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Volume4 Issue4(2) Volume 4, Issue 4(2), April 2015 International Journal of Multidisciplinary Educational Research Published by Sucharitha Publications 8-21-4,Saraswathi Nivas,Chinna Waltair Visakhapatnam – 530 017 Andhra Pradesh – India Email: [email protected] Website: www.ijmer.in Editorial Board Editor-in-Chief Dr.K. Victor Babu Faculty, Department of Philosophy Andhra University – Visakhapatnam - 530 003 Andhra Pradesh – India EDITORIAL BOARD MEMBERS Prof. S.Mahendra Dev Prof. Fidel Gutierrez Vivanco Vice Chancellor Founder and President Indira Gandhi Institute of Development Escuela Virtual de Asesoría Filosófica Research Lima Peru Mumbai Prof. Igor Kondrashin Prof.Y.C. Simhadri The Member of The Russian Philosophical Vice Chancellor, Patna University Society Former Director The Russian Humanist Society and Expert of Institute of Constitutional and Parliamentary The UNESCO, Moscow, Russia Studies, New Delhi & Formerly Vice Chancellor of Dr. Zoran Vujisiæ Benaras Hindu University, Andhra University Rector Nagarjuna University, Patna University St. Gregory Nazianzen Orthodox Institute Universidad Rural de Guatemala, GT, U.S.A Prof. (Dr.) Sohan Raj Tater Former Vice Chancellor Singhania University, Rajasthan Prof.U.Shameem Department of Zoology Andhra University Visakhapatnam Prof.K.Sreerama Murty Department of Economics Dr. N.V.S.Suryanarayana Andhra University - Visakhapatnam Dept. of Education, A.U. Campus Vizianagaram Prof. K.R.Rajani Department of Philosophy Dr. Momin Mohamed Naser Andhra University – Visakhapatnam Department of Geography Institute of Arab Research and Studies Prof. P.D.Satya Paul Cairo University, Egypt Department of Anthropology Andhra University – Visakhapatnam I Ketut Donder Depasar State Institute of Hindu Dharma Prof. Josef HÖCHTL Indonesia Department of Political Economy University of Vienna, Vienna & Prof. Roger Wiemers Ex. Member of the Austrian Parliament Professor of Education Austria Lipscomb University, Nashville, USA Prof. Alexander Chumakov Dr.B.S.N.Murthy Chair of Philosophy Department of Mechanical Engineering Russian Philosophical Society GITAM University –Visakhapatnam Moscow, Russia N.Suryanarayana (Dhanam) Department of Philosophy Dr.Ton Quang Cuong Andhra University Dean of Faculty of Teacher Education Visakhapatnam University of Education, VNU, Hanoi Dr.S.V Lakshmana Rao Prof. Chanakya Kumar Coordinator Department of Computer Science A.P State Resource Center University of Pune,Pune Visakhapatnam Prof. Djordje Branko Vukelic Dr.S.Kannan Department for Production Engineering Department of History University of Novi Sad, Serbia Annamalai University Annamalai Nagar, Chidambaram Prof.Shobha V Huilgol Department of Pharmacology Dr. Barada Prasad Bhol Off- Al- Ameen Medical College, Bijapur Registrar, Purushottam Institute of Engineering & Technology Prof.Joseph R.Jayakar Sundargarh, Odisha Department of English GITAM University Dr.E. Ashok Kumar Hyderabad Department of Education North- Eastern Hill University, Shillong Prof.Francesco Massoni Department of Public Health Sciences Dr.K.Chaitanya University of Sapienza, Rome Department of Chemistry Nanjing University of Science and Prof.Mehsin Jabel Atteya Technology Al-Mustansiriyah University People’s Republic of China College of Education Department of Mathematics, Iraq Dr.Merina Islam Department of Philosophy Prof. Ronato Sabalza Ballado Cachar College, Assam Department of Mathematics University of Eastern Philippines, Philippines Dr. Bipasha Sinha S. S. Jalan Girls’ College Dr.Senthur Velmurugan .V University of Calcutta, Calcutta Librarian Kalasalingam University Dr. K. John Babu Krishnankovil Tamilnadu Department of Journalism & Mass Comm Central University of Kashmir, Kashmir ® © Editor-in-Chief, IJMER Typeset and Printed in India www.ijmer.in IJMER, Journal of Multidisciplinary Educational Research, concentrates on critical and creative research in multidisciplinary traditions. This journal seeks to promote original research and cultivate a fruitful dialogue between old and new thought. C O N T E N T S Volume 4 Issue 4(2) April 2015 S. Page No No 1. Association analysis of Col9A1, Col9A2 ,Col9A3, 1 Aggrecan and TNF-α gene polymorphisms with early onset of Disc Herniation in Indian population K. Rajsekar, N. Narayanasamy, M. Kuhar, S. Vaishya, S.Rajasekaran and N. Devaraj 2. Impact and Analysis of Natural Hazards and Disasters 38 in Andhra Pradesh and Telangana N. Sreedhara Naidu and M. Krishna Naidu 3. River Pollution and its Awareness among Students in 61 Higher Secondary Level in Chandannagar, Hooghly District and Environmental Education Mridula Das 4. Development of An Emotional Response Inventory for 79 Gender Discrimination Experiences of Females Kumaranayake A.R 5. Water Balance and Irrigation Development of the 95 Rayalaseema Region, Andhra Pradesh, India K.Somanna and M.Sambasiva Rao 6. An Overview on Corporate Planning in India 127 K.Chandrasekhara Rao 7. Weaker Sections and Reservations: An Over View 134 T.Sreenu 8. Pain and Persecution; Interpreting Women’s Experience 146 in the Select Play of Mahasweta Devi ‘BAYEN’ Bathina Rajesh Kumar 9. Who Feels Lonelier? A Comparative Analysis 156 Anjana Bhattacharjee 10. Data Encryption using Square Grid Transposition and 172 Key Wrapping with RSA A.V.Ramana, Chandana A, Swarna M, Krishna Priya J and Suresh M 11. Participative Management in Cement Industries of 185 Odisha Barada Prasad Bhol 12. Child Labour in India: A Study on Visakhapatnam Zone 200 M.Gopi 13. Quantitative Fuzzy Topological Relation of Spatial 214 Objects to Compute Interior, Boundary and Exterior by Induced Fuzzy Topology H.C. Chamuah and B.C. Chetia 14. Gandhi's Concept of Peace Education and Its Ethical 228 Perspectives S. N. Rao 15. Loneliness in Relation to Self-Concept of Adolescents 234 with and without Siblings Anjali Puri and Sukhwant Bajwa 16. Desire of the Son in ‘The Legends of The Punjab’ 246 Harneet Kaur 17. Transfer of Learning to the Students through the 255 Means of Technology Madhava Kumar Kothapalli 18. Study of Computer Phobia Among B.Ed. College 266 Teachers in Jaipur District Mohit Dixit 19. Vidhyarthi Ke Jivan Me Shiksha Ka Mahatva 277 Shri Manish Jain 20. mRrjiwohZ jkT;ksa esa efgykvksa ds fo:) fgalk 284 “kks/k Nk=k Dr. K. VICTOR BABU ISSN : 2277 – 7881 M.A.,M.A.,M.Phil.,Ph.D.,PDF, (D.Lit) Impact Factor :2.972(2015) Faculty of Philosophy and Religious Index Copernicus Value: 5.16 Studies & Editor-in-Chief International Journal of Multidisciplinary Educational Research (IJMER) & Sucharitha: A Journal of Philosophy and Religion Andhra University, Visakhapatnam Pin - 530 003 , Andhra Pradesh – India Editorial…… You will be happy to know that we have entered the fourth year of publication of IJMER, since its inception in April 2012. Focusing on many interdisciplinary subjects, the published papers are spreading the knowledge with fervent hope of upholding the holistic approach. With all my heart, I reiterate to echo my sincere feelings and express my profound thanks to each and every valued contributor. This journal continues to nurture and enhance the capabilities of one and all associated with it. We as a team with relentless efforts are committed to inspire the readers and achieve further progress. Aim is to sustain the tempo and improve. We acknowledge with pleasure that our readers are enjoying the publications of Sucharita Publishers. We solicit to receive ideas and comments for future improvements in its content and quality. Editor – in-Chief explicitly conveys his gratitude to all the Editorial Board members. Your support is our motivation. Best wishes to everyone. Dr.K.Victor Babu Editor-in-Chief SOCIAL SCIENCES, HUMANITIES, COMMERCE & MANAGEMENT, ENGINEERING & TECHNOLOGY, MEDICINE, SCIENCES, ART & DEVELOPMENT STUDIES, LAW www.ijmer.in INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY EDUCATIONAL RESEARCH ISSN : 2277-7881; IMPACT FACTOR - 2.972; IC VALUE:5.16 VOLUME 4, ISSUE 4(2), APRIL 2015 ASSOCIATION ANALYSIS OF COL9A1, COL9A2, COL9A3, AGGRECAN AND TNF-Α GENE POLYMORPHISMS WITH EARLY ONSET OF DISC HERNIATION IN INDIAN POPULATION K. Rajsekar N. Narayanasamy Dept of Biochemistry Dept of Biochemistry Sri Venkateswara College Sri Venkateswara College University of Delhi, Delhi University of Delhi, Delhi S. Vaishya M. Kuhar Neurosurgery Dept of Biochemistry Fortis Hospital Sri Venkateswara College New Delhi University of Delhi, Delhi S.Rajasekaran N. Devaraj Director Dept of Biochemistry Dept of Orthopaedics and Spine University of Madras, Chennai Ganga Hospital, Coimbatore,India Introduction The intervertebral disc is largely an avascular tissue stabilized by the extracellular matrix network. The intervertebral discs are complex structures that consist of a thick outer ring of fibrous cartilage termed the annulus fibrosus, which surrounds a more gelatinous core known as the nucleus pulposus; the nucleus pulposus is sandwiched inferiorly and superiorly by cartilage end-plates. The central nucleus pulposus contains collagen fibres, which are organised randomly1, and elastin fibres which are arranged radially 2 these fibres are embedded in a highly hydrated aggrecan-containing gel. This arrangement allows the discs to facilitate movement and flexibility within what would be an otherwise rigid spine. The most common and painful Intervertebral disc disease is herniated or prolapsed disc. In these cases the discs bulge or rupture (either partially or totally) posteriorly or posterolaterally, and press on the nerve roots in the spinal canal3. The vertebral region more prone to herniation is the lumbar
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