Authors: Pallavi Subhraveti Ron Caspi Quang Ong Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_900086655Cyc: Paenibacillus sp. Marseille-P2472 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari 1-(β-D a hydroxamate a C4- glycine betaine an inorganic sn-glycerol ribofuranosyl) phosphonate a nucleoside D-glucose ferrichrome daunorubicin pro a nucleotide Fe 3+ dicarboxylate uracil pro anion 3-phosphate nicotinamide

predicted ABC RS11500 RS05260 RS23740 RS14475 RS23735 RS12925 RS06845 transporter of RS05205 RS23060 RS04870 RS07800 RS00780 RS23910 daunorubicin

a hydroxamate a C4- uracil glycine betaine an inorganic 1-(β-D phosphonate a nucleoside D-glucose ferrichrome a nucleotide sn-glycerol 3+ pro ribofuranosyl) Fe dicarboxylate daunorubicin pro anion 3-phosphate nicotinamide

Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Glycolysis Carbohydrate Degradation an inactive a (2R)-2-hydroxy adenine 1518 / a ribonucleoside guanosine sn-glycerol UDP [2Fe-2S] iron-sulfur cluster biosynthesis a purine oleate KDGP a ribonucleoside superpathway of tetrahydrofolate biosynthesis lipoate biosynthesis guanylyl molybdenum glycolysis I (from glucose 6-phosphate) D-galactose degradation I (Leloir pathway) ribonucleoside a reduced even numbered adenine 1519 in 16S rRNA 2',3'-cyclic 2',3'-cyclic 3'-AMP superpathway of thiamine diphosphate biosynthesis I thiamine salvage II Fatty Acid and Lipid Biosynthesis sucrose degradation III (sucrose invertase) Alcohol Degradation SAM ribonucleoside adenosylcobinamide GTP diphosphate 3-phosphate AMP ribonucleotide- dIDP and incorporation II cofactor biosynthesis triphosphate flavodoxin straight chain acyl-CoA bifunctional 2-keto- 16S rRNA ribonucleoside- phosphate bifunctional 2',3'- monophosphatebifunctional 2',3'- L-glyceraldehyde bifunctional 2',3'- pyridoxal 5'-phosphate biosynthesis I D-glucopyranose reductase anaerobic 5'-triphosphate bifunctional 2,3,4-saturated synthetase: bifunctional bifunctional diphosphate nucleoside- L-cysteine desulfurase 4-amino-2-methyl-5- MoO - β acyl-CoA 4-hydroxyglutarate (adenine(1518)-N(6)/ diphosphate cyclic-nucleotide 2'- cyclic-nucleotide 2'- 3-phosphate cyclic-nucleotide 2'- 2 -D-galactose glycerol and glycerophosphodiester degradation ribonucleoside- 3,4-dihydroxy- metallophosphatase/ reductase diphosphate kinase: GTP octanoate cys pyrimidinemethanol molybdopterin palmitate biosynthesis II (bacteria and plants) 6-phosphate sucrose adenosylcobinamide fatty acidsynthetase: BN6628_RS13935 aldolase/2- adenine(1519)-N(6))- reductase, phosphodiesterase/ phosphodiesterase/ reductase: phosphodiesterase/ D-erythrose lipoate-- fatty acid elongation -- saturated triphosphate kinase/ 2-butanone- 5'-nucleotidase: subunit beta: BN6628_RS17985 cysteine desulfurase: bifunctional cofactormolybdopterin- aldose 1-epimerase: BN6628_RS13935 long-chain fatty keto-3-deoxy-6- dimethyltransferase adenosylcobalamin- 3'-nucleotidase: 3'-nucleotidase: BN6628_RS07035 3'-nucleotidase: 4-phosphate protein ligase: cysteine desulfurase: glucose-6-phosphate reductase adenosylcobinamide- 4-phosphate BN6628_RS19015 BN6628_RS02700 nucleoside- BN6628_RS06940 hydroxymethylpyrimidine guanine BN6628_RS17005 beta-fructosidase: a glycerophosphodiester acid--CoA ligase: phosphogluconate RsmA: dependent: BN6628_RS21385 BN6628_RS01730 BN6628_RS01730 GTP BN6628_RS05835 BN6628_RS06940 an acetoacetyl-[acp] isomerase: activating phosphate long-chain fatty synthase/GTP L-glyceraldehyde ribonucleoside- diphosphate kinase: [+ 3 isozymes] a [lipoyl-carrier aldose 1-epimerase: BN6628_RS07225 aldolase: 6 BN6628_RS252001518 adenosine cyclohydrolase kinase/ dinucleotide an acetoacetyl-[acp] BN6628_RS06205 glycerol an active acid--CoA ligase: N -dimethyladenine BN6628_RS17250 bifunctional 2',3'- bifunctional 2',3'- 3-phosphate bifunctional 2',3'- 6 BN6628_RS05780 protein: nrdG guanylyltransferase: a (R)-2-hydroxy cyclohydrolase II: diphosphate BN6628_RS10395 protein] N - [+ 3 isozymes] BN6628_RS20210 BN6628_RS18565 6 1519 an S-sulfanyl-[L- I FolE: folE an [L-cysteine phosphomethylpyrimidine biosynthesis 3-oxoacyl-ACP glycerophosphodiester a flavodoxin ribonucleoside BN6628_RS07225even numbered /N -dimethyladenine 2,5-diamino-6-BN6628_RS10165 a 2'- [+ 2 isozymes] cyclic-nucleotide 2'- cyclic-nucleotide 2'- reductase: cyclic-nucleotide 2'- 7,8- 4-phospho- octanoyl-L-lysine a ThiS sulfur- met 5'-deoxyadenosine a purine BN6628_RS05880adenosyl- diphosphate AMP oleoyl-CoA D-glyceraldehyde reductase dITP cysteine desulfurase] desulfurase]-S- kinase: thiD protein B: mobB reductase: α-D-galactose β-D-fructofuranose D-glucopyranose phosphodiesterase: glycerol semiquinone triphosphate diphosphate AMP straight chain pyruvate in 16S rRNA (5-phospho-D- deoxyribonucleoside phosphodiesterase/ phosphodiesterase/ BN6628_RS13035 phosphodiesterase/ dihydroneopterin D-erythronate lipoyl carrier protein F6P ribonucleoside cobinamide 3-phosphate L-glyceraldehyde subunit alpha: synthase: sulfanyl-L-cysteine bifunctional molybdenum cofactor BN6628_RS05720 BN6628_RS17790 kinase: reductase 2,3,4-saturated formate ribosylamino) 5'-diphosphate 3'-nucleotidase: 3'-nucleotidase: 3'-nucleotidase: BN6628_RS02705 3'-triphosphate glucokinase: 5'-diphosphate phosphate 3-phosphate BN6628_RS21385 lipA AIR cysteine desulfurase: ThiS hydroxymethylpyrimidine guanylyltransferase: [+ 8 isozymes] galactokinase: fructokinase: [+ 2 isozymes] glpK fatty acyl CoA pyrimidin- BN6628_RS01730 BN6628_RS21385 guanylyl a (3R)-3- fructose-1,6- BN6628_RS00955 a ribonucleoside dUDP a [lipoyl-carrier BN6628_RS06940 adenylyltransferase: kinase/ BN6628_RS22405 a 3-oxoacyl-[acp] 6-phosphofructokinase: BN6628_RS07045 BN6628_RS01620 4(3H)-one 3'-GMP an S-sulfanyl-[cysteine 6 phosphomethylpyrimidine molybdenum hydroxybutanoyl- bisphosphatase: 3'-phosphate adenosine (3R)-3-hydroxy-2-oxo- protein]-N - [+ 3 isozymes] BN6628_RS11410 phosphomethylpyrimidine pfkA D-glucopyranose sn-glycerol desulfurase]-[disordered- synthase ThiC: a [ThiI sulfur- a carboxy- cofactor [acp] BN6628_RS12785 α-D-galactose fructokinase: 7,8- 4 phosphooxybutanoate lipoyl-L-lysine kinase: thiD UDP-α-D-glucose 6-phosphate 3-phosphate form scaffold BN6628_RS01855 carrier protein]-S- adenylated-[ThiS 3-hydroxyacyl- 1-phosphate BN6628_RS04705 dihydroneopterin 3-phosphoserine/ fructose β-D-fructose 1,6- protein] complex 3'-phosphate sulfanyl-L-cysteine sulfur-carrier protein] HMP-P [acyl-carrier- glucose-6-phosphate glycerol-3- cysteine desulfurase: phosphohydroxythreonine D-glyceraldehyde bis(guanylyl molybdenum 3-oxoacyl-ACP bisphosphate bisphosphate undecaprenyl- a glycopeptide- a 2-methyl a [dinitrogen adenosine HMP-P protein] isomerase: phosphate D-cellobiose a (6S)-5- adenosyl- 4-hydroxy-2- a ribonucleoside a nucleoside dCDP BN6628_RS06940 transaminase: 3-phosphate cofactor) biosynthesis reductase: aldolase: diphospho-N- D-mannosyl-N 4 branched 2,3,4- Glu reductase]-N ω -α- 2',3'-cyclic DHAP 3'-GMP chorismate adenylate:persulfide tyr bifunctional dehydratase BN6628_RS18090 BN6628_RS05780 dehydrogenase: formyltetrahydrofolate cobinamide GTP oxoglutarate 3'-phosphate diphosphate ribonucleotide- IDP [+ 3 isozymes] BN6628_RS12150 bifunctional 1-deoxy-D-xylulose- MoO - β-ketoacyl- BN6628_RS13555 acetylmuramoyl- UDP-N-acetyl- -(N-acetyl-D- saturated fatty acid cellobiose ( ADP-D-ribosyl) bifunctional 2-keto- monophosphate nucleoside- NAD(P)H- transferase: hydroxymethylpyrimidine 2 FabZ: fabZ BN6628_RS24820 acyl-CoA bifunctional phosphate bifunctional 2',3'- bifunctional 2',3'- bifunctional 2',3'- a [cysteine desulfurase]- hydroxymethylpyrimidine 5-phosphate fructose-1,6- γ α glucosaminyl) phosphorylase: dependent glycerol- diphosphate nucleoside- 7,8- aminodeoxychorismate/ 3-phosphoserine/ BN6628_RS11410 kinase/ molybdopterin ACP [+ 8 isozymes] F6P L-alanyl- -D- -D-glucosamine synthetase: folylpolyglutamate -L-arginineADP-ribosyl- bifunctional 4-hydroxyglutarate cyclic-nucleotide 2'- cyclic-nucleotide 2'- diphosphate kinase: cyclic-nucleotide 2'- S-sulfanyl-[disordered- kinase/ synthase: a (2E)-but- bisphosphate undecaprenyldiphospho- -asparagineendo-beta-N- BN6628_RS18465 3-phosphate reductase diphosphate kinase: dihydroneopterin phosphohydroxythreonine cofactor synthase: DHAP glutamyl-L-lysyl- 2 [dinitrogen adenosylcobinamide aldolase/2- phosphodiesterase/ BN6628_RS10395 anthranilate synthase phosphomethylpyrimidine acetylglucosaminidase: BN6628_RS13935 synthase/ phosphodiesterase/ phosphodiesterase/ subunit beta: BN6628_RS17985 form scaffold 10 phosphomethylpyrimidine BN6628_RS09935 2-enoyl-[acp] a (3R)-3- DHAP aldolase, muramoylpentapeptide beta-N- cellobiose dehydrogenase: component II: transaminase: N -formyl-tetrahydrofolate biosynthesis kinase: thiD a 2,3,4-saturatedfabF L-arabinose D-alanyl-D-alanine ditrans,octacis- long-chain fatty dihydrofolate reductase] kinase/ keto-3-deoxy-6- 3'-nucleotidase: 3'-nucleotidase: nucleoside- 3'-nucleotidase: protein] complex dihydroneopterin kinase: thiD a thiocarboxy- bis(molybdenum hydroxyacyl-[acyl- class II: fba acetylglucosaminyltransferase: BN6628_RS19800 phosphorylase: BN6628_RS10315 BN6628_RS02700 nucleoside- cysteine desulfurase: BN6628_RS25375 BN6628_RS19305 1-deoxy-D-xylulose 2-iminoacetate crotonyl-[acyl-carrier- fatty acyl-[acp] degradation I undecaprenyldiphospho- acid--CoA ligase: synthase: hydrolase: adenosylcobinamide- phosphogluconate BN6628_RS21385 BN6628_RS01730 diphosphate kinase: BN6628_RS01730 aldolase: folB [ThiS-Protein] bifunctional 5-(2-hydroxyethyl) cofactor) 3-hydroxyacyl-carrier protein] murG endo-beta-N- BN6628_RS23085 sn-glycerol ribonucleoside- diphosphate kinase: 4-phosphooxy- bifunctional 5-phosphate protein] reductase: β BN6628_RS07225 a [dinitrogen BN6628_RS04135 phosphate aldolase: BN6628_RS17985 BN6628_RS06940 6-(hydroxymethyl) 4-amino-4- a tetrahydrofolate hydroxymethylpyrimidine -4-methylthiazole [acyl-carrier- triose-phosphate N-acetyl-(N-acetyl- -D- acetylglucosaminidase: a 2-methyl α-D- BN6628_RS06520 bifunctional 2',3'- bifunctional 2',3'- bifunctional 2',3'- diphosphate BN6628_RS10395 L-threonine hydroxymethylpyrimidine molybdenum cofactor BN6628_RS03485 L-arabinopyranose UDP a glycopeptide- a (6S)-5- reductase]- ADP-D-ribose guanylyltransferase: BN6628_RS18565 a nucleoside 3-phosphate [+ 3 isozymes] -7,8-dihydropterin deoxychorismate kinase/ protein] isomerase: L-arabinose Amine and Polyamine glucosaminyl)muramoyl- N-acetyl-D-BN6628_RS21140 branched D-glucopyranose glucopyranose cyclic-nucleotide 2'- cyclic-nucleotide 2'- cyclic-nucleotide 2'- reductase an S-sulfanyl-[cysteine kinase/ thiazole synthase: guanylyltransferase: γ D-mannosyl- AMP diphosphate formyltetrahydrofolate L-arginine BN6628_RS05880 triphosphate ITP 4-amino-4- phosphomethylpyrimidine dehydratase BN6628_RS01040 Degradation L-alanyl- -D-glutamyl-L- glucosamine- 2,3,4-saturated 1-phosphate adenosylcobinamide- pyruvate glyoxylate phosphodiesterase/ phosphodiesterase/ phosphodiesterase/ desulfurase]-S- 2-amino-4-hydroxy-6- D-glyceraldehyde BN6628_RS11405 BN6628_RS22405 a butanoyl-[acp] isomerase: 4 subunit alpha: deoxychorismate pyruvate phosphomethylpyrimidine kinase: thiD lysyl-D-alanyl-D-alanine N -N-acetyl- asparagine fatty acyl-CoA GDP 3'-nucleotidase: 3'-nucleotidase: 3'-nucleotidase: sulfanyl-[disordered- hydroxymethyldihydropteridine 3-phosphate 4-methyl-5-(2- bis(guanylyl FabZ: fabZ BN6628_RS15840 BN6628_RS02705 lyase: kinase: thiD 2-[(2R,5Z)-2-carboxy- UDP-glucose:α- N-acetylglucosamine D-glucosamine BN6628_RS01730 BN6628_RS21385 BN6628_RS21385 form scaffold diphosphokinase: folK (2S)-2-amino-3-oxo-4- phosphooxyethyl) molybdopterin β-ketohexanoyl- D-glyceraldehyde L-ribulose CDP BN6628_RS25380 1-deoxy-D-xylulose- methionine 4-methylthiazol-5(2H)- HMP-PP D-galactose- UDP-glucose degradation I protein] complex (7,8-dihydropterin- phosphooxybutanoate synthase: metH HMP-PP thiazole cofactor) [acp] 3-phosphate a ribonucleoside 3'-AMP 5-phosphate ylidene]ethyl phosphate 1-phosphate 4-epimerase ribulokinase: N-acetyl-D- guanosine cysteine desulfurase: 6-yl)methyl 4-aminobenzoate synthase: fabF synthase: glyceraldehyde- uridylyltransferase: GalE: galE BN6628_RS15825 glucosamine BN6628_RS06940 diphosphate thiamine phosphate 3-oxoacyl-[acyl- 2,3,4-saturated- a trans-2- BN6628_RS09935 thiamine phosphate a 2,3,4-saturated 3-phosphate α-D-glucopyranose BN6628_RS07055 L-ribulose 5- 6-phosphate [+ 3 isozymes] synthase: carrier-protein] fatty-acid-[acp] enoyl-[acyl- UDP-α-D-galactose N-acetylglucosamine- a [cysteine dihydropteroate 1-deoxy-D- 3-amino-1- synthase: BN6628_RS11420 fatty acyl-[acp] reductase: carrier protein] dehydrogenase: 1-phosphate phosphate 6-phosphate reductase: an odd numbered a 3-methyl- 4-amino-4- a guanine 34 3-oxopentanoyl- D-ribulose (4S)-4-hydroxy- cytidine (2R,3S)-3- an (11Z)-3- a [2-oxoglutarate (S)-4-amino-5- desulfurase]-(S- xylulose 5- hydroxyacetone dihydrofolate BN6628_RS11420 molybdenum cofactor biosynthesis lipoate salvage I gap 2503 3'-cmp synthase: folP BN6628_RS05070 L-ribulose-5- D-glucosaminedeacetylase: nagA adenine in 23S rRNA straight chain branched 2,3,4- deoxy-α-L- queuine 2',3'-cyclic oxooctadec- dehydrogenase sulfanyl) -[disordered- phosphate 1-phosphate reductase: BN6628_RS16815 phosphoglucomutase: ribose phosphorylation α-D-Kdo-(2->4) in tRNA CoA 5-phosphate 2-oxoglutarate ITP isopropylmalate oxopentanoate 2 NAD biosynthesis thiamine phosphate 4- 6-phosphate 23S rRNA (adenine(2503) 2,3,4-saturated saturated fattyacyl-CoA acid arabinopyranosyl tRNA guanosine(34) acetyl-CoA bifunctional bifunctional 2-keto- monophosphate 3-isopropylmalate 11-enoyl-[acp]3-oxoacyl-ACP bifunctional 2',3'- E2 protein] N 6 glutamate-1- form scaffold 7,8- BN6628_RS11475 a 3-oxohexanoyl- BN6628_RS22165 -α-D-Kdo- bifunctional 2',3'- XTP/dITP diphosphatase: I (from aspartate) thiamine phosphate phosphate (R)-lipoate 13-DPG epimerase: -C(2))-methyltransferase fatty acidacyl-CoA synthetase: ditrans,octacis transglycosylase acetyltransferase: 3,4-dihydroxy- 4-hydroxyglutarate dehydratase reductase: cyclic-nucleotide 2'- -dihydrolipoyl- semialdehyde- protein] complex dihydropteroate serine [acp] 2,3,4-saturated fatty chitobiose degradation β-D-ribopyranose (2->6)-lipid A cyclic-nucleotide 2'- BN6628_RS06305 dihydrolipoyl [+ 2 isozymes] ATP lipoate-- D-glucopyranose araD RlmN: BN6628_RS09405 synthetase: BN6628_RS13935 -undecaprenyl Tgt: BN6628_RS07215 2-butanone- aldolase/2- small subunit: leuD phosphodiesterase/ L-lysine 2,1- hydroxymethyltransferase: GTP acyl-[acp]:NAD+ D-ribose pyranase: 4-amino-4-deoxy- phosphodiesterase/ BN6628_RS05720 dehydrogenase: bifunctional protein ligase: 3-oxoacyl-ACP 6-phosphate D-xylulose BN6628_RS13935 phosphate BN6628_RS06785 4-phosphate keto-3-deoxy-6- nucleoside triphosphate 3'-nucleotidase: aminomutase: asp cys oxidoreductase: 3-phosphoglycerate N,N'- α 23S rRNA (adenine(2503) long-chain fatty L-arabinose acetyl-CoA C- 3-isopropylmalate a (3R,11Z)-3-[+ 8 isozymes] folylpolyglutamate pyridoxine BN6628_RS12155 molybdopterin- BN6628_RS05835 reductase: 5-phosphate BN6628_RS14675 -D-glucosamine long-chain fatty synthase/GTP phosphogluconate 3'-nucleotidase: pyrophosphohydrolase: BN6628_RS01730 lpdA hemL L-aspartate a 7,8-dihydrofolate gcv system:a 5-methyltetrahydrofolate lpdA GTP 3',8- BN6628_RS03485 kinase: diacetylchitobiose β -C(2))-methyltransferase acid--CoA ligase: 4'-transferase:α-L-Ara4N-α- a queuosine 34 acyltransferase: dehydratase hydroxyoctadec- synthase/ 5'-phosphate serine synthase lipoyl-adenylate BN6628_RS05720 -D-ribofuranose 6-phosphate acid--CoA ligase: di-trans,octa-cis guanine cyclohydrolase II: aldolase: BN6628_RS01730 BN6628_RS25275 dihydrolipoyl a [cysteine desulfurase]- oxidase: nadB cysteine desulfurase: cyclase thiamine BN6628_RS24075 6'-phosphate RlmN: BN6628_RS23575 BN6628_RS07225 BN6628_RS18660Kdo-(2->4)-α- in tRNA BN6628_RS13930 large subunit: leuC 11-enoyl-[acp] bifunctional 2',3'- [+ 2 isozymes] [scaffold protein- dihydrofolate hydroxymethyltransferase: BN6628_RS06940 adenylyltransferase: [+ 8 isozymes] glucosamine- BN6628_RS07225an odd numbered a 3-methyl- -undecaprenyl BN6628_RS10165 BN6628_RS18565 bifunctional 2',3'- IMP (2S)-2- dehydrogenase: 2-iminosuccinate thiamine diphosphate MoaA: moaA diphosphate lipoate-- phosphoglycerate 2503 Kdo-(2->6)-[P4'- propanoyl-CoA acetyl-CoA cyclic-nucleotide 2'- a [2-oxoglutarate 5-aminolevulinate synthase: BN6628_RS22290 BN6628_RS11410 a (3R)-3- N-monoacetylchitobiose 6-phosphate a 2-methyladenine in 23S rRNA 5'-deoxyadenosine met straight chain branched phosphate 1-deoxy-L- cyclic-nucleotide 2'- isopropylmalate lpdA (2Fe-2S)] complex thymidylate [+ 3 isozymes] (8S)-3',8-cyclo-7,8- protein ligase: kinase: pgk maltose degradation diphosphate AMP diphosphate AMP α-L-ara4N]-lipid A pyruvate glyoxylate phosphodiesterase/ dehydrogenase an [L-cysteine a carboxy-adenylated hydroxyhexanoyl- 6'-phosphate deaminase: 2,3,4-saturated 2,3,4-saturated glycero-tetrulose formate 6 BN6628_RS06520 quinolinate synthase: dihydroguanosine BN6628_RS05835 D-mannose degradation phosphodiesterase/ 3'-nucleotidase: E2 protein] N [acp] CDP-diacylglycerol biosynthesis III α nagB fatty acyl CoA fatty acyl-CoA 4-phosphate maltose RS02385 maltose 7,8-dihydrofolate synthase NadA: BN6628_RS11470 desulfurase]-S- [small subunit of 5'-triphosphate a [lipoyl-carrier 3-phospho- 6-phospho-beta- -D-ribofuranose 3'-nucleotidase: BN6628_RS21385 -lipoyl-L-lysine PLP 3-hydroxyacyl- maltose monoglutamate BN6628_RS25340 sulfanyl-L-cysteine molybdopterin synthase] cyclic pyranopterin protein]-N 6 - D-glycerate glucosidase: BN6628_RS21385 a [co-chaperone]- thymidylate maltose D-mannopyranose ribokinase: F6P cytidine monophosphate lipoyl-L-lysine [acyl-carrier- DHAP BN6628_RS12230 3'-cmp [scaffold protein- synthase: phosphorylase: 6-phosphate rbsK quinolinate synthase protein] 2,3-bisphosphoglycerate- 2,3- [+ 2 isozymes] mannose-6- thiamine RS19845 thiamine (2Fe-2S)] complex BN6628_RS12865 BN6628_RS02350 α MoaC: moaC dehydratase NAD(P)H- an acyl-[acyl- independent diphosphoglycerate- β-D-glucopyranose N-acetyl-D- phosphate -D-ribose nicotinate- α ω a (7Z,10Z,13Z,16Z uridine 2'3'-cyclic N-acetyl-D- an [amino group carrier bifunctional a (6S)-5- a thiocarboxylated FabZ: fabZ dependent glycerol- carrier protein] phosphoglycerate dependent 1-phosphate glucosamine D-glucosamine isomerase, 5-phosphate ditrans,octacis- a very-long- , -9Z- an [apo BCAA a cis-delta15-3- 3'-UMP a [lipoyl-carrier a 7,8-dihydrofolate a uracil in DNA adenosylcobinamide a uridine in tRNA γ 6 acetyl-CoA nucleotide heme b biosynthesis [small subunit of cyclic pyranopterin 3-phosphate mutase: phosphoglycerate class I: manA a peptidoglycan with undecaprenyldiphospho- chain fatty acid octadecenedioate (S)-3-methyl-2- dehydrogenase ,19Z)-3-oxodocosa- monophosphate mannosamine protein]-C-terminal- - protein]-N -[(R) methylenetetrahydrofolate formyltetrahydrofolate a (2E)-hex- beta- 6-phosphate Aromatic Compound oxo-C34:1-[acp] 2+ 2+ diphosphorylase phosphate γ β long-chain fatty long-chain fatty 6 7,10,13,16,19-pentaenoyl-[acp] uracil-DNA bifunctional tRNA dihydrouridine bifunctional 2',3'- 6-phosphate (L-glutamyl)-L-glutamate bifunctional 2',3'- acetyl-CoA Zn RS17115 Zn a [chaperone-ATP]- dihydrofolate I (aerobic) dehydrogenase/ 5-formyltetrahydrofolate molybdopterin synthase] dehydrogenase: BN6628_RS01045 mutase: gpmA mannose-6- (L-alanyl- -D-glutamyl- N-acetyl-(N-acetyl- -D- oxopentanoate E2 protein] N 3-oxoacyl-ACP putative N- 3-oxoacyl-ACP -dihydrolipoyl]- (carboxylating) 2-enoyl-[acp] phosphoglucomutase: Degradation acid--CoA ligase: acid--CoA ligase: branched-chain glycosylase: adenosylcobinamide synthase DusB: cyclic-nucleotide 2'- cyclic-nucleotide 2'- carboxylase, [co-chaperone]- reductase: methenyltetrahydrofolate cyclo-ligase: BN6628_RS10315 phosphate L-lysyl-D-alanyl-D- glucosaminyl)muramoyl- -lipoyl-L-lysine reductase: acetylmannosamine- acetylglutamate reductase: L-lysine dihydrolipoyl : nadC thiazole biosynthesis II (aerobic bacteria) hexanoyl-[acyl- pgmB γ BN6628_RS07225 BN6628_RS07225 alpha-keto acid BN6628_RS08975 kinase/ BN6628_RS25405 phosphodiesterase/ phosphodiesterase/ biotin carboxyl [scaffold protein- BN6628_RS11475 uroporphyrinogen-III cyclohydrolase FolD: BN6628_RS05135 sn-glycerol 2-phospho- isomerase: xylose 4,5-dichlorocatechol alanine) pentapeptide L-alanyl-peptidoglycan-D-glutamyl-L- BN6628_RS05720 6-phosphate kinase: argB BN6628_RS05720 dehydrogenase: (2Fe-2S)] complex uroporphyrinogen carrier-protein] an acyl phosphate D-glycerate [+ 2 isozymes] lysyl-D-alanyl-D-alanine acyl-CoA acyl-CoA dehydrogenase uracil-DNA adenosylcobinamide- tRNA-dihydrouridine 3'-nucleotidase: 3'-nucleotidase: lpdA carrier [+ 2 isozymes] NaMN a 5,10- BN6628_RS09910 a 5,10- 3-phosphate BN6628_RS13480 degradation I degradation a peptidoglycan with glycosyltransferase: a (3R,7Z,10Z,13[+Z,16 8 isozymes]Z 2-epimerase: an [amino group carrier a cis-delta15-3-[+ 8 isozymes] a purine RS02900 a purine decarboxylase: reductase: β-D-glucose di-trans,octa-cis synthetase: synthetase: subunit E2: glycosylase: phosphate synthase: BN6628_RS01730 BN6628_RS01730 protein: accB methylenetetrahydrofolate methenyltetrahydrofolate a ThiS sulfur- F6P (L-alanyl-γ-D-glutamyl- BN6628_RS07005 an [apo BCAA dehydrogenase ,19Z)-3-hydroxydocosa- N-acetyl-D- BN6628_RS20965 protein]-C-terminal- hydroxyC34:1- dihydrolipoyl BN6628_RS17810 molybdopterin cys BN6628_RS03485 phosphopyruvate 6-phosphate D-xylopyranose 4,5-dichlorobenzene- -undecaprenyl BN6628_RS13935 BN6628_RS13935 BN6628_RS22700 BN6628_RS01130 guanylyltransferase: BN6628_RS03945 a tetrahydrofolate nicotinate-nucleotide carrier protein L-lysyl-D-alanyl-D- E2 protein] N 6 -S-[2- 7,10,13,16,19-pentaenoyl-[acp] bifunctional 2',3'- glucosamine γ-(5-phospho-L- [acp] bifunctional 2',3'- dehydrogenase: [+ 3 isozymes] coproporphyrinogen III bifunctional acyl-phosphate hydratase: trehalose degradation I (low osmolarity) xylose 1,2-diol diphosphate ω-carboxy- an apyrimidinic BN6628_RS05880 a 5,6-dihydrouridine adenylyltransferase: cysteine desulfurase: ThiS alanine) pentapeptide a very-long-chain methylbutanoyl]dihydrolipoyl- uracil cyclic-nucleotide 2'- 6-phosphate glutamyl)-L-glutamate cyclic-nucleotide 2'- a [lipoyl-carrierlpdA malonyl-CoA a [chaperone- methylenetetrahydrofolate a hexanoyl-[acp] glycerol 3- BN6628_RS01050 isomerase: AMP diphosphate AMP diphosphate (9Z)-octadec- site in DNA adenosyl-cobinamide in tRNA 6 L-cystine RS02320 L-cystine nadD BN6628_RS06940 adenylyltransferase: α,α-trehalose fatty acyl-CoA L-lysine phosphodiesterase/ phosphodiesterase/ protein]-N - an [2Fe-2S] ADP]-[disordered- dehydrogenase/ phosphate xylA 2,3-dichloro- 9-enoyl-CoA phosphate nicotinate adenine BN6628_RS11410 phosphoenol 6-phosphate 3'-nucleotidase: 3'-nucleotidase: lipoyl-L-lysine cluster protein form scaffold phosphopantothenate biosynthesis I di-trans,poly-cis methenyltetrahydrofolate molybdopterin [+ 3 isozymes] 3-oxoacyl-[acyl- acyltransferase: D-xylulose cis,cis-muconate dinucleotide an [L-cysteine a carboxy- pyruvate BN6628_RS21385 BN6628_RS21385 protein] complex -undecaprenyl cyclohydrolase FolD: adenine dinucleotide carrier-protein] plsY heme a biosynthesis NAD+ synthetase, desulfurase]-S- adenylated-[ThiS alpha,alpha- 3'-UMP uridine chloride RS15880 chloride protoporphyrinogen IX phosphate biosynthesis BN6628_RS09910 molybdopterin reductase: xylulokinase: NH3-dependent: 3-methyl-2-oxobutanoate sulfanyl-L-cysteine sulfur-carrier protein] D-glyceraldehyde a 1-acyl-sn phosphoenolpyruvate phosphotrehalase: (2E,6E)-farnesyl folate polyglutamylation molybdenumtransferase BN6628_RS16815 xylB BN6628_RS03355 protoporphyrinogen IPP 10 3-phosphate synthase: ferroheme b 3-methyl-2-oxobutanoate diphosphate an N -formyltetrahydrofolate gly β -glycerol 3- treC D-xylulose 2-chloro-2-(2-chloro- MoeA: BN6628_RS11610 cysteine -ketooctanoyl- BN6628_RS12985 ditrans,octacis- an [apo BCAA (+)-7-epi- 2251 527 an [Fe-S cluster a [disordered- protoheme IX oxidase: phosphate pyruvate a single + guanosine a guanine a cis-delta11-3- + hydroxymethyltransferase: 1-deoxy-D-xylulose- [acp] 5-phosphate 5-oxofuran-2-yl)acetate an alkylated DNA ammonium NAD(P) H O adenosylcobinamide H O [DNA] (R)-NADPHX (S)-NADPHX roseoflavin an anion RS23880 an anion biosynthesis form [Fe-S] cluster farnesyltransferase: NAD BN6628_RS17800 di-trans,octa-cis a tetrahydrofolate MoO -molybdopterin desulfurtrase: kinase: pyk stranded DNA DL-allothreonine undecaprenyldiphospho- 4-methyl-2- dehydrogenase 2 jasmonoyl-CoA 2 in 23S rRNA in 16S rRNA panB 2 5-phosphate glycine 1-acyl-sn-glycerol- phosphoenolpyruvate oxo-C30:1-[acp] ATP -undecaprenyl synthase: fabF glucokinase: exodeoxyribonuclease oxopentanoate 6 DNA-3- nitrite reductase bifunctional acyl-CoA 16S rRNA DNA polymerase 5'-phosphate chaperone]-ATP scaffold protein] BN6628_RS20200 protoporphyrinogen cofactor BN6628_RS08035 oxidase 3-phosphate synthase: serine N-acetyl-(N- E2 protein] N 23S rRNA 3-oxoacyl-ACP bifunctional bifunctional diphosphate synthase: BN6628_RS00955 fructose degradation VII large subunit: branched-chain methyladenine (NAD(P)H) small adenosylcobinamide thioesterase: (guanine(527)-N(7) domain-containing bifunctional ferroheme o oxidase: 2-dehydropantoate ThiO: thiO a 3-oxooctanoyl- acyltransferase: BN6628_RS23160 D-glucopyranose D-glucopyranose hydroxymethyltransferase: acetylglucosaminyl) -lipoyl-L-lysine (guanosine(2251) reductase: ADP-dependent ADP-dependent undecaprenyl- bifunctional serine BN6628_RS09935 BN6628_RS09915 alpha-keto acid glycosylase: subunit: nirD kinase/ BN6628_RS18880 )-methyltransferase protein: riboflavin BN6628_RS18610 a thiocarboxy- [acp] BN6628_RS10295 6-phosphate β-D-fructofuranose 5-chloro-trans BN6628_RS12155 muramoyl-L-alanyl- -2'-O)- BN6628_RS05720 NAD(P)H-hydrate NAD(P)H-hydrate cyanate RS18600 cyanate 2-dehydropantoate diphosphate folylpolyglutamate hydroxymethyltransferase: 1-deoxy-D-xylulose a 1,2-diacyl- γ dehydrogenase BN6628_RS00400 nitrite reductase adenosylcobinamide- acyl-CoA methyltransferase RsmG: BN6628_RS14880 dehydratase/ dehydratase/ kinase/FAD heme A synthase: [ThiS-Protein] 2-iminoacetate 3-oxoacyl-ACP 1-phosphate -dienelactone exodeoxyribonuclease serine -D-isoglutaminyl- a DNA containing a cis-delta11-3-[+ 8 isozymes] thioredoxin 2-reductase: phosphatase: synthase/ BN6628_RS12155 an N 10 - 5-phosphate pyruvate β subunit E2: an alkylated phosphate BN6628_RS25015 synthetase: NAD BN6628_RS20135 protoporphyrin IX sn-glycerol 1-phosphofructokinase: VII small subunit: xseB hydroxymethyltransferase: N-( -D-asparaginyl)peptidoglycan an apurinic/ (NAD(P)H) small thioesterase: RlmB: 7 [+ 2 isozymes] NAD(P)H-hydrate NAD(P)H-hydrate pathway BN6628_RS19010 dihydrofolate serine reductase: dienelactone a [apo BCAA dehydrogenaseBN6628_RS22700 nucleobase guanylyltransferase: an N - hydroxyC30:1- BN6628_RS08115 formyltetrahydrofolate 3-phosphate pfkB a single-stranded a ribonucleoside di-trans,octa-cis-L-lysyl-D-alaninea peptidoglycan 6 subunit: nirD BN6628_RS04515 BN6628_RS21645 527 a nucleoside 5'- epimerase: epimerase: ribF phosphorylation and thiazole synthase: BN6628_RS05720 β-D-fructose 1,6- hydrolase: BN6628_RS22290 glycosyltransferase: E2 protein] N -S-[3- apyrimidinic site 2-O- methylguanine [acp] roseoflavin adenine nitrate nitrate 2+ 2+ ferroheme i ferrochelatase: synthase: hydroxymethyltransferase: oligodeoxyribonucleotide 5'-monophosphate BN6628_RS05880 (+)-7-epi- monophosphate Mn RS15455 Mn β-alanine undecaprenyl- bifunctional phosphatidate -undecaprenyl BN6628_RS07005dimer nitrite 2251 BN6628_RS02670 BN6628_RS02670 RS20880 transhydrogenation an oxidized (R)-pantoate BN6628_RS06520 BN6628_RS11405 [+ 8 isozymes] bisphosphate BN6628_RS12620 gly acetaldehyde methylbutanoyl]dihydrolipoyl- methylguanosine in 16S rRNA dinucleotide nitrite nitrite BN6628_RS17805 diphosphate BN6628_RS22290 folylpolyglutamate cytidylyltransferase: diphosphate (tetrapeptide) adenosyl-cobinamide jasmonate + thioredoxin a (3R)-3- L-lysine in 23S rRNA (S)-NADPHX NADPH NAD heme A synthase: deferrochelatase/ lipoate biosynthesis BN6628_RS16410 5-chloromaleylacetate phosphate phosphatase: synthase/ 2-[(2R,5Z)-2-carboxy- hydroxyoctanoyl- glycolysis III (from glucose) Nucleoside and Nucleotide Degradation NAD kinase: BN6628_RS20135 peroxidase EfeB: pantoate--beta-alanine a 5,10- and incorporation I BN6628_RS23510 a tetrahydrofolate dihydrofolate 4-methylthiazol-5(2H)- [acp] a CDP- predicted BN6628_RS20265 thioredoxin- BN6628_RS03160 ligase: BN6628_RS10610 di-trans,octa-cis methylenetetrahydrofolate a sugar RS18540 a sugar hydroxyferroheme i synthase: ylidene]ethyl phosphate 3-hydroxyacyl- diacylglycerol D-glucopyranose superpathway of pyrimidine β a long-linear (1S,2R)-1- ABC NADP + disulfide -undecaprenyl phosphoenol an [HPr]- an N-acetyl- - dihomo γ- a double-stranded D-ribose D-ribose bifunctional BN6628_RS06520 an octanoyl-[acp] [acyl-carrier- superpathway of purine deoxyribonucleosides degradation (15Z)-tetracosenoate methyl red α chitin H O a cis-delta17-3- (S)-NADHX transporter reductase: ferroheme b phosphate lipoate-protein deoxyribonucleosides degradation (2Z,4Z)-2-chloro- pyruvate L-histidine D-hexosaminide -D-glucan dAMP linolenoyl-CoA 2 oligonucleotide C-(indol-3- Ins(1)P FMN ATP folylpolyglutamate an N 10 - protein] glucokinase: beta-N- glycogen/starch/ beta-N- dITP ser oxo-C36:1-[acp] of D-ribose NAD/NADP (R)-pantothenate acyl-CoA synthetase: phosphoenolpyruvate- FMN-dependent acyl-CoA bifunctional yl)glycerol 3-oxoacyl-ACP inositol bifunctional trxB synthase/ formyltetrahydrofolate ligase B: dehydratase BN6628_RS00955 2'-deoxycytidine 3-hydroxyhexa- acetylhexosaminidase: alpha-glucan acetylhexosaminidase: XTP/dITP diphosphatase: predicted transhydrogenase a [lipoyl-carrier 2-(2-carboxy-4- BN6628_RS13935 -protein NADH-azoreductase: thioesterase: oligoribonuclease/ 3-phosphate tryptophan reductase: monophosphatase: ADP-dependent bifunctional serine serine thioredoxin- pantothenate kinase: thiamine salvage III dihydrofolate BN6628_RS10025 FabZ: fabZ 2'-deoxyguanosine 2,4-dienedioate BN6628_RS09745 phosphorylase: BN6628_RS09745 5'-deoxynucleotidase: BN6628_RS06305 ABC alpha subunit: 6 methylthiazol-5- D-glucopyranose long-chain fatty acid--CoA phosphotransferase: ptsP BN6628_RS15865 BN6628_RS18880 PAP phosphatase synthase BN6628_RS05720 NAD(P)H-hydrate riboflavin RS04750 disulfide synthase: protein] N - gondoate biosynthesis cytidine deaminase: BN6628_RS00110 a sugar a sugar thr thr BN6628_RS10805 ferroheme a BN6628_RS25355 yl)ethyl phosphate 6-phosphate ligase: BN6628_RS07225 phosphoenolpyruvate- FMN-dependent beta-N- BN6628_RS15470 beta-N- BN6628_RS18830 acyl-CoA nucleoside triphosphate NrnA: subunit dehydratase/ kinase/FAD transporter reductase: NAD phosphorylation and dephosphorylation BN6628_RS06520 octanoyl-L-lysine a (2E)-oct- (anaerobic) BN6628_RS05255 2'-deoxyadenosine α-D- a cis-delta17-3-[+ 8 isozymes] inositol menaquinol-7 biosynthesis thiamine lipoyl glucose-6-phosphate -protein NADH-azoreductase: acetylhexosaminidase: a long-linear acetylhexosaminidase: thioesterase: pyrophosphohydrolase: BN6628_RS16355 beta: trpB NAD(P)H-hydrate synthetase: of a sugar trxB (R)-4'-phosphopantothenate thiamine 2-enoyl-[acp] glucopyranose D-glyceraldehyde hydroxyC36:1- monophosphatase: NADPH a 5,10- heptaprenyl diphosphate synthase: isomerase: thymidine (2Z)-5-chloro-4- AMP diphosphate (Z)-15-tetracosenoyl-CoA phosphotransferase: ptsP BN6628_RS18240 BN6628_RS01500 α-D-glucan BN6628_RS01500 2'-deoxyadenosine BN6628_RS04515 BN6628_RS25275 a nucleoside 5'- trp epimerase: ribF + diphosphokinase: 2'-deoxyuridine purine-nucleoside 1-phosphate 3-phosphate [acp] BN6628_RS03490 serine serine NAD methylenetetrahydrofolate biosynthesis octanoyl-[acyl- a malonyl-[acp] an oleoyl-[acp] hydroxyhex-2-enedioate an [HPr protein]- N,N'-dimethyl-p- an N-acetyl-β- N-acetyl-D- di-homo-γ- dIMP monophosphate BN6628_RS02670 FAD a sugar RS19815 a sugar RS04755 all-trans-heptaprenyl lipA BN6628_RS05780 pyrimidine- phosphorylase: π anthranilate an alcohol chitin thr thr BN6628_RS11435 a [lipoyl-carrier carrier-protein] (11Z)-3-oxo-icos- N -phospho- pyruvate phenylenediamine D-hexosamine glucosamine linolenate myo-inositol all-trans-decaprenyl a reduced diphosphate thiamine nucleoside deoD NADH (2E,6E)-farnesyl 6 menaquinol-9 biosynthesis reductase: L-histidine diphosphate biosynthesis adenosylcobalamin IPP protein]-N - 11-enoyl-[acp] F6P thioredoxin diphosphate diphosphate menaquinol-6 biosynthesis BN6628_RS03485 phosphorylase: purine-nucleoside [+ 3 isozymes] salvage from cobalamin alkaline NAD/NADP heptaprenyl lipoyl-L-lysine synthase: fabF a sugar RS03535 a sugar menaquinol-8 biosynthesis an (11Z)-3-oxo- 6-phosphofructokinase: pyrimidine- deoA phosphorylase: lys RS02485 lys IPP (2E,6E)-farnesyl demethylmenaquinol-7 phosphatase: transhydrogenase NAD kinase: diphosphate demethylmenaquinol-9 2'-deoxyinosine 2-maleylacetate an octanoyl-[acp] icos-11-enoyl-[acp] pfkA nucleoside deoD ditrans,octacis- 1-stearoyl- a long-chain an [RNA]-3'- a uridine 38- a (3R)-3- diphosphatedecaprenyl cob(I)alamin BN6628_RS11120 alpha subunit: BN6628_RS20265 synthase: demethylmenaquinol-6 demethylmenaquinone thymine 16-hydroxypalmitate linoleate glycerophosphoglycerol H O a cis-delta19-3- 3-oxoacyl-ACP phosphorylase: undecaprenyldiphospho- a palmitoyl-[acp] sn-glycerol a purine fatty acyl-CoA 2 ser ribonucleoside- 40 in tRNA Ins(2)P met hydroxypimeloyl- ATP:cob(I)alamin demethylmenaquinone demethylmenaquinol-8 BN6628_RS10805 demethylmenaquinone methyltransferase: β-D-fructose 1,6- [+ 3 isozymes] purine-nucleoside dGMP oxo-C38:1-[acp] diphosphate [+ 4 isozymes] all-trans-heptaprenylBN6628_RS10390 deoA acyl-CoA synthetase: acyl-CoA synthetase: 3-phosphate glycerophosphodiester ribonucleoside acyl-CoA 2',3'- RluA family [acp] methyl ester adenosyltransferase: methyltransferase: demethylmenaquinone methyltransferase: BN6628_RS10370 3-oxoacyl-[acyl- reductase: bisphosphate phosphorylase: N-acetyl-(N- 1-acyl-sn-glycerol- L-serine ammonia-lyase, 3-oxoacyl-ACP inositol bifunctional 3-hydroxyacyl-a sugar RS17950 a sugar glycine betaine glycine betaine synthase: diphosphate BN6628_RS13935 BN6628_RS13935 phosphodiesterase: purine-nucleoside thioesterase: cyclophosphate pseudouridine RS05200 BN6628_RS06265 BN6628_RS10370 methyltransferase: BN6628_RS10370 menaquinol-9 carrier-protein] BN6628_RS13555 deoD acetylglucosaminyl) 3-phosphate iron-sulfur-dependent, RNA 2',3'-cyclic reductase: monophosphatase: glutamate N- [acyl-carrier- gly gly BN6628_RS11965 γ BN6628_RS05080 phosphorylase: 5'-deoxynucleotidase: BN6628_RS04515 synthase: all-trans-decaprenyl adenosylcobalamin BN6628_RS10370 menaquinol-6 reductase: [+ 6 isozymes] 3-oxoadipate long-chain fatty acid--CoA long-chain fatty muramoyl-L-alanyl- -D- acyltransferase: subunit beta: sdaAB phosphodiesterase: BN6628_RS05720 BN6628_RS00110 acetyltransferase/ protein] + fructose [+ 3 isozymes] BN6628_RS10070 BN6628_RS18830 diphosphate menaquinol-7 menaquinol-8 NADP BN6628_RS16815 α ligase: BN6628_RS07225 acid--CoA ligase: isoglutaminyl-L-lysyl- [+ 2 isozymes] acyl-CoA BN6628_RS06020 a (3R,11Z)-3-hydroxy- bisphosphate 2-deoxy-α- 2-deoxy- -D- peptidoglycan BN6628_RS102951-stearoyl- L-serine ammonia-lyase, an [RNA]-3'-BN6628_RS04960 a cis-delta19-3-[+ 8 isozymes] inositol amino-acid dehydratase a sugar RS23035 a sugar β uracil BN6628_RS07225 (glycyl) -D-alanyl-D-alanine sn-glycerol [+ 3 isozymes] thioesterase: [+ 4 isozymes] 6 6 -ketodecanoyl- ribose 1-phosphate 5 di-trans,octa-cisglycosyltransferase: 2-palmitoyl- glycerol α-D-ribose- 38- hydroxyC38:1- monophosphatase: acetyltransferase a (2E)- FabZ: fabZ N -(D- N -(D- icos-11-enoyl-[acp] aldolase: D-ribose 1- AMP diphosphate 16-hydroxypalmitoyl-CoA a peptidoglycan acyl-carrier protein 3-phosphate a purine base iron-sulfur-dependent, ribunucleoside- a pseudouridine [acp] inosine 5'-phosphate -undecaprenylBN6628_RS07005 sn-glycerol 1-phosphate 2'-deoxyguanosine BN6628_RS18880 [acp] BN6628_RS03490 ArgJ: argJ enoylpimeloyl- fructosyl) FrlA fructosyl) 3-hydroxyacyl- BN6628_RS18090 phosphate phosphopentomutase: AMP diphosphate linoleoyl-CoA dimer (S. aureus) a long-chain subunit beta: sdaAB 2'-phosphate 40 in tRNA synthase: fabF degradation diphosphate 3-phosphate myo-inositol N-acetyl-L- [acp] methyl ester -L-lysine -L-lysine [acyl-carrier- fructose-1,6- phosphopentomutase: deoB fatty acid pyruvate methionine a sugar RS10890 a sugar a 3-oxodecanoyl- Nucleoside and Nucleotide Biosynthesis protein] bisphosphate deoB 2-deoxy-D-ribose [acp] dehydratase aldolase, predicted 2-deoxy-D-ribose 5-phosphate IMP 3-oxoacyl-ACP FabZ: fabZ class II: fba ditrans,octacis- 1-stearoyl- 5'-deoxy-5'- a (3R)-3- a (3R)-3- a (3R,5Z)-3- PEP-driven D-mannitol superpathway of purine nucleotides de novo biosynthesis II 5-phosphate 18-hydroxystearate a 2,3,4-saturated a 2,3,4-saturated 2- preuroporphyrinogen a 3-oxoicosanoyl- a 3-oxoglutaryl- a cis-delta21-3- a sugar RS18705 a sugar D-mannitol pyrimidine reductase: deoxyribose- IMP dehydrogenase: undecaprenyldiphospho- a stearoyl-[acp] sn-glycerol a purine 2'- fluoroadenosine hydroxyhexacosanoyl- hydroxydocosanoyl- hydroxydodec- transporter 1-phosphate UMP biosynthesis III superpathway of 5-aminoimidazole Aminoacyl-tRNA Charging a (2E,11Z)-icosa- fatty acyl-[acp] lysophosphatidate dGTP XTP [acp] [acp] methyl ester oxo-C40:1-[acp] ribonucleosides salvage I Amine and Polyamine Biosynthesis BN6628_RS05720 phosphate BN6628_RS00270 acyl-CoA synthetase: N-acetyl-(N- 3-phosphate deoxyribonucleoside purine-nucleoside uroporphyrinogen- 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP [acp] [acp] 5-enoyl-[acp] of D-mannitol ribonucleotide biosynthesis 2,11-dienoyl-[acp] triose-phosphate deoxyribose- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- dGTP purine-nucleoside XTP/dITP diphosphatase: 3-hydroxyacyl- 3-hydroxyacyl- 3-hydroxyacyl- PRPP [+ 8 isozymes] phosphate aldolase: deoC XMP BN6628_RS13935 acetylglucosaminyl) 3-phosphate 3-phosphate phosphorylase: III synthase: reductase: reductase: reductase: [acyl-carrier- [acyl-carrier- [acyl-carrier- cytidine (2E,11Z)-icosa- isomerase: triphosphohydrolase: phosphorylase: BN6628_RS06305 nitrite nitrite gln hydrogencarbonate PRPP tRNA charging spermidine biosynthesis III a (3R)-3- aldolase: long-chain fatty acid--CoA muramoyl-L-alanyl-γ- acyltransferase: acyltransferase: BN6628_RS10070 BN6628_RS12315 BN6628_RS05720 BN6628_RS05720 BN6628_RS05720 protein] protein] protein] predicted RS22450 L-asparagine putrescine 2,11-dienoyl- BN6628_RS01040D-glyceraldehyde BN6628_RS05550 BN6628_RS10070 nucleoside triphosphate formate formate amidophosphoribosyltransferase: hydroxydecanoyl- DHAP deoC bifunctional ligase: BN6628_RS07225 D-isoglutaminyl-N-(β- BN6628_RS10295 BN6628_RS10295 [+ 3 isozymes] uroporphyrinogen- [+ 8 isozymes] [+ 8 isozymes] [+ 8 isozymes] dehydratase dehydratase dehydratase ABC cytidine deaminase: amidophosphoribosyltransferase: arginine- biosynthesis III biosynthesis I [acp] reductase: 3-phosphate acetaldehyde D-glyceraldehyde 3-phosphate a 2,3,4-saturated 1-stearoyl-2- 2'-deoxyguanosine PPP α [+ 3 isozymes] 5-fluoro-5- pyrophosphohydrolase: a (3R)-3- a (3R)-3- a cis-delta21-3- a sugar a sugar BN6628_RS03670 carbamoyl- [acp] metallophosphatase/ D-asparaginyl)-L-lysyl-peptidoglycan i 2-deoxy- - III synthase: transporter BN6628_RS05255 BN6628_RS03670 -tRNA (tRNA-dependent) 1,2-diacyl-sn stearoyl-sn hydroxyicosanoyl- hydroxyglutaryl- hydroxyC40:1- FabZ: fabZ FabZ: fabZ FabZ: fabZ 5-phospho-β- phosphate synthase 5-phospho-β- arg SAM 3-hydroxyacyl- BN6628_RS03485 glyceraldehyde- D-glyceraldehyde 5'-nucleotidase: AMP diphosphate 18-hydroxystearoyl-CoA di-trans,octa-cisD-alanyl-D-alanineglycosyltransferase: acyl-carrier protein acyl-carrier protein D-ribose 1- a purine base deoxy-D-ribose adenine BN6628_RS22505 BN6628_RS25275 a (2E)-hexacos- a (2E)-docos- a (2E,5Z)-dodeca- of a sugar gly CMP ligase: a peptidoglycan -glycerol 3- -glycerol 3- [acp] [acp] methyl ester [acp] D-ribosylamine small subunit: superpathway of guanosine D-ribosylamine arg [acyl-carrier- 3-phosphate acetaldehyde BN6628_RS19015 -undecaprenyl BN6628_RS07005 phosphate 1-phosphate XMP 2-enoyl-[acp] 2-enoyl-[acp] 3,5-dienoyl-[acp] uridine argS asp a gondoyl-[acp] 3-phosphate dimer (E. faeciums) phosphate phosphate uroporphyrinogen-III BN6628_RS08335 nucleotides de novo biosynthesis I phosphoribosylamine- adenosylmethionine protein] dehydrogenase: diphosphate a sugar RS18345 a sugar uridine kinase: arginine-- decarboxylase: phosphoribosylamine- carbamoyl- -glycine ligase: arg dehydratase gap acetyl-CoA guanosine nucleotides xanthosine BN6628_RS01575 tRNA ligase: BN6628_RS06010 -glycine ligase: phosphate synthase BN6628_RS03695 an L-aspartyl- agmatine FabZ: fabZ degradation III IMP BN6628_RS00640 an L-arginyl- agmatine 13-DPG 2-phospho-4-(cytidine 5'- a single 5'-chloro-5'- an apo-[LYS2 L- D-firefly 1-cis- a (3R)-3- a (3R,7Z)-3- a (3R,7Z)-3- BN6628_RS03695 large subunit: UMP [tRNA Asn ] adenosylmethionine a (2E)-dec- 18-hydroxyoleate a CDP- sn-glycerol a peptide with a H O a 3-oxopimeloyl- a cis-delta13-3- Arg acetyl-CoA purine-nucleoside diphospho)-2-C-methyl-D-erythritol 2-aminoadipyl- coenzyme A 2 vaccenoylglycerol- hydroxytetracosanoyl- hydroxytetradec- hydroxy-hexadec- a sugar RS07540 a sugar BN6628_RS08340 GAR [tRNA ] decarboxylase: agmatinase: diacylglycerol 3-phosphate hypoxanthine PRPP stranded DNA leader sequence deoxyadenosine luciferyl-CoA [acp] methyl ester oxo-C32:1-[acp] a tRNA Arg Asp-tRNA(Asn) 2-enoyl-[acp] 3-phosphoglycerate phosphorylase: acyl-CoA synthetase: 2-C-methyl-D- endonuclease IV: purine-nucleoside carrier-protein] acyl-CoA 3-phosphate [acp] 7-enoyl-[acp] 7-enoyl-[acp] IMP dehydrogenase: BN6628_RS06465 speB GMP CDP-diacylglycerol-- xanthine signal holo-[acyl- 1-acyl-sn-glycerol- 3-oxoacyl-ACP 3-oxoacyl-ACP 3-hydroxyacyl- 3-hydroxyacyl- 3-hydroxyacyl- GAR phosphoribosylglycinamide /Glu-tRNA(Gln) decanoyl-[acyl- kinase: BN6628_RS10070 BN6628_RS13935 erythritol 2,4- BN6628_RS11315 phosphorylase: thioesterase: asp carbamoyl BN6628_RS00270 agmatinase: bifunctional glycerol-3-phosphate 3- phosphoribosyltransferase: peptidase I: lepB carrier- 3-phosphate reductase: reductase: [acyl-carrier- [acyl-carrier- [acyl-carrier- formyltransferase: amidotransferase dAdoMet carrier-protein] BN6628_RS24075 [+ 3 isozymes] long-chain fatty acid--CoA cyclodiphosphate deoxyribonuclease BN6628_RS10070 BN6628_RS18880 phosphate speB metallophosphatase/ phosphatidyltransferase: BN6628_RS17515 signal protein] acyltransferase: BN6628_RS05720 BN6628_RS05720 protein] protein] protein] a sugar RS04270 a sugar BN6628_RS03685 subunit GatB: reductase: ligase: BN6628_RS07225 synthase: IV: BN6628_RS05755 [+ 3 isozymes] acyl-CoA phosphoglycerate superpathway of pyrimidine 5'-nucleotidase: xanthine 1-(3-sn- pgsA peptidase I: lepB synthase: 1-cis-vaccenoyl-BN6628_RS10295 a (3R)-3-[+ 8 isozymes] a cis-delta13-3-[+ 8 isozymes] dehydratase dehydratase dehydratase aspartate BN6628_RS20550 polyamine putrescine BN6628_RS03485 biotin-carboxyl carrier protein assembly [+ 2 isozymes] BN6628_RS21675 5-chloro-5- thioesterase: XMP FGAR cysteine-- kinase: pgk ribonucleosides degradation BN6628_RS19015 phosphatidyl) a 5'-phosphooligonucleotide a leader sequence a peptide a holo-[LYS2 L- acpS 2-palmitoleoyl hydroxypimeloyl- hydroxyC32:1- FabZ: fabZ FabZ: fabZ a (2E,7Z)-FabZ: fabZ carbamoyltransferase cys aminopropyltransferase: AMP diphosphate 18-hydroxyoleoyl-CoA CMP IMP 2-C-methyl-D-erythritol- adenine deoxyribose ∆ 3 ∆ 7 tRNA ligase: [+ 2 isozymes] guanosine CMP BN6628_RS04515 phosphatidate [acp] methyl ester a (2E)-tetracos- a trans- -cis- - FGAR catalytic subunit: a [biotin carboxyl- 3-phospho-D-glycerate -sn-glycerol 1-phosphate 2-aminoadipyl- 3',5'-ADP [acp] hexadeca-2,7- predicted xanthosine-5'- phosphoribosylformylglycinamidine BN6628_RS21655 BN6628_RS00615 a decanoyl-[acp] cytidine 2,4-cyclodiphosphate D-firefly luciferin 2-enoyl-[acp] tetradecenoyl-[acp] BN6628_RS08325 an L-cysteinyl- an L-asparaginyl- carrier protein]-L-lysine cytidine deaminase: 3-phosphate carrier-protein] dienoyl-[acp] ABC phosphoribosylformylglycinamidine phosphate:L- synthase subunit PurS: Cys [tRNA Asn ] S-methyl-5'- N 1 -(3-aminopropyl) purine-nucleoside a sugar a sugar [tRNA ] 3-oxoacyl-[acyl- biotin--[acetyl-CoA- 2,3- BN6628_RS05255 transporter N-carbamoyl- glutamine amido- BN6628_RS03655 Cys phosphorylase: deoD urate synthase subunit PurS: a tRNA aminoacyl-tRNA thioadenosine agmatine diphosphoglycerate- NADH repair uridine L-aspartate ligase (AMP-forming) carrier-protein] carboxylase] ligase: [+ 3 isozymes] (R)-4'- RNase III mRNA a 1-alkyl-sn of a sugar BN6628_RS03655 [+ 2 isozymes] 1 dependent a (1->4)- a (7Z)-3-oxo- a (3R)-3- a (3R,5Z)-3- hydrolase: N -aminopropylagmatine reductase: BN6628_RS10600 pyrimidine-nucleoside 7-hydroxylaurate propanoyl-CoA H O a carboxylic ester [EntB aryl- 5-aminolevulinate 1-myristoylglycerol [+ 2 isozymes] : BN6628_RS03590 phosphoglycerate phosphopantothenoyl- processing a purine 2 α-D-glucan coenzyme A hexadec-7- -glycerol 3- hydroxyicosanoyl- hydroxy-tetradec- dihydroorotase: FGAM BN6628_RS25250 ureohydrolase: speB BN6628_RS16815 a [biotin carboxyl-carrier NADH phosphorylase: deoA guanine arsenate glycogen/starch/ carrier protein] 3-phosphate GTP a sugar RS09570 a sugar mutase: gpmA acyl-CoA synthetase: L-cysteine substrateribonuclease III: ribonucleoside acyl-CoA thioesterase: carboxylic ester holo-[acyl- porphobilinogen 1-acyl-sn-glycerol- enoyl-[acp]3-oxoacyl-ACP phosphate1-acyl-sn-glycerol- [acp] 3-hydroxyacyl- 5-enoyl-[acp]3-hydroxyacyl- BN6628_RS08330 β 6 bifunctional purine-nucleoside FGAM GMP -ketododecanoyl- protein]-N -biotinyl-L-lysine uracil BN6628_RS13935 BN6628_RS04515 alpha-glucan hydrolase: synthase: 3-phosphate adenylate/guanylate phosphoribosylformylglycinamidine glutamine--tRNA asn spermidine phosphopantothenoylcysteine BN6628_RS16800 phosphorylase: carrier- reductase: 3-phosphate [acyl-carrier- [acyl-carrier- superpathway of adenosine [acp] 2-phospho-D-glycerate long-chain fatty acid--CoA acyl-CoA thioesterase: phosphorylase: BN6628_RS03035 BN6628_RS06495 acyltransferase: cyclase domain- (S)-dihydroorotate cyclo-ligase: BN6628_RS03680 ligase/YqeY domain decarboxylase/ ribonuclease III: BN6628_RS10070 protein] BN6628_RS13555 acyltransferase: protein] protein] phosphoribosylformylglycinamidine nucleotides de novo biosynthesis I gln synthase: fabF ligase: BN6628_RS07225 BN6628_RS18880 BN6628_RS15470 containing protein: predicted fusion protein: phosphopantothenate-- BN6628_RS21650 α-D- carboxylesterase: synthase: delta-aminolevulinic 1-myristoyl-2-BN6628_RS10295 a (3R,7Z)-3-[+ 6 isozymes] a 2-acyl-1-alkyl-BN6628_RS10295 dehydratase dehydratase cyclo-ligase: BN6628_RS03680 guanylate kinase: a 3- phosphopyruvate RNase III [+ 3 isozymes] a (1->4)- AIR BN6628_RS22425 a [biotin carboxyl- propanoate BN6628_RS04730 acpS acid dehydratase: BN6628_RS19945 FabZ: fabZ FabZ: fabZ ABC dihydroorotate BN6628_RS09370 an L-glutaminyl- oxododecanoyl- hydratase: (R)-NADHX AMP diphosphate 7-hydroxylauroyl-CoA cysteine ligase CoaBC: coaBC an mRNA fragment processing glucopyranose α palmitoleoyl hydroxy-hexadec- sn-glycerol cyclic-GMP a (2E,5Z)- a sugar a sugar Gln ribose-1-arsenate a purine base -D-glucan a holo-[EntB aryl- BN6628_RS04360 a (2E)-icos- transporter AIR dehydrogenase asp IMP [tRNA ] [acp] carrier-protein dimer]- BN6628_RS01050 bifunctional 5,6-dihydrouracil xanthine 4'-phosphopantetheine product mRNA 1-phosphate a carboxylate an alcohol 3',5'-ADP phosphatidate 7-enoyl-[acp] 3-phosphate tetradeca-2,5- Gln gln 6 carrier protein] 2-enoyl-[acp] of a sugar electron a tRNA glutaminyl-tRNA 3-oxoacyl-ACP N -biotinyl-L-lysine ADP-dependent porphobilinogen dienoyl-[acp] GDP 5-(carboxyamino) transfer subunit: biosynthesis via reductase: acetyl-CoA phosphoenolpyruvate NAD(P)H-hydrate hydantoinase subunit adenylosuccinate a sugar RS11055 a sugar imidazole BN6628_RS11580 transamidation BN6628_RS05720 carboxylase dehydratase/ beta: BN6628_RS12700 synthase: biotin carboxylase: ribonucleotide PRPP superpathway of pyrimidine biotin carboxylase pyruvate 1-stearoyl- a 3,5,7,9,11,13,15- 4-(cytidine 5'- 1-cis- a (3R,5Z)-3- 1498 a (5Z)-3- a (3R)-3- a (3R,6Z)-3- [+ 8 isozymes] NAD(P)H-hydrate α a [DNA]-3'- a 5'-phospho- + α a uracil synthase: orotate BN6628_RS24885 Glu BN6628_RS13020 kinase: pyk 3-ureidopropanoate urate purine ribonucleosides degradation α-linolenate adenosylcobinamide- -ribazole NAD palmitoyl-CoA H O -D- [EntF L-seryl- nucleoside- ribonucleoside- nucleobases salvage a (3R)-3- subunit: accC epimerase: an oleoyl-[acp] sn-glycerol hydroxyl [DNA] 2 hepta-oxo- coenzyme A diphospho)-2-C- vaccenoylglycerol- hydroxy-tetradec- in 16S rRNA oxododec- hydroxyglutaryl- hydroxyoctadec- Glu [+ 2 isozymes] GDP 5'-phosphate glucopyranose ATP carrier protein] BN6628_RS03640 diphosphate kinase: diphosphate hydroxydodecanoyl- biotin carboxylase: BN6628_RS02670 long-chain fatty acid--CoA adenosylcobinamide- 3-phosphate DNA ligase: acyl-CoA thioesterase: hexadecanoyl-[PKS-acp] methyl-D-erythritol4-(cytidine 5'- 3-phosphate1-acyl-sn-glycerol- 5-enoyl-[acp]3-oxoacyl-ACP 16S rRNA 5-enoyl-[acp]3-oxoacyl-ACP [acp] methyl ester 6-enoyl-[acp] a sugar RS17245 a sugar orotate adenylo-succinate uracil pyruvate (S)-NADHX 1-acyl-sn-glycerol- aldo/keto reductase: 1-phosphate holo-[acyl- 3-hydroxyacyl- 3-hydroxyacyl- BN6628_RS17985 reductase [acp] BN6628_RS13020 ligase: BN6628_RS07225 GDP BN6628_RS14885 BN6628_RS04515 glucose-1-phosphate diphospho)- 3-phosphate reductase: (uracil(1498)-N(3))- reductase: N5-CAIR phosphoribosyltransferase: bifunctional pyr operon an L-glutamyl- an L-glutamyl- adenosine 3-phosphate BN6628_RS11985 carrier- [acyl-carrier- [acyl-carrier- nucleoside- subunit alpha: adenylosuccinate Glu 3-hydroxyacyl- a [carboxyl-carrier acyl-CoA synthetase: ribazoletransferase: DNA ligase: acyl-CoA thioesterase: adenylyltransferase: 2-C-methyl-D- acyltransferase: BN6628_RS13555 methyltransferase: BN6628_RS13555 BN6628_RS08350 transcriptional regulator/uracil [tRNA ] Gln ATP-dependent acyltransferase: protein] protein] protein] [tRNA ] 6 [+ 12 isozymes] diphosphate kinase: BN6628_RS02705 lyase: glu [acyl-carrier- protein dimer]-N - BN6628_RS13935 cobS BN6628_RS05040 BN6628_RS18880 BN6628_RS11525 3 BN6628_RS07845 5-(carboxyamino) phosphoribosyltransferase a tRNA NADH-hydrate β-alanine BN6628_RS102951-stearoyl-2- 9-hydroxy-3,5,7,11,13,15- synthase: erythritol kinase: 1,2-dicis-BN6628_RS10295 a (5Z)-3-oxo-[+ 6 isozymes] an N - a (3R,5Z)-3-[+ 6 isozymes] dehydratase dehydratase a sugar RS22860 a sugar BN6628_RS10395 [+ 2 isozymes] BN6628_RS03645 Asp-tRNA(Asn) protein] carboxybiotinyl-L-lysine palmitate [+ 2 isozymes] BN6628_RS25220 1498 imidazole PyrR: BN6628_RS08320 dehydratase: α adenosylcobalamin acyl-carrier protein oleoyl-sn-glycerol hexaoxohexadecanoyl- a holoacpS-[EntF 2-phospho-4-(cytidine vaccenoyl- tetradec-5- methyluracil hydroxydodec- a (2E)- FabZ: fabZ a (2E,6Z)-FabZ: fabZ orotidine 5'- /Glu-tRNA(Gln) dehydratase AMP diphosphate -linolenoyl-CoA GMP NMN AMP [DNA] ADP-α-D-glucose ribonucleotide uracil BN6628_RS02670 5'-phosphate 3-phosphate [PKS-acp] 3',5'-ADP L-seryl-carrier 5'-diphospho)-2-C- phosphatidate enoyl-[acp] in 16S rRNA 5-enoyl-[acp] enoylglutaryl- octadecadienoyl- phosphate amidotransferase FabZ: fabZ mutase: purE AMP phosphoribosyltransferase: protein] methyl-D-erythritol [acp] methyl ester [acp] subunit GatB: NADH a sugar RS01305 a sugar orotidine-5'- GTP dGDP BN6628_RS22285 a (2E)-dodec- CAIR isoleucine-- BN6628_RS20550 xanthosine adenosine inosine guanosine phosphate UMP ile 2-enoyl-[acp] adenylate kinase: tRNA ligase: phosphatidylcholine 6-methoxy-2-all- an organic a (9Z)-3- a (9Z)-3- a (3R,9Z)-3- decarboxylase: nucleoside- [+ 2 isozymes] pristanate 1-myristoylglycerol an acyl-[acyl- a nucleoside maltotetraose a [release factor]- 1-palmitoylglycerol L,L- phosphoribosylaminoimidazolesuccinocarboxamide BN6628_RS21450 (d)CMP kinase: BN6628_RS08290 an L-isoleucyl- dodecanoyl-[acyl- biosynthesis V UTP and CTP dephosphorylation I a palmitoleoyl-[acp] a malonyl-[acp] a ribonucleic acid trans-octaprenyl- hydroperoxide oxohexadec- oxooctacos- hydroxyhexadec- pyrF diphosphate kinase: an L-glutaminyl- 3-phosphate carrier protein] triphosphate GTP H O L-glutamine 3-phosphate diaminopimelate IMP predicted synthase: BN6628_RS03650 BN6628_RS10290 [tRNA Ile ] carrier-protein] purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside acyl-CoA synthetase: glycogen/starch/ 1,4-benzoquinone 2 alkyl hydroperoxide peptide chain 1-acyl-sn-glycerol- 9-enoyl-[acp] 9-enoyl-[acp] 9-enoyl-[acp] Gln an L-1- 1-acyl-sn-glycerol- 3-oxoacyl-[acyl- DNA-directed 3-oxoacyl-ACP 3-oxoacyl-ACP 3-hydroxyacyl- BN6628_RS17985 Ile [tRNA ] demethylmenaquinone GTPase ObgE: diaminopimelate bifunctional ABC UMP [+ 2 isozymes] a tRNA reductase: UTP phosphorylase: phosphorylase: phosphorylase: phosphorylase: BN6628_RS13935 3-phosphate carrier-protein] RNA polymerase alpha-glucan reductase: release factor 3-phosphate reductase: reductase: [acyl-carrier- a sugar a sugar SAICAR nucleoside- ADP phosphatidylethanolamine Respiration methyltransferase: BN6628_RS06620 epimerase: metallophosphatase/ transporter BN6628_RS03485 BN6628_RS10070 deoD deoD deoD long-chain fatty acid--CoA acyltransferase: reductase: subunit omega: phosphorylase: BN6628_RS10215 N(5)-glutamine acyltransferase: BN6628_RS05720 BN6628_RS05720 protein] diphosphate kinase: UDP Carbohydrate Biosynthesis BN6628_RS15470 BN6628_RS10370 [+ 4 isozymes] BN6628_RS09350 5'-nucleotidase: of a sugar CTP synthase: [+ 3 isozymes] [+ 3 isozymes] [+ 3 isozymes] [+ 3 isozymes] ligase: BN6628_RS07225 BN6628_RS10295 BN6628_RS16815 BN6628_RS09375 3-methyl-6-methoxy- alkylhydroperoxidase: methyltransferase: 1-palmitoyl-2-BN6628_RS10295 [+ 8 isozymes] [+ 8 isozymes] dehydratase adenylosuccinate BN6628_RS10395 a phosphatidyl-N- 1-myristoyl-2- α-D-glucopyranose + a (3R,9Z)-3- a cis-delta9-3- BN6628_RS19015 nucleoside-diphosphate a dodecanoyl-[acp] 2-oxoisovalerate decarboxylation to isobutanoyl-CoA BN6628_RS00660 maltotriose 2-octaprenyl-1,4- phosphate GDP H BN6628_RS24625 prmC meso- FabZ: fabZ lyase: acyl-carrier protein palmitoleoyl acyl-carrier protein a 3-oxoacyl-[acp] [+ 8 isozymes] 5 palmitoleoyl hydroxyhexadec- hydroxyC28:1- a (2E,9Z)- adenine and F0F1 ATP synthase ribonucleoside- kinase: BN6628_RS17985 UDP-N-acetyl-D- methylethanolamine α-D-ribose- AMP diphosphate pristanoyl-CoA 1-phosphate a [release factor]-N diaminopimelate inosine a sugar RS11850 a sugar BN6628_RS03645 PRPP biosynthesis I α an [apo BCAA UMP phosphatidate a ribonucleic acid benzoquinone an alcohol phosphatidate 9-enoyl-[acp] [acp] hexadeca-2,9- adenosine salvage I dGTP subunit epsilon: diphosphate nucleoside-diphosphate leu glucosamine biosynthesis I dTDP-L-rhamnose UDP- -D- phospholipid CTP 1-phosphate -methyl-L-glutamine leucine--tRNA ligase: dehydrogenase dienoyl-[acp] AICAR BN6628_RS22230 reductase kinase: BN6628_RS10395 biosynthesis I galactose 3-oxoacyl-[acyl- methyltransferase: 2-oxoisovalerate bifunctional thymine degradation BN6628_RS07710 an L-leucyl- D-glucopyranose D-ribose 5- E2 protein] N 6 phosphopentomutase: [+ 7 isozymes] subunit alpha: α-D-glucopyranose biosynthesis carrier-protein] BN6628_RS04290 dehydrogenase: metallophosphatase/ nitrate RS13250 nitrate UTP [tRNA Leu ] 6-phosphate phosphate deoB bifunctional adenosine ribose-phosphate UDP-α-D-glucose reductase: -lipoyl-L-lysine 5'-nucleotidase: 967 a 3- a (9Z)-3-oxo- a 1-acyl-sn BN6628_RS02705 Leu glucose-6-phosphate 1-phosphate a phosphatidyl-N- BN6628_RS10010 thymine decaprenyl- D-arabinofuranose a cytosine 1-palmitoylglycerol a [protein]-L- a (3R,9Z)-3- purine-nucleoside a tRNA BN6628_RS16815 laurate CMP D-ribose 5- phytenate 1-palmitoylglycerol 1-myristoylglycerol an unsulfurated a RNA-DNA hybrid phosphoribosylaminoimidazolecarboxamide [+ 2 isozymes] CTP synthase: isomerase: glucose-1-phosphate pyrophosphokinase: UDP-glucose dimethylethanolamine branched-chain BN6628_RS19015 a palmitoleoyl-[acp] a myristoyl-[acp] pyrophosphoryl-(N cys 5-phosphate in 16S rRNA oxodocosanoyl- 3-phosphate octadec-9- β-isoaspartate ATP -glycerol 3- hydroxy-octadec- phosphorylase: deoD β 2-oxoisovalerate phosphate 3-phosphate 3-phosphate [sulfur carrier] formyltransferase/IMP cyclohydrolase ATP BN6628_RS00660 BN6628_RS05780 thymidylyltransferase: BN6628_RS25240 4-epimerase -ketomeristoyl- acyl-CoA phospholipid alpha-keto acid bifunctional uridine long-chain fatty acid--CoA 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- -acetylglucosamine) cysteine desulfurase: 2-dehydro-3- ribonuclease HII: 16S rRNA [acp] 3-oxoacyl-ACP 1-acyl-sn-glycerol- enoyl-[acp]3-oxoacyl-ACP protein-L- phosphate1-acyl-sn-glycerol- 9-enoyl-[acp]3-hydroxyacyl- dehydrogenase: 5,6-dihydrothymine Ca 2+ Cax Ca 2+ PurH: BN6628_RS03690 [+ 3 isozymes] pyrimidine deoxyribonucleotides CTP F6P rfbA ribose-phosphate GalE: galE [acp] synthetase: methyltransferase: ligase: BN6628_RS07225 -N-acetylmuramyl- BN6628_RS24995 deoxyphosphooctonate BN6628_RS16700 (cytosine(967)-C(5) reductase: 3-phosphate reductase: isoaspartate O- adenylate/guanylate 3-phosphate dTDP-α-D-glucose α BN6628_RS10010 dehydrogenase metallophosphatase/ pyrimidine deoxyribonucleotides 3-phosphate 3-phosphate peptidoglycan [acyl-carrier- adenine de novo biosynthesis I pyrophosphokinase: UDP- -D-galactose synthase: fabF acyl-CoA synthetase: aldolase: )-methyltransferase methyltransferase: cyclase domain- FAICAR dADP BN6628_RS13935 BN6628_RS04290 subunit E2: 5'-nucleotidase: hydantoinase dephosphorylation acyltransferase: acyltransferase: (pentapeptide)glycosyltransferase: [+ 3 isozymes] ribonuclease H: BN6628_RS05720 acyltransferase: BN6628_RS13555 acyltransferase: protein] glutamine-- dTDP-glucose 4,6- BN6628_RS00890 [+ 2 isozymes] BN6628_RS13935 ω, mono- a sulfurated BN6628_RS14925 RsmB: BN6628_RS14400 containing protein: UDP CTP val long-chain fatty BN6628_RS22700 BN6628_RS19015 subunit beta: nucleoside triphosphate BN6628_RS102951-palmitoyl-2- BN6628_RS10295 a peptidoglycanBN6628_RS07005 ala BN6628_RS01750 a (3R)-3-[+ 8 isozymes] 1-palmitoyl-BN6628_RS10295 a (3R,9Z)-3-[+ 6 isozymes] a protein L-β- a 1-acyl-2-BN6628_RS10295 dehydratase adenine valine--tRNA ligase: fructose-6- dehydratase: rfbB PRPP a phosphatidylcholine BN6628_RS12700 dimyristoyl trans,octa-cis [sulfur carrier] a nucleoside 5'- BN6628_RS09400 BN6628_RS19945 Co 2+ Co 2+ bifunctional nucleoside- a 3-oxotetradecanoyl- acid--CoA ligase: pyrophosphohydrolase: KDO-8P DNA 967 2-myristoyl isoaspartate palmitoyl-sn FabZ: fabZ CorA phosphoribosyltransferase: ribonucleoside- phosphate an [apo BCAA an [apo BCAA dehydrogenase cytidine acyl-carrier protein palmitoleoyl acyl-carrier protein dimer a 5-methylcytosine hydroxydocosanoyl- hydroxy-octadec- a (2E,9Z)- 2+ 2+ BN6628_RS06515 an L-valyl- dTDP-4-dehydro-6- diphosphate AMP phytenoyl-CoA phosphatidate -decaprenyl monophosphate α cyclic-AMP Mg Mg phosphoribosylaminoimidazolecarboxamide diphosphate diphosphate kinase: [acp] BN6628_RS07225 6 3-(carbamoylamino)- BN6628_RS25275 phosphatidate (mycobacteria) [acp] phosphatidate 9-enoyl-[acp] -methyl ester -glycerol 3- octadeca-2,9- BN6628_RS06840 [tRNA Val ] transaminase deoxy-α-D-glucopyranose dehydrogenase E2 protein] N -S-[2- dCTP dCMP diphosphate in 16S rRNA formyltransferase/IMP cyclohydrolase CDP BN6628_RS17985 6 phosphate reductase Val (isomerizing) 3-oxoacyl-ACP E2 protein] N - methylpropanoyl]dihydrolipoyl- 2-methylpropanoate dienoyl-[acp] PurH: BN6628_RS03690 a tRNA dTDP-4- lauroyl-CoA AMP subunit alpha: ribonucleoside- nucleoside- : glmS reductase: dihydrolipoyl-L-lysine L-lysine S-methyl-5'-thioadenosine Co 2+ Co 2+ dehydrorhamnose CorA BN6628_RS02705 diphosphate kinase: deoxyuridine Detoxification 2+ 2+ diphosphate D-glucosamine 3,5-epimerase: rfbC BN6628_RS05720 degradation IV 1-cis- peptidoglycan peptidoglycan 1-deoxy-L- a 3- a (7Z)-3- 3-carboxy- (S)-1-pyrroline- a (3R,11Z)-3- Mg Mg IMP [+ 2 isozymes] reductase BN6628_RS10395 5'-triphosphate decanoate 1-palmitoylglycerol an N-modified a 3-oxohexacosanoyl- 1-palmitoylglycerol MEP 6-phosphate dTDP-4-dehydro- [+ 8 isozymes] S-methyl-5'- a palmitoleoyl-[acp] vaccenoylglycerol- a myristoyl-[acp] tetrapeptide, tetrapeptide, ATP H O ARP glycero-tetrulose oxodocosanoyl- 3-phosphate oxohexacos- 2,5-dihydro- 5-carboxylate hydroxyoctadec- dUDP long-chain fatty (R)-3-amino-2- nucleotidohydrolase: 3-phosphate aminoacyl-[tRNA] 2 [acp] subunit alpha: phosphoglucosamine β-L-rhamnose a (3R)-3- thioadenosine reactive oxygen species degradation acyl-CoA synthetase: 3-phosphate glycan chain 1 glycanL,D-transpeptidase: chain 2 aminoacyl-tRNA 4-phosphate 3-oxoacyl-ACP [acp] 3-oxoacyl-ACP 1-acyl-sn-glycerol- 7-enoyl-[acp]3-oxoacyl-ACP 5-oxofuran- 1-deoxy-D-xylulose- L-glutamate 11-enoyl-[acp] acid activation 5'-methylthioadenosine/ methylpropanoate BN6628_RS08675 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- ATPase: 6,7-dimethyl-8- 3-hydroxyacyl- BN6628_RS02705 dATP ala hydroxytetradecanoyl- 2-oxoisovalerate BN6628_RS13935 3-phosphate 2-acetate 5-phosphate gamma- 2+ 2+ nucleoside- CMP phosphorylation alanine--tRNA ligase: mutase: dTDP-4- 3-phosphate 3-phosphate BN6628_RS17025 hydrolase: BN6628_RS09505 ribityllumazine reductase: reductase: reductase: 3-carboxymuconate [acyl-carrier- Mg RS01520 Mg [+ 2 isozymes] [acp] stearate biosynthesis a long-chain dehydrogenase: adenosylhomocysteine [+ 2 isozymes] long-chain fatty acid--CoA acyltransferase: reductoisomerase: semialdehyde diphosphate kinase: BN6628_RS06960 an L-alanyl- BN6628_RS21270 dehydrorhamnose dUTP dUMP superoxide acyltransferase: acyltransferase: L,D-transpeptidase: BN6628_RS25250 synthase: BN6628_RS05720 BN6628_RS05720 BN6628_RS05720 cyclase: protein] 3-hydroxyacyl- II (bacteria and plants) fatty acid BN6628_RS10010 nucleosidase: ligase: BN6628_RS07225 an N-modified an uncharged [+ 6 isozymes] BN6628_RS10295 BN6628_RS16405 dehydrogenase: IMP dehydrogenase: BN6628_RS17985 dCDP CMP Ala D-glucosamine reductase: rfbD long-chain fatty BN6628_RS102951-cis-vaccenoyl- BN6628_RS102951-palmitoyl- peptidoglycanBN6628_RS17570 BN6628_RS10170 a (3R)-3-[+ 8 isozymes] a (3R)-3-[+ 8 isozymes] 1-palmitoyl-2- a (3R,7Z)-3-[+ 8 isozymes] BN6628_RS16985 1-deoxy-D- dehydratase [tRNA ] [acyl-carrier- BN6628_RS09220 superoxide dismutase: tRNA H + phosphate ADP pruA (d)CMP kinase: Ala 1-phosphate amino acid 6,7-dimethyl-8-(1- 3-carboxy-cis BN6628_RS00270 nucleoside- a tRNA acid--CoA ligase: branched-chain acyl-carrier protein 2-palmitoleoyl acyl-carrier protein 2-myristoyl D-ala DAP-DAP hydroxyhexacosanoyl- hydroxydocosanoyl- cis-vaccenoyl hydroxyhexacos- xylulose 5- FabZ: fabZ 2+ 2+ nucleoside- dTDP-β-L-rhamnose protein] MTR BN6628_RS03385 diphosphate AMP decanoyl-CoA D-ribityl)lumazine a (2E,11Z)- Mg RS20665 Mg diphosphate kinase: BN6628_RS10290 bifunctional UDP-N- a palmitoyl-[acp] BN6628_RS07225 alpha-keto acid 5-hydroxy-CTP 5-hydroxy-CMP phosphatidate phosphatidate crosslink [acp] [acp] phosphatidate 7-enoyl-[acp] ,cis-muconate phosphate Glu diphosphate kinase: dehydratase superoxide dismutase: octadeca-2,11- asp BN6628_RS10395 CDP acetylglucosamine 3-oxo- dehydrogenase BN6628_RS17985 FabZ: fabZ acyl-CoA BN6628_RS03420 dienoyl-[acp] nucleoside-diphosphate diphosphorylase/ stearoyl-[acp] synthetase: subunit E2: dUTP nucleoside- a (2E)-tetradec- synthase: fabF a reduced kinase: BN6628_RS17985 glucosamine-1- fructan biosynthesis a 3-oxooctadecanoyl- BN6628_RS13935 BN6628_RS22700 hydrogen peroxide XMP adenylosuccinate diphosphate kinase: asparagine-- a long-chain a (2'R)-2'- a [protein]- 1402 966 a (7Z)-3- (5Z)- a 1-acyl-sn an oxidized H O c-type deoxyuridine asn phosphate N- 2-enoyl-[acp] a 1-phosphatidyl- 1-palmitoylglycerol FAD a [protein]- a 3-oxotetracosanoyl- a cytidine a guanine roseoflavin 2 synthase: BN6628_RS10395 nucleoside-diphosphate tRNA ligase: [acp] octanoate hydroxy- a palmitoyl-[acp] glycerophosphoserine a [protein]-L-lysine H O diphosphate oxotetradec- -glycerol 3- nitroaromatic cytochrome 5'-triphosphate acetyltransferase fatty acyl-CoA 1D-myo-inositol 3-phosphate L-glutamine 2 L-threonine [acp] in 16S rRNA in 16S rRNA dodecenoyl-CoA RS02950 an oxidized BN6628_RS24885 kinase: BN6628_RS10395 BN6628_RS10665 an L-asparaginyl- sucrose myristoyl-[acyl- 3-oxoacyl-ACP acyl-CoA synthetase: phytoceramide glycerophosphodiester transglutaminase: FAD:protein FMN 16S rRNA 16S rRNA 7-enoyl-[acp] acyl-CoA phosphate compound bifunctional xanthosine-5'- nucleotidohydrolase: dCTP GlmU: glmU catalase: inositol 1-acyl-sn-glycerol- manganese- 3-oxoacyl-ACP 3-oxoacyl-ACP 1-acyl-sn-glycerol- O c-type Asn carrier-protein] BN6628_RS13935 BN6628_RS11880 transferase: dehydrogenase: NAD(P)H riboflavin 2 phosphate:L- BN6628_RS08675 CTP [tRNA ] reductase: Macromolecule Modification L-serine Amino Acid Degradation BN6628_RS14575 phosphorylceramide 3-phosphate phosphodiesterase: dependent inorganic reductase: (cytidine(1402)-2'-O) (guanine(966)-N(2) reductase: 3-phosphate cytochromea reduced Asn N-acetyl-α-D- reductase: L-asparagine nitroreductase: glutamine amido- adenylo-succinate tRNA levansucrase: BN6628_RS05720 degradation L-proline degradation [+ 2 isozymes] long-chain fatty acid--CoA synthase: acyltransferase: BN6628_RS17790 a protein with[+ an 2 isozymes] pyrophosphatase: BN6628_RS16010 BN6628_RS05720 -methyltransferase: )-methyltransferase BN6628_RS13555 BN6628_RS07220 acyltransferase: kinase/FAD H O c-type [+ 2 isozymes] glucosamine BN6628_RS03485 degradation I BN6628_RS17715 2 BN6628_RS24765 H O hydroxyl radical ligase: BN6628_RS07225 [+ 2 isozymes] 6 γ rsmI 2 RsmD: rsmD [+ 2 isozymes] synthetase: ligase (AMP-forming) [+ 8 isozymes] queuosine biosynthesis 2 a very-long-chainBN6628_RS06795 BN6628_RS10295 N -( -glutamyl)- BN6628_RS21060 a [protein]-FMN- a (3R)-3-[+ 8 isozymes] a 2'-O- an N - a (3R,7Z)-3-[+ 6 isozymes] a 1,2-diacyl-BN6628_RS10295 a reduced RS06210 cytochrome adenylosuccinate dUMP 1-phosphate a 1,2-diacyl- AMP (2E,5Z)- ribF an oxidized : BN6628_RS03590 superpathway of pyrimidine deoxyribonucleoside salvage levansucrase: a (3R)-3- acyl-CoA hydrolysis dipalmitoyl sn-glycerol L-lysine crosslink phosphate + L-threonine 1402 966 nitroaromatic 1-kestotriose a myristoyl-[acp] ser O inositol phospho-(2'R)- acyl-carrier protein ser H hydroxytetracosanoyl- methylcytidine methylguanine hydroxytetradec- dodecenoyl-CoA sn-glycerol O c-type lyase: bifunctional UDP-N- hydroxyoctadecanoyl- pro asn 2 diphosphate AMP octanoyl-CoA sn-glycerol phosphatidate 3-phosphate roseoflavin 2 thymidylate BN6628_RS24770 preQ L-serine 2'-hydroxyphytoceramide [acp] in 16S rRNA in 16S rRNA 7-enoyl-[acp] 3-phosphate compound a reducedcytochrome BN6628_RS03645 acetylglucosamine 0 proline asparaginase: 5'-phosphate GMP synthase: 2'-deoxycytidine aspartate-- 3-oxoacyl-[acyl- [acp] a 2,3,4-saturated H O c-type asp diphosphorylase/ levansucrase: 3-hydroxyacyl- NADPH-dependent ammonia- dehydrogenase: L-methionine BN6628_RS20645 2 BN6628_RS11470 tRNA ligase: 6-kestotriose carrier-protein] fatty acyl CoA CoxB cytochrome cytidine deaminase: glucosamine-1- BN6628_RS24765 [acyl-carrier- acyl-CoA 7-cyano-7- lyase, BN6628_RS18060 degradation II asparaginase: an oxidized AMP thymidylate BN6628_RS06895 reductase: (S)-1-pyrroline- 6 a 2'- guanylate kinase: an L-aspartyl- phosphate N- protein] thioesterase: deazaguanine iron-sulfur- BN6628_RS04200 DNA combined with exogenous DNA an O - a 5'-half-tRNA a cytidine 1402 a (5Z)-3- a negatively a (1->4)- a [protein]- (3R,5S)-3- O c-type BN6628_RS05255 asp levansucrase: 5-carboxylate a [protein]- a cis- 1-palmitoylglycerol a glycogen a 3'-half-tRNA a nucleoside NMN 2 synthase: [tRNA ] 1,1-kestotetraose 6 -kestotriose BN6628_RS16815 BN6628_RS04515 reductase QueF: dependent, methylguanine molecule with deoxyribonucleoside [DNA] a tRNA sec ser oxotetracos- α-D-glucan hydroxy-1- a reduced BN6628_RS09370 acetyltransferase G dehydratase asp to form a recombinational junction in 16S rRNA supercoiled DNA L-arginine cytochrome asp BN6628_RS24770 met L-cysteine vaccenoyl-[acp] 3-phosphate molecule with triphosphate BN6628_RS12865 dCMP tRNA β-ketopalmityl- BN6628_RS05965 subunit crossover junction in DNA glycogen/starch/ a 2',3'-cyclic 5'-triphosphate 16S rRNA bifunctional 5-enoyl-[acp]3-oxoacyl-ACP DNA 1,4-alpha-glucan pyrroline-5- H O c-type adenylate kinase: 2'-deoxyuridine GlmU: glmU FabZ: fabZ acyl-CoA methionine methylated-DNA-- 1-acyl-sn-glycerol- a 5'-OH end DNA polymerase nucleoside triphosphate serine--tRNA ligase: protein 2 (d)CMP kinase: [acp] preQ beta: sdaAB endodeoxyribonuclease alpha-glucan phosphate end (cytosine(1402)-N(4) metallophosphatase/ reductase: topoisomerase branching carboxylatepyrroline-5- CtaD cytochrome BN6628_RS21450 dTMP UDP-N-acetyl- thioesterase: 1 [protein]-cysteine S- 3-phosphate 2'-5' RNA ligase: III subunit delta: pyrophosphohydrolase: BN6628_RS17755 arginine kinase: an oxidized GDP 1,6-kestotetraose a (2E)-octadec- gamma-lyase: RuvC: BN6628_RS06760 phosphorylase: )-methyltransferase 5'-nucleotidase: IV subunit B: parE protein GlgB: thymidine kinase: BN6628_RS10290 α-D-glucosamine synthase: fabF BN6628_RS18880 L-serine methyltransferase: acyltransferase: BN6628_RS01400 BN6628_RS07745 BN6628_RS25275 serine--tRNA ligase: BN6628_RS05720 BN6628_RS21715 carboxylate O c-type dTMP kinase: 2-enoyl-[acp] a 2,3,4-saturated tRNA guanosine(34) L-glutamate-5- BN6628_RS03110 glycine cleavage BN6628_RS15470 a ligated tRNA RsmH: mraW BN6628_RS19015 BN6628_RS11530 a [protein]- 2 (2Z)-2-aminobut- Holliday junction resolvase BN6628_RS14770 BN6628_RS10295 α [+ 9 isozymes] BN6628_RS00290 an N 4 - β [+ 8 isozymes] [+ 2 isozymes] α reductase: cytochrome BN6628_RS25135 BN6628_RS05555 dCDP a 3-oxohexadecanoyl- fatty acid transglycosylase ammonia- semialdehyde 1-palmitoyl-2- -D- a nucleoside 5'- 1-( -D a (3R,5Z)-3- a (1,6)- -D- ω met RS20120 met ADP steroyl-[acp] 2-enoate RuvX: BN6628_RS06970 a [protein]-S- with a 2'-5' linkage an L-seryl- 1402 N -phospho- proC tyrosine-- [acp] lyase, a [glycine-cleavage a guanine in DNA acyl-carrier protein cis-vaccenoyl glucopyranose an α-limit dextrin [DNA] methylcytidine ribofuranosyl) hydroxytetracos- a relaxed DNA glucosyl-(1,4) trans-4-hydroxy- thymidine tyr Tgt: resolution of recombinational junction methyl-L-cysteine monophosphate sec L-arginine dTDP dUMP nucleoside-diphosphate tRNA ligase: reductase: iron-sulfur- L-glutamate complex H protein] phosphatidate 1-phosphate [tRNA ] in 16S rRNA nicotinamide 5-enoyl-[acp] -α-glucan 3-oxoacyl-ACP BN6628_RS06785 formation of two intact strands L-proline nucleoside- kinase: BN6628_RS17985 BN6628_RS19425 an L-tyrosyl- BN6628_RS03485 dependent, gamma- N 6 -lipoyl-L-lysine EnpEP protein: reductase: a 7-aminomethyl-7- ribonucleotide- thymidylate synthase: thymidine kinase: nucleoside-diphosphate Tyr semialdehyde BN6628_RS00370 met RS10755 met diphosphate kinase: [tRNA ] deazaguanosine 34 subunit dihydrolipoyl diphosphate ribonucleotide- Tyr BN6628_RS05720 a stearoyl-[acp] dehydrogenase: 4 BN6628_RS17985 BN6628_RS11470 BN6628_RS05555 kinase: BN6628_RS10395 a tRNA beta: sdaAB 2-iminobutanoate dehydrogenase: gcv system: an N 6 -L- an O - 1-cis- an [amino group carrier protein]- 2-(2-carboxy-4- cyclic a (6Z)-3- 2-trans, 4-trans in tRNA 2-aminoprop- a sulfurated a [protein]- a cis- 3-oxo- a [protein]-L- a [protein]- reductase ribonucleoside- diphosphate thymidylate synthase: [+ 8 isozymes] pruA 37 methylthymine C-terminal-γ-(L-glutamate 5- methylthiazol-5- HMP-PP dehypoxanthine cob(I)yrinate hydantoin oxooctadec- -undecadienoyl- riboflavin nucleoside- dCTP a (3R)-3- tRNA preQ1(34) S- lpdA lpdA threonylcarbamoyladenine L-cysteine vaccenoylglycerol- ATP docosapentaenoyl-CoA acyl-carrier protein methionine L-histidine nucleoside- subunit beta: diphosphate reductase ribonucleoside- BN6628_RS12865 2-enoate [sulfur carrier] in DNA vaccenoyl-[acp] semialdehyde-2-yl)-L-glutamate yl)ethyl phosphate futalosine a,c-diamide 3-oxoacyl-[acyl- 6-enoyl-[acp] CoA peptide-methionine bifunctional diphosphate kinase: hydroxyhexadecanoyl- adenosylmethionine dihydrolipoyl in tRNA tRNA (N(6)-L- methylated-DNA-- 1-acyl-sn-glycerol-3-phosphate N-acetyl-gamma- thiamine phosphate 1,4-dihydroxy- hydantoinase 3-oxoacyl-ACP histidine kinase: gln RS13955 gln diphosphate kinase: BN6628_RS02700 reductase subunit beta: diphosphate Glu ATP:cob(I)alamin carrier-protein] ACP S- 2,4-dienoyl- (S)-S-oxide riboflavin BN6628_RS10395 Aromatic Compound Biosynthesis [acp] ribosyltransferase- dehydrogenase: threonylcarbamoyladenosine(37) [protein]-cysteine S- 3-phosphate glutamyl-phosphate synthase: 6-naphthoate subunit beta: reductase: BN6628_RS09040 BN6628_RS17985 ribonucleoside- subunit alpha: F0F1 ATP synthase BN6628_RS02700 reductase a [glycine-cleavage adenosyltransferase: reductase: malonyltransferase: CoA reductase: reductase: kinase/FAD tryptophan- 3-hydroxyacyl- isomerase QueA: lpdAa [glycine-cleavage -C(2))- methylthiotransferase methyltransferase: acyltransferase: reductase: BN6628_RS11420 synthase: BN6628_RS12700 BN6628_RS05720 [+ 8 isozymes] nucleoside- diphosphate BN6628_RS02705 subunit epsilon: subunit alpha: dTTP stearate 2-oxobutanoate complex H protein] N 6 - thiamine adenosyl-BN6628_RS06265 BN6628_RS16815 BN6628_RS13130 BN6628_RS07240 BN6628_RS01680 a [protein]- synthetase: ribonucleoside- xanthine and -tRNA BN6628_RS06780 6 MtaB: BN6628_RS07850 6 BN6628_RS10295 BN6628_RS21950 [+ 8 isozymes] chorismate biosynthesis I [acyl-carrier- complex H protein] N a 2-methylsulfanyl-N -L- BN6628_RS14770 1,2-dicis- an [amino group carrier protein]- BN6628_RS15185 (5Z,8Z,11Z,14Z,17Z) a (3R,6Z)-3- (3E)-undec- a protein-L- Cd 2+ CadA Cd 2+ diphosphate kinase: reductase [+ 2 isozymes] BN6628_RS22230 diphosphate BN6628_RS02705 dTMP ligase: trpS 2-iminopropanoate aminomethyldihydrolipoyl- an unsulfurated a [protein]-S- phosphate an unknown 1,4-dihydroxy- PPP cobyrinate N-carbamoylglycine N-phospho- ribF xanthosine salvage 4-hydroxyphenylpyruvate protein] acyl-CoA an epoxyqueuosine 34 -dihydrolipoyl-L-lysine met 5'-deoxyadenosine threonylcarbamoyladenine 37 a thymine in DNA acyl-carrier protein vaccenoyl- C-terminal-γ-(5-phospho- i -3R-hydroxy- a malonyl-[acp] hydroxyoctadec- 3-enoyl-CoA methionine- BN6628_RS10395 subunit alpha: [+ 7 isozymes] reductase [+ 2 isozymes] dTMP kinase: tryptophan- biosynthesis synthetase: L-lysine [sulfur carrier] methyl-L-cysteine compound 6-naphthoate a,c-diamide L-histidine FMN Trp D-erythrose dehydratase in tRNA L-threonine in tRNA phosphatidate L-glutamyl)-L-glutamate docosapentaenoyl-CoA 6-enoyl-[acp] (S)-S-oxide BN6628_RS02705 subunit alpha: a tRNA BN6628_RS25135 -tRNA 4-phosphate FabZ: fabZ BN6628_RS13935 degradation II guanine and xanthosine epoxyqueuosine 2+ 2+ BN6628_RS02705 ligase: trpS an L-tryptophanyl- long-chain fatty L-glutamine Cd RS00385 Cd guanosine salvage dTDP bifunctional 3-deoxy-7- tyr a (2E)-hexadec- reductase: queG purine-nucleoside Trp aminomethyltransferase: 1-stearoyl- a linear malto- N-acetyl-D- β (12Z,15Z)-9,10- a SpoIVB [tRNA ] phosphoheptulonate aromatic amino acid 2-enoyl-[acp] acid--CoA ligase: pyruvate thr degradation I a [formate C icosapentaenoate coenzyme A an acyl-[acyl- -D-fructofuranose 1-[18-hydroxyoleyl]- 1-myristoylglycerol an aromatic a [protein]-L- an organic nucleoside-diphosphate phosphorylase: a queuosine 34 L-glutamate SAM a reduced flavodoxin sn-glycerol oligosaccharide galactosamine 3'-dephospho- epoxyoctadeca- GGPP IPP peptidase trp aminotransferase: BN6628_RS07225 L-threonine 3- lpdA ATP 1-phosphate 2-lyso-phosphatidate 3-phosphate amino acid methionine molecule kinase: BN6628_RS17985 BN6628_RS10070 synthase/ palmitoyl-[acyl- in tRNA degradation IX (via acetyltransferase]-glycine long-chain fatty acid--CoA carrier protein] 3-phosphate glycogen/starch/ 6-phosphate CoA fructose 1-acyl-sn-glycerol- 12,15-dienoate peptide-methionine cytochrome P450: Precursor guanosine BN6628_RS06255 pyruvate 1-acyl-sn-glycerol- N-acetylglucosamine- 1-acyl-sn-glycerol- heptaprenyl 2+ 2+ chorismate mutase: stearoyl-CoA dehydrogenase: gln alpha-glucan dephospho- aromatic amino acid SpoIVB Co RS13905 Co dGDP dADP purine-nucleoside nucleoside-diphosphate [+ 3 isozymes] 4-hydroxyphenylpyruvate carrier-protein] 4-aminobutanoate) formate-lyase ligase: BN6628_RS07225 3-phosphate 6-phosphate bisphosphate 3-phosphate epoxide hydrolase: 3-phosphate diphosphate (R)-S-oxide BN6628_RS17285 xanthine BN6628_RS16975 tdh asparagine phosphorylase: CoA kinase: aminotransferase: peptidase: phosphorylase: deoD kinase: BN6628_RS10395 reductase: L-2-amino-3- 1-activating acyl-CoA synthetase: acyltransferase: deacetylase: nagA aldolase: acyltransferase: BN6628_RS02340 acyltransferase: synthase: reductase: cytochrome P450: synthase Glu BN6628_RS15470 D-galactosamine BN6628_RS18790 BN6628_RS06255 spoIVB GTP ATP threonine-- 3-deoxy-7- BN6628_RS03485 oxobutanoate L-phenylalanine degradation I (aerobic) BN6628_RS13935 α BN6628_RS18090 BN6628_RS10295 (12Z,15Z)-9,10- BN6628_RS10295 BN6628_RS10390 BN6628_RS09610 BN6628_RS01590 [+ 3 isozymes] dTTP xanthine (glutamine- enzyme: pflA a [formate C BN6628_RS10295a 1-stearoyl 2- -D- acetate + 1-[18-hydroxyoeoyl]-2- all-trans- a protein-L- phosphoheptulonate glutamate a flavodoxin a linear malto- 6-phosphate ADP coenzyme A H dimyristoyl an aromatic a SpoIVB a cation RS20745 a cation nucleoside- nucleoside- guanine phosphoribosyltransferase: tRNA ligase: tRNA processing glycine C- hydrolyzing) met 5'-deoxyadenosine acetyltransferase]- icosapentaenoyl-CoA acyl-carrier protein acyl-sn-glycerol glucopyranose D-glyceraldehyde DHAP [18-hydroxy-lioleoyl]-sn dihydroxyoctadeca- heptaprenyl methionine- an alcohol synthase: aroF a palmitoyl-[acp] (6R)-4a-hydroxy- decarboxylase: semiquinone oligosaccharide phosphatidate 2-oxo-acid peptidase diphosphate kinase: diphosphate kinase: BN6628_RS17515 BN6628_RS19365 acetyltransferase: : asnB glycin -2-yl radical 3-phosphate 1-phosphate -glycerol 3-phosphate 12,15-dienoate diphosphate (R)-S-oxide 3-deoxy- Secondary Metabolite Biosynthesis tetrahydrobiopterin 4a-hydroxytetrahydrobiopterin BN6628_RS18900 anaerobic BN6628_RS17985 anaerobic BN6628_RS17985 xanthine threonine-- phosphatidylethanolamine a polycistronic BN6628_RS20310 xanthine thr D-arabino- [+ 7 isozymes] dehydratase: 4-aminobutanoate ribonucleoside- nucleoside- ribonucleoside- nucleoside- phosphoribosyltransferase: phosphoribosyltransferase: tRNA ligase: biosynthesis I tRNA precursor Glu a cation RS03105 a cation BN6628_RS17515 heptulosonate preQ biosynthesis gly BN6628_RS00340 a DNA containing 3-oxo- salicin 6- MoO - 3-oxo-2-(cis- (9Z,12Z)-15,16- 2-trans, 4-cis- triphosphate diphosphate kinase: triphosphate diphosphate kinase: BN6628_RS21070 0 S-methyl-L- an (R)-2-halocarboxylate a [protein]- a single a ribonucleoside 2 palmitoleoyl-CoA a DNA segment a phosphate BN6628_RS02895 an L-threonyl- 7-phosphate myo-inositol L-homocysteine S methyl (6Z,9Z,12Z,15Z,18Z,21Z) phosphate 2'-pentenyl)- epoxyoctadeca- undecadienoyl- propan-1-ol ala [+ 2 isozymes] Thr a CDP-diacylglycerol p L-cysteine stranded DNA triphosphate molybdopterin ATP monoester reductase: nrdD BN6628_RS10395 reductase: nrdD BN6628_RS10395 [tRNA ] biosynthesis methionine HAD family hydrolase: phosphotriester -tetracosahexaenoyl-CoA 6-phospho-beta- cyclopentane- 9,12-dienoate acyl-CoA recombinase XerC: CoA NAD(P)- Thr 3-dehydroquinate palmitate CDP-diacylglycerol--serine bifunctional homocysteine methylated-DNA-- DNA primase: acetyl-CoA C- cofactor alkaline a tRNA BN6628_RS11490 glucosidase: molybdenum cofactor 1-octanoate dehydrogenase: BN6628_RS11680 2,4-dienoyl- dependent alcohol alanine GMP XMP synthase: D-glucopyranose O-phosphatidyltransferase: (6R)-L-erythro-5,6,7,8- L-erythro-7,8- L-alanine S-methyltransferase/ [protein]-cysteine S- BN6628_RS07985 acyltransferase: 12-oxophytodienoate epoxide hydrolase: phosphatase: a cation RS05180 a cation GTP acyl-CoA a tRNA precursor a tRNA precursor BN6628_RS12230 guanylyltransferase: BN6628_RS07220 recombinase CoA reductase: dehydrogenase: racemase: BN6628_RS10430 6-phosphate pssA tetrahydrobiopterin dihydrobiopterin degradation IV methylenetetrahydrofolate HAD family hydrolase: methyltransferase: DNA primase: BN6628_RS13930 reductase: BN6628_RS02340 BN6628_RS11120 dGTP dATP GTP synthetase: a 3-sn-phosphatidyl- with a 5' with a 5' docosahexaenoyl- adenylyl BN6628_RS22405 RecA: recA BN6628_RS07240 BN6628_RS18080 alr reductase: BN6628_RS09355 BN6628_RS04600 BN6628_RS14770a DNA without BN6628_RS20190 acetyl-CoA [+ 2 isozymes] BN6628_RS23635 (9Z,12Z)-15,16- [+ 2 isozymes] a DNA segment [+ 3 isozymes] 3-dehydroquinate cyclohydrolase BN6628_RS13935 L-serine extension and extension and a a [protein]-S- ssDNA/pppN(pN) CoA β-D-glucose molybdenum (2E,9Z)- (3E)-undec- 7,8- met a halide anion an (R)-2-hydroxyacid S methyl salicyl alcohol 12-oxo-cis-10,15- dihydroxyoctadeca- in reverse 3-enoyl-CoA an alcohol 1-propanal D-ala serine--tRNA ligase: I FolE: folE a long 3' trailer short 3' extension ala methyl-L-cysteine p hybrid 6-phosphate cofactor hexadecenoyl-CoA a cation RS05655 a cation long-chain fatty phosphatidylserine n -1 phytodienoate 9,12-dienoate BN6628_RS17755 type II 3- dihydroneopterin Ins(3)P ribonuclease P phosphotriester orientation ser acid--CoA ligase: decarboxylase: psd Secondary Metabolite Degradation alanine Metabolic Regulator dehydroquinate 3'-triphosphate protein component: serine--tRNA ligase: inositol BN6628_RS07225 dehydrogenase: ald Biosynthesis dehydratase: aroQ 6-carboxytetrahydropterin an L-1- BN6628_RS25040 β a 2'- (9Z,15Z)-12,13- BN6628_RS00290 an L-seryl- ribonuclease PH: pyruvate a [2-oxoglutarate- a dolichyl - a [protein] N-terminal- arbutin-6- (7Z)- 34 synthase QueD: queD monophosphatase: phosphatidylethanolamine a tRNA precursor anhydromuropeptides recycling I icosapentaenoyl-CoA a ribonucleoside sn-glycerol butan-1-ol a cytidine a cation RS14370 a cation [tRNA ser ] palmitoyl-CoA BN6628_RS06300 dehydrogenase a sulfurated D-mannosyl a [protein] Ser/Thr met deoxyribonucleoside formate epoxy-octadeca- L-homoserine trp lys ppGpp biosynthesis 3-dehydroshikimate BN6628_RS00110 SAM formyl-L-methionine phosphate triphosphate hexadecenoyl-CoA 1-phosphate in tRNA Ile2 a tRNA ser 6-carboxy-5,6,7,8- with a short GlcNAc-1,6- E2 protein] N 6 - [sulfur carrier] acyl-CoA thioesterase: phosphate peptide 6-phospho-beta- 5'-monophosphate 9,15-dienoate acyl-CoA NAD(P)- inositol dolichyl-phosphate- methionine anaerobic sn-glycerol- tRNA(Ile) shikimate tetrahydropterin a tRNA 3' extension anhMurNAc- octanoyl-L-lysinelipoyl BN6628_RS18880 deformylase: def glucosidase: dehydrogenase: homoserine O- aromatic amino acid dependent alcohol monophosphatase: mannose--protein gamma-lyase: 5'-deoxynucleotidase: ribonucleoside- epoxide hydrolase: 1-phosphate -lysidine pppGpp dehydrogenase: precursor with L-Ala-γ-D-Glu- synthase: acyl-CoA thioesterase: peptide deformylase: BN6628_RS12230 BN6628_RS07220 succinyltransferase: aminotransferase: dehydrogenase: a cation RS16900 a cation 7-carboxy-7- BN6628_RS03490 a [2-oxoglutarate mannosyltransferase: BN6628_RS03110 BN6628_RS18830 triphosphate BN6628_RS02340 dehydrogenase: synthetase: a 5' extension ribonuclease PH: lipA BN6628_RS20955 BN6628_RS19445 BN6628_RS06255 BN6628_RS18080 peptidoglycan biosynthesis I (meso-diaminopimelate containing) Cell Structure Biosynthesis bifunctional (p)ppGpp aroE deazaguanine DAP-D-Ala an unsulfurated dehydrogenase BN6628_RS04515 a 3-O-(α-D- BN6628_RS22580 2-oxobutanoate methanethiol [+ 2 isozymes] reductase: nrdD (9Z,15Z)-12,13- [+ 2 isozymes] BN6628_RS15820 tilS an N-terminal L- β-D-glucose a 2'- (2E,7Z)- (indol-3- 34 proline--tRNA ligase: BN6628_RS06300 5'-deoxyadenosine met 6 a dolichyl a 2'-deoxyribonucleoside O-succinyl-L- a lysidine vancomycin resistance II synthetase/guanosine- synthase myo-inositol ribonuclease: [sulfur carrier] E2 protein] N coenzyme A icosapentaenoate mannosyl)-(Ser/ formate hydroquinone deoxyribonucleoside dihydroxyoctadeca- yl)pyruvate DHAP butan-1-al UDP-N-acetyl- BN6628_RS06000 shikimate phosphate methionyl-[protein] 6-phosphate 5'-triphosphate hexadecenoyl-CoA homoserine in tRNA Ile2 3',5'-bis(diphosphate) 3'- guanosine 3'- QueE: queE -lipoyl-L-lysine Thr)-[protein] 9,15-dienoate K + KdpB K + α pro BN6628_RS25040 -D-glucosamine pyrophosphohydrolase: diphosphate 5'- proline--tRNA ligase: 7-carboxy-7- D-alanyl-D-alanine shikimate kinase: N-acetyl-β-D- L-alanyl-γ-D- UDP-N-acetylglucosamine ser BN6628_RS06850 triphosphate 3'- BN6628_RS16395 an L-prolyl- deazaguanine BN6628_RS09185 glucosamine-1,6- glutamyl-meso-2,6- a [pyruvate a plant soluble a 2-deoxystreptamine an (S)-2- 4,8,12- 37 1-carboxyvinyltransferase: D-alanyl-D-alanine [+ 2 isozymes] diphosphatase: [tRNA Pro ] Polymeric Compound Degradation a 1-phosphatidyl- a dihydroceramide sn-glycero-3- a [protein] Ser/Thr a 1-phosphatidyl- a folate adenine ethanol butan-1-ol selenide 7-cyano-7- dehydrogenase a sulfurated trimethyltridecanoyl- val ethylphosphate + + Pro anhydro-N-acetyl- diaminopimeloyl- 1D-myo-inositol phosphoethanolamine heteroglycan antibiotic halocarboxylate 1D-myo-inositol in tRNA K RS02825 K murA dipeptidase: BN6628_RS06850 a tRNA shikimate 3- an uncharged SAM 6 1 deazaguanine β-D-muramate D-alanine E2 protein] N - [sulfur carrier] inositol glycerophosphodiester glycogen/starch/ aminoglycoside N(3) haloacid CoA serine/threonine dihydrofolate tRNA1(Val) NAD(P)- NAD(P)- selenide, [+ 2 isozymes] BN6628_RS05745 phosphate tRNA lipoyl phosphatidylinositol acid phosphatase: synthase beta-N- LD- chitin degradation II (Vibrio) octanoyl-L-lysine phosphorylceramide phosphodiesterase: alpha-glucan -acetyltransferase: dehalogenase: sterol carrier protein: protein kinase: kinase: reductase: (adenine(37)-N6)- dependent alcohol dependent alcohol water UDP-N-acetyl-α- 3-phosphoshikimate 1- QueC: queC heparin degradation synthase: phosphorylase: BN6628_RS11280 BN6628_RS09415 BN6628_RS11475 BN6628_RS03135 dikinase: acetylhexosaminidase: carboxypeptidase: a [pyruvate synthase: BN6628_RS17790 BN6628_RS04410 BN6628_RS07235 BN6628_RS05935 methyltransferase: dehydrogenase: dehydrogenase: D-glucosamine- D-ala D-serine carboxyvinyltransferase: lipA 3 [+ 4 isozymes] GTP ppGpp BN6628_RS13815 chitin BN6628_RS06795 [+ 2 isozymes] BN6628_RS15470 an N -acetyl-2- [+ 4 isozymes] [+ 4 isozymes] a 1-phosphatidyl- [+ 2 isozymes] 6 BN6628_RS25165 BN6628_RS18080 BN6628_RS18080 selD predicted preQ BN6628_RS09745 an unsulfurated dehydrogenase α 3-oxopristanoyl- an N - enolpyruvate phenylalanine- aroA 0 L-alanyl-γ-D- heparin 5'-deoxyadenosine met a 1,2-diacyl- an inositol sn-glycerol -D-glucopyranose a plant soluble deoxystreptamine antibiotic an (R)-2- a [protein] (L-serine/L- 1D-myo-inositol ethanol ATP-driven beta-N- [sulfur carrier] E2 protein] N 6 ethanolamine a halide anion a 7,8-dihydrofolate methyladenine 37 acetaldehyde butan-1-al selenophosphate K + K + UDP-N- -tRNA ligase 5-enolpyruvoyl- glutamyl-meso- chitinase: heparinase: sn-glycerol phosphodihydroceramide 3-phosphate 1-phosphate heteroglycan hydroxyacid CoA threonine) phosphate 4-phosphate transporter D-alanine--D-serine nucleoside- lipoprotein posttranslational acetylhexosaminidase: -lipoyl-L-lysine in tRNA val acetylenolpyruvoylglucosamine GTP subunit alpha: shikimate 3- BN6628_RS07490 BN6628_RS15685 1 diphosphate kinase: modification diaminopimelate of K+ reductase: BN6628_RS08215 ligase VanG: vanB pyrophosphokinase: BN6628_RS06185 phosphate BN6628_RS01500 [+ 3 isozymes] BN6628_RS17985 heparinase: BN6628_RS13795 chorismate a [prolipoprotein]- 1,6-anhydro-N- + + UDP-N-acetyl- phenylalanine- BN6628_RS18555 undecaprenyl-diphospho-N D-cellobiose a [protein]- an organic (7Z)- a (1->4)- 1-oleyl-2-lyso- Na RS07860 Na nucleoside- bifunctional (p)ppGpp L-cysteine β a chitodextrin 4-deoxy-2-O-sulfo- a pseudouridine 1915 in 23S rRNA maltohexaose stearoyl-CoA H O sucrose a levan a ribonucleoside vernolate enterobactin 5-hydroxy- ala synthase: acetyl- -muramate -acetylmuramoyl-L-alanyl-γ- UDP-N-acetyl-α-D-glucosamine 2 α-D-glucan phosphoenol α-D-muramate D-alanyl-D-serine GTP synthetase/guanosine- -tRNA ligase β-L-erythro-hex-4- 6'-phosphate L-cysteine hydroperoxide 5'-monophosphate tetradecenoyl-CoA phosphatidate L-tryptophan dGDP diphosphate kinase: phe BN6628_RS10425 prolipoprotein D-glutamyl-L-lysyl- D-alanine 23S rRNA 6-phospho-beta- glycogen/starch/ peroxiredoxin: acyl-CoA thioesterase: levansucrase: acyl-CoA 1,4-alpha-glucan 1-acyl-sn-glycerol- pyruvate Glu pyrophosphokinase: 3',5'-bis(diphosphate) 3'- subunit beta: fructoselysine and enopyranuronosyl-(1,4)-D-N undecaprenyldiphospho- bifunctional enterobactin UDP-N- BN6628_RS10395 BN6628_RS17560 BN6628_RS06190 diacylglyceryl (pseudouridine(1915)- glucosidase: alpha-glucan BN6628_RS06125 BN6628_RS04515 BN6628_RS24765 epoxide hydrolase: dehydrogenase: branching 3-phosphate aromatic acid pyruvate pyrophosphohydrolase: an L-phenylalanyl- psicoselysine degradation muramoylpentapeptide beta-N- metallophosphatase/ esterase: + + acetylmuramate-- chorismate transferase: -sulfoglucosamine 6-O-sulfate BN6628_RS12230 phosphorylase: BN6628_RS02340 BN6628_RS07220 protein GlgB: decarboxylase: Na RS02980 Na [tRNA Phe ] N-acetyl-D- acetylglucosaminyltransferase: N(3))-methyltransferase [+ 2 isozymes] acyl-CoA thioesterase: levansucrase: 5'-nucleotidase: BN6628_RS04895 acyltransferase: kinase: pyk glutamate racemase: BN6628_RS06850 N 6 -(D-psicosyl) an intra- BN6628_RS11530 BN6628_RS10380 L-alanine ligase: a tRNA Phe BN6628_RS00790 muramate 6- a chitodextrin murG RlmH: BN6628_RS24725 [+ 2 isozymes] BN6628_RS15470 an alcohol BN6628_RS18880 BN6628_RS24770 BN6628_RS19015 (9Z)-12,13- [+ 2 isozymes] N-(2,3- BN6628_RS10295 BN6628_RS17855 a [prolipoprotein]- -L-lysine ditrans,octacis-undecaprenyldiphospho- an N 3 -methylpseudouridine 1915 D-glucopyranose α-D-glucopyranose protein disulfide (2E,7Z)- dioleoyl dGTP pyruvate BN6628_RS06525 GDP phosphate fructoselysine D-glucopyranose maltopentaose stearate D-glucopyranose a levan a ribonucleoside dihydroxyoctadeca- dihydroxybenzoyl) a GlgE-glycogen serotonin UDP-N-acetyl- (S-diacylglyceryl) 4-deoxy-β-L-erythro-hex-4- UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- in 23S rRNA 6-phosphate 1-phosphate tetradecenoyl-CoA phosphatidate N-acetylmuramic 3-epimerase: γ 9-enoate -L-serine Peptide RS08125 Peptide α D-glt -L-cysteine L-alanyl- -D-glutamyl-L-lysyl-D-alanine -D-muramoyl- acid 6- BN6628_RS24245 enopyranuronosyl-(1,4)-D-N N 6 -(D-fructosyl) L-alanine phosphate -sulfoglucosamine 6-O-sulfate methionine-- lipoprotein -L-lysine decaprenyl-diphospho-N- UDP-N-acetyl- 3-[(1- methyl β-D-glucoside 5-dehydro-4-deoxy- (5Z)- a [protein]- met etherase: murQ beta-N- sucrose 6-kestotriose a maltodextrin 3-oxo-(9Z)- an acyl-CoA H O an aliphatic amine 2-deoxygluconate UDP-N- tRNA ligase: signal peptidase: α 2 D-glucuronate L-tyrosine phosphoenol Peptide RS24945 Peptide an L-methionyl- N-acetyl-D- fructoselysine acetylhexosaminidase: acetylmuramoyl-pentapeptide -D-glucosamine a tRNA precursor CTP ATP octadecenoyl-CoA SAM carboxyvinyl) 6-phosphate tetradecenoyl-CoA biotin ATP dADP acetylmuramoyl- BN6628_RS09760 BN6628_RS08305 undecaprenyldiphospho- levansucrase: glycogen/starch/ acetyl-CoA C- acyl-CoA thioesterase: 6-phospho-beta- 5-dehydro-4-deoxy- acyl-CoA copper amine 2-deoxy-D- phosphate pyruvate [elongator glucosamine 6-kinase: BN6628_RS01500 oxy]benzoateaminofutalosine L-alanine--D- muramoylpentapeptide beta-N- CCA tRNA BN6628_RS24770 alpha-glucan acyltransferase: BN6628_RS18880 glucosidase: D-glucuronate dehydrogenase: oxidase: biotin--[acetyl-CoA- gluconate 3- protein tyrosine elongator Met 6-phosphate BN6628_RS12930 N,6-O-disulfo-D-glucosamine synthase MqnE: pyruvate glutamate ligase: tRNA ] an (S-diacyl- a lipoprotein beta-N- acetylglucosaminyltransferase: nucleotidyltransferase: phosphorylase: BN6628_RS13930 BN6628_RS12230 isomerase: BN6628_RS07220 BN6628_RS06285 carboxylase] ligase: phosphatase: tRNA Met N-acetylglucosamine- levansucrase: acyl-CoA thioesterase: BN6628_RS20080 dehydrogenase: kinase: pyk BN6628_RS08200 sn-glyceryl) signal peptide [+ 2 isozymes] acetylhexosaminidase: murG a tRNA BN6628_RS10595 BN6628_RS15470 (7Z)- BN6628_RS18575 BN6628_RS10600 BN6628_RS00565 Peptide RS07320 Peptide 6-phosphate N 6 -(6-phospho- BN6628_RS24765 acetyl-CoA BN6628_RS04515 6-amino-6- [+ 2 isozymes] [+ 2 isozymes] [+ 5 isozymes] biotinyl-5'- kduD -L-cysteinyl- N,N'- BN6628_RS09745 N,N',N''- decaprenyl-pyrophosphoryl- containing a α-D-glucopyranose hexadecenoyl-CoA met β-D-glucose 3-deoxy-D-glycero- (2E,5Z)- 3-dehydro-2- a [protein]- dATP pyruvate deacetylase: nagA D-fructosyl) D-glucopyranose 6,6-kestotetraose a maltodextrin a carboxylate deoxyfutalosine MeOH an aldehyde adenylate UDP-N-acetyl- [apolipoprotein] diacetylchitobiose triacetylchitotriose UDP (N-acetylglucosamine)-N- 3' CCA end 1-phosphate 6-phosphate 2,5-hexodiulosonate tetradecenoyl-CoA deoxy-D-gluconate L-tyrosine meso- -L-lysine α-D-muramoyl-L- D-glucosamine N-sulfo-D-glucosamine acetylmuramyl-(pentapeptide) diaminopimelate lysine- beta-N- predicted alanyl-D-glutamate a tRNA Lys 6-phosphate -tRNA acetylhexosaminidase: ABC efflux a peptide phosphoglucosamine BN6628_RS09745 ligase: lysS an N-acyl-(S- β-D-glucose seleno-L- quinoxaline-2- maltoheptaose 3-oxo-(7Z)- lauroyl-CoA H O an insertion sequence cis-vaccenoyl-CoA DNA with lesion histidinol thiol transporter thiol UDP-N- an L-lysyl- mutase: acyl-carrier protein 2 porphobilinogen NaMN DMKH an alcohol thr diacyl-sn-glyceryl) lys beta-N- 4'-phosphopantetheine ATP hexadecenoyl-CoA element IS30 2 of a thiol acetylmuramoyl- [tRNA Lys ] BN6628_RS21270 6-phosphate homocysteine carboxyl adenylate glycogen/starch/ acetyl-CoA C- acyl-CoA thioesterase: bifunctional acyl-CoA excinuclease NAD(P)- -L-cysteinyl- acetylhexosaminidase: acyl carrier hydroxymethylbilane demethylmenaquinone histidinol group L-alanyl-D- lys D-glucosamine 5-methyltetrahydropteroyltriglutamate- pantetheine-phosphate alpha-glucan acyltransferase: BN6628_RS04515 transposase: metallophosphatase/ dehydrogenase: ABC subunit UvrA: dependent alcohol L-threonine 3- D-ala [lipoprotein] D-glucosamine BN6628_RS01500 protein: acpP synthase: methyltransferase: dehydrogenase: glutamate--2, 6- - homocysteine S- adenylyltransferase: phosphorylase: BN6628_RS13930 BN6628_RS11235 5'-nucleotidase: BN6628_RS07220 BN6628_RS10870 dehydrogenase: dehydrogenase: 1-phosphate N-acetyl-D- a quinoxaline-2- acyl-CoA thioesterase: BN6628_RS06485 BN6628_RS10370 hisD predicted diaminopimelate methyltransferase: metE BN6628_RS16860 BN6628_RS15470 (5Z)- an insertion BN6628_RS19015 BN6628_RS18080 tdh D-alanine--D- bifunctional UDP-N- glucosamine AMP carboxyl-[aryl- acetyl-CoA BN6628_RS18880 [+ 2 isozymes] [+ 5 isozymes] ABC efflux ligase: 3'-dephospho-CoA α-D-glucopyranose tetradecenoyl-CoA preuroporphyrinogen sequence IS30 with β-D- (2E,11Z)- DNA without MQH his alanine ligase: acetylglucosamine SeMet carrier protein] maltohexaose laurate 2 an aldehyde aminoacetone thiol transporter thiol BN6628_RS08185 histidine-- mannitol degradation I 1-phosphate integrated transposon ribosylnicotinate octadecenoyl-CoA lesion BN6628_RS13300 peptidoglycan maturation (meso-diaminopimelate containing) his diphosphorylase/ of a thiol tRNA ligase: glucosamine-1- group UDP-N-acetyl- D-alanine--D- lipid II (meso BN6628_RS06890 D-mannitol an L-histidyl- phosphate N- 6 alanine ligase: diaminopimelate containing) 1-phosphate an N -L- 10 UDP-N-acetylmuramoyl-L- an α(1,5)- sulfate RS05810 sulfate α-D-muramoyl- [tRNA His ] mannitol-1- 4a-hydroxy-N - 3-oxo-(9Z)- a [protein]-L- long chain acetyltransferase 37 a glycogen oleoyl-CoA H O uroporphyrinogen-III oleoyl-CoA D-glycerate γ BN6628_RS03470 His threonylcarbamoyladenine alanyl-γ-D-glutamyl-meso-2,6- 2 L-arabinan met ω thr L-dopa L-alanyl- -D- peptidoglycan a tRNA GlmU: glmU phosphate 5- formyltetrahydrofolate hexadecenoyl-CoA proline ( = 180) polyphosphate glutamyl-meso-2,6- glycosyltransferase: in tRNA 4a-hydroxytetrahydrobiopterin diaminopimeloyl-D-alanineLD- glycogen/starch/ acetyl-CoA C- acyl-CoA thioesterase: uroporphyrinogen-III alpha-N- acyl-CoA peptidylprolyl D-glycerate D-alanyl-D-alanine α dehydrogenase: tRNA aromatic amino acid threonine aromatic acid diaminopimelate BN6628_RS07005 N-acetyl- -D- dehydratase: carboxypeptidase: alpha-glucan acyltransferase: BN6628_RS04515 C-methyltransferase: arabinofuranosidase: dehydrogenase: isomerase: dehydrogenase: polyphosphate glucosamine BN6628_RS22955 threonylcarbamoyladenosine phosphorylase: BN6628_RS15780 aminotransferase: dehydratase: decarboxylase: predicted a nascent peptidoglycan BN6628_RS00340 α BN6628_RS13815 BN6628_RS13930 acyl-CoA thioesterase: cobA BN6628_RS07220 BN6628_RS06425 BN6628_RS05945 kinase 1: ppk1 1-phosphate F6P dehydratase: BN6628_RS06900 UDP-N-acetyl- -D-muramoyl- BN6628_RS15470 (7Z)- BN6628_RS06255 BN6628_RS03715 BN6628_RS10380 ABC UDP-N- with (L-alanyl-γ-D-glutamyl- Inorganic Nutrient Metabolism a cyclic N 6 -L- 10 γ acetyl-CoA BN6628_RS18880 [+ 2 isozymes] [+ 2 isozymes] [+ 3 isozymes] sulfate sulfate glycine- an N -formyl- L-alanyl- -D-glutamyl- D-ala α-D-glucopyranose tetradecenoyl-CoA α-L- 4-(methylsulfanyl) (2E,9Z)- a [protein]-L- long chain transporter acetylmuramoyl- meso-2,6-diaminopimeloyl-D- bifunctional UDP-N- threonylcarbamoyladenosine maltotetraose oleate precorrin-2 hydroxypyruvate 2-oxobutanoate dopamine -tRNA 7,8-dihydrofolate meso-2,6-diaminopimelate 1-phosphate arabinofuranose -2-oxobutanoate octadecenoyl-CoA proline (ω = 0) polyphosphate of sulfate tripeptide--D-alanyl- alanyl-D-alanine) pentapeptide acetylglucosamine selenate reduction 37 in tRNA ligase diphosphorylase/ sulfate reduction D- alanine ligase: sulfate RS23020 sulfate subunit glucosamine-1- III (assimilatory) BN6628_RS08190 alpha: a glucosylated selenate 10 lipid II (meso 4-hydroxybenzoyl- 2,5-dichloro-trans a double phosphate N- urea cycle an N - an L-methionyl- maltopentaose a colanic acid lipid A-core meso- + a D-hexose glyQ sulfate NaMN 5,6-dimethylbenzimidazole diaminopimelate acetyl-CoA a protein NAD NADPH D-glycerate glycogenin phytol UDP-N-acetyl- acetyltransferase sulfate [initiator tRNA Met ] CoA -dienelactone stranded DNA a nascent peptidoglycan a nascent peptidoglycan a mature peptidoglycan with nicotinate-nucleotide-- formyltetrahydrofolate glycogen/starch/ acetyl-CoA C- O-antigen diaminopimelate NAD/NADP DNA gyrase 1,4-alpha-glucan NAD(P)- α-D-muramoyl- γ γ glycine--tRNA GlmU: glmU adenylyltransferase: sat sulfate methionyl-tRNA containing) peptidoglycan dienelactone X-Pro dipeptidyl- D-glycerate glucokinase: biotin RS13940 biotin with (L-alanyl- -D-glutamyl- with D,D cross-links (meso- (L-alanyl- -D-glutamyl-meso- gly adenosine 5'- ammonium dimethylbenzimidazole alpha-glucan acyltransferase: ligase domain- diaminopimelate transhydrogenase subunit A: branching dependent alcohol L-alanyl-γ-D- ligase subunit beta: adenylyltransferase: sat arg formyltransferase: glycosyltransferase: hydrolase: peptidase: dehydrogenase: BN6628_RS00955 meso-2,6-diaminopimeloyl- diaminopimelate containing) 2,6-diaminopimeloyl-D-alanyl- UDP-N-acetyl- phosphoselenate phosphoribosyltransferase: phosphorylase: BN6628_RS13930 containing protein: dehydrogenase: alpha subunit: BN6628_RS10930 protein GlgB: dehydrogenase: glutamyl-meso-2,6- di-trans,octa-cis D-alanine) tetrapeptide D-alanine) pentapeptide BN6628_RS07975 α-D-glucosamine APS an N-formyl- BN6628_RS09395 lipid II (meso di-trans,octa-cisBN6628_RS07005 BN6628_RS12620 BN6628_RS22740 BN6628_RS05945 a glycyl-[tRNA Gly ] phosphoadenylyl- carbamoyl- cobT BN6628_RS15470 4-hydroxybenzoyl- BN6628_RS23215 BN6628_RS02440 BN6628_RS10805 [+ 2 isozymes] BN6628_RS11530 BN6628_RS18080 diaminopimeloyl- -undecaprenyl UDP-N-acetylglucosamine phosphate synthase α L-methionyl- a tetrahydrofolate diaminopimelate -undecaprenyl α acetyl-CoA a peptide a dipeptide (S)-2,3,4,5- D-hexose 6- acetate acetate Gly sulfate reductase: phosphoadenylyl- -ribazole -D-glucopyranose E. coli M 2,5-dichloromaleylacetate + a negatively hydroxypyruvate a glycogen D-alanyl-D-alanine L,D-transpeptidase: LD-carboxypeptidase: a tRNA argininosuccinate nicotinate [initiator tRNA met ] containing) diphosphate maltotetraose LPS NADP NADH phosphate phytenal phosphate a mature peptidoglycan 1-carboxyvinyltransferase: BN6628_RS21375 sulfate reductase: small subunit: 5'-phosphate 1-phosphate tetrahydrodipicolinate supercoiled DNA RS10985 BN6628_RS17025 BN6628_RS13815 lyase: argH with D,D cross-links (meso- murA BN6628_RS21375 BN6628_RS08335 a cation a cation L,D-transpeptidase: a nascent peptidoglycan a mature peptidoglycan selenite a nascent peptidoglycan with diaminopimelate containing) [+ 2 isozymes] carbamoyl- sulfite RS14425 sulfite BN6628_RS17570 with (L-alanyl-γ-D-glutamyl- with (L-alanyl-γ-D-glutamyl- sulfite a debranched 746 γ UDP-N-acetyl-α- L-arginino- phosphate synthase 2-amino-6-[1-hydroxyethyl]- a ring-opened 7- N-acetyl-4-O- 3-oxochol-4- uridine (L-alanyl- -D-glutamyl-meso- meso-2,6-diaminopimeloyl- meso-2,6-diaminopimeloyl- L-ornithine a sulfurated 3-phosphonopyruvate uroporphyrinogen-I α cis-dienelactone cyanophycin D-mannitol reduced riboflavin undecaprenyldiphospho- methionine-- D-glucosamine- succinate large subunit: 7-methyl-7,8-dihydropterin methylguanine in DNA hydrogen cyanide ATP cobinamide acetylneuraminate arg en-24-oyl-CoA -limit dextrin in 23S rRNA a nascent peptidoglycan 2,6-diaminopimelate) tripeptide glycine) tetrapeptide D-alanine) tetrapeptide met assimilatory sulfite DNA- [sulfur carrier] sialate O- glycogen/starch/ NAD(P)- N-acetylmuramoyl-L- tRNA ligase: enolpyruvate BN6628_RS08340 2-amino-4-hydroxy-6- rhodanese domain- nitric oxide uroporphyrinogen 23S rRNA dienelactone FMN γ with L,D cross links (meso- reductase (NADPH) formamidopyrimidine ATP:cob(I)alamin acetylesterase: phosphonopyruvate sterol carrier protein: alpha-glucan cyanophycinase: dependent alcohol alanyl- -D-glutamyl-meso BN6628_RS09760 an L-methionyl- UDP-N- hydroxymethyldihydropteridine containing protein: synthase: decarboxylase: pseudouridine hydrolase: reductase sulfite RS02645 sulfite diaminopimelate containing) selenodiglutathione flavoprotein subunit: carbamoyl glycosylase: mutM adenosyltransferase: BN6628_RS17430 decarboxylase: aepY BN6628_RS07235 phosphorylase: BN6628_RS02250 dehydrogenase: -2,6-diaminopimeloyl- [initiator tRNA Met ] diphosphokinase: folK 2,6-diamino-4- BN6628_RS14895 BN6628_RS14160 BN6628_RS17810 synthase F: BN6628_RS12620 (NADPH) acetylenolpyruvoylglucosamine BN6628_RS14290 phosphate an apurinic site BN6628_RS15470 BN6628_RS18080 D-alanyl-D-alanine a mature peptidoglycan with a mature peptidoglycan initiator tRNA Met ornithine [1-(2-amino-7-methyl-4-oxo- hydroxy-5-(N-methyl) an unsulfurated BN6628_RS06265 acetate N-acetylneuraminate 3,24-dioxocholest- BN6628_RS00320 [L-Asp(4-L- : ssuE γ reductase: BN6628_RS08215 argininosuccinate within DNA thiocyanate PPP adenosylcobinamide phosphonoacetaldehyde nitric oxide L-citrulline coproporphyrinogen I α-D-glucopyranose a pseudouridine 746 2-maleylacetate aldehydo- UDP-N- (L-alanyl- -D-glutamyl-meso- γ carbamoyltransferase: 7,8-dihydro-3H-pteridin- [sulfur carrier] i with (L-alanyl- -D-glutamyl- UDP-N-acetyl- hydrogen sulfide synthase: formamidopyrimidine 4-en-26-oyl-CoA 1-phosphate Arg)] dipeptide D-mannose riboflavin predicted acetylglucosamine- a mature peptidoglycan 2,6-diaminopimelate) tripeptide argF 6-yl)]ethyl diphosphate in 23S rRNA meso-2,6-diaminopimeloyl- α-D-muramate BN6628_RS21925 ABC -LPS N- with L,D cross-links (meso- glycine) tetrapeptide L-citrulline a sugar a sugar acetylglucosamine Amino Acid Biosynthesis glutathioselenol transporter diaminopimelate containing) 3-aci- transferase: an (R)-2-halocarboxylate a peptidoglycan a lipid II a [ThiI sulfur-carrier N-acetyl-9-O- N-methyl-L- DMKH2-10 2-chloro-trans L-arabinitol pyridoxal (R)-10- (2R,3S)-3- α-amylose (S)-malate of a sugar nitropropanoate cys acetylneuraminate VibB coenzyme A -dienelactone Hydroxystearate isopropylmalate BN6628_RS06065 L-histidine biosynthesis UDP-N-acetyl- 2-aminoethylphosphonate peptidoglycan protein]-L-cysteine tryptophan NAD(P)- 1,4-alpha-glucan superpathway of branched chain amino acid biosynthesis L-arginine biosynthesis II (acetyl cycle) superpathway of L- L-homoserine L-lysine biosynthesis III L-cysteine phosphate acquisition HAD family hydrolase: nitronate cysteine desulfurase: sialate O- N-methyl-L- holo-[acyl- demethylmenaquinone dienelactone 3-oxoacyl-[acyl- 3-isopropylmalate class II a sugar RS03170 a sugar [+ 2 isozymes] α-D-muramoyl- degradation I glycosyltransferase: dependent alcohol oleate hydratase: branching asparagine biosynthesis biosynthesis L-cysteine biosynthesis biosynthesis I BN6628_RS11490 monooxygenase: BN6628_RS24995 acetylesterase: tryptophan oxidase: carrier-protein] methyltransferase: hydrolase: carrier-protein] dehydrogenase: fumarate lipid II (meso L-alanyl-γ-D- BN6628_RS07005 dehydrogenase: BN6628_RS18010 protein GlgB: PRPP N-acetylglutamyl- VI (from L-methionine) hydrogen selenide a phosphate (2-aminoethyl) HAD family hydrolase: [unspecified BN6628_RS13835 di-trans,octa-cis [+ 3 isozymes] BN6628_RS17430 BN6628_RS02075 synthase: acpS BN6628_RS10370 BN6628_RS12620 reductase: leuB hydratase: diaminopimelate pyruvate asp glutamyl-meso-2,6- a [ThiI sulfur- BN6628_RS18080 BN6628_RS11530 thr phosphate asp monoester phosphonate2-aminoethylphosphonate- BN6628_RS04600 degradation nitrite 3-oxopropanoate -undecaprenyl a peptidoglycan acetate N-acetylneuraminate a holo-[VibB aryl- BN6628_RS16815 4-methyl-2- fumC containing) ATP asp aspartate kinase: ser diaminopimelate acid phosphatase: ala carrier protein]-S- trp formaldehyde 3',5'-ADP menaquinol-10 2-chloromaleylacetate oleate predicted acetolactate aspartate kinase: met serine O- -pyruvate a halide anion an (S)-2-hydroxycarboxylate products] diphosphate carrier protein] L-arabinopyranose 4-pyridoxolactone oxopentanoate amylopectin fumarate phosphoribosyltransferase BN6628_RS09835 BN6628_RS03135 sulfanyl-L-cysteine ABC synthase, threonine BN6628_RS09835 methionine acetyltransferase: transaminase: phnW a sugar a sugar regulatory subunit: dehydratase: aspartate kinase: phosphate transporter large subunit, asparagine asparagine aspartate kinase: adenosyltransferase: cysE phosphonoacetaldehyde BN6628_RS00815 BN6628_RS03715 bifunctional N-acetyl-gamma- BN6628_RS16300 thiosulfate of a sugar biosynthetic glutamate N- glutamyl-phosphate synthase synthase BN6628_RS16300 L-aspartyl- L-isoleucine BN6628_RS22105 O-acetyl-L-serine 6-trans-3-oxo- phosphoenol lysine within 2-chloro-cis- 3-oxo- 3-[(6'-methylthio) an organic a (1->4)- ATP (2Z)-2-aminobut- L-aspartyl- SAM disproportionation phosphonoacetaldehyde an (S)-2-halocarboxylate 2-methylbutanoate ethylnitronate (R)-lipoate DMKH2-11 2-phosphoglycolate α type: ilvB acetyltransferase/ reductase: (glutamine- (glutamine- 4-phosphate biosynthesis IV an acyl-carrier protein coenzyme A tridecenoyl-CoA pyruvate gcv protein H dienelactone icosatrienoyl-CoA hexyl]malate hydroperoxide -D-glucan tyr phosphoribosyltransferase: 2-enoate 4-phosphate cysteine IV (rhodanese) hydrolase: HAD family hydrolase: nitronate acetyl-CoA C- lipoate-- 1,4-alpha-glucan a sugar RS15580 a sugar [+ 2 isozymes] amino-acid BN6628_RS21950 hydrolyzing) hydrolyzing) acetate--CoA ligase: holo-[acyl- demethylmenaquinone dienelactone phosphoglycolate 3-oxoacyl-[acyl- 3-isopropylmalate peroxiredoxin: BN6628_RS00820 acetylglutamate synthase A: cysK BN6628_RS14995 BN6628_RS11490 monooxygenase: acyltransferase: phosphoenolpyruvate protein ligase: branching tyrosine acetyltransferase : asnB : asnB aspartate- aspartate- propanoate thiosulfate BN6628_RS09235 carrier-protein] methyltransferase: hydrolase: phosphatase: carrier-protein] dehydrogenase: BN6628_RS06125 kinase: argB glyphosate degradation II BN6628_RS13835 BN6628_RS13930 mutase: aepX BN6628_RS05835 protein GlgB: decarboxylase: 1-(5-phospho- (S)-2-acetolactate ArgJ: argJ N-acetyl-L- semialdehyde semialdehyde acyl-CoA [+ 2 isozymes] rhodanese domain- acetaldehyde HAD family hydrolase: [unspecified synthase: acpS a [glycine-cleavage BN6628_RS10370 BN6628_RS12620 BN6628_RS00210 reductase: leuB [+ 3 isozymes] β N-acetyl-L- 2-methylbutanoyl- 4-trans- BN6628_RS11530 tdc -D-ribosyl)-ATP Glu glutamate 5- dehydrogenase: synthetase: containing protein: BN6628_RS04600 AMP diphosphate degradation nitrite acetaldehyde acetyl-CoA complex H protein] BN6628_RS16815 9-(methylthio)- a sugar RS14825 a sugar ketol-acid glutamate dehydrogenase: cys CoA acyl-carrier protein 3',5'-ADP undecenoyl-CoA 3-phosphonopyruvate menaquinol-11 2-chloromaleylacetate glycolate 3R-hydroxy- an alcohol phosphoribosyl-ATP 2-iminobutanoate semialdehyde asn asn BN6628_RS16305 BN6628_RS13935 SAH BN6628_RS14895 glyphosate a halide anion an (S)-2-hydroxycarboxylate 6 a glycogen tyramine reductoisomerase: N-acetylornithine BN6628_RS16305 products] N -lipoyl-L-lysine icosatrienoyl-CoA 2-oxononanoate pyrophosphatase: long-chain fatty sulfite thiocyanate BN6628_RS06115 aminotransferase: L-aspartate- glycine oxidase BN6628_RS00850 L-aspartate- acid--CoA ligase: (2R)-2,3- BN6628_RS21935 semialdehyde 5'-methylthioadenosine/ ThiO: thiO predicted β semialdehyde BN6628_RS07225 adenosylhomocysteine aminomethylphosphonate glyoxylate acetyl-CoA (5E)-3-oxo- a (1->4)- 1-(5-phospho- - dihydroxy-3- bifunctional 4-hydroxy- 6-cis, 3-oxo- D-gluconate adenosyl-cobyrinate 3-[(5'-methylthio) a supercoiled ABC 3E,5Z-tetradecadienoyl-CoA isobutanoate futalosine (S)-4-amino-5- glu DMK-12 D-threo-isocitrate α D-ribosyl)-AMP methylbutanoate glutamate N- homoserine propanoyl-CoA nucleosidase: propanoyl-CoA phosphate tridecenoyl-CoA a tRNA dodec-5- 6-phosphate a,c-diamide pentyl]malate duplex DNA -D-glucan asp a sugar a sugar 2-oxobutanoate tetrahydrodipicolinate oxopentanoate 1,4-alpha-glucan transporter acetyltransferase/ dehydrogenase: BN6628_RS09220 acyl-CoA thioesterase: acetate--CoA ligase: futalosine hydrolase: phosphate acetyl-CoA C- glutamyl-tRNA enoyl-CoA demethylmenaquinone 6-phosphogluconate cobyric acid NADP-dependent 3-isopropylmalate helicase: bifunctional 2,3-dihydroxy- gln synthase: 2-oxoacid ferredoxin acetyl-CoA C- branching aspartate of a sugar amino-acid BN6628_RS06630 S-ribosyl-L- L-threonine BN6628_RS18880 BN6628_RS09235 BN6628_RS15180 propanoyltransferase: acyltransferase: reductase: methyltransferase: dehydrogenase synthase: isocitrate dehydrogenase: BN6628_RS09300 phosphoribosyl- isovalerate acetolactate BN6628_RS16295 oxidoreductase: acetyl-CoA fermentation to butanoate II Carboxylate Degradation acyltransferase: protein GlgB: ammonia- AMP cyclohydrolase/ dehydratase: synthase, acetyltransferase (2S,4S)-4- homocysteine biosynthesis acyl-CoA thioesterase: BN6628_RS16180 BN6628_RS13930 BN6628_RS06470 BN6628_RS13930 BN6628_RS10370 (decarboxylating): gnd BN6628_RS05890 dehydrogenase: leuB [+ 7 isozymes] a sugar RS18480 a sugar carbamoyl- L-homoserine BN6628_RS16185 pyruvate fermentation to acetate I dehypoxanthine propanoyl 4-cis- an L-glutamyl- BN6628_RS11530 lyase: aspA phosphoribosyl- ilvD large subunit, ArgJ: argJ N-acetyl-L- L-methionine salvage cycle I (bacteria and plants) hydroxy-2,3,4,5- BN6628_RS04515 isobutanoyl-CoA AMP diphosphate hypoxanthine acetyl-CoA acetyl-CoA (3E)-dec-3- D-ribulose BN6628_RS18860 8-(methylthio)- a single phosphate synthase futalosine phosphate undecenoyl-CoA [tRNA Glu ] menaquinol-12 adenosylcobyrate ATP diphosphatase biosynthetic ornithine tetrahydrodipicolinate 2-oxobutanoate acetyl-CoA coenzyme A (3E,5Z)-tetradecadienoate enoyl-CoA 5-phosphate 2-oxoglutarate 2-oxooctanoate stranded DNA starch fumarate 3-methyl-2- small subunit: L-homoserine pyruvate HisIE: type: ilvB 4-hydroxy- oxobutanoate BN6628_RS08335 met homoserine kinase: predicted BN6628_RS00850 tetrahydrodipicolinate acetolactate [+ 2 isozymes] carbamoyl- 2-oxoglutaramate BN6628_RS06635 acetyl-CoA phosphate ABC 1-(5-phospho-β-D-ribosyl)- reductase: synthase, L-homocysteine pyruvate synthase: a 2,3,4-saturated (25S)-3- (2E,4E)- a sugar a sugar 2-isopropylmalate branched-chain- (S)-2-aceto-2- phosphate synthase O-phospho- acetyltransferase: acetyltransferase α 3-oxo-(7Z)- O-ureido-L- 3-octaprenyl-4- 3-[(4'-methylthio) transporter 5-[(5-phosphoribosylamino) BN6628_RS10575 large subunit, BN6628_RS03940 -D-glucopyranose 1-phosphate UTP isovalerate CTP 1,2-diacyl-sn- a [protein]-L-glutamine serotonin oxocholest- coenzyme A a protein DMKH2-13 asp tetradecadienoyl- ethanol (S)-malate gly synthase: amino-acid hydroxybutanoate large subunit: methionine biosynthetic L-homoserine BN6628_RS07215 PlsX: tetradecenoyl-CoA homoserine hydroxybenzoate butyl]malate of a sugar methylideneamino]imidazole- (S)-2,3,4,5- UTP--glucose-1-phosphate acetate--CoA ligase: glycerol 3-phosphate transglutaminase: acetyl-CoA C- 4-en-26-oate acyl-CoA CoA BN6628_RS11690 transaminase: ketol-acid BN6628_RS08340 adenosyltransferase: type: ilvB BN6628_RS16830 phosphatidate GPR endopeptidase: demethylmenaquinone argininosuccinate UbiD family 2,4-dienoyl- 3-isopropylmalate catalase: malate:quinone glycine 4-carboxamide tetrahydrodipicolinate threonine synthase: uridylyltransferase: galU BN6628_RS09235 BN6628_RS11880 acyltransferase: synthetase: 2-isopropylmalate BN6628_RS06645 reductoisomerase: BN6628_RS22105 acetyl-CoA CO cytidylyltransferase: BN6628_RS07755 methyltransferase: synthase: decarboxylase: CoA reductase: dehydrogenase: BN6628_RS14575 oxidoreductase: oxidase predicted 1-(5-phosphoribosyl)-5- carbamoyl L-ornithine 2-oxoglutarate [+ 2 isozymes] BN6628_RS05310 acetoacetyl-CoA pyruvate fermentation 2 UTP--glucose-1-phosphate BN6628_RS16410 [+ 2 isozymes] BN6628_RS13930 (25S)-3- BN6628_RS13935 BN6628_RS10370 BN6628_RS21925 BN6628_RS20130 leuB [+ 2 isozymes] BN6628_RS13610 synthase: leuA branched-chain BN6628_RS06115 a [protein] N 6 -[(5-hydroxy-1H (5Z)- BN6628_RS07240 ThiO: thiO ABC [(5- phosphoribosylamino) phosphate (S)-2-aceto-2- L-cystathionine acetyl phosphate to acetate IV uridylyltransferase: galU isovaleryl-CoA AMP diphosphate a CDP-2,3,4-saturated- acetyl-CoA a peptide a peptide a sugar a sugar amino acid phosphate -indol-3-yl)ethyl]-L-glutamine dodecenoyl-CoA oxocholest-4- canavaninosuccinate (3E)-tetradec- 7-(methylthio)-2- transporter methylideneamino]imidazole-4- (R)-2,3-dihydroxy- hydroxybutanoate thr α diacylglycerol menaquinol-13 2-octaprenylphenol acetaldehyde oxaloacetate glyoxylate (2S)-2- aminotransferase: 4-(methylsulfanyl)-2-oxobutanoate SAM acetyltransferase UDP- -D-glucose en-26-oyl-CoA 3-enoyl-CoA oxoheptanoate of a sugar carboxamide isomerase: hisA 3-methylpentanoate adenosylmethionine L-α-amino-ε- pyruvate isopropylmalate BN6628_RS16090 2-aceto-2-hydroxy- acetate kinase: PlsX: 2,3-dihydroxy-3- decarboxylase: keto-pimelate butanoate (3R)-3- BN6628_RS10660 BN6628_RS16830 phosphoribulosylformimino- 3-isopropylmalate methylvalerate hydroxybutanoyl- a sugar RS12345 a sugar BN6628_RS06010 isomeroreductase: formate C- all-trans- 3-methyl-2- 3-oxo-(11Z)- a monocarboxylic 3-[(3'-methylthio) AICAR-phosphate dehydratase hydro-lyase: ilvD diaminopimelate CoA phosphatidylglycerophosphate isoprimeverose 2-hydroxyisobutyramide glycerol MeOH ferroheme o ornithine adenosylmethionine BN6628_RS06115 acetate acetyltransferase: acetyl phosphate octaprenyl 4-hydroxybenzoate oxobutanoate octadecenoyl-CoA a type IV prepilin a protein a protein acid amide propyl]malate D-ala large subunit: leuC val dehydrogenase: cys (1-octadecenoyl(9Z), 2-palmitoyl) NAD(P)- (S)-3-methyl-2- carbamoyltransferase: decarboxylase: glycine biosynthesis II pflB diphosphate 2-oxoisovalerate acetyl-CoA C- amidase: amidase: 3-isopropylmalate catalase: imidazole glycerol 3-isopropylmalate BN6628_RS02440 (R)-2,3-dihydroxy- 4-hydroxybenzoate alpha-xylosidase: prepilin peptidase: lysyl endopeptidase: metalloprotease: dependent alcohol heme A synthase: glycine oxopentanoate argF BN6628_RS06465 acetate kinase: phosphatidylglycerophosphatase dehydrogenase: acyltransferase: BN6628_RS09590 BN6628_RS09590 dehydrogenase: BN6628_RS14575 a sugar RS24370 a sugar phosphate synthase dehydratase meso- 3-methylpentanoate a [glycine-cleavage octaprenyltransferase: BN6628_RS15070 BN6628_RS05710 BN6628_RS19235 BN6628_RS14445 dehydrogenase: BN6628_RS20135 oxidase branched-chain- BN6628_RS10660 A: BN6628_RS06290 BN6628_RS10010 BN6628_RS13930 leuB subunit HisF: small subunit: leuD 1,2-dihydroxy-5- diaminopimelate 2,3-dihydroxy-3- gly complex H protein] acetyl-CoA formate BN6628_RS10375 a cleaved type [+ 2 isozymes] [+ 2 isozymes] BN6628_RS18080 [+ 2 isozymes] ThiO: thiO amino-acid dAdoMet crotonyl-CoA 3-octaprenyl-4- NADH CO isobutanoyl-CoA palmitoleoyl-CoA acetyl-CoA a peptide a peptide a peptide a peptide a peptide BN6628_RS00845 (methylsulfanyl)pent-1-en-3-one methylvalerate 6 1-oleoyl-2-palmitoyl- α-D-xylopyranose D-glucopyranose 2 IV prepilin 2-hydroxy-2- 6-(methylthio)- diaminopimelate N -lipoyl-L-lysineEnpEP protein: acetate hydroxybenzoate a monocarboxylate L-glyceraldehyde formaldehyde ferroheme a pyruvate 2-isopropylmaleate transaminase: hydro-lyase: ilvD acyl-CoA phosphate phosphatidylglycerol methylpropanoate 2-oxohexanoate predicted imidazole BN6628_RS06645 2-hydroxy-3-keto-5- putrescine decarboxylase: lysA BN6628_RS00370 methylthiopentenyl- (S)-3-methyl-2- dehydrogenase: acetyltransferase ABC glycerol 3-isopropylmalate spermidine synthase: diaminopimelate gcv system: a sugar a sugar branched-chain L-citrulline 1- phosphate oxopentanoate BN6628_RS23750 PlsX: transporter phosphate dehydratase BN6628_RS14395 decarboxylase: lpdA N-acetyl-D-glucosaminyl-N- 3-oxo-(6Z,9Z,12Z,15Z,18Z) 5-cis, 7-trans-3-oxo- 2-methylacetoacetyl- 3-[(7'-methylthio) amino acid phosphatase: branched-chain- CO [+ 2 isozymes] BN6628_RS16830 1-(3-sn-phosphatidyl)- maltohexaose butanoyl-CoA acetyl-CoA 4-guanidinobutyramide an acetyl ester an L-cysteinyl- xylitol propionamide oxaloacetate diacetyl of a sugar synthase large subunit: leuC spermidine BN6628_RS13310 2 acetylmuramoyl-L-alanyl-D-glutamyl- aminotransferase: pyruvate decarboxylation to acetyl CoA sn-glycerol 3-phosphate -tetracosapentaenoyl-CoA tetradecadienoyl-CoA CoA [tRNA Cys ] heptyl]malate subunit argininosuccinate BN6628_RS10705 amino-acid L-tryptophan biosynthesis 6-carboxy-L-lysyl-D-alanine acetyl-CoA C- alpha-glucosidase: acetyl-CoA C- acetyl-CoA acetyl-CoA C- acetylesterase: NAD(P)- 3-isopropylmalate BN6628_RS16090 butanoyl-CoA acetyl phosphate LD-carboxypeptidase: amidase: aminoacyl-tRNA 3-isopropylmalate amidase: predicted HisH: hisH synthase: lys transaminase: phosphatidylglycerophosphatase acyltransferase: BN6628_RS15515 acyltransferase: acetyltransferase: acyltransferase: BN6628_RS18685 dependent alcohol citrate synthase: diacetyl reductase: dehydratase 2-hydroxy-5-(methylsulfanyl)- a [pyruvate dehydrogenase BN6628_RS13815 BN6628_RS09590 hydrolase: dehydrogenase: BN6628_RS09590 ABC BN6628_RS21925 S-methyl-5'-thioadenosine BN6628_RS06645 A: BN6628_RS06290 N-acetyl-D-glucosaminyl-N- BN6628_RS13930 [+ 2 isozymes] BN6628_RS13930 BN6628_RS07215 BN6628_RS13930 [+ 2 isozymes] dehydrogenase: BN6628_RS18865 BN6628_RS16795a sugar a sugar small subunit: leuD ile 3-oxopent-1-enyl 1-phosphate chorismate acetate kinase: 6 pyruvate [+ 2 isozymes] BN6628_RS25250 leuB [+ 2 isozymes] D-erythro- 5'-methylthioadenosine/ E2 protein] N -lipoyl-L-lysine (4Z,7Z,10Z,13Z,16Z)- (3Z,5E)-dodeca- 3-oxohexanoyl- BN6628_RS18080 transporter L-arginino- branched-chain dehydrogenase D-ala acetylmuramoyl-L-alanyl-D- acetyl-CoA D-glucopyranose maltopentaose acetyl-CoA acetyl-CoA propanoyl-CoA acetate an alcohol Cys AICAR imidazole-glycerol- (2R,3S)-3- adenosylhomocysteine BN6628_RS10660 an L-1-phosphatidyl- docosapentaenoyl-CoA 3,5-dienoyl-CoA CoA a tRNA cys 10-(methylthio)- of a sugar succinate 2,3-diketo-5- amino acid anthranilate dihydrolipoyl (acetyl- glutamyl-6-carboxy-L-lysine 4-guanidinobutanoate D-xylopyranose propanoate citrate acetoin phosphate isopropylmalate nucleosidase: sn-glycerol 2-oxodecanoate argininosuccinate methylthiopentyl-1- aminotransferase: synthase: trpE butanoate acetate dehydrogenase: transferring) pyruvate imidazoleglycerol- 3-isopropylmalate BN6628_RS09220 a sugar RS15060 a sugar L-proline biosynthesis I lyase: argH phosphate enolase: BN6628_RS16090 lpdA E1 component phosphate dehydrogenase: L-methionine biosynthesis III BN6628_RS10710 anthranilate subunit UDP-N-acetyl-α-D-muramoyl- 5-amino-4- salicyl-6-hydroxy-2- a [lipoyl-carrier 3-oxo- 3-oxo-4-pregnene- a (2E,4E)- dehydratase HisB: leuB superpathway of L-serine dihydrolipoyl D-alanyl-D-alanine PRPP (+)-7-epi-jasmonoyl-CoA acetyl-CoA maltopentaose (R)-lipoate a tripeptide trans-dienelactone formate CTP an aryl sulfate acetoin ile dehydrogenase: alpha: pdhA L-alanyl-γ-D-glutamyl-L-lysine imidazolecarboxyamide cyclohexene-on-oyl protein]-L-lysine palmitoyl-CoA a protein 20-carboxyl-CoA dienoyl-CoA BN6628_RS00830 (2S)-2-isopropyl- and glycine biosynthesis I Glu arg anthranilate alpha-glucosidase: 5-(methylsulfanyl)-2,3- L-homoserine UDP-N-acetylmuramoyl- adenine acetyl-CoA C- carboxylesterase: lipoate-- acetyl-CoA C- peptidase dienelactone acetyl-CoA C- anaerobic 2,4-dienoyl- a sugar RS12425 a sugar MTR lpdA BN6628_RS15515 trypsin: imidazole acetol- 3-oxosuccinate 3-phospho- glutamate 5-kinase: dioxopentyl 1-phosphate homoserine O- phosphoribosyltransferase: trpD superpathway of acetate tripeptide--D-alanyl- phosphoribosyltransferase: acyltransferase: BN6628_RS04730 protein ligase: acyltransferase: T: pepT hydrolase: acyltransferase: ribonucleoside- sulfatase: CoA reductase: diacetyl reductase: S-methyl-5- utilization and formation a [pyruvate dehydrogenase a [pyruvate dehydrogenase [+ 2 isozymes] 6-hydroxy-2- BN6628_RS21790 BN6628_RS21055 BN6628_RS16795 phosphate D-glyceratephosphoglycerate BN6628_RS10725 acetyltransferase: D- alanine ligase: BN6628_RS06840 BN6628_RS13930 BN6628_RS05835 BN6628_RS13930 a proteinogenic BN6628_RS12620 BN6628_RS13930 triphosphate BN6628_RS07240 γ-L-glutamyl thioribose kinase: N-(5-phosphoribosyl)-anthranilate 6 6 3-oxo-2-(cis-2'-pentenyl)- salicyl alcohol cyclohexen- a [lipoyl-carrier protein]- a dipeptide methylthioribulose E2 protein] N - E2 protein] N -S- BN6628_RS08190 AICAR D-glucopyranose maltotetraose myristoyl-CoA acetyl-CoA a peptide a peptide amino acid histidinol-phosphate dehydrogenase: BN6628_RS19445 α 6 3,22-dioxochol- reductase: nrdD a (3E)-3- a sugar RS17365 a sugar 5-phosphate 1-phosphate BN6628_RS19090 O-acetyl-L- acetate dihydrolipoyl-L-lysine acetyldihydrolipoyl-L-lysine UDP-N-acetyl- -D-muramoyl-L-alanyl- cyclopentane-1-(3-oxobutanoyl)-CoA one-carboxylate N -lipoyl-L-lysine 2-maleylacetate a phenol diacetyl transaminase: BN6628_RS10240 hydrogen sulfide acetate--CoA ligase: γ 4-en-24-oyl-CoA dCTP enoyl-CoA 4-methyl-2- glutamate-5- L-phenylalanine dehydratase: mtnB homoserine phosphoribosylanthranilate -D-glutamyl-L-lysyl-D-alanyl-D-alanine BN6628_RS10470 oxopentanoate 3-phosphooxypyruvate BN6628_RS09235 semialdehyde biosynthesis I O-acetylhomoserine isomerase: BN6628_RS10455 acetate kinase: L-histidinol- BN6628_RS10660 branched-chain- 3-phosphoserine dehydrogenase: aminocarboxypropyltransferase: 1-(o-carboxyphenylamino)-1'- L-4-hydroxyphenylglycine- 3-oxo-2-(cis-2'-pentenyl)- a 7,8-dihydro-8- a (1->4)- 4-trans-3-oxo- (S)-2,3- (indol-3-yl) a (2E,4Z)- a sugar RS09725 a sugar phosphate chorismate lipoate acetyl-CoA maltoheptaose α octanoyl-CoA acetyl-CoA H + malonyl-CoA D-galactopyranose formate UTP methylglyoxal DHAP amino-acid aminotransferase: BN6628_RS10720 5-(methylthio)ribulose 1-phosphate 5-MTR-1-P BN6628_RS20810 deoxyribulose 5'-phosphate D-gluconate L-arginyl-D-4- cyclopentane-1-hexanoyl-CoA oxoguanine in DNA -D-glucan undecenoyl-CoA dihydrodipicolinate acetamide dienoyl-CoA chorismate acetyl-CoA acetyltransferase: alpha-glucosidase: alpha-glucosidase: histidinol- transaminase: BN6628_RS12150 L-glutamate-5- indole-3-glycerol- acetyl phosphate acetyl-CoA oxalate degradation hydroxyphenylglycine-L-seryl- acetyl-CoA C- DNA- acetyl-CoA C- acetyl-CoA C- type III polyketide dipicolinate amidase: anaerobic glyoxalase: 2,4-dienoyl- mutase: aroH lpdA BN6628_RS15515 BN6628_RS15515 galactose oxidase: methylglyoxal phosphatase: BN6628_RS06645 semialdehyde L-homocysteine phosphate synthase: degradation V L 4-hydroxyphenylglycinetrypsin: acyltransferase: formamidopyrimidine acyltransferase: acyltransferase: synthase: synthase subunit B: BN6628_RS09590 ribonucleoside- BN6628_RS13990 CoA reductase: 3-phospho- D-gluconate [+ 2 isozymes] [+ 2 isozymes] BN6628_RS08750 synthase: mgsA predicted BN6628_RS11815 branched-chain bifunctional 3-deoxy-7- BN6628_RS10450 BN6628_RS21790 BN6628_RS13930 glycosylase: mutM BN6628_RS13930 BN6628_RS13930 BN6628_RS11900 BN6628_RS16310 [+ 2 isozymes] triphosphate [+ 7 isozymes] BN6628_RS07240 L-serine 5-methyltetrahydropteroyltriglutamate- gluconokinase: D-4-hydroxyphenylglycine- 3-oxo-2-(cis-2'-pentenyl)- an apurinic site 7,8-dihydro- a (1->4)- 2-trans- 3-oxodecanoyl- ABC histidinol- amino acid phosphoheptulonate phosphate oxalate L-4-hydroxyphenylglycine- D-glucopyranose maltohexaose D-glucopyranose α acetyl-CoA octoketide dipicolinate D-galacto- reductase: nrdD a (3E)-3- a sugar a sugar - homocysteine S- methionine (1S,2R)-1-C-(indol-3- gntK L-seryl-L 4- cyclopentane-1-(3-oxooctanoyl)-CoA within DNA 8-oxoguanine -D-glucan nonenoyl-CoA CoA (indol-3-yl)acetate (R)-lactate methylglyoxal transporter phosphatase: aminotransferase: synthase/ S-methyl-5-thioribose- acetyltransferase PlsX: oxalate L-arginine hexodialdose dUTP enoyl-CoA 1-phosphate methyltransferase: metE synthase: yl)glycerol 3-phosphate gluconokinase: hydroxyphenylglycine of a sugar BN6628_RS00855 BN6628_RS16090 (S)-1-pyrroline- chorismate mutase: BN6628_RS16830 decarboxylase: BN6628_RS16975 isomerase: mtnA methionine metH tryptophan synthase gntK 5-carboxylate BN6628_RS04010 D-gluconate a sugar RS02810 a sugar histidinol leu prephenate synthase: subunit beta: trpB formate 3-oxo-2-(cis-2'-pentenyl)- trans-∆ 2 , cis-∆ 4 - a (2E,4E)- ser pyrroline-5- 6-phosphate O-acetyl-L- acetyl-CoA nicotinate PRPP pyruvate a ribonucleic acid decanoyl-CoA acetyl-CoA GSSH sulfite FMN NAD(P)H H + a kanamycin ribulose pyrazinamide citrate metH tryptophan synthase methanethiol cyclopentane-1-butanoyl-CoA asp fumarate decadienoyl-CoA dienoyl-CoA histidinol carboxylate prephenate homoserine acetyl-CoA C- nicotinate pyruvate synthase: ribonuclease PH: acetyl-CoA C- rhodanese domain- serine subunit alpha: O-acetylhomoserine L-aspartate FMN reductase aminoglycoside 2,4-dienoyl- amidase: 2,4-dienoyl- aconitate dehydrogenase: reductase: dehydratase: S-adenosyl-L-methionine cycle II S-adenosyl-L-methionine cycle I acyltransferase: phosphoribosyltransferase: BN6628_RS03940 BN6628_RS06300 acyltransferase: containing protein: ribulokinase: hydroxymethyltransferase: met BN6628_RS10465 Fatty Acid and Lipid Degradation aminocarboxypropyltransferase: oxidase: nadB (NADPH): ssuE phosphotransferase: CoA reductase: BN6628_RS09590 CoA reductase: hydratase a sugar RS01795 a sugar hisD proC BN6628_RS06640 BN6628_RS13930 BN6628_RS16130 a nucleoside BN6628_RS13930 BN6628_RS14895 BN6628_RS15825 BN6628_RS12155 BN6628_RS20810 a reduced a ribonucleic acid NAD(P) + FMNH BN6628_RS14975 BN6628_RS07240 [+ 2 isozymes] BN6628_RS07240 AcnA: acnA ser 3-oxo-2-(cis-2'-pentenyl)- CO acetyl-CoA 3-oxododecanoyl- succinate 2-iminosuccinate 2 keto- indole NaMN flavodoxin 2 diphosphate thiosulfate glutathione a kanamycin L(or D)-ribulose histidinal serine SAM β acetate met (2E)-dec-2- pyrazine-2- a (2E)-2- uracil degradation pro phenylpyruvate met fatty acid -oxidation I cyclopentane-1-(3-oxohexanoyl)-CoA CoA 3'-phosphate 5-phosphate D-threo-isocitrate hydroxymethyltransferase: methionine enoyl-CoA carboxylate enoyl-CoA a sugar RS04470 a sugar histidinol I (reductive) aromatic amino acid BN6628_RS22290 adenosyltransferase: tryptophan synthase a (3Z)-alk-3- dehydrogenase: uracil aminotransferase: methionine 5-methyltetrahydropteroyltriglutamate- BN6628_RS22105 subunit beta: trpB enoyl-CoA 3-[(3aS,4S,7aS)-7a-methyl- a DNA containing hisD BN6628_RS06255 adenosyltransferase: 3α,7α,12α-trihydroxy-24- 3-oxo-(5Z)- all-trans- an N-acyl-D- phosphoenol gly - homocysteine S- 1,5-dioxo-octahydro-1H coenzyme A MEP CTP an apurinic/ hexanoyl-CoA acetyl-CoA canavaninosuccinate maltose deethylsimazine 3-ethylmalate a double-helix DNA ∆ 3 ∆ 2 an N-formyl-L-methionylaminoacyl-tRNA oxo-5-β-cholestanoyl CoA tetradecenoyl-CoA retinyl palmitate glucosamine pyruvate a sugar RS14670 a sugar methyltransferase: metE BN6628_RS22105 -cis- -trans-enoyl- apyrimidinic site acetyl-CoA C- acetyl-CoA C- phe peptide deformylase: def -inden-4-yl]propanoate 2-C-methyl-D- sterol carrier protein: argininosuccinate carboxylesterase: alpha-glucosidase: N-ethylammeline N-acylglucosamine 3-isopropylmalate DNA helicase his 5,6-dihydrouracil L-alanine trp CoA isomerase: acyl-CoA synthetase: endonuclease pyruvate L-glutamate methionine synthase: metH met SAH erythritol 4-phosphate BN6628_RS07235 acyltransferase: acyltransferase: lyase: argH BN6628_RS04730 BN6628_RS15515 chlorohydrolase: 2-epimerase: dehydrogenase: RecQ: recQ biosynthesis III long-chain fatty BN6628_RS07210 peptide deformylase: 3-[(3aS,4S,7aS)-7a-methyl-BN6628_RS13935 III: nth kinase: pyk biosynthesis III cytidylyltransferase: ispD propanoyl-CoA choloyl-CoA a 3'-terminal a 5'-phospho- BN6628_RS13930 BN6628_RS13930 fumarate L-canavanine palmitate a retinol [+ 2 isozymes] BN6628_RS10635 BN6628_RS18735 leuB [+ 5 isozymes] hydantoinase 5'-methylthioadenosine/ acid--CoA ligase: BN6628_RS20955 1,5-dioxo-octahydro-1H- 4-(cytidine 5'-diphospho) 3-oxooctanoyl- (3Z)-dodec- a sugar RS01715 a sugar subunit beta: L-homocysteine SAM a (2E)-2- unsaturated sugar [DNA] acetyl-CoA an N-acyl-D- an unwound double- 2-oxoglutarate cys adenosylhomocysteine BN6628_RS07225 formate a L-methionylaminoacyl-tRNA inden-4-yl]propanoyl-CoA -2-C-methyl-D-erythritol CoA 3-enoyl-CoA D-glucopyranose N-ethylammeline 2-oxovalerate pyruvate BN6628_RS12700 5-methyltetrahydropteroyltriglutamate- enoyl-CoA enoyl-CoA mannosamine stranded DNA NADP-specific cysteine desulfurase: nucleosidase: a 2,3,4-saturated acyl-CoA BN6628_RS06940 - homocysteine S- BN6628_RS09220 coenzyme A hydratase: 3-ureidopropanoate glutamate methyltransferase: metE fatty acid synthetase: acyl-CoA BN6628_RS07210 a sugar RS24095 a sugar dehydrogenase: [+ 3 isozymes] BN6628_RS13935 dehydrogenase: a 2,3,4- a 2-oxo 13-sophorosyloxydocosanoate 1-18:1-2- 7,8- 3-oxo- (-)-methyl a (1->4)-β-D-xylan a large- D-ribulose methionine synthase: metH [DNA] maltotriose FMNH NADP + β-D-allopyranose acetamide 2-deoxy-D-ribose BN6628_RS22870 ala L-homocysteine S-ribosyl-L-homocysteine BN6628_RS07220 saturated (3R)-3- carboxylate 6',6''-diacetate 2 oligosaccharide branched glucan 5-phosphate lysophosphatidylethanolamine dihydromonapterin alpha-glucosidase: myristoyl-CoA jasmonate Glu adenosylhomocysteinase: [+ 2 isozymes] a 2,3,4- hydroxyacyl-CoA 2-oxoacid ferredoxin acetylesterase: exodeoxyribonuclease lysophospholipase: dihydroneopterin acetyl-CoA C- carboxylesterase: FMN reductase ribulose-phosphate amidase: a 2,3,4-saturated oxidoreductase: BN6628_RS15515 acyltransferase: D-ribose pyranase: beta-xylosidase: pullulanase: ribokinase: H + RS22240 H + BN6628_RS08155 saturated (3S)-3- β BN6628_RS18685β III: xth BN6628_RS03365 aldolase: folB BN6628_RS04730 (NADPH): ssuE 3-epimerase: BN6628_RS13085 fatty acyl CoA BN6628_RS16185 13-[O(2')- -D-glucopyranosyl- -D- a 2'- sn-glycero-3- 6-(hydroxymethyl) [+ 2 isozymes] BN6628_RS13930 BN6628_RS14675 BN6628_RS04445 BN6628_RS15125 rbsK β-alanine SAH hydroxyacyl-CoA a reduced oleate glycolaldehyde MeOH (-)-jasmonate H + NADPH FMN BN6628_RS09425 [+ 2 isozymes] acetate glucopyranosyloxy]docosanoate deoxyribonucleoside [DNA] phosphoethanolamine -7,8-dihydropterin a long-linear H + ferredoxin [iron- CO an acyl-CoA O(6'')-acetate 5'-monophosphate D-glucopyranose maltose acetyl-CoA lauroyl-CoA β-D-allofuranose β-D-xylopyranose D-xylulose 2-deoxy-D-ribose 2 α-D-glucan acetate sulfur] cluster 5-phosphate 5-phosphate H + RS10805 H +

a 2,3,4-saturated a 2,3,4-saturated C1 Compound Utilization and Assimilation acetyl-CoA C- a single- a 1-acyl-sn-glycero- an all-trans 3-oxo-(5Z)- dCMP 6,7-dimethyl-8-(1- D-ribose 5- fatty acyl CoA 3-oxoacyl-CoA adenosylcobinamide-GDP α-ribazole a 1,3-β-D-glucan hydrogencarbonate H + (S)-citramalate a chitodextrin acrylamide D-glucopyranose acyltransferase: stranded RNA 3-phosphocholine -retinyl ester dodecenoyl-CoA D-ribityl)lumazine a protein phosphate predicted ABC 1,3--beta-D-glucan 3- formaldehyde oxidation BN6628_RS13930 adenosylcobinamide-GDP polyribonucleotide lysophospholipase: carbonic anhydrase: carboxylesterase: acetyl-CoA C- 5'-deoxynucleotidase: riboflavin synthase: citramalate chitinase: ribose-5-phosphate amidase: (2-aminoethyl)xylose transporter of (2-aminoethyl) formate assimilation into 5,10- formaldehyde glucanohydrolase: endopeptidase VII (THF pathway) ribazoletransferase: cobS nucleotidyltransferase: pnp BN6628_RS03365 BN6628_RS11125 BN6628_RS04730 acyltransferase: BN6628_RS18830 BN6628_RS10160 synthase: BN6628_RS07490 isomerase RpiA: BN6628_RS09590 isomerase: phosphonate (2-aminoethyl) phosphonate methylenetetrahydrofolate oxidation II BN6628_RS12755 La: lon a nucleoside a single- sn-glycero-3- a carboxylate H O CO a fatty acid all-trans-retinol BN6628_RS13930 riboflavin ARP BN6628_RS17585 [+ 3 isozymes] BN6628_RS16935 [+ 2 isozymes] xylA phosphonate 2 2 (3Z)-dec-3- 2'-deoxycytidine formaldehyde (glutathione-dependent) GMP adenosylcobalamin diphosphate stranded RNA D-glucopyranose a 1,3-β-D-glucan phosphocholine acetyl-CoA acetate pyruvate N,N'- a peptide a peptide D-ribulose formate enoyl-CoA keto-D-fructose formaldehyde acetyl-CoA diacetylchitobiose 5-phosphate acrylate

a 5,10- an N 10 - α α β β methylenetetrahydrofolate S-(hydroxymethyl) a [glycine-cleavage 3 ,7 -dihydroxy- 13-[O(2')- -D-glucopyranosyl- -D- D-sedoheptulose D-glyceraldehyde a sophorosyloxyfatty methyl (indol- a dipetide with an N- dUMP N-acetyl-D- formyltetrahydrofolate 24-oxo-5β- glucopyranosyloxy]docosanoate methylsalicylate carbonic acid xylan D-ribulose N-ethylglycine bifunctional glutathione SAM complex H protein] a sulfurated [sulfur carrier] 7-phosphate 3-phosphate acid O(6'')-acetate 3-yl)acetate terminal L-aspartate mannosamine sarcosine bifunctional 6 cholestanoyl CoA O(6'')-acetate glycine methylenetetrahydrofolate glutathione- N -octanoyl-L-lysine acetylesterase: carboxylesterase: dipeptidase: 5'-deoxynucleotidase: carboxylesterase: carbonic anhydrase: N-acylglucosamine glycine methylenetetrahydrofolate lipoyl sterol carrier protein: acetylesterase: transketolase: tkt alpha-xylosidase: ribulokinase: oxidase dehydrogenase/ dependent BN6628_RS18685 BN6628_RS04730 BN6628_RS16195 BN6628_RS18830 BN6628_RS04730 BN6628_RS11125 2-epimerase: oxidase dehydrogenase/ synthase: lipA a [glycine-cleavage BN6628_RS07235 BN6628_RS18685 D-xylulose D-ribose 5- a sophorosyloxyfatty BN6628_RS15070 BN6628_RS15825 ThiO: thiO methenyltetrahydrofolate formaldehyde an unsulfurated chenodeoxycholoyl- acetate MeOH (indol-3-yl)acetate a proteinogenic asp MeOH salicylate CO H O BN6628_RS18735 ThiO: thiO methenyltetrahydrofolate 5'-deoxyadenosine met complex H protein] propanoyl-CoA acetate sophorosyloxydocosanoate 5-phosphate phosphate acid 2'-deoxyuridine 2 2 N-acetyl-D- cyclohydrolase FolD: dehydrogenase: [sulfur carrier] CoA amino acid α-D-xylopyranose methylamine glyoxylate D-ribulose ethylamine glyoxylate cyclohydrolase FolD: N 6 -lipoyl-L-lysine glucosamine BN6628_RS09910 BN6628_RS24500 5-phosphate BN6628_RS09910 a 5,10- a 5,10- S-formylglutathione β methenyltetrahydrofolate 5,10-methylene- 3-methyl-2- a 5S rRNA a -D- a sophorosyloxyfatty all-trans- D-erythrose D-xylulose UTP dTMP N-acetyl-β-D- uridine methenyltetrahydrofolate a sialyloligosaccharide fructofuranoside acetylxylan FMNH NAD + lichenan pullulan bifunctional tetrahydromethanopterin oxobutanoate precursor acid 6',6''-diacetate retinyl palmitate 4-phosphate 5-phosphate nucleoside triphosphate 2 mannosamine bifunctional reductive monocarboxylic acid cycle 3-methyl-2-oxobutanoate exo-alpha-sialidase: ribonuclease beta-fructosidase: acetylesterase: carboxylesterase: acetyl xylan esterase: FMN reductase 5'-deoxynucleotidase: N-acylglucosamine uridine kinase: methylenetetrahydrofolate transketolase: tkt pyrophosphohydrolase: licheninase: pullulanase: methylenetetrahydrofolate hydroxymethyltransferase: BN6628_RS18505 M5: rnmV BN6628_RS06205 BN6628_RS18685 BN6628_RS04730 BN6628_RS18220 (NADPH): ssuE BN6628_RS18830 2-epimerase: BN6628_RS01575 dehydrogenase/ BN6628_RS25275 BN6628_RS08050 dehydrogenase/ panB N-acetylneuraminate an oligosaccharide a double-stranded a glycoside β-D-fructofuranose a sophorosyloxyfatty D-glyceraldehyde BN6628_RS15125 methenyltetrahydrofolate formate acetyl-CoA a mature 5S-rRNA acetate palmitate all-trans-retinol F6P acetate xylan H + NADH FMN BN6628_RS18735 methenyltetrahydrofolate oligonucleotide acid O(6'')-acetate 3-phosphate UMP thymidine UMP cyclohydrolase FolD: THMPT 2-dehydropantoate GlcNAc a short glucan maltotriose BN6628_RS09910 cyclohydrolase FolD: BN6628_RS09910 formate C- an N 10 - a 5,10- acetyltransferase: pyruvate synthase: formyltetrahydrofolate methylenetetrahydrofolate pflB BN6628_RS03940 formyltetrahydrofolate deformylase: purU pyruvate formate

an amino an amino an amino acid acid acid D-fructose D-mannose a β- a β- molybdate an L-sorbose 1-phosphate a branched- glutathione a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate an amino an amino an amino an amino a carbohydrate 1-phosphate 6-phosphate glucoside 6- glucoside 6- α-L- phosphate cis-vaccenoyl-CoA cis-vaccenoyl-CoA putrescine methyl D-fructose D-glucose 6- D-glucose 6- D-glucose 6- D-mannose D-fructose 1-phosphate chain Ni 2+ an a sugar 6- a sugar 6- a sugar 6- a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate an aromatic acid acid acid acid molybdate bacitracin ammonium ammonium a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate D-galactose bacitracin a dipeptide a dipeptide a dipeptide phosphate phosphate arabinopyranose phosphate a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA spermidine ammonium D-galactose 1-phosphate phosphate phosphate phosphate 6-phosphate D-mannose 6-phosphate amino acid an oligopeptide oligopeptide phosphate phosphate phosphate carboxylate predicted predicted predicted predicted predicted predicted predicted predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC ABC ABC ABC ABC predicted ABC PEP-driven PEP-driven ABC RS19035 RS15670 RS04275 RS12340 RS12420 RS15795 RS18475 RS17360 RS01545 RS07545 transporter of RS13055 RS09575 transporter of RS17240 RS15585 transporter of RS19810 RS21220 RS18535 transporter of transporter of transporter of transporter of RS09730 RS01800 RS01720 RS09490 RS14820 RS18340 RS04475 transporter of RS03175 RS11855 RS11155 RS13735 transporter RS15005 transporter RS20975 RS13950 transporter RS04710 RS14715 ModA transporter RS19300 PstB RS03770 RS11565 RS13935 RS07225 RS01000 RS01220 RS17610 RS14605 RS15055 RS04555 RS03540 RS01605 transporter of RS24090 RS01310 RS10895 RS10885 transporter RS20405 RS15915 RS07070 RS20970 RS03705 transporter RS20400 RS01200 RS14805 RS04225 RS24925 RS02755 RS22710 RS08145 RS03710 RS12480 RS15910 transporter a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate of an of an of an of molybdate a carbohydrate of D-fructose of D-mannose of glutathione amino acid amino acid amino acid cis-vaccenate cis-vaccenate ammonium ammonium a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid

α-L- L-sorbose a branched- 2+ a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate an amino an amino an amino an amino an amino an amino an amino a β-glucoside a β-glucoside putrescine a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate methyl D-galactose D-fructose D-fructose D-glucose D-glucose D-glucose D-mannose D-mannose Ni an a sugar a sugar a sugar an aromatic molybdate molybdate arabinopyranose phosphate bacitracin D-fructose bacitracin chain a dipeptide a dipeptide a dipeptide glutathione acid acid acid acid acid acid acid spermidine ammonium D-galactose an oligopeptide oligopeptide carboxylate phosphate D-mannose amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.