STATE HIGHER EDUCATION PLAN (2015-16)

KNOWLEDGE CONSORTIUM OF EDUCATION DEPARTMENT Table of Contents

Chapter Chapter Name Page No. No.  Abbreviations -

1 Introduction 1

2 Background 2

3 Concern Strategy And Outcome 5

4 Infrastructure Grants To Colleges 11

5 Research, Innovation And Quality Improvement 13

 Annexures 14-316

1. Demographic Characteristics of Gujarat 14

2. Meritorious fellows 27 3. Basic of Colleges Details for Component -7: Infrastructure 28 Grant to Colleges 4. Basic Details of Universities for Component -8: Research, 31 Innnovation & Quality Improvement 5. Nanoscienece and Advanced Materials Research 33 6. Interdisciplinary Research in Life Scienece and Intergrated 58 Teaching in Cell and Molecular Biology 7. Climate Change Impacts Studies on Shoreline Diversity of 83 Gujarat 8. Post Doctoral Centre in Chemistry Department 165

9. Center of Excellence for Drug Development Technology 181

10. Technologies for Affordable Healthcare 229

11. Interdisciplinary Studies in Social Sciences and Humanities 236

12. Research Centre for Area Studies 266

13. Detail Presentations by the Proposed Universities 279

ABBREVIATION

RUSA Rashtriya Ucchatar Shiksha Abhiyan

NAAC National Assessment and Accreditation Council

GERs Gross Enrolment Ratios

SC Scheduled Castes

ST Scheduled Tribes

IIMA Indian Institute of Management

IRMA Institute of Rural Management Anand

NIT National Institute of Technology

NID National Institute of Design

IIT Indian Institute of Technology

CEPT Centre for Environmental Planning and Technology University

NCC National Cadet Corps

NSS National Service Scheme

SCOPE Society for Creation of Opportunity through Proficiency in English

KCG Knowledge Consortium of Gujarat

API Academic Performance Index

ERP Enterprise resource planning

ODOLE On-demand on-line examination system

ICT Information and Communication Technology

IT Information Technology

NRI Non Residential Indian

SEZ Special Educational Zone

MHRD Ministry of Human Resource Development

NET National Eligibility Test

SLET State lectureship Eligibility Test

UGC University Grant Commission

GV Gram Vidhyapeeth

CBCS Choice Based Credit System IDP Institutional Development plan

SKY Sagar Khedu Yojana

PG Post Graduate

UG Under Graduate

EBB Educationally Backward Block

BISAG Bhaskaracharya Institute for Space Applications and Geo-informatics

MOOCs Massive Open Online Course

IITRAM Institute of Infrastructure Technology Research and Management

LAN Local Area Network

PPP Public Private Partnership

GIA Grant in Aid

GPSC Gujarat Public Service Commission

ISBN International Standard Book Number

CEO Chief Executive Officer

PAR Psychological Assessment Resources

FAQ Frequently asked questions

AMC Ahmadabad Municipal Cooperation

O & M Operations & Maintenance

CCTV Closed-circuit television

MoU Memorandum of Understanding

LOOC Learning Outcome Oriented Curriculum

CCDC Curriculum & Content Development Cell

NBA National Board of Accreditation

IQAC Internal Quality Assurance Cell

DAIICT Dhirubhai Ambani Institute of Information and Communication Technology

PRL Physical Research Laboratory

ATIRA Ahmedabad Textile Industry's Research Association

GIDC Gujarat Industrial Development Corporation

CSR Corporate Social Responsibility

SFI Self Finance institutions OBC Other Backward Castes

OJAS Online Job Application System

OMR Optical mark recognition

ASC Academic Staff Colleges

GKS Gujarat knowledge Society

UK United Kingdom

ICAI Institute of Chartered Accountants of

CAM Centre for Academic Management

MASS Monitoring, Audit & Students Support

AAA Academic and Administrative Audit

EMIS Education Management Information System

BCA Bachelor of Computer application

MCA Masters of Computer application

KYC Know your customer

IWDMS Integrated Workflow & Document Management System

LCD Liquid-crystal display

RFID Radio-frequency identification

Gujarat State Higher Education Plan 2015-16

CHAPTER-1: INTRODUCTION

MISSION

Gujarat has continued to enhance its reputation as a pioneer in introducing new educational initiatives, which have not only improved the quality of higher education in the state, but also served as a model for replication in other parts of the country. Knowledge has long been recognized as a key source of economic growth and a valuable asset that ought to be suitably leveraged by Governments across the world, especially now, in the era of globalization. The continued mission of the Government of Gujarat is to ensure that a greater proportion of the state’s youth population is able to avail access to good quality higher education.

VISION

For a high-growth economy like Gujarat, built on a thriving agriculture sector and a vibrant industrial base, the knowledge sector is to undoubtedly play a key role in the state’s future growth trajectory. The growth of the future economy will be highly dependent on invention, innovation, ideas and knowledge, the flourishing of which is grossly contingent upon higher education and research. Therefore, with the fact that higher education, skill development and creative thinking can be an economy’s global opportunity, Government of Gujarat aims to ensure that a massive number of youth, who are the highly enthusiastic as well as promising section of the population, get good quality higher education. The youth is the main target group and the opportunities of higher education must reach them in order to make them competitive human resource, to widen their vision, to give them the ability to explore multiple avenues, and to open up innumerable opportunities for their development.

GOALS

To fully explore it’s potential of becoming an educational hub in the near future, and in order to utilize the vibrant economic environment efficiently, there is a need to enhance the quality of education by mobilizing the resources in favour of increasing accessibility, equity and excellence and a new framework for measuring outcomes along the lines of good quality of life is proposed. It is proposed that the underlying goal of education should be to enhance the quality of life of students with disabilities by more emphasis on academic achievement, should guide the curriculum and all modern assessment measures. Not a replacement for our existing curriculum, these programs will represent an option for students whose goals are to enter fields with strong employment demand but also with high attrition rates, especially among those groups who have historically not fared well in existing programs.

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CHAPTER – 2: BACKGROUND

DEMOGRAPHIC PROFILE

During the last decade, Gujarat has shown some improvement in its demographic indicators. The decadal growth rate of population has decreased from 22.48 percent during 1991-2001 to 19.28 percent during 2001-2011 Annexure-1 (Table-1). The total literacy rate has increased from 69.14 (2001) to 79.31 percent (2011): The percentage of male workers has increased from 78.03 (2001) to 82.22 percent (2011) and the percentage of marginal workers has decreased from 20.10 percent to 17.78 percent during the period. The proportion of workers in agriculture has decreased from 52.04 percent (2001) to 49.61 percent (2011). Degree of urbanization has increased from 37.75 percent (2001) to 45.28 percent (2011). However the sex ratio has decreased from 920 to 919 from 2001 to 2011. The work participation of females has decreased by 5 percent during the decade. Although the child sex ratio has increased from 883 to 886 during the period. At the district level (Table -2), and Ahmadabad are densely populated and the highly urbanized districts (Table -6). The sex ratio is favorable in Tapi and Dang districts, but highly adverse in Surat, Ahmedabad and Kachchh. The percentage of scheduled caste population (Table -3) is high in Kachchh, Ahmedabad, Banaskantha and Surendranagar. The scheduled tribe population accounts for greater than 70 percent in Dang, Tapi, Narmada and Dahod districts and around 52 percent in district. About 23 districts have literacy rate of above 70 percent. Among them, female literacy rate is greater than 70 percent only in 11 districts (Table -4). The total work participation rate varies between 35 to 56 percent across the state (Table -5) while the female work participation rate varies between 12 to 50percent. Four districts namely Narmada, Dang and Dahod have more than 80 percent of the workers engaged in agriculture activity. In districts such as Banaskantha, Patan, Sabarkantha, Surendranagar, , Amreli, , Panchmahanl, Tapi, the proportion of workers in agriculture varies between 60 to 80 percent. These districts have the highest concentration of rural population (Table -6).

HIGHER EDUCATION PROFILE

The status of Higher Education in a region is reflected from the Gross Enrolment Ratios (GERs). Over the years, the gross enrolment in Gujarat has increased (Fig.-1). Particularly, during 2000's, there has been a sharp increase in enrolment in higher education. During this period, the number of higher educational institutions for degree (undergraduate and 'postgraduate levels) and professional courses has increased (Table -11) associated with influx of private institutions. Taking into consideration the period from 1960- 61 to 2014-15, the decrease in the gap between the gross enrolment of boys and girls (Fig. 2) is impressive from the perspective of gender equity in the higher education sector. As far as Higher Education in the state is concerned the girls have outnumbered boys students both at Under graduate and post graduate level specially in the field of Arts, Education and Medical. (Table-8). This trends are the evidence that the Gender Equality in Higher Education has increased considerably. As far as category wise

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gross enrolment of students is concerned in the state. The gross enrolment of SC students is highest in Sabarkatha, Banaskatha and Junagadh. The gross enrolement of ST students is highest in Dang, Narmada & Tapi ( Table -9). Some districts of the state shows considerable progress as far as gross enrolment of both male and female students is concern. In districts like Ahemdabad the gross enrolment of students (male & female) is more followed by & Surat (Table-10)

SWOT ANALYSIS

KEY STRENGTH

A. After the economic reforms of 1991, Gujarat has emerged strongly as an industrial hub. The state is the favoured investment destination of domestic as well as foreign companies. It is also home to some world renowned institutes in management, engineering and design in the public sector as well as in the private sector. Some of them are Indian Institute of Management Ahmedabad (IIMA), NIRMA, Institute of Rural Management Anand (IRMA), National Institute of Technology (NIT), National Institute of Design (NID), Indian- Institute of Technology (HT) and Centre for Environmental Planning and Technology (CEPT). Its 1600 km coastal line offers numerous opportunities for international linkages, including industrial, educational and others: B. Due to its higher level of economic growth with developed infrastructure, growing business units and medical facilities, the state is attracting population from all over the country for employment in various sectors. This will not only supply additional number of students from different states for higher education, but the sharing of culture and knowledge will support the enhancement of higher educational quality. C. Gujarat is known for women empowerment and women security as eve-teasing and other crimes against women are less as compared to other states. This enables women to explore more opportunities for higher learning.

WEAKNESS

A. Agricultural workers comprise about half of the total workforce in the state; that is a rural activity. Also, the state contains the around 15 percent of tribal population. Low level of skill, low income and remoteness of villagers in general and tribals in particular restricts the accessibility to higher education. B. The spread of population in the state is highly uneven. The establishment of higher educational institution in the less concentrated region is a costly affair. The distance of higher education institutes from the place of residence and the problems of commuting (especially for the girl students) decreases their chances of being enrolled for higher education. This increases the gender gap in higher education particularly in the courses. C. There has been a rapid growth of higher educational institutions especially in the private sector. The private sector is generally profit oriented. In order to attract the maximum number of students, they

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develop a well-equipped infrastructure at the cost of the quality of education. As a result, the overall quality of higher education suffers.

OPPORTUNITIES

Gujarat has a good potential to emerge as an educational hub in the near future since industrialization has taken place which leads to a demand for more skilled resources. If resources are mobilized for the enhancement of quality of higher education, Gujarat will also emerge as a hub of better human resources. Further, the Sardar Sarovar Narmada Linkage Project has resulted in availability of water supply in most of the villages of the state. This increases the scope of higher education in agricultural technology and related streams.

THREATS

A. On the one hand the education level of female population as well as the overall population in general has increased indicating more awareness among the society. On the other hand, the poor sex ratio particularly the poor child sex ratio is indicates that social evils still exist in the society. It is now imperative that the growth rate achieved by the state should be transformed into the development of the society. It is necessary that the education should not only be growth oriented but it should also lead to development of society. Otherwise it will create a threat for sustainable growth. B. In conclusion, it can be said that the Guajarat is a state endowed with a vibrant pool of entrepreneurial talent, associated with a well-developed infrastructure and communication network. Also, it has the potential to emerge as an educational hub. In order to exploit the vibrant economic environment efficiently, there is a need to enhance the quality of higher education by mobilizing the resources in favour of increasing accessibility, equity and excellence.

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CHAPTER-3 CONCERN, STRATEGY AND OUTCOME

VISION

The SHEP of Gujarat aims to,

1. Maximize the human potential 2. Hone the skills, capability and attitudes of the students that will make our economy prosperous and economically competitive. 3. Eliminate poverty by using quality education as a tool and, 4. Stimulate intellectual curiosity, which will serve as a lifelong motivator for continued learning.

CURRENT CONCERNS

Last few years have seen a rapid growth of higher education sector in Gujarat. Over last 10 years, the number of Universities and research institutes in the State have grown from 35 to 83 (2006-2015), number of students enrolled in higher education sector reached 14,42,224. Although, the State is currently poised to become one of the academic leaders in the country, such a rapid growth has also flagged some new issues and highlighted some of the existing problems like absence of high quality and world class teachers, need to rapidly improve the syllabi of our Universities, lack of focus on improving employability of the students, issues like personality development and confidence enhancement of students, etc. Considering the fast pace of global developments in higher education, there is a need to quickly address some of the following issues-

A. Enhanced focus on Gujarat-specific research issues- Our Universities should actively work with the Industry and Government to look into some of the Gujarat specific issues like nutrition, quality of delivery of health and education services, water conservation and its quality, quality of -sanitation in rural area, dry land agriculture, protected cultivation, environment, urbanization, etc. with the aim of finding lasting solutions.

To illustrate this issue further, IIT, has been asked by Education Department to develop high quality toilets for the schools which should meet following criteria- a. Low water consumption- within the limit of 250 ml per use, b. Low maintenance and high normal cleanliness; and c. Simple design so that it is easy to install. Similarly, other Universities should take up few themes for focused, multidisciplinary research.

B. High level of absenteeism in colleges and universities- There are reports that large number of faculty, especially in the remote affiliated colleges do not take classes regularly, do not prepare well

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and many are seen visiting Gandhinagar without any leave to pursue their personal agenda. One option can be to compulsorily install biometric based attendance system. C. Poor awareness level of lecturers- This is a major problem, specially in the affiliated colleges. UGC has specified a new ACR system called Academic Performance Indicator (API). This should be followed and enforced by the Universities for confirmations, promotions and future funding. D. Outdated syllabus- The syllabus of many courses are not revised regularly and, as a result, they do not take into account the current industry requirements or aspirations of the students. Students and faculty, both are happy with this state of affairs, as such outdated courses do not involve much hard work. An option could be to insist that syllabus of every course must be revised every 5 years and should be done in consultation with industry and potential employers and their views must not be ignored. Technical education system in Germany follows this pattern where industry decides the course and Institutes are supposed to follow them so that the students are immediately employable. E. Poor Employability of students- various studies have concluded that over 90% of our graduates are un-employable as they do not acquire useful and marketable skills. Today, when We are planning to enroll over 3 lakh students by 2017, there is a need that at least 75% of these are immediately employable (rest will opt for higher studies or self-employment). A suggestion can also be made that all students should be encouraged to join any one skill based additional activity like National Cadet Corps (NCC), National Service Scheme (NSS), Society for Creation of Opportunity through Proficiency in English (SCOPE), or any other vocational skill. Participation in such activities should be given some credit. Another suggestion can be to sincerely implement Choice Based Credit System in all Universities. F. Affordability of self-financed courses- Private universities has a potential to give a healthy challenge to the publicly funded universities. However, their steep fees are not affordable to a large majority in the state. State Government has implemented scholarship schemes like CMSS (Chief Minister's Merit-cum-Means Scholarships) in which so far 2538 students(as on 18/12/2015) have received scholarship, in addition to that the the government has also initiated the MYSY (Mukhyamantri Yuvan Swavalamban Yojna) under which 8529 students(as on 07/01/2016) have received financial assistance from the State Government.

It can be suggested that the new self-financed Universities and colleges to be set up must create a sizeable corpus. For supporting poor and meritorious students. They can seek donations, earmark some of the existing revenue, etc. for this corpus. State Government is willing to facilitate their applications for suitable Income Tax rebates.

The present proposal to strengthen wider academic networking of Universities in Gujarat is aimed to partially address some of the issues mentioned above

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IMPLEMENTATION STRATEGY

The SHEP of Gujarat will focus largely on quality teaching for remunerative employment, 50% increase in GER and Equity. Considering the objectives of the RUSA (Rashtriya Ucchatar Shiksha Abhiyan) and the core reforms, which are expected from the participating States and Institutions, the implementation strategy will incorporate the followings-

A. Participating institutions must commit to the academic reforms including whole hearted implementation of Choice Based Credit System, mechanize transfer credit from one University to another, including cross-credit system where a student can earn part of the credit from another University, and full transparency in the financial matters. For this purpose, participating institutions are expected to follow e-tendering system and complete disclosure of expenditure and progress of Schemes on their websites. In addition to it, every participating institution must give a road map for achieving the measurable outcomes mentioned in this Chapter. B. Every participating institution will obtain accreditation from NAAC (National Assessment and Accreditation Council), In addition to it, the Gujarat version called Academic and Administrative Audit will be applied every second year and the scores will be uploaded on Knowledge Consortium of Gujarat (KCG) website. KCG will also try to grade every faculty on the basis of their Academic Performance Index (API) score and the information will be appropriately posted on KCG website. Participating Government run Colleges will be managed by independent Governing Boards, which will have adequate powers in financial and disciplinary matters. Members of the proposed Governing Boards will be drawn from local community, industries and retired academicians of repute, C. Every participating institution must agree to use a common Enterprise Resource Planning (ERP) system through which the applications for admission will be received, fees will be paid by the students, attendance of students and staff will be tracked through a biometric system and the manual attendance system will be abolished, students' academic performance will be tracked through the ERP System and will also be linked with the website,' and internship and employment record will also be tracked through such ERP System. In order to reduce the academic workload of the faculty, every institution will set up On-Demand On-Line Examination System (ODOLE), which will be networked into a state-wide system to be used for other examinations as well. D. In order to address the equity and access concerns, two new Universities (Bhakt Kavi Narshingh Mehta University & Shree Govind Guru University) is established by the State Government in Junagadh & Godhra districts. In addition to that, Marine University, Textile University & Skill Univeristy is also proposed to be established by the Government in short time. There will be heavy emphasis on Information and Communication Technology (ICT) to reach the remotely located students. Libraries will have pre-loaded notebook computers in adequate numbers which will be issued to the students and mini text books will be set up in remote villages. Students coming from disadvantaged groups and remote villages will be offered a 4-weeks' long foundation course in every University. The intake capacity of every Government run University and College will be adequately increased through careful debottlenecking. Outreach of off-campus courses being run by State's Open

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University will be increased along with starting Satcom based evening courses and offering Massive On-line Open Courses through a Virtual UG College for the working and out of college students. More girls' hostels will be constructed in Universities and Colleges catering to the areas having low gender parity index. E. The academic and research excellence will be addressed by organizing long term pre-service and in- service training, setting up specialized centers in the new Universities which will address the specific concerns of the area, few post-doctoral scholarships will be offered to the meritorious faculty members who have potential to grow, and reputed NRI faculty will be invited for short duration to hold 2-3 weeks' workshops on specific themes and with a view to improve the capability of the faculty. F. Students' personality development initiatives like students' clubs, systematic sports activities, and single-credit certificate courses developed by industry, inter-college competitions, English language courses and job-oriented coaching classes will be supported. Students will also be encouraged to bring their grievances and views about the skill sets of their faculty into the Project design in coming years. G. Private sector will play a significant role in achieving the Project goals. It is planned to set up at least 9 new private Universities are established after 2012 under the Gujarat Private Universities Act. It is proposed to develop Special Education Zones in some of the towns having large catchment area where a mega educational zone will be developed with hostels, staff residences, sports area, shopping and entertainment area, common library and wi-fi facility, etc. Interested private sector institutions will be allotted required land for setting up their academic facility. In this way, the facility can become functional in shortest possible time and at a low cost. The Special Educational Zone (SEZ) will take care of infrastructure related legal formalities which will spare considerable hassles for the private education provider. Local community will be encouraged to set up boys hostels as per pre-defined norms and terms, and job-oriented coaching classes and vocational training courses will be run in the Universities and colleges by following a variant of Gujarat Knowledge Society model. H. Participating Universities will have to use this opportunity to strengthen their accounts and audit related controls by bringing in the best professionally managed private sector practices, putting into a place the mechanism for cross registration of students so that the strength of various sectoral universities is harnessed for the benefits of students, de-bottleneck their infrastructure to increase the intake of students and the newly established Universities must undergo a process of external evaluation of their practices, procedures, courses and support to the students as part of the preparatory activities. I. Considering the huge data requirement which is being considered by the Ministry of Human Resource Development (MHRD and the time required for selecting an agency to conduct a meaningful baseline study, it is proposed to submit a SHEP for the fourth year of the RUSA

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MEASURABLE OUTCOMES AND OTHER REQUIREMENTS FROM PARTICIPATING UNIVERSITIES

The State Plan aims at achieving following outcomes in next five years. IDP of every participating University and Colleges will incorporate these parameters-

Sr. Outcome Goal How will it be measured No. Increase in attendance of 1 5% Biometric based attendance system. students and faculty % of students passing NET/SLET, NAAC/AAA score, 2 Better teaching & research students employability index, and research citation

index, average API score of faculty CBSC implementation score, cross credit. score of Better academic support to 3 individual Universities, % of syllabus revised in last 5 students years

4 Improvement in GER 5% Student enrolment data

5 Gender parity index 0.9 Student enrolment data

6 Average enrolment per College 900 Student enrolment data

Increase in average number of 7 students per govt. supported 25% Student enrolment data college 15% of 8 Enrolment in science stream Student enrolment data total

Students participating in the 30% of 9 Data of competitions at various levels and ERP competitive activities total

Participating Universities and Colleges will have to develop an action plan to achieve the following parameters in a time bound manner and sign an agreement

A. Improving the research outcomes and quality of faculty in such a way that the participating Universities are either ranked among top-100 in the country in next 7 years or attain NAAC A or equivalent grade. For this purpose, they can also access KCG's ongoing Quality Improvement Project on preferential basis; B. 50% of the Departments of Universities and Colleges, participating in this initiative must have NAAC A accreditation in next 7 years. Rest should have at least NAAC B accreditation or equivalent. A clear and acceptable road map will be a pre-condition to joining this Project; C. The Departments of Universities and participating have to ensure within the next 7 years, 75% of the passing out students should be employable. Universities must develop annual performance targets, monitor them and ensure that final targets are achieved by the 7th year. This parameter will be monitored through a web based programme; D. Every participating entity will set up a students' managed internship &placement cell; E. 100% students must join some personality development or skill improvement activity;

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F. 10% of faculty of participating departments and colleges must work on Gujarat specific issues; G. Universities must receive at least 15% support from UGC, projects, consultancies or donations. Participating Government colleges must mobilize at least 5% contribution from community. H. All the departments and affiliated colleges must install biometric based attendance system for the faculty and students. I. UGC mandated API scores should be compulsory for promotion and confirmation of academic faculty. J. Choice based credit system should be adapted and upscaled in the University and credit transfer scheme must be implemented. Every participating University must aim to develop at least 25 single-credit courses jointly with industry and other prospective employers. Such credit courses can, preferably, be co-branded. and K. All the departments and affiliated colleges must have portals for students' admission, fee payments, attendance monitoring, academic performance of students and their placement record.

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CHAPTER- 4 COMPONENT 7: INFRASTRUCTURE GRANTS TO COLLEGES

MHRD-RUSA released the first instalment of funds for 4 components out of 6 Components approved in 3rd PAB meeting

The first instalment is 25% of the central share (65%) for 2014-15.

Thus, Central Share released so far = 14,62,59,800 + 3,25,00,000 + 3,25,000 = Rs. 17,90,84,800, State contribution =9, 62,47,500.

Funds in the first installment under RUSA in 2014-15: Rs. 27,53,32,300. On 29th January 2015, the first installments were released to beneficiary institutions under Components III, VII, IX and XI.

A meeting was held on 29th January 2015 regarding releasing of grants to 35 colleges under Component-7. It was found in the meeting that few colleges are not having their own college building. So, it is proposed that these colleges will be returning the grants sanctioned to them as they cannot utilize it properly as per the RUSA norms due to lack of infrastructure so that these unutlized grants by colleges can be used for other Government Colleges.

Under Component VII, representatives from 35 colleges were invited to KCG and presented with a cheque of Rs. 19, 37,558 (under General i.e. 77.5% of the total first instalment of Rs. 25, 00,075.). Rs 5,62,517 was given to each college for SC and ST categories and thus the first instalment of RUSA funding for the 2014-15 period was completed.

However, in the meeting, PAB approved grants for 35 Govt. Colleges. State has released the first installment for these colleges in the meeting held at KCG dated 29/01/2015.

Total amount of fund available was Rs. 70 crores for 2014-17. PAB sanctioned Rs. 35 Crore for 2014-15. Thus, each College was to get maximum of Rs 1 crores in the year 2014-15.

In this SHEP, 2015-16 it is proposed to provide funding to Govt. colleges with NAAC accreditation or which has applied for NAAC accreditation.

The list of proposed colleges is as follows :( For DCF See Annexure – 3)

1. Shree M. P. Shah Arts & Science College, Surendranagar 2. Government Science College, Gandhinagar 3. Gujarat Arts & Science College, Ahmedabad 4. Government Arts & Commerce College, Ahwa Dangs

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It is proposed that the financial assistance to all colleges would be as per internal ceiling of RUSA Guidelines. Colleges would be provided financial assistance up to 35%, 35% and 30% of total financial assistance for (i) New Equipment/Facility, (ii) Construction and (iii) Renovation respectively.

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Chapter 5 Component 8: Research, Innovation & Quality Improvement

For the year 2015-16, we are proposing a grant of 142.66 crores for following activities. The financial break of the proposed research topic is as given below:

Financial Break Up: Prooposed Nodel Full Detail Proposed Total Sr.No Proposed Research Topics Proposed Network Intitute Institute Project Amount 1 Nanoscienece and Advanced Materials Research University Annexure-5 Rs. 40,00,52,800.00 Interdisciplinary Research in Life Scienece and The Maharaja Sayajirao 2 Intergrated Teaching in Cell and Molecular Annexure-6 Rs. 40,12,00,000.00 University of Baroda Biology 1. 2. Climate Change Impacts Studies on Shoreline 3. The Maharaja Sayajirao 3 Gujarat University Annexure-7 Rs. 40,48,70,000.00 Diversity of Gujarat University of Baroda 4. Hemchandracharya University 4 Post Doctoral Centre in Chemistry Department Saurashtra University Annexure-8 Rs. 3,75,00,000.00 Center of Excellence for Drug Development 5 Saurashtra University Annexure-9 Rs. 4,00,00,000.00 Technology 6 Technologies for Affordable Healthcare Sardar Patel University Annexure-10 Rs. 6,30,00,000.00 Interdisciplinary Studies in Social Sciences and 7 Sardar Patel University Annexure-11 Rs. 4,00,00,000.00 Humanities 8 Research Centre for Area Studies Sardar Patel University Annexure-12 Rs. 4,00,70,000.00

Grand Total Rs. 1,42,66,92,800.00

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Annexure-1

Table-1: Demographic Characteristics of Gujarat

Sr. No. Characteristics Measurement 2011 2001

1 Population Nos. (‘000) 60440 50597 Decadal Growth Rate of Percentage change over the 19.28 22.48 2 Population previous period (2001-2011) (1991-2001) 3 Density of Population Population per sq. km 308 258

4 Sex Ratio Females per 1000 males 919 920 Females per 1000 males in 5 Child-sex Ratio 886 883 the age group 0-6 yrs. Scheduled Caste 6 Percent to total population 6.74 7.41 Population (%) Scheduled Tribe 7 Percent to total population 14.75 14.92 Population (%) 8 Literacy Rate (Total) Percent to total Population 78.03 69.14

9 Literacy Rate (Female) Percent to total literates 70.73 58.60 Work Participation Rate Percent of total workers to 10 40.98 42.10 (Total) total population Work Participation Rate Percent of female workers to 11 23.38 28.03 (Female) total female population 12 Main Workers Percent to total workers 82.22 79.90

13 Marginal Workers Percent to total workers 17.78 20.10

14 Workers in Agriculture Percent to total workers 49.61 52.04 Percent of urban population 15 Degree of Urbanization 42.58 37.35 to total population

Source: Census of India, 2011, 2001.

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Table-2: Population Distribution Across the State

Sr. Total Decadal Growth Density of Sex Ratio District No. Population 2001-2011(P) Population 2011 2001

1 Kachchh 2092371 32.16 46 908 942

2 BanasKantha 3120506 24.61 290 938 930

3 Patan 1343734 13.61 234 935 932

4 Mahesana 2035064 10.73 462 926 927

5 SabarKantha 2428589 16.62 328 952 947

6 Gandhinagar 1391753 4.29 660 923 913

7 Ahmedabad 7214225 24.03 890 904 892

8 Surendranagar 1756268 15.91 167 930 924

9 Rajkot 3804558 20.02 339 927 930

10 2160119 13.44 153 939 941

11 585449 9.06 255 950 946

12 Junagadh 2743082 12.05 310 953 955

13 Amreli 1514190 8.63 205 964 987

14 2880365 16.63 288 933 937

15 Anand 2092745 12.70 711 925 910

16 Kheda 2299885 13.61 541 940 923

17 Panch Mahals 2390776 18.05 458 949 938

18 Dohad 2127086 29.98 582 990 985

19 4165626 14.38 551 934 919

20 Narmada 590297 14.75 214 961 949

21 1551019 13.16 238 925 921

22 The Dangs 228291 22.26 129 1006 987

23 1329672 8.15 602 961 955

24 Valsad 1705678 20.92 561 922 920

25 Surat 6081322 42.24 1376 787 810

26 Tapi 807022 12.14 249 1007 996

Source: Census of India, 2011

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Table-3: Scheduled Caste and Scheduled Tribe Population in Gujarat (%)

District Scheduled Caste Scheduled Tribe

Kachchh 12.37 1.16

BanasKantha 10.49 9.11

Patan 9.18 0.99

Mahesana 7.97 0.46

SabarKantha 7.73 22.32

Gandhinagar 7.80 1.31

Ahmadabad 10.53 1.24

Surendranagar 10.22 1.22

Rajkot 7.63 0.63

Jamnagar 8.05 1.12

Porbandar 8.85 2.23

Junagadh 9.69 2.03

Amreli 8.78 0.48

Bhavnagar 5.45 0.32

Anand 4.99 1.19

Kheda 5.03 1.75

PanchMahals 4.20 30.18

Dohad 1.95 74.32

Vadodara 5.32 27.60

Narmada 1.48 81.55

Bharuch 4.01 31.48

The Dangs 0.43 94.65

Navsari 2.67 48.11

Valsad 2.24 52.93

Surat 2.60 14.09

Tapi 1.01 84.18

Source: Census of India, 2011

16 Gujarat State Higher Education Plan 2015-16

Table-4: District-wise Literacy Rate in Gujarat (%), 2011

District Persons Males Females

Ahmadabad 85.31 90.74 79.35

Amreli 74.25 82.21 66.09

Anand 84.37 91.82 76.36

Banaskantha 65.32 78.15 51.75

Bharuch 81.51 87.45 75.09

Bhavnagar 75.52 84.39 66.08

Dohad 58.82 70.01 47.65

Gandhinagar 84.16 92.01 75.76

Jamnagar 73.65 81.5 65.33

Junagadh 75.8 84.38 66.86

Kachchh 70.59 79.4 60.87

Kheda 82.65 91.31 73.49

Mahesana 83.61 91.39 75.32

Narmada 72.31 81.19 63.09

Navsari 83.88 88.75 78.83

PanchMahals 70.99 82.51 58.89

Patan 72.3 82.9 61.05

Porbandar 75.78 83.45 67.75

Rajkot 80.96 87.07 74.43

Sabarkantha 75.79 86.44 64.69

Surat 85.53 89.56 80.37

Surendranagar 72.13 82.11 61.45

Tapi 68.26 75.44 61.16

The Dangs 75.16 83.06 67.38

Vadodara 78.92 85.39 72.03

Valsad 78.55 84.55 72.06

Source: Census of India, 2011.

17 Gujarat State Higher Education Plan 2015-16

Table-5: District-wise Work Force Participation in Gujarat (%)

Work Participation Rate Main Marginal Agricultural District Total Male Female Workers Workers Workers

Kachchh 37.10 56.96 15.22 88.50 11.50 37.34

BanasKantha 40.01 51.93 27.30 81.06 18.94 66.16

Patan 41.29 55.17 26.45 80.43 19.57 65.55

Mahesana 39.90 55.72 22.83 86.05 13.95 53.29

SabarKantha 44.67 54.77 34.06 73.29 26.71 64.58

Gandhinagar 38.44 56.37 19.00 84.48 15.52 43.65

Ahmadabad 35.97 56.16 13.64 89.88 10.12 15.86

Surendranagar 41.20 55.39 25.93 81.05 18.95 63.04

Rajkot 38.88 58.72 17.46 89.57 10.43 38.11

Jamnagar 39.23 58.05 19.18 85.11 14.89 48.56

Porbandar 39.49 58.00 20.00 84.54 15.46 49.60

Junagadh 40.97 57.10 24.04 83.89 16.11 62.41

Amreli 43.40 58.83 27.38 80.52 19.48 67.27

Bhavnagar 39.95 56.29 22.43 86.23 13.77 49.17

Anand 40.37 57.72 21.60 81.68 18.32 59.04

Kheda 40.61 56.89 23.28 77.32 22.68 64.14

PanchMahals 45.91 54.90 36.43 62.43 37.57 75.88

Dohad 46.97 50.61 43.29 55.39 44.61 82.79

Vadodara 40.65 57.26 22.87 80.35 19.65 52.11

Narmada 49.94 57.88 41.67 65.78 34.22 85.09

Bharuch 40.43 58.20 21.23 83.96 16.04 52.89

The Dangs 51.80 53.88 49.73 74.45 25.55 88.83

Navsari 44.51 60.14 28.23 86.17 13.83 53.97

Valsad 43.57 58.18 27.74 77.68 22.32 44.48

Surat 41.99 62.98 15.33 94.19 5.81 17.05

Tapi 55.87 62.42 49.37 74.87 25.13 79.95

Source: Census of India, 2011

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Table-6: District-wise Rural-Urban Distribution of Population

District Total Rural Urban

Kachchh 2092371 1363836 (65.18) 728535(34.82)

BanasKantha 3120506 2705591(86.70) 414915(13.30)

Patan 1343734 1062653(79.08) 281081(20.92)

Mahesana 2035064 1520734(74.73) 514330(25.27)

SabarKantha 2428589 2064869(85.02) 363720(14.98)

Gandhinagar 1391753 791126(56.84) 600627(43.16)

Ahmadabad 7214225 1151178(15.96) 6063047(84.04)

Surendranagar 1756268 1259352(71.71) 496916(28.29)

Rajkot 3804558 1590508(41.81) 2214050(58.19)

Jamnagar 2160119 1189054(55.05) 971065(44.95)

Porbandar 585449 299775(51.20) 285674(48.80)

Junagadh 2743082 1836670(66.96) 906412(33.04)

Amreli 1514190 1127555(74.47) 386635(25.53)

Bhavnagar 2880365 1697964(58.95) 1182401(41.05)

Anand 2092745 1457758(69.66) 634987(30.34)

Kheda 2299885 1776276(77.23) 523609(22.77)

PanchMahals 2390776 2055949(86.00) 334827(14.00)

Dohad 2127086 1935461(90.99) 191625 (9.01)

Vadodara 4165626 2099855(50.41) 2065771(49.59)

Narmada 590297 528425(89.52) 61872(10.48)

Bharuch 1551019 1026060(66.15) 524959(33.85)

The Dangs 228291 203604(89.19) 24687(10.81)

Navsari 1329672 920535(69.23) 409137(30.77)

Valsad 1705678 1070177(62.74) 635501(37.26)

Surat 6081322 1232109(20.26) 4849213(79.74)

Tapi 807022 727535(90.15) 79487(9.85)

Source: Census of India, 2011

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Figure – 1 Trend of Gross Enrolment in Higher Education in Gujarat (Since 1960-61)

Source: (1) Educational Statistics, 1998-99, Government of Gujarat, (2) Department of Higher Education, Government of Gujarat, (3) All-India Survey on Higher Education, 201011, Ministry of Human Resource Development, Government of India.

Figure - 2 Gender Wise Distribution of Gross Enrolment in Higher Education in Gujarat

90 85.43

80 73.17 70 67.51 58.58 58.99 60 56.04 56.01

50 43.96 43.99 41.42 41.01 Boys 40 32.49 Girls 30 26.83

20 14.57

10

0 1960-61 1970-71 1980-81 1990-91 2000-01 2010-11 2014-15

Source: (1) Educational Statistics, 1998-99, Government of Gujarat, (2) Department of Higher Education, Government of Gujarat, (3) All-India Survey on Higher Education, 2010-11 &2014-15, Ministry of Human Resource Development, Government of India.

20 Gujarat State Higher Education Plan 2015-16

Table-7: Category wise Distribution of Gross Enrolment Ratios in Gujarat (2010-11)

Categories Total Boys Girls

All categories 20.1 22.5 17.5

Scheduled Caste 24.2 26.4 21.8

Scheduled Tribe 13.1 13.4 12.8

Source: All-India Survey on Higher Education, 2014-15, Ministry of Human Resource Development, Government of India.

Table-8: Category wise Gender Gap at Different Levels of Higher Education in Gujarat

Level Agriculture Arts Commerce Education Engg & Tech Law Management Medical Science Total Male 190 384 63 100 553 17 264 266 514 2351 Ph.D Female 71 322 49 83 206 14 170 143 279 1337 Total 261 706 112 183 759 31 434 409 793 3688 Male 0 264 31 118 22 14 18 0 27 494 M.Phil Female 0 270 42 59 29 7 12 0 60 479 Total 0 534 73 177 51 21 30 0 87 973

Post Male 662 11440 6551 2653 18054 819 10712 3690 5851 60432 Graduate Female 288 18025 9197 4517 10303 623 6805 3503 6170 59431 Total 950 29465 15748 7170 28357 1442 17517 7193 12021 119863

Under Male 2582 159739 150684 11304 202892 10841 19954 14925 53518 626439 Graduate Female 1364 153944 126849 19252 59766 6391 13910 30532 43031 455039 Total 3946 313683 277533 30556 262658 17232 33864 45457 96549 1081478

PG Male 0 246 206 125 1630 307 714 164 193 3585 Diploma Female 0 204 90 222 1394 180 373 228 175 2866 Total 0 450 296 347 3024 487 1087 392 368 6451 Male 1018 438 106 1501 111461 273 334 1605 453 117189 Diploma Female 447 462 38 1540 17161 141 127 8582 75 28573 Total 1465 900 144 3041 128622 414 461 10187 528 145762 Male 0 658 127 1517 9356 0 100 69 395 12222 Certificate Female 0 7912 30 2802 7841 0 49 145 249 19028 Total 0 8570 157 4319 17197 0 149 214 644 31250 Male 0 385 0 339 1078 1734 345 0 659 4540 Integrated Female 0 278 0 401 753 1218 363 0 1666 4679 Total 0 663 0 740 1831 2952 708 0 2325 9219 Male 4452 173554 157768 17657 345046 14005 32441 20719 61610 827252 Total Female 2170 181417 136295 28876 97453 8574 21809 43133 51705 571432

Source: All-India Survey on Higher Education, 2014-15, Ministry of Human Resource Development, Government of India.

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Table-9: Category wise Gross Enrolment Ratio-2014-15

Caste-Category District Total SC ST OBC Male Female Male Female Male Female Male Female Ahmadabad 157013 119602 16901 14126 10046 9499 38189 24015 Amreli 13456 12814 1139 954 197 107 4313 2953 Anand 51239 28899 2918 1930 3167 2096 10452 5304 Aravalli 72 85 30 42 36 36 5 6 Banas Kantha 23896 10587 3195 1553 1244 487 12067 4729 Bharuch 15673 10863 1025 860 2120 2342 3791 2565 Bhavnagar 28697 17112 1961 1162 1060 468 12986 6735 345 256 23 32 0 1 231 153 Chhota Udepur 188 66 17 2 82 37 70 16 Dohad 13721 10048 1202 839 5673 5111 4098 2591 Gandhinagar 52507 25234 4551 2507 2367 1527 12650 5129 Gir Somnath 13 103 9 71 1 3 3 23 Jamnagar 14307 9020 849 587 411 248 4306 2832 Junagadh 45356 37549 5260 4526 1544 1224 21343 19138 Kachchh 19144 9711 2089 724 572 221 5139 2074 Kheda 21077 12068 1382 1151 566 510 6768 3985 Mahesana 48122 30081 3774 2870 719 923 14489 9337 Mahisagar 76 64 9 19 38 19 27 22 Morbi 192 96 16 32 4 14 43 36 Narmada 2155 1940 63 70 1561 1333 211 196 Navsari 11734 11373 476 493 2338 3248 3657 4125 Panch Mahals 14868 11101 1164 1009 3708 3234 5486 3744 Patan 20929 11567 2513 1451 720 411 10640 4613 Porbandar 4989 4366 357 398 88 65 2057 2610 Rajkot 80591 53053 4853 2980 1807 1644 19440 11316 Sabar Kantha 37957 26223 5281 4175 5487 4455 12722 7507 Surat 65026 56874 2638 2684 6083 8422 15439 12871 Surendranagar 15094 9237 1543 1095 229 105 6549 3358 Tapi 3489 4710 82 103 2736 3652 309 417 The Dangs 1173 689 41 18 755 540 186 74 Vadodara 51730 33386 3024 2086 4931 3117 8622 4046 Valsad 12423 12655 666 516 3677 4990 3334 3942 All Districts 827252 571432 69051 51065 63967 60089 239622 150462

Source: All-India Survey on Higher Education, 2014-15, Ministry of Human Resource Development, Government of India.

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Table: 10- Level wise Gross Enrolment -2014-15

Level Ph.D M.Phil Post Graduate Under Graduate PG Diploma District Male Female Male Female Male Female Male Female Male Female Ahmadabad 695 414 133 76 15444 14661 116498 82028 816 570 Amreli 139 433 11673 11504 38 58

Anand 183 126 92 91 7766 5113 39196 21765 303 159 Aravalli 15 35

Banas Kantha 22 4 902 758 21005 9595 17 15

Bharuch 506 739 10867 9074

Bhavnagar 146 85 19 26 1383 1250 23727 14819 20 26 Botad 345 243

Chhota Udepur 188 66

Dohad 0 1 661 742 11580 8222

Gandhinagar 388 230 28 57 4533 3514 37374 18239 257 97 Gir Somnath

Jamnagar 28 8 580 530 11491 7993 40 37

Junagadh 185 53 36 8 1446 1552 37621 33783 1141 863 Kachchh 0 7 3 0 684 611 13573 8046 21 9 Kheda 15 7 1472 1620 14428 9784

Mahesana 75 26 28 20 3960 5201 35196 23194 68 111 Mahisagar

Morbi 189 30

Narmada 104 106 1962 1678

Navsari 41 11 644 589 9384 10191

Panch Mahals 2 0 160 233 13580 10639

Patan 63 26 98 74 1843 1808 16119 8754 21 19 Porbandar 183 171 3526 3876 37 17

Rajkot 274 111 6398 4998 58114 45097 326 342

Sabar Kantha 10 0 2210 2464 31425 22403 117 104

Surat 105 84 49 110 4374 6498 48354 44956 83 94 Surendranagar 73 70 6 13 749 564 11596 7993 45 34 Tapi 67 297 3317 4212

The Dangs 808 563

Vadodara 43 65 3517 3361 34259 25841 216 249

Valsad 3 9 2 4 707 1618 9044 10451 4 27 Grand Total 2351 1337 494 479 60432 59431 626439 455039 3585 2866

Source: All-India Survey on Higher Education, 2014-15, Ministry of Human Resource Development, Government of India.

23 Gujarat State Higher Education Plan 2015-16

Table: 10- Level wise Gross Enrolment Ratio-2014-15 (Continue)

Level Diploma Certificate Integrated Total Grand District Male Female Male Female Male Female Male Female Total Ahmadabad 12329 4940 9988 15781 1110 1132 157013 119602 276615 Amreli 1523 374 83 392 0 53 13456 12814 26270 Anand 2725 955 413 137 561 553 51239 28899 80138 Aravalli 37 33 20 17 72 85 157

Banas Kantha 1897 156 4 44 49 15 23896 10587 34483 Bharuch 3919 855 381 195 15673 10863 26536

Bhavnagar 3354 846 48 60 28697 17112 45809

Botad 0 13 345 256 601

Chhota Udepur 188 66 254

Dohad 1294 909 186 174 13721 10048 23769

Gandhinagar 8541 1832 383 426 1003 839 52507 25234 77741 Gir Somnath 1 65 12 38 13 103 116

Jamnagar 2168 452 0 0 14307 9020 23327

Junagadh 4804 1016 81 167 42 58 45356 37500 82856 Kachchh 4654 861 76 42 133 135 19144 9711 28855 Kheda 5159 486 3 171 21077 12068 33145

Mahesana 8605 1190 92 252 98 87 48122 30081 78203 Mahisagar 0 51 76 13 76 64 140

Morbi 3 66 192 96 288

Narmada 89 116 0 40 2155 1940 4095

Navsari 1665 536 0 46 11734 11373 23107

Panch Mahals 1068 152 58 77 14868 11101 25969

Patan 2378 598 124 104 283 184 20929 11567 32496 Porbandar 1238 283 5 19 4989 4366 9355

Rajkot 15323 2192 50 253 106 60 80591 53053 133644 Sabar Kantha 3747 893 425 348 23 11 37957 26223 64180 Surat 11322 3662 7 121 732 1349 65026 56874 121900 Surendranagar 2617 497 0 66 8 0 15094 9237 24331 Tapi 87 148 18 53 3489 4710 8199

The Dangs 365 126 1173 689 1862

Vadodara 13614 3688 70 174 11 8 51730 33386 85116 Valsad 2663 546 12423 12655 25078

Grand Total 117189 28524 12222 19028 4540 4679 827252 571383 1398635 Source: All-India Survey on Higher Education, 2014-15, Ministry of Human Resource Development, Government of India.

24 Gujarat State Higher Education Plan 2015-16

Table-11: Number of Institutions for Higher Education (Degree Level and Above) in Gujarat

Universities/ Medical Colleges Deemed Arts, Science Engg., (Allop/Ayur/ Teacher Universities/ Research & Tech., & Year Homeo/Unani/ Training Others Institutions of Institutions Commerce Arch. Nurs./Pharm. Colleges National Colleges Colleges Etc. Importance 1986- 10 11 215 11 26 39 51 1987* 1996- 11 11 303 14 26 42 89 1997* 1997- 11 11 317 23 43 42 64 1998* 1998- 11 11 339 15 33 42 79 1999* 1999- 11 11 339 25 33 42 77 2000* 2000- 11 16 422 29 41 42 86 2001* 2001- 12 16 422 29 41 51 107 2002* 2002- 12 16 422 31 41 51 107 2003* 2003- 12 16 422 32 41 51 111 2004* 2004- 14 17 507 44 57 115 177 2005* 2014-15 68 15 904 178 180 168 531

*Provisional Source: (1) Ministry of Human Resource Development, Govt. of India, (2) RashtriyaUchchatarShikshaAbhiyan, National Higher Education Mission, Ministry of Human Resource Development, Page no. 182-183, (3) Original Source: University Grants Commission Annual Report, 2011-12.

Source: All-India Survey on Higher Education, 2014-15, Ministry of Human Resource Development, Govt. of India.

25 Gujarat State Higher Education Plan 2015-16

Annexure-2 Meritorious fellows

To promote research work in the state, students who have completed their post graduation in last two years will be selected and they will be provided fellowship for 24 months and they will be selected through competitive selection process on the lines of SLET.

Following activities will be conducted to realize this scheme

Frame work of Programme for meritorious fellows will be developed by esteemed Academic committee

Advertisement for invitation of Online Application for fellowship

Application will be scrutinised

Online Examination will be conducted in selected major centre

Online answer of candidate to be checked

After careful scrutinised result to declared

Selected candidate to be attached with universities, colleges and research institution for next two year to

Pursue research work.

Time to time monitoring will be conducted check the progress of Research fellow.

26 Gujarat State Higher Education Plan 2015-16

Annexure- 3

Basic Details of Colleges for Component -7: Infrastructure Grant to Colleges

Indicator Unit College 1 College 2 College 3 College 4 Shree M. P. Governme Government Shah Arts & Gujarat Arts nt Science Arts & Name of the Science & Science 4 College, Commerce College College, College, Gandhinag College, Ahwa Surendrana Ahmedabad ar Dangs gar Surendrana Gandhinag District Name Ahmedabad The Dangs gar ar Category Categ Governme (Govt./Aided/Priv Government Government Government ory nt ate) B (29/1/2019) LOI Submitted LOI (15/5/2015) NAAC Grad Submitted B B Waiting for Accreditation e (1/4/2015) NAAC peer Waiting for Team Visit NAAC peer Team Visit Whether included Yes under 12B of UCG Yes Yes Yes Yes /no Act Pls. Area of the Specify Categ proposed College (Tier- Tier-I Tier-I Tier-I Tier-I ory fall under 1/Tier- 2/Tier-3 ) Year of Year 1956 1970 1863 1970 establishment Number of Num 4565 1124 3512 1001 students enrolled ber Number/ Ratio SC 768 63 469 12 total Number/ Ratio ST 33 178 211 944 total Number/ Ratio OBC 2213 381 1166 28 total Number/ Ratio Women students 1767 415 913 428 total

27 Gujarat State Higher Education Plan 2015-16

Financial Layout for Component -7: Infrastructure Grant to Colleges

College – 1 College – 2 Shree M. P. Shah Arts & Science College, Government Science College, Gandhinagar Surendranagar Details of existing college Physical Physical New Construction Financial New Construction Financial Value Value /Renovation (Pls. Value (Rs. /Renovation (Pls. Value (Rs. (Area in (Area in Specify) in lakhs) Specify) in lakhs) Sq.Mt) Sq.Mt) Hostels (Separate for boys and girls) New construction New construction 35

Toilets (Separate for boys and girls) New construction 5 New construction 24 4

Laboratory New Construction 1600 20 New Construction 48 10 Computer Centre New Construction 800 30 New Construction 48 10 Classrooms (including technologically enabled classrooms) New Construction 800 10 New Construction 48 8 Common room for students New Construction 600 3 New Construction 12 2 Canteen/Cafeteria New Construction 2 New Construction 1

Academic Buildings Renovation 5 Renovation 7

Administrative buildings Renovation 800 5 Renovation 622.835 7 Campus development Renovation 4 Renovation 183605.6 5

Toilet Renovation 2 Renovation 138.329 2

Library Renovation 1600 20 Renovation 800 20 Class room Renovation 5000 5 Renovation 1384.32 10 Canteen/Cafeteria Renovation Renovation 1

Laboratory Renovation 4000 17 Renovation 860.034 13 Computer centre Renovation 800 12 Renovation 84.68 5 Sports facility New equipment /facility 10 New equipment /facility 15

Computers New equipment /facility 10 New equipment /facility 10

Books New equipment /facility 15 New equipment /facility 15

Journals/e-Resources New equipment /facility 25 New equipment /facility 20

Total 200 200

28 Gujarat State Higher Education Plan 2015-16

College – 3 College – 4 Gujarat Arts & Science College, Ahmedabad Government Arts & Commerce College, Ahwa Dangs Physical Financial Physical Details of existing college Financial New Construction Value Value New Construction Value Value (Rs. /Renovation (Area (Rs. in /Renovation (Area in lakhs) Sq.Mt.) lakhs) Sq.Mt.) Hostels (Separate for boys and girls) New construction 10000 34 New construction 34 Toilets (Separate for boys and girls) New construction 250 3 New construction 3 Laboratory New Construction 100 10 New Construction 10 Computer Centre New Construction 100 10 New Construction 10 Classrooms (including technologically enabled classrooms) New Construction 200 10 New Construction 10 Common room for students New Construction 100 2 New Construction 2 Canteen/Cafeteria New Construction 50 1 New Construction 1 Academic Buildings Renovation 500 10 Renovation 10 Administrative buildings Renovation 200 5 Renovation 5 Campus development Renovation 130000 10 Renovation 10 Toilet Renovation 250 2 Renovation 2 Library Renovation 2000 20 Renovation 20 Class room Renovation 500 5 Renovation 5 Canteen/Cafeteria Renovation 100 1 Renovation 1 Laboratory Renovation 2000 12 Renovation 12 Computer centre Renovation 500 5 Renovation 5 Sports facility New equipment /facility 15 New equipment /facility 15

Computers New equipment /facility 10 New equipment /facility 10

Books New equipment /facility 15 New equipment /facility 15

Journals/e-Resources New equipment /facility 20 New equipment /facility 20

Total 200 200

29 Gujarat State Higher Education Plan 2015-16

Annexure- 4

Basic Details of Universities for Component -8: Research, Innnovation & Quality Improvement

Indicator Unit University 1 University 2 University 3 The Maharaja Name of the Saurashtra Sayajirao Gujarat 6 College University University of University Baroda District Name Rajkot Vadodara Ahmedabad Category Category State Public State Public State Public B (28/03/2010) NAAC A LOI Submitted B Accreditation and Grade (23/09/2019) (24/07/2015) (30/04/2020) Validity Waiting for NAAC peer Team Visit Whether included under 12B of UCG Yes /no Yes Yes Yes Act Area of the Pls. Specify (Tier- proposed College Category Tier-I Tier-I Tier-I 1/Tier-2/Tier-3 ) fall under Year of Year 1967 1949 1949 establishment Number of (2014-15) Number 218526 22926 255626 students enrolled Ratio SC Number/total 19526 1290 26892

Ratio ST Number/total 5021 944 28114

Ratio OBC Number/total 83436 1999 64745

Ratio Women students Number/total 109278 13032 120650

30 Gujarat State Higher Education Plan 2015-16

Indicator Unit University 4 University 5 University 6 Hemchandracharya M. K. Name of the Sardar Patel 6 North Gujarat Bhavnagar College University University University District Name Anand Patan Bhavnagar Category Category State Public State Public State Public B B (31/03/2007) (16/09/2008) LOI Submitted NAAC B LOI Submitted Grade (03/05/2013) Accreditation (15/09/2016) (17/04/2014) Waiting for Waiting for NAAC peer NAAC peer Team Visit Team Visit Whether included under Yes /no Yes Yes Yes 12B of UCG Act Area of the Pls. Specify proposed (Tier-1/Tier- Category Tier-I Tier-I Tier-I College fall 2/Tier-3 ) under Year of Year 1955 1986 1978 establishment Number of students (2014-15) Number 42615 154591 35821 enrolled Ratio SC Number/total 2827 21061 2523

Ratio ST Number/total 3630 12273 523

Ratio OBC Number/total 7760 63412 16620

Women Ratio Number/total 17284 69068 15996 students

31 Gujarat State Higher Education Plan 2015-16

Annexure: 5 Proposal for Nanoscience and Advanced Materials Research Under Research and Innovation (Component no. 8) of MHRD-RUSA Scheme

Submitted by Saurashtra University, Rajkot December 5, 2015

32 Gujarat State Higher Education Plan 2015-16

PART A

1. Outcome and focus area of research proposal

 Saurashtra University is a Government of Gujarat affiliated university established in 1967 and is one of the largest University in Gujarat catering to the need of higher education in Gujarat. University is running various UG and PG programs and has large number of affiliated colleges spread in nine districts of Saurashtra region. It has established itself as the highest ranking University in Gujarat accredited with “A” Grade (CGPA-3.05) by NAAC in terms of educating the students for better career and job placements in respective fields and shape them into a responsible citizen of India. University has also generated excellent manpower for academic and research fields. For this, it has foreseen appreciable quality enrolment of PG and UG students in all the disciplines of science, management, humanities, social sciences, etc.

 Scientific research and development is the most important aspect of human development with its applications and implications in all walks of life. At the base of every scientific discovery or invention lies the inquisitive mind and desire to learn and develop newer things. Scientific research is a systematic & meaningful investigation to understand and apply various phenomena, materials, systems, devices, etc. for the betterment of mankind. No applied scientific research can be possible without sophisticated instrumentation and equipments required to perform the experiments in the laboratory. It is an undoubted and worldwide accepted fact that the twenty first century will witness many landmark discoveries and inventions in the scientific and technological fields as a result of ever increasing interest and financial support to the scientific research and development.

 Developments in the fields of Nanoscience & Nanotechnology, Nanomaterials, embedded systems & devices, etc. have attracted a major national funding and developments. Government of India has identified various scientific funding agencies such as MHRD, Dept. of Science & Technology (DST), Dept. of Biotechnology (DBT), Dept. of Scientific & Industrial Research (DSIR), Council of Scientific & Industrial Research (CSIR), Dept. of Atomic Energy (DAE), University Grant Commission (UGC), Defense Research & Development Authority (DRDO), All India Council of Technical Education (AICTE), Ministry of Information Technology (MIT) etc. for promotion of scientific research and

33 Gujarat State Higher Education Plan 2015-16

development in Universities which requires expertise for the development of new materials in the form of bulk, thin film, multilayers & devices for meeting the challenges of the technological society.

 The following focused areas of research and development in basic and Applied Nanoscience and Advanced Materials have been identified by Saurashtra University under the proposal for research and innovation submitted to MHRD-RUSA for funding during 2015-20 (FIVE Years).

 Establishment of ‘state of art’ research and innovation facilities for experimental research in the field of Nanoscience & Nanotechnology and Advanced Materials development.

 To establish a strong linkage between Saurashtra University and Industries involved in ceramics, new materials development, composites and their applications, etc.

 Manpower training and development in the field of Applied Sciences such as Nanoscience and Nanotechnology and Advanced Materials.

2. Scalability and Sustainability of the Project proposed

 Duration of project: 2015-2020 (FIVE Years)  The proposed research in Nanoscience and Nanotechnology under the existing Centre of Excellence (COE) existing at Saurashtra University will be able to sustain for a long time by way of providing the consultancy, prototype development and new materials for industrial applications.

 Proposed consultancy services to be offered : FIVE (Nanomaterials Synthesis, Characterization and Applications)

 Proposed prototypes/products to be developed: FIVE (High-k ceramics for insulation applications, thin film devices for memory switching applications and Nano sensors, Nano clays and Nano pigments for ceramic and rubber industries, etc.)

34 Gujarat State Higher Education Plan 2015-16

3. Prioritization on area of research done by Saurashtra University

 Priority Research Area:

 Synthesis and development of Nanomaterials and Nanostructured thin films for industrial and IT applications.

 Development of Industry-University linkage in the field of Nanomaterials and their applications.

 Development of new products/devices suitable for applications.

4. Quality of Institution (NAAC Grade) and Faculty undertaking the research

 Saurashtra University is “A” Grade with CGPA (3.05) accredited by NAAC.

 Faculties involved in this proposal: 10 (TEN) from Department of Physics & Department of Nanoscience and Advanced Materials of Saurashtra University, Rajkot and from Department of Physics and Department of Chemistry, Gujarat university, Ahmedabad.

 All the faculties are experts in the field of Material Science, Nanomaterials and Applied Physics. (Details given in Item-3 Part B of this proposal)

5. Accountability of the project (individual/state) (a compulsory MoU will be signed between RUSA and SHEC to further get, the proposal vetted by expert committee under supervision of SHEC)

 Saurashtra University, a Government of Gujarat state level affiliated University will act as nodal University (Center) to undertake the proposed research in Nanoscience and Advanced Materials under MHRD-RUSA project.

35 Gujarat State Higher Education Plan 2015-16

6. Phases/implementation milestones and plan of action for 2015-16 and 2016-17

2015-16 (FIRST YEAR)

 Procurement of the major research instruments and facilities for Nanoscience, Nanotechnology, appointment of project fellows and scientific staff.

2016-17 (SECOND YEAR)

 Installation and establishment of major facilities, training and development for research and innovation in the area of Nanoscience and Advanced Materials.

2017-18 (THIRD YEAR)

 Synthesis and Characterization of various types of new Nanomaterials in the form of powders, Nano fibers, Nano tubes, Nano wires, Nanostructured films and devices for possible applications.

 Training of project fellows for undertaking advanced research.

2018-19 (FOURTH YEAR)

 Development of new products & prototypes for industrial applications.

 Development of University-Industry linkage by training industry persons, providing consultancy and expert advice for industrial issues in the field of new material technologies and applications.

2019-20 (FIFTH YEAR)

 Setting up of prototype development center for industry specific applications.

 Communicating research results to reputed journals and project report writing.

