SPSP 2013 Toronto Abstracts
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ASB M B Annual Meeting Highlights from the 2009
2010 ANNUAL MEETING, APRIL 24-28. ANAHEIM AWAITS! hlights fr ig om H June 2009 t h e 2 0 0 9 A S B M B A n n u al Meeting American Society for Biochemistry and Molecular Biology ANNUAL REVIEWS A Nonprofit Scientific Publisher INSIGHTFUL ANNUAL REVIEW OF TABLE OF CONTENTS BIOCHEMISTRY Without a License, or Accidents Waiting to Happen, E. Peter Geiduschek RESEARCH IN • A Journey in the World of DNA Rings and Beyond, James C. Wang BIOCHEMISTRY Vol. 78 • JUlY 2009 • The Biochemistry of Disease: Desperately Seeking Syzygy, John W. Kozarich • Biosynthesis of Phosphonic and Phosphinic Acid Natural STARTS WITH Editor: Products, William W. Metcalf, Wilfred A. van der Donk • New Antivirals and Drug Resistance, Peter M. Colman • Multidrug Resistance in Bacteria, Roger D. Kornberg ANNUAL Hiroshi Nikaido • Conformational Pathology of the Serpins: Themes, REVIEWS Stanford University School Variations, and Therapeutic Strategies, Bibek Gooptu, David A. Lomas of Medicine • Getting a Grip on Prions: Oligomers, Amyloids, and Pathological Membrane Interactions, Byron Caughey, Gerald S. Baron, Bruce Chesebro, Annual Review of Martin Jeffrey • RING Domain E3 Ubiquitin Ligases, Raymond J. Deshaies, Biochemistry, in publication Claudio A.P. Joazeiro • Regulation and Cellular Roles of Ubiquitin- since 1932, sets the standard Specific Deubiquitinating Enzymes, Francisca E. Reyes-Turcu, Karen H. Ventii, Keith D. Wilkinson • Recognition and Processing of Ubiquitin- for review articles in biological Protein Conjugates by the Proteasome, Daniel Finley • Degradation of chemistry and molecular biology. Activated Protein Kinases by Ubiquitination, Zhimin Lu, Tony Hunter • The Since its inception, these volumes Role of Ubiquitin in the NFκB Regulatory Pathways, Brian Skaug, Xiaomo have served as an indispensable Jiang, Zhijian J. -
Realism for Realistic People
Realism for Realistic People Author(s): Hasok Chang Source: Spontaneous Generations: A Journal for the History and Philosophy of Science, Vol. 9, No. 1 (2018) 31-34. Published by: The University of Toronto DOI: 10.4245/sponge.v9i1.27002 EDITORIALOFFICES Institute for the History and Philosophy of Science and Technology Room 316 Victoria College, 91 Charles Street West Toronto, Ontario, Canada M5S 1K7 [email protected] Published online at jps.library.utoronto.ca/index.php/SpontaneousGenerations ISSN 1913 0465 Founded in 2006, Spontaneous Generations is an online academic journal published by graduate students at the Institute for the History and Philosophy of Science and Technology, University of Toronto. There is no subscription or membership fee. Spontaneous Generations provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Focused Discussion Invited Paper Realism for Realistic People* Hasok Chang† Why should anyone care about the seemingly interminable philosophical debate concerning scientific realism? Shouldn’t we simply let go of it,in the spirit of Arthur Fine’s “natural ontological attitude” (NOA) (Fine 1986, chs. 7-8)? To a large extent I follow Fine, especially in relation to the endless arguments surrounding realist attempts to show that the impossible is somehow possible, that empirical science can really attain assured knowledge about what goes beyond experience. It is time to face the fact that we cannot know whether we have got the objective Truth about the World (even if such a formulation is meaningful). Realists go astray by persisting in trying to find a way around this fact, as do anti-realists in engaging with that obsession. -
Pages 459 To
459 University Organization Board of Trustees The dean of the Heller School for Social study abroad, international students and Policy and Management oversees the scholars, and student enrichment services), academic activities of the school and its Hiatt Career Center, research and planning, Under Massachusetts law, the Board of work in such policy areas as children, and student life (including athletics, Trustees is the governing body of the youth, families, health, mental health, chaplaincy, community service, health university. There are four faculty substance abuse, disabilities, aging, social services, intercultural center, judicial representatives and three student change, and economic inequalities. orientation, psychological counseling, representatives to the board who participate residence life, and student activities). in board meetings and have votes on the The dean of the Brandeis International several committees. The president of the Business School oversees the academic, The senior vice president for university, the chair of the Fellows, the professional, and development activities communications administers and executes president of the Brandeis National of the university’s second professional critical university-wide internal and Committee, and the president of the school. Research areas of the school external communications, overseeing the Alumni Association serve ex officio. The include economic policy, finance, global communications emergency response plan board annually elects an alumni term entrepreneurship, international business, and directing all crisis communications. trustee who serves a four-year term with regional economics integration, and trade Further, she is responsible for an integrated full voting privileges. and exports. marketing communications program that highlights Brandeis’s research The President accomplishments, academic excellence, The president, the chief executive officer of The Faculty Senate social justice mission, and scholarly the university, is appointed by the Board of contributions to the Jewish community. -
Understanding Perspectivism
This impressive collection is essential reading for appreciating the inevi- table contextualities of scientific knowledge. It explores how notions of “perspective” can illuminate the epistemic upshot of the sciences and how they are situated in their history, practices, representations, and sometimes competing aims, provocatively advancing debates about realism, pragma- tism, explanation, and modeling in the process, all through a wealth of cases from physics, biology, neuroscience, and medical science . —Anjan Chakravartty, University of Miami An excellent collection of essays on a topic rapidly establishing itself as an important interpretive programme in philosophy of science. One of the volume’s many merits consists in showing the diversity and versatil- ity of perspectivism while illustrating common features among its differ- ent varieties. The reader is thus provided an enormously rich foundation for evaluating the role of perspectivism in understanding science and its practices . —Margaret Morrison, University of Toronto Perspectivism is a fruitful metaphor for imagining alternatives to tradi- tional realism in philosophy of science. Massimi and McCoy have gath- ered ten essays which show how perspectivism is illuminating in areas such as molecular biology and measurement theory, and also explore the relationships between perspectivism and other recent accounts including pragmatism, structural realism, pluralism, and scientific modelling. There is an excellent balance of established and emerging scholars in the field. This volume is a superb, cutting-edge text to use in an advanced graduate seminar . —Miriam Solomon, Temple University Understanding Perspectivism This edited collection is the first of its kind to explore the view called perspectivism in the philosophy of science. The book brings together an array of essays that reflect on the methodological promises and scientific challenges of perspectivism in a variety of fields such as physics, biology, cognitive neuroscience, and cancer research, just for a few examples. -
2014-Program-For-Lecture-Gregory
OKLAHOMA SCHOOL OF SCIENCE AND MATHEMATICS Oklahoma stands out among other states in our dedication to providing OSSM an outstanding science and mathematics education to its gifted students at a time when our nation falls behind other countries in these areas. Senator Penny Williams Distinguished Lecture Series With just 22 classes graduated, OSSM alumni/alumnae are already Presents bringing substantial benefits to our state as they complete their degrees and move into their professions. “How Parkinson’s Disease Starts and •••••••••••••••••••••••• How It Might Be Stopped” • Eighty-five percent of OSSM alumni are remaining in scientific, technology, By engineering, and mathematics (STEM) fields for their careers! 2014 Capra Scholar • Of OSSM graduates now employed (many are still in undergraduate and graduate school or completing residencies in medical school), more than 60% GreGory A. PetSko, D.PHIl. are employed in Oklahoma. The fields of study and careers most chosen by OSSM graduates are engineering Arthur J. Mahon Professor of Neurology and Neuroscience and • Director, Helen and Robert Appel Alzheimer’s Disease Research Institute Weill Cornell Medical College (aerospace, biomedical, chemical, civil, computer, electrical, mechanical, Adjunct Professor of Biomedical Engineering Cornell University petroleum); medicine, medical research, and other health sciences; and other fields including computer science, technology, education, scientific research, Gyula and Katica Tauber Professor of Biochemistry and Chemistry, Emeritus Brandeis University business, and law. Adjunct Professor of Neurology Harvard Medical School Many OSSM alums are employed in many of Oklahoma’s finest corporations, Past-President, American Society for Biochemistry and Molecular Biology • President, International Union of Biochemistry and Molecular Biology hospitals and technical firms such as AT&T, Artificial Lift Company, Baptist Hospital, Benham Companies, Boeing, Chesapeake Energy, C. -
Hasok Chang Department of History and Philosophy of Science, University of Cambridge
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Apollo 1 Operational Coherence as the Source of Truth1 (version for publication, 14 February 2017) Hasok Chang Department of History and Philosophy of Science, University of Cambridge Abstract In this paper I seek to defend an epistemology that does not confine itself to the knowledge of propositions. The first section motivates this move, especially from the standpoint of the philosophy of science. The second section presents the notion of operational coherence as the key to understanding how knowledge resides in activities. The third section presents a proposal for making sense of truth on the basis of operational coherence. The final section briefly re- considers the relation between knowledge-as-ability and knowledge-as- information. 1. Knowledge beyond propositions The overall direction of this paper is to move beyond the propositional conception of knowledge. What I mean by that phrase is the widespread notion that knowledge (or at least the kind of knowledge that deserves the attention of epistemologists) consists in possessing the right sort of belief in the right sort of propositions.2 Without denying the importance of propositional knowledge, I want to pay attention to other aspects of what we commonly call knowledge, which cannot comfortably be fitted into a propositional framework. I will not pretend that the move I am making is a novel one, especially in this journal. 1 I would like to thank various members of the audience at the Aristotelian Society meeting of 9 January 2017 for helpful objections and suggestions, as well as encouragement. -
Biophysical Society 58Th Annual Meeting February 15–19, 2014 | San Francisco, California
ABSTRACT DEADLINE: OCTOBER 1, 2013 | EARLY REGISTRATION DEADLINE: JANUARY 8, 2014 Biophysical Society 58th Annual Meeting FEBRUARY 15–19, 2014 | SAN FRANCISCO, CALIFORNIA BIOPHYSICS OF CELL DIVISION AND National Lecturer SPATIAL RELATIONSHIPS Workshops Susan Biggins, Fred Hutchinson Cancer Workshops will be held on Sunday and Carlos Bustamante Research Center, Co-Chair Tuesday evenings. University of California, Berkeley Wallace Marshall, University of California, San Francisco, Co-Chair POLARIZABLE FORCE FIELDS FROM Daniel Fletcher, University of California, BIOMOLECULAR SIMULATIONS A Journey Through Cellular Processes: Berkeley One Molecule at a Time Matthieu Piel, Curie Institute, France Benoit Roux, University of Chicago, Co-Chair Alexander Mackerell, University FORCE GENERATION IN CELL AND of Maryland, Co-Chair TISSUE NETWORKS Vijay Pande, Stanford University Michael Sheetz, Columbia University, MOLECULAR BASIS FOR REGULATION Teresa Head-Gordon, University Co-Chair Symposia 2+ of California, Berkeley OF CA CHANNELS Clare Waterman, NHLBI, Co-Chair Stephen Long, Memorial Sloan- Symposia will be held Sunday through Alexander Bershadsky, Weizmann Kettering Cancer Center, Co-Chair SINGLE MOLECULE DYNAMICS USING Wednesday. Institute of Science, Israel FRET/LRET Amy Lee, University of Iowa, Co-Chair Frank Jülicher, Max Planck Institute for the Achillefs Kapanidis, University of Annette Dolphin, University College Physics of Complex Systems, Germany FORCE SENSING IN MUSCLE London, United Kingdom Oxford, United Kingdom, Co-Chair Mathias Gautel, -
Pragmatic Realism†
Revista de Humanidades de Valparaíso Año 4 / 2016 / 2do semestre / N° 8 Págs. 107 - 122 ISSN 0719-4234 / eISSN 0719-4242 Pragmatic Realism† Hasok Chang* Abstract In this paper I seek to articulate and develop Roberto Torretti’s advocacy of pragmatic realism. At the core of Torrietti’s view is a rejection of the notion that the truth of scientific theories consists in their correspondence to the world. I propose to understand correspondence in that sense as a metaphorical notion. I articulate a notion of pragmatist coherence, on the basis of which I make new coherence theories of truth and reality. Then it becomes possible to say that pragmatic realism consists in the pursuit of true knowledge of reality, in a way that is also consonant with Torretti’s pluralism. Keywords: pragmatism, realism, pluralism, coherence, truth, reality Realismo Pragmático Resumen En este trabajo intento articular y desarrollar la defensa que Roberto Torretti hace del realismo pragmático. En el núcleo de la visión de Torretti existe un rechazo a la idea de que la verdad de las teorías científicas consista en su correspondencia con el mundo. Propongo entonces entender la correspondencia como una noción metafórica. Articularé una noción de coherencia pragmática sobre la cual establezco una nueva teoría de la coherencia entre verdad y realidad. __________________En consecuencia, resultará posible afirmar que el realismo pragmático † Recibido: octubre 2016. This paper is partly based on a presentation entitled “Pragmatist Coherence as the Source of Truth and Reality,” given at the sixth biennial conference of the Society for Philosophy of Science in Practice (SPSP) on 17 June 2016 at Rowan University. -
Experimentally Demonstrated the Intrinsic Instability of the Fluorite-Type Zr Cation Network
0246110 Rta(i) 1 1,2 l,4 1,6 1,l 2 22 Rta(i) Figure 2. Temperature dependence of Zr-FTfor pure orthorhombic zirconia Figure 3 Temperature dependence of Zr-0 shell in tetragonal zirconia solid solution Our study has experimentally demonstrated the intrinsic instability of the fluorite-type Zr cation network. Coherent scattering beween Conclusions central Zr ion and distant cations is weaker and vibration modes of the Zr-cation network are It is found that, for all of zirconia solid softer in tetragonal zirconia than in monoclmic, solutions studied, the dopant-oxygen distances are orthorhombic, or stabilized cubic zirconia. In si@icantly ddferent from the Zr-0 distances. addition, the outer foux oxygens in the 8-fold The dopant-cation distances, on the other hand, coordinated Zr-0 polyhedron are only loosely are usually very close to the Zr-Zr distance, solutions. A bonded and are subject to very large static and confirming the formation of solid dynamic distortions. This effect is illustrated by general structural picture for zirconia solid the expanded portion of the Fourier transform solutions is one that places the dopant cations shown in Figure 3. randomly on tbe Zr sites in the cation network, but with distorted and sometimes very different Dopant Structure dopant-oxygen polyhedra surrounding these dopants. In the case of Ge4+ doping and Y-Nb We have also successfully performed co-doping, short-rangecation ordering has been EXAFS experiments at the dopant absorption suggested from our EXAFS results. edges for doped zirconia solid solutions. Dopants Based on the above structural information studied include the Ce-,Nb-, and Y-K edges as and other EXAFS results obtained from NSLS, well as Ce-LIn edge. -
Curriculum Vitae
1 GRANT FISHER Graduate School of Science and Technology Policy, Korea Advanced Institute of Science and Technology 291 Daehak-ro, Yuseong-Gu, Daejeon 34141 Republic of Korea Tel: +82-42-350-4855 Mobile: +82-(0)10-2800-4303 Email: [email protected] Research interests. Philosophy of science, ethics and governance of emerging technologies, history and philosophy of chemistry. Education. October 1999- University of Leeds Ph.D. in Philosophy September 2003 Specialization: Philosophy of Science, Philosophy of Chemistry Supervisor: Steven French October 1998- University of Leeds M.A. in History and Philosophy of Science September 1999 Pass with Distinction. September 1995- University College London B.Sc. (Honours) in History and Philosophy of Science, June 1998 University College London, 1998. Class I (First Class Honours). Academic appointments. August 2013-present Korea Advanced Institute of Science and Technology Associate Professor, Graduate School of Science and Technology Policy. August 2010-August 2013 Korea Advanced Institute of Science and Technology Associate Professor, Department of Humanities and Social Science; Adjunct Professor, Graduate School of Science and Technology Policy. August 2008-August 2010 Boğaziçi University Lecturer in Humanities (fixed term) June 2005-July 2008 University College London Research Fellow in Philosophy of Science, Department of Science & Technology Studies. Worked on the research project “Evidence in the Natural Sciences” (Project Leader: Hasok Chang) as part of the UCL Research Programme: “Evidence, Inference and Enquiry: Towards an Integrated Science of Evidence”. (Principle Investigator: Philip Dawid). September 2004-May 2005 University of Leeds Temporary Lecturer in Philosophy of Science, Department of 2 Philosophy. October 2003-June 2004 Durham University Temporary Lecturer in History of Science, Department of Philosophy. -
Water: the Long Road from Aristotelian Element to H2O Hasok Chang•
III CONFERÊNCIAS ALLEN DEBUS CIRCUMSCRIBERE 12 (2012): 1-15 Water: The long road from Aristotelian element to H2O Hasok Chang• Introduction In today’s science-based civilization, people tend to accept without question the most basic things that science tells us, except on certain controversial subjects such as evolution. This is the case even for people who do not know much science or like it very much. For example, anyone with even the slightest acquaintance with modern science knows and accepts that water is H2O. Yet it was a very difficult thing for scientists to learn. That is the subject of my recently published book, Is Water H2O? Evidence, Realism and Pluralism (Dordrecht: Springer, 2012). If we take a closer look at the basic items of scientific knowledge that we take so much for granted, almost always we find that they were achieved only with great difficulty, and only after some very challenging questions were resolved, or set aside without being resolved. These reflections bring us to the most basic question of epistemology: how do we know anything? More specifically, how can we be sure about what scientific theories tell us about unobservable entities? How can such theories be supported by evidence? These questions are at the core of the philosophical debates concerning scientific realism. Many general and abstract answers have been given to the realism question (and to similar questions in the philosophy of science), but I often do not find them convincing because they are not based on sufficient knowledge of how the acquisition and evaluation of scientific knowledge work out in practice. -
Cell Biology in Sudan
See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/290440842 Science on the Banks of the Nile: Cell Biology in Sudan Article · September 2014 READS 162 4 authors, including: Marmar A. El Siddig Adil Ali EL Hussein University of Khartoum University of Khartoum 40 PUBLICATIONS 25 CITATIONS 44 PUBLICATIONS 67 CITATIONS SEE PROFILE SEE PROFILE Sakina Yagi University of Khartoum 36 PUBLICATIONS 174 CITATIONS SEE PROFILE Available from: Marmar A. El Siddig Retrieved on: 17 May 2016 ASCB MARCH 2014 NEWSLETTER VOLUME 37, NUMBER 2 The ASCB in 2018 Page 3 ASCB Task Force to Explore Annual Meeting Reproducibility of Scientific Data Highlights The apparent irreproducibility of some published scientific Page 9 results is an issue of growing concern to industry and to the scientific community. It has begun to receive attention in the news media as well, and if one believes the popular press as MBoC Call for Papers much as 80% of scientific research cannot be reproduced. Is in Quantitative that really true? Does that apply to all research or just some Biology areas? These are just two of the questions a task force of the Page 36 ASCB’s Public Policy Committee (PPC) will attempt to answer as it conducts an in-depth analysis of the issue. If reports of widespread difficulty in reproducing published Inside research results are true, it is a problem that could threaten the scientific enterprise and undermine the authority of the COMPASS Outreach Awards 2 scientific community. In his charge to the task force, ASCB Executive Director’s Column 3 Executive Director Stefano Bertuzzi listed four potential causes for difficulties in reproducing results: DORA Panel Discussion 9 n A hyper-competitive culture that overemphasizes results BSCB Young Cell Biologist 10 n A bias in favor of positive results Young French Cell Biologists 11 Reproducibility, continued on p.17 Mark Winey Local Meeting Highlights 12 Nominate a Colleague for an ASCB Award! Deadline April 1.