DOCSLIB.ORG

The Call of Coronal Duty

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
The Call of Coronal Duty MARCH 2021 # 95 Upfront In My View Feature Sitting Down With Solar cycles and old mold Starting conversations about Is there life on Mars? Biologics Explorer, ethics in clinical proteomics Davy Guillarme 07 12 28 – 33 50 – 51 The Call of Coronal Duty How proteomics became a crucial weapon in the fight against COVID-19 16 – 26 www.theanalyticalscientist.com Load. Load. Ready. Ready. Go! Go! Enhanced Features of the Vi-CELL BLU BLU Vi-CELL the of Features Enhanced Cell Viability Analyzer include: include: Analyzer Viability Cell - Expanded capacity (24-position carousel or a 96-well plate) plate) 96-well a or carousel (24-position capacity Expanded - - Small sample volume volume sample Small - - Walk-away operation with on-the-fly sample login login sample on-the-fly with operation Walk-away - - 50% faster than the Vi-CELL XR in FAST Mode Mode FAST in XR Vi-CELL the than faster 50% - - Small laboratory footprint footprint laboratory Small - - User-friendly reagent system system reagent User-friendly - - Life-cycle service and support support and service Life-cycle - LEARN MORE about the Vi-CELL BLU Cell Viability Viability Cell BLU Vi-CELL the about MORE LEARN Analyzer at www.beckman.com/blu www.beckman.com/blu at Analyzer © 2021 Beckman Coulter, Inc. All rights reserved. Beckman Coulter, the stylized logo and the Beckman Coulter product and service ce rvi e s d n a t c odu r p Coulter Beckman the and logo ed z tyli s the ter, ul Co n a ckm Be ed. erv es r ts h rig All . c In , Coulter n a eckm B 1 202 © names mentioned herein are trademarks or registered trademarks of Beckman Coulter, Inc. in the United States and other countries. countries. r e oth d n a s State ed nit U e h t in nc. I , Coulter n a ckm e B f o ademarks r t ed ster egi r r o ademarks r t e ar ein her ed on ti n me s me na beckman.com n.com beckma Always Look on the Bright Side of Life Editorial A mantra to live by in the age of COVID-19 ocusing on the positives is often easier said than done – especially during a pandemic. But I wanted to use this editorial as an opportunity to encourage Fus all (myself included) to do so. A prime example: most people will recognize the immortalized lyrics from the legendary Monty Python in the title. The same song was played at my grandad’s funeral. Does it upset me? A little. But it also fills me with hope. As my grandad would have wanted, it forces me to reflect on the joy we shared with one another – and the joy of life itself. It’s been a long year. Much of the world entered lockdown or other restrictions in early 2020. Some of us have lost loved ones. Many have suffered in other ways. All of us are missing friends and family. But there are reasons to be positive. The first: vaccines have landed! Designing these miracles of medicine in response to a threat has never happened so quickly – that’s a reason to smile! And, here in the UK, we are already seeing hospitalizations drop (another frown deterrent!). Accordingly, this issue celebrates pharmaceutical feats, from the first instance of subcellular drug quantitation (see page 34) to Davy Guillarme’s own forays in the field (on page 51). Reason two: movement towards equity in science and beyond. In our field, coalitions have formed to support groups traditionally disadvantaged in the sciences. The Coalition of Black Mass Spectrometrists is a great example – as is the Females in Mass Spectrometry community. Groups like these are a driving force for positive change and equity – something we can all smile about! They also champion a message aligned with the theme of this year’s International Women’s Day theme: “Choose to Challenge.” We’re marking the occasion (and the wider Women’s History Month) by shouting about the historical successes of women in analytical chemistry (see pages 6 and 7) and the need for female representation and role models (page 12). And a third reason? Normality is returning! The “new normal” will soon be the “no thank you,” and we will be able to celebrate with the people we love most. If my grandad’s passing taught me anything, it’s how important those moments are. Until then, I hope our publication can at least put a smile on your face. And remember: always look on the bright side of life (da- dum, da-da da-da da-dum)! Matthew Hallam Editor www.theanalyticalscientist.com Contents 28 07 16 In My View 10 Work-integrated learning is a key tool for improving the employability of graduates, 03 Editorial Upfront Bhavik Patel and Fiona Always Look on the Bright Side Ponikwer argue of Life, by Matthew Hallam 06 Recent research hits, including – but not limited to – LC-MS 12 Isabelle Kohler discusses the analysis of antibiotics in food need for female representation On The Cover and a combined spectroscopy and role models in analytical approach to glioblastoma chemistry Research in progress: Karel diagnosis Bezstarosti, a key contributor 14 Sebastian Porsdam Mann, to the SARS-CoV-2 work Philipp Geyer, Peter Treit, and described in our cover feature, Matthias Mann are here to drives the mass spectrometer kickstart important conversations about ethics in clinical proteomics ISSUE 95 - MARCH 2021 28 Feel free to contact any one of us: [email protected] Content Team Editor - Matthew Hallam Charlotte Barker (Associate Content Director) Lauren Robertson (Deputy Editor) Frank van Geel (Scientific Director) Commercial Team Publisher - Lee Noyes Gaurav Avasthi (Business Development Manager) Nick Ransom (Business Development Executive Americas) Design Team Head of Design - Marc Bird Hannah Ennis (Senior Designer) 26 Charlotte Brittain (Designer) Digital Team Digital Team Lead - David Roberts Peter Bartley (Digital Producer Web/Email) Abygail Bradley (Digital Producer Web/App) Audience Team Audience Growth Strategy Manager – Brice Agamemnon CRM & Compliance 50 CRM & Compliance Manager - Tracey Nicholls Hayley Atiz (CRM Assistant) Commercial Support Team Internal Systems Manager - Jody Fryett Features Dan Marr (Campaign Reporting Analyst) Commercial Services Commercial Service and Social 16 The Call of Coronal Duty Media Manager - Matt Everett Jeroen Demmers, Perdita Kevin O'Donnell (Marketing Executive) Alice Daniels-Wright (Video Project Manager) Barran and Manfred Wuhrer Jess Lines (Project Support Coordinator) Lindsey Vickers (Sales Support Project Manager) walk us through the proteomics Jennifer Bradley (Sales Support Coordinator) battlegrounds in the fight Marketing Team against COVID-19 Marketing Manager - Katy Pearson Jo Baylay (Marketing Executive) Accounts Team 28 In Search of Sulfates Departments Kerri Benson (Accounts Assistant) – and Aliens! Emily Scragg (Accounts Apprentice) Juan Manuel Madriaga and 40 Solutions: From Big Pharma to Human Resources Duncan Stacey discuss their New Green Horizons: Lessons Human Resource Manager - Tara Higby Management Team contribution to sulfate analysis Learned with Ross Burns Chief Executive Officer - Andy Davies – a powerful tool in the hunt for Chief Operating Officer - Tracey Peers Senior Vice President (North America) - Fedra Pavlou signs of life on the Red Planet Financial Director - Phil Dale Commercial Director - Richard Hodson (and for protecting buildings Content Director - Rich Whitworth here on Earth!) Sitting Down With 34 Focusing on the Smaller Picture 50 Davy Guillarme, Senior Lecturer Change of address [email protected] Hayley Atiz, The Analytical Scientist, Texere Publishing Limited, Picking the brains of a and Research Associate, Booths Park 1, Chelford Road, Knutsford, Cheshire, WA16 8GS, UK mass spectrometrist and a School of Pharmaceutical General enquiries www.texerepublishing.com | [email protected] spectroscopist at the forefront of Sciences, University of Geneva, +44 (0) 1565 745 200 | [email protected] subcellular drug imaging Switzerland Distribution: TheAnalytical Scientist (ISSN 2051-4077), is published monthly by Texere Publishing Limited, Booths Park 1, Chelford Road, Knutsford, Cheshire, WA16 8GS, UK. Single copy sales $15 (plus postage, cost available on request [email protected]). Non-qualified annual subscription cost is available on request. Editorial California at Berkeley, USA Biosystems Research Peter Schoenmakers, Gary Hieftje, Indiana Institute, USA University of Amsterdam, Reprints & Permissions – [email protected] Advisory The copyright in the materials contained in this publication and the typographical University, USA (Retired) Luigi Mondello, University The Netherlands Board arrangement of this publication belongs to Texere Publishing Limited. No person may Hans-Gerd Janssen, of Messina, Italy Robert Kennedy, copy, modify, transmit, distribute, display, reproduce, publish, licence or create works from Chris Harrison, San Diego Unilever Research and Martin Gilar, Waters, USA University of Michigan, any part of this material or typographical arrangement, or otherwise use it, for any public State University, USA Development, The Michelle Reid, Cristal USA or commercial use without the prior written consent of Texere Publishing Limited. Christina Jones, Research Netherlands Therapeutics, The Ron Heeren, Maastricht The names, publication titles, logos, images and presentation style appearing in this chemist, NIST, USA Ian Wilson, Imperial Netherlands University, The publication which identify Texere Publishing Limited and/or its products and services, including but without limitation Texere and The Analytical Scientist are proprietary Emily Hilder, University of College London, UK Monika Dittmann, Netherlands South Australia, Australia marks of Texere Publishing Limited. Nothing contained in this publication shall be Jenny Van Eyk, Director Independent Analytical Samuel Kounaves, Tufts deemed to confer on any person any licence or right on the part of Texere Publishing Frantisec Svec, University of of the Advanced Clinical Scientist, Germany University, USA Limited with respect to any such name, title, logo, image or style. 6 Upfront Upfront Research Venusian Views Innovation Trends Six-wavelength spectroscopy unveils new details about the surface of Venus Beneath a thick, caustic atmosphere that is hot enough to melt lead lies the surface of our planetary neighbor.
Load more

Recommended publications
  • Lara (Lander Radioscience) on the Exomars 2020 Surface Platform
    EPSC Abstracts Vol. 13, EPSC-DPS2019-891-1, 2019 EPSC-DPS Joint Meeting 2019 c Author(s) 2019. CC Attribution 4.0 license. LaRa (Lander Radioscience) on the ExoMars 2020 Surface Platform. Véronique Dehant1,2, Sébastien Le Maistre1, Rose-Marie Baland1, Özgür Karatekin1, Marie-Julie Péters1, Attilio Rivoldini1, Tim Van Hoolst1, Bart Van Hove1, Marie Yseboodt1, and Alexander Kosov3 (1) Royal Observatory of Belgium (ROB), Brussels, Belgium, (2) Université catholique de Louvain, Louvain-la-Neuve, Belgium, (3) Space Research Institute Russian Academy of Sciences (IKI), Moscow, Russia Abstract The surface platform Kazachok will house the radio science experiment LaRa (Lander Radioscience) to support specific scientific objectives of the ExoMars 2020 mission. The LaRa experiment is described and the scientific objectives and strategies are detailed in this presentation. Figure 1. LaRa principle. 1. Introduction 2. The LaRa instrument In the last decade, several missions and observations As LaRa performs a coherent retransmission of the have brought new data on the planet Mars, obtained uplink carrier to the downlink carrier, the downlink by either spacecraft orbiting around Mars or landers frequency is scaled by a constant multiplier, the and rovers on the surface. Among other things, the transponder ratio (880/749). By emitting the uplink information acquired will improve our understanding signal from Earth, the masers in the ground stations of Mars’ interior, evolution and habitability. Data ensure frequency stability of LaRa’s radiosignal. obtained by new space missions are driving further The LaRa instrument is built in collaboration with progress in this field. In 2020, the European Space other Belgian actors under the lead of ESA PRODEX, Agency ESA and the Russian space agency and ROB providing the instrument specifications.
    [Show full text]
  • Matematikken Viser Vej Til Mars
    S •Matematikken The viser vej til Mars Kim Plauborg © The Terma Group 2016 THE BEGINNING Terma has been in Space since man walked on the Moon! © The Terma Group 2016 FROM ESRO TO EXOMARS Terma powered the first comet landing ever! BREAKING NEWS The mission ends today when the Rosetta satellite will set down on the surface In 2014 the Rosetta satellite deployed the small lander Philae, which landed on the cometof 67P morethe than 10 comet years after Rosetta was launched. © The Terma Group 2016 FROM ESRO TO EXOMARS Rosetta Mars Express Technology Venus Express evolution and Galileo enhancement Small GEO BepiColombo ExoMars © The Terma Group 2016 Why go Mars? Getting to and landing on Mars is difficult ! © The Terma Group 2016 THE EXOMARS PROGRAMME Two ESA missions to Mars in cooperation with Roscosmos with the main objective to search for evidence of life 2016 Mission Trace Gas Orbiter Schiaparelli 2020 Mission Rover Surface platform © The Terma Group 2016 EXOMARS 2016 14th March 2016 Launched from Baikonur cosmodrome, Kazakhstan © The Terma Group 2016 EXOMARS 2016 16th October 2016 Separation of Schiaparelli from the orbiter © The Terma Group 2016 SCHIAPARELLI Schiaparelli (EDM) - an entry, descent and landing demonstrator module © The Terma Group 2016 EXOMARS 2016 19th October 2016 Landing of Schiaparelli the surface of Mars © The Terma Group 2016 EXOMARS 2016 19th October 2016 Landing of Schiaparelli the surface of Mars © The Terma Group 2016 EXOMARS 2020 © The Terma Group 2016 TERMA AND EXOMARS Terma deliveries to the ExoMars 2016 mission • Remote Terminal Power Unit for Schiaparelli • Mission Control System • Spacecraft Simulator • Support for the Launch and Early Orbit Phase © The Terma Group 2016 ExoMars RTPU The RTPU is a central unit in the Schiaparelli lander.
    [Show full text]
  • Near-Infrared Chemical Imaging and the PAT Initiative NIR-CI Adds a Completely New Dimension to Conventional NIR Spectroscopy
    Molecular Spectroscopy Workbench Near-infrared Chemical Imaging and the PAT Initiative NIR-CI adds a completely new dimension to conventional NIR spectroscopy. E. Neil Lewis, Joe Schoppelrei, and Eunah Lee Dear and gentle readers, this month I present an important other manufacturing steps have on the final dosage form? To tool in the process analytical technologies (PAT) initiative: encourage the PAT initiative FDA is streamlining the mecha- Near-infrared chemical imaging (NIR-CI). You might wonder nism for adopting new technologies in pharmaceutical manu- why I am seemingly concentrating on IR and NIR. The an- facturing. swer is quite simple: I need all the heat I can get, here in New York. Seriously, E. Neil Lewis, Joe Schoppelrei, and The Role of Near-infrared Chemical Imaging (NIR-CI) Eunah Lee of Spectral Dimensions (Olney, MD) have put to- A typical tablet is not just a pressed block of a single material, gether an excellent explanation of what NIR-CI is and what but rather a complex matrix containing one or more active its part in PAT is and will be. For those of you who do not pharmaceutical ingredients (APIs), fillers, binders, disinte- know Neil Lewis, he is one of the pioneers in IR and NIR im- grants, lubricants, and other materials. A basic problem in aging. He has won numerous awards for his research at the pharmaceutical manufacturing is that a relatively simple for- National Institutes of Health (NIH) and subsequent accom- mulation with identical ingredients can produce widely vary- plishments. It is truly exciting to have this paper in my hum- ing therapeutic performance depending upon how the ingre- ble column and I know you will find it informative and enter- dients are distributed in the final matrix.
    [Show full text]
  • Comprehensive Bibliography on Martian Meteorites (Compiled by C
    Comprehensive Bibliography on Martian Meteorites (compiled by C. Meyer, March 2008) Abu Aghreb A.E., Ghadi A.M., Schlüter J., Schultz L. and Thiedig F. (2003) Hamadah al Hamra and Dar al Gani: A comparison of two meteorite fields in the Libyan Sahara (abs). Meteoritics & Planet. Sci. 38, A48. Agee Carl B. (2002) Garnet and majorite fractionation in the early Earth and Mars (abs#1862). Lunar Planet. Sci. XXXIII Lunar Planetary Institute, Houston. (CD-ROM). (see address of LPI in Appendix III) Agee C.B., Bogard Don D., Draper D.S., Jones J.H., Meyer Chuck and Mittlefehldt D.W. (2000) Proposed science requirements and acquisition priorities for the first Mars sample return (abs). In Concept and Approaches for Mars Exploration. Part 1 (ed. S. Hubbard) LPI Contribution # 1062. Lunar Planetary Institute, Houston. Agee C.B. and Draper Dave S. (2003) Melting of model Martian mantle at high pressure: Implications for the composition of the Martian basalt source region (abs#1408). Lunar Planet. Sci. Conf. 34th, Lunar Planetary Institute, Houston (CD-ROM). Agerkvist D.P. and Vistisen L. (1993) Mössbauer spectroscopy of the SNC meteorite Zagami (abs). Lunar Planet. Sci. XXIV, 1-2. Lunar Planetary Institute, Houston. Zagami Agerkvist D.P., Vistisen L., Madsen M.B. and Knudsen J.M. (1994) Magnetic properties of Zagami and Nakhla (abs). Lunar Planet. Sci. XXV, 1-2. Lunar Planetary Institute, Houston. Zagami Nakhla Akai J. (1997) Characteristics of iron-oxide and iron-sulfide grains in meteorites and terrestrial sediments, with special references to magnetite grains in Allan Hills 84001 (abs). Meteoritics & Planet. Sci.
    [Show full text]
  • How a Cartoon Series Helped the Public Care About Rosetta and Philae 13 How a Cartoon Series Helped the Public Care About Rosetta and Philae
    How a Cartoon Series Helped the Public Care about Best Practice Rosetta and Philae Claudia Mignone Anne-Mareike Homfeld Sebastian Marcu Vitrociset Belgium for European Space ATG Europe for European Space Design & Data GmbH Agency (ESA) Agency (ESA) [email protected] [email protected] [email protected] Carlo Palazzari Emily Baldwin Markus Bauer Design & Data GmbH EJR-Quartz for European Space Agency (ESA) European Space Agency (ESA) [email protected] [email protected] [email protected] Keywords Karen S. O’Flaherty Mark McCaughrean Outreach, space science, public engagement, EJR-Quartz for European Space Agency (ESA) European Space Agency (ESA) visual storytelling, fairy-tale, cartoon, animation, [email protected] [email protected] anthropomorphising Once upon a time... is a series of short cartoons1 that have been developed as part of the European Space Agency’s communication campaign to raise awareness about the Rosetta mission. The series features two anthropomorphic characters depicting the Rosetta orbiter and Philae lander, introducing the mission story, goals and milestones with a fairy- tale flair. This article explores the development of the cartoon series and the level of engagement it generated, as well as presenting various issues that were encountered using this approach. We also examine how different audiences responded to our decision to anthropomorphise the spacecraft. Introduction internet before the spacecraft came out of exciting highlights to come, using the fairy- hibernation (Bauer et al., 2016). The four tale narrative as a base. The hope was that In late 2013, the European Space Agency’s short videos were commissioned from the video would help to build a degree of (ESA) team of science communicators the cross-media company Design & Data human empathy between the public and devised a number of outreach activ- GmbH (D&D).
    [Show full text]
  • DLR Developments and Application Ideas for Interplanetary Cubesats
    DLR developments and application ideas for interplanetary cubesats iCubeSat, Milano 2019 Jens Biele1, Michael Maibaum1, Caroline Lange2, Thimo Grundmann2, Stephan Ulamec1, Marcus Thomas Knopp3, Frank-Cyrus Roshani3 1DLR German Aerospace Center, RB-MUSC, Cologne, Germany 2DLR German Aerospace Center, Bremen, Germany 3DLR German Aerospace Center, GSOC, Munich, Germany www.DLR.de • Chart 3 > Lecture > Author • Document > Date SKAD-Study [FRANK, MARCUS] • Orbiter as relais station for Mars-Rover • ………. Designs flown or studied (DLR) Hopper(10-25 kg) MASCOT (30, 70 kg) Philae (100 kg) Leonard MASCOT (10 kg) Folie 4 > Vortrag > Autor Folie 5 > Vortrag > Autor Study Flow of MASCOT („how to shrink a lander..“) • December 2008 – September 2009: feasibility study, with CNES, in context of Marco Polo and Hayabusa-2, with common requirements: • 3 iterations of different mass (95kg, 35kg & 10kg) and P/L • Settled on 10 kg lander package including 3 kg of P/L • Ho, T.-M., et al. (2016). "MASCOT—The Mobile Asteroid Surface Scout Onboard the Hayabusa2 Mission." Space Science Reviews 208(1-4): 339– 374. • ➔ Design of MASCOT 10 kg: a nanosat (30x30*20 cm³) . Could be a 18 U cubesat! Large ~ 95 kg, Philae hertitage Middle ~ 35 kg, Xtra Small ~ 10 kg, No post-landing Up-righting + mobility mobility MASCOT Payload (25% of total mass!) Instrument Science Goals Heritage Institute; PI/IM Mass [kg] MAG magnetization of the NEA MAG of ROMAP on Rosetta TU Braunschweig Lander (Philae), ESA VEX, 0,15 → formation history Themis K.H. Glassmeier / U. Auster mineralogical composition ESA ExoMars, Russia and characterize grains Phobos GRUNT, ESA size and structure of Rosetta, ESA ExoMars IAS Paris µOmega surface soil samples at μ- rover 2018, Rosetta / Philae J.P.
    [Show full text]
  • Army Acquisition Workforce Dependency on E-Mail for Formal
    ARMY ACQUISITION WORKFORCE DEPENDENCY ON E-MAIL FOR FORMAL WORK COORDINATION: FINDINGS AND OPPORTUNITIES FOR WORKFORCE PERFORMANCE IMPROVEMENT THROUGH E-MAIL-BASED SOCIAL NETWORK ANALYSIS KENNETH A. LORENTZEN May 2013 PUBLISHED BY THE DEFENSE ACQUISITION UNIVERSITY PRESS PROJECT ADVISOR: BOB SKERTIC CAPITAL AND NORTHEAST REGION, DAU THE SENIOR SERVICE COLLEGE FELLOWSHIP PROGRAM ABERDEEN PROVING GROUND, MD PAGE LEFT BLANK INTENTIONALLY .ARMY ACQUISITION WORKFORCE DEPENDENCY ON E-MAIL FOR FORMAL WORK COORDINATION: FINDINGS AND OPPORTUNITIES FOR WORKFORCE PERFORMANCE IMPROVEMENT THROUGH E-MAIL-BASED SOCIAL NETWORK ANALYSIS KENNETH A. LORENTZEN May 2013 PUBLISHED BY THE DEFENSE ACQUISITION UNIVERSITY PRESS PROJECT ADVISOR: BOB SKERTIC CAPITAL AND NORTHEAST REGION, DAU THE SENIOR SERVICE COLLEGE FELLOWSHIP PROGRAM ABERDEEN PROVING GROUND, MD PAGE LEFT BLANK INTENTIONALLY ii Table of Contents Table of Contents ............................................................................................................................ ii List of Figures ................................................................................................................................ vi Abstract ......................................................................................................................................... vii Chapter 1—Introduction ................................................................................................................. 1 Background and Motivation .................................................................................................
    [Show full text]
  • EDL – Lessons Learned and Recommendations
    ."#!(*"# 0 1(%"##" !)"#!(*"#* 0 1"!#"("#"#(-$" ."!##("""*#!#$*#( "" !#!#0 1%"#"! /!##"*!###"#" #"#!$#!##!("""-"!"##&!%%!%&# $!!# %"##"*!%#'##(#!"##"#!$$# /25-!&""$!)# %"##!""*&""#!$#$! !$# $##"##%#(# ! "#"-! *#"!,021 ""# !"$!+031 !" )!%+041 #!( !"!# #$!"+051 # #$! !%#-" $##"!#""#$#$! %"##"#!#(- IPPW Enabled International Collaborations in EDL – Lessons Learned and Recommendations: Ethiraj Venkatapathy1, Chief Technologist, Entry Systems and Technology Division, NASA ARC, 2 Ali Gülhan , Department Head, Supersonic and Hypersonic Technologies Department, DLR, Cologne, and Michelle Munk3, Principal Technologist, EDL, Space Technology Mission Directorate, NASA. 1 NASA Ames Research Center, Moffett Field, CA [email protected]. 2 Deutsches Zentrum für Luft- und Raumfahrt e.V. (DLR), German Aerospace Center, [email protected] 3 NASA Langley Research Center, Hampron, VA. [email protected] Abstract of the Proposed Talk: One of the goals of IPPW has been to bring about international collaboration. Establishing collaboration, especially in the area of EDL, can present numerous frustrating challenges. IPPW presents opportunities to present advances in various technology areas. It allows for opportunity for general discussion. Evaluating collaboration potential requires open dialogue as to the needs of the parties and what critical capabilities each party possesses. Understanding opportunities for collaboration as well as the rules and regulations that govern collaboration are essential. The authors of this proposed talk have explored and established collaboration in multiple areas of interest to IPPW community. The authors will present examples that illustrate the motivations for the partnership, our common goals, and the unique capabilities of each party. The first example involves earth entry of a large asteroid and break-up. NASA Ames is leading an effort for the agency to assess and estimate the threat posed by large asteroids under the Asteroid Threat Assessment Project (ATAP).
    [Show full text]
  • Inviwo — a Visualization System with Usage Abstraction Levels
    IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS, VOL X, NO. Y, MAY 2019 1 Inviwo — A Visualization System with Usage Abstraction Levels Daniel Jonsson,¨ Peter Steneteg, Erik Sunden,´ Rickard Englund, Sathish Kottravel, Martin Falk, Member, IEEE, Anders Ynnerman, Ingrid Hotz, and Timo Ropinski Member, IEEE, Abstract—The complexity of today’s visualization applications demands specific visualization systems tailored for the development of these applications. Frequently, such systems utilize levels of abstraction to improve the application development process, for instance by providing a data flow network editor. Unfortunately, these abstractions result in several issues, which need to be circumvented through an abstraction-centered system design. Often, a high level of abstraction hides low level details, which makes it difficult to directly access the underlying computing platform, which would be important to achieve an optimal performance. Therefore, we propose a layer structure developed for modern and sustainable visualization systems allowing developers to interact with all contained abstraction levels. We refer to this interaction capabilities as usage abstraction levels, since we target application developers with various levels of experience. We formulate the requirements for such a system, derive the desired architecture, and present how the concepts have been exemplary realized within the Inviwo visualization system. Furthermore, we address several specific challenges that arise during the realization of such a layered architecture, such as communication between different computing platforms, performance centered encapsulation, as well as layer-independent development by supporting cross layer documentation and debugging capabilities. Index Terms—Visualization systems, data visualization, visual analytics, data analysis, computer graphics, image processing. F 1 INTRODUCTION The field of visualization is maturing, and a shift can be employing different layers of abstraction.
    [Show full text]
  • Change in the Wind and Climate at the Exomars 2022 Landing Site in Oxia Planum (Mars)
    52nd Lunar and Planetary Science Conference 2021 (LPI Contrib. No. 2548) 1442.pdf CHANGE IN THE WIND AND CLIMATE AT THE EXOMARS 2022 LANDING SITE IN OXIA PLANUM (MARS). S. Silvestro1,2, D. Tirsch3, A. Pacifici4, F. Salese5,4, D.A. Vaz6, A. Neesemann7, C.I. Popa1, M. Pajola8, G. Franzese1, G. Mongelluzzo1,9, A.C. Ruggeri1, F. Cozzolino1, C. Porto1, F. Esposito1. 1INAF, Osservatorio Astronomico di Capodimonte, Napoli, Italy ([email protected]). 2SETI Institute, Carl Sagan Center, Mountain View, CA, USA. 3Institute of Planetary Research, DLR, Berlin, Germany. 4IRSPS, Università G. D’Annunzio, Pescara, Italy. 5Centro de Astrobiología, CSIC- INTA, Madrid. 6CESR University of Coimbra, Portugal. 7Freie Universitat, Berlin, Germany. 8INAF, Osservatorio Astronomico di Padova, Padova, Italy. 9Department of Industrial Engineering, Università Federico II, Napoli, Italy. Introduction: The ESA/ROSCOSMOS ExoMars Ridges are even visible in association with impact crater 2022 (a rover named “Rosalind Franklin” and a surface ejecta and are superimposed by 10-25 m craters and platform named “Kazachok”) [1] will land in Oxia boulders, so they pre-date these impact events (Fig. 1c). Planum (18.2° N; 24.3° W) to search for signs of past or When associated with crater ejecta, ridges locally show present life on Mars and to perform long-term two different crests (Fig. 2b). Both crests are truncated atmospheric investigations [2,3]. Oxia Planum shows by craters, which suggest that the double crest large outcrops of clay-rich Noachian-aged arrangement was emplaced before the impacts (Fig. 2c). phyllosilicates [4,5]. The clay bearing unit is To better understand the relative age of the ridges, we unconformably overlain by an Amazonian dark resistant mapped their occurrence on 316 craters in the study area unit (Adru), which was interpreted to be remnants of an that we qualitatively classified as relatively Early Amazonian (2.6 Ga) volcanic material [4].
    [Show full text]
  • EUMETSAT Water Vapour Products from New Generation Satellites
    EUMETSAT water vapour imagery products from new generation satellites: development and validation strategy L. Spezzi*, P. Watts, B. Fougnie, J. Chimot, E. Obligis, B. Bojkov *[email protected] 1 EUMETSAT Water Vapor Imagery products @ G-VAP Meeting (Madrid, 13/14 June 2019) Water Vapour Product map (missions & products) EUMETSAT instrumentation: IR and MW sounders, MW imagers, VIS/IR imagers, UV/VIS spectrometers Operational In development Possible Planned only Not yet committed/under study Not Applicable (not yet in plan → room for @EUMETSAT @SAFs @EUMETSAT @EUMETSAT improvement) and/or SAFs and/or SAFs E.g. talk by Sküchler: “Total water vapor column from Sentinel-5P derived by the AMC-DOAS method” Instr./ Metop MSG Sentinel 3 Metop-SG MTG AMSU IASI S5 S4 AVHRR IASI MWR MWI ICI MWS IRS Product MHS SEVIRI OLCI SLSTR VII 3MI NG UVNS FCI UVN Total Colum Water Vapour (clear-sky) Layer Precipitable Water 1=surface to 850hPa 2=850 to 500 hPa 3=500 hPa to TOA Humidity profile 2004 to present 2016 2022+ Time to present Talk by T. August: ‘’IASI retrieval and validation activities at EUMETSAT: Recent updates’’ 2 EUMETSAT Water Vapor Imagery products @ G-VAP Meeting (Madrid, 13/14 June 2019) EUMETSAT sensors for water vapour imagery High spatial resolution Main types of sensors providing imaging measurements for water vapour retrieval Current: • Multispectral Pushbroom and Dual-view radiometer: →Sentinel-3/OLCI and SLSTR ECMWF does not always S3/OLCI (300m) • Geostationary multi-spectral imagers: resolve all features →MSG/SEVIRI Future: • Geostationary multi-spectral imagers: →MTG/FCI • Polar multi-spectral imagers: →EPS-SG/METimage • Multi-directional Polarimeter: • WV concentration in the boundary layer is an indicator of →EPS-SG/3MI mesoscale developments (scale ~4km), e.g.
    [Show full text]
  • Innovation Academy Symposium Brochure
    Stretch & Hold Forth Innovation Academy 7th December 2018 Innovation Academy Programme INTRODUCTION 9.15 Registration 9.45 Welcome Joy Milne ‘NOSE’ MORNING SESSION Chair - Rob Dunn 10.00 Prof Perdita Barran Nose to Diagnose – The search for volatile biomarkers of Parkinson disease in sebum 10.30 Dr Meera Chand Application of nanopore technology 11.00 Olivier Usher – Nesta Flying High 11.30 BREAK Chair – Prof Neil Dalton 11.55 Prof Hal Drakesmith - University of Oxford The importance of being iron-ic 12.15 Prof Josephine Bunch – National Physical Laboratory The Google earth of cancer 12.45 Panel Discussion 1.00 LUNCH Excellence in Pathology – 2018 finalists and voting 2.00 Terry Hunter Quantitative assessment of NFKB transcription factor activity in health and disease 2.05 Younis Khan Luminex-based detection of complement-fixing antibodies using HLA antigens isolated from donor cells – An alternative to the CDC crossmatch 2.10 Rachel Mayhew Functional characterisation of genetic variants using red blood cell ektacytometry AFTERNOON SESSION Chair – Alan Dunlop 2.15 Marie-Jose Weber – PRUH OSNA at the PRUH 2.45 Dr Sally Brady, Karolina Witek, Erin Emmett An introduction to analytical continuous quality improvement: 3 case studies 3.15 Dr Gary Moore - Viapath Viapath and Venom 3.45 Winner of Excellence in Pathology announced 4.00 CLOSE Innovation Academy Dr Dominic Harrington CHIEF SCIENTIFIC OFFICER, VIAPATH It gives me great pleasure to welcome you all to our eighth Innovation Academy Scientific Symposium, ‘Stretch & Hold Forth’. At our seventh symposium we focussed on the advances made in the provision of healthcare since the founding of the National Health Service 70 years ago.
    [Show full text]