36 Gujarat State Higher Education Plan 2015-16

7. Financial resources, financial plans, and financial sustainability: fund availability, avoidance of duplication, and plan for financial sustainability/raising resources

 Financial resources: Fund availability

 Saurashtra University will provide necessary infrastructure, building and administrative support for housing modern facilities for Nanoscience and Advanced Materials research to be carried out under R&I scheme of RUSA.

 Major equipments and Manpower will be supported by RUSA and Government of Gujarat.

 Avoidance of duplication

 Major facilities such as TEM, FE-SEM, PLD etc. to be established at Saurashtra University, will be the only facilities in the entire state of Gujarat which will be available for researchers.

 The major research equipments and facilities to be procured will be unique of its kind and the duplication of equipments will be avoided so that more facilities can be established for better research.

37 Gujarat State Higher Education Plan 2015-16

. Financial Plans A) Hard Component (60% of the estimated budget)

Sr. Rs. in Major Equipments & Facilities Proposed No. Lakhs Synthesis 1 Nanostructured Thin Film Deposition (PLD) Facility 200.00 2 PV-CVD & High Temperature Furnaces (RT – 1400oC, RT – 1700oC) 50.00 3 Spray Pyrolysis, DC-RF, Dip Coaters, Spin Coaters, Nanostructured Film 50.00 Deposition Facilities 4 Nanomaterials Synthesis Laboratory (Minor Equipments, Sieve Shakers, 50.00 Ovens, Distillation Plant etc.) 5 Thin Film Profilometer 40.00 6 Particle Size Analyzer 25.00 Microscopy 7 Transmission Electron Microscope with sample preparation facility (TEM) 700.00 8 Field Emission Scanning Electron Microscope (FE-SEM) with correlative 300.00 microscope 9 Atomic Force Microscope with Nano Indenter/ Piezo Force Microscope 200.00 Attachment Transport and Magnetic Properties 10 SQUID/VSM For Magnetic Property Studies 300.00 11 Physical Property Measurement System (PPMS) (Cryo free) (RT-4.2K) 200.00 12 Transport Property Test Station (Semiconductor Test Station) with 80.00 Microscope 13 Raman Spectrometer 50.00 Electrical Backup and Computational Facilities 14 Diesel Power Generator (200 KeV) & UPS Power Backup Facilities (20 100.00 KeV), (5 KeV) etc. Water Chiller etc. 15 Networking & Computation Facilities PC’s, Printer, Plotter, etc. 50.00 16 Research Laboratory Minor Instruments (Multi-meters, Source Meters, Oscilloscope, High & Low Resistance Meters, Test & Measuring 25.00 Equipments etc.) Total (A) 2420.00

38 Gujarat State Higher Education Plan 2015-16

B) Soft Component (40% of estimated budget)

1. Manpower Requirements

Research Post University Nos. Salary/Month Salary/Year Salary for 5 Total (in Rs.) (in Rs.) Years Salary (in Rs.) Saurashtra 06 26,040.00 3,12,480.00 15,62,400.00 93,74,400.00 Project Uni. Rajkot Fellows Gujarat Uni. 06 26,040.00 3,12,480.00 15,62,400.00 93,74,400.00 Ahmedabad Saurashtra 06 43,200.00 5,18,400.00 25,92,000.00 1,55,52,000.00 Research Uni. Rajkot Associate Gujarat Uni. 06 43,200.00 5,18,400.00 25,92,000.00 1,55,52,000.00 Ahmedabad Technical Scientific Saurashtra 06 20,000.00 2,40,000.00 12,00,000 72,00,000 Assistants Uni. Rajkot (Rajkot) Total 5,70,52,800.00

Rs. 570.528 Lakhs

2. Students/Faculty Exchange/e-resources/Prototype Development

Sr. Rs. in Lakhs No. 1 Visiting Scientists/ Faculties 100.00 2 Travel and Field Work 100.00 3 Contingency Expenditure 60.00 4 Books & Journals (e - resource) 150.00 5 Softwares (Labview, MatLab, Simulation Softwares, JCPDS database etc.) 150.00 6 Innovation hub & Prototype Developments Facilities 150.00 7 Students/ faculty Exchange Program 100.00 8 Organization of Workshops/ Training Programs/ Conferences/ Seminars / 100.00 Courses 9 Furniture, Fixtures, Central AC, R.O Purifiers, etc. 100.00 Total 1010.00

39 Gujarat State Higher Education Plan 2015-16

Section Total Budgetary Requirements Rs. in Lakhs A Hard Component (60% of estimated budget) 2420.000 Soft Component Manpower Requirements (40% of estimated B Research & Technical 570.528 budget) Students/Faculty Exchange/e-resources/Prototype 1010.000 Development Grand Total 4000.582

8. Quality improvement/gap filling projection in the form of Building of academic/research capacity of manpower (students and teachers) and in the form of improvement of equipment/facilities

 Creation of Academic/Research Capacity

 As a result of establishment of proposed advanced facilities for research in Nanoscience and Advanced Materials, every year about 20 (TWENTY) Ph.D. Students and 05 (FIVE) teaching faculties will be trained for undertaking industry specific research and product development.

 More number of research articles (presently about 10/year and projected about 20/year) will be published as an improvement in the quality and quantity of research output. The present range of impact factor of published papers is 0.0-3.0 which will be improved to 1.0-4.0 in the field of Physics and Material Science.

 It will be possible to improve the experimental research facilities for materials research which will help to undertake frontline research in the areas such as Carbon Nanotubes (CNT’s), Quantum Dots (QD), Energy conversion, Memory storage and Switching, Nano sensors, etc.

 Under the MHRD-RUSA research and innovation programme, it is proposed to establish a modern and sophisticated instrument facility for basic and applied research which will help to undertake the research in various areas suitable for industries. Also, it will be possible to improve quality of existing research and train the present students and faculties to perform better at National and International level.

40 Gujarat State Higher Education Plan 2015-16

9. Evidence/plan of academic-industry partnership

 University already have Institute-Industry Interaction cell (IIIC) to promote activities for University-Industry collaborations and partnership.

MOUs Particulars 2009 2014

Total Signed 26 29 National level 23 19

International level 03 10

Industrial and Academic Consultancy Particulars 2009 2014

Departments Engaged 07 07 (Chemistry, Physics, Pharmacy, Bio-Science, Management, etc.)

Revenue Generated (in Lacs) 12.87 54.57

10. Promotion of innovation - innovation/incubation hubs, supporting start- ups/entrepreneurs Wherever Applicable

 University has an independent IPR policy and patent development cell under which various patents have been filed and obtained by Departments of Physics, Chemistry, and Pharmaceutical Sciences.

 It is proposed to establish independent innovation/incubation hub for the applications of Nanomaterials and Nano Devices in industries and other sectors of life.

 A prototype development center will be established for the young entrepreneurs and scientists for helping to realize their ideas and new products based on Nanomaterials and new advanced materials such as composites, polymers, elastomers, etc.

41 Gujarat State Higher Education Plan 2015-16

11. Manpower augmentation/recruitment or engagement of highly qualified researchers - Wherever Applicable

 The following highly qualified researchers are required to operate and maintain sophisticated instruments for day to day operations under central instruments facility (proposed) in this project.

1. Project Fellows : 12 Posts

2. Research Associates : 12 Posts

3. Scientific Assistants : 06 Posts (for day to day running and maintenance of equipments)

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PART B

1. Existing body of research work in that area - (fresh proposals not allowed). Fit and credibility of past work, Past achievements of proposed centre/concerned research team

 Name of the Center/ Unit working : Center of Excellence (COE) in Nanomaterials and Applications Supported by : Gujarat council of Science and Technology

(GUJCOST) (Government of Gujarat) Name of PI : Prof. D.G. Kuberkar

Name of Co-PI : Prof. N.A. Shah

Year of Establishment : 2005

Sanctioned Amount : Rs. 39.85 Lakhs

Manpower Trained : PhD degrees awarded: 02

Research scholars working: 02

Publications (2005-2014) : 56 (FIFTY SIX) : Range of Impact factor (0.0-3.0) : Source (Scopus) Facilities Established : Nanonics make Atomic Force Microscope (Basic Model) Areas of Research : Mixed Oxide Nano materials, Bulk and thin films, Synthesis, Characterization and device fabrication. Materials Studied : Mixed Valent Manganites, Multiferroics, Nano Powders, Thin films, Diluted Magnetic Semiconductors, HTSC, etc. Research Collaborations : BARC (Mumbai), TIFR (Mumbai), UGC-DAE CSR (Mumbai), UGC-DAE CSR (Indore), IUAC (New Delhi), NIT (Hamirpur), IISER (Bhopal)

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Functions of COE

Research & Industrial Development in Manpower Training & Collaborations & Scientific Awareness Nanoscience & Development Prototype Development Amongst Society Nanotechnology

Developments in the field of Nanoscience at Department of Physics, Saurashtra University, Rajkot

SOL – State of GEL – State of Nanostructured Nanostructured LPMO Manganite LCMO Manganite 2 Size: 50 × 90 nm Size: 15.89 nm

TEM Picture of Nanostructured LSMO Manganite Size: 20 – 40 nm

44 Gujarat State Higher Education Plan 2015-16

200nm 1.0µm

AFM Picture of AFM Picture of Nanostructured Nanostructured LPMO Manganite LPMO Thin Film 2 2 Size: 50 × 90 nm Size: 250×600 nm

AFM Picture of Ion Induced Nanopatterning of 50nm LPSMO Film Pillar Size: 25 – 400 nm

Percolative Transport Through Nanostructured

Al2O3 Insulating Barrier Barrier Size: 1 nm

45 Gujarat State Higher Education Plan 2015-16

TEM Images of Interfaces of Nanostructured Field Effect Device Size: ZnO (50 nm) / LSMO (100

nm) / SNTO (Substrate)

Gel State of Nanostructured Cobalt doped ZnO synthesized by Sol-gel

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Experimental Facilities Available (Above Rs. 5.0 Lakhs):

Name of Equipment Year of Purchase Funding Agency Atomic force microscopy (AFM) 2006 GUJCOST Electromagnet attached with CCR (field up to: 1.2T) 2007 DST BRNS Powder X-ray Diffractometer (XRD) 2008 Govt. of GUJ Ferroelectric Hysteresis Loop Tracer 2008 Govt. of GUJ Aerosol Spectrometer 2008 Govt. of GUJ Digital Ionosonde 2008 Govt. of GUJ Quartz crystal Micro Balance 2008 Govt. of GUJ GPS Receiver 2008 Govt. of GUJ Aethoalometer 2008 Govt. of GUJ P-E loop tracer Marine India Make 2008 UGC - MRP XRD thin films attachments 2009 DST-FIST - I LCR meter for dielectric and capacitance measurements 2009 Sau. Uni. Closed cycle refrigerator (CCR) system (temperature range: 4K – 2009 DST-FIST - I 300K) DC and RF magnetron sputtering unit 2009 DST-FIST - I Ball milling facility 2009 UGC SAP - II UV-Vis facility 2009 UGC SAP - II TGA-DTA-DSC characterization unit 2010 DST FIST - I FTIR measurement unit 2010 Govt. of GUJ Keithley make source meter 2012 DST - SYS Particle Size Analyser 2012 UGC SAP - II High temperature furnace attached with LCR meter (Wayne Kerr) 2013 DAE- BRNS High precision P-E loop tracer 2014 DST - MRP To be purchased Semiconductor Probe Station under UGC – SAP Sanctioned Phase – III Program o High temperature furnace (RT – 1700 C) Sanctioned

2. How convincing is the rationale/ significance/expected contribution of the project  It is envisaged that, the proposed research & investigation activities in Nanoscience and Advanced Materials under RUSA at the Saurashtra University will benefit the majority of stakeholders in the higher education scenario of Saurashtra region in particular and in Gujarat State in general.

 As an outcome of the research being carried out and planned it is expected

47 Gujarat State Higher Education Plan 2015-16

 To generate scientific and skilled manpower for academic and industrial growth of the region.

 To create ‘State of Art’ research and development facilities on the campus

 To motivate young students for undertaking research in frontier areas of Nanoscience & Advanced Materials.

 To develop new novel materials useful for the future energy solutions and Technological Applications by way of industrial collaborations.

3. Credibility (experience and expertise) of persons involved : Specification of PIs and Co- PIs and their scholarship in the concerned area, credibility of other researchers involved

A. Specification of PI and Co-PI at Saurashtra University, Rajkot: Nodal Institute

Name of PI : Prof. D.G. Kuberkar (Department of Physics) Teaching experiences: P.G. Classes (in years): 24 U.G. Classes (in years): 03 Research Experiences (in Years) : 24 No. of Research Articles : 137 Articles / Chapters published in Books : 04 Ongoing and Completed Major Research Projects: Ongoing : 05 Completed : 14 Awards & Recognitions : National : 12 International : 06 Specification of Co-PI at Saurashtra University, Rajkot: Nodal Institute

Name of PI : Prof. N.A. Shah

(Department of Physics)

Teaching experiences: P.G. Classes (in years) : 15

U.G. Classes (in years) : 01

48 Gujarat State Higher Education Plan 2015-16

Research Experiences (in Years) : 18

No. of Research Articles : 60

Articles / Chapters published in Books : 16

Ongoing and Completed Research Projects :

Ongoing : 03

Completed : 04

Number of Ph.Ds Produced (In Last 5 Years) : 06

. Other Faculties at Saurashtra University, Rajkot involved

Name of Faculty Designation Age Major areas of Member Research Professor 54 Prof. H.H. Joshi & Head Magnetic materials Professor 55 Crystal growth and Prof. M.J. Joshi characterizations Prof. H.P. Joshi Professor 54 Ionospheric Physics Asso. 57 Dr. G.J. Baldha Professor Magnetic Materials Asso. 47 Dr. K.B. Modi Professor Magnetic Materials Asst. Professor 49 CMR Manganites and Dr. J.A. Bhalodia Superconductors Asst. Professor 33 Dr. P.S. Solanki Functional Oxides

. Please see Annexure A’ for more details

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B. Specification of PI and Co-PI at Departments of Physics and Chemistry at Gujarat University, Ahmedabad: Network Institute

Principal Investigator: Prof. P. N. Gajjar Head Department of Physics, Gujarat University, Ahmedabad Co- Principal Investigator: Prof. K. H. Chikhalia Head Department of Chemistry, Gujarat University, Ahmedabad

. Other Faculties at Gujarat University, Ahmedabad involved

Name And Major Areas Of Number Of Number Of Designation Research Ph.Ds M.Phil. Produced Of Faculty Registered (Total) (In Last 5 Years) Prof. P. N. Gajjar Computational Condensed 08 14 Professor & Head Matter, Computational Materials Science, Non-Linear Dynamics Dr. V. A. Rana Microwave Dielectrics 04 05 Professor Dr. P. R. Vyas Theoretical Condensed Matter 04 03 Professor Physics Dr. U. S. Joshi Experimental Condensed 09 05 Professor Matter Physics, Electronics Prof. R. B. Jotania Materials Science, Magnetic 06 05 Professor Material Dr. Deepti Tripathi Semiconductor Electronics & 02 02 Associate Professor Microwaves Dr. S. M. Vyas Experimental Condensed 02 03 Assistant Professor Matter Physics Dr. A. B. Patel Theoretical Condensed Matter - - Assistant Professor Physics And Materials Science

. Please see Annexure B for more details.

50 Gujarat State Higher Education Plan 2015-16

4. Definition and significance/value of research outputs/deliverables-reports/papers, product/patent, software/translation to state/national policy framework.

 Definition: Development and establishment of major research and development facilities to undertake frontline research in the fields of Nanomaterials-synthesis, characterization and applications, energy solutions. To establish the University-Industry linkage in the field of Nanomaterials applications. To develop the trained manpower in the field of Nanomaterials and their applications.

 Research significance: By using the newly established major research facilities on Saurashtra University campus, it will be possible to undertake the latest research in basic and Applied Nanoscience and Nanotechnology suitable for industrial application, new entrepreneurship development. The research fellows and scientific staff involved will be exposed to the latest trends in advanced material research and training.

 Research outputs: Using the modern research faculties to be established under RUSA R&I Scheme it will be possible to improve the research outcome in a qualitative and quantitative manner. This will also help to invite the eminent personalities and scientists for advanced level trainings and collaborations. Also, University-Industry linkage will be developed.

5. Clarity of aims, objectives and research questions

Aims and Objectives

 To establish ‘State of Art’ and modern research facilities for undertaking frontline research in Nanoscience and Advanced materials.

 During the course of proposed project the following objectives have been envisaged. The objectives envisaged are

 Synthesis and development of new Nanomaterials, their characterizations and suitable applications.

 To establish modern experimental facilities useful for Nanomaterial synthesis, thin film based device fabrication and applications.

51 Gujarat State Higher Education Plan 2015-16

 To establish a prototype development/incubation center in the field of Nanoscience and Nanotechnology for new product/materials development useful in ceramic industries, rubber industries, paint industries, storage and switching devices and sensors, etc.

 To improve the quality of the research in the field by way of scientific collaboration, manpower training, expert lectures, industrial linkages and patent development.

6. Methodology

Nanoscience & Advanced Materials research

 Developments in the fields of Nanoscience & Nanotechnology, Nanomaterials, embedded systems and devices, etc. have attracted a major national funding and developments. Government of India through its scientific funding agencies like Dept. of Science & Technology (DST), Dept. of Biotechnology (DBT), Dept. of Scientific & Industrial Research (DSIR), Council of Scientific & Industrial Research (CSIR), Dept. of Atomic Energy (DAE), University Grant Commission (UGC), Defense Research & Development Authority (DRDO), All India Council of Technical Education (AICTE), Ministry of Information Technology (MIT) etc. have identified for scientific research and development necessitating expertise for the development of new materials in the form of bulk, thin film, multilayers and devices to meet the challenges of the technological society.

 Considering the above mentioned aspects of research in this field, it is proposed to undertake the synthesis and development of Nanostructured materials suitable for device applications such as switching memories, storage devices and sensors. For this purpose, the existing research facilities and equipments will be used and more research will be carried out using the facilities to be established in future under MHRD-RUSA support.

52 Gujarat State Higher Education Plan 2015-16

7. Definition and significance/value of Concrete outcomes – including

 Creation of more PhDs and postdocs and other additions to talent pool

Ph.Ds produced: 23 (2009-2014) Ph.Ds proposed: 40 (2015-2020)

Post Docs: 03 (2009-2014) Post Docs proposed: 10 (2015-2020)

M.Sc. (Applied Physics): NIL M.Sc. (Applied Physics) proposed: 40

(Nanoscience and Advanced Materials): (Nanoscience and Advanced Materials):

 Using the sophisticated instruments/equipments facilities to be established under RUSA support, more number of doctoral and post-doctoral students will be benefited and will be exposed to the latest development in their respective research areas.

 Research publications, IPR/ Technology Transfer

Total No. of Publications (2010 – 2014): 104 Proposed (2015-2020): 180

Average Impact Factor: 1.58 Average Impact Factor: 3.0

[IF Range: 0.347 – 3.794] [IF Range: 1.00 – 4.00]

Patents (filed/obtained) (2009-2015): 19

Patents proposed: 30 (2015-2020)

8. Inter-disciplinary/multi-disciplinary orientation and multi-institution networking

 The proposed research programme under the RUSA support to be undertaken at Saurashtra University is in true sense of Inter-disciplinary and multi-disciplinary nature.  Departments/ Universities involved in this proposal 1. Department of Physics, Saurashtra University, Rajkot

2. Department of Nanoscience and Advanced Materials, Saurashtra University, Rajkot

3. Department of Physics, Gujarat University, Ahmedabad

4. Department of Chemistry, Gujarat University, Ahmedabad

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9. Anticipated Outcome(s) of the proposal  Societal Benefit:  The proposed project will enhance employability of students in various interdisciplinary areas such as, paint industries, rubber industries, ceramic industries, chemical industries which are actively using Nano-materials for the development of Nano-products.

 Last year, Government of Gujarat provided special budget for the development of Nano Science and Technology based industries in the State which will help to train the young researchers in the field for industries.

 The impact of proposed project extends from its medical, environmental applications to fields such as engineering, biology, chemistry, computing, materials science and communications.

 Major benefits of proposed project include improved manufacturing methods, water purification systems, energy conversions, physical enhancement, Nano medicine, better food production methods and large-scale infrastructure auto-fabrication.

 The proposed project will provide technical hand and time saving in analysis of different prototype products for the development in industry. The proposed centre will serve as a technical hub for analysis of samples, new generation of products and man power skill development.

 It will also provide a platform to young researchers to undertake productive work and innovation in teaching, research & development.

