Peter Bickel's Royal Decoration
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Front Matter
Cambridge University Press 978-0-521-14577-0 - Probability and Mathematical Genetics Edited by N. H. Bingham and C. M. Goldie Frontmatter More information LONDON MATHEMATICAL SOCIETY LECTURE NOTE SERIES Managing Editor: Professor M. Reid, Mathematics Institute, University of Warwick, Coventry CV4 7AL, United Kingdom The titles below are available from booksellers, or from Cambridge University Press at www.cambridge.org/mathematics 300 Introduction to M¨obiusdifferential geometry, U. HERTRICH-JEROMIN 301 Stable modules and the D(2)-problem, F. E. A. JOHNSON 302 Discrete and continuous nonlinear Schr¨odingersystems, M. J. ABLOWITZ, B. PRINARI & A. D. TRUBATCH 303 Number theory and algebraic geometry, M. REID & A. SKOROBOGATOV (eds) 304 Groups St Andrews 2001 in Oxford I, C. M. CAMPBELL, E. F. ROBERTSON & G. C. SMITH (eds) 305 Groups St Andrews 2001 in Oxford II, C. M. CAMPBELL, E. F. ROBERTSON & G. C. SMITH (eds) 306 Geometric mechanics and symmetry, J. MONTALDI & T. RATIU (eds) 307 Surveys in combinatorics 2003, C. D. WENSLEY (ed.) 308 Topology, geometry and quantum field theory, U. L. TILLMANN (ed) 309 Corings and comodules, T. BRZEZINSKI & R. WISBAUER 310 Topics in dynamics and ergodic theory, S. BEZUGLYI & S. KOLYADA (eds) 311 Groups: topological, combinatorial and arithmetic aspects, T. W. MULLER¨ (ed) 312 Foundations of computational mathematics, Minneapolis 2002, F. CUCKER et al (eds) 313 Transcendental aspects of algebraic cycles, S. MULLER-STACH¨ & C. PETERS (eds) 314 Spectral generalizations of line graphs, D. CVETKOVIC,´ P. ROWLINSON & S. SIMIC´ 315 Structured ring spectra, A. BAKER & B. RICHTER (eds) 316 Linear logic in computer science, T. EHRHARD, P. -
ZCWPW1 Is Recruited to Recombination Hotspots by PRDM9
RESEARCH ARTICLE ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair Daniel Wells1,2†*, Emmanuelle Bitoun1,2†*, Daniela Moralli1, Gang Zhang1, Anjali Hinch1, Julia Jankowska1, Peter Donnelly1,2, Catherine Green1, Simon R Myers1,2* 1The Wellcome Centre for Human Genetics, Roosevelt Drive, University of Oxford, Oxford, United Kingdom; 2Department of Statistics, University of Oxford, Oxford, United Kingdom Abstract During meiosis, homologous chromosomes pair and recombine, enabling balanced segregation and generating genetic diversity. In many vertebrates, double-strand breaks (DSBs) initiate recombination within hotspots where PRDM9 binds, and deposits H3K4me3 and H3K36me3. However, no protein(s) recognising this unique combination of histone marks have been identified. We identified Zcwpw1, containing H3K4me3 and H3K36me3 recognition domains, as having highly correlated expression with Prdm9. Here, we show that ZCWPW1 has co-evolved with PRDM9 and, in human cells, is strongly and specifically recruited to PRDM9 binding sites, with higher affinity than sites possessing H3K4me3 alone. Surprisingly, ZCWPW1 also recognises CpG dinucleotides. Male Zcwpw1 knockout mice show completely normal DSB positioning, but persistent DMC1 foci, severe DSB repair and synapsis defects, and downstream sterility. Our findings suggest ZCWPW1 recognition of PRDM9-bound sites at DSB hotspots is critical for *For correspondence: synapsis, and hence fertility. [email protected] (DW); [email protected] (EB); [email protected] (SRM) †These authors contributed Introduction equally to this work Meiosis is a specialised cell division, producing haploid gametes essential for reproduction. Uniquely, during this process homologous maternal and paternal chromosomes pair and exchange Competing interests: The DNA (recombine) before undergoing balanced independent segregation. -
Obituary Notices Ronald Drayton Brown
Obituary notices Ronald Drayton Brown Died 31 October 2008, elected to Fellowship 1965 Ronald Drayton (Ron) Brown was born in Melbourne on 14 October 1927. He grew up as an only child in modest suburban circumstances in Prahran and did not come from a scientific or academic background. His father had achieved some distinction in amateur athletics. His secondary education was at Wesley College, to which he had won a scholarship. He excelled in mathematics and physics and was an interested reader of astronomy books. He was dux of the school in his final year and was awarded an exhibition in physics in the Victorian matriculation examinations. In his first undergraduate year at the University of Melbourne, he majored in physics and chemistry. In second year he dropped Ron Brown physics, despite scoring better results than in chemistry. While completing a chemistry major he also informally attended the lectures in third year physics and mathematics, without completing the examinations, ending up with an effective triple major for his BSc in 1946. In the days before it was possible to do a PhD anywhere in Australia, Ron began his research career as an MSc student in the Department of Chemistry at the University of Melbourne with Dr Francis Lahey as supervisor. His thesis topic was alkaloid products from Australian plants, particularly Acronychia baueri. He had chosen this project because it would involve some organic chemistry and some spectroscopy. He was attracted by the relationships between the structure of organic compounds and their spectra, and the use of these ideas in deducing the structure of newly isolated compounds. -
Elect New Council Members
Volume 43 • Issue 3 IMS Bulletin April/May 2014 Elect new Council members CONTENTS The annual IMS elections are announced, with one candidate for President-Elect— 1 IMS Elections 2014 Richard Davis—and 12 candidates standing for six places on Council. The Council nominees, in alphabetical order, are: Marek Biskup, Peter Bühlmann, Florentina Bunea, Members’ News: Ying Hung; 2–3 Sourav Chatterjee, Frank Den Hollander, Holger Dette, Geoffrey Grimmett, Davy Philip Protter, Raymond Paindaveine, Kavita Ramanan, Jonathan Taylor, Aad van der Vaart and Naisyin Wang. J. Carroll, Keith Crank, You can read their statements starting on page 8, or online at http://www.imstat.org/ Bani K. Mallick, Robert T. elections/candidates.htm. Smythe and Michael Stein; Electronic voting for the 2014 IMS Elections has opened. You can vote online using Stephen Fienberg; Alexandre the personalized link in the email sent by Aurore Delaigle, IMS Executive Secretary, Tsybakov; Gang Zheng which also contains your member ID. 3 Statistics in Action: A If you would prefer a paper ballot please contact IMS Canadian Outlook Executive Director, Elyse Gustafson (for contact details see the 4 Stéphane Boucheron panel on page 2). on Big Data Elections close on May 30, 2014. If you have any questions or concerns please feel free to 5 NSF funding opportunity e [email protected] Richard Davis contact Elyse Gustafson . 6 Hand Writing: Solving the Right Problem 7 Student Puzzle Corner 8 Meet the Candidates 13 Recent Papers: Probability Surveys; Stochastic Systems 15 COPSS publishes 50th Marek Biskup Peter Bühlmann Florentina Bunea Sourav Chatterjee anniversary volume 16 Rao Prize Conference 17 Calls for nominations 19 XL-Files: My Valentine’s Escape 20 IMS meetings Frank Den Hollander Holger Dette Geoffrey Grimmett Davy Paindaveine 25 Other meetings 30 Employment Opportunities 31 International Calendar 35 Information for Advertisers Read it online at Kavita Ramanan Jonathan Taylor Aad van der Vaart Naisyin Wang http://bulletin.imstat.org IMSBulletin 2 . -
Computational and Financial Econometrics (CFE 2016)
CFE-CMStatistics 2016 PROGRAMME AND ABSTRACTS 10th International Conference on Computational and Financial Econometrics (CFE 2016) http://www.cfenetwork.org/CFE2016 and 9th International Conference of the ERCIM (European Research Consortium for Informatics and Mathematics) Working Group on Computational and Methodological Statistics (CMStatistics 2016) http://www.cmstatistics.org/CMStatistics2016 Higher Technical School of Engineering, University of Seville, Spain 9 – 11 December 2016 c CFE and CMStatistics networks. All rights reserved. I CFE-CMStatistics 2016 ISBN 978-9963-2227-1-1 c 2016 - CFE and CMStatistics networks Technical Editors: Angela Blanco-Fernandez and Gil Gonzalez-Rodriguez. All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted, in any other form or by any means without the prior permission from the publisher. II c CFE and CMStatistics networks. All rights reserved. CFE-CMStatistics 2016 International Organizing Committee: Ana Colubi, Stella Hadjiantoni, M. Dolores Jimenez-Gamero, Erricos Kontoghiorghes, George Loizou and Herman Van Dijk. CFE 2016 Co-chairs: Peter Boswijk, Jianqing Fang, Alain Hecq, Michael Smith. CFE 2016 Programme Committee: Alessandra Amendola, Ansgar Belke, Monica Billio, Josep Lluis Carrion-i-Silvestre, Roberto Casarin, Veronika Czellar, Serge Darolles, Manfred Deistler, Jean-David Fermanian, Sylvia Fruehwirth-Schnatter, Marc Hallin, Matthew Harding, Jan Jacobs, Menelaos Karanasos, Daniel Kaufmann, Robert Kunst, Degui Li, Marco Lippi, Zudi Lu, Luis Filipe Martins, Gian Luigi Mazzi, Tucker McElroy, J Isaac Miller, Bent Nielsen, Yasuhiro Omori, Michael Owyang, Gareth Peters, Michael Pitt, Stephen Pollock, Tommaso Proi- etti, Artem Prokhorov, Anders Rahbek, Francesco Ravazzolo, Jeroen Rombouts, Eduardo Rossi, Christos Savva, Willi Semmler, Laura Spierdijk, Giuseppe Storti, Jonathan Stroud, Genaro Sucarrat, Jean-Pierre Ur- bain, Shaun Vahey, Helena Veiga, Carlos Velasco, Helga Wagner, Martin Wagner, Toshiaki Watanabe and Peter Winker. -
64914 Stats News May 2003
statistical society of australia incorporated newsletter May, 2003 Number 103 Registered by Australia Post Publication No. NBH3503 issn 0314-6820 New Year’s Honours for Professor Chris Heyde In the 2003 New Year’s Honours, a gifted schoolteacher sparked have two sons Neil and Eric. Chris’ Professor Chris Heyde was his interest in mathematics. After first job was as an Assistant Professor awarded Membership of the Order leaving school, he enrolled at at Michigan State University of Australia (AM). Such awards the University of Sydney, in 1964-5; in 1965 he moved to are not lightly offered: they are graduating with a First Class Sheffield and later Manchester, intended to recognize the Member’s Honours degree in Mathematics where he was appointed Special contribution to Australian society. in 1961, and receiving the University Lecturer in charge of the Statistical Chris has undoubtedly given much Medal. He won a Commonwealth Laboratory in 1967. He returned to to this country: a brief account of his Postgraduate Research Scholarship Australia in 1968 as a Reader in Ted contributions (apart from his well to the Australian National Hannan’s Department of Statistics known research) follows. University (ANU), and earned his at the ANU. Chris was born in Sydney on 20 PhD in Statistics from Pat Moran’s In 1975, he joined Joe Gani in the April 1939, and went to school at Department in 1965. He married CSIRO Division of Mathematics Barker College, Hornsby, where Elizabeth James later that year; they and Statistics (DMS), first as a Senior Principal Research Scientist, and then as Chief Research Scientist and Assistant Chief of the Division from 1977. -
Amstat News May 2011 President's Invited Column
May 2011 • Issue #407 AMSTATNEWS The Membership Magazine of the American Statistical Association • http://magazine.amstat.org Croatia Bosnia Serbia Herzegovina ThroughPeace Statistics ALSO: Meet Susan Boehmer, New IRS Statistics of Income Director Publications Agreement No. 41544521 Mining the Science out of Marketing Math Sciences in 2025 AMSTATNews May 2011 • Issue #407 Executive Director Ron Wasserstein: [email protected] Associate Executive Director and Director of Operations features Stephen Porzio: [email protected] 3 President’s Invited Column Director of Education Martha Aliaga: [email protected] 5 Pfizer Contributes to ASA's Educational Ambassador Program Director of Science Policy 5 TAS Article Cited in Supreme Court Case Steve Pierson: [email protected] 7 Writing Workshop for Junior Researchers to Take Place at JSM Managing Editor Megan Murphy: [email protected] 8 Meet Susan Boehmer, New IRS Statistics of Income Director Production Coordinators/Graphic Designers 10 Peace Through Statistics Melissa Muko: [email protected] 15 Statistics in Biopharmaceutical Research Kathryn Wright: [email protected] May Issue of SBR: A Festschrift for Gary Koch Publications Coordinator Val Nirala: [email protected] 16 Journal of the American Statistical Association March JASA Features ASA President’s Invited Address Advertising Manager Claudine Donovan: [email protected] 19 Technometrics Fingerprint Individuality Assessment Featured in May Issue Contributing Staff Members Pam Craven • Rosanne Desmone • Fay Gallagher • Eric Sampson Amstat News welcomes news items and letters from readers on matters of interest to the association and the profession. Address correspondence to Managing Editor, Amstat News, American Statistical Association, 732 North Washington Street, Alexandria VA 22314-1943 USA, or email amstat@ columns amstat.org. -
IMS Bulletin Volume 36, Issue 9: November 2007
Volume 36 • Issue 9 IMS Bulletin November 2007 Advising junior faculty on research IMS Bulletin Editor Xuming He writes: CONTENTS If there is one thing that all statisticians agree on today, it is the recognition that 1 How do we evaluate statistics has evolved from a mathematical sub-field to a cross-cutting scientific disci- research? pline. Along with this exciting evolution come new challenges to a new generation of 2 Members’ News: Debajyoti academic statisticians. Junior faculty members in the statistics departments or in math- Sinha; Peter Donnelly; ematical sciences departments are often unsure how their co-authored papers and/or Donald Gaver their interdisciplinary research will be evaluated for their promotion. Sometimes they receive conflicting advice from senior members of our profession who have developed 4–6 Evaluating research: responses their career in a very different environment. To stimulate discussion and debate that may eventually help build consensus in our 7 Journal news; Randy Sitter profession and help our junior faculty choose the best course for their career develop- 8 IMS awards; ment in today’s competitive academic world, the Bulletin sought opinions from senior Laha recipients’ comments mentors and department chairs on how 10 IMS Reception photos they would advise junior faculty on the following questions. 11 Awards and nominations 1. Should junior faculty members go 12 WNAR/IMS meeting report for quality at the cost of quantity for 13 Rick’s Ramblings: Chuck’s publications? Rule 2. Should they refrain from too much interdisciplinary work, which often 14 Terence’s Stuff: Letters leads to publication in non-statistical 15 SPA and IMS journal rates journals? 16 IMS Meetings 3. -
Statistics in the State Universities: Beginnings and Establishment C.C
International Statistical Institute, 55th Session 2005: Chris Heyde Statistics in the State Universities: Beginnings and Establishment C.C. Heyde Australian National University and Columbia University Introduction Statistics in the early colonial period in Australia (ie the first half of the nineteenth century) was almost entirely related to official data collection. But as universities were founded a broader range of scientific uses slowly opened up. Prior to Federation (1901), four universities had been estab- lished in the colonies. These were the universities of Sydney, established in 1850, Melbourne in 1853, Adelaide in 1874 and Tasmania in 1890. With Fed- eration the states replaced colonies and the four existing universities were soon joined by ones in the remaining state capitals, namely Queensland in 1909 and Western Australia in 1911. This article will principally focus on the developments which took place through these institutions. It was not till after the second world war that Australia had a burst of creation of more universities and there followed the Australian National University (1946), University of New South Wales (1949), University of New England (1954), Monash University (1958), Macquarie University (1964), University of New- castle (1965), Flinders University (1966), James Cook University (1970).... Teaching in Mathematics began at all the original universities soon after their inception. Statistics, however, came much later. As in the UK and USA it was the methodological developments of the 1920s and the immedi- ate success of their application, for example in agriculture, which spurred interest in the discipline. Statistics teaching had its beginnings in each of the Mathematics Departments, typically near the end of the 1920s or begin- ning of the 1930s, but also, and in some cases largely contemporaneously, in the Faculties of Economics and Agriculture. -
VOLUME 80 Titles in This Series
Statistical Inference from Stochastic Processes Proceedings of a Summer Research Conference held August 9-15,1987 AMERICAN MATHEMATICAL SOCIETY VOLUME 80 Titles in This Series http://dx.doi.org/10.1090/conm/080 Volume 1 Markov random fields and their 18· Fixed points and nonexpansive applications. Ross Kindermann and mappings. Robert C. Sine, Editor J. Laurie Snell 19 Proceedings of the Northwestern 2 Proceedings of the conference homotopy theory conference, on integration. topology, and Haynes R. Miller and Stewart B. geometry in linear spaces, Priddy, Editors William H. Graves, Editor 20 Low dimensional topology, 3 The closed graph and P-closed Samuel J. Lomonaco, Jr., Editor graph properties in general 21 Topological methods in nonlinear topology, T. R. Hamlett and functional analysis, S. P. Singh, l. l. Herrington S. Thomeier, and B. Watson, Editors 4 Problems of elastic stability and 22 Factorizations of b" ± 1. b = vibrations, Vadim Komkov, Editor 2, 3, 5, 6, 7,10. 5 Rational constructions of 11, 12 up to high powers. modules for simple Lie algebras. John Brillhart, D. H. Lehmer, George B. Seligman J. l. Selfridge, Bryant Tuckerman, and 6 Umbral calculus and Hopf algebras, S. S. Wagstaff. Jr. Robert Morris, Editor 23 Chapter 9 of Ramanujan's second 7 Complex contour integral notebook-Infinite series identities, representation of cardinal spline transformations. and evaluations, functions. Walter Schempp Bruce C. Berndt and Padmini T. Joshi 8 Ordered fields and real algebraic 24 Central extensions, Galois groups, geometry, D. W. Dubois and and ideal class groups of number T. Recio, Editors fields, A. Frohlich 9 Papers in algebra, analysis and 25 Value distribution theory and its statistics. -
Mathematical Sciences Meetings and Conferences Section
OTICES OF THE AMERICAN MATHEMATICAL SOCIETY Richard M. Schoen Awarded 1989 Bacher Prize page 225 Everybody Counts Summary page 227 MARCH 1989, VOLUME 36, NUMBER 3 Providence, Rhode Island, USA ISSN 0002-9920 Calendar of AMS Meetings and Conferences This calendar lists all meetings which have been approved prior to Mathematical Society in the issue corresponding to that of the Notices the date this issue of Notices was sent to the press. The summer which contains the program of the meeting. Abstracts should be sub and annual meetings are joint meetings of the Mathematical Associ mitted on special forms which are available in many departments of ation of America and the American Mathematical Society. The meet mathematics and from the headquarters office of the Society. Ab ing dates which fall rather far in the future are subject to change; this stracts of papers to be presented at the meeting must be received is particularly true of meetings to which no numbers have been as at the headquarters of the Society in Providence, Rhode Island, on signed. Programs of the meetings will appear in the issues indicated or before the deadline given below for the meeting. Note that the below. First and supplementary announcements of the meetings will deadline for abstracts for consideration for presentation at special have appeared in earlier issues. sessions is usually three weeks earlier than that specified below. For Abstracts of papers presented at a meeting of the Society are pub additional information, consult the meeting announcements and the lished in the journal Abstracts of papers presented to the American list of organizers of special sessions. -
Statisticians of the Centuries
springer.com C.C. Heyde, P. Crepel, S.E. Fienberg, E. Seneta, J. Gani (Eds.) Statisticians of the Centuries Statisticians of the Centuries aims to demonstrate the achievements of statistics to a broad audience, and to commemorate the work of celebrated statisticians. This is done through short biographies that put the statistical work in its historical and sociological context, emphasizing contributions to science and society in the broadest terms rather than narrow technical achievement. The discipline is treated from its earliest times and only individuals born prior to the 20th Century are included. The volume arose through the initiative of the International Statistical Institute (ISI), the principal representative association for international statistics (founded in 1885). Extensive consultations within the statistical community, and with prominent members of ISI in particular, led to the names of the 104 individuals who are included in the volume. The biographies were contributed by 73 authors from across the world. The editors are the well-known statisticians Chris Heyde and Eugene Seneta. Chris Heyde is Professor of Statistics at both Columbia University in New York and the Australian National University in Canberra. He is also Director of the Center for Applied Probability at Columbia. He has twice served as Vice President of the ISI, and also as President of the ISI's Bernoulli Society. Eugene Seneta is Professor of Mathematical Statistics at the University of Sydney and a Member of the 2001, XII, 500 p. ISI. His historical writings focus on 19th Century France and the Russian Empire. He has taught courses on the history of probability-based statistics in U.S.