At a glance Br J Ophthalmol: first published as 10.1136/bjophthalmol-2019-314158 on 22 March 2019. Downloaded from Highlights from this issue

‍ ‍ ‍ ‍ doi:10.1136/bjophthalmol-2019-314158 Keith Barton, James Chodosh, Jost B Jonas , Editors in chief

Choriocapillaris and retinal vascular Premacular membrane formation Compared performance of spot and plexus density of diabetic eyes using after scleral buckling for primary SW800 photoscreeners on Chinese Split-spectrum Amplitude-Decorrelation rhegmatogenous retinal detachment: a children (see page 517) spectral domain optical coherence prospective study and pathophysiological Compared with standardised ophthalmic tomography angiography (see page 452) insights (see page 481) exams with ROC, both Spot and SW800 Capillary perfusion density in Choriocapil- This study reports a high frequency of photoscreener provide accurate measure- laris and retinal vascular plexuses in diabetic postoperative premacular membrane ments of refractive error and strabismus, patients were observed in association with formation after rhegmatogenous retinal and satisfactory performance in detecting worsening retinopathy in comparison with detachment repair with scleral buck- amblyopia risk factors in Chinese children healthy eyes using split-spectrum ampli- ling alone. In detachments involving the between 4–6 years of age. tude decorrelation spectral domain optical macular region, postoperative premac- Delayed surgical treatment of orbital coherence tomography angiography. ular membranes were severe, tending to trapdoor fracture in the pediatric patients anatomical progression and functional (see page 523) Possible connection of short deterioration. posterior ciliary arteries to choroidal Prompt surgical intervention right after Neovascularization in eyes with Intravitreal chemotherapy in diagnosis is preferable in paediatric patients pathologic myopia (see page 457) retinoblastoma: expanded use beyond with trapdoor fracture regardless of the Residual blood flow was detected in eyes intravitreal seeds (see page 488) entrapped contents, even though some with Myopic choroidal neovasculariza- This retrospective review highlights the recovery might be possible in the long term. tion (mCNV) retained detectable blood successful use of intravitreal chemotherapy to treat subretinal seeds and retinal tumours. Incidence and clinical characteristics of flow even in the atrophic phase on Optical congenital nasolacrimal duct obstruction Coherence Tomography (OCT) angiog- The efficacy of intravitreal conbercept (see page 527) raphy. OCT B scans and Indocyanine Green injection in the treatment of retinopathy In this population-based cohort of 17 713 of Prematurity (see page 494) Angiography revealed that the mCNVs newborns, 1 in nine infants developed Forty-eight eyes of 24 infants with ROP were continuous with scleral branches of congenital nasolacrimal duct obstruction, were analysed after intravitreal conbercept the short posterior ciliary arteries. accompanied primarily by mucopurulent injection treatment. A total of 83.3% of the discharge, without gender predilection, and Long-term visual outcome and its infants obtained regression of retinopathy associated with premature birth and Cauca- predictors in macular oedema secondary of prematurity after only one injection. to retinal vein occlusion treated with sian race. Iris anomalies and the incidence of dexamethasone implant (see page 463) Clinical presentation and management of In a 24 month study, baseline visual acuity, ACTA2 mutation (see page 499) http://bjo.bmj.com/ Iris flocculi have been linked to thoracic corneal fistula (see page 530) early treatment response and the require- Corneal fistula is often underdiagnosed and ment for additional therapy, were predictive aortic aneurysm and dissection due to ACTA2 mutations. In this series, no chil- can cause complications like phthisis bulbi, of the long-term outcome in patients with endophthalmitis and panophthalmitis. This macular oedema secondary to retinal vein dren with iris flocculi had ACTA2 mutation while 2 of 3 children with congenital mydri- case series highlights the importance of occlusion treated with a dexamethasone careful clinical examination in patients of implant. asis did.

healed keratitis that may harbour a fistula on September 30, 2021 by guest. Protected copyright. Variability in the ocular phenotype in Microvascular abnormalities secondary mucopolysaccharidosis (see page 504) Is combined cataract surgery to radiation therapy in neovascular age- Prospective observational study, using associated with acute post-operative related macular degeneration: findings objective measures of ocular phenotype endophthalmitis? A nationwide study from the INTREPID clinical trial (see in Mucopolysaccharidosis and correlating from 2005 to 2014. (see page 534) page 469) findings with disease type, genotype and According to the analysis of the French Stereotactic Radiotherapy led to Microvas- treatment efficacy. Ocular phenotype was nationwide medical-administrative data- cular Abnormalities (MVAs) that are distin- found to be variable, and ocular imaging base, the incidence of acute post-operative guishable from nonspecific retinal vessel useful, in detecting complications. endophthalmitis was higher after combined abnormalities. Most MVAs did not result cataract surgery than after cataract surgery in visual loss. This study might help in the White matter microstructural alterations as a standalone procedure. differentiation from SRT induced MVAs in amblyopic adults revealed by diffusion spectrum imaging with systematic Cataract surgery refractive outcomes - from other entities. tractography-based automatic analysis representative standards in a National Correlation between aqueous flare and (see page 511) Health Service setting. (see page 539) residual visual field area in retinitis Diffusion spectrum imaging in ambly- We present refractive outcomes from pigmentosa (see page 475) opia adults suggests a possible association routine NHS cataract surgery. Benchmark Aqueous flare, as measured with a laser flare between abnormal early visual processing standards set by the Royal College of cell metre, was negatively correlated with and alterations of white matter architecture, Ophthalmologists are achievable, however, the residual visual field area in patients with which may be related to some of amblyo- expecting all NHS units to meet higher retinitis pigmentosa. pia-related deficits. benchmark standards is not yet feasible.

Br J Ophthalmol April 2019 Vol 103 No 4 i At a glance Br J Ophthalmol: first published as 10.1136/bjophthalmol-2019-314158 on 22 March 2019. Downloaded from

Femtosecond laser-assisted cataract Biomechanical Assessment of Healthy Dual-target, real-time PCR for the surgery for the white cataract (see page and Keratoconic Corneas (with/without diagnosis of intraocular Toxoplasma 544) Crosslinking) using dynamic ultra-high- gondii infections (see page 569) In this case series of 58 white cataracts, speed Scheimpflug Technology and the We present a single-reaction, internally-con- the main complication of femtosecond relevance of the parameter (A1L-A2L) trolled, dual-target (B1-Rep529) real-time (see page 558) laser-assisted cataract surgery was incom- PCR for intraocular T. gondii. This dual- This study identifies corneal biomechan- plete capsulotomy (17.2%). Risk factors for target design maximises inclusivity and ical parameters in order to characterise sensitivity, without loss of specificity. incomplete capsulotomy were Morgagnian and discriminate noncrosslinked and cross- Association of human antigen class cataract and increased lens thickness. linked keratoconic corneas, and healthy I genes with cold Medicine-Related Evaluation of keratoconus progression corneas These findings could help to Stevens-Johnson syndrome with severe (see page 551) monitor the success of crosslinking therapy. ocular complications in a Korean population (see page 573) Evaluation of keratoconus progres- Three-year outcomes of small incision HLA-A*02:06 and HLA-C*03:04 have sion should be performed by looking at lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ positive associations and HLA-C*03:03 multiple variables or indices consisting of keratomileusis (FS-LASIK) for myopia has negative association with cold medi- multiple parameters like the D-Value. An and myopic astigmatism (see page 565) cine related Stevens-Johnson syndrome increase in D-Value of 0.42/year showed In this study SMILE and FS-LASIK were and toxic epidermal necrolysis with the highest Youden-Index to identify eyes equally effective for myopic and astigmatic severe ocular complications in the Korean progressing. correction at 3 years after surgery. populations. http://bjo.bmj.com/ on September 30, 2021 by guest. Protected copyright.

ii Br J Ophthalmol April 2019 Vol 103 No 4