Phytochemical Constituents of Genus Nepeta
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Characteristic Odor Components of Essential Oil from Scutellaria Laeteviolacea
Journal of Oleo Science Copyright ©2013 by Japan Oil Chemists’ Society J. Oleo Sci. 62, (1) 51-56 (2013) Characteristic Odor Components of Essential Oil from Scutellaria laeteviolacea Mitsuo Miyazawa1＊ , Machi Nomura1, 2, Shinsuke Marumoto1 and Kiyoshige Mori2 1 Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University 3-4-1 Kowakae, Higashiosakashi, Osaka 577-8502, Japan 2 Ohsugi Pharmaceutical Co., Ltd, 1-1-2 Abeno-ku Tennoji-cho minami, Osaka 545-0002, Japan Abstract: The essential oils from aerial parts of Scutellaria laeteviolacea was analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The characteristic odor components were also detected in the oil using gas chromatography-olfactometry (GC-O) analysis and aroma extraction dilution analysis (AEDA). As a result, 100 components (accounting for 99.11 %) of S. laeteviolacea, were identified. The major components of S. laeteviolacea oil were found to be 1-octen-3-ol (27.72 %), germacrene D (21.67 %),and β-caryophyllene (9.18 %). The GC-O and AEDA results showed that 1-octen-3-ol, germacrene D, germacrene B, and β-caryophyllene were the most characteristic odor components of the oil. These compounds are thought to contribute to the unique flavor of this plant. Key words: essential oil, Scutellaria laeteviolacea, 1-octen-3-ol, aroma extraction dilution analysis, relative flavor activity 1 INTRODUCTION particular, gas chromatography-olfactometry（GC-O）analy- Scutellaria laeteviolacea is a perennial plant belonging sis, including aroma extract dilution analysi（s AEDA）and to the family Lamiaceae. In recent years, this aromatic CharmAnalysis, has been used to identify the potent odor- plant of the aerial parts has been used as a herb in Japan. -
Phytochemical Composition of Essential Oils Isolated
Pharmacophore 2013, Vol. 4 (6), 181-211 USA CODEN: PHARM7 ISSN 2229-5402 Pharmacophore (An International Research Journal) Available online at http://www.pharmacophorejournal.com/ Review Article PHYTOCHEMICAL COMPOSITION OF ESSENTIAL OILS ISOLATED FROM DIFFERENT SPECIES OF GENUS NEPETA OF LABIATAE FAMILY: A REVIEW Ajay Sharma and Damanjit Singh Cannoo* Department of Chemistry, Sant Longowal Institute of Engineering and Technology, Longowal, Sangrur, Punjab-148106, India ABSTRACT Aromatic and medicinal plants have been regarded as foremost source of secondary metabolites (SMs). These SMs (less toxic and biodegradable) and their derivatives have been recognised as versatile source of biologically active drugs. The most of the drugs used in present medicinal system have direct or indirect relation with secondary metabolites. So, during last few decades the interest has increased in the study of phytochemical composition of aforementioned plants to evaluate their prospective in modern medicinal system. Amongst various plant families which have been known for their medicinal and therapeutic values, Labiatae (Mint) family (Genus Nepeta) remains quite important. Essential oils extracted from various parts of species of above said genus have been a vital source of terpenoid and oxygenated terpenoid hydrocarbons especially sesquiterpene hydrocarbons and their oxygenated derivatives. These compounds have been known for their inherent biological activities viz. sedative, diaphoretic, feberifuge, expectorant, diuretic, stomach tonic, antispasmodic, antipyretics, anti-viral, anti-inflammatory, antimicrobial, fungicidal, insecticidal, insect repellent and antidote against snakes and scorpion bites etc. The present communication constitutes a review on the chemical composition of essential oils (only key constituents) extracted from genus Nepeta along with the details of their specific area of collection, height, specific time in a year, stage of plant collection, method used for extraction and technique of analysis. -
The Evolutionary Origins of the Cat Attractant Nepetalactone in Catnip
This is a repository copy of The evolutionary origins of the cat attractant nepetalactone in catnip. White Rose Research Online URL for this paper: https://eprints.whiterose.ac.uk/161043/ Version: Published Version Article: Lichman, Benjamin Robert orcid.org/0000-0002-0033-1120, Godden, Grant, Hamilton, John et al. (14 more authors) (2020) The evolutionary origins of the cat attractant nepetalactone in catnip. Science Advances. eaba0721. ISSN 2375-2548 https://doi.org/10.1126/sciadv.aba0721 Reuse This article is distributed under the terms of the Creative Commons Attribution-NonCommercial (CC BY-NC) licence. This licence allows you to remix, tweak, and build upon this work non-commercially, and any new works must also acknowledge the authors and be non-commercial. You don’t have to license any derivative works on the same terms. More information and the full terms of the licence here: https://creativecommons.org/licenses/ Takedown If you consider content in White Rose Research Online to be in breach of UK law, please notify us by emailing [email protected] including the URL of the record and the reason for the withdrawal request. [email protected] https://eprints.whiterose.ac.uk/ SCIENCE ADVANCES | RESEARCH ARTICLE BIOSYNTHESIS Copyright © 2020 The Authors, some The evolutionary origins of the cat attractant rights reserved; exclusive licensee nepetalactone in catnip American Association for the Advancement Benjamin R. Lichman1*, Grant T. Godden2, John P. Hamilton3, Lira Palmer4, of Science. No claim to 4 3† 3 3 original U.S. Government Mohamed O. Kamileen , Dongyan Zhao , Brieanne Vaillancourt , Joshua C. Wood , Works. -
Metabolic Changes of Aflatoxin B1 to Become an Active Carcinogen And
ome Re un se m a rc Im h Immunome Research Carvajal-Moreno M, Immunome Res 2015, 11:2 ISSN: 1745-7580 DOI: 10.4172/1745-7580.10000104 Review Article Open Access Metabolic Changes of Aflatoxin B1 to become an Active Carcinogen and the Control of this Toxin Magda Carvajal-Moreno Departamento de Botánica, Instituto de Biología, Universidad Nacional Autónoma de México. Ciudad Universitaria, Coyoacán, 04510 México DF Corresponding author: Magda Carvajal-Moreno, Departamento de Botánica, Instituto de Biología, Universidad Nacional Autónoma de México. Ciudad Universitaria, Coyoacán, 04510 México DF, Tel: +52 55 5622 1332; E-mail: [email protected] Received date: November 07, 2015; Accepted date: December 18, 2015; Published date: December 22, 2015 Copyright: © 2015 Carvajal-Moreno M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract Although aflatoxins are unavoidable toxins of food, many methods are available to control them, ranging from natural detoxifying methods to more sophisticated ones. The present review englobes the main characteristics of Aflatoxins as mutagens and carcinogens for humans, their physicochemical properties, the producing fungi, susceptible crops, effects and metabolism. In the metabolism of Aflatoxins the role of cytochromes and isoenzymes, epigenetics, glutathione-S-transferase enzymes, oncogenes and the role of aflatoxins -
PRE Evaluation Report for Nepeta Racemosa 'Walker's Low'
PRE Evaluation Report -- Nepeta racemosa 'Walker's Low' Plant Risk Evaluator -- PRE™ Evaluation Report Nepeta racemosa 'Walker's Low' -- Illinois 2017 Farm Bill PRE Project PRE Score: 2 -- Accept (low risk of invasiveness) Confidence: 72 / 100 Questions answered: 20 of 20 -- Valid (80% or more questions answered) Privacy: Public Status: Submitted Evaluation Date: September 13, 2017 This PDF was created on June 15, 2018 Page 1/17 PRE Evaluation Report -- Nepeta racemosa 'Walker's Low' Plant Evaluated Nepeta racemosa 'Walker's Low' Image by MBOT Page 2/17 PRE Evaluation Report -- Nepeta racemosa 'Walker's Low' Evaluation Overview A PRE™ screener conducted a literature review for this plant (Nepeta racemosa 'Walker's Low') in an effort to understand the invasive history, reproductive strategies, and the impact, if any, on the region's native plants and animals. This research reflects the data available at the time this evaluation was conducted. Summary Nepeta racemosa 'Walker's Low' poses a very low risk of invasion due to sterility. No evidence of significant dispersal by vegetative reproduction could be found. Though naturalized, the species Nepeta racemosa is not noted as invasive. General Information Status: Submitted Screener: Emily Russell Evaluation Date: September 13, 2017 Plant Information Plant: Nepeta racemosa 'Walker's Low' If the plant is a cultivar, how does its behavior differs from its parent's? 'Walker's Low' is sterile. Regional Information Region Name: Illinois Page 3/17 PRE Evaluation Report -- Nepeta racemosa 'Walker's Low' Climate Matching Map To answer four of the PRE questions for a regional evaluation, a climate map with three climate data layers (Precipitation, UN EcoZones, and Plant Hardiness) is needed. -
