DOCSLIB.ORG

Proceedings of the 30Th International Conference on Animal Genetics ISAG 2006

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Proceedings of the 30Th International Conference on Animal Genetics ISAG 2006 Proceedings of the 30th International Conference on Animal Genetics ISAG 2006 ■ Biodiversity, the future pass through preservation ■ Porto Seguro, BA, Brazil, August 20-25, 2006 International Society for Animal Genetics ISBN 85-85584-02-5 Organized by: Colégio Brasileiro de Reprodução Animal Belo Horizonte, MG, Brazil Organizing Committee of ISAG 2006/Porto Seguro, Committees of the Society Brazil President :James Womack Denise A. Andrade de Oliveira – Escola de Veterinária Secretary : André Eggen da UFMG (Chair) Treasurer : Bertram Brenig Rômulo Cerqueira Leite - Escola de Veterinária da Executive Committee: Cecilia Penedo, Cynthia Bottema, UFMG (Vice-Chair) Peter Voegeli, Hiroshe Yasue, Noelle Cockett (Ex- Marcelo Y. Kuabara – Parentage Ltda (General Officio), Denise Oliveira (Ex-Officio) Secretary) Marc Henry – Escola de Veterinária da UFMG (Trasurer) ISAG Standing Committees : Antônio de Pinho Marques Jr - Escola de Veterinária da 1. Cattle Molecular Markers and Parentage Testing UFMG Committee (Marie-Yvonne Boscher) Eunice de Faria Lopes – CBRA 2. Equine Genetics and Thoroughbred Parentage Testing Standardization Committee (E. Gus Cothran) 3. Applied Genetics in Sheep and Goats Committee Scientific Committee (Liliana Di Stasio) 4. Deer Gene Mapping Committee (Loren C. Skow) Abel Ponce de Leon - University of Minnesota, USA 5. Applied Genetics Committee of Companying Célia R. Quirino – Universidade Estadual do Norte Animals (Hein van Haeringen) Fluminense, Brazil. 6. Bovine Leucocyte Antigen Standing Committee Craig Beattie – University of Nevada, USA (George C. Russell) David L. Adelson – Texas A & M University, USA 7. Dog Lymphocyte Antigen Nomenclature Committee Dino di Berardino – Università degli Studi di Napoli (Lorna Kennedy) Federico II, Italy. 8. Avian Immunogenetics Committee (Janet Fulton) Eduardo Casas – USDA, USA 9. Cattle, Sheep and Goat Gene Mapping Committee Ernest Bailey – University of Kentucky, USA (Eduardo Casas) Frank Nicholas – University of Sydney, Australia 10. Dog Genome Mapping Committee (Kathryn Gary Rohrer – USDA, USA Graves) 11. Horse Genome Mapping Committee (Matthew Binns) Gus E. Cothran - Texas A & M University, USA 12. Pig Gene Mapping and Applied Genetics Committee Harris A. Lewin – University of Illinois, USA (Gary Rohrer) Henner Simianer – University of Goettingen, Germany 13. Poultry Gene Mapping Committee (Richard James M. Reece – Iowa State Univerity, USA Crooijmans) Jonathan E. Beever - University of Illinois, USA 14. Rabbit Gene Mapping Committee (Hein van Lith) José Bento S. Ferraz – Universidade de São Paulo, 15. Comparative Genomics Committee (Christopher Brazil. Tuggle) Kathryn Graves - University of Kentucky, USA 16. ISAG-FAO Advisory Group on Animal Genetic Lawrence Schook - University of Illinois, USA Diversity (Henner Simianer) Liliana Di Stasio - Università degli Studi di Torino, 17. Domestic Animal Genome Sequencing Committee Italy. (Lawrence Schook) Lorna Kennedy – University of Manchester, USA 18. Genetics of Immune Response Committee (Herman Luiz Lehmann Coutinho - Universidade de São Paulo, Raadsma) Brazil. 19. Swine Lymphocyte Antigen Committee (Douglas Shirley Ellis – Institute of Animal Health, UK Smith) Sree Kanthaswamy – University of California, USA 20. Comparative MHC Steering Committee (Shirley Ellis) Telhisa Hasegawa – JRA Equine Research Institute, 21. Animal Forensic Genetics Committee (Sree Japan Kanthaswamy) Contents Acknowledgment 3 1 Time Table 4 2 Program Plenary Sessions 5 Workshops 5 Oral Presentation of Selected Posters 12 Best Posters 13 3 Guest Chairs and Speakers 14 4 Abstracts Plenary Sessions 16 Workshops 19 Section A: Polymorphism and Biodiversity 22 Section B: Structural Genomic 36 Section C: Functional Genomics 62 Section D: Genetic Markers and Selection 84 Section E: Genome Technologies and Bioinformatics 102 Author index 106 5 List of Participants 115 Acknowledgment Dear friends and colleagues, We are very proud to host, for the first time in South America, the ISAG Conference. Specially here in Porto Seguro, one of the most hospitable Brazilian cities. We believe that you will have an unique opportunity, to know our culture and to exchange knowledge. The Organizing Committee wishes to thanks to all the individuals who helped us to achieve our objectives. Our sincere gratitude to the members of the scientific committee; to the plenary sessions, workshops and poster oral presentation chairpersons; the invited speakers and volunteer students. It is also the proper time for our gratefulness to the ISAG Executive Committee and all the ISAG members, who gave us, six years ago, during the conference in Minneapolis, U.S.A., a vote of confidence to organize this conference in Brazil. We also address our thanks to all the sponsors and exhibitors, whose support was essential for the realization of this event. Finally, our gratitude to the Brazilian College of Animal Reproduction (CBRA) staff, especially to Rômulo Cerqueira Leite, Maria Helena Chaves Silva, Simone Martins Monteiro, Marta Lúcia Oliveira Paiva, Eunice Faria Lopes, Marc Roger Jean Marie Henry e Antônio de Pinho Marques Júnior. On behalf of the Local Organizing Committee, Denise A. A. de Oliveira Marcelo Y. Kuabara Chair of ISAG 2006 General Secretary of ISAG 2006 Veterinary College, Universidade Federal de Minas Gerais Parentage LTDA. - 3 - Timetable of the Conference SUNDAY MON TUE WED THU FRI TIME 20-Aug-06 21-Aug-06 22-Aug-06 23-Aug-06 24-Aug-06 25-Aug-06 conf.tour 09:00 - 10:00 registration registration registration registration registration plenary animal plenary plenary cattle,sheep, domes immune 10:00 - 11:00 session 1 forensic session 2 session 3 goat gene t anim respons map gen e 11:00 - 12:00 seq ) 12:00 - 13:30 lunch lunch lunch lunch lunch lunch sessions pig gene appl gen poster horse poultry appl poster exhibition poster ISAG gen cattle,sheep, dog 13:30 - 14:30 map companion viewing gen gen gen viewing business goat gene gen animals mounting (all poster map map sheep meeting map map 14:30 - 15:30 goat 15:30 - 16:15 coffee break coffee break coffee break coffee break coffee break poster exhibition poster exhibition poster pig gene equine cattle ISAG- horse poultry comp comparative poster oral animal poster oral 16:15 - 17:15 map genetics molecular FAO gen gen genomics MHC presentatio forensic presentatio parentage parentage map map Cancelled n n 17:15 - 18:15 poster exhibition poster by the Chair welcome removing poster 18:15 - 19:15 reception 19:15 - 19:45 banquet 20:00 - 24:00 - 4 - Plenary Sessions Plenary Session 1: Biodiversity research: understanding the past, designing the future. August 20 (Sunday) 10:00-12:00 at Room 1 Chair: Henner Simianer, Inst.Animal Breeding & Genetics, Germany. The value of diversity rational concepts on how to asses diversity and develop global strategies to maintain it Martin Weitzman, Department of Economics, Harvard University, USA The history of the molecular diversity of livestock genetic resources: overview of our current knowledge Olivier Hanotte, International Livestock Research Institute, Kenya. Conservation genetics in a megadiversity country Fabrício R. Santos, Universidade Federal de Minas Gerais, Brazil. Plenary Session 2: Genomics and biodiversity. August 22 (Tuesday) 10:00-12:00 at Room 1 Chair: Harris A. Lewin, Department of Animal Sciences, University of Illinois, USA. Evolution Highway: large-scale analysis of vertebrate chromosomal evolution Denis Larkin, University of Illinois, USA. Combined technologies of assisted reproduction, cloning and the state-of-the-art of microarray analysis Jerry Yang, University of Connecticut, USA. Gene Identification Signature (GIS) analysis: a novel cloning technology using paired-end 5’ and 3’ tags to characterize mammalian transcriptome and genome Ruan Yijun, Genome Institute of Singapore, Singapore. Plenary Session 3: The functional genome. August 24 (Thursday) 10:00-12:00 at Room 1 Chair: Luiz Lehmann Coutinho, Department of Animal Science, Universidade de São Paulo, Brazil. Functions of microRNAs in C. elegans development and human cancer Eric Miska, Dept. Biochemistry, University of Cambridge, United Kingdom. • Genome adaptations of TRIM5 for retroviral defense in ruminants – Timothy Smith, USDA, USA. Physiological genomics Identifying genes for endoparasite resistance Allan Crawford, AgResearch, New Zealand. Workshops Workshop 1: Pig Gene Mapping and Applied Genetics. August 20 (Sunday) 13:30-15:30/Coffee break/16:15-18:15 at Room 1 Chair: Gary Rohrer, USDA-MARC, Clay Center, NE, USA Session 1: Status of Pig Genomic Research • Welcome [5’] • Overview of Pig QTL and Identification of QTN [25’] • An integrated RH map of the porcine genome with more than 5000 anchoring points on the human genome provides a framework for the sequencing of the pig [B520] Denis Milan, INRA/Laboratoire de Génétique Cellulaire, France • Construction of pig gene catalog: determination and application of porcine full-length cDNA sequences [B283] Hirohide Uenishi, National Institute of Agrobiological Sciences, Japan • Genetics of porcine Geneexpression Christian Bendixen, Danish Institute of Agricultural Sciences, Denmark • Sequencing the Pig Genome using a BAC by BAC approach [B404] Sean Humphray, The Wellcome Trust Sanger Institute, UK - 5 - Session 2: Highlights of Posters • Improved annotation of the porcine Affymetrix GeneChip(R) and functional comparison to QIAGEN-NRSP8 oligonucleotide array data [E246] Oliver Couture, Iowa State University, Ames, USA • Microsatellite and chromosome Y sequence
Load more

Recommended publications
  • FEI Regulations for Equestrian Events at the Olympic Games
    FEI Fédération Equestre Internationale FEI Regulations for Equestrian Events at the Olympic Games 24th Edition, Effective for the Olympic Games Tokyo 2020 23 July-8 August 2021 Fédération Equestre Internationale t +41 21 310 47 47 HM King Hussein I Building f +41 21 310 47 60 Chemin de la Joliette 8 www.fei.org 1006 Lausanne Switzerland Printed in Switzerland Copyright © 2018 Fédération Equestre Internationale 7 December 2018 Updated on 21 December 2018 Updated on 30 December 2018 Updated on 18 April 2019 Updated on 3 October 2019 Updated on 24 June 2020 Updated on 16 June 2021 FEI Regulations for Equestrian Events Tokyo (JPN) 2020 Olympic Games TABLE OF CONTENTS THE FEI CODE OF CONDUCT FOR THE WELFARE OF THE HORSE .................................. 4 CHAPTER I GENERAL .................................................................................................. 6 ARTICLE 600 – INTRODUCTION .................................................................................................. 6 ARTICLE 601 –COMPETITIONS .................................................................................................... 6 ARTICLE 602 – COMPETITION SCHEDULE .................................................................................... 7 ARTICLE 603 – CLASSIFICATION, MEDALS & PRIZES..................................................................... 7 ARTICLE 604 – QUOTA .............................................................................................................. 8 ARTICLE 605 - AP ALTERNATE ATHLETES, RESERVE HORSES,
    [Show full text]
  • Identification of the Binding Partners for Hspb2 and Cryab Reveals
    Brigham Young University BYU ScholarsArchive Theses and Dissertations 2013-12-12 Identification of the Binding arP tners for HspB2 and CryAB Reveals Myofibril and Mitochondrial Protein Interactions and Non- Redundant Roles for Small Heat Shock Proteins Kelsey Murphey Langston Brigham Young University - Provo Follow this and additional works at: https://scholarsarchive.byu.edu/etd Part of the Microbiology Commons BYU ScholarsArchive Citation Langston, Kelsey Murphey, "Identification of the Binding Partners for HspB2 and CryAB Reveals Myofibril and Mitochondrial Protein Interactions and Non-Redundant Roles for Small Heat Shock Proteins" (2013). Theses and Dissertations. 3822. https://scholarsarchive.byu.edu/etd/3822 This Thesis is brought to you for free and open access by BYU ScholarsArchive. It has been accepted for inclusion in Theses and Dissertations by an authorized administrator of BYU ScholarsArchive. For more information, please contact [email protected], [email protected]. Identification of the Binding Partners for HspB2 and CryAB Reveals Myofibril and Mitochondrial Protein Interactions and Non-Redundant Roles for Small Heat Shock Proteins Kelsey Langston A thesis submitted to the faculty of Brigham Young University in partial fulfillment of the requirements for the degree of Master of Science Julianne H. Grose, Chair William R. McCleary Brian Poole Department of Microbiology and Molecular Biology Brigham Young University December 2013 Copyright © 2013 Kelsey Langston All Rights Reserved ABSTRACT Identification of the Binding Partners for HspB2 and CryAB Reveals Myofibril and Mitochondrial Protein Interactors and Non-Redundant Roles for Small Heat Shock Proteins Kelsey Langston Department of Microbiology and Molecular Biology, BYU Master of Science Small Heat Shock Proteins (sHSP) are molecular chaperones that play protective roles in cell survival and have been shown to possess chaperone activity.
    [Show full text]
  • Evaluating and Comparing Descendants of Stallions from the Dark Ronald Line in Czech Warmblood Breeding According to Basic Body Measurements
    11 1RYHPEHU 2020, Brno, Czech Republic Evaluating and comparing descendants of stallions from the Dark Ronald line in Czech Warmblood breeding according to basic body measurements Zuzana Kubikova, Iva Jiskrova, Barbora Kubistova Department of Animal Breeding Mendel University in Brno Zemedelska 1, 613 00 Brno CZECH REPUBLIC [email protected] Abstract: The aim of this study was to evaluate the influence of the Dark Ronald stallion line in the breeding of the Czech Warmblood. To evaluate the importance of the line, the offspring of stallions authorized to act as stud horses in the breeding of the Czech Warmblood were used. The values of the basic body measurements of their offspring (SHW, THW, ChC and CBC) were used to evaluate the quality of the stallions. A total of 6 breeding stallions were compared: two representatives of the Holsteiner horse (2765 CASSILIUS, 2666 PORTER), one Russian Holsteiner (2782 BALLAST), one Slovak Warmblood (794 CORSÁR), one Dutch Warmblood (2745 OSCAR) and one representative of the Zweibrücker breed (662 CARBIDO). The group for comparison consisted of 284 offspring of the Czech Warmblood breed from these sires. Evaluation by the GLM model detected statistically significant differences between the basic body measurements of the individual groups of offspring. The influence of the dams on the basic body measurements of offspring was taken into account by a graphical comparison of the massiveness and boniness indices. It was found that the stallion 2782 BALLAST significantly affects the massiveness of his offspring, but the dam has a greater influence on boniness than the sire. Furthermore, it was found that mares are statistically significantly more massive than stallions, but that they have a smaller cannon bone circumference.
    [Show full text]
  • List of Horse Breeds 1 List of Horse Breeds
    List of horse breeds 1 List of horse breeds This page is a list of horse and pony breeds, and also includes terms used to describe types of horse that are not breeds but are commonly mistaken for breeds. While there is no scientifically accepted definition of the term "breed,"[1] a breed is defined generally as having distinct true-breeding characteristics over a number of generations; its members may be called "purebred". In most cases, bloodlines of horse breeds are recorded with a breed registry. However, in horses, the concept is somewhat flexible, as open stud books are created for developing horse breeds that are not yet fully true-breeding. Registries also are considered the authority as to whether a given breed is listed as Light or saddle horse breeds a "horse" or a "pony". There are also a number of "color breed", sport horse, and gaited horse registries for horses with various phenotypes or other traits, which admit any animal fitting a given set of physical characteristics, even if there is little or no evidence of the trait being a true-breeding characteristic. Other recording entities or specialty organizations may recognize horses from multiple breeds, thus, for the purposes of this article, such animals are classified as a "type" rather than a "breed". The breeds and types listed here are those that already have a Wikipedia article. For a more extensive list, see the List of all horse breeds in DAD-IS. Heavy or draft horse breeds For additional information, see horse breed, horse breeding and the individual articles listed below.
    [Show full text]
  • A Computational Approach for Defining a Signature of Β-Cell Golgi Stress in Diabetes Mellitus
    Page 1 of 781 Diabetes A Computational Approach for Defining a Signature of β-Cell Golgi Stress in Diabetes Mellitus Robert N. Bone1,6,7, Olufunmilola Oyebamiji2, Sayali Talware2, Sharmila Selvaraj2, Preethi Krishnan3,6, Farooq Syed1,6,7, Huanmei Wu2, Carmella Evans-Molina 1,3,4,5,6,7,8* Departments of 1Pediatrics, 3Medicine, 4Anatomy, Cell Biology & Physiology, 5Biochemistry & Molecular Biology, the 6Center for Diabetes & Metabolic Diseases, and the 7Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202; 2Department of BioHealth Informatics, Indiana University-Purdue University Indianapolis, Indianapolis, IN, 46202; 8Roudebush VA Medical Center, Indianapolis, IN 46202. *Corresponding Author(s): Carmella Evans-Molina, MD, PhD ([email protected]) Indiana University School of Medicine, 635 Barnhill Drive, MS 2031A, Indianapolis, IN 46202, Telephone: (317) 274-4145, Fax (317) 274-4107 Running Title: Golgi Stress Response in Diabetes Word Count: 4358 Number of Figures: 6 Keywords: Golgi apparatus stress, Islets, β cell, Type 1 diabetes, Type 2 diabetes 1 Diabetes Publish Ahead of Print, published online August 20, 2020 Diabetes Page 2 of 781 ABSTRACT The Golgi apparatus (GA) is an important site of insulin processing and granule maturation, but whether GA organelle dysfunction and GA stress are present in the diabetic β-cell has not been tested. We utilized an informatics-based approach to develop a transcriptional signature of β-cell GA stress using existing RNA sequencing and microarray datasets generated using human islets from donors with diabetes and islets where type 1(T1D) and type 2 diabetes (T2D) had been modeled ex vivo. To narrow our results to GA-specific genes, we applied a filter set of 1,030 genes accepted as GA associated.
    [Show full text]
  • Prediction of Meiosis-Essential Genes Based Upon the Dynamic Proteomes Responsive to Spermatogenesis
    bioRxiv preprint doi: https://doi.org/10.1101/2020.02.05.936435; this version posted February 6, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC 4.0 International license. Prediction of meiosis-essential genes based upon the dynamic proteomes responsive to spermatogenesis Kailun Fang1,2,3,8, Qidan Li3,4,5,8, Yu Wei2,3,8, Jiaqi Shen6,8, Wenhui Guo3,4,5,7,8, Changyang Zhou2,3,8, Ruoxi Wu1, Wenqin Ying2, Lu Yu1,2, Jin Zi5, Yuxing Zhang3,4,5, Hui Yang2,3,9*, Siqi Liu3,4,5,9*, Charlie Degui Chen1,3,9* 1. State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China. 2. State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Institute of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China. 3. University of the Chinese Academy of Sciences, Beijing 100049, China. 4. CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China. 5. BGI Genomics, BGI-Shenzhen, Shenzhen 518083, China. 6. United World College Changshu China, Jiangsu 215500, China. 7. Malvern College Qingdao, Shandong, 266109, China 8.
    [Show full text]
  • A Dominant Mutation in RPE65 Identified by Whole-Exome
    A Dominant Mutation in RPE65 Identified by Whole-Exome Sequencing Causes Retinitis Pigmentosa with Choroidal Involvement Peter Humphries, Sara J Bowne, Marian M Humphries, Lori S Sullivan, Paul F Kenna, Lawrence Cs Tam, Anna-Sophia Kiang, Matthew Campbell, George M Weinstock, Daniel C Koboldt, et al. To cite this version: Peter Humphries, Sara J Bowne, Marian M Humphries, Lori S Sullivan, Paul F Kenna, et al.. A Dominant Mutation in RPE65 Identified by Whole-Exome Sequencing Causes Retinitis Pigmentosa with Choroidal Involvement. European Journal of Human Genetics, Nature Publishing Group, 2011, 10.1038/ejhg.2011.86. hal-00649449 HAL Id: hal-00649449 https://hal.archives-ouvertes.fr/hal-00649449 Submitted on 8 Dec 2011 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Edited manuscript for European Journal of Human Genetics April 4th 2011. “A Dominant Mutation in RPE65 Identified by Whole-Exome Sequencing Causes Retinitis Pigmentosa with Choroidal Involvement” Sara J. Bowne1*, Marian M. Humphries2*, Lori S. Sullivan1*, Paul F. Kenna2,3*, Lawrence C.S. Tam2, Anna Sophia Kiang2, Matthew Campbell2, George M. Weinstock4, Daniel C. Koboldt4, Li Ding4, Robert S. Fulton4, Erica J. Sodergren4, Denis Alman2, Sophia Millington-Ward2, Arpad Palfi2, Alex McKee2, Susan H.
    [Show full text]
  • NICU Gene List Generator.Xlsx
    Neonatal Crisis Sequencing Panel Gene List Genes: A2ML1 - B3GLCT A2ML1 ADAMTS9 ALG1 ARHGEF15 AAAS ADAMTSL2 ALG11 ARHGEF9 AARS1 ADAR ALG12 ARID1A AARS2 ADARB1 ALG13 ARID1B ABAT ADCY6 ALG14 ARID2 ABCA12 ADD3 ALG2 ARL13B ABCA3 ADGRG1 ALG3 ARL6 ABCA4 ADGRV1 ALG6 ARMC9 ABCB11 ADK ALG8 ARPC1B ABCB4 ADNP ALG9 ARSA ABCC6 ADPRS ALK ARSL ABCC8 ADSL ALMS1 ARX ABCC9 AEBP1 ALOX12B ASAH1 ABCD1 AFF3 ALOXE3 ASCC1 ABCD3 AFF4 ALPK3 ASH1L ABCD4 AFG3L2 ALPL ASL ABHD5 AGA ALS2 ASNS ACAD8 AGK ALX3 ASPA ACAD9 AGL ALX4 ASPM ACADM AGPS AMELX ASS1 ACADS AGRN AMER1 ASXL1 ACADSB AGT AMH ASXL3 ACADVL AGTPBP1 AMHR2 ATAD1 ACAN AGTR1 AMN ATL1 ACAT1 AGXT AMPD2 ATM ACE AHCY AMT ATP1A1 ACO2 AHDC1 ANK1 ATP1A2 ACOX1 AHI1 ANK2 ATP1A3 ACP5 AIFM1 ANKH ATP2A1 ACSF3 AIMP1 ANKLE2 ATP5F1A ACTA1 AIMP2 ANKRD11 ATP5F1D ACTA2 AIRE ANKRD26 ATP5F1E ACTB AKAP9 ANTXR2 ATP6V0A2 ACTC1 AKR1D1 AP1S2 ATP6V1B1 ACTG1 AKT2 AP2S1 ATP7A ACTG2 AKT3 AP3B1 ATP8A2 ACTL6B ALAS2 AP3B2 ATP8B1 ACTN1 ALB AP4B1 ATPAF2 ACTN2 ALDH18A1 AP4M1 ATR ACTN4 ALDH1A3 AP4S1 ATRX ACVR1 ALDH3A2 APC AUH ACVRL1 ALDH4A1 APTX AVPR2 ACY1 ALDH5A1 AR B3GALNT2 ADA ALDH6A1 ARFGEF2 B3GALT6 ADAMTS13 ALDH7A1 ARG1 B3GAT3 ADAMTS2 ALDOB ARHGAP31 B3GLCT Updated: 03/15/2021; v.3.6 1 Neonatal Crisis Sequencing Panel Gene List Genes: B4GALT1 - COL11A2 B4GALT1 C1QBP CD3G CHKB B4GALT7 C3 CD40LG CHMP1A B4GAT1 CA2 CD59 CHRNA1 B9D1 CA5A CD70 CHRNB1 B9D2 CACNA1A CD96 CHRND BAAT CACNA1C CDAN1 CHRNE BBIP1 CACNA1D CDC42 CHRNG BBS1 CACNA1E CDH1 CHST14 BBS10 CACNA1F CDH2 CHST3 BBS12 CACNA1G CDK10 CHUK BBS2 CACNA2D2 CDK13 CILK1 BBS4 CACNB2 CDK5RAP2
    [Show full text]
  • Quantitative Genetic Analysis of Melanoma and Grey Level in Lipizzan Horses
    7th World Congress on Genetics Applied to Livestock Production, August 19-23, 2002, Montpellier, France QUANTITATIVE GENETIC ANALYSIS OF MELANOMA AND GREY LEVEL IN LIPIZZAN HORSES I. Curik1, M. Seltenhammer2 and J. Sölkner3 1Animal Science Department, Faculty of Agriculture, University of Zagreb, Croatia 2Clinic of Surgery and Ophthalmology, University of Veterinary Medicine Vienna, Austria 3Department of Livestock Science, University of Agricultural Sciences Vienna, Austria INTRODUCTION Changes of coat colour in which the "dark (non-grey)" colour present in foals is progressively replaced by grey is a known phenomenon in horses. A similar process is present in humans. The grey coat colour is inherited as a dominant trait and is the characteristic, although not exclusive, colour for some horse breeds (Bowling, 2000). The Lipizzan horse, originally bred for show and parade at the Imperial Court in Vienna, is among those breeds. Unfortunately, melanomas (skin tumours) are more prevalent in grey than in non-grey horses (e.g. Seltenhammer, 2000). The causative relationship for this positive association as well as the molecular basis for both traits (melanoma and grey level) are not known (Rieder, 1999 ; Seltenhammer, 2000). The inheritance of coat colour in horses has been always studied from a qualitative view (Sponenberg, 1996 ; Bowling, 2000). In the present study we quantified the grey level (shade) and estimated the proportion of additive genetic component (heritability in the narrow sense) of this trait. Further, we estimated the genetic relationship between melanoma stages and grey level as well as the additive inheritance of melanoma stages. MATERIAL AND METHODS Horses. Data for this study was collected from 351 grey Lipizzan horses of four national studs (Djakovo – Croatia ; 64 horses, Piber – Austria ; 160 horses, Szilvesvarad – Hungary ; 67 horses and Topol'cianky – Slovakia ; 60 horses).
    [Show full text]
  • Homozygous Tobiano and Homozygous Black Could Be Winners for Your Breeding Program, If You Know How to Play Your Cards
    By IRENE STAMATELAKYS Homozygous tobiano and homozygous black could be winners for your breeding program, if you know how to play your cards. L L I T S K C O T S N N A Y S E T R U O C n poker, a pair is not much to brag gets one of the pair from the sire and the in equine color genetics. If your goal about. Two pairs are just a hair bet - other of the pair from the dam.” is a black foal, and you’ve drawn the ter. But in equine color genetics, a Every gene has an address—a spe - Agouti allele, you’re out of luck. pair—or, even better, two—could cific site on a specific chromosome. be one of the best hands you’ll ever We call this address a locus—plural The Agouti effect hold. We’re talking about a sure bet— being loci. Quite often, geneticists use Approximately 20 percent of horses a pair of tobiano or black genes. the locus name to refer to a gene. registered with the APHA are bay. If Any Paint breeder will tell you that When a gene comes in different you also include the colors derived producing a quality foal that will forms, those variations are called alle - from bay—buckskin, dun, bay roan bring in top dollar is a gamble. In this les. For example, there is a tobiano and perlino—almost one-quarter of business, there are no guarantees. But allele and a non-tobiano allele. Either registered Paints carry and express the what if you could reduce some of the one can occur at the tobiano locus, Agouti allele, symbolized by an upper - risk in your breeding program as well but each chromosome can only carry case A.
    [Show full text]
  • Innate Immune Activity Is Detected Prior to Seroconversion in Children with HLA-Conferred Type 1 Diabetes Susceptibility
    2402 Diabetes Volume 63, July 2014 Henna Kallionpää,1,2,3 Laura L. Elo,1,4 Essi Laajala,1,3,5,6 Juha Mykkänen,1,3,7,8 Isis Ricaño-Ponce,9 Matti Vaarma,10 Teemu D. Laajala,1 Heikki Hyöty,11,12 Jorma Ilonen,13,14 Riitta Veijola,15 Tuula Simell,3,7 Cisca Wijmenga,9 Mikael Knip,3,16,17,18 Harri Lähdesmäki,1,3,5 Olli Simell,3,7,8 and Riitta Lahesmaa1,3 Innate Immune Activity Is Detected Prior to Seroconversion in Children With HLA-Conferred Type 1 Diabetes Susceptibility Diabetes 2014;63:2402–2414 | DOI: 10.2337/db13-1775 The insult leading to autoantibody development in chil- signatures. Genes and pathways related to innate immu- dren who will progress to develop type 1 diabetes (T1D) nity functions, such as the type 1 interferon (IFN) re- has remained elusive. To investigate the genes and sponse, were active, and IFN response factors were molecular pathways in the pathogenesis of this disease, identified as central mediators of the IFN-related tran- we performed genome-wide transcriptomics analysis on scriptional changes. Importantly, this signature was a unique series of prospective whole-blood RNA samples detected already before the T1D-associated autoanti- from at-risk children collected in the Finnish Type 1 bodies were detected. Together, these data provide Diabetes Prediction and Prevention study. We studied a unique resource for new hypotheses explaining T1D 28 autoantibody-positive children, out of which 22 pro- biology. gressed to clinical disease. Collectively, the samples PATHOPHYSIOLOGY covered the time span from before the development of autoantibodies (seroconversion) through the diagnosis of By the time of clinical diagnosis of type 1 diabetes (T1D), diabetes.
    [Show full text]
  • Diversity and Effective Population Size of Four Horse Breeds from Microsatellite DNA Markers in South-Central Mexico
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Newcastle University E-Prints Vázquez-Armijo JF, Parra-Bracamonte GM, Velazquez MA, Sifuentes-Rincón AM, Tinoco-Jaramillo JS, Ambriz-Morales P, Arellano-Vera W, Moreno- Medina VR. Diversity and effective population size of four horse breeds from microsatellite DNA markers in South-Central Mexico. Archives Animal Breeding 2017, 60(2), 137-143. Copyright: © Author(s) 2017. This work is distributed under the Creative Commons Attribution 3.0 License. DOI link to article: https://doi.org/10.5194/aab-60-137-2017 Date deposited: 20/06/2017 This work is licensed under a Creative Commons Attribution 3.0 Unported License Newcastle University ePrints - eprint.ncl.ac.uk Arch. Anim. Breed., 60, 137–143, 2017 https://doi.org/10.5194/aab-60-137-2017 Open Access © Author(s) 2017. This work is distributed under the Creative Commons Attribution 3.0 License. Archives Animal Breeding Diversity and effective population size of four horse breeds from microsatellite DNA markers in South-Central Mexico José Fernando Vázquez-Armijo1, Gaspar Manuel Parra-Bracamonte2, Miguel Abraham Velazquez3, Ana María Sifuentes-Rincón2, José Luis Tinoco-Jaramillo4, Pascuala Ambriz-Morales2, Williams Arellano-Vera2, and Victor Ricardo Moreno-Medina2 1Centro Universitario UAEM Temascaltepec, Universidad Autónoma del Estado de México (UAEM). Km. 67.5 Carretera Federal Toluca-Tejupilco, Código Postal 51300, Temascaltepec, Estado de México, Mexico 2Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Boulevard del Maestro, esquina Elías Piña, Colonia Narciso Mendoza, Código Postal 88710, Reynosa, Tamaulipas, Mexico 3School of Agriculture, Food & Rural Development, Newcastle University, Newcastle upon Tyne NE1 7RU, UK 4Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México.
    [Show full text]