OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for TA322830

PPAP2A (PLPP1) Rabbit Polyclonal Antibody Product data:

Product Type: Primary Antibodies Applications: IHC, WB Recommended Dilution: ELISA: 1:2000-5000, WB: 1:500-2000, IHC: 1:25-100 Reactivity: Human, Mouse, Rat Host: Rabbit Isotype: IgG Clonality: Polyclonal Immunogen: Synthetic peptide corresponding to a region derived from 40-53 amino acids of human phosphatase type 2A Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol Concentration: lot specific Purification: Antigen affinity purification Conjugation: Unconjugated Storage: Store at -20°C as received. Stability: Stable for 12 months from date of receipt. Predicted Protein Size: 32 kDa Name: phospholipid phosphatase 1 Database Link: NP_003702 Entrez Gene 19012 MouseEntrez Gene 64369 RatEntrez Gene 8611 Human O14494 Background: The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol; and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by . This protein is an integral membrane glycoprotein; and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described.

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 2 PPAP2A (PLPP1) Rabbit Polyclonal Antibody – TA322830

Synonyms: LLP1a; LPP1; PAP-2a; PAP2; PPAP2A

Protein Families: Druggable Genome, Transmembrane Protein Pathways: Ether metabolism, Fc gamma R-mediated phagocytosis, Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, Sphingolipid metabolism

Product images:

Predicted band size: 32 kDa. Positive control: Human liver cancer tissue lysate. Recommended dilution: 1/500-2000

Predicted cell location: Cytoplasm. Positive control: Human breast cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin- embedded Human breast cancer tissue using PPAP2A antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification: x200)

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 2