Trichomes Morphology and Density Analysis in Some Nepeta Species Of
ARTICLES Mediterranean Botany ISSNe 2603-9109 http://dx.doi.org/10.5209/MBOT.59574 Trichomes morphology and density analysis in some Nepeta species of Iran Seyed Mehdi Talebi1, Majid Ghorbani Nohooji2, Mahboobeh Yarmohammadi1, Narjes Azizi3, Alex Matsyura4 Received: 9 October 2017 / Accepted: 19 February 2018 Abstract. Nepeta are widely distributed worldwide and in different parts of Iran where seventy-nine species were registered. The essential oil of these aromatic plants, which accumulates and secrets by trichomes, has been used in medicinal and industrial products. In addition, these epidermal structures can be used as taxonomic traits. We examined the morphology and density of leaves trichomes of twelve Nepeta species using the light and scanning electron microscopes. Three types of indumentum are found in these species, which composed of two main types of glandular: peltate and capitate, and non- glandular; branched and unbranched trichomes. The number of the observed hairs differed between the studied species and analyses of variant test (ANOVA) showed significant variations among some of them. CA-joined plot proved that trichomes could be used as distinguishing characteristic. Therefore, we suggested that the type of indumentum and the most abundant glandular and non-glandular trichomes have high taxonomic value in species identification within the genus. Keywords: Nepeta species; trichomes; indumentum; glandular trichomes; non-glandular hairs. Análisis de la densidad y morfología de los tricomas en especies iraníes de Nepeta Resumen. El género Nepeta se distribuye ampliamente en todo el mundo y, más concretamente, en distintas partes de Irán donde se registran setenta y nueve especies. El aceite esencial de estas plantas aromáticas se acumula en tricomas y ha sido utilizado en productos industriales y también medicinales. -
Computer-Aided Chemotaxonomy and Bioprospecting Study of Diterpenes of the Lamiaceae Family
molecules Article Computer-Aided Chemotaxonomy and Bioprospecting Study of Diterpenes of the Lamiaceae Family Andreza Barbosa Silva Cavalcanti, Renata Priscila Costa Barros, Vicente Carlos de Oliveira Costa, Marcelo Sobral da Silva, Josean Fechine Tavares , Luciana Scotti and Marcus Tullius Scotti * Post-Graduate Program in Natural Synthetic Bioactive Products, Federal University of Paraiba, João Pessoa 58051-900, Paraíba, Brazil; [email protected] (A.B.S.C.); [email protected] (R.P.C.B.); [email protected] (V.C.d.O.C.); [email protected] (M.S.d.S.); [email protected] (J.F.T.); [email protected] (L.S.) * Correspondence: [email protected]; Tel.: +55-83-998690415 Received: 4 October 2019; Accepted: 27 October 2019; Published: 30 October 2019 Abstract: Lamiaceae is one of the largest families of angiosperms and is classified into 12 subfamilies that are composed of 295 genera and 7775 species. It presents a variety of secondary metabolites such as diterpenes that are commonly found in their species, and some of them are known to be chemotaxonomic markers. The aim of this work was to construct a database of diterpenes and to use it to perform a chemotaxonomic analysis among the subfamilies of Lamiaceae, using molecular descriptors and self-organizing maps (SOMs). The 4115 different diterpenes corresponding to 6386 botanical occurrences, which are distributed in eight subfamilies, 66 genera, 639 different species and 4880 geographical locations, were added to SistematX. Molecular descriptors of diterpenes and their respective botanical occurrences were used to generate the SOMs. In all obtained maps, a match rate higher than 80% was observed, demonstrating a separation of the Lamiaceae subfamilies, corroborating with the morphological and molecular data proposed by Li et al. -
Volatile Chemical Constituents of Nepeta Raphanorhiza Benth Growing in Kashmir Valley. Tauheeda Hassan1,*, Shakeel-U-Rehman2*, Bilal A
Tauheeda Hassan and Shakeel-u-Rehma et al. / Journal of Pharmacy Research 2011,4(9),3128-3129 Research Article Available online through ISSN: 0974-6943 www.jpronline.info Volatile Chemical Constituents of Nepeta raphanorhiza Benth growing in Kashmir valley. Tauheeda Hassan1,*, Shakeel-u-Rehman2*, Bilal A. Bhat3, Manzoor A.Rather2,Khursheed A. Bhat2, Abdul S. Shawl 2, Ghulam H. Dar1 1 Department of Botany, University of Kashmir, Srinagar-190006, India. 2 Natural Product Chemistry Division, Indian Institute of Integrative Medicine (CSIR), Srinagar-190005, India. 3Department of Zoology, University of Kashmir, Srinagar - 190006, India. Received on: 28-06-2011; Revised on: 15-07-2011; Accepted on:11-08-2011 ABSTRACT The essential oil composition of the aerial parts of N. raphanorhiza is reported for the first time. Capillary GC & GC-MS analysis of the essential oil led to the identification of 16 components accounting for 97.5% of the total oil composition .Sesquiterpene hydrocarbons dominated the oil composition accounting for 65.3 % followed by monoterpenes hydrocarbons constituting 1 9.5 % of the total o il composition. The major components were (Z) -ß- farnesene (49.2%), d- 3-carene (12.3%), a-bisabolene (9.4%) and germacrene-d-4-ol (5.8%). Keywords: Nepeta raphanorhiza, Lamiaceae, GC, GC-MS, (Z)-ß- farnesene, d-3-carene, a-bisabolene. 1. INTRODUCTION Nepeta is a multiregional genus of the family Lamiaceae comprising about 250 and head space analyzer using a fused silica capillary Column (30m x 0.32 mm, species distributed mainly in Southwest & central Asia, Europe, North Africa film thickness 0.25ìm) Coated with dimethyl polysiloxane (RTX-5). -
Male Meiotic Studies in 29 Species of Lamiaceae from Sirmaur District of Himachal Pradesh, India
© 2018 The Japan Mendel Society Cytologia 83(3): 235–243 Male Meiotic Studies in 29 Species of Lamiaceae from Sirmaur District of Himachal Pradesh, India Vijay Singh1, Raghbir Chand Gupta2, Kusum Sharma3, Vikas Sharma4, Manjul Sharma1 and Kuljit Kaur1* 1 Department of Botany, Mata Gujri College, Fatehgarh Sahib, Punjab140407, India 2 Department of Botany, Punjabi University, Patiala, Punjab 147002, India 3 Department of Botany, Shoolini Institute of Life Sciences and Business Management, Solan, Himachal Pradesh 173212, India 4 Department of Botany, DAV University, Jalandhar144012, India Received January 5, 2018; accepted March 2, 2018 Summary Lamiaceae is a requisite depository of many important medicinal herbs, distributed all over the world. The detailed meiotic studies, firstly are helpful in solving taxonomic and evolutionary enigmas and sec- ondly provide best chemotypes for further exploration and conservatory purposes. Male meiosis in 29 species of 54 populations belonging to the 18 genera of Lamiaceae has been undertaken for the first time from Sirmaur district of Himachal Pradesh falling in Western Himalayas. Euploid cytotypes are reported in Ajuga parviflora (n=8x=32), Nepeta eryostachys (n=4x=18) and N. graciliflora (n=4x=18). Besides, B-chromosomes in previ- ously known cytotypes of five species, A. bracteosa (n=32+0-2B), Leucas lanata (n=11+0-1B), Lycopus euro- peus (n=11+0-1B), Phlomis bracteosa (n=11+0-1B) and Vitex negundo (n=16+0-1B), are reported for the first time. A substantial amount of meiotic abnormalities in the form of chromatin stickiness, cytomixis, chromatin bridges and laggards are reported in the presently worked out population that leads to the high variability in the microsporogenesis, pollen grain size heterogeneity and ultimately, reduce pollen viability. -
Towards Understanding Mode-Of-Action of Traditional Medicines by Using in Silico Target Prediction
TOWARDS UNDERSTANDING MODE-OF-ACTION OF TRADITIONAL MEDICINES BY USING IN SILICO TARGET PREDICTION Siti Zuraidah Binti Mohamad Zobir Hughes Hall April 2017 This dissertation is submitted for the degree of Doctor of Philosophy of the University of Cambridge Supervisor: Dr Andreas Bender Name: SITI ZURAIDAH BINTI MOHAMAD ZOBIR Title: IN SILICO TARGET PREDICTION: TOWARDS UNDERSTANDING MODE-OF-ACTION OF TRADITIONAL MEDICINES Abstract Traditional medicines (TM) have been used for centuries to treat illnesses, but in many cases their modes-of-action (MOAs) remain unclear. Given the increasing data of chemical ingredients of traditional medicines and the availability of large-scale bioactivity data linking chemical structures to activities against protein targets, we are now in a position to propose computational hypotheses for the MOAs using in silico target prediction. The MOAs were established from supporting literature. The in silico target prediction, which is based on the “Molecular Similarity Principle”, was modelled via two models: a Naïve Bayes Classifier and a Random Forest Classifier. Chapter 2 discovered the relationship of 46 traditional Chinese medicine (TCM) therapeutic action subclasses by mapping them into a dendrogram using the predicted targets. Overall, the most frequent top three enriched targets/pathways were immune-related targets such as tyrosine-protein phosphatase non-receptor type 2 (PTPN2) and digestive system such as mineral absorption. Two major protein families, G-protein coupled receptor (GPCR), and protein kinase family contributed to the diversity of the bioactivity space, while digestive system was consistently annotated pathway motif. Chapter 3 compared the chemical and bioactivity space of 97 anti-cancer plants’ compounds of TCM, Ayurveda and Malay traditional medicine. -
INDEX SEMINUM 2020 No 20
BOTANICAL GARDEN OF ŠIAULIAI UNIVERSITY INDEX SEMINUM 2020 No 20 2020 1 BOTANICAL GARDEN OF ŠIAULIAI UNIVERSITY ______________________________________________________________________________ Phone: +370 659 93748 E-mail: [email protected] Web: http://bs.su.lt/ Facebook: https://www.facebook.com/SUbotanikossodas/ Authors: Virginija Aleknienė, Martynas Kazlauskas, Rimanta Vainorienė, Žydrūnė Valainytė, Rita Šulskienė. Cover design Karolis Grušas Photos are from the archyve of botanical garden 2 ŠIAULIAI UNIVERSITY BOTANICAL GARDEN ŠIAULIAI AREA. Šiauliai is a city of Northern Lithuania. It counts its years from the Battle of Saulė which took place in 1236. Šiauliai is the fourth largest city by its population. Population: 106 400. HISTORY. Šiauliai University Botanical Garden was established in 1997 at the former site of Agrobiological Station of Šiauliai University. Total area of the garden is 6.54 ha. Since 2003 Botanical Garden of Šiauliai University is a member of Botanic Gardens Conservation International, Planta Europa Network, Association of Botanic Gardens in the Baltic Sea Region, Botanical Gardens of the Baltic Countries and the Association of Lithuanian University Botanic Gardens (LUBSA). Since 2005 the Botanic Garden is a member of International Network of Phenological Gardens of Europe (IPG). There is a Club of Botanic Garden Friends at the Botanical Garden. The Garden exchanges seeds with more than 300 botanical gardens of the world. Director: dr. Martynas Kazlauskas. Fields of research: • research on plant biodiversity ex situ and in situ, • research on introduction and acclimatization of ornamental plants, • phenological observations. Other activities: • ex situ conservation, • educational activities at the Botanical Garden, • organization of events at the Botanical Garden. COLLECTIONS OF THE BOTANICAL GARDEN. -
Scutellaria Barbata in Traditional Chinese Medicine and Western Research Geyang Tao University of Connecticut - Storrs, [email protected]
University of Connecticut OpenCommons@UConn Honors Scholar Theses Honors Scholar Program Spring 4-22-2016 Current Therapeutic Role and Medicinal Potential of Scutellaria barbata in Traditional Chinese Medicine and Western Research Geyang Tao University of Connecticut - Storrs, [email protected] Marcy J. Balunas University of Connecticut - Storrs, [email protected] Follow this and additional works at: https://opencommons.uconn.edu/srhonors_theses Part of the Alternative and Complementary Medicine Commons, Integrative Medicine Commons, Natural Products Chemistry and Pharmacognosy Commons, and the Oncology Commons Recommended Citation Tao, Geyang and Balunas, Marcy J., "Current Therapeutic Role and Medicinal Potential of Scutellaria barbata in Traditional Chinese Medicine and Western Research" (2016). Honors Scholar Theses. 481. https://opencommons.uconn.edu/srhonors_theses/481 Current Therapeutic Role and Medicinal Potential of Scutellaria barbata in Traditional Chinese Medicine and Western Research Geyang Tao Advisor, Marcy J. Balunas, Ph.D. Department of Pharmaceutical Sciences School of Pharmacy Honors Program University of Connecticut, Storrs, CT 06269 Abstract Ethnopharmacological relevance: Scutellaria barbata is a common herb in Traditional Chinese Medicine (TCM) most often used to treat cancer. S. barbata has been found to exhibit efficacy both in vitro and in vivo on a variety of cancer types. Similarly encouraging results have been shown in patients with metastatic breast cancer from Phase Ia and Ib clinical trials. This study aims to elucidate the current use of S. barbata by TCM practitioners and in current Western research. Materials and Methods: Semi-structured interviews were conducted with fifteen TCM practitioners in Beijing and Nanjing, China to understand their clinical use of S. barbata.