DOCSLIB.ORG

Sheet1 Page 1 a Abamectin Acetazolamide Sodium Adenosine-5-Monophosphate Aklomide Albendazole Alfaxalone Aloe Vera Alphadolone A

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Sheet1 Page 1 a Abamectin Acetazolamide Sodium Adenosine-5-Monophosphate Aklomide Albendazole Alfaxalone Aloe Vera Alphadolone A Sheet1 A Abamectin Acetazolamide sodium Adenosine-5-monophosphate Aklomide Albendazole Alfaxalone Aloe vera Alphadolone Acetate Alpha-galactosidase Altrenogest Amikacin and its salts Aminopentamide Aminopyridine Amitraz Amoxicillin Amphomycin Amphotericin B Ampicillin Amprolium Anethole Apramycin Asiaticoside Atipamezole Avoparcin Azaperone B Bambermycin Bemegride Benazepril Benzathine cloxacillin Benzoyl Peroxide Benzydamine Bephenium Bephenium Hydroxynaphthoate Betamethasone Boldenone undecylenate Boswellin Bromelain Bromhexine 2-Bromo-2-nitropan-1, 3 diol Bunamidine Buquinolate Butamisole Butonate Butorphanol Page 1 Sheet1 C Calcium glucoheptonate (calcium glucoheptogluconate) Calcium levulinate Cambendazole Caprylic/Capric Acid Monoesters Carbadox Carbomycin Carfentanil Carnidazole Carnitine Carprofen Cefadroxil Ceftiofur sodium Centella asiatica Cephaloridine Cephapirin Chlorine dioxide Chlormadinone acetate Chlorophene Chlorothiazide Chlorpromazine HCl Choline Salicylate Chondroitin sulfate Clazuril Clenbuterol Clindamycin Clomipramine Clopidol Cloprostenol Clotrimazole Cloxacillin Colistin sulfate Copper calcium edetate Copper glycinate Coumaphos Cromolyn sodium Crystalline Hydroxycobalamin Cyclizine Cyclosporin A Cyprenorphine HCl Cythioate D Decoquinate Demeclocycline (Demethylchlortetracycline) Page 2 Sheet1 Deslorelin Desoxycorticosterone Pivalate Detomidine Diaveridine Dichlorvos Diclazuril Dicloxacillin Didecyl dimethyl ammonium chloride Diethanolamine Diethylcarbamazine Dihydrochlorothiazide Diidohydroxyquin Dimethylglycine Dimethylphthalate Dimethyl Sulfoxide Dimetridazole Diminazene Aceturate Dinitolmide (3,5-Dinitro-o-toluamide) (Zoalene) Dinoprost Dioctyl dimethyl ammonium chloride Dipenidam Diprenorphine Diprophylline Disophenol Dithiazanine iodide Diuredosan Doramectin Doxapram Doxepin Doxycycline Dyclonine E Emamectin Enalapril Enflurane Enilconazole Enrofloxacin Enterococcus faecium culture Eprinomectin Eprofloxacin Epsiprantel Erythromycin (hydrochloride, thyocyanate, stearate) Estrone Page 3 Sheet1 Etamiphylline Etorphine F Famphur Febantel Fenbendazole Fenprostalene Fenthion Fentichlor Fertirelin Florfenicol Flumethasone Flunixin meglumine Fluocinolone Fluocinonide Fluoroprednisolone Fluprostenol Flurogestone Flutamide Formosulfathiazole Framycetin Furadantin Furaltadone Furazolium chloride Furosemide Fusidic acid G Gentamicin Gleptoferron Glucosamine Glycarbylamide (1H-imidazole-4,5- dicarboxamide) Glycarsamide Glyceryl guaicolate Gonadorelin Griseofulvin H Halofuginone Halothane Haloxon Hamamelis (witch hazel extract) Heptaminol Hetacillin Homidium Page 4 Sheet1 Hyaluronic acid Hydriodic acid Hydrochlorothiazide Hydrocotyle (Centella) Hydroxymethylprogesterone acetate Hydroxyprogesterone acetate Hydroxyzine Hygromycin 4-5 Imidazole dicarboxamide (1H-imidazole- 4,5-dicarboxamide) I Inosine Insulin Iodochlorhydroxyquin Iodoquinol (Diiodohydroxyquin) Ipronidazole hydrochloride Isoflupredone Isoflurane Isoxuprine Ivermectin K Kanamycin Ketamine Ketoconazole Ketoprofen L Lasalocid Lauricidin (Glycerol Monolaurate) Levamisole Levothyroxine sodium d-Limonene (orange peel oil) Lincomycin Linear Dodecyl Benzene Sulfonic Acid Liothyronine Loxapine Lufenuron Luprostiol M Maduramicin Mannitol Mazipredone Mebendazole Meclofenamic Acid Page 5 Sheet1 Medroxyprogesterone Megestrol Melatonin Melengestrol Meloxicam Mepivacaine Meprobamate 2-Mercaptobenzothiazole Metallibure Methacide Methandriol (Methylandrostenediol) Methanol Methocarbamol Methoserpate Methoxyflurane Methylsulfonylmethane Methylpyriline Metomidate Metrifonate Metronidazole Mibolerone Miconazole nitrate Milbemycin Monensin Moxidectin N Nafcillin Naladixic acid Naloxone Nandrolone Naphthalophos Narasin Neguvon Nequinate Nicarbazin Niclosamide Nifuraldezone Nifurpirinol Nifursol Nithiazide Nitroscanate Norethandrolone Noscapine Nosiheptide Novobiocin Page 6 Sheet1 O Octyl decyl dimethyl ammonium chloride Octyl Dimethyl para amino benzoic acid Octyl thiobenzoate Oleandomycin Orange peel oil (d-limonene) Orbifloxacin Orgotein Ormetoprim Oxantel Oxfendazole Oxibendazole Oxygen (medical gas) P Paraformaldehyde Pentachlorophenol Pentapiperidine Pentazocine lactate Pentoxifylline Phencyclidine Pilocarpine Piperacetazine Piretanide Pirlimycin Poloxalene Poly (Iminoimidocarbonyliminoimidocarbonylimino hescamethylene) Hydrochloride Polymyxin methane sulfonate Polysulfate Glycosaminoglycan Potassium bromide Praziquantel Prednisolone Tebutate Prednisolone Trimethyl Acetate Pregelatinized Starch Primidone Propiomazine HCl Propionylpromazine Propiopromazine Propofol Propolis Prostalene Pyrantel Pyrimethamine Page 7 Sheet1 Q Quinine Hydrochloride Quinine Sulfate R Robenidine Rolitetracyline Romifidine Ronidazole Ronnel Ruelene S Salinomycin Sodium Selegiline Semduramicin Shark Cartilage Sodium Acetazolamide Sodium alkylate sulfonate Sodium ceftiofur Sodium cephapirin Sodium Clavulate Sodium cloxacillin Sodium Cromoglycate Sodium Cromolyn Sodium dicloxacillin monohydrate Sodium dodecyl benzene sulfonate iodine complex Sodium Hyaluronate Sodium Lasalocid Sodium levothyroxine Sodium liothyronine Sodium novobiocin Sodium oleate Sodium pentosan polysulphate Sodium salinomycin Sodium selenite Sodium sulfabromomethazine Sodium sulfachloropyrazine monohydrate Sodium sulfaethoxypyridazine Sodium sulfobromomethazine Sodium thiosalicylate Spectinomycin Spiramycin Sputolysin Squalene Stanozolol Page 8 Sheet1 Streptococcus thermophilus extract Styrylpyridinium Sulbactam Sulfachlorpyridazine Sulfadiazine Sulfadoxine Sulfaethoxypyridazine Sulfamethoxypyridazine 2-Sulfanilamidoquinoxaline T Teflubenzuron Testosterone cypionate Testosterone enanthate Tetrachlorvinphos 1,1,2-tetrafluorothane Tetramisole Thiabendazole Thymus Nucleic Acid Thyroactive casein Thyroglobulin Tiamulin Tilmicosin Tolazoline Tolfenamic acid Tolnaftate Trenbolone acetate Triamcinolone Tricaine Methanesulfonate Trichloracetic acid Trichlorfon Trichlormethiazide Trichlorophenyl (phenol?) Triclosan Trienbolone Trifluomeprazine Triiodothyronine Trimeprazine tartrate Trimethoprim Trimethylalkylammonium stearate Tromethamine Tripelennamine Tylosin V Vasopressine sp Vedaprofen Page 9 Sheet1 Virginiamycin W Witch hazel extract (Hamamelis extract) X Xylazine Y Yohimbine Z Zeranol Zoalene Page 10.
Load more

Recommended publications
  • (12) Patent Application Publication (10) Pub. No.: US 2008/0317805 A1 Mckay Et Al
    US 20080317805A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2008/0317805 A1 McKay et al. (43) Pub. Date: Dec. 25, 2008 (54) LOCALLY ADMINISTRATED LOW DOSES Publication Classification OF CORTICOSTEROIDS (51) Int. Cl. A6II 3/566 (2006.01) (76) Inventors: William F. McKay, Memphis, TN A6II 3/56 (2006.01) (US); John Myers Zanella, A6IR 9/00 (2006.01) Cordova, TN (US); Christopher M. A6IP 25/04 (2006.01) Hobot, Tonka Bay, MN (US) (52) U.S. Cl. .......... 424/422:514/169; 514/179; 514/180 (57) ABSTRACT Correspondence Address: This invention provides for using a locally delivered low dose Medtronic Spinal and Biologics of a corticosteroid to treat pain caused by any inflammatory Attn: Noreen Johnson - IP Legal Department disease including sciatica, herniated disc, Stenosis, mylopa 2600 Sofamor Danek Drive thy, low back pain, facet pain, osteoarthritis, rheumatoid Memphis, TN38132 (US) arthritis, osteolysis, tendonitis, carpal tunnel syndrome, or tarsal tunnel syndrome. More specifically, a locally delivered low dose of a corticosteroid can be released into the epidural (21) Appl. No.: 11/765,040 space, perineural space, or the foramenal space at or near the site of a patient's pain by a drug pump or a biodegradable drug (22) Filed: Jun. 19, 2007 depot. E Day 7 8 Day 14 El Day 21 3OO 2OO OO OO Control Dexamethasone DexamethasOne Dexamethasone Fuocinolone Fluocinolone Fuocinolone 2.0 ng/hr 1Ong/hr 50 ng/hr 0.0032ng/hr 0.016 ng/hr 0.08 ng/hr Patent Application Publication Dec. 25, 2008 Sheet 1 of 2 US 2008/0317805 A1 900 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 80.0 - 7OO – 6OO - 5OO - E Day 7 EDay 14 40.0 - : El Day 21 2OO - OO = OO – Dexamethasone Dexamethasone Dexamethasone Fuocinolone Fluocinolone Fuocinolone 2.0 ng/hr 1Ong/hr 50 ng/hr O.OO32ng/hr O.016 ng/hr 0.08 nghr Patent Application Publication Dec.
    [Show full text]
  • Full Text in Pdf Format
    DISEASES OF AQUATIC ORGANISMS Published July 30 Dis Aquat Org Oral pharmacological treatments for parasitic diseases of rainbow trout Oncorhynchus mykiss. 11: Gyrodactylus sp. J. L. Tojo*, M. T. Santamarina Department of Microbiology and Parasitology, Laboratory of Parasitology, Faculty of Pharmacy, Universidad de Santiago de Compostela, E-15706 Santiago de Compostela, Spain ABSTRACT: A total of 24 drugs were evaluated as regards their efficacy for oral treatment of gyro- dactylosis in rainbow trout Oncorhj~nchusmykiss. In preliminary trials, all drugs were supplied to infected fish at 40 g per kg of feed for 10 d. Twenty-two of the drugs tested (aminosidine, amprolium, benznidazole, b~thionol,chloroquine, diethylcarbamazine, flubendazole, levamisole, mebendazole, n~etronidazole,mclosamide, nitroxynil, oxibendazole, parbendazole, piperazine, praziquantel, roni- dazole, secnidazole, tetramisole, thiophanate, toltrazuril and trichlorfon) were ineffective Triclabenda- zole and nitroscanate completely eliminated the infection. Triclabendazole was effective only at the screening dosage (40 g per kg of feed for 10 d), while nitroscanate was effective at dosages as low as 0.6 g per kg of feed for 1 d. KEY WORDS: Gyrodactylosis . Rainbow trout Treatment. Drugs INTRODUCTION to the hooks of the opisthohaptor or to ulceration as a result of feeding by the parasite. The latter is the most The monogenean genus Gyrodactylus is widespread, serious. though some individual species have a restricted distri- Transmission takes place largely as a result of direct bution. Gyrodactyloses affect numerous freshwater contact between live fishes, though other pathways species including salmonids, cyprinids and ornamen- (contact between a live fish and a dead fish, or with tal fishes, as well as marine fishes including gadids, free-living parasites present in the substrate, or with pleuronectids and gobiids.
    [Show full text]
  • Comparative Efficacies of Commercially Available Benzimidazoles Against Pseudodactylogyrus Infestations in Eels
    DISEASES OF AQUATIC ORGANISMS Published October 4 Dis. aquat. Org. l Comparative efficacies of commercially available benzimidazoles against Pseudodactylogyrus infestations in eels ' Department of Fish Diseases, Royal Veterinary and Agricultural University, 13 Biilowsvej, DK-1870 Frederiksberg C, Denmark Department of Pharmacy, Royal Veterinary and Agricultural University, 13 Biilowsvej. DK-1870 Frederiksberg C,Denmark ABSTRACT: The antiparasitic efficacies of 9 benzimidazoles in commercially avalable formulations were tested (water bath treatments) on small pigmented eels Anguilla anguilla, expenmentally infected by 30 to 140 specimens of Pseudodactylogyrus spp. (Monogenea).Exposure time was 24 h and eels were examined 4 to 5 d post treatment. Mebendazole (Vermox; 1 mg 1-') eradicated all parasites, whereas luxabendazole (pure substance) and albendazole (Valbazen) were 100 % effective only at a concen- tration of 10 mg I-'. Flubendazole (Flubenol), fenbendazole (Panacur) and oxibendazole (Lodltac) (10 mg l-') caused a reduction of the infection level to a larger extent than did triclabendazole (Fasinex) and parbendazole (Helmatac).Thiabendazole (Equizole), even at a concentration as high as 100 mg l-', was without effect on Pseudodactylogyrus spp. INTRODUCTION range of commercially available benzimidazole com- pounds. If drug resistance will develop under practical The broad spectrum anthelmintic drug mebendazoIe eel-farm conditions in the future, it is likely to be was reported as an efficacious compound against infes- recognized during treatments with commercially avail- tations of the European eel Anguilla anguilla with gill able drug formulations. Therefore this type of drug parasitic monogeneans of the genus Pseudodactylo- preparations were used in the present study. gyms (Szekely & Molnar 1987, Buchmann & Bjerre- gaard 1989, 1990, Mellergaard 1989).
    [Show full text]
  • Bulletin Leading the Fight Against Heartworm Disease
    BULLETIN LEADING THE FIGHT AGAINST HEARTWORM DISEASE SEPTEMBER HEARTWORM 2017 Q&A VOLUME 44 No. 3 Heartworm History: In What Year Was Heartworm First INSIDE THIS ISSUE Treated? Page 4 From the President Page 8 Research Update Abstracts from the Literature Page 14 Heartworm Hotline: Role of Heat Treatment in Diagnostics Page 19 NEW! Best Practices: Minimizing Heartworm Transmission in Relocated Dogs uestions from members, prac- published in the 1998 AHS Symposium 1 titioners, technicians, and the Proceedings. Dr. Roncalli wrote, “The Page 21 Qgeneral public are often submit- first trial to assess the efficacy of a Welcome Our New AHS ted to the American Heartworm Society microfilaricide (natrium antimonyl tar- Student Liaisons (AHS) via our website. Two of our AHS trate) was conducted some 70 years Board members, Dr. John W.McCall and ago (1927) in Japan by S. Itagaki and R. Page 25 Dr. Tom Nelson, provided the resources Makino.2 Fuadin (stibophen), a trivalent In the News: Surgeons to answer this question: In What Year antimony compound, was tested, intra- Remove a Heartworm from Was Heartworm First Treated? venously, as a microfilaricide by Popescu the Femoral Artery of a Cat The first efforts to treat canine heart- in 1933 in Romania and by W.H. Wright worm disease date back to the 1920s. Dr. and P.C. Underwood in 1934 in the USA. Page 26 Nelson referenced a review article by Dr. In 1949, I.C. Mark evaluated its use Quarterly Update Raffaele Roncalli, “Tracing the History of intraperitoneally.” What’s New From AHS? Heartworms: A 400 Year Perspective,” Continues on page 7 American Heartworm Society / PO Box 8266, Wilmington, DE 19803-8266 Become an American Heartworm Society www.heartwormsociety.org / [email protected] fan on Facebook! Follow us on Twitter! OUR GENEROUS SPONSORS PLATINUM LEVEL PO Box 8266 Wilmington, DE 19803-8266 [email protected] www.heartwormsociety.org Mission Statement The mission of the American Heartworm Society is to lead the vet- erinary profession and the public in the understanding of heartworm disease.
    [Show full text]
  • CAUTION Or Streams with the Product Or Used Containers
    PROTECTION OF WILDLIFE, FISH, CRUSTACEANS AND THE ENVIRONMENT Abamectin is extremely toxic to aquatic species. DO NOT contaminate dams, rivers CAUTION or streams with the product or used containers. KEEP OUT OF REACH OF CHILDREN FIRST AID READ SAFETY DIRECTIONS BEFORE OPENING OR USING If poisoning occurs contact a doctor or the Poisons Info Centre. Phone Australia FOR ANIMAL TREATMENT ONLY 13 11 26; New Zealand 0800 764 766. If skin contact occurs, remove contaminated clothing and wash skin thoroughly. ® SAFETY DIRECTIONS EQUITAK EXCEL ORAL PASTE HARMFUL IF SWALLOWED. May irritate the eyes and skin; avoid contact with eyes 3 in 1 Wormer for Horses and skin. Repeated exposure may cause allergic disorders. When opening the container and using the product, wear rubber gloves. Wash hands after use. DESCRIPTION EMERGENCY RESPONSE A pale cream to tan coloured, apple flavoured, palatable paste with a characteristic In case of spillage wear appropriate protective clothing and prevent material from odour and taste. Each gram contains Oxfendazole 200mg, Praziquantel 50mg and entering waterways. Absorb spills with inert material and place in waste containers. Abamectin 4mg. Wash the area with water and absorb with further inert material. Dispose of waste safely. MODE OF ACTION Abamectin stimulates the release of the neurotransmitter GABA in roundworms, MEAT WITHHOLDING PERIOD (HORSES): DO NOT USE less than 28 days which increases the membrane permeability of neurons to chloride ions. Normal before slaughter for human consumption. neural transmission is thus inhibited causing paralysis and death of the parasite. STORAGE Praziquantel affects the attachment of tapeworms to the host tissues by causing Store below 30°C (room temperature), tightly closed, in the original syringe and in spastic paralysis.
    [Show full text]
  • (12) Patent Application Publication (10) Pub. No.: US 2006/0110428A1 De Juan Et Al
    US 200601 10428A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2006/0110428A1 de Juan et al. (43) Pub. Date: May 25, 2006 (54) METHODS AND DEVICES FOR THE Publication Classification TREATMENT OF OCULAR CONDITIONS (51) Int. Cl. (76) Inventors: Eugene de Juan, LaCanada, CA (US); A6F 2/00 (2006.01) Signe E. Varner, Los Angeles, CA (52) U.S. Cl. .............................................................. 424/427 (US); Laurie R. Lawin, New Brighton, MN (US) (57) ABSTRACT Correspondence Address: Featured is a method for instilling one or more bioactive SCOTT PRIBNOW agents into ocular tissue within an eye of a patient for the Kagan Binder, PLLC treatment of an ocular condition, the method comprising Suite 200 concurrently using at least two of the following bioactive 221 Main Street North agent delivery methods (A)-(C): Stillwater, MN 55082 (US) (A) implanting a Sustained release delivery device com (21) Appl. No.: 11/175,850 prising one or more bioactive agents in a posterior region of the eye so that it delivers the one or more (22) Filed: Jul. 5, 2005 bioactive agents into the vitreous humor of the eye; (B) instilling (e.g., injecting or implanting) one or more Related U.S. Application Data bioactive agents Subretinally; and (60) Provisional application No. 60/585,236, filed on Jul. (C) instilling (e.g., injecting or delivering by ocular ion 2, 2004. Provisional application No. 60/669,701, filed tophoresis) one or more bioactive agents into the Vit on Apr. 8, 2005. reous humor of the eye. Patent Application Publication May 25, 2006 Sheet 1 of 22 US 2006/0110428A1 R 2 2 C.6 Fig.
    [Show full text]
  • Restricted Use Chemicals by Product Name 09/14/2016
    Plant Health - Pesticide and Fertilizer Section 8995 E. Main St. , Reynoldsburg, Ohio 43068 Phone: Phone (614) 728-6396Fax: Fax (614) 728-4221 Governor: John R. Kasich Lt. Governor: Mary Taylor www.agri.ohio.gov [email protected] Director: David T. Daniels Page 1 of 33 Restricted Use Chemicals by Product Name 09/14/2016 Registered Thru: 6/30/2017 12:00:00 AM Product_name Active_Ingredients Company_Name EPA_Number Private Commercial AATREX 4L HERBICIDE INC Atrazine (ANSI) SYNGENTA CROP 100-497 1, 3, 4, 7 2C, 4A, 6A PROTECTION LLC AATREX NINE-O HERBICIDE INC Atrazine (ANSI) SYNGENTA CROP 100-585 1, 3, 4, 7 2C, 4A, 5, 6A, 8 PROTECTION LLC ABACUS AGRICULTURAL MITICIDE/ INSECTICIDE Abamectin ROTAM NORTH 83100-4-83979 3 1, 2A, 2B AMERICA INC ABACUS V Abamectin ROTAM NORTH 83100-32-83979 3 1, 2B, 2C AMERICA INC ABAMECTIN 0.15EC SELECT Abamectin PRIME SOURCE, LLC 89442-20 None None ABAMEX MITICIDE-INSECTICIDE Abamectin (ANSI) NUFARM AMERICAS 228-734 3 2A, 2B INC 228 ABBA 0.15 MAKHTESHIM-AGAN OF 66222-191 None None NORTH AMER INC ABBA 0.15 EC MITICIDE INSECTICIDE Abamectin MAKHTESHIM-AGAN OF 66222-139 3 1, 2A NORTH AMER INC ABBA ULTRA MITICIDE INSECTICIDE Abamectin (ANSI) MAKHTESHIM-AGAN OF 66222-226 3 2B NORTH AMER INC ACELLUS AZT Acetochlor; Atrazine GROWMARK INC 62719-671-534 1, 2 2C ACELLUS AZT LITE Acetochlor; Atrazine GROWMARK INC 62719-670-534 1, 2 2C ACETO BIFENTHRIN 2 EC Bifenthrin ACETO AGRICULTURAL 2749-556 1, 3 2A, 2B CHEMICALS CORP ACURON HERBICIDE Atrazine; S-metolachlor; Mesotrione; SYNGENTA CROP 100-1466 1, 2 2C Bicyclopyrone
    [Show full text]
  • Computational Studies of Drug Repurposing Targeting P-Glycoprotein Mediated Multidrug-Resistance Phenotypes in Agents of Neglect
    bioRxiv preprint doi: https://doi.org/10.1101/2020.06.12.147926; this version posted June 12, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY 4.0 International license. Computational studies of drug repurposing targeting P- glycoprotein mediated multidrug-resistance phenotypes in agents of neglected tropical diseases Nivedita Jaishankar 1, Sangeetha Muthamilselvan 2, Ashok Palaniappan 1,2* 1 Department of Biotechnology, Sri Venkateswara College of Engineering, Post Bag No. 1, Pennalur, Sriperumbudur Tk 602117. India 2 Department of Bioinformatics, School of Chemical and BioTechnology, SASTRA Deemed University, Thanjavur 613401. India * Corresponding author: [email protected] ABSTRACT Mammalian ABCB1 P-glycoprotein is an ATP- dependent efflux pump with broad substrate specificity associated with cellular drug resistance. Homologous to this role in mammalian biology, the P-glycoprotein of agents of neglected tropical diseases (NTDs) mediates the emergence of multidrug- resistance phenotypes. The clinical and socioeconomic implications of NTDs are exacerbated by the lack of research interest among Big Pharma for treating such conditions. This work aims to characterise P-gp homologues in certain agents of key NTDs, namely (1) Protozoa: Leishmania major, Trypanosoma cruzi; (2) Helminths: Onchocerca volvulus, Schistosoma mansoni. PSI-BLAST searches against the genome of each of these organisms confirmed the presence of P-gp homologues. Each homologue was aligned against five P- gp sequences of known structure, to identify the most suitable template based on sequence homology, phylogenetic nearest neighbor, and query coverage.
    [Show full text]
  • Chemotherapy of Gastrointestinal Helminths
    Chemotherapy of Gastrointestinal Helminths Contributors J. H. Arundel • J. H. Boersema • C. F. A. Bruyning • J. H. Cross A. Davis • A. De Muynck • P. G. Janssens • W. S. Kammerer IF. Michel • M.H. Mirck • M.D. Rickard F. Rochette M. M. H. Sewell • H. Vanden Bossche Editors H. Vanden Bossche • D.Thienpont • P.G. Janssens UNIVERSITATS- BlfiUOTHElC Springer-Verlag Berlin Heidelberg New York Tokyo Contents CHAPTER 1 Introduction. A. DAVIS A. Pathogenic Mechanisms in Man 1 B. Modes of Transmission 2 C. Clinical Sequelae of Infection 3 D. Epidemiological Considerations 3 E. Chemotherapy 4 F. Conclusion 5 References 5 CHAPTER 2 Epidemiology of Gastrointestinal Helminths in Human Populations C. F. A. BRUYNING A. Introduction 7 B. Epidemiological or "Mathematical" Models and Control 8 C. Nematodes 11 I. Angiostrongylus costaricensis 11 II. Anisakis marina 12 III. Ascaris lumbricoides 14 IV. Capillaria philippinensis 21 V. Enterobius vermicularis 23 VI. Gnathostoma spinigerum 25 VII. Hookworms: Ancylostoma duodenale and Necator americanus . 26 VIII. Oesophagostoma spp 32 IX. Strongyloides stercoralis 33 X. Ternidens deminutus 34 XI. Trichinella spiralis 35 XII. Trichostrongylus spp 38 XIII. Trichuris trichiura 39 D. Trematodes 41 I. Echinostoma spp 41 II. Fasciolopsis buski 42 III. Gastrodiscoides hominis 44 IV. Heterophyes heterophyes 44 V. Metagonimus yokogawai 46 X Contents E. Cestodes 47 I. Diphyllobothrium latum 47 II. Dipylidium caninum 50 III. Hymenolepis diminuta 51 IV. Hymenolepis nana 52 V. Taenia saginata 54 VI. Taenia solium 57 VII. Cysticercosis cellulosae 58 References 60 CHAPTER 3 Epidemiology and Control of Gastrointestinal Helminths in Domestic Animals J. F. MICHEL. With 20 Figures A. Introduction 67 I.
    [Show full text]
  • Veterinary Guide to Resistance & Parasites
    Veterinary Guide to Resistance & Parasites How to make the Get Rotation Right deworming strategy part of your equine health wellness protocol. ||||||||||||||||||||||||||||||||||||||||| GET ROTATION RIGHT Resistant parasites – veterinary involvement is needed now. Deworming has come a long way in the past 50 years – from products that were nearly toxic and required complicated tubing to the easy-to-administer dewormers we know now. As more horse owners recognize the value of regular deworming, past troublemakers such as large strongyles have become much less of a threat. Still, deworming is nothing to take lightly. As internal parasites become more resistant, your expertise is needed Horseowners unknowingly more than ever to make sure deworming programs remain efficient contribute to resistance. and effective. Only with veterinary involvement will we control parasite • Rotating brand names, not populations, combat resistance and get rotation right. chemical classes – general confusion about when and RESISTANCE IS REAL: MULTIPLE DRUGS, MULTIPLE PARASITES. how to use different classes • No new drug class since avermectins in 1981. of dewormers. • Benzimidazole resistance in cyathostomes.1-3 • Lack of knowledge about • Pyrantel resistance in cyathostomes and ascarids.4-8,11 resistance issues. • Ivermectin and moxidectin resistance among ascarids.8,9,11 • Deworming many horses more • Early warning signs of macrocyclic-lactone-resistant cyathostomes.10 frequently than necessary. • Health-related issues caused by parasites: • Misunderstanding about the ~ Ascarids (roundworms) unique properties of larvicidal Verminous pneumonia: cough, nasal discharge, low-grade fever treatments and how to maximize Unthriftiness – rough hair coat their efficacy. Intestinal obstruction/colic • Underdosing their horses. Intestinal perforation leading to peracute death Decreased performance and reduced weight gain ~ Cyathostomes (small strongyles) Most common in young and old horses, but can afflict any horse.
    [Show full text]
  • )&F1y3x PHARMACEUTICAL APPENDIX to THE
    )&f1y3X PHARMACEUTICAL APPENDIX TO THE HARMONIZED TARIFF SCHEDULE )&f1y3X PHARMACEUTICAL APPENDIX TO THE TARIFF SCHEDULE 3 Table 1. This table enumerates products described by International Non-proprietary Names (INN) which shall be entered free of duty under general note 13 to the tariff schedule. The Chemical Abstracts Service (CAS) registry numbers also set forth in this table are included to assist in the identification of the products concerned. For purposes of the tariff schedule, any references to a product enumerated in this table includes such product by whatever name known. Product CAS No. Product CAS No. ABAMECTIN 65195-55-3 ACTODIGIN 36983-69-4 ABANOQUIL 90402-40-7 ADAFENOXATE 82168-26-1 ABCIXIMAB 143653-53-6 ADAMEXINE 54785-02-3 ABECARNIL 111841-85-1 ADAPALENE 106685-40-9 ABITESARTAN 137882-98-5 ADAPROLOL 101479-70-3 ABLUKAST 96566-25-5 ADATANSERIN 127266-56-2 ABUNIDAZOLE 91017-58-2 ADEFOVIR 106941-25-7 ACADESINE 2627-69-2 ADELMIDROL 1675-66-7 ACAMPROSATE 77337-76-9 ADEMETIONINE 17176-17-9 ACAPRAZINE 55485-20-6 ADENOSINE PHOSPHATE 61-19-8 ACARBOSE 56180-94-0 ADIBENDAN 100510-33-6 ACEBROCHOL 514-50-1 ADICILLIN 525-94-0 ACEBURIC ACID 26976-72-7 ADIMOLOL 78459-19-5 ACEBUTOLOL 37517-30-9 ADINAZOLAM 37115-32-5 ACECAINIDE 32795-44-1 ADIPHENINE 64-95-9 ACECARBROMAL 77-66-7 ADIPIODONE 606-17-7 ACECLIDINE 827-61-2 ADITEREN 56066-19-4 ACECLOFENAC 89796-99-6 ADITOPRIM 56066-63-8 ACEDAPSONE 77-46-3 ADOSOPINE 88124-26-9 ACEDIASULFONE SODIUM 127-60-6 ADOZELESIN 110314-48-2 ACEDOBEN 556-08-1 ADRAFINIL 63547-13-7 ACEFLURANOL 80595-73-9 ADRENALONE
    [Show full text]
  • An Evaluation of Eprinomectin Extended-Release Injectable (Longrange®) on the Performance of Yearling Cattle on Pasture in Western Canada
    PEER REVIEWED © Copyright American Association American© Copyright ofBovine Practitioners; open access distribution. An evaluation of eprinomectin extended-release injectable (LongRange®) on the performance of yearling cattle on pasture in western Canada Ryan D. Rademacher, BSc, DVM; Eric J. Behlke, BSc, MSc, PhD, DVM; Sandi L. Parr, BSc, MSc, PhD; Sherry J. Hannon, DVM, MVetSc, PhD; Christina M. Williams, BSc, MSc; R. Kent Fenton, DVM; G. Kee Jim, DVM; Calvin W. Booker, DVM, MVetSc Feedlot Health Management Services Ltd., PO Box 140, Okotoks, Alberta, Canada T1S 2A2 Corresponding author: Dr. Calvin Booker; Tel: (403) 938-5151; Fax: (403) 938-5175; [email protected] Abstract sous forme injectable a la dose de 0.45 mg/lb (1.0 mg/kg) d'unite de poids corporel (PC) dans la partie lache de la peau During the pre-shipment handling procedures at each devant l'epaule. Les animaux dans le groupe IVER (1524 ani­ of 2 feedlots of origin, mixed-breed beef steers were weighed, maux) ont re<;u a l'allocation une application d'ivermectine sur stratified into weight blocks, and simultaneously randomized le long de la ligne superieure du garrot jusqu’a l’attache de la within weight block to 1 of 2 experimental groups (LONG or queue a la dose de 0.23 mg/lb (0.5 mg/kg) d’unite de PC. Apres IVER) prior to shipment to pasture. Animals in the LONG l’allocation, les animaux des deux groupes experimentaux ont group (1523 animals) received a subcutaneous injection of ete amalgames a l'interieur de chaque bloc de poids et selon le eprinomectin extended-release injectable at a dosage of 0.45 pare d'alimentation d’origine et sont restes dans ces groupes mg/lb (1.0 mg/kg) body weight (BW) in the loose skin in front amalgames pendant toute la duree de l’etude.
    [Show full text]