 Economic Benefits:  Using the newly developed Nano materials and Nano structured thin film based devices, entrepreneurs may be able to start, new industrial set ups (small scale) for e.g. Nano clays, Carbon Nano tubes, Nano fibers in rubber industries, Nanostructured thin films & devices in Nano sensors, memory devices and resistive switching devices.

 The proposed centre will undertake all types of data analysis, characterization and new proto-type development activities for various industries of the State. It will create bridge between academic research & industry.

54 Gujarat State Higher Education Plan 2015-16

 New research and collaborations will bring economic benefit to the university in terms of revenue generation by patents sharing, technology transfer, training to the industry persons, contract work, data analysis, sample characterization etc.

 New Knowledge Creation:  The Centre of Excellence for Nano Science & Nano technology was established by GUJCOST at Saurashtra University in year 2005. The faculty members of Saurashtra University (Departments of Physics, Chemistry, Pharmaceutical Sciences) and Gujarat University (Departments of Physics, Chemistry etc.) are engaged in Nanoscience and Advanced Materials research since 20+ years.

 Based on the research and development work in proposed project, Government of Gujarat identified Saurashtra University to establish a new Department of Nanoscience and Advanced materials. Under this new department FIVE years integrated course in M.Sc. (Applied Physics) will start from year 2016.

 The proposed project will identify new areas of learning, interaction with industries and young students of the Gujarat state will get benefit in their careers. Also, industry & academic collaboration will be established in research & developmental work.

 The sophisticated instruments proposed in this proposal, will provide young researchers with new kind of learning, expertise and analysis etc.

 By organizing workshop/seminar on regular basis under the proposed project, it will be possible to the exposure for interaction within the state & with experts from National level in the said field.

 The student & faculty exchange program will serve for creation of new knowledge within the state and National level in the field of Nano Science and advanced materials.

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10. Research and Innovation culture creation among affiliated colleges

 We have research guides and researchers from affiliated colleges also. The proposed multi- disciplinary integrated advanced research centre will act as a catalyst and facilitator for promotion of research and innovation culture among them through training and consultancy, facility of advanced experiments and result analysis.

 The proposed project will be useful to 400+ affiliated colleges and also 50+ PG center running under Saurashtra University. Presently, our major instrumental facilities in various departments are regularly utilized by research supervisors of different affiliated colleges. Also, the registered Ph.D. students are using experimental facility based on user demand system. The proposed project will be implemented in a common building: central instrument facility (CIF) under RUSA and it will be providing more encouragement to affiliate colleges and PG centers, also.

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Annexure: 6 Proposal

Interdisciplinary Research in life science and integrated Teaching in Cell and Molecular Biology (Under RUSA Component 8)

At

The Maharaja Sayajirao University of Baroda Vadodara

Submitted to Knowledge Consortium of Gujarat Ahmedabad 2015

57 Gujarat State Higher Education Plan 2015-16

PROFILE

Name: The Maharaja Sayajirao University of Baroda

Address: Fatehgunj, Vadodara- 390002, Gujarat

Website: www.msubaroda.ac.in

Vice Chancellor: Prof. Parimal H Vyas

(Acting Vice Chancellor & Pro Vice Chancellor)

Phone: 0265-2795600

Registrar: Dr. Neerja Jaiswal, Officer on Special Duty

Phone: 0265-2795521

Date of Establishment 30-4-1949

No. of Affiliated Colleges Nil

No. of University Dept.: 90

No. of Faculties/ Colleges: 13 Faculties, 3 Colleges and 1 Institute

Status of the University: Residential

Total No. of Students: 35,000

Campus Area: 275 Acres

Nodal officer: Prof. Sarita Gupta, Coordinator, Dr. Vikram Sarabhai Institute of Cell & Molecular Biology

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Checklist of parameters for Research and Innovations (Component 8)

Part A (Theoretical Aspects)

1. Outcome and focus area of research proposal: Interdisciplinary research in life science and integrated teaching in cell and molecular biology . Faculty of Science, of M.S University had initiated innovative academic programme for interdisciplinary life science research and integrated teaching “Five year integrated teaching program of M.Sc. in Cell and Molecular Biology” wherein various departments of the faculty participate in joint coordination for innovative teaching and research in varied fields of life science such as stem cell research, drug discovery and host-microbe interactions. Present proposal is further extension in the same area of research to understand disease pathogenesis. Life science research and education has been growing and recently understanding life related processes at cellular and molecular level is the prime area of research. Stem cell provides excellent platform for understanding their role in disease pathogenesis, and their application for cell based therapies. The present proposal is focusing on designing novel therapeutics, drug delivery system, cell based therapy for some of the important disease of GUJARAT like Diabetes, Cancer, Vitiligo etc in an interdisciplinary manner. Another subarea will be plant microbe interaction to understand their role in ecosystem. Integrated teaching programme is very unique, which provide excellent training in cell and molecular biology. Summer training and project work will be imparting excellent training in house and at various national and international institutes to produce well trained excellent manpower to cater the needs of future research. Thus, the major objective(s) are --- 1. Interdisciplinary research in life sciences with special emphasis on disease pathogenesis, stem cell and novel drug design and delivery systems and plant microbe interaction . 2. To promote interdisciplinary teaching especially for 5 year integrated M.Sc programme in Cell and molecular Biology. 3. To provide skill development training through summer training, minor research projects, seminars, workshops to enhance employability of students and faculty development.

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4. To undertake extension activities promoting social development through public private partnership.

2. Scalability and Sustainability of the project proposal ;

The M.S. University of Baroda is an amalgamation of 13 different Faculties with 90 associated Departments providing an in-house expertise in almost all major disciplines of science and humanities. With this advent a unique interdisciplinary programme in advanced research and integrated teaching was successfully executed since 2010-2015, wherein, various participating departments commenced innovative scientific research to achieve milestones and provide a scientific depth of knowledge and beneficiary outcome to human kind. Integrated M.Sc. in Cell and Molecular Biology commenced with a virtue of uniting the knowledge from all the scientific disciplines with a vision to develop young, bright, dynamic versatile Indian scientists. The innovative interdisciplinary research and integrated teaching programme started by the university is the benchmark profile of the university. For sustainability, expansion of the scientific notion obtained from the outcome of the 5 year project, continuous remodelling and up-gradation of the scientific aids including sophisticated high end scientific equipments, skilled manpower, resources, consumables etc are needed. Appreciable numbers of national and international scientists visit every year to impart knowledge and strengthen the scientific and technical expertise to the student, faculties, PhD students and young researchers. This curriculum needs to be strengthened in order to initiate international collaborations and exchange programmes by inviting more number of national and international visiting scientists. This would help in converting the existing facility into state of art facility and a unique platform for innovative interdisciplinary research and integrated teaching. Activities such as skill development training for enhanced employability and extension activities promoting social development will contribute towards the sustainability of the institute.

3. Prioritization of the area of research done by the state and why Gujarat is a regionally versatile state with variations in folks, feed, economy and industrialization. Extrinsic factors like environmental pollutants, industrialization, modernization, fat diet consumptions, sedentary life style have affected the health of the population residing in the state. Various diseases like obesity mediated diabetes, cardiovascular

60 Gujarat State Higher Education Plan 2015-16

diseases, male and female infertility, neurodegenerative diseases, many kinds of cancer are profoundly found occurring in the population. Stem cells are investigated extensively as therapeutics and a cellular model for understanding disease pathogenesis. MSU is active in stem cell research for regenerative medicine and its applicability in amelioration of diseases like diabetes, infertility, cancer, BPH etc. Bioactives obtained from plant and microbes are being explored as safe and promising therapeutics. Efforts are being made to understand effects and molecular mechanisms of various environmental disruptors and pollutants that cause diseases like vitiligo, reproductive disorders etc. Cellular and molecular approaches towards occurrence of disease pathogenesis and their amelioration are of prime interest in current research areas. Several nano-formulations targeting various prevalent diseases are being designed in order to suffice the need of novel drug delivery systems. Extensive research in this area is being carried out by pharmacy department of the university to identify efficient drug delivery systems including gene therapy for cancers, neurodegenerative diseases and metabolic diseases. Microbial systems are being exploited at a great extent to understand disease pathogenesis, molecular mechanism for drug resistance, plant microbe interactions for providing better and effective agriculture products. Various GMOs are being constructed for producing beneficiary agricultural products, reduce antibiotic resistance and virulence. Biotechnology is being extensively explored for better plant cultivation with an advent of plant tissue culture techniques. However, Gujarat is still lacking behind in research compared to other states. Moreover, there are no national level institutes in area of life science in our state. For accomplishment of this moto, the state needs to expand the existing research to excel in this relevant field.

4.Quality of the institution and (NAAC grade) and faculty undertaking the research-

The Maharaja Sayajirao University of Baroda is a premier university in the state established in 1949. It has 13 Faculties, 90 Departments, 8 Specialized Centers and 3 Colleges with 1112 teaching staff. In recent times, the University has taken initiatives for promoting research, teaching, training and consultancy in thrust areas. The M. S. University has been NAAC reaccredited ‘B’ Grade with CGPA 2.71in 2010 and undertaking all the steps for reaccreditation.

Academicians at the University have a large number of publications to their credit. It is commendable that 57% of all publications during 2010-2014 are interdisciplinary in

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nature. The all time H-index of the University is 56. , University received 285 major research projects with funding of about Rs. 110 crore between the years 2011-2015 funded by UGC, DST, DBT, CSIR, ICSSR, DAE, MOE, UNDST-TIFAC, GUJCOST, DST etc.

Faculty of science has 12 departments; most of them are UGC DRS or DST FIST sponsored departments. 185 PhD were awarded in science during 2010-2015. Faculty members have high research credential and based on high H index, DST purse granted worth of 9 crores in 2009. Further, DBT supported interdisciplinary life-science research and education programme in 2010 by providing grant of 13 crores for establishing high-end equipments facility and for undertaking modern research in life science. Above grant enabled us to establish a unique state of art facility known as “Dr. Vikram Sarabhai Institute of Cell and molecular Biology” for integrated teaching and interdisciplinary research. Remarkable increase in quality and quantity of peer reviewed research articles could be achieved and faculty members could get large number of projects from various national level funding agencies PhD students and faculty members also won several awards at various national and international conferences. Also a unique programme of 5 year integrated MSc in cell and molecular biology has been initiated in 2012 in honor of Nobel laureate Prof. Venkatraman Ramkrishanan, an explicit example for interdisciplinary research which got high level reorganization not only at national but also at international level.

5. Accountability of the project

The Vice Chancellor and the Pro Vice Chancellor of the university will be the administrative as well as academic heads. The responsibility of the smooth and proper functioning of the project will be entrusted upon the Registrar of the university, and the Coordinator/nodal officer of the project. The academic and research output and monitoring will be the responsibility of all principal investigators and faculty members participating in research and teaching.

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6. Phases/ implementation milestones and plan of action in 2015-16 and 16-17

2015-2016 16-17 17-18 18-19 19-20 Procedures for Installations and Hands on To include these Collaborations purchase of new training to the technical and instruments as with various equipment specific recruited applications part of central national and staff, based training instrumentation international demonstrations through facility/ center of Research to the research workshops to the excellence. institutes, students, young researchers and Continuous industries. faculties young faculties monitoring and Outcome of from various maintenance of research will parts of India. the instruments. translated for the Research articles Intended to sign benefit of will be published MOUs between mankind. in reputed universities, Commercialization journals. research and technology institutes and transfer will be industries. developed. Patents will be filed

All scientific and Imparted Workshop, Workshop, Workshop, technical training for their trainings and trainings and trainings and skill manpower will respective skill development skill development development of the be recruited responsibilities of the recruited of the recruited recruited manpower. manpower. manpower.

8. Financial resources, financial plan and financial sustainability

Dr. Vikram Sarabhai Institute of Cell and Molecular Biology is sustained to date by financial assistance from DBT, New Delhi and Government of Gujarat. However, the great grant received from DBT is completely utilized and currently there is minimum financial support.

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The budget proposed in this project would provide financial aid for the maintenance and up- gradation of the existing central instrumentation facility. New major and minor equipments will be purchased necessary for high-end research. The institute has hardly any employed manpower to successfully execute interdisciplinary research and integrated teaching. Scientific and academic staff recruitment is necessary for successful execution of integrated teaching and technical officers are required for operating high end instruments and providing their expertise to the researchers for their data acquisition and analysis. Program officers are required to execute functionality of the instrument by maintaining financial records and protocols and to undertake administrative work.

Financial Budget

1st Year 2nd year 3rd year 4th year 5th year Total (crore) Items Non-recurring grant

A. Vertical/horizontal 2.5 2.5 extension of Dr. Vikram Sarabhai Institute of cell and Molecular biology for research laboratories, equipment rooms. and campus development 0.05 0.05 i. development of library facility ii. development of computer 0.15 0.15 facility and video calling facilities

B. Non-recurring (central facility)

1. New Equipments Purchase 17.38 17.38 (Table-1A) a. Major Equipments b. Minor Equipments

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2. Upgradation of Existing Instruments(Table-1B) 3.92 3.92 3. Upgradation of existing and new research laboratories(Table-1C) 0.65 0.65

Sub-Total (A)+(B) 24.65

C. Recurring Grant

Manpower ( Table -1D) 8.02 8.02

Annual maintenance charges 1.95 1.95 for existing instruments

( Table – 1 E)

Consumables 0.30 0.30 0.30 0.30 0.30 1.50

Laboratory Training and 0.05 0.05 0.05 0.05 0.05 0.25 Workshops

Travel Support & (National & 0.10 0.10 0.10 0.10 0.10 0.50 International ) meetings etc

Outsourcing of scientific 0.20 0.20 0.20 0.20 0.20 1.00 experiments and allied work

Overheads Charges 0.15 0.15 0.15 0.15 0.15 0.75

Grant for publication/ patent 0.20 0.20 0.20 0.20 0.20 1.00 charges

Other Expenses 0.10 0.10 0.10 0.10 0.10 0.5

Sub-Total (C) 3.094 3.094 3.094 3.094 3.094 15.47

Total (A+B+C) 8.024 8.024 8.024 8.024 8.024 40.12

Total Budget: forty crores and twelve lacs only : 40, 12, 00,000/- INR Note -Annexure –Table A to E with detailed information

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9. Quality improvement/gap filling projections:

It is a fact that the state of Gujarat in general and the M. S. University of Baroda provides excellent rudiments for basic science and technology-related research. But what is lacking is a common platform where all the departments of science faculty and pharmacy adjoin and carry out innovative interdisciplinary research and integrated teaching in life sciences. The development of the institute with these visions have improved the quality of research and teaching by constructing a bridge between conventional mode of theory based scientific studies and research based scientific studies. Courses at the institute contribute towards advancing the quality of education through innovative support systems and knowledge dissemination. The Institute of Interdisciplinary Studies fills in this gap and provide a considerable expertise in a multi- and interdisciplinary approach to technology in-house. The activities of the proposed institute are also projected to bridge the existing gaps between a student and his professional career, research and outreach and science and society.

10. Evidence/plan of academic- industry partnership:

The central instrumentation facility established is appreciably used by industries of Gujarat for carrying out their research and data analysis work. Large scale industries and the budding industries are enormously willing to collaborate with the institute to execute research projects, industrial training. The students of 5 Year Integrated M.Sc in Cell and Molecular Biology has been provided summer research training by various industries of Gujarat. Futuristic plans are in pipeline to come out with various advantageous projects drawn in favour of societal benefit and proliferation the progress of research and academics.

11. Promotion of innovation:

The institute will be committed more to encourage and support innovative research ideas, outreach activities and technological interventions. A novel and truly interdisciplinary initiative will be prioritized. Innovative methods for teaching mainly related to hands- on experiences and self sustainability will be promoted. Seminars and workshops to cultivate innovative thinking in the students are proposed.

12. Manpower augmentation/recruitment or engagement of highly qualified researchers - Wherever Applicable: The institute is a hub of interdisciplinary research and integrated teaching in field of life sciences. Limited contractual manpower is available in the institute to run these extensive

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programmes. It is mandatory to recruit more skilled scientific and technical staff for sustained and better performance of research activities. Skilled scientists and technically expert personals are required to run and maintain the functionality of the institute at a better level in order to convert it to a state of art facility and internationally recognized research institute. The scientist of various institutes at national and international level already recognized the potential of research and 5 year integrated teaching and willing to participate as visiting faculty programme and provide excellent research training to students. The financial budget would be beneficiary for employing various categorical employments and for student /faculty exchange programme.

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Part B 1. Existing body of research work in that area: Faculty of science at M. S. University is an existing body for interdisciplinary research in discipline of life science. Three major areas were identified in last five years - stem cell research and molecular pathogenesis of diseases, drug delivery systems and plant microbe interaction. Excellent progress has been demonstrated in the area of cellular and molecular basis of diseases and designing differentiation protocols for cell therapy and novel drug delivery system, based on progress it is desirable to further strengthen these areas proposed in the present proposal.

2. Rationale and significance:

Proposed proposal has been made with an intension to expand the collaborative research and education running through financial aid. The need arises for sustaining the already well established central instrumentation facility and its up-gradation and installing various other necessary instruments which will elevate the research output . The funds are required for smooth running of the 5 Yr. Integrated M.Sc. in Cell and Molecular Biology and successfully establishing effective summer research training for the students of this course. Funds are required to provide monthly emoluments to the staff, travel, honorarium and hospitality to various national and international faculties and scientists participating in research and education of this institute. 3. Credibility of persons involved: In the last five years the grant received from DBT for interdisciplinary research aided high end instruments due to which the level of research has increased and many international peer reviewed research papers were published by the faculty members of faculty of science. During this period, team leaders were successful to initiate various research projects. Number of research articles increased annually and more than 50% of the articles published in the last 5 years are of interdisciplinary nature. The coordinators of the activities at the Institute and the research team are experienced researchers, possessing fine academic credentials with good citations and appreciable h-index with good national and international collaborations. Number of PhD students also increased reasonably. Gujarat academy of sciences in 2015 judged two PhD student’s thesis as best thesis amongst many from various universities of Gujarat. Also faculty members especially from

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pharmacy departments filed several patents. This signifies that the researchers and faculties at the M. S. University of Baroda are up to date and in tune with the need of the hour.

4 .Definition and significance of research outputs/deliverables: The opportunities that would be provided from the proposed project will help to strengthen state of art institute in the area of life science with interdisciplinary approach .The project would provide employment to eligible candidates for various scientific and non-scientific posts in order to smoothly run the institute. The research output will attain better heights by utilizing the high end equipments, would provide even more opportunities for collaborations with various national institutes, international institutes and industries. The students taking education from the 5 Year Integrated M.Sc in Cell and Molecular Biology course would grab better opportunities into premier research institutes and industries as novel scientists and researchers. The research findings of the interdisciplinary projects taken up under the Institute will be published in high impact factor journals. Innovations in technologies will be registered as patents, technology transfer of generated knowledge, commercialization of innovative products will be translated to the society through the extension activities. Symposia, seminar and workshops will enhance the interaction between researchers and will help in faculty development.

5. Clarity of aims, objectives and research questions: The project is designed for undertaking research broadly in three aspects:

1. Stem Cell Research and Disease Pathogenesis. 2. Drug delivery systems 3. Host-Microbe interaction

Research Group I. Stem Cell Research and Disease pathogenesis

Several extrinsic and intrinsic factors like environmental pollutants, sedentary life style, dietery habits, inflammation, hyperinsulinemia, hyperglycemia and several genetic factors are responsible for occurrence of various cellular and metabolic diseases. Cytokines mediate systemic or localized inflammations are the major contributory factors in disease pathogenesis. Various transcriptional factors, miRNAs, DNA interacting protein like PARP-1, neuropeptides,

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neurotransmitters and other growth factors, ubiquitin mediated proteasomal degradation etc. play extensive regulatory roles in body homeostasis and occurrence of diseases. Crosstalks in various signalling pathways are studied to understand disease pathogenesis with concomitant identification of molecular targets for treating diseases and for new drug formulations.

In last decade enormous stem cell research is being carried out in understanding the sequel of disease pathogenesis. Discovery of incredible potentials of stem cells to differentiate into multiple cell types proved as a boon in amelioration of various diseases like neurodegenerative diseases, diabetes, cancer, vitiligo etc. Embroyonic stem cells, adult stem cells, induced pleuripotent stem cells are capable of differentiating in desired cell type like islets, adipocytes, neurons, skin, muscles etc. depending upon the growth factors and micro environment provided to them. Mesenchymal stem cells derived from adult tissues like adipose tissue, bone marrow, hair, skin and dental pulp are widely implicated in regenerative medicine due to their pluripotent or multipotent and non-immunogenic nature. These stem cells are now identified to cross talk with several cell types by means of cytoskeletal reorganization, tissue remodeling and replenishing diminished cellular micro environments to repair cellular and metabolic dysregulations. Apart from stem cells, various therapeutic like bio-actives produced by microbes and plants have differentiation and disease amelioration potentials.

Apart from stem cells being potential candidate for cell therapy, they are also found to play role in several disease conditions like obesity and diabetes and neurodegenerative diseases. Further exploration is required for understanding the molecular mechanisms behind their dysfunctionality. Several key questions are raised and objectives are designed to understand the development of cellular and molecular complexity leading to disease pathogenesis and expeditions needs to be done to mitigate disease pathogenesis as an approach of regenerative medicine and also to mitigate the best potential of these cells for the therapeutic intervention.

A. Stem cells - Diabetes and obesity and Neuro-muscular disorders. 1. To explore Human BMSCs and ADSCs in islet differentiation and Identification of key miRNAs, crucial genes interacting with PARP-1and impact of various cytokines and myokoines to increase islet neogenesis and its longevity for better therapeutic efficacy in diabetes an important disease of Gujarat. (Prof. Sarita Gupta, Department of Biochemistry).

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2. Generation of human pluripotent stem cells (hiPSCs) from skin fibroblast and their differentiation and impact of different cytokines (TNF-α, IL-1β, IFN-γ IL-2, IL-6, IL-10 etc.) on proliferation and functioning of β cells. (Dr. Ravi Vijayvargia, Department of Biochemistry) 3. Exploring the fate of ADSCs and neural stem cell in insulin resistant condition in peripheral tissues and brain: Implications of Insulin sensitizers in cytokine mediated insulin resistance condition associated with diabetic complications. (Prof. Sarita Gupta, Department of Biochemistry) 4. To explore the potential of probiotic E. coli in on intestinal L cells and differentiation of adipocyte subtypes white, brown and beige cells. (Prof. G. Nareshkumar, Department of Biochemistry) 5. Oligodendrocyte progenitor cell migration and role of PDGFRα - αvβ1 interactions, its role in Integrin switching and role of lipid rafts : impact on Demylinating Disorders (Dr.PrakashPillai, Dept of Zoology) 6. Enrich medium for myoblast culture to acquire muscle cell line and Induce MD in the myoblast cells by antibody blockade of muscle α- dystroglycan-laminin complex (Dr. Suresh B, Department of Zoology). B Stem cells and Cancer

1. To modulate the MSC recruitment and it signature inflammatory cytokines to induce cell death in breast cancer through exosomal miRNA (Dr. Rajesh Singh, Dept of Biochem)

2.To characterize transdifferentiation of AT-II cells to AT-I cells and role of NRG-1 in lung cancer. (Dr.VihasVasu, Department of Zoogy)

3.To elucidate the role BPH derived pluripotent stem cells in BPH and prostate cancer pathogenesis. (Prof.Sarita Gupta,Depat. Of Biochemistry) 4. To understand mutant forms of ubiquitin and other protein interactions and effect of these mutants on cancerous cell lines.(Prof. C. Ratnaprabha, Departmentof Biochemistry)

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C. Vitligo

1. Isolation and characterization of hair follicle stem cells from human hair and their mRNA and miRNA profiling (vitiligo patients and controls)( Prof. R. Begum, Dept of Biochemistry). 2. Estimation of plasma Hcy levels in Gujarat vitiligo patients and controls, monitoring Hcy induced ER stress markers and ER stress induced pro-inflammatory cytokines IL6 and IL8 in G361 cells and/or NHM.( Prof. R. Begum, Dept of Biochemistry) 3. To study the dose dependent effect of IL1α on growth, proliferation, death, and its receptor activation of in vitro cultured NHM and dose-dependent effects of H2O2 with and without PARP inhibitor on G361 cells and/or NHM. (Prof. R. Begum) D. Female infertility

1. To elucidate correlation between AITD and environmental pollutant levels in Female infertility(Prof. Pushpa Robin, Dept of Biochemistry) 2. To understand the structural-functional changes during pregnancy In PCO phenotype and role of neurosteroid –GnRH interaction and their modulations by phytocomponents of Aloe vera gel (Dr.Laxmipriya N, Department of Biochemistry). 3. Exploring stemness of granulosa cells from follicular fluid aspirates from human PCOS samples and its application in infertility. (Prof. Sarita Gupta)

Research Group II: Drug design and delivery research Group Nano-medicine in the recent advanced arena has proved to be an effective drug therapy. Various nano-formulations and novel drug delivery systems are the major areas of research in order to provide better therapeutics against conventional therapies to treat various diseases like cancers, metabolic syndrome, diabetes etc. Nano-sized drug delivery systems including gene therapy (siRNAmediated), nanoparticles, liposomes and micelles, can be investigated as carriers for treatment of various diseases. Thus, the following objectives are designed to design new formulations.

1. The prime objective of the study is to formulate Nano constructs of therapeutic gene to improve efficacy and to decrease toxicity by developing targeted drug delivery system for treatment of atherosclerosis (Prof. A.N. Misra, Pharmacy Dept)

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2. A gene delivery approach for treatment of drug resistant non-small cell lung cancer” (Prof. A.N. Misra) 3. Development of galactosylated PLGA nanoparticles, various other nanocarriers such as liposomes, solid lipid nanoparticles etc will be developed and evaluated for their liver targeting efficiency, pharmacokinetic profiles and their ability to reduce the toxicity (Dr. Hetal Thakkar , Pharmacy Dept) 4. Development of Nano-formulations to treat Metabolic Syndrome more effectively and novel Formulations for Biotechnological products for Cancer Therapy (Ms.Hemal T Tandel , Pharmacy Dept). 5. Formulation and Evaluation of Brain Targeted Nano-constructs (Ms.Hemal T Tandel) 6. Design and fabrication of mesoporous silica nanoparticles for targeted delivery of anticancer agent. (Dr. KrutikaSawant , Pharmacy Dept) 7. Development and characterization of lipid based nano drug delivery systems for some poorly bioavailable drugs ( Dr.Krutika K. Sawant ). 8. Nanoformulations of bioactive compounds isolated from Enicostemmalittorale (EL) blume for better efficacy in diabetes and efficient delivery system for cell based therapy. (Prof. Sarita Gupta, Dept of Biochemistry).

Research Group III - Plant-microbe interactions Plants are challenged by varieties of biotic and abiotic stresses which, result in serious losses agricultural products. Understanding and combating these stresses by bio-friendly approaches are an integral part of sustainable agriculture. Species belonging to the same family and even same genus differ in their adaptive approach towards the changing environment. In due course of time, some of these species become rare and endangered while others expand and function as widely distributed species. Mechanistic processes for these differential responses have not been thoroughly understood. Evaluating the adaptive and non-adaptive approaches of some of the species of Genus Ipomoea towards changing environment is an important area of study. The group will focus on different aspects of pathogenic, symbiotic and associative interactions of microbes with plants and with the environmental stresses.

1. Endophytic bacteria: colonization mechanisms and induction of defence response (Prof. G. Archana, Department of Microbiology)

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2. Role of quorum sensing in nodulation by pigeon pea rhizobia (Prof. G. Archana,) 3. Management of Bacterial Leaf Blight Disease in Rice caused by Xanthomonasoryzaepv. oryzae with endophytic Bacterial Consortia from Grasses (Prof. AnuradhaNerurkar, Department of Microbiology) 4. Bioactive compounds from endophytes of medicinal plants (Prof. S. Ingle, Department of Microbiology) 5. Development of economically viable formulation of bioinsecticide for the control of agriculturally important pests and to increase the activity of Bt toxin by genetic manipulation (Prof. S. Ingle). 6. Phylogenetic identification and virulence factors of plant pathogenic Fusariumsolani (Dr. D. Gajjar, Department of Microbiology 7. Evaluating the adaptive approach of few species of genus Ipomoea towards changing environment: miRNA proposition (Prof. N.S.R. Krishnayya, Department of Botany) 8. Molecular characterization of candidate cell death regulators during biotic stresses in plants (Dr. Sunil Singh, Department of Botany) 6. Methodology - innovativeness/originality and soundness/rigour

Novel technologies will be applied for carrying out high end research. Methodology has been developed by collaborative research projects, introduction of students and faculty exchange program, research and industrial training. Demonstrations, training programmes and workshops are being conducted.

7. Definition and significance/ value of concrete outcomes: Since the institute aims to support innovative and interdisciplinary research projects, more numbers of students are expected to be motivated to pursue their PhD or further post doctoral research. This will definitely add up to the existing talent pool of the University in particular and the state/nation in a broad way. High definition and interdisciplinary research will find more takers in the international academic and research community and thus, good publications in high impact factor journals. The main aim of the Institute is to bridge the gap between a graduate/ post graduate student by providing excellent research training and a job ready professional.

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8. Inter- disciplinary/ multi-disciplinary orientation and multi-institution networking:

Dr. Vikram Sarabhai Institute of Cell and Molecular Biology is a hub for interdisciplinary research and teaching. Various high end instruments have helped us in attracting many industries. Efforts have been initiated for various collaborations with industries and many national and international research institutes. Many scientist from various national and international institutes visited, interacted with the faculties and the students and showed great interest in signing MOU’s for effective collaborations. The present grant will help in establishing multi-institutional networking and better industrial partnership.

9. Anticipated Outcome (s) of the proposal

Societal benefit: by the aid of the proposal the society will be benefitted by getting better treatments towards various diseases. Research would help in understanding and thus eradicating fatal diseases. People would be benefitted by novel outcomes given by researchers in the field of agriculture. Economic Benefits: The project would provide a horizon for opening a bio-incubator where various young and dynamic entrepreneurs would be benefitted. The money will be generated by bio-incubator centers. Various individuals would be employed in this project. The students passing with advent of the high end research and integrated teaching would be novel Indian scientists who would be recruited in top research, academic institutes and industries throughout the world.

New Knowledge Creation: The interdisciplinary research and teaching programs undertaken at the Institute will enhance the existing knowledge base and create novel, innovative and socially useful information. The proposed fellowships to promising researchers will also motivate the students to be academically oriented. Innovative ideas may be conceived through repeated deliberations and workshops by experts from various places and inculcate research based learning both for faculty and students and thus create highly competitive environment in higher education system.

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10 Research and Innovation culture creation among affiliated colleges:

The university is affiliated to very few colleges; however the central instrumentation facility is utilized by various colleges of the state currently. Also research training programmes are being imparted to the research students and faculties of other colleges. Various skilled and senior faculties deliver scientific lectures and conduct faculty recharge programme for the faculties of other colleges of the state. The institute will also benefit undergraduate studies and high school studies. Teachers and students of various levels would be given training and their skills will be developed by hands on workshops.

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Annexure

Table I A

New Equipments for Central Instrument Facility

A. Major Equipments Sr No Name of Instruments Number Cost in Crores

1 MALDI- TOF 1 5.00

2 HPCL with PDA Detector and Auto sampler 1 0.40

3 Animal Imaging System 1 2.00

4 Centrifuge with Temperature control 1 0.10

5 Seahorse Bioanalyzer 1 0.06

6 Circular Dichroism 1 2.0

7 Cryo-Transmission Electron Microscope 1 4.0

8 Cryo-Differential Scanning Calorimetry 1 0.30

9 Controlled Stress Rheometer 1 0.13

10 Atomic force microscopy 1 0.20

11 Next Generation sequencer 1 2.0

12 Gas chromatography instrument 0.10

13 Precise Controlled Globe Box 0.15

Total (A) 16.44

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B. Minor Equipments

14 Table Top Centrifuge (3) 0.10

15 Balance (Fine and core) 0.010

16 PCR Machine (3) 0.10

UV Spectrophotometer (3)+ 17 spectrophotometers and autoanalyser 0.12

18 Upright + wet lens(100 x)for Microscope 0.04

19 Phase contrast inverted microscopes 0.05

20 Binocular Microscope ( students grade) 0.02

21 Deep freezer (-80°C) (3) 0.2

22 Deep freezer (-20°C) (3) 0.01

pH meter(2), centrifuge and magnetic stirrer 23 (2), autoclave(2) 0.03

24 Refractometer 0.05

25 Biosafety cabinets (2) 0.05

26 Students Binocular microscopes (20) 0.06

Water bath with variable temperatures (2), 27 Incubator (2) 0.02

Potential state/ Galvanic state for cyclic 28 voltmeter 0.08

Total (B) 0.94

Total of A+B= 16.44+0.94 17.38

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Table I B

Up-gradation of Existing Instruments

Sr No Name of Instrument Cost in Crores (INR)

Upgradation to latest super resolution confocal microscope. New super resolution microscope 1 Confocal microscope LSM 710 1.20 costs approx 5.5 crore INR

2 FACS ARIA III 0.50 Purchase of new lasers and filters

Purchase of Open Array system 3 Real Time PCR QUANT STUDIO 0.20

Software+ Scanner 4 2D Gel Electrophoresis 0.75

Various accessories 5 LCMS/MS 0.50

(filters for absorbance+ 6 Multi Mode Reader 0.02 fluorescence+ bioluminescence)

7 Central Air Conditioning system 0.50

8 Insurance of the instruments 0.25

Total 3.92

Annexure I C

Upgradation of existing and new research laboratories

Sr No Particulars Amount in Crores

1 Modular Furniture for Laboratories 0.30

2 Accessories for high end equipments 0.15

3 Facility for Transgenic Animals 0.20

Total Amount 0.65

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Table – 1 D

Manpower

Sr No Manpower 1st Year 2nd Year 3rd Year 4th Year 5th Year Total

Contractual Teaching Assistants/ 12,00,00,0 1 24,00,000 24,00,000 24,00,000 24,00,000 24,00,000 Scientist 0 (5) (40000/per head/ month)

Resarch Associate 2 (10) (35000/per 42,00,000 42,00,000 42,00,000 42,00,000 42,00,000 21,000,000 head/ month)

SRF 3 (10)(33600/per 40,32,000 40,32,000 40,32,000 40,32,000 40,32,000 20,160,000 head/ month)

Technical Officers (RESEARCH) 1,15,20,00 4 23,04,000 23,04,000 23,04,000 23,04,000 23,04,000 (06) (32000/per 0 head/ month)

Fellowships for Student/ faculty 5 8,00,000 8,00,000 8,00,000 8,00,000 8,00,000 40,00,000 exchange programme

Laboratory Assistants (5) 6 1,00,000 100,000 100,000 100,000. 100,000 500,000 (20000/ head/ month)

Summer Research Training student 7 9,00,000 9,00,000 9,00,000 9,00,000 9,00,000 45,00,000 fellowship (90) (10000/head/yr)

Honorarium & 8 Accomodation for 3,50,000 3,50,000 3,50,000 350,000 350,000 17,50,000 Visiting Scientists

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Sr No Manpower 1st Year 2nd Year 3rd Year 4th Year 5th Year Total

Program officers 9 9,00,000 9,00,000 9,00,000 9,00,000 9,00,000 45,00,000 (25000 p.m.x3)

Honorarium

( nodal officer/ 10 director/ 60000 60000 60000 60000 60000 300000 coordinator

(5000 p.m X 1)

16,046,00 16,046,00 16,046,000 16,046,000 16,046,000 80,230,000 0 0

Total (eight crore two lacs thirty thousand only)

Annexure I E

Annual Maintenance Charges for Existing Instruments

Sr 1st Year 2nd Year 3rd Year 4th Year 5th Year No Name of Instrument Total

Confocal microscope 1 LSM -710 900,000 900,000 900,000 900,000 900,000 4,500,000

2 FACS ARIA III 900,000 900,000 900,000 900,000 900,000 4,500,000

Real Time PCR 3 QUANT STUDIO 900,000 900,000 900,000 900,000 900,000 4,500,000

2D Gel 4 Electrophoresis 300,000 300,000 300,000 300,000 300,000 1,500,000

5 LCMS/MS 500,000 500,000 500,000 500,000 500,000 2,500,000

6 Multi Mode Reader 200,000 200,000 200,000 200,000 200,000 1,000,000

7 HPLC 200,000 200,000 200,000 200,000 200,000 1,000,000

Total 19,500,000

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Annexure: 7 Research Proposal submitted to MHRD-RUSA for Climate Change Impacts Studies on Shoreline Diversity of Gujarat

Submitted by:

Gujarat University, Ahmedabad-380 009, India

January-2016

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Part-A

Networking Universities

Saurashtra University, Rajkot S. P. University, Vallabh Vidyanagar M. K. Bhavnagar University M. S. University of Baroda, Vadodara Hemchandracharya North Gujarat University, Patan

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Study Context

The state of Gujarat is located between 20° 6’ N to 24 ° 42’N and 68° 10’ E latitude to 74° 28’ E longitude. Gujarat shares its international boundary with the country of on the North West side. It is bounded by the Arabian Sea in the west, by the state of in the north – north east, by in the east and by in the south – south east and the Union territories of Diu, Daman, Dadra and Nagar Haveli in the south. The state also has the longest coastline in the country measuring about 1,600 km along western parts of India, extending from Lakhpat in north to Valsad in South.

Gujarat is only state of the country having two gulfs viz Gulf of Kuchchh and Gulf of Khambhat which provides opportunities of trade through sea. State coast is distinct from the other coasts with shallow depth, wider continental shelf and vast stretches of saline and tidal mudflat. The longest coastline is approximately 21% of the entire Indian coastline. It has been broadly divided into four geomorphologic and oceanographically distinct sub regions. The entire Gujarat coast has been broadly divided into five distinct but interconnected regions. These include, (i) Gulf of Kachchh, (ii) Gulf of Cambay, (iii) Saurashtra Coast (iv) Coast and (v) Rann of Kachchh. Gulf of Kachchh (GoK) is very rich in terms of biodiversity values. The GoK support varied habitats including coral reefs, mangroves, creeks, mud flats, islands, rocky shore, sandy shore etc., which in turn provide suitable environment for wide range of flora and fauna. Of these habitats, coral reef systems are quite unique in terms of its isolation and surviving in extreme oceanographic and climatic conditions.

According to 1991 Census, about 549 villages with the total population of about one million are situated along the Gujarat coast. The longest coastline dotted with 41 ports caters to demand & supply of cargo from the nearest maritime countries like Africa, Middle East & Europe. Besides this, the entire northern India and some parts of the central India also serve as hinterland to the ports. Out of a total 142 minor and intermediate size ports, 11 and 29 are situated, respectively, on Gujarat coasts. Of the

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total 27,175 sq. km of wetland area in Gujarat, the coastal wetlands constitute 92.3%. Gujarat coastal wetlands have marine biodiversity of global to national to local significance. Importantly, these bio-diverse system act as barrier against natural calamities like storms, cyclones, strong winds etc. To protect these systems, one marine national park and four sanctuaries are also created along the coastline of Gujarat.

Ironically, all these coastal regions are facing inherent challenges of economic development and associated environmental degradation. They are vulnerable to various developmental activities including rapid industrialization and coastal infrastructure expansion projects as a part on economic development of the state. These seriously alter the land use system of the region.

In last decades utilization of costal vegetation in food (vegetables, salads, pickles), fodder, wood, bio-fuel etc assume new dimension and in spires researchers working for this highly economically potential vegetation. Marine botanists have also concentrated on various components of marine flora and fauna, which can be mainly divided in to diversity of five major groups namely phytoplankton diversity, sea grass diversity, seaweed diversity, mangrove diversity and halophytic diversity, coastal fauna, microorganisms (Kannan, 1999).

Among the various biodiversity regions, the marine and coastal zone ecosystems are of particular importance in terms of utility to human livelihood security, Costal vegetation is extremely important both for the natural recourses and ecological communities they contain as areas of concentrated human activates. Gulf of Khambhat (Cambay) wetlands is expecting to face big human activity interference due to announcement from Government of Gujarat as a Special Economic Zone (SEZ) for Chemical industries, diesel, machine tools and some petroleum based industry too at Dholera village of . This would have definite impact on the ecology of the area; it is possible that due to pressure of population, settlements to be established, by clearing and disturbing costal vegetation, increasing use of pesticides, industrial pollution

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nearby area and the ecosystem would change completely. Many areas under costal vegetation may convert into fishponds and plain salt beds like other present structure, There is an urgent need to suggest standard models for the species inventory within diversity as preventive measures with the help of established field procedure for specific purposes like statistical validation sampling design using rigorous quality control and data administrative practices through latest laboratory as well as field experimental practices.

1. Outcomes and focus area of research proposal:

The data generate after completion of this project has various societal, economical and environmental significance. The coastal ecosystem is on high pressure due to many development activities. There is an immediate requirement of action for conservation & development of highly potential environmentally sensitive areas of Gujarat Coast. There is an urgent need to improve the productivity, profitability and sustainability for farming of coastal vegetation or costal diversity for commercial purposes. They will an addition serve as carbon sinks, since they will help to enhance carbon sequestration and there by contribute to reduce the growing imbalance between carbon emissions and absorptions.

Mangroves and other coastal vegetations are very efficient in carbon sequestration. This fragile habitat is the home for many adjoining flora and fauna. Studies are required for development activities carried out at coastal area, harmful aquaculture practices (such as excessive use of chemicals and other harmful chemicals to the vegetation) that impair product quality and affect the health of consumers. Strategies should be devised for the restoration of abandoned aqua farms to their original state, the quality of wastes can be improved by appropriate changes in aquaculture technologies and the addition of waste treatment facilities in the farm layout should be considered.

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The generated data will be useful to various industries action plans, potential source of income from cultivated coastal diversity, policy makers will get idea to solve real life problems of present community at shoreline/coastal area.

The data will also be beneficial for sustainable fishing, sea weed cultivators, bio fuel from algal culture, planning and development of on shore and off shore activities, help to develop strategy for gainful utilization of saline, alkaline and waste land for industries. The data would be helpful to design strategies for shore line and mangrove protection (ways and means). The technocrats will get idea about the appropriate technology solution to get portable water from the sea. The cage culture industries get benefited to develop suitable or potential site for culture. The policies generation and model development required managing the discharge of effluent from the industrial waste and ultimately it disturbs the nearby ecosystem diversity.

Probable Outcomes with reference to Climate Change Impacts and its Management  Comprehensive document of current shoreline diversity and ecosystem status would be generated with extensive data on the physical, chemical, biological parameters, oceanographic research with RS and field survey of entire shoreline of Gujarat.  Climatic variability and its impacts on shoreline diversity would be first of its kind research for such an important coastal area of Gujarat.  Temporal and spatial distribution pattern studies, degradation or loss of habitat, information about migratory fauna in the coastal and marine environment would be addressed with scientific intervention.  Novel region specific developmental models would be developed for the shoreline flora and fauna to predict the future trend for the current ecosystem management.

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 The generated data will be useful for the future research, planning, management, regulations of human activities, market development, adoption of conservation strategies and implementation of policies.

2) Scalability and Sustainability: Five Years (2016-2021)

Gujarat University is the centre for climate studies in the since 2008. We are planning to develop a state of the art centre with national and international collaboration to address the most important phenomenon - Climate Change Impacts and its Management.

Gujarat University is actively coordinating various projects on coastal & marine biology with SAC-ISRO, MoES, State & Central Government, CII, GEER foundation, Gujarat Ecological Commission (GEC), Forest Department, National Innovation Foundation (NIF), Shrushti, Gyan for research and extension activities.

Introduction of Developmental models for Gujarat Coast:

1. Shore line diversity status model for flora and fauna (Including migratory).

2. Conservation, restoration, and management model for mangroves and its associates.

3. Commercial model for utilization of shoreline diversity and livelihood for local community in coordination with NGOs and Industries.

4. Complete document on shoreline ethnobiology, medicinal capacity and profitable, sustainable model.

Gujarat is a peninsular state of India and it is almost surrounded by the Arabian Sea on its three sides. The peninsula is traditionally known as Saurashtra. It lies on the west and is surrounded by the Arabian Sea on its three sides. Its central mass is an elevated highland with hills. The and Gir hills are most prominent. The Girnar has a high peak named Gorakhnath (1,117

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meters). The land slopes gently down towards the coast from the central mass. A narrow strip of coastal plain surrounds the peninsula.

The Kachchh peninsula is situated in the northwestern part between the Rann of Kachchh to the north and the Gulf Kachchh to the south. It is a desolated and an isolated raised platform covered with sand, sand dunes and mud-flats. Another part of the Gujarat is Rann of Kachchh. It lies on the northern and eastern parts of the Kachchh peninsula. It is marshy saline lowland covered with mud-water, sand, mud and grass. During winter the saline marshy land dries up and a thin layer of salt is left on it. Its northern part is known as the Great Rann and its eastern part is called Little Rann. All these special type of feathers make the Gujarat one of the leading industrialized states of India.

The coast of Gujarat, characterized by the estuarine stretches is geologically classified to be of submergence type (Ahmed, 1972).The shoreline of Gujarat varies from being a smooth to moderately straight. Heavy influxes of sediments are received from the major perennial rivers of south Gujarat like Purna, Ambika, and Kolak on the north side Sabarmati and Mahi etc. are draining mainly from into the Arabian Sea.

However, the coast of South Gujarat characterizes the drowned alluvial coastline (Ahmed, 1972).The wetlands of the study area comprise of intertidal mudflats, mangroves, salt marsh, sand beach, dunes, tidal creeks, etc. The lower most reaches of the river form extensive mudflats. The cross profile across the coast is made up of lower foreshore, upper foreshore, backshore/berm, Paleoridge, coastal dunes resting over the ridge, tidal flats, raised mudflats, alluvial plain and hilly terrain. The river mouths support numerous small islands (Ahmed, 1972). Tidal waters reach the mudflats through a dense creek network. It experiences semi-diurnal tides, with two high and two low tides daily.

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The coastline of the study area is sandy and shows development of inland sandy ridges parallel to the coast at places. These ridges reflect the past high sea-levels. The shoreline in this part is much dissected and replete with small estuarine creeks and lagoon, along which the tidal waters spread inland. The coast is more or less straight up to Umargaon with narrow sandy-ridge all along. The coast is rocky with narrow crescentic beaches separated by inward projecting headlands beyond Umargaon. The inter-tidal zone is made up of basaltic platform with a thin veneer or mud (Merh, 1995). Sandy beaches consist of black sand from Purna estuary to Varoli and vary from 10 – 65 m in width. High tidal mudflats are present at the mudflats of almost all the estuaries. They are composed of clay, silt and have salt encrustations as well. Intertidal mudflats occur along the mouths of all the estuaries. These mudflats are cut through by numerous tidal channels and dense creek network. In the southern part of the study area, at many places along the coast, the Deccan Trap is exposed in the form of sheet rock. Such a rock coastline is observed south of Auranga and near Umargaon rocky (Kulkarni, 1985, Anonymoys, 2014).

Table-1. Area Distribution of Two Gulfs Ecological Geographic Site Area in km² Coastal Length Km Importance Location 131.4 (Mangrove) Mangrove 20º15' to 23º35' N 1307.8 Gulf of Kachchh 94.91 (Coral Main) Coral Reef 60º05' to 70º22' E 0406.5 75.4 (Coral Island) 22 º15'-22º 30'N 6.4 Gulf of Khambat Estuary 2.63 (Mangrove) 72º 15'-72º 30'E (Mangrove)

Potential Threats Stress on wetlands has increased due to the rapidly growing population, technological development, urbanization and economic growth. Additional

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pressures on wetlands from natural causes like subsidence, drought, hurricanes, erosion etc., and human threats coming from over exploitation, encroachment, reclamation of vast wetland areas for agriculture, commercial and residential development, and have altered the rate and nature of wetland functions particularly in the last few decades. Even though mangroves have such important values they were treated as unwanted plants used mainly as a source of timber and charcoal which caused depletion during the last two decades. Recent surveys quote that deforestation is the cause which destroyed about 44% and 26% of mangroves along the west and east coast, respectively (Upadhyay et al., 2002). This caused a critical need for understanding the biodiversity of the mangrove ecosystems. This ecosystem is a nursery for juvenile of economically important fish and prawn species. Great amount of detritus food supporting a variety of young fish and shrimps is generated from mangroves (Ingole, 2005). In private areas or khazans land mangroves face severe threat due to the conversion of these lands for aquaculture, agriculture and other developmental activities and reclamation causes damage to saplings and small mangrove plants in general.

Mangroves in India are one of the most valuable coastal habitats providing enormous benefits (both tangible and non-tangible) to the local communities as well as the ecology and environment surrounding them. Tangible benefits of mangroves comprise timber and non-timber products, fishery and other livelihood support systems whereas non-tangible benefits include ecological and social functions, such as coastal protection against wave and current abrasion, shelter and habitat for wildlife, and ecotourism. Globally, mangrove resources are seriously threatened and have been disappearing due to intensive human as well as developmental interactions. Human settlements, expansion of agricultural or salt-making lands, development of industries and ports, the expansion of coastal aquaculture, have been identified as the critical factors that

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have resulted in depletion and degeneration of mangrove resources. Mangroves need protections from natural disasters in which coastal zone is a dynamically unstable where of one or the other kind like sea intrusions, cyclones, tsunami, etc., strike year after year. Last few decades have experienced gradual increase and unusual accumulation of CO in the atmosphere mainly due to 2 industrial activities, global warming, ice melt increase in water in oceans, tidal waves.

Conservation and reforestation programmes of mangroves in the central west coast of India was initiated to increase public awareness with regards to the importance of mangroves; intertidal mud banks control; new avenues for forestry and social forestry activities; biomass increase along the estuaries to influenced biological productivity; and improve bird and animal life (Untawale, 1996). Goa Government has banned felling of 15 species of mangroves according to the Goa, Daman and Diu Preservation of Trees under Act, 1984. Government of India declared these areas as ecologically sensitive areas under the Environment (Protection) Act, 1986 putting a ban on their exploitation and by the CRZ Notification 1991 prohibited development activities and disposal of wastes in these areas. Ministry had made a plan-scheme for conservation and management of mangroves and coral reefs in 1986 and constituted National Committee to advise the Government on relevant policies and programs. Due to their recommendations 15 mangrove areas in the country were identified for intensive conservation (Anon, 1997; Jagtap et al., 2002).

Main factor for consideration to develop a management strategy for mangroves is to create buffer zones limiting anthropogenic activities around the demarcated corridor of the wetland which could revive its natural functioning (Castelle et al., 1994). It is important to identify the functional values, magnitude and source of disturbance, adjacent land use and to project the possible impact of such stress in long term, etc. Buffer zone might be consisting of diverse vegetation along the

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perimeter of water body, preferably an indigenous one serving as trap for sediments, nutrients, metals and other pollutants, reducing human impacts by limiting easy access and acting as a barrier to invasion of weeds and other stress inducing activities (Stockdale, 1991). In fact, until about 1960s, mangroves of Gujarat were considered as 'economically unproductive areas' and hence, they had faced destruction caused by expansion of economic as well industrial development activities (Hirway and Goswami, 2007).

However, after many years of wide spread destruction and degradation, significant efforts have been made in recent years by the State Government and the International agencies to restore and regenerate the mangrove stock in Gujarat. According to FSI report there was a constant increase in the mangrove cover in Gujarat state since 1987-1999 but in 2001 it decreased from 1031 sq km to 911 sq km. But ever since 2001 the state saw an increase of 135 sq km. There is also a report that Gujarat showed an increase in mangrove cover mainly because of the plantation and protection measures taken by the state in recent years.

Gujarat has decided to undertake a major drive of mangrove plantation along the coastal regions of Kutch and Jamnagar under Gujarat Forestry Development Project. The state forest department has commissioned about Rs. 830 crore projects for restoration and development of mangrove plantations. Accordingly, the project aims to conserve existing forest cover and also provide viable livelihood options to the tribal. The project has been envisaged for an eight-year period, starting from 2007-08 to 2014-15. The project activities is confined to the forest areas of eastern tribal belt of the state, reserved grasslands in , mangroves in Kori Creek, Kutch Coast, Marine National Park in Jamnagar Division.

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Mangrove Conservation and Restoration

It is estimated that the total area of Mangroves in India is 6740 sq. km. and having about 59 species and 41 genera belonging to different families. Mangroves are distributed in nine state of India in which Sunder bans of West Bengal (4200 sq.km.) and the Andaman and Nicobar Islands (11 sq.km.) cover the major portion of the Mangroves. Large tracts of mangroves are being cleared for agriculture, aquaculture, and industrial use, construction of harbors leading to degradation of mangroves. Further, they are deteriorated in terms of silt in the form of terrestrial and alluvial sediment, crude oil and petroleum derivatives sewage pesticide industrial wastes. Hence, there is a need for specific to preserve and conserve mangroves. Conservation of mangrove is an important commitment for all the countries that possess mangrove ecosystem. Awareness spreading globally on the value of such ecosystem is increasing. Hence, governments of these countries need to conserve by legislating new laws.

Mangrove habitats are decreasing around the world at an alarming rate mainly as a result of the increase population in coastal areas. Conservation of these habitats meant for the maintaining of their rich biodiversity, sustainability of fishery, forestry and other products, and protection of coastal areas from burning effects of natural calamity (Kathiresan and Qasim, 2005). Some important measures should be taken to conserve such fragile ecosystem. MoES has encouraged individual state to develop their action plant to conserve mangroves. Reforestation and Aforestation activities are already planned by Government of Goa. State forestry division has developed approximately 50 hectares of mangrove plantation per year (Jagpat et al, 2003).

Mangrove regeneration is most important practice to conservation. It can be done by natural and artificial way. In Natural way regeneration process is initiated by mangrove seeds. This practice is cost effective and causes no harm to the habitat.

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Artificial regeneration is carried out by nursery development and transplanting seedling to the potential areas. The technicality to develop nursery and aforestation of mangrove is initiated by various organizations including national Institute of Oceanography (NIO), different NGOs, Local community, State government etc. They provide information to the various state Forest department and private sector for mangrove restoration. The nursery development and transplantation operation are economically quit feasible. State Forest department of Goa Gujarat and other part of central west coast have been practiced for plantation of mangroves. Mangrove’s conservation and restoration in Gujarat state may be listed amongst the best conservation stories in the worlds. The state has planned to expand the mangrove cover in the potential areas which are half of the present cover of mangrove.

Public Awareness and People Participation

The rapid destruction of mangroves is due to lack of awareness about the value of it. Educational programs are very important to increase public awareness about the ecological and economical importance of mangrove ecosystem. Participation of local user communities plays an important role in conservation and management of the mangrove resources. It allows people to take responsibility and make decisions in the present and future state of mangrove ecosystem. Government, the community of local resource users, nongovernmental organizations (NGOs), academic research institutions and other stakeholders (fish traders, money lender, tourism promoters) should share their responsibility and authority in decision making of the sustainable management of natural resources. This system is called as ‘Joint natural resource management (Pomeroy and Katon, 2002).

These management options enable people and other organizations understanding the resource crisis and management problems. Australia’s

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mangroves are a valuable educational resource and they are the focus of much study and constant wonder. Aspects of mangrove ecology are an important part of the curriculum of many schools and a number of universities. The Marine Education Society of Australasia (MESA http://www.mesa.edu.au) hosts a website and has been active, for example, in the marine protected areas debate to promote the importance of these areas for education.

Mangrove Conservation and Management

Mangrove conservation and restoration is essential step for all the coastal countries. At national level Framework policy and legislation established and integrated into a broader spatial framework of coastal zone management, should cross all sectors and involve all stakeholders to prevent piecemeal loss and degradation (Lavieren et al., 2012). For example, countries such as Tanzania and Malaysia have placed all mangroves in forest reserves under state ownership. In some locations in Australia and the United States, local policies of “no net loss” have placed specific limitations on future mangrove clearance. These strategies will be effective in the long term if backed by strong political will, enforcement measures and penalties for noncompliance. In the last decade, a study in Thailand replanting costs amounted to US$ 946 per hectare compared to only US$ 189 per hectare for protecting existing mangroves (Ramsar Secretariat, 2001).

An array of market-oriented strategies has been proposed to curtail the conversion of mangrove areas to other land uses. The fact that mangrove forests are increasingly recognized as a valuable source of revenue should in theory make it easier to entice those who benefit from mangroves to make payments for the ecosystem services that they generate (Lavieren et al., 2012). Furthermore, because mangrove forests store significant amounts of carbon and are threatened by the economic attraction of conversion, they could be ideal targets for carbon financing. Such initiatives and investment funds provide exciting new

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opportunities to better protect natural capital, benefit communities, and utilize cost-effective green technologies to address the challenges of climate change.

Coasts are often highly scenic and contain abundant natural resources. People have always been fascinated by the coast. The majority of the world's population lives close to sea. As many as 3 billion people (50% of the global total) live within 60 km of the shoreline. The coast plays an important role in global transportation and is the destination of many of the world's tourist (Woodroffe, 2002).

Coastal zone means the coastal waters (including the land therein and there under) and the adjacent shore lands (including the waters therein and there under), strongly influenced by each and in proximity to the shorelines of the several coastal states, and includes islands, transitional and intertidal areas, salt marshes, wetlands and beaches. It is the interface where the land meets the ocean, encompassing shoreline environments as well as adjacent coastal waters. Its components can include river deltas, coastal plains, wetlands, beaches and dunes, reefs, mangrove forests, lagoons, other coastal features. It’s a dynamic system, affected on a daily basis by marine and sedimentary processes and the related effects of changing weather systems.

Many species are adapted to these unstable habitats, having evolved strategies to either adapt or take advantage of changing substrates. Typically, such areas include a mosaic of habitats from bare sediment to stabilized and vegetated. One of the exceptional ecosystems which occupy this fringe habitat is the coastal ecosystem. It forms one of the most unique ecosystems as it is influenced by both terrestrial factors as well as marine factors. The highly productive coastal ecosystems of the tropics play a crucial role in the economic and social development of the region (Nayak and Bahuguna, 2001). The major vegetation types in this zone include sea grass, macro and micro algae, vegetation on sand patches, salt marshes and the highly productive mangroves.

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Mangrove study is very difficult because thriving at an interface of land and water, which is to say in a complex habitat. This is due to the fact that they occupy the muddy habitats of the coastal ecosystem and to that, their physical adaptations, i.e., their roots, grow in such a way that it becomes near impossible to traverse through a dense patch of mangrove. Studies employing remote sensing have proved to be very useful in such locations (Nayak, 2002, Nayak and Bahuguna, 2001, Green et al., 2000). Satellite remote sensing is an efficient tool that has been adopted increasingly for the detection, description, and quantification and monitoring of the Earth’s natural resources without getting into direct contact. Habitat maps derived using remote sensing techniques are widely and increasingly being used to assess the status of coastal natural resources and as a basis for coastal planning and for the conservation, management, monitoring and valuation of these resources (Green et al., 2000). It provides timely and cost-effective data over inaccessible areas, complementing field surveys, which are of higher information content but are more difficult to carry out, especially in the case of mangroves. In this context, a combination of remote sensing and ground-truth measurements, analyzed within a geographic information systems (GIS) platform, is found to be highly advantageous (Behra et al., 2011).

Despite their well-known limitations in coastal waters, the ocean color sensors provide a unique means for observing the phytoplankton distribution over the continental shelf. However, optical techniques from space platforms are hampered by clouds and cannot be used alone for the monitoring of the phytoplankton throughout the year. For that purpose, they need to be associated to biogeochemical models to be fully efficient. Satellite maps, calibrated on field measurements, can be used to validate and constrain the physical and biological parameters of the models or provide data for assimilation. In coastal waters, light is very often a key limiting factor for the phytoplankton growth and the light

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attenuation coefficient in the euphotic layer is a major parameter in ecological modeling. The chlorophyll, as an indicator of the biological particles, and the inorganic suspended Particulate Matter (SPM) govern a large part of the absorption and scattering properties of the coastal waters. Both quantities are simulated in the coastal ecological models and can also be retrieved from ocean color data.

3) Prioritization

 State of the art development of “Centre for Climate Study” (CCS) for Complete status documentation and conservation, development and management of shoreline diversity of entire Gujarat coast.

 Networking of Universities, Research Establishments, NGOs and Government for effective coordination

 Industrial linkage for establishment of profitable enterprise and livelihood of local community in each region.

 The centre is also planned to have facility of Germplasm conservation of shoreline diversity.

According to 1991 Census, about 549 villages with the total population of about one million are situated along the Gujarat coast. The longest coastline dotted with 41 ports caters to demand & supply of cargo from the nearest maritime countries like Africa, Middle East & Europe. Besides this, the entire northern India and some parts of the central India also serve as hinterland to the ports. Out of a total 142 minor and intermediate size ports, 11 and 29 are situated, respectively, on Gujarat coasts. Of the total 27,175 sq. km of wetland area in Gujarat, the coastal wetlands constitute 92.3%. Gujarat coastal wetlands have marine biodiversity of global to national to local significance. Importantly, these bio-diverse system act as barrier against natural calamities like storms, cyclones,

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strong winds etc. To protect these systems, one marine national park and four sanctuaries are also created along the coastline of Gujarat.

Gujarat is covered between 20° 6’ N to 24 ° 42’N and 68° 10’ E latitude to 74° 28’ E longitude. The state shares its international boundary with the country of Pakistan on the North West side. It is bounded by the Arabian Sea in the west, by the state of Rajasthan in the north – north east, by Madhya Pradesh in the east and by Maharashtra in the south – south east and the Union territories of Diu, Daman, Dadra and Nagar Haveli in the south. The state also has the longest coastline in the country measuring about 1,600 km along western parts of India, extending from Lakhpat in north to Valsad in South. The climate of Gujarat is moderate with mean temperature 25°C to 27.5°C, with annual rainfall between 800-1000mm. The state has an area of 1, 96,022 sq.km and divided into 26 districts.

The Gujarat State is the predominantly an arid and semi arid region. But, due to its geographical condition and topographical variation it is very rich in its ecological wealth ranging from grassland, forest, wetlands, saline deserts and coastal systems. Gujarat represent a unique terrene consisting of naked tidal mudflats transected by various dead and live creeks, also having various marshes with aquatic plants and varying types of lakes are characteristic feather of this region. However, most of these ecological systems are facing threats of different kinds originated from almost all the above defined pressure of anthropogenic nature. Considering width and length of the state, and spatiotemporal variability of different resources, development of computerized information system is the most appropriate answer for coast effective planning and management of various natural resources of the state.

Gujarat is only state of the country having two gulfs viz Gulf of Kuchchh and Gulf of Khambhat which provides opportunities of trade through sea. State coast

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is distinct from the other coasts with shallow depth, wider continental shelf and vast stretches of saline and tidal mudflat. The longest coastline is approximately 21% of the entire Indian coastline. It has been broadly divided into four geomorphologic and oceanographically distinct sub regions. . The entire Gujarat coast has been broadly divided into five distinct but interconnected regions. These include, (i) Gulf of Kachchh, (ii) Gulf of Cambay, (iii) Saurashtra Coast (iv) South Gujarat Coast and (v) Rann of Kachchh. Gulf of Kachchh (GoK) is very rich in terms of biodiversity values. The GoK support varied habitats including coral reefs, mangroves, creeks, mud flats, islands, rocky shore, sandy shore etc., which in turn provide suitable environment for wide range of flora and fauna. Of these habitats, coral reef systems are quite unique in terms of its isolation and surviving in extreme oceanographic and climatic conditions.

Surface trace gases shows an increasing tendency over the western Indian region (Naja and Lal., 1996) due to large scale local/regional emission of O3 precursors. This region directly experiences outflow of upwind continents (Africa/Europe) due to prevailing westerlies resulting in tremendous increase in various trace gases and aerosol concentrations in the lower troposphere (Srivastava et al., 2011). In addition to Indian regional emission; anthropogenic emission over the southern Europe, natural emission over the Arab countries and biomass burning over the middle Africa may be contributing towards these enhancement over the western Indian region. Dispersion and transport of anthropogenic pollutants emitted over polluted cities of western India influence cleaner downwind continental locations (Chand and Lal, 2004) and the Arabian Sea (Lal and Lawrence, 2006). Spatial extent of these transported species, their interactions with aerosols, degree of pollution, O3 photochemistry and their impacts over the downwind locations are not well understood due to very limited in-situ measurements (high cost, poor spatial coverage) over this region. The trace gases concentration over the rural site “Vallabh Vidyanagar” is comparable and

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sometimes higher during winter season as compared to an urban semi-arid site “Ähmedabad” in western India. These differences may be due to various localised anthropogenic sources and the role of meteorology at the receptor location.

4) Quality of Institute (NAAC grade) and Faculty undertaking Research: 1) NAAC Grade:

Gujarat University, Ahmedabad B (2.85 CGPA) Networking Universities Saurashtra University, Rajkot A

S. P. University, Vallabh Vidyanagar B

M. K. Bhavnagar University -

M. S. University of Baroda, Vadodara B

Hemchandracharya North Gujarat University, Patan

Faculties from Nodal University Gujarat University, Ahmedabad Dr. Archana U. Mankad, Prof. & Head, Department of Botany Dr. H. A. Pandya, Professor, Department of Botany Dr. H. A. Solanki, Professor, Department of Botany Dr. Meenu Saraf, Prof. & Head, Department of Microbiology Dr. M. E. James, Professor, Department of Physics Dr. K. H. Chikhalia, Prof. & Head, Department of Chemistry Dr. N. K. Jain, Professor and Head, Department of Life Sciences Dr. H. A. Modi, Professor, Department of Life Sciences and other faculty members would be involved/consulted/invited as and when the subjective requirements arises to meet the proposed objectives.

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Faculties from Networking Universities: Saurashtra University, Rajkot Dr. S. P. Singh: Prof. & Head, Department of Biosciences Dr. Rahul Kundu, Professor, Department of Biosciences Dr. Ramesh Kothari, Professor, Department of Biosciences Dr. H. H Joshi, Prof. & Head, Department of Physics and other faculty members would be involved/consulted/invited as and when the subjective requirements arises to meet the proposed objectives. M. S. University of Baroda, Vadodara Dr. Sarita Gupta, Professor, Department of Biochemistry Dr. Dinesh Kanchan, Professor, Department of Physics Dr. Arun Arya, Department of Environmental Science Dr. Chamiyal, Professor, Department of Geology and other faculty members would be involved/consulted/invited as and when the subjective requirements arises to meet the proposed objectives. Maharaja Krishnakumar Sinhji University, Bhavnagar Dr. Bharti P. Dave, Prof. & Head, Department of Biosciences Dr. Indra Gadhvi, Asso. Prof. & Head, Department of Marine Science and other faculty members would be involved/consulted/invited as and when the subjective requirements arises to meet the proposed objectives. S.P. University, Vallabhvidyanagar Dr. N. V. Shashtry, Professor, Department of Chemistry Dr. T. V. Rammana Rao, Professor, Department of Bioscience Dr. A. S. Reddy, Professor, Department of Bioscience Dr. K. C. Patel, Professor, Department of Microbiology Dr. N. K. Bhatt, Associate Professor, Department of Physics and other faculty members would be involved/consulted/invited as and when the subjective requirements arises to meet the proposed objectives.

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Hemchandracharya North Gujarat University, Patan Dr. Shreyas Bhatt, Professor and Head, Department of Biosciences Dr. Ila Patel, Associate Professor, Department of Biosciences Dr. Nishith Dharaiya, Associate Professor, Department of Biosciences and other faculty members would be involved/consulted/invited as and when the subjective requirements arises to meet the proposed objectives.

5) Accountability of the Project (University/State): Universities: Gujarat University would be the Nodal University Faculty and department involved from each university in the project would be responsible for appointment of necessary hiring, purchase, research, analysis, documentation and completion of the project as per the proposed objectives. State: Knowledge Consortium of Gujarat (KCG), Ahmedabad would be coordinating agency between RUSA and participatory universities for progress, completion and recommendation of necessary project outcomes for future policy frame work based on the research outcome. Development of network is expected between the universities, NGOs and Government (state & central) to address issues regarding the shore line diversity and ecosystem management.

6) Phases/ implementation milestones and plan of action for 2016-2021 2016-2020:  Field survey of Gujarat shore for scouting, documentation of flora and fauna including microbial diversity. Analysis of the physical, chemical and biological parameters and oceanographic studies with respect to the Climate Change impacts.

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Critical th 5 Year analysis, compilation,

documentati Field survey, 3rd Year & 4th Year on and sample, submission collection, of Report. Field survey, analysis & RS

nd sample, studies, 2 Year Recommend collection, Scouting, record ations of analysis & and Desktop study, Action plans RS studies, documentation, primary & for policy Scouting, preservation Secondary data making and record and techniques of st collection from implementat 1 Year documentati collection and literature ion on, data validation regarding define study area with preservatio Development of satellite images n techniques region specific etc, of collection model for flora development of and data & fauna project validation blueprint

2020-2021:  Analysis, evaluation and documentation of data collected through field survey and remote sensing  Introduction of region specific model for development and conservation of shoreline diversity  Recommendations of Action plans for policy making and implementation

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 Basic infrastructure, laboratory equipments and other necessary support like computational facility, library for literature survey, software for analysis and other facilities would be provided by coordinating universities.

 Other heads like Major Equipments purchase, Manpower, consultancy, travel, promotional activities, academic collaborative events, awareness programme etc would be taken care from the funds received from RUSA

 Establishment of “Centre for Climate Studies” at Gujarat University, Ahmedabad is expected from this project

7) Financial resources, financial plan and financial sustainability: 2016-2021 Manpower (Tentative): (A) Soft Component Sr. No. Content Gujarat Saurashtra MKB M.S. S.P. Hemchandra Budget University, University, University, University of University, charya In Lacs Ahmedabad Rajkot Bhavnagar Baroda, Vallabh North Vadodara Vidyanagar Gujarat University, Patan 1 Research Associates (22) 09 09 01 01 01 01 686.40 at Rs. 40,000 + HRA + applicable allowances/ (approximately Rs. 52,000/PM) 2 Junior Research Fellows 15 15 03 03 03 03 756.00 (42) Rs. 30,000/- PM Fixed 3 Technical Assistants (20) 06 06 02 02 02 02 180.00 (Computer + Laboratory) Rs. 15,000/- PM. Fixed 4 Field Assistants (24) 06 06 03 03 03 03 144.00 Rs. 10,000/- PM Fixed Total: (A) 1766.40

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Technical/laboratory/field requirements: (B) Content For 60 months Contingency including 162.0 books, e-resources, promotional academic events, collaboration, etc: Glass ware, consumables 135.0 etc: Chemicals, materials, 560.0 specimens, storage devices, containers etc: Travel including ship time 150.0 (Surface and High Sea) as well as visiting experts, investigators, students, research scholars, etc: Hiring services including 105.0 out sourcing of data analysis, consultancy etc: Miscellaneous (Stationary, 090.0 computers, furniture, fixtures, peripherals, software, etc) Total 1202.0 Institutional Overheads 0180.30 15% Grand Total 1382.30

Total (B) Rs. 1382.3 lacs (Rupees one thousand thirty three hundred thirty seven only) Equipments as Hard component: (C) Rs. 900 lacs (Annexure-I) Minor equipments are available with the individual universities. As the research investigation would involve exhaustive laboratory as well as field experiments, there would be special/specific requirement for high end equipment for analysis, evaluation, authentication and record of reliable data. Necessary equipments would be purchased

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or the services be hired accordingly. The satellite data purchase/procurement could be more expensive. The provision for the same would be extra as actual incurred for the entire project period.

Total Budget Requirement: Component (Hard & Soft) Rupees in Lac Part-A 1766.40 Part-B 1382.30 Part-C 0900.00 Grand Total 4048.70

8) Quality improvement/gap filling projection Gujarat University is coordinating one of its kind course on Climate Change Impacts management since 2008. We are offering M. Sc./ M.Phil./Ph.D. programme for the same. We have established “Centre for Climate Studies” (CCS).

Government of Gujarat, Gandhinagar has facilitated the centre with the grant of 138 lakhs for the same.

 “Centre for Climate Studies” would coordinate as centre for excellence in Climate Change Impacts Management research for Western India

 Networking universities are expected to produce more than 20 Ph.D.s and 30 M.Phil.s out of this investigation.

 More than 40 faculties and 100 research personnel from 06 universities would coordinate for this project

 We are expecting more than 40 research articles of high merit from this extraordinary research plan

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 A record of many new species would be generated

 Fresh understanding of biological, physical and chemical importance would be established

 Novel region specific models would be developed for sustainable practices

The documented data would be exhaustive (a complete package) and useful for the academics, researchers, newly developed industries, different NGOs, various government departments, policy makers, For the Environment Impact Assessment study, already established industries (Small and large scale both), Urban planners, Environmentalist as well as economists. In short it would be the comprehensive inventory of all the scattered information and database as well.

In present study, coastline change needs to be mapped an analysed under two categories, Erosion and deposition. Remote Sensing can be chosen as a tool for enquiry due to the availability of archival data and the ability to track entire shoreline instead of field based measurements at fixed intervals. The synoptic and temporal coverage can be a key benefit of using satellite imagery.

Ironically, all these coastal regions are facing inherent challenges of economic development and associated environmental degradation. They are vulnerable to various developmental activities including rapid industrialization and coastal infrastructure expansion projects as a part on economic development of the state. These seriously alter the land use system of the region.

The research in coastal and shoreline area in state of Gujarat is exhaustive but unorganized. There is no correlation or evaluation done so far for the complete coastal area and its diversity. Therefore, the investigations are available without any scientific justification or relevance.

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Moreover, the understanding of climatic variability is never considered as an important phenomenon. Comparative and evaluative studies with reference to climate change and its impacts on various ecosystem components would be promising to maintain, conserve and develop the available diversity along the shores of Gujarat.

9) Evidence/ plan of academic-industry partnership Gujarat University has signed MOUs with National innovation Foundation (NIF), Confederation of Indian Industries (CII), GEER foundation, CEE, several NGOs and research establishments of National and International repute. 1. Comprehensive data generated out of this research and investigation would be shared with NIF and CII for necessary development of sustainable model for commercial purpose. 2. Industry-Academia interaction/collaboration would be established right from the first year for incorporation of ideas and subsequent IPR, trademark, patent etc. 3. Implementation of Sustainable long lasting applicable model with overall supervision of University Networking System (UNS) and Government

10) Promotion of innovation  IPR Cell sponsored by Gujarat Council on Science and Technology (GUJCOST) a Government of Gujarat enterprise is established at Gujarat University.  In addition to that, the novel developed models would be used to predict the future trend for the regional ecosystem and human activities related to tourism, use and exploitation of the bioresources.  Industrialization of Ethnomedicinal, medicinal, livelihood components will be practiced with the help of National Innovation Foundation (NIF) and Confederation of Indian Industries (CII).

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11) Manpower augmentation/ recruitment or engagement of highly qualified researcher- whenever applicable

I). Research Associates (only Ph.D.) (22) II). Project Fellows (Master Degree) (42) III). Project Assistants (Science Graduate) (20) (06 Computer + 14 Laboratory) IV). Field Assistants (24)

Expected M.Phil. : 30.,

Expected Ph.D.: 15

Expected Post Doctoral Fellows- 09

Research Publications: more than 30

Annual Reports-05

Project Report with ISBN

Total 126 Research Personnel would be coordinated by more than 40

faculty members from 06 net working universities of Gujarat state.

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Part-B

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1). Existing body of research work in Gujarat: In last two decades, the state of Gujarat has progressed vibrantly. The Government of Gujarat has introduced many SEZs, industrial, commercial as well as residential set ups along the sea shore. These developmental processes are expected to grow three to five times in coming ten years. Therefore, the pressure on the shoreline diversity would be severe. The shoreline and coastline research is coordinated by following participatory universities in collaboration with SAC/ISRO, GOG, MoES, UGC, etc in the state of Gujarat. The research projects are in various fields of biodiversity, coastal environment, oceanography and atmospheric science. It is the need of the time that these research capabilities coordinate for larger interest of the state, Gujarat having more than 1600 Km coastal area with rich diversity of flora and fauna.

The expected research coordination of these major universities are as follows; Nodal University: Gujarat University, Ahmedabad Net Working Universities: Saurashtra University, Rajkot S. P University, Vallabh Vidyanagar Maharaj Krishna Kumar Sinhji University, Bhavnagar M. S. University of Baroda, Vadodara Hemchandrachrya North Gujarat University, Patan

In addition to these, Conservation and protection of the coastal resources – (i) mangrove plantation by Gujarat Ecology Commission, (ii) coral reef regeneration by the Forest and Environment Department and GEER Foundation, (iii) mangrove and shelterbelt plantation by the Marine National Park, and (iv) a marine aquarium at Dwarka, by the Forest and Environment Department, Govt. of Gujarat through a private-public partnership model is also considered for collaboration and coordination of research outputs. These agencies are also working on such designated areas. The establishment

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of network between all these research oriented capacities is essential. The attempts are also planned to include local community and villages. Environment and pollution management – (i) completing the environmental sanitation of Jamnagar city, by the Jamnagar Municipal Corporation (ii) capacity building of the Gujarat Pollution Control Board.

Livelihood security of the coastal communities – (i) livelihood improvement activities by the Gujarat Ecology Commission in the non-forest villages of the coast, and (ii) ecotourism and related livelihood improvement activities by the Marine National Park for villages within the protected areas.

1) Rationale/Significance/expected contribution of the project India has a vast extent of coast line of about 8000 km spanning 13 maritime mainland states and Union Territories, which are home to a diversity of coastal and marine ecosystems, comprising nationally and globally significant biodiversity (Venkataraman and Wafar, 2005). The total number of recorded marine species (both plants and animals) is less than that of terrestrial habitats. It is because of the fact that marine diversity has not been fully understood due to logistic constraints in explorations and collection of specimen. Coastal zone represents 18% of the Earth surface providing space to about 60% of the human population. It is important bio-geochemically as it buries and mineralizes 89 to 90% of organic matter and acts as a sink for an estimated 50% of the global carbonate deposition. It also supports almost 30% of its human population being dependent on the rich exploitable coastal and marine resources. Marine ecosystems such as estuaries, coral reefs, marshes, lagoon, sandy and rocky beaches, mangrove forests and sea grass beds are all known for their high biological productivity, which provide a wide range of habitat for many aquatic flora and fauna. It also provides important food resources and critically major services to human beings.

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Therefore, sustainability of these fragile ecosystems should be our primary concern. So far, we have largely looked the marine biodiversity as a source of commercial products instead of appreciating their ecological values and services which has resulted in over exploitation and several species are now in the verge of extinction. Moreover, human activities such as destructive fishing, shipping, coastal developments, discharge of untreated effluent from industries have caused considerable damage and pose a severe threat to the coastal and marine biodiversity. In addition to that, global warming due to climate change also poses major challenges to marine biodiversity. The sea around India is part of the great Indian Ocean and the Indian subcontinent forms a major physical division between the Arabian Sea and the Bay of Bengal of the Indian Ocean. Coral reefs are diverse and most vulnerable ecosystem in India. The reef bio-composition is quite significant and includes 180 species of benthic algae, 14 species of seaweeds, 12 species of seagrasses, 108 species of sponges, 4 species of lobsters, 103 species of echinoderms, 600 species of fin fishes and also a good number of species of crabs, bivalves, gastropods and cephalopods each in Lakshadweep and Andaman and Nicobar islands (Devaraj, 1997). In India, 208 species of hard corals belonging to 60 genera have been so far described (Venkataraman et al., 2003). Highest diversity of corals has been recorded in Andaman and Nicobar islands. India is one among 17 mega biodiversity countries in the world and also ranked 14th among the 22 countries which contain the world's major mangrove areas.

The Sundarbans make up the single largest contiguous block of mangrove forest in the world, with 40 percent of the area within in India and rest is in Bangladesh. As is the case elsewhere, the mangroves of the region have great economic value and have been heavily exploited. Both in western and southern India, and throughout the Bay of Bengal, much of the originally extensive mangrove stands have been removed due to urbanization. Large sea grass beds are present in southern India in Palk Bay and the Gulf of Mannar. However, along much of the coast of western India dense sea grass beds are uncommon or not extensive, probably because of the degree of exposure and

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turbidity of these waters. There are some sea grass beds in the Locatives and they are possibly extensive around the Andamans and Nicobars. It is estimated that perhaps five percent of the sea grass beds of the Indian Ocean had been destroyed by dredging or infilling. About 844 species of marine algae are recorded from India.

Of these, several species are exploited commercially on a large scale in the region. Marine invertebrate diversity is also high in India, and for some groups may show a similar trend to that for corals described above, however, there is not enough study in this group in India. Many invertebrates are harvested and are of economic importance; there is evidence that some molluscs and crustaceans have been overexploited, and species such as the coconut crab, horseshoe crabs, and certain molluscs are of conservