Anti-PPAP2A (Internal) polyclonal antibody (CABT- B799) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Target PPAP2A

Immunogen Synthetic peptide

Isotype IgG

Source/Host Rabbit

Species Reactivity Human, Mouse, Zebrafish

Purification Protein A Purified Total IgG

Conjugate Unconjugated

Applications IHC, WB

Format Liquid

Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)

Size 100 μg

Buffer Phosphate buffered saline (PBS)

Preservative None

Storage Store at 4°C for short-term use. For longer periods of storage, aliquot and store at -20°C. Avoid repeat freeze-thaw cycles.

BACKGROUND

Introduction PPAP2A is a member of the phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by . This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of from extracellular space. The expression of PPAP2A is found to be regulated by androgen in a prostatic adenocarcinoma cell line.The protein encoded by this

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Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described.

Keywords PPAP2A;phosphatidic acid phosphatase type 2A; phosphate phosphohydrolase 1;LPP1;PAP 2a;PAP2a;PAP2-alpha;phosphatidic acid phosphatase 2a;lipid phosphate phosphohydrolase 1a;phosphatidate phosphohydrolase type 2a

GENE INFORMATION

Synonyms PAP2a2; LLP1a; PAP-2a; LPP1; PAP2alpha2; PAP2; PAP2a; PAPalpha1; PPAP2A; PAP 2a

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Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved