restricted to Haematology (in discussion with Microbiology, as per protocol). Microbiology approval CASPOFUNGIN Restricted 5.2 Antifungal drugs‐>5.2.4 Echinocandin antifungals required for all other indications.

7.4 Drugs for genito‐urinary disorders‐>7.4.5 Drugs for erectile Restricted to Urology and CaverjectÂ® Restricted dysfunction‐>Alprostadil‐>ALPROSTADIL‐>Intracavernosal injection Endocrinology consultants Restricted to Marlborough OPD and 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and used for IV/PO switch with CEFIXIME Restricted other beta‐lactams‐>5.1.2.1 Cephalosporins Microbiology approval only.

Restricted to Neonates and Liver unit, 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and Microbiology approval required in all CEFOTAXIME Restricted other beta‐lactams‐>5.1.2.1 Cephalosporins other indications.

Restricted to Neonates and Liver unit, 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and Microbiology approval required in all Cefotaxime Restricted other beta‐lactams‐>5.1.2.1 Cephalosporins‐>CEFOTAXIME other indications. Restricted to Haematology. 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and Microbiology approval required for all CEFTAZIDIME Restricted other beta‐lactams‐>5.1.2.1 Cephalosporins other indications.

5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and Ceftazidime Restricted other beta‐lactams‐>5.1.2.1 Cephalosporins‐>CEFTAZIDIME Microbiology approval only.

Restricted for use in Meningitis; Brain abscess; Obstetrics; Liver Unit; Pelvic Inflammatory Disease, Paediatrics. 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and Microbiology approval required for all Ceftriaxone Restricted other beta‐lactams‐>5.1.2.1 Cephalosporins‐>CEFTRIAXONE other indications. 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ CelebrexÂ® Restricted steroidal anti‐inflammatory drugs‐>CELECOXIB For rheumatology use only 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ CELECOXIB Restricted steroidal anti‐inflammatory drugs For rheumatology use only 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Other antiretrovirals‐ Restricted to use as per London HIV CelsentriÂ® Restricted >MARAVIROC consortium guidelines.

7.3 Contraceptives‐>7.3.2 Progestogen‐only contraceptives‐>7.3.2.1 Approved for Sexual Healtha nd Oral progestogen‐only contraceptives‐>ORAL PROGESTOGEN‐ONLY Family Planning (Marlborough Clinic). CerazetteÂ® Restricted CONTRACEPTIVES Also approved for Obs and Gyn. Approved for rheumatoid arthritis in 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that line with NICE guidance. PCT funding CERTOLIZUMAB PEGOL Restricted suppress the rheumatic disease process‐>Cytokine modulators required.

Restricted to haematology for the CETRORELIX Restricted 6.7 Other endocrine drugs‐>6.7.2 Drugs affecting gonadotrophins preservation of female fertility.

6.7 Other endocrine drugs‐>6.7.2 Drugs affecting gonadotrophins‐ Restricted to haematology for the CetrotideÂ® Restricted >CETRORELIX preservation of female fertility.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Prior funding approval required NICE guidance ‐ Cetuximab for the first‐line treatment of metastatic colorectal Cetuximab Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs cancer

Systemic use restricted to Neurology; Neurosurgery; Paediatrics. Microbiology approval required for all Chloramphenicol Restricted 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials other indications.

Systemic use restricted to Neurology; Neurosurgery; Paediatrics. 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐ Microbiology approval required for all CHLORAMPHENICOL Restricted >Chloramphenicol other indications.

Systemic use restricted to Neurology; Neurosurgery; Paediatrics. 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐ Microbiology approval required for all Chloramphenicol Restricted >Chloramphenicol‐>CHLORAMPHENICOL other indications. 4.1 Hypnotics and anxiolytics‐>4.1.2 Anxiolytics‐>Benzodiazepines‐ Restricted to in‐patient use for Chlordiazepoxide Restricted >CHLORDIAZEPOXIDE HYDROCHLORIDE alcohol detoxification. Restricted to in‐patient use for CHLORDIAZEPOXIDE HYDROCHLORIDE Restricted 4.1 Hypnotics and anxiolytics‐>4.1.2 Anxiolytics‐>Benzodiazepines alcohol detoxification.

Initiate after discussion with liaison 4.2 Drugs used in psychoses and related disorders‐>4.2.1 psychiatry team.The suppositories CHLORPROMAZINE HYDROCHLORIDE Restricted Antipsychotic drugs‐>First‐generation antipsychotic drugs are not kept at the RFH.

7.4 Drugs for genito‐urinary disorders‐>7.4.5 Drugs for erectile For Urology and Endocrinology use CialisÂ® Restricted dysfunction‐>Phosphodiesterase type‐5 inhibitors‐>TADALAFIL only

1.3 Antisecretory drugs and mucosal protectants‐>1.3.1 H2‐receptor 200mg and 400mg tablets availble. Cimetidine Restricted antagonists‐>CIMETIDINE The 800mg tablets are not available 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that Approved for rheumatoid arthritis in suppress the rheumatic disease process‐>Cytokine modulators‐ line with NICE guidance. PCT funding CimziaÂ® Restricted >CERTOLIZUMAB PEGOL required. Under Professor Cunningham's 9.5 Minerals‐>9.5.1 Calcium and magnesium‐>9.5.1.2 Hypercalcaemia recommendation and approved for CINACALCET Restricted and hypercalciuria endocrinology.

Restricted to Haematology; HIV; Immunology; Oncology; Malignant otitis externa; Necrotising fascitis; Endopthalmitis; Prophylaxis in SBP and leech therapy; Epidydymo‐ orchitis; Prostatitis; ERCP prophylaxis. Microbiology approval required for all CIPROFLOXACIN Restricted 5.1 Antibacterial drugs‐>5.1.12 Quinolones other indications.

Restricted to Haematology; HIV; Immunology; Oncology; Malignant otitis externa; Necrotising fascitis; Endopthalmitis; Prophylaxis in SBP and leech therapy; Epidydymo‐ orchitis; Prostatitis; ERCP prophylaxis. Microbiology approval required for all Ciprofloxacin Restricted 5.1 Antibacterial drugs‐>5.1.12 Quinolones‐>CIPROFLOXACIN other indications.

Restricted to Haematology; HIV; Immunology; Oncology; Malignant otitis externa; Necrotising fascitis; Endopthalmitis; Prophylaxis in SBP and leech therapy; Epidydymo‐ orchitis; Prostatitis; ERCP prophylaxis. Microbiology approval required for all CiproxinÂ® Restricted 5.1 Antibacterial drugs‐>5.1.12 Quinolones‐>CIPROFLOXACIN other indications.

For treatment of acute coronary 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ syndrome only. Low molecular weight ClexaneÂ® Restricted >Low molecular weight heparins‐>ENOXAPARIN SODIUM heparin protocol

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Restricted to HIV; Necrotising fascitis; Endocarditis prophylaxis. In Beta‐ lactam allergy for: Aspiration pneumonia; Surgical prophylaxis in Obstetrics and Plastic surgery. Topical use by Dermatology. Microbiology approval required for all other Clindamycin Restricted 5.1 Antibacterial drugs indications.

Restricted to HIV; Necrotising fascitis; Endocarditis prophylaxis; Beta‐lactam allergy; Aspiration pneumonia; Surgical prophylaxis in Obstetrics and Plastic surgery; Topical use by Dermatology. Microbiology approval Clindamycin Restricted 5.1 Antibacterial drugs‐>5.1.6 Clindamycin‐>CLINDAMYCIN required for all other indications. 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ Blacklist restriction except in CLOBAZAM Restricted >Benzodiazepines epilepsy. 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ Blacklist restriction except in Clobazam Restricted >Benzodiazepines‐>CLOBAZAM epilepsy. CLOFARABINE Restricted 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites CLOFAZIMINE Restricted 5.1 Antibacterial drugs‐>5.1.10 Antileprotic drugs Microbiology/ID approval only.

Clofazimine Restricted 5.1 Antibacterial drugs‐>5.1.10 Antileprotic drugs‐>CLOFAZIMINE Microbiology/ID approval only. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>First‐generation antipsychotic drugs‐ Initiate after discussion with liaison Clopixol AcuphaseÂ® Restricted >ZUCLOPENTHIXOL ACETATE psychiatry team.

4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison Clopixol Conc.Â® Restricted Antipsychotic depot injections‐>ZUCLOPENTHIXOL DECANOATE psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>First‐generation antipsychotic drugs‐ Initiate after discussion with liaison ClopixolÂ® Restricted >ZUCLOPENTHIXOL psychiatry team.

4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison ClopixolÂ® Restricted Antipsychotic depot injections‐>ZUCLOPENTHIXOL DECANOATE psychiatry team.

Initiate after discussion with liaison psychiatry team. If a patient is admitted on this therapy please ensure that the pharmacy mental health team are aware. Patients being treated in the UK will be registered 4.2 Drugs used in psychoses and related disorders‐>4.2.1 with CPMS (Clozaril Patient CLOZAPINE Restricted Antipsychotic drugs‐>Second‐generation antipsychotic drugs Monitoring Service).

Initiate after discussion with liaison psychiatry team. If a patient is admitted on this therapy please ensure that the pharmacy mental health team are aware. Patients being 4.2 Drugs used in psychoses and related disorders‐>4.2.1 treated in the UK will be registered Antipsychotic drugs‐>Second‐generation antipsychotic drugs‐ with CPMS (Clozaril Patient ClozarilÂ® Restricted >CLOZAPINE Monitoring Service). 1.6 Laxatives‐>1.6.2 Stimulant laxatives‐>DANTRON‐>With poloxamer Restricted to oncologist and Co‐danthramer Restricted â€˜188â€™ (as co‐danthramer) geriatricians Restricted to treatment and prevention of PCP infection; Chemotherapy protocols. Microbiology approval required for all CO‐TRIMOXAZOLE Restricted 5.1 Antibacterial drugs‐>5.1.8 Sulfonamides and trimethoprim other indications. Restricted to treatment and prevention of PCP infection; Chemotherapy protocols. 5.1 Antibacterial drugs‐>5.1.8 Sulfonamides and trimethoprim‐>CO‐ Microbiology approval required for all Co‐trimoxazole Restricted TRIMOXAZOLE other indications. 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐>Polymyxins‐ ColomycinÂ® Restricted >COLISTIMETHATE SODIUM Microbiology approval only.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Restricted to the Child & 4.4 CNS stimulants and drugs used for attention deficit hyperactivity Adolescent Mental Health Service ConcertaÂ® XL Restricted disorder‐>METHYLPHENIDATE HYDROCHLORIDE‐>Modified release only. 13.7 Preparations for warts and calluses‐>Anogenital warts‐ CondylineÂ® Restricted >PODOPHYLLOTOXIN Restricted to Dermatology only. 8.2 Drugs affecting the immune response‐>8.2.4 Other immunomodulating drugs‐>Glatiramer acetate‐>GLATIRAMER CopaxoneÂ® Restricted ACETATE Prior funding approval required Virology/Microbiology/ID approval CopegusÂ® Restricted 5.3 Antiviral drugs‐>5.3.5 Respiratory syncytial virus‐>RIBAVIRIN only. CrestorÂ® Restricted 2.12 Lipid‐regulating drugs‐>Statins‐>ROSUVASTATIN Restricted to the lipid clinic. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase CRIZOTINIB Restricted inhibitors 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐>Daptomycin CubicinÂ® Restricted >DAPTOMYCIN Microbiology approval required. 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Vitamin D and Restricted to Dermatology and CuratodermÂ® Restricted analogues‐>TACALCITOL Rheumatology only. 3.5 Respiratory stimulants and pulmonary surfactants‐>3.5.2 CurosurfÂ® Restricted Pulmonary surfactants‐>PORACTANT ALFA Restricted to The Neonatal Unit. CutivateÂ® Restricted 13.4 Topical corticosteroids‐>FLUTICASONE PROPIONATE Restricted to paediatrics only. 9.1 Anaemias and some other blood disorders‐>9.1.2 Drugs used in Refer to blacklist exemptions under CYANOCOBALAMIN Restricted megaloblastic anaemias preparations.

9.1 Anaemias and some other blood disorders‐>9.1.2 Drugs used in Refer to blacklist exemptions listed Cyanocobalamin Restricted megaloblastic anaemias‐>CYANOCOBALAMIN below CYCLOSERINE Restricted 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs ID/Microbiology approval only.

Cycloserine Restricted 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs‐>CYCLOSERINE ID/Microbiology approval only. Restricted to HIV; Haematology; Oncology; Liver and Renal Transplants; Other immunosuppressed patients. Virology 5.3 Antiviral drugs‐>5.3.2 Herpesvirus infections‐>5.3.2.2 approval required for all other CymeveneÂ® Restricted Cytomegalovirus infection‐>GANCICLOVIR indications. 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that Cytokine modulators Restricted suppress the rheumatic disease process See individual drug for details. 13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐>Topical Dalacin TÂ® Restricted antibacterials for acne‐>ANTIBACTERIALS Restricted to Dermatology only. 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ See protocol for indications DANAPAROID SODIUM Restricted >Heparinoids Danaparoid protocol Restricted to oncologist and DANTRON Restricted 1.6 Laxatives‐>1.6.2 Stimulant laxatives geriatricians 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other DAPAGLIFLOZIN Restricted antidiabetic drugs Restricted to Endocrinology DAPSONE Restricted 5.1 Antibacterial drugs‐>5.1.10 Antileprotic drugs Microbiology/ID approval only.

Dapsone Restricted 5.1 Antibacterial drugs‐>5.1.10 Antileprotic drugs‐>DAPSONE Microbiology/ID approval only.

Daptomycin Restricted 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials Microbiology approval required.

DAPTOMYCIN Restricted 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐>Daptomycin Microbiology approval required.

9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in DARBEPOETIN ALFA Restricted hypoplastic, haemolytic, and renal anaemias‐>Erythropoietins Restricted to renal team only Restricted to use as per London HIV DARUNAVIR Restricted 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors consortium guidelines.

Prior funding approval required. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase Approved for imatinib‐resistant ALL, DASATINIB Restricted inhibitors and imatinib‐intolerant ALL,

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.2 Posterior pituitary hormones and antagonists‐>Posterior pituitary Restricted to child healthSublingual DDAVPÂ® Restricted hormones‐>DESMOPRESSIN tablets not available at RFH.

9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in DEFERASIROX Restricted hypoplastic, haemolytic, and renal anaemias‐>Iron overload Prior funding approval required. Restricted to Rheumatology and DEFLAZACORT Restricted 6.3 Corticosteroids‐>6.3.2 Glucocorticoid therapy Endocrinology only. 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐ DEGARELIX Restricted >Gonadotrophin‐releasing hormone antagonists Restricted to urology and Dr Pigott.

6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and Approved for osteoporosis treatment DENOSUMAB Restricted other drugs affecting bone metabolism‐>Denosumab by Endocrinology, Rheumatology

4.2 Drugs used in psychoses and related disorders‐>4.2.3 Drugs used Initiate after discussion with liaison DepakoteÂ® Restricted for mania and hypomania‐>Valproate‐>VALPROIC ACID psychiatry team.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison Depixol Conc.Â® Restricted Antipsychotic depot injections‐>FLUPENTIXOL DECANOATE psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison DepixolÂ® Restricted Antipsychotic depot injections‐>FLUPENTIXOL DECANOATE psychiatry team. 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.3 Somatostatin analogues‐ Prior funding approval required. First Depot preparation Restricted >OCTREOTIDE dose free of charge 13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐ Restricted to Paediatric Dermatology DermamistÂ® Restricted >Proprietary emollient preparations outpatients. 9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in hypoplastic, haemolytic, and renal anaemias‐>Iron overload‐ Prior funding approval required for DesferalÂ® Restricted >DESFERRIOXAMINE MESILATE desferrioxamine infusors

9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in Prior funding approval required for DESFERRIOXAMINE MESILATE Restricted hypoplastic, haemolytic, and renal anaemias‐>Iron overload desferrioxamine infusors. 9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in hypoplastic, haemolytic, and renal anaemias‐>Iron overload‐ Prior funding approval required for Desferrioxamine mesilate Restricted >DESFERRIOXAMINE MESILATE desferrioxamine infusors

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.2 Posterior pituitary hormones and antagonists‐>Posterior pituitary DesmotabsÂ® Restricted hormones‐>DESMOPRESSIN Restricted to child health.

10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Restricted to only Rheumatology and Diclofenac Sodium Restricted steroidal anti‐inflammatory drugs‐>DICLOFENAC SODIUM Obs / Gynae 11.8 Miscellaneous ophthalmic preparations‐>11.8.2 Ocular diagnostic and peri‐operative preparations and photodynamic DICLOFENAC SODIUM Restricted treatment‐>Ocular peri‐operative drugs Restricted to Opthalmology. 13.8 Sunscreens and camouflagers‐>13.8.1 Sunscreen preparations‐ DICLOFENAC SODIUM Restricted >Photodamage Restricted to Dermatologists.

13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐>Topical DifferinÂ® Restricted retinoids and related preparations for acne‐>ADAPALENE Restricted to Dermatology only.

INTRAVENOUS preparations restricted to Haematology; Oncology; HIV; Renal unit; Liver unit. Microbiology approval required for all DiflucanÂ® Restricted 5.2 Antifungal drugs‐>5.2.1 Triazole antifungals‐>FLUCONAZOLE other indications.

Diloxanide Restricted 5.4 Antiprotozoal drugs‐>5.4.2 Amoebicides‐>DILOXANIDE FUROATE Microbiology/ID approval only. DILOXANIDE FUROATE Restricted 5.4 Antiprotozoal drugs‐>5.4.2 Amoebicides Microbiology/ID approval only. Restricted for treatment of breast, prostate and non‐small cell DOCETAXEL Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Taxanes lung cancers Only available for liver transplant 2.7 Sympathomimetics‐>2.7.1 Inotropic sympathomimetics‐ patients and continuation of DopacardÂ® Restricted >DOPEXAMINE HYDROCHLORIDE treatment. Only available for liver transplant patients and continuation of DOPEXAMINE HYDROCHLORIDE Restricted 2.7 Sympathomimetics‐>2.7.1 Inotropic sympathomimetics treatment. 2.5 Hypertension and heart failure‐>2.5.4 Alpha‐adrenoceptor Restricted to urology only. Only 20mg DoraleseÂ® Restricted blocking drugs‐>INDORAMIN tablets kept at the RFH. 7.4 Drugs for genito‐urinary disorders‐>7.4.1 Drugs for urinary DoraleseÂ® Restricted retention‐>Alpha‐blockers‐>INDORAMIN Restricted to urologist only. 6.7 Other endocrine drugs‐>6.7.1 Bromocriptine and other Restricted to Endocrinology and DostinexÂ® Restricted dopaminergic drugs‐>CABERGOLINE Gynaecology.

13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Vitamin D and DovobetÂ® Restricted analogues‐>CALCIPOTRIOL‐>With betamethasone Restricted to Dermatology only. 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Vitamin D and DovonexÂ® Restricted analogues‐>CALCIPOTRIOL Restricted to Dermatology only. Initiate after discussion with liaison Drugs used for mania and hypomania Restricted 4.2 Drugs used in psychoses and related disorders psychiatry team. Initiate after discussion with liaison Drugs used in psychoses and related disorders Restricted psychiatry team. Drugs used to mobilise stem cells Restricted 9.1 Anaemias and some other blood disorders Restricted to BMT only. 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Levodopa‐>CO‐ DuodopaÂ® Restricted CARELDOPA‐>For use with enteral tube Prior funding approval required.

Approved for use by Dermatology for 6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists‐>Anti‐ frontal fibrosing alopecia (third line DUTASTERIDE Restricted androgens‐>Dutasteride and finasteride drug. Off label use) 4.9 Drugs used in parkinsonism and related disorders‐>4.9.3 Drugs used in essential tremor, chorea, tics, and related disorders‐>Torsion dystonias and other involuntary movements‐>BOTULINUM TOXIN Approved for neurology and DysportÂ® Restricted TYPE A ophthalmology use only

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

EbixaÂ® Restricted 4.11 Dementia‐>MEMANTINE HYDROCHLORIDE Mental health trust formulary only. Approved for the pallative care and EffentoraÂ® Restricted 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>FENTANYL‐>Tablets pain management team Approved for clopidogrel allergy/ intolerance only, in line with NICE EfientÂ® Restricted 2.9 Antiplatelet drugs‐>PRASUGREL guidance 13.9 Shampoos and other preparations for scalp and hair conditions‐ Restricted to dermatology and EFLORNITHINE Restricted >Hirsutism endocrinology only. 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines‐>DOXYCYCLINE‐ Approved for Dermatology for EfraceaÂ® Restricted >Modified‐release inflammatory facial rosacea 13.5 Preparations for eczema and psoriasis‐>13.5.3 Drugs affecting ElidelÂ® Restricted the immune response‐>PIMECROLIMUS Restricted to Dermatology only. 7.3 Contraceptives‐>7.3.5 Emergency contraception‐>Hormonal Restricted for Marlborough Clinic use ellaOneÂ® Restricted methods‐>ULIPRISTAL ACETATE only. Restricted to patients receiving cisplatin >/= 70mg/m2 or patients 4.6 Drugs used in nausea and vertigo‐>Neurokinin‐receptor with >/= grade 2 nausea and EmendÂ® Restricted antagonists‐>APREPITANT vomiting 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other EMPAGLIFLOZIN Restricted antidiabetic drugs

Prior funding approval required. Restricted to dermatology and rheumatology.Also approved for 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that TRAPS and HIDS (National suppress the rheumatic disease process‐>Cytokine modulators‐ Amyloidosis Centre)PCT funding EnbrelÂ® Restricted >ETANERCEPT approval required. NICE Restricted to use as per London HIV ENFUVIRTIDE Restricted 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Other antiretrovirals consortium guidelines.

For the treatment of acute coronary 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ syndrome only Low molecular weight ENOXAPARIN SODIUM Restricted >Low molecular weight heparins heparin protocol 13.6 Acne and rosacea‐>13.6.1 Topical preparations for acne‐>Topical retinoids and related preparations for acne‐>ADAPALENE‐>With Approved for Dermatology for acne EpiduoÂ® Restricted benzoyl peroxide vulgaris 2.2 Diuretics‐>2.2.3 Potassium‐sparing diuretics and aldosterone EPLERENONE Restricted antagonists‐>Aldosterone antagonists Restricted to Cardiology Restricted to ITU and pulmonary Epoprostenol Restricted 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants hypertension. 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ Restricted to ITU and pulmonary EPOPROSTENOL Restricted >Epoprostenol hypertension. Restricted to the Child & 4.4 CNS stimulants and drugs used for attention deficit hyperactivity Adolescent Mental Health Service Equasym XLÂ® Restricted disorder‐>METHYLPHENIDATE HYDROCHLORIDE‐>Modified release only. Prior funding approval required via Eribulin Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs CDF

ERIBULIN Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Eribulin Only available on Cancer Drugs Fund

Prior funding approval required. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase Restricted for treatment of non‐small ERLOTINIB Restricted inhibitors cell lung cancer only

5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and ERTAPENEM Restricted other beta‐lactams‐>5.1.2.2 Carbapenems Microbiology approval only. Restricted to ITU, cardiology and ESMOLOL HYDROCHLORIDE Restricted 2.4 Beta‐adrenoceptor blocking drugs theatre 8 only.

Prior funding approval required. 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that Restricted to dermatology and ETANERCEPT Restricted suppress the rheumatic disease process‐>Cytokine modulators rheumatology. NICE

Prior funding approval required via CDF for RCC and Breast Ca. Approved for pancreatic 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase NET as part of compassionate access EVEROLIMUS Restricted inhibitors program 9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in hypoplastic, haemolytic, and renal anaemias‐>Iron overload‐ ExjadeÂ® Restricted >DEFERASIROX Prior funding approval required 11.3 Anti‐infective eye preparations‐>11.3.1 Antibacterials‐ ExocinÂ® Restricted >OFLOXACIN Restricted to Opthalmologists only. Ezetimibe Restricted 2.12 Lipid‐regulating drugs Restricted to the lipid clinic. EZETIMIBE Restricted 2.12 Lipid‐regulating drugs‐>Ezetimibe Restricted to the lipid clinic. EzetrolÂ® Restricted 2.12 Lipid‐regulating drugs‐>Ezetimibe‐>EZETIMIBE Restricted to the lipid clinic. 5.1 Antibacterial drugs‐>5.1.11 Metronidazole and tinidazole‐ FasigynÂ® Restricted >TINIDAZOLE Microbiology/ID approval only.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

10.1 Drugs used in rheumatic diseases and gout‐>10.1.4 Gout and cytotoxic‐induced hyperuricaemia‐>Hyperuricaemia associated with FasturtecÂ® Restricted cytotoxic drugs‐>RASBURICASE Restricted to haematology.

9.1 Anaemias and some other blood disorders‐>9.1.1 Iron‐deficiency Restricted to Renal units and FerinjectÂ® Restricted anaemias‐>9.1.1.2 Parenteral iron‐>FERRIC CARBOXYMALTOSE gastroenterology only Ferric carboxymaltose Restricted Use of table‐>Table of drugs given by intravenous infusion Restricted to Renal Units only.

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ FEXOFENADINE HYDROCHLORIDE Restricted >3.4.1 Antihistamines‐>Non‐sedating antihistamines Restricted to dermatology only. 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.1 Antihistamines‐>Non‐sedating antihistamines‐>FEXOFENADINE Fexofenadine Hydrochloride Restricted HYDROCHLORIDE Restricted to dermatology only. 9.1 Anaemias and some other blood disorders‐>9.1.6 Drugs used in Restricted to hepatology out‐patients FILGRASTIM Restricted neutropenia only

8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐ FirmagonÂ® Restricted >Gonadotrophin‐releasing hormone antagonists‐>DEGARELIX Restricted to urology and Dr Pigott.

Accuhaler® and Diskhaler® formulations are restricted to Repiratory Medicine Consultants and FlixotideÂ® Restricted 3.2 Corticosteroids‐>FLUTICASONE Paediatricians. 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ Restricted to ITU and pulmonary FlolanÂ® Restricted >Epoprostenol‐>EPOPROSTENOL hypertension. 4.3 Antidepressant drugs‐>4.3.4 Other antidepressant drugs‐ Initiate after discussion with liaison FluanxolÂ® Restricted >FLUPENTIXOL psychiatry team.

INTRAVENOUS preparations restricted to Haematology; Oncology; HIV; Renal unit; Liver unit. Microbiology approval required for all FLUCONAZOLE Restricted 5.2 Antifungal drugs‐>5.2.1 Triazole antifungals other indications.

INTRAVENOUS preparations restricted to Haematology; Oncology; HIV; Renal unit; Liver unit. Microbiology approval required for all Fluconazole Restricted 5.2 Antifungal drugs‐>5.2.1 Triazole antifungals‐>FLUCONAZOLE other indications.

Restricted to HIV; Haematology; Oncology; Transplant patients. Microbiology approval required for all FLUCYTOSINE Restricted 5.2 Antifungal drugs‐>5.2.5 Other antifungals other indications.

FLUDROXYCORTIDE Restricted 13.4 Topical corticosteroids Restricted to Dermatologists only. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison FLUPENTIXOL Restricted Antipsychotic drugs‐>First‐generation antipsychotic drugs psychiatry team. Initiate after discussion with liaison FLUPENTIXOL Restricted 4.3 Antidepressant drugs‐>4.3.4 Other antidepressant drugs psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison FLUPENTIXOL DECANOATE Restricted Antipsychotic depot injections psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison FLUPHENAZINE DECANOATE Restricted Antipsychotic depot injections psychiatry team.

4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison Fluphenazine decanoate Restricted Antipsychotic depot injections‐>FLUPHENAZINE DECANOATE psychiatry team. FLUTICASONE PROPIONATE Restricted 13.4 Topical corticosteroids Restricted to paediatrics only. Restricted to liver and renal patients FLUVASTATIN Restricted 2.12 Lipid‐regulating drugs‐>Statins only.

Restricted ‐ only to be used under the Fondaparinux Restricted 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants advice of the haemophilia consultant

2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ Restricted ‐ only to be used under the FONDAPARINUX SODIUM Restricted >Fondaparinux advice of the haemophilia consultant 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Levodopa‐>CO‐ For use with enteral tube Restricted CARELDOPA Prior funding approval required. 6.6 Drugs affecting bone metabolism‐>6.6.1 Calcitonin and Restricted to Endocrinology and ForsteoÂ® Restricted parathyroid hormone‐>TERIPARATIDE Rheumatology use only Restricted to Haematology. 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and Microbiology approval required for all FortumÂ® Restricted other beta‐lactams‐>5.1.2.1 Cephalosporins‐>CEFTAZIDIME other indications. 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other ForxigaÂ® Restricted antidiabetic drugs‐>DAPAGLIFLOZIN Restricted to Endocrinology

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Restricted to HIV; Transplant patients; Haematology; Oncology. 5.3 Antiviral drugs‐>5.3.2 Herpesvirus infections‐>5.3.2.2 Virology approval required for all ther FOSCARNET SODIUM Restricted Cytomegalovirus infection indications.

Restricted to HIV; Transplant patients; Haematology; Oncology. 5.3 Antiviral drugs‐>5.3.2 Herpesvirus infections‐>5.3.2.2 Virology approval required for all ther FoscavirÂ® Restricted Cytomegalovirus infection‐>FOSCARNET SODIUM indications.

Oral capsules only. As a last line‐ salvage therapy for deep seated bone, vascular and organ space infections only on approval of an Infectious Diseases or Microbiology Fosfomycin Restricted 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials consultant 9.5 Minerals‐>9.5.2 Phosphorus‐>9.5.2.2 Phosphate‐binding agents‐ FosrenolÂ® Restricted >LANTHANUM Restricted to renal patients only.

Restricted to Dermatology 13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial Outpatients. Maximum prescription preparations‐>13.10.1.2 Antibacterial preparations also used for 14 days.Only the cream is FucidinÂ® Restricted systemically‐>FUSIDIC ACID available at The Royal Free Hospital. 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Other antiretrovirals‐ Restricted to use as per London HIV FuzeonÂ® Restricted >ENFUVIRTIDE consortium guidelines. Restricted to HIV; Haematology; Oncology; Liver and Renal Transplants; Other immunosuppressed patients. Virology 5.3 Antiviral drugs‐>5.3.2 Herpesvirus infections‐>5.3.2.2 approval required for all other GANCICLOVIR Restricted Cytomegalovirus infection indications. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase Approved for non small cell lung GEFITINIB Restricted inhibitors cancer

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ Requires funding approval prior to GenotropinÂ® Restricted >Anterior pituitary hormones‐>Growth hormone‐>SOMATROPIN prescribing. 8.2 Drugs affecting the immune response‐>8.2.4 Other Glatiramer acetate Restricted immunomodulating drugs Prior funding approval required 8.2 Drugs affecting the immune response‐>8.2.4 Other GLATIRAMER ACETATE Restricted immunomodulating drugs‐>Glatiramer acetate Prior funding approval required GliadelÂ® Restricted 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs‐>CARMUSTINE Restricted to Neurosurgery 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.1 Glipizide Restricted Sulfonylureas‐>GLIPIZIDE Restriceted to the diabetes team.

Prior funding approval requiredAlso 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase approved for Ph + all. Division to fund GlivecÂ® Restricted inhibitors‐>IMATINIB for this indication. 1.5 Chronic bowel disorders‐>1.5.3 Drugs affecting the immune GOLIMUMAB Restricted response‐>Cytokine modulators Restricted to rheumatology

Gonadotrophin‐releasing hormone 8.3 Sex hormones and hormone antagonists in malignant disease‐ antagonists Restricted >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer Restricted to urology and Dr Pigott. 6.7 Other endocrine drugs‐>6.7.2 Drugs affecting gonadotrophins‐ Approved for Paediatrics for central Gonapeptyl DepotÂ® Restricted >Gonadorelin analogues‐>TRIPTORELIN precocious puberty

HaelanÂ® Restricted 13.4 Topical corticosteroids‐>FLUDROXYCORTIDE Restricted to Dermatologists only. 4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison Haldol DecanoateÂ® Restricted Antipsychotic depot injections‐>HALOPERIDOL psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>First‐generation antipsychotic drugs‐ Initiate after discussion with liaison HaldolÂ® Restricted >HALOPERIDOL psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>First‐generation antipsychotic drugs‐ Initiate after discussion with liaison Haloperidol Restricted >HALOPERIDOL psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison HALOPERIDOL Restricted Antipsychotic depot injections psychiatry team. See protocol for indications. Heparinoids Restricted 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants Danaparoid protocol 5.3 Antiviral drugs‐>5.3.3 Viral hepatitis‐>5.3.3.1 Chronic hepatitis B‐ HepseraÂ® Restricted >ADEFOVIR DIPIVOXIL Restricted to Hepatology/Virology.

Prior funding approval required. Approved for breast cancer and 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Trastuzumab‐ adenocarcinoma of the stomach in HerceptinÂ® Restricted >TRASTUZUMAB line with NICE guidance. Cleared for A+E..Available for use at 13.10 Anti‐infective skin preparations‐>13.10.5 Preparations for Queen Mary's house..Restricted HistoacrylÂ® Restricted minor cuts and abrasions‐>Skin tissue adhesive prescribing.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Prior funding approval required. Restricted to dermatology, 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that gastroenterology, paediatric suppress the rheumatic disease process‐>Cytokine modulators‐ gastroenterology and rheumatology. HumiraÂ® Restricted >ADALIMUMAB NICE Approved for the treatment of relapsed small‐call lung cancer as per NICE guidance. Prior funding approval required. NICE guidance for the 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐ treatment of replased small‐cell lung HycamtinÂ® Restricted >Topoisomerase I inhibitors‐>TOPOTECAN cancer 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase IBRUTINIB Restricted inhibitors 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase IclusigÂ® Restricted inhibitors‐>PONATINIB

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Restricted to cardiologist prescribing IkorelÂ® Restricted >2.6.3 Other antianginal drugs‐>NICORANDIL only.

8.2 Drugs affecting the immune response‐>8.2.4 Other Prior funding approval required. IlarisÂ® Restricted immunomodulating drugs‐>Canakinumab‐>CANAKINUMAB Approved for Professor Hawkins 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator ILOPROST Restricted antihypertensive drugs For ITU use only. Notification only for CML indication 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase Also approved for Ph + ALL (NHSE IMATINIB Restricted inhibitors funded) Sumatriptan is restricted to neurologists and is for in‐patient 4.7 Analgesics‐>4.7.4 Antimigraine drugs‐>4.7.4.1 Treatment of acute prescribing only.The nasal spray is ImigranÂ® Restricted migraine‐>5HT1‐receptor agonists‐>SUMATRIPTAN NOT formulary.

5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and IMIPENEM WITH CILASTATIN Restricted other beta‐lactams‐>5.1.2.2 Carbapenems Microbiology approval only. 2.5 Hypertension and heart failure‐>2.5.4 Alpha‐adrenoceptor Restricted to urology only. Only 20mg INDORAMIN Restricted blocking drugs tablets kept at the RFH. 7.4 Drugs for genito‐urinary disorders‐>7.4.1 Drugs for urinary INDORAMIN Restricted retention‐>Alpha‐blockers Restricted to urologist only.

Prior funding approval required. Restricted to dermatology, gastroenterology, immunology, neurology (and neurosarcoid) , 1.5 Chronic bowel disorders‐>1.5.3 Drugs affecting the immune paediatric gastroenterology and INFLIXIMAB Restricted response‐>Cytokine modulators rheumatology.

Prior funding approval required. Restricted to dermatology, gastroenterology, immunology, 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that neurology, paediatric INFLIXIMAB Restricted suppress the rheumatic disease process‐>Cytokine modulators gastroenterology and rheumatology.

2.2 Diuretics‐>2.2.3 Potassium‐sparing diuretics and aldosterone InspraÂ® Restricted antagonists‐>Aldosterone antagonists‐>EPLERENONE Restricted to Cardiology

8.2 Drugs affecting the immune response‐>8.2.4 Other Interferon beta‐1a Restricted immunomodulating drugs‐>Interferon beta‐>INTERFERON BETA Prior funding approval required

8.2 Drugs affecting the immune response‐>8.2.4 Other Interferon beta‐1b Restricted immunomodulating drugs‐>Interferon beta‐>INTERFERON BETA Prior funding approval required 8.2 Drugs affecting the immune response‐>8.2.4 Other Interferon gamma Restricted immunomodulating drugs Restricted to immunology use only 8.2 Drugs affecting the immune response‐>8.2.4 Other INTERFERON GAMMA‐1b Restricted immunomodulating drugs‐>Interferon gamma Restricted to immunology use only

5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and InvanzÂ® Restricted other beta‐lactams‐>5.1.2.2 Carbapenems‐>ERTAPENEM Microbiology approval only. 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other InvokanaÂ® Restricted antidiabetic drugs‐>CANAGLIFLOZIN Restricted to Endocrinology

11.8 Miscellaneous ophthalmic preparations‐>11.8.2 Ocular diagnostic and peri‐operative preparations and photodynamic IopidineÂ® Restricted treatment‐>Ocular peri‐operative drugs‐>APRACLONIDINE 1% restricted to Opthalmology.

2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ IRBESARTAN Restricted angiotensin system‐>2.5.5.2 Angiotensin‐II receptor antagonists Restricted to renal patients only.

8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase Approved for non small cell lung IressaÂ® Restricted inhibitors‐>GEFITINIB cancer, PCT funding required.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Other antiretrovirals‐ Restricted to use as per London HIV IsentressÂ® Restricted >RALTEGRAVIR consortium guidelines.

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Restricted to cardiac cath lab use IsoketÂ® Restricted >2.6.1 Nitrates‐>ISOSORBIDE DINITRATE‐>Parenteral preparations only.

ORAL preparations restricted to Dermatology; HIV; Haematology; Marlborough OPD.INTRAVENOUS preparations restricted to Haematology. Microbiology approval ITRACONAZOLE Restricted 5.2 Antifungal drugs‐>5.2.1 Triazole antifungals required for all other indications. 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other Restricted to initiation by JanuviaÂ® Restricted antidiabetic drugs‐>SITAGLIPTIN endocrinology only 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Trastuzumab Prior funding approval required via KadcylaÂ® Restricted emtansine‐>TRASTUZUMAB EMTANSINE CDF Restricted to Haematology. 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and Microbiology approval required for all KefadimÂ® Restricted other beta‐lactams‐>5.1.2.1 Cephalosporins‐>CEFTAZIDIME other indications. 13.9 Shampoos and other preparations for scalp and hair conditions‐ Restricted to Dermatology Ketoconazole Restricted >Shampoos Outpatients only. 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal Restricted to Dermatology KETOCONAZOLE Restricted preparations Outpatients only. 15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ KETOROLAC TROMETAMOL Restricted operative drugs‐>15.1.4.2 Non‐opioid analgesics Restricted to anaesthetists.

Prior funding approval required. 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that Restricted to use by the Amyloidosis suppress the rheumatic disease process‐>Cytokine modulators‐ centre only.Not approved for use in KineretÂ® Restricted >ANAKINRA rheumatoid arthritis. 4.6 Drugs used in nausea and vertigo‐>Hyoscine‐>HYOSCINE KwellsÂ® Restricted HYDROBROMIDE Restricted to Psychiatry Restricted to neurology as second Lacosamide Restricted 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies line therapy. Restricted to neurology as second LACOSAMIDE Restricted 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Lacosamide line therapy. 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal Approved only for dermatology LamisilÂ® Restricted preparations‐>TERBINAFINE patients.

8.3 Sex hormones and hormone antagonists in malignant disease‐ RESTRICTED TO ENDOCRINE AND LANREOTIDE Restricted >8.3.4 Hormone antagonists‐>8.3.4.3 Somatostatin analogues LIVER UNITS

LANTHANUM Restricted 9.5 Minerals‐>9.5.2 Phosphorus‐>9.5.2.2 Phosphate‐binding agents Restricted to renal patients only. Initiation of therapy under the 6.1 Drugs used in diabetes‐>6.1.1 Insulins‐>6.1.1.2 Intermediate‐ and recommendation of the diabetic LantusÂ® Restricted long‐acting insulins‐>INSULIN GLARGINE team only.

8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase Approved for breast cancer. Prior LAPATINIB Restricted inhibitors funding approval required. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>First‐generation antipsychotic drugs‐ Initiate after discussion with liaison LargactilÂ® Restricted >CHLORPROMAZINE HYDROCHLORIDE psychiatry team. 11.6 Treatment of glaucoma‐>Prostaglandin analogues and LATANOPROST Restricted prostamides Restricted to Opthalmologists only. 8.2 Drugs affecting the immune response‐>8.2.4 Other immunomodulating drugs‐>Lenalidomide, pomalidomide, and LENALIDOMIDE Restricted thalidomide Prior funding approval required Restricted to liver and renal patients LescolÂ® Restricted 2.12 Lipid‐regulating drugs‐>Statins‐>FLUVASTATIN only. Restricted to liver and renal patients LescolÂ® XL Restricted 2.12 Lipid‐regulating drugs‐>Statins‐>FLUVASTATIN‐>Modified release only. 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Gonadorelin Restricted to gynaecology only. See LEUPRORELIN ACETATE Restricted analogues section 6.7.2 8.1 Cytotoxic drugs‐>8.1.1 Alkylating drugs‐>BENDAMUSTINE Approved for Haematology for NHL, LevactÂ® Restricted HYDROCHLORIDE PCT funding required.

Restricted to community acquired pneumonia patients with beta‐lactam allergy. Microbiology approval LEVOFLOXACIN Restricted 5.1 Antibacterial drugs‐>5.1.12 Quinolones required for all other indications. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison LEVOMEPROMAZINE Restricted Antipsychotic drugs‐>First‐generation antipsychotic drugs psychiatry team.

4.2 Drugs used in psychoses and related disorders‐>4.2.3 Drugs used Initiate after discussion with liaison Li‐LiquidÂ® Restricted for mania and hypomania‐>Lithium‐>LITHIUM CITRATE psychiatry team. Linezolid Restricted 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials Microbiology approval only.

LINEZOLID Restricted 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐>Linezolid Microbiology approval only.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

LIOTHYRONINE SODIUM Restricted 6.2 Thyroid and antithyroid drugs‐>6.2.1 Thyroid hormones Restricted ‐ IV only on formulary. 6.2 Thyroid and antithyroid drugs‐>6.2.1 Thyroid hormones‐ Liothyronine sodium Restricted >LIOTHYRONINE SODIUM Restricted ‐ IV only on formulary. Use is restricted to HIV, Renal, and lipid clinic patients, as well as suspected simvastatin intolerance and drug interactions. Statin LipitorÂ® Restricted 2.12 Lipid‐regulating drugs‐>Statins‐>ATORVASTATIN prescribing 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other LIRAGLUTIDE Restricted antidiabetic drugs Restricted to endocrinology. 4.2 Drugs used in psychoses and related disorders‐>4.2.3 Drugs used Initiate after discussion with liaison Lithium Restricted for mania and hypomania psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.3 Drugs used Initiate after discussion with liaison LITHIUM CARBONATE Restricted for mania and hypomania‐>Lithium psychiatry team. 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ Restricted to gynaecology and the LivialÂ® Restricted >6.4.1.1 Oestrogens and HRT‐>TIBOLONE menopause clinic only.

Restricted antimicrobial agentOnly 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal the nail lacquer is available at The LocerylÂ® Restricted preparations‐>AMOROLFINE Royal Free Hospital.

11.8 Miscellaneous ophthalmic preparations‐>11.8.2 Ocular diagnostic and peri‐operative preparations and photodynamic Prior funding approval required. LucentisÂ® Restricted treatment‐>Subfoveal choroidal neovascularisation‐>RANIBIZUMAB Restricted to Opthalmology.

Prior funding approval required for treatment of pemphigus, SLE, RA and C2 deficient lupus erythematosus. Approved for treatment of lymphoma, CLL, ITP, AIHA, EBV, Waldenstrom's macroglobulinaemia, Castleman's disease (1st line), acquired and congenital coagulation inhibitors and maintenance treatment of follicular lymphoma. 8.2 Drugs affecting the immune response‐>8.2.3 Anti‐lymphocyte Notification only for renal vasculitis MabTheraÂ® Restricted monoclonal antibodies‐>RITUXIMAB and SLE patients. 4.3 Antidepressant drugs‐>4.3.2 Monoamine‐oxidase inhibitors‐ Initiate after discussion with liaison ManerixÂ® Restricted >Reversible MAOIs‐>MOCLOBEMIDE psychiatry team. Restricted to use as per London HIV MARAVIROC Restricted 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Other antiretrovirals consortium guidelines.

MEMANTINE HYDROCHLORIDE Restricted 4.11 Dementia Mental Health Trust Formulary Only. Restricted to Neurosurgical meningitis; Haematology. 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and Microbiology approval required for all MeronemÂ® Restricted other beta‐lactams‐>5.1.2.2 Carbapenems‐>MEROPENEM other indications. Restricted to Neurosurgical meningitis; Haematology. 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and Microbiology approval required for all MEROPENEM Restricted other beta‐lactams‐>5.1.2.2 Carbapenems other indications. 2.10 Stable angina, acute coronary syndromes, and fibrinolysis‐ MetalyseÂ® Restricted >2.10.2 Fibrinolytic drugs‐>TENECTEPLASE Restricted to cardiology only. 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Drugs affecting the immune 10mg tablets restricted for METHOTREXATE Restricted response haematology only 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Drugs affecting the immune 10mg tablets restricted for Methotrexate Restricted response‐>METHOTREXATE haematology only

METHOXY POLYETHYLENE GLYCOL‐EPOETIN 9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in BETA Restricted hypoplastic, haemolytic, and renal anaemias‐>Erythropoietins Restricted to renal team only. Restricted to the Child & 4.4 CNS stimulants and drugs used for attention deficit hyperactivity Adolescent Mental Health Service METHYLPHENIDATE HYDROCHLORIDE Restricted disorder only. Restricted to the Child & 4.4 CNS stimulants and drugs used for attention deficit hyperactivity Adolescent Mental Health Service Methylphenidate Hydrochloride Restricted disorder‐>METHYLPHENIDATE HYDROCHLORIDE only. 13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial preparations‐>13.10.1.2 Antibacterial preparations also used Restricted for the treatment of MetrogelÂ® Restricted systemically‐>METRONIDAZOLE rosacea only. 13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial preparations‐>13.10.1.2 Antibacterial preparations also used Restricted for the treatment of MetrosaÂ® Restricted systemically‐>METRONIDAZOLE rosacea only.

MifegyneÂ® Restricted 7.1 Drugs used in obstetrics‐>7.1.2 Mifepristone‐>MIFEPRISTONE Restricted to gynaecologist only

MIFEPRISTONE Restricted 7.1 Drugs used in obstetrics‐>7.1.2 Mifepristone Restricted to gynaecologist only

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Under Professor Cunningham's 9.5 Minerals‐>9.5.1 Calcium and magnesium‐>9.5.1.2 Hypercalcaemia recommendation and approved for MimparaÂ® Restricted and hypercalciuria‐>CINACALCET endocrinology. Restricted to Dermatology; Marlborough OPD. Microbiology approval required for all other MINOCYCLINE Restricted 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines indications. Restricted to Dermatology; Marlborough OPD. Microbiology approval required for all other Minocycline Restricted 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines‐>MINOCYCLINE indications.

Restricted to Dermatologists.Only the 13.9 Shampoos and other preparations for scalp and hair conditions‐ extra strength minoxidil 5% is kept at MINOXIDIL Restricted >Androgenetic alopecia The Royal Free Hospital.

9.1 Anaemias and some other blood disorders‐>9.1.3 Drugs used in hypoplastic, haemolytic, and renal anaemias‐>Erythropoietins‐ MirceraÂ® Restricted >METHOXY POLYETHYLENE GLYCOL‐EPOETIN BETA Restricted to renal team only 4.3 Antidepressant drugs‐>4.3.2 Monoamine‐oxidase inhibitors‐ Initiate after discussion with liaison MOCLOBEMIDE Restricted >Reversible MAOIs psychiatry team. 4.3 Antidepressant drugs‐>4.3.2 Monoamine‐oxidase inhibitors‐ Initiate after discussion with liaison Moclobemide Restricted >Reversible MAOIs‐>MOCLOBEMIDE psychiatry team.

4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison Modecate ConcentrateÂ® Restricted Antipsychotic depot injections‐>FLUPHENAZINE DECANOATE psychiatry team.

4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison ModecateÂ® Restricted Antipsychotic depot injections‐>FLUPHENAZINE DECANOATE psychiatry team.

Modified release Restricted 2.12 Lipid‐regulating drugs‐>Nicotinic acid group‐>NICOTINIC ACID Restricted to the lipid clinic only. Restricted to the Child & 4.4 CNS stimulants and drugs used for attention deficit hyperactivity Adolescent Mental Health Service Modified release Restricted disorder‐>METHYLPHENIDATE HYDROCHLORIDE only.

Restricted to individual patients 8.2 Drugs affecting the immune response‐>8.2.2 Corticosteroids and identified by the renal and liver Modified release Restricted other immunosuppressants‐>TACROLIMUS transplantation teams only.

MOMETASONE FUROATE Restricted 3.2 Corticosteroids Restricted to Thoracic Medicine only.

Restricted to thoracic medicine. ID/Microbiology approval required MOXIFLOXACIN Restricted 5.1 Antibacterial drugs‐>5.1.12 Quinolones for all other indications. 9.1 Anaemias and some other blood disorders‐>9.1.7 Drugs used to MozobilÂ® Restricted mobilise stem cells‐>PLERIXAFOR Restricted to BMT only.

Restricted to Dermatology outpatients for impetigo only. Maximum 14 days prescription.Only 13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial the ointment is kept at The Royal preparations‐>13.10.1.1 Antibacterial preparations only used Free Hospital.See Section 12.2.3 for MUPIROCIN Restricted topically Mupirocin Nasal Ointment.

MycobutinÂ® Restricted 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs‐>RIFABUTIN ID/Microbiology approval only. 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Restricted to rheumatology and NABUMETONE Restricted steroidal anti‐inflammatory drugs haematology. 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Restricted to rheumatology and Nabumetone Restricted steroidal anti‐inflammatory drugs‐>NABUMETONE haematology. 1.5 Chronic bowel disorders‐>1.5.4 Food allergy‐>SODIUM NalcromÂ® Restricted CROMOGLICATE Restricted to the allergy clinic

8.2 Drugs affecting the immune response‐>8.2.4 Other Prior funding approval required. Natalizumab Restricted immunomodulating drugs Restricted to Neurology patients.

8.2 Drugs affecting the immune response‐>8.2.4 Other Prior funding approval required. NATALIZUMAB Restricted immunomodulating drugs‐>Natalizumab Restricted to Neurology patients. 3.3 Cromoglicate and related therapy, leukotriene receptor antagonists, and phosphodiesterase type‐4 inhibitors‐>3.3.1 NEDOCROMIL SODIUM Restricted Cromoglicate and related therapy Restricted to Paediatrics only. 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.2 Penicillinase‐ NegabanÂ® Restricted resistant penicillins‐>TEMOCILLIN Microbiology approval required. NELARABINE Restricted 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites 9.1 Anaemias and some other blood disorders‐>9.1.6 Drugs used in Drug & Therapeutics Committee NeulastaÂ® Restricted neutropenia‐>PEGFILGRASTIM approval required 9.1 Anaemias and some other blood disorders‐>9.1.6 Drugs used in Restricted to hepatology out‐patients NeupogenÂ® Restricted neutropenia‐>FILGRASTIM only

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Restricted to peri‐operative 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Parkinson's patients Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor only.6mg/24hour and 8mg/24hour NeuproÂ® Restricted agonists‐>ROTIGOTINE patches are not kept 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase NexavarÂ® Restricted inhibitors‐>SORAFENIB Prior funding approval required 2.12 Lipid‐regulating drugs‐>Nicotinic acid group‐>NICOTINIC ACID‐ NiaspanÂ® Restricted >Modified release Restricted to the lipid clinic only.

NICOTINIC ACID Restricted 2.12 Lipid‐regulating drugs‐>Nicotinic acid group Restricted to the lipid clinic only. NOT SURE WHERE THIS IS ORDERED Nitrous oxide Restricted 15.1 General anaesthesia‐>15.1.2 Inhalational anaesthetics FROM?????? Nivolumab Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal Restricted to Dermatology NizoralÂ® Restricted preparations‐>KETOCONAZOLE Outpatients only. 4.3 Antidepressant drugs‐>4.3.1 Tricyclic and related antidepressant Initiate after discussion with liaison NORTRIPTYLINE Restricted drugs‐>Tricyclic antidepressants psychiatry team. Restricted to Haematology. Microbiology approval required for all NoxafilÂ® Restricted 5.2 Antifungal drugs‐>5.2.1 Triazole antifungals‐>POSACONAZOLE other indications. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>First‐generation antipsychotic drugs‐ Initiate after discussion with liaison NozinanÂ® Restricted >LEVOMEPROMAZINE psychiatry team.

9.1 Anaemias and some other blood disorders‐>9.1.4 Drugs used in Approved as 6th line for refractory platelet disorders‐>Idiopathic thrombocytopenic purpura‐ ITP, treatment algorithm available. NplateÂ® Restricted >ROMIPLOSTIM Funding approval required.

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ Requires funding approval prior to NutropinAqÂ® Restricted >Anterior pituitary hormones‐>Growth hormone‐>SOMATROPIN prescribing. 8.2 Drugs affecting the immune response‐>8.2.3 Anti‐lymphocyte OBINUTUZUMAB Restricted monoclonal antibodies

6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ Restricted to the menopause clinic OestrogelÂ® Restricted >6.4.1.1 Oestrogens and HRT‐>OESTROGENS FOR HRT‐>Estradiol only only. 8.2 Drugs affecting the immune response‐>8.2.3 Anti‐lymphocyte OFATUMUMAB Restricted monoclonal antibodies OFLOXACIN Restricted 5.1 Antibacterial drugs‐>5.1.12 Quinolones ID/Microbiology approval only. Ofloxacin Restricted 5.1 Antibacterial drugs‐>5.1.12 Quinolones‐>OFLOXACIN ID/Microbiology approval only.

OFLOXACIN Restricted 11.3 Anti‐infective eye preparations‐>11.3.1 Antibacterials Restricted to Opthalmologists only.

13.2 Emollient and barrier preparations‐>13.2.1 Emollients‐>13.2.1.1 OilatumÂ® Plus Restricted Emollient bath and shower preparations‐>With antimicrobials Restricted to Dermatologists only.

4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison OLANZAPINE Restricted Antipsychotic drugs‐>Second‐generation antipsychotic drugs psychiatry team. 2.12 Lipid‐regulating drugs‐>Omega‐3 fatty acid compounds‐>OMEGA‐Restricted to HIV and lipid clinic OmacorÂ® Restricted 3‐ACID ETHYL ESTERS patients only. 3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ Restricted to respiratory consultant Omalizumab Restricted >3.4.2 Allergen immunotherapy prescribing only Restricted to HIV and lipid clinic OMEGA‐3‐ACID ETHYL ESTERS Restricted 2.12 Lipid‐regulating drugs‐>Omega‐3 fatty acid compounds patients only.

Once‐daily preparations Restricted 11.6 Treatment of glaucoma‐>Beta‐blockers‐>TIMOLOL Restricted to Opthalmologists only.

Restricted to Oncologists, Haematologists, HIV and Paediatricians.Used 2nd line for post‐ operative nausea and vomiting.The Oral Lyophilisates are not kept at The ONDANSETRON Restricted 4.6 Drugs used in nausea and vertigo‐>5HT3‐receptor antagonists Royal Free Hospital.

Restricted to Oncologists, Haematologists, HIV and Paediatricians.Used 2nd line for post‐ operative nausea and vomiting.The 4.6 Drugs used in nausea and vertigo‐>5HT3‐receptor antagonists‐ Oral Lyophilisates are not kept at The Ondansetron Restricted >ONDANSETRON Royal Free Hospital.

10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that Approved for rheumatoid arthritis,in suppress the rheumatic disease process‐>Cytokine modulators‐ line with NICE guidance. PCT funding OrenciaÂ® Restricted >ABATACEPT approval required 2.8 Anticoagulants and protamine‐>2.8.1 Parenteral anticoagulants‐ See protocol for indications. OrgaranÂ® Restricted >Heparinoids‐>DANAPAROID SODIUM Danaparoid protocol 4.5 Obesity‐>4.5.1 Anti‐obesity drugs acting on the gastro‐intestinal ORLISTAT Restricted tract Restricted to the Lipid Clinic Only.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Virology/Microbiology/ID approval OSELTAMIVIR Restricted 5.3 Antiviral drugs‐>5.3.4 Influenza only. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase OSIMERTINIB Restricted inhibitors Other drugs for reversal of neuromuscular 15.1 General anaesthesia‐>15.1.6 Drugs for reversal of neuromuscular blockade Restricted blockade Restricted to Theatres

8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Platinum Restricted for treatment of colorectal OXALIPLATIN Restricted compounds and oesophago‐gastric cancers only

8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Platinum Restricted for treatment of colorectal Oxaliplatin Restricted compounds‐>OXALIPLATIN and oesophago‐gastric cancers only 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ OXCARBAZEPINE Restricted >Carbamazepine and related antiepileptics Restricted to neurology only.

Restricted for treatment of breast PACLITAXEL Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Taxanes cancer and Kaposi's sarcoma

8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Taxanes‐ Restricted for treatment of breast Paclitaxel Restricted >PACLITAXEL cancer and Kaposi's sarcoma PALIVIZUMAB Restricted 5.3 Antiviral drugs‐>5.3.5 Respiratory syncytial virus Restricted to Neonatology. Prior funding approval required vai Panitumumab Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs CDF Panobinostat Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs 2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ Restricted to cardiac cath lab use Parenteral preparations Restricted >2.6.1 Nitrates‐>ISOSORBIDE DINITRATE only. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase Approved for metastatic renal cell PAZOPANIB Restricted inhibitors carcinoma only

8.2 Drugs affecting the immune response‐>8.2.4 Other Prior funding approval required. PegasysÂ® Restricted immunomodulating drugs‐>Interferon alfa‐>PEGINTERFERON ALFA Restricted to hepatology only. 9.1 Anaemias and some other blood disorders‐>9.1.6 Drugs used in Drug & Therapeutics Committee PEGFILGRASTIM Restricted neutropenia approval required

8.2 Drugs affecting the immune response‐>8.2.4 Other Prior funding approval required. PEGINTERFERON ALFA Restricted immunomodulating drugs‐>Interferon alfa Restricted to hepatology only. Pembrolizumab Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs

Prior funding approval required. Restricted for the treatment of mesothelioma and non‐small cell lung cancer in combination with cisplatin only, as per NICE guidance.Approved for non small lung cancer in line with NICE guidance. PCT funding approval PEMETREXED Restricted 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites required. 5.4 Antiprotozoal drugs‐>5.4.8 Drugs for pneumocystis pneumonia‐ PentacarinatÂ® Restricted >PENTAMIDINE ISETIONATE ID/Microbiology approval only.

PENTAMIDINE ISETIONATE Restricted 5.4 Antiprotozoal drugs‐>5.4.8 Drugs for pneumocystis pneumonia ID/Microbiology approval only. 5.4 Antiprotozoal drugs‐>5.4.5 Leishmaniacides‐>SODIUM PentostamÂ® Restricted STIBOGLUCONATE Restricted to ID/Microbiology. Restricted to Dr Liu and Dr Angus‐ PERAMPANEL Restricted 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Perampanel Leppan

Restricted to Theatres and ITU, A and E.Use on wards needs pain team approval.Approved for short term treatment of pain in patients who are nil by mouth and only iv is indicated. 4.7 Analgesics‐>4.7.1 Non‐opioid analgesics and compound analgesic RFH Guidelines for Use of IV PerfalganÂ® Restricted preparations‐>PARACETAMOL Paracetamol Pertuzumab Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs 9.5 Minerals‐>9.5.2 Phosphorus‐>9.5.2.2 Phosphate‐binding agents‐ PhosexÂ® Restricted >CALCIUM SALTS Restricted to renal patients only.

Restricted to Urology, Endocrinology, 7.4 Drugs for genito‐urinary disorders‐>7.4.5 Drugs for erectile Pulmonary Hypertension, and Phosphodiesterase type‐5 inhibitors Restricted dysfunction Rheumatology only 13.5 Preparations for eczema and psoriasis‐>13.5.3 Drugs affecting PIMECROLIMUS Restricted the immune response Restricted to Dermatology only.

PIVMECILLINAM HYDROCHLORIDE Restricted 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.5 Mecillinams Microbiology approval required. 9.1 Anaemias and some other blood disorders‐>9.1.7 Drugs used to PLERIXAFOR Restricted mobilise stem cells Restricted to BMT only. 8.2 Drugs affecting the immune response‐>8.2.4 Other immunomodulating drugs‐>Lenalidomide, pomalidomide, and POMALIDOMIDE Restricted thalidomide

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase Prior funding approval required via PONATINIB Restricted inhibitors CDF 3.5 Respiratory stimulants and pulmonary surfactants‐>3.5.2 PORACTANT ALFA Restricted Pulmonary surfactants Restricted to The Neonatal Unit. Restricted to Haematology. Microbiology approval required for all POSACONAZOLE Restricted 5.2 Antifungal drugs‐>5.2.1 Triazole antifungals other indications. Approved for clopidogrel intolerance / allergy only, in line with NICE PRASUGREL Restricted 2.9 Antiplatelet drugs guidance

Prior funding approval required. Restricted to dermatology, 1.5 Chronic bowel disorders‐>1.5.3 Drugs affecting the immune gastroenterology, paediatric Preparations Restricted response‐>Cytokine modulators‐>ADALIMUMAB gastroenterology and rheumatology.

Prior funding approval required. Restricted to dermatology, gastroenterology, immunology, 1.5 Chronic bowel disorders‐>1.5.3 Drugs affecting the immune neurology, paediatric Preparations Restricted response‐>Cytokine modulators‐>INFLIXIMAB gastroenterology and rheumatology. Preparations Restricted 5.4 Antiprotozoal drugs‐>5.4.2 Amoebicides‐>TINIDAZOLE Microbiology/ID approval only.

Prior funding approval required for 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that rheumatology only. Restricted to suppress the rheumatic disease process‐>Cytokine modulators‐ haematology, nephrology and Preparations Restricted >RITUXIMAB rheumatology. NICE guidance 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors‐ Restricted to use as per London HIV PrezistaÂ® Restricted >DARUNAVIR consortium guidelines.

4.2 Drugs used in psychoses and related disorders‐>4.2.3 Drugs used Initiate after discussion with liaison PriadelÂ® Restricted for mania and hypomania‐>Lithium‐>LITHIUM CITRATE psychiatry team. 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and other beta‐lactams‐>5.1.2.2 Carbapenems‐>IMIPENEM WITH PrimaxinÂ® Restricted CILASTATIN Microbiology approval only. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison PROCHLORPERAZINE Restricted Antipsychotic drugs‐>First‐generation antipsychotic drugs psychiatry team.

6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and Approved for osteoporosis treatment ProliaÂ® Restricted other drugs affecting bone metabolism‐>Denosumab‐>DENOSUMAB by Endocrinology, Rheumatology 2.3 Anti‐arrhythmic drugs‐>2.3.2 Drugs for arrhythmias‐ PROPAFENONE HYDROCHLORIDE Restricted >Supraventricular and ventricular arrhythmias Restricted to cardiology only. 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Gonadorelin Restricted to gynaecology only. See ProstapÂ® 3 DCS Restricted analogues‐>LEUPRORELIN ACETATE section 6.7.2 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.2 Prostate Cancer‐>Gonadorelin Restricted to gynaecology only. See ProstapÂ® SR DCS Restricted analogues‐>LEUPRORELIN ACETATE section 6.7.2 Protein kinase inhibitors Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs 6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and other drugs affecting bone metabolism‐>Strontium ranelate‐ Restricted to 2nd line use as per NICE ProtelosÂ® Restricted >STRONTIUM RANELATE guidance 13.5 Preparations for eczema and psoriasis‐>13.5.3 Drugs affecting ProtopicÂ® Restricted the immune response‐>TACROLIMUS Restricted to Dermatology only.

Approved for women with chronic constipation as third‐line drug, in line PRUCALOPRIDE Restricted 1.6 Laxatives‐>1.6.7 Other drugs used in constipation with NICE guidance PYRAZINAMIDE Restricted 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs Restricted to TB treatment.

4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison QUETIAPINE Restricted Antipsychotic drugs‐>Second‐generation antipsychotic drugs psychiatry team. 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme Restricted to scleroderma patients QUINAPRIL Restricted inhibitors only. 2.5 Hypertension and heart failure‐>2.5.5 Drugs affecting the renin‐ angiotensin system‐>2.5.5.1 Angiotensin‐converting enzyme Restricted to scleroderma patients Quinapril Restricted inhibitors‐>QUINAPRIL only. Restricted to use as per London HIV RALTEGRAVIR Restricted 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Other antiretrovirals consortium guidelines.

11.8 Miscellaneous ophthalmic preparations‐>11.8.2 Ocular diagnostic and peri‐operative preparations and photodynamic Prior funding approval required. RANIBIZUMAB Restricted treatment‐>Subfoveal choroidal neovascularisation Restricted to Opthalmology.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

10.1 Drugs used in rheumatic diseases and gout‐>10.1.4 Gout and cytotoxic‐induced hyperuricaemia‐>Hyperuricaemia associated with RASBURICASE Restricted cytotoxic drugs Restricted to haematology. 8.2 Drugs affecting the immune response‐>8.2.4 Other immunomodulating drugs‐>Interferon beta‐>INTERFERON BETA‐ RebifÂ® Restricted >Interferon beta‐1a Prior funding approval required

Restricted to Dermatologists.Only the 13.9 Shampoos and other preparations for scalp and hair conditions‐ extra strength minoxidil 5% is kept at RegaineÂ® Restricted >Androgenetic alopecia‐>MINOXIDIL The Royal Free Hospital. Virology/Microbiology/ID approval RelenzaÂ® Restricted 5.3 Antiviral drugs‐>5.3.4 Influenza‐>ZANAMIVIR only. 10.1 Drugs used in rheumatic diseases and gout‐>10.1.1 Non‐ Restricted to rheumatology and RelifexÂ® Restricted steroidal anti‐inflammatory drugs‐>NABUMETONE haematology.

Prior funding approval required. Restricted to dermatology, gastroenterology, immunology, neurology, paediatric 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that gastroenterology and rheumatology. suppress the rheumatic disease process‐>Cytokine modulators‐ Approved for psoriatic arthritis Apr RemicadeÂ® Restricted >INFLIXIMAB 2011 15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ REMIFENTANIL Restricted operative drugs‐>15.1.4.3 Opioid analgesics 9.5 Minerals‐>9.5.2 Phosphorus‐>9.5.2.2 Phosphate‐binding agents‐ RenagelÂ® Restricted >SEVELAMER HYDROCHLORIDE Restricted to renal patients only. Restricted to use in the cardiology ReoProÂ® Restricted 2.9 Antiplatelet drugs‐>ABCIXIMAB cath lab only.

Approved for women with chronic 1.6 Laxatives‐>1.6.7 Other drugs used in constipation‐ constipation as third line drug, in line ResolorÂ® Restricted >PRUCALOPRIDE with NICE guidance.

Prior funding approval required. 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator Restricted to the treatment of RevatioÂ® Restricted antihypertensive drugs‐>SILDENAFIL pulmonary hypertension.

7.4 Drugs for genito‐urinary disorders‐>7.4.5 Drugs for erectile Restricted to Pulmonary RevatioÂ® Restricted dysfunction‐>Phosphodiesterase type‐5 inhibitors‐>SILDENAFIL Hypertension only 8.2 Drugs affecting the immune response‐>8.2.4 Other immunomodulating drugs‐>Lenalidomide, pomalidomide, and RevlimidÂ® Restricted thalidomide‐>LENALIDOMIDE Prior funding approval required Virology/Microbiology/ID approval RIBAVIRIN Restricted 5.3 Antiviral drugs‐>5.3.5 Respiratory syncytial virus only. RIFABUTIN Restricted 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs ID/Microbiology approval only.

Restricted to Shunt meningitis; TB; Meningococcal eradication therapy. Microbiology/ID approval required RifadinÂ® Restricted 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs‐>RIFAMPICIN for all other indications.

Restricted to Shunt meningitis; TB; Meningococcal eradication therapy. Microbiology/ID approval required RIFAMPICIN Restricted 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs for all other indications.

Restricted to Shunt meningitis; TB; Meningococcal eradication therapy. Microbiology/ID approval required Rifampicin Restricted 5.1 Antibacterial drugs‐>5.1.9 Antituberculosis drugs‐>RIFAMPICIN for all other indications.

4.9 Drugs used in parkinsonism and related disorders‐>4.9.3 Drugs Restriced to neurology only. used in essential tremor, chorea, tics, and related disorders‐ Agreement must be in place that the RilutekÂ® Restricted >RILUZOLE patients GP will continue treatment.

Restriced to neurology only. 4.9 Drugs used in parkinsonism and related disorders‐>4.9.3 Drugs Agreement must be in place that the RILUZOLE Restricted used in essential tremor, chorea, tics, and related disorders patients GP will continue treatment. 4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison Risperdal ConstaÂ® Restricted Antipsychotic depot injections‐>RISPERIDONE psychiatry team.

4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison RISPERIDONE Restricted Antipsychotic drugs‐>Second‐generation antipsychotic drugs psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison RISPERIDONE Restricted Antipsychotic depot injections psychiatry team.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Restricted to the Child & 4.4 CNS stimulants and drugs used for attention deficit hyperactivity Adolescent Mental Health Service RitalinÂ® Restricted disorder‐>METHYLPHENIDATE HYDROCHLORIDE only.

Prior funding approval required for rheumatology only. Restricted to 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that haematology, nephrology and RITUXIMAB Restricted suppress the rheumatic disease process‐>Cytokine modulators rheumatology. NICE guidance Under haemophilia approval for Rivaroxaban Restricted 2.8 Anticoagulants and protamine‐>2.8.2 Oral anticoagulants treatment of DVT only 2.8 Anticoagulants and protamine‐>2.8.2 Oral anticoagulants‐ Under haemophilia approval for RIVAROXABAN Restricted >Rivaroxaban treatment of DVT only

Approved as 6th line for refractory 9.1 Anaemias and some other blood disorders‐>9.1.4 Drugs used in ITP, treatment algorithm available. ROMIPLOSTIM Restricted platelet disorders‐>Idiopathic thrombocytopenic purpura Funding approval required. ROSUVASTATIN Restricted 2.12 Lipid‐regulating drugs‐>Statins Restricted to the lipid clinic. 4.9 Drugs used in parkinsonism and related disorders‐>4.9.1 Dopaminergic drugs used in Parkinson's disease‐>Dopamine‐receptor Restricted to peri‐operative ROTIGOTINE Restricted agonists Parkinson's patients only. 13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial preparations‐>13.10.1.2 Antibacterial preparations also used The gel is restricted for the treatment RozexÂ® Restricted systemically‐>METRONIDAZOLE of rosacea only. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase RUXOLITINIB Restricted inhibitors 6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.2 Posterior pituitary hormones and antagonists‐>Tolvaptan‐ SamscaÂ® Restricted >TOLVAPTAN Restricted to endocrinology only.

8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.3 Somatostatin analogues‐ Prior funding approval required. First Sandostatin LarÂ® Restricted >OCTREOTIDE‐>Depot preparation dose free of charge

2.6 Nitrates, calcium‐channel blockers, and other antianginal drugs‐ SecuronÂ® Restricted >2.6.2 Calcium‐channel blockers‐>VERAPAMIL HYDROCHLORIDE Restricted to cardiology use only. 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.5 Mecillinams‐ SelexidÂ® Restricted >PIVMECILLINAM HYDROCHLORIDE Microbiology approval required. Restricted to treatment and prevention of PCP infection; Chemotherapy protocols. 5.1 Antibacterial drugs‐>5.1.8 Sulfonamides and trimethoprim‐>CO‐ Microbiology approval required for all SeptrinÂ® Restricted TRIMOXAZOLE other indications. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>First‐generation antipsychotic drugs‐ Initiate after discussion with liaison SerenaceÂ® Restricted >HALOPERIDOL psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>Second‐generation antipsychotic drugs‐ Initiate after discussion with liaison SeroquelÂ® Restricted >QUETIAPINE psychiatry team.

SEVELAMER HYDROCHLORIDE Restricted 9.5 Minerals‐>9.5.2 Phosphorus‐>9.5.2.2 Phosphate‐binding agents Restricted to renal patients only. 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator See individual brands for restictions SILDENAFIL Restricted antihypertensive drugs on prescribing.

Restricted to Urology, Endocrinology, 7.4 Drugs for genito‐urinary disorders‐>7.4.5 Drugs for erectile Pulmonary Hypertension, and SILDENAFIL Restricted dysfunction‐>Phosphodiesterase type‐5 inhibitors Rheumatology only 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that suppress the rheumatic disease process‐>Cytokine modulators‐ SimponiÂ® Restricted >GOLIMUMAB

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Prior funding required for treatment of lymphoma with radiolabelled 8.2 Drugs affecting the immune response‐>8.2.2 Corticosteroids and basiliximabApproved for Renal SimulectÂ® Restricted other immunosuppressants‐>BASILIXIMAB transplant patients.

11.8 Miscellaneous ophthalmic preparations‐>11.8.2 Ocular diagnostic and peri‐operative preparations and photodynamic Single use Restricted treatment‐>Ocular peri‐operative drugs‐>DICLOFENAC SODIUM Restricted to Opthalmology.

3.3 Cromoglicate and related therapy, leukotriene receptor antagonists, and phosphodiesterase type‐4 inhibitors‐>3.3.2 Restricted to Thoracic Medicine and SingulairÂ® Restricted Leukotriene receptor antagonists‐>MONTELUKAST Paediatrics only. 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other Restricted to initiation by SITAGLIPTIN Restricted antidiabetic drugs endocrinology only SODIUM CROMOGLICATE Restricted 1.5 Chronic bowel disorders‐>1.5.4 Food allergy Restricted to the allergy clinic SODIUM STIBOGLUCONATE Restricted 5.4 Antiprotozoal drugs‐>5.4.5 Leishmaniacides Restricted to ID/Microbiology. 13.8 Sunscreens and camouflagers‐>13.8.1 Sunscreen preparations‐ SolarazeÂ® Restricted >Photodamage‐>DICLOFENAC SODIUM Restricted to Dermatologists. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>Second‐generation antipsychotic drugs‐ Initiate after discussion with liaison SolianÂ® Restricted >AMISULPRIDE psychiatry team.

7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary Restricted to 2nd line therapy in SOLIFENACIN SUCCINATE Restricted frequency, enuresis, and incontinence‐>Urinary incontinence overactive bladder. 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.3 Somatostatin analogues‐ Prior funding approval required. First Somatuline AutogelÂ® Restricted >LANREOTIDE dose free of charge 8.3 Sex hormones and hormone antagonists in malignant disease‐ >8.3.4 Hormone antagonists‐>8.3.4.3 Somatostatin analogues‐ RESTRICTED TO ENDOCRINE AND SomatulineÂ® LA Restricted >LANREOTIDE LIVER UNITS

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.1 Hypothalamic and anterior pituitary hormones and anti‐oestrogens‐ >Anterior pituitary hormones‐>Growth hormone receptor antagonists Requires funding approval prior to SomavertÂ® Restricted >PEGVISOMANT prescribing. Prior funding approval required via 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase CDF for HCC and Follicular Thyroid SORAFENIB Restricted inhibitors cancer

ORAL preparations restricted to Dermatology; HIV; Haematology; Marlborough OPD.INTRAVENOUS preparations restricted to Haematology. Microbiology approval SporanoxÂ® Restricted 5.2 Antifungal drugs‐>5.2.1 Triazole antifungals‐>ITRACONAZOLE required for all other indications. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase SprycelÂ® Restricted inhibitors‐>DASATINIB Prior funding approval required

4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison Antipsychotic drugs‐>First‐generation antipsychotic drugs‐ psychiatry team.Stelazine Syrup StelazineÂ® Restricted >TRIFLUOPERAZINE (1mg/5ml) is not kept at The RFH. Restricted to the Child & 4.4 CNS stimulants and drugs used for attention deficit hyperactivity Adolescent Mental Health Service StratteraÂ® Restricted disorder‐>ATOMOXETINE only.

6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and Restricted to 2nd line use as per NICE Strontium ranelate Restricted other drugs affecting bone metabolism guidance

6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and Restricted to 2nd line use as per NICE STRONTIUM RANELATE Restricted other drugs affecting bone metabolism‐>Strontium ranelate guidance 14.5 Immunoglobulins‐>14.5.1 Normal immunoglobulin‐>NORMAL SubcuviaÂ® Restricted IMMUNOGLOBULIN‐>For subcutaneous use Restricted to immunology use only 14.5 Immunoglobulins‐>14.5.1 Normal immunoglobulin‐>NORMAL SubgamÂ® Restricted IMMUNOGLOBULIN‐>For subcutaneous use Restricted to immunology use only

15.1 General anaesthesia‐>15.1.6 Drugs for reversal of neuromuscular SUGAMMADEX Restricted blockade‐>Other drugs for reversal of neuromuscular blockade Restricted to Theatres

SULFADIAZINE Restricted 5.1 Antibacterial drugs‐>5.1.8 Sulfonamides and trimethoprim Microbiology/ID approval only. 5.1 Antibacterial drugs‐>5.1.8 Sulfonamides and trimethoprim‐ Sulfadiazine Restricted >SULFADIAZINE Microbiology/ID approval only 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison SULPIRIDE Restricted Antipsychotic drugs‐>First‐generation antipsychotic drugs psychiatry team.

4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison Sulpiride Restricted Antipsychotic drugs‐>First‐generation antipsychotic drugs‐>SULPIRIDE psychiatry team.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison SulporÂ® Restricted Antipsychotic drugs‐>First‐generation antipsychotic drugs‐>SULPIRIDE psychiatry team. Sumatriptan is restricted to neurologists and is for in‐patient 4.7 Analgesics‐>4.7.4 Antimigraine drugs‐>4.7.4.1 Treatment of acute prescribing only.The nasal spray is SUMATRIPTAN Restricted migraine‐>5HT1‐receptor agonists NOT formulary. Sumatriptan is restricted to neurologists and is for in‐patient 4.7 Analgesics‐>4.7.4 Antimigraine drugs‐>4.7.4.1 Treatment of acute prescribing only.The nasal spray is Sumatriptan Restricted migraine‐>5HT1‐receptor agonists‐>SUMATRIPTAN NOT formulary.

Prior funding approval requiredvia CDF for the treatment of 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase pancreatic neuroendocrine tumours. SUNITINIB Restricted inhibitors Notification only for RCC Restricted to Marlborough OPD and 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and used for IV/PO switch with SupraxÂ® Restricted other beta‐lactams‐>5.1.2.1 Cephalosporins‐>CEFIXIME Microbiology approval only. 6.7 Other endocrine drugs‐>6.7.2 Drugs affecting gonadotrophins‐ Restricted to consultant SuprecurÂ® Restricted >Gonadorelin analogues‐>BUSERELIN gynaecologists only.

Prior funding approval required. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase Approved for the treatment of SutentÂ® Restricted inhibitors‐>SUNITINIB pancreatic neuroendocrine tumours.

SynagisÂ® Restricted 5.3 Antiviral drugs‐>5.3.5 Respiratory syncytial virus‐>PALIVIZUMAB Restricted to Neonatology. 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Vitamin D and Restricted to Dermatology and TACALCITOL Restricted analogues Rheumatology only. 13.5 Preparations for eczema and psoriasis‐>13.5.3 Drugs affecting TACROLIMUS Restricted the immune response Restricted to Dermatology only. 7.4 Drugs for genito‐urinary disorders‐>7.4.5 Drugs for erectile For Urology and Endocrinology use TADALAFIL Restricted dysfunction‐>Phosphodiesterase type‐5 inhibitors only Talimogene laherparepvec Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs Virology/Microbiology/ID approval TamifluÂ® Restricted 5.3 Antiviral drugs‐>5.3.4 Influenza‐>OSELTAMIVIR only.

Prior funding approval required. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase Restricted for treatment of non‐small TarcevaÂ® Restricted inhibitors‐>ERLOTINIB cell lung cancer only

Restricted to Haematology; Oncology; Renal Dialysis; NICU; Surgical prophylaxis in MRSA‐positive or Beta‐ lactam allergic patients; Treatment of MRSA infection (NOT colonisation or bacteraemia); Treatment of central venous catheter related infections. 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐ Microbiology approval required for all TargocidÂ® Restricted >Glycopeptides‐>TEICOPLANIN other indications. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Bexarotene‐ TargretinÂ® Restricted >BEXAROTENE Prior funding approval required TarividÂ® Restricted 5.1 Antibacterial drugs‐>5.1.12 Quinolones‐>OFLOXACIN ID/Microbiology approval only. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase TasignaÂ® Restricted inhibitors‐>NILOTINIB Prior funding approval required

Restricted to community acquired pneumonia patients with beta‐lactam allergy. Microbiology approval TavanicÂ® Restricted 5.1 Antibacterial drugs‐>5.1.12 Quinolones‐>LEVOFLOXACIN required for all other indications. Prior funding approval required for treatment of prostate cancer and adjuvant treatment of breast cancer. Restricted for treatment of breast, 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Taxanes‐ prostate and non‐small cell lung TaxotereÂ® Restricted >DOCETAXEL cancers

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ >3.4.1 Antihistamines‐>Non‐sedating antihistamines‐>FEXOFENADINE TelfastÂ® Restricted HYDROCHLORIDE Restricted to dermatology only. 5.1 Antibacterial drugs‐>5.1.1 Penicillins‐>5.1.1.2 Penicillinase‐ TEMOCILLIN Restricted resistant penicillins Microbiology approval required.

Prior funding approval required for treatment of newly diagnosed glioblastoma multiforme.Also 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Dacarbazine approved as part of chemotherapy TemodalÂ® Restricted and temozolomide‐>TEMOZOLOMIDE regime (with capecitabine) for NET 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Dacarbazine TEMOZOLOMIDE Restricted and temozolomide Restricted to NET patients Approved as part of regime (with 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Dacarbazine capecitabine) for neuroendocrine Temozolomide Restricted and temozolomide‐>TEMOZOLOMIDE tumours. 2.10 Stable angina, acute coronary syndromes, and fibrinolysis‐ TENECTEPLASE Restricted >2.10.2 Fibrinolytic drugs Restricted to cardiology only. 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal Approved only for dermatology TERBINAFINE Restricted preparations patients. 13.10 Anti‐infective skin preparations‐>13.10.2 Antifungal Approved only for dermatology Terbinafine Restricted preparations‐>TERBINAFINE patients. 6.6 Drugs affecting bone metabolism‐>6.6.1 Calcitonin and Restricted to Endocrinology and TERIPARATIDE Restricted parathyroid hormone Rheumatology use only

6.4 Sex hormones‐>6.4.2 Male sex hormones and antagonists‐ TestogelÂ® Restricted >TESTOSTERONE AND ESTERS‐>Transdermal preparations Approved for endocrinology use only. 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ Restricted to gynaecology and the TIBOLONE Restricted >6.4.1.1 Oestrogens and HRT menopause clinic only. TICAGRELOR Restricted 2.9 Antiplatelet drugs restricted to Cardiology Tigecycline Restricted 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines Microbiology approval only. TIGECYCLINE Restricted 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines‐>Tigecycline Microbiology approval only.

3.3 Cromoglicate and related therapy, leukotriene receptor antagonists, and phosphodiesterase type‐4 inhibitors‐>3.3.1 TiladeÂ® CFC‐free Inhaler Restricted Cromoglicate and related therapy‐>NEDOCROMIL SODIUM Restricted to Paediatrics only. 11.6 Treatment of glaucoma‐>Beta‐blockers‐>TIMOLOL‐>Once‐daily TimoptolÂ®‐LA Restricted preparations Restricted to Opthalmologists only.

TINIDAZOLE Restricted 5.1 Antibacterial drugs‐>5.1.11 Metronidazole and tinidazole Microbiology/ID approval only. TINIDAZOLE Restricted 5.4 Antiprotozoal drugs‐>5.4.2 Amoebicides Microbiology/ID approval only. Restricted to use as per London HIV TIPRANAVIR Restricted 5.3 Antiviral drugs‐>5.3.1 HIV infection‐>Protease inhibitors consortium guidelines. TIROFIBAN Restricted 2.9 Antiplatelet drugs Restricted to cardiology only. 10.2 Drugs used in neuromuscular disorders‐>10.2.2 Skeletal muscle Approved for use by neurologists TIZANIDINE Restricted relaxants only. 10.2 Drugs used in neuromuscular disorders‐>10.2.2 Skeletal muscle Approved for use by neurologists Tizanidine Restricted relaxants‐>TIZANIDINE only.

Approved for Castleman's disease 10.1 Drugs used in rheumatic diseases and gout‐>10.1.3 Drugs that (National Amyloidosis Centre) and TOCILIZUMAB Restricted suppress the rheumatic disease process‐>Cytokine modulators also for Rheumatoid arthritis.

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.2 Tolvaptan Restricted Posterior pituitary hormones and antagonists Restricted to endocrinology only.

6.5 Hypothalamic and pituitary hormones and anti‐oestrogens‐>6.5.2 TOLVAPTAN Restricted Posterior pituitary hormones and antagonists‐>Tolvaptan Restricted to endocrinology only. Approved for the treatment of relapsed small‐call lung cancer as per NICE guidance. Prior funding approval required. NICE guidance for the 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐ treatment of replased small‐cell lung TOPOTECAN Restricted >Topoisomerase I inhibitors cancer 15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ operative drugs‐>15.1.4.2 Non‐opioid analgesics‐>KETOROLAC ToradolÂ® Restricted TROMETAMOL Restricted to anaesthetists.

Prior funding approval required. 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator Restricted to the treatment of TracleerÂ® Restricted antihypertensive drugs‐>BOSENTAN pulmonary hypertension. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase TRAMETINIB Restricted inhibitors

TranstecÂ® Restricted 4.7 Analgesics‐>4.7.2 Opioid analgesics‐>BUPRENORPHINE‐>Patches Restricted to the pain team. Trastuzumab Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Notification only. Approved for breast cancer and adenocarcinoma of the stomach in TRASTUZUMAB Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Trastuzumab line with NICE guidance. Trastuzumab emtansine Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Trastuzumab Prior funding approval required via TRASTUZUMAB EMTANSINE Restricted emtansine CDF 11.6 Treatment of glaucoma‐>Prostaglandin analogues and TravatanÂ® Restricted prostamides‐>TRAVOPROST Restricted to Opthalmologists only. 6.4 Sex hormones‐>6.4.1 Female sex hormones and their modulators‐ >6.4.1.1 Oestrogens and HRT‐>OESTROGENS FOR HRT‐>Estradiol with TridestraÂ® Restricted progestogen Restricted to gynaecology 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison TRIFLUOPERAZINE Restricted Antipsychotic drugs‐>First‐generation antipsychotic drugs psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Antipsychotic drugs‐>First‐generation antipsychotic drugs‐ Initiate after discussion with liaison Trifluoperazine Restricted >TRIFLUOPERAZINE psychiatry team. Restricted to neurology only.Only the 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐ 150mg and 300mg tablets kept at the TrileptalÂ® Restricted >Carbamazepine and related antiepileptics‐>OXCARBAZEPINE RFH.

6.7 Other endocrine drugs‐>6.7.2 Drugs affecting gonadotrophins‐ Restricted to Paediatrics for central TRIPTORELIN Restricted >Gonadorelin analogues precociuos puberty only. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Arsenic TrisenoxÂ® Restricted trioxide‐>ARSENIC TRIOXIDE Prior funding approval required 5.1 Antibacterial drugs‐>5.1.3 Tetracyclines‐>Tigecycline‐ TygacilÂ® Restricted >TIGECYCLINE Microbiology approval only.

8.2 Drugs affecting the immune response‐>8.2.4 Other Prior funding approval required. TysabriÂ® Restricted immunomodulating drugs‐>Natalizumab‐>NATALIZUMAB Restricted to Neurology patients.

8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase Approved for breast cancer. Prior TyverbÂ® Restricted inhibitors‐>LAPATINIB funding approval required. 7.3 Contraceptives‐>7.3.5 Emergency contraception‐>Hormonal Restricted for Marlborough Clinic use ULIPRISTAL ACETATE Restricted methods only.

15.1 General anaesthesia‐>15.1.4 Sedative and analgesic peri‐ Restricted to theatres ‐ neurosurgery UltivaÂ® Restricted operative drugs‐>15.1.4.3 Opioid analgesics‐>REMIFENTANIL use only

Restricted to Haematology; Oncology; Immunosuppressed Transplant patients; HIV; Suspected viral meningitis/encephalitis; Dermatology (eczema herpeticum); Virology 5.3 Antiviral drugs‐>5.3.2 Herpesvirus infections‐>5.3.2.1 Herpes approval required for all other VALACICLOVIR Restricted simplex and varicellaâ€“zoster infection indications. Restricted to HIV; Haematology; Oncology; Liver and Renal Transplants; Other immunosuppressed patients. Virology 5.3 Antiviral drugs‐>5.3.2 Herpesvirus infections‐>5.3.2.2 approval required for all other ValcyteÂ® Restricted Cytomegalovirus infection‐>VALGANCICLOVIR indications. Restricted to HIV; Haematology; Oncology; Liver and Renal Transplants; Other immunosuppressed patients. Virology 5.3 Antiviral drugs‐>5.3.2 Herpesvirus infections‐>5.3.2.2 approval required for all other VALGANCICLOVIR Restricted Cytomegalovirus infection indications. 4.2 Drugs used in psychoses and related disorders‐>4.2.3 Drugs used Initiate after discussion with liaison Valproate Restricted for mania and hypomania psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.3 Drugs used Initiate after discussion with liaison VALPROIC ACID Restricted for mania and hypomania‐>Valproate psychiatry team.

Restricted to Haematology; Oncology; Immunosuppressed Transplant patients; HIV; Suspected viral meningitis/encephalitis; Dermatology (eczema herpeticum); Neonatology 5.3 Antiviral drugs‐>5.3.2 Herpesvirus infections‐>5.3.2.1 Herpes (chicken pox). Virology approval ValtrexÂ® Restricted simplex and varicellaâ€“zoster infection‐>VALACICLOVIR required for all other indications. 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐ VANCOMYCIN Restricted >Glycopeptides

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

Restricted to Endocarditis; Renal Dialysis; Opthalmology (intracameral); Neurosurgery (intrathecal); MSSA bacteraemia in penicillin allergy and MRSA bacteraemia. Oral vancomycin for Severe or relapsed C. difficile infection. Microbiology approval required for all other indications. http://freenet/guidelines/1275_ADUL 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐ T_VANCOMYCIN_DOSING_GUIDELINE Vancomycin Restricted >Glycopeptides‐>VANCOMYCIN S_November_2011_Final_(2).pdf 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase VANDETANIB Restricted inhibitors 13.9 Shampoos and other preparations for scalp and hair conditions‐ Restricted to dermatology and VaniqaÂ® Restricted >Hirsutism‐>EFLORNITHINE endocrinology only. 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Bortezomib‐ VelcadeÂ® Restricted >BORTEZOMIB Prior funding approval required 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator VentavisÂ® Restricted antihypertensive drugs‐>ILOPROST For ITU use only. 7.4 Drugs for genito‐urinary disorders‐>7.4.2 Drugs for urinary frequency, enuresis, and incontinence‐>Urinary incontinence‐ Restricted to 2nd line therapy in VesicareÂ® Restricted >SOLIFENACIN SUCCINATE overactive bladder.

Restricted to Haematology (in discussion with Microbiology as per protocol). Microbiology approval VfendÂ® Restricted 5.2 Antifungal drugs‐>5.2.1 Triazole antifungals‐>VORICONAZOLE required for all other indications.

Restricted to Urology, Endocrinology, 7.4 Drugs for genito‐urinary disorders‐>7.4.5 Drugs for erectile Pulmonary Hypertension, and ViagraÂ® Restricted dysfunction‐>Phosphodiesterase type‐5 inhibitors‐>SILDENAFIL Rheumatology only 6.1 Drugs used in diabetes‐>6.1.2 Antidiabetic drugs‐>6.1.2.3 Other VictozaÂ® Restricted antidiabetic drugs‐>LIRAGLUTIDE Restricted to endocrinology. Approved by Haematology for MDS, VidazaÂ® Restricted 8.1 Cytotoxic drugs‐>8.1.3 Antimetabolites‐>AZACITIDINE CMML, AML only. 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Lacosamide‐ Restricted to neurology as second VimpatÂ® Restricted >LACOSAMIDE line therapy.

8.2 Drugs affecting the immune response‐>8.2.4 Other Prior funding approval required. ViraferonPegÂ® Restricted immunomodulating drugs‐>Interferon alfa‐>PEGINTERFERON ALFA Restricted to hepatology only.

7.4 Drugs for genito‐urinary disorders‐>7.4.5 Drugs for erectile Restricted to Urology and ViridalÂ® Duo Restricted dysfunction‐>Alprostadil‐>ALPROSTADIL‐>Intracavernosal injection Endocrinology consultants Vismodegib Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs Prior funding required via CDF

VISMODEGIB Restricted 8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Vismodegib Prior funding required via CDF

Prior funding approval required. 2.5 Hypertension and heart failure‐>2.5.1 Vasodilator Restricted to the treatment of VolibrisÂ® Restricted antihypertensive drugs‐>AMBRISENTAN pulmonary hypertension. 11.8 Miscellaneous ophthalmic preparations‐>11.8.2 Ocular diagnostic and peri‐operative preparations and photodynamic treatment‐>Ocular peri‐operative drugs‐>DICLOFENAC SODIUM‐ VoltarolÂ® Ophtha Restricted >Single use Restricted to Opthalmology.

Restricted to Haematology (in discussion with Microbiology as per protocol). Microbiology approval VORICONAZOLE Restricted 5.2 Antifungal drugs‐>5.2.1 Triazole antifungals required for all other indications.

8.1 Cytotoxic drugs‐>8.1.5 Other antineoplastic drugs‐>Protein kinase Approved for metastatic renal cell VotrientÂ® Restricted inhibitors‐>PAZOPANIB carcinoma, in line with NICE guidance 13.7 Preparations for warts and calluses‐>Anogenital warts‐ WarticonÂ® Restricted >PODOPHYLLOTOXIN Restricted to Dermatology only. 5.4 Antiprotozoal drugs‐>5.4.8 Drugs for pneumocystis pneumonia‐ WellvoneÂ® Restricted >ATOVAQUONE ID/Microbiology approval only. 13.5 Preparations for eczema and psoriasis‐>13.5.2 Preparations for psoriasis‐>Topical preparations for psoriasis‐>Vitamin D and Restricted to Dermatology patients With betamethasone Restricted analogues‐>CALCIPOTRIOL only. With poloxamer â€˜188â€™ (as co‐ Restricted to oncologist and danthramer) Restricted 1.6 Laxatives‐>1.6.2 Stimulant laxatives‐>DANTRON geriatricians 11.6 Treatment of glaucoma‐>Prostaglandin analogues and XalatanÂ® Restricted prostamides‐>LATANOPROST FOR OPTHALMOLOGISTS ONLY. 2.8 Anticoagulants and protamine‐>2.8.2 Oral anticoagulants‐ Under haemophilia approval for XareltoÂ® Restricted >Rivaroxaban‐>RIVAROXABAN treatment of DVT only 4.5 Obesity‐>4.5.1 Anti‐obesity drugs acting on the gastro‐intestinal XenicalÂ® Restricted tract‐>ORLISTAT Restricted to the Lipid Clinic Only.

Pharmacy Department October 2017 Royal Free Hospital Drug Formulary

3.4 Antihistamines, hyposensitisation, and allergic emergencies‐ Restricted to respiratory consultant XolairÂ® Restricted >3.4.2 Allergen immunotherapy‐>Omalizumab‐>OMALIZUMAB prescribing only 10.2 Drugs used in neuromuscular disorders‐>10.2.2 Skeletal muscle Approved for use by neurologists ZanaflexÂ® Restricted relaxants‐>TIZANIDINE only. Virology/Microbiology/ID approval ZANAMIVIR Restricted 5.3 Antiviral drugs‐>5.3.4 Influenza only. ZedbacÂ® Restricted 5.1 Antibacterial drugs‐>5.1.5 Macrolides‐>AZITHROMYCIN

Restricted to opthalmology and for 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and patients with beta lactam allergy as ZinacefÂ® Restricted other beta‐lactams‐>5.1.2.1 Cephalosporins‐>CEFUROXIME per Trust antibiotic guidelines.

Restricted to opthalmology and for 5.1 Antibacterial drugs‐>5.1.2 Cephalosporins, carbapenems, and patients with beta lactam allergy as ZinnatÂ® Restricted other beta‐lactams‐>5.1.2.1 Cephalosporins‐>CEFUROXIME per Trust antibiotic guidelines.

Restricted to Marlborough OPD; Obs & Gynae (TOP); Renal transplant. Microbiology approval ZithromaxÂ® Restricted 5.1 Antibacterial drugs‐>5.1.5 Macrolides‐>AZITHROMYCIN required for all other indications.

Restricted to Oncologists, Haematologists, HIV and Paediatricians.Used 2nd line for post‐ operative nausea and vomiting.The 4.6 Drugs used in nausea and vertigo‐>5HT3‐receptor antagonists‐ Oral Lyophilisates are not kept at The ZofranÂ® Restricted >ONDANSETRON Royal Free Hospital.

6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and ZOLEDRONIC ACID Restricted other drugs affecting bone metabolism‐>Bisphosphonates 4.7 Analgesics‐>4.7.4 Antimigraine drugs‐>4.7.4.1 Treatment of acute ZOLMITRIPTAN Restricted migraine‐>5HT1‐receptor agonists Restricted to Neurologists. 6.6 Drugs affecting bone metabolism‐>6.6.2 Bisphosphonates and other drugs affecting bone metabolism‐>Bisphosphonates‐ ZometaÂ® Restricted >ZOLEDRONIC ACID Restricted to Myeloma patients only

Restricted to Neurologists.The 4.7 Analgesics‐>4.7.4 Antimigraine drugs‐>4.7.4.1 Treatment of acute orodispersible tablets are not ZomigÂ® Restricted migraine‐>5HT1‐receptor agonists‐>ZOLMITRIPTAN available at The Royal Free Hospital. 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Zonisamide‐ ZonegranÂ® Restricted >ZONISAMIDE Restricted to neurology only. Zonisamide Restricted 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies Restricted to neurology only.

ZONISAMIDE Restricted 4.8 Antiepileptic drugs‐>4.8.1 Control of the epilepsies‐>Zonisamide Restricted to neurology only.

Aciclovir INJECTION restricted to:Haematology; Oncology; Immunosuppressed transplant patients; HIV; Suspected viral meningitis/encephalitis; Dermatology (eczema herpeticum); Neonatology (chickenpox).In all other indications 5.3 Antiviral drugs‐>5.3.2 Herpesvirus infections‐>5.3.2.1 Herpes seek virology approval before ZoviraxÂ® Restricted simplex and varicellaâ€“zoster infection‐>ACICLOVIR prescribing intravenous aciclovir. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison ZUCLOPENTHIXOL Restricted Antipsychotic drugs‐>First‐generation antipsychotic drugs psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.1 Initiate after discussion with liaison ZUCLOPENTHIXOL ACETATE Restricted Antipsychotic drugs‐>First‐generation antipsychotic drugs psychiatry team. 4.2 Drugs used in psychoses and related disorders‐>4.2.2 Initiate after discussion with liaison ZUCLOPENTHIXOL DECANOATE Restricted Antipsychotic depot injections psychiatry team. 13.10 Anti‐infective skin preparations‐>13.10.1 Antibacterial preparations‐>13.10.1.2 Antibacterial preparations also used Restricted for the treatment of ZyometÂ® Restricted systemically‐>METRONIDAZOLE rosacea only.

Initiate after discussion with liaison 4.2 Drugs used in psychoses and related disorders‐>4.2.1 psychiatry team. The orodispersible Antipsychotic drugs‐>Second‐generation antipsychotic drugs‐ tablets are restricted to in‐patient use ZyprexaÂ® Restricted >OLANZAPINE only. 5.1 Antibacterial drugs‐>5.1.7 Some other antibacterials‐>Linezolid‐ ZyvoxÂ® Restricted >LINEZOLID Microbiology approval only.

Pharmacy Department October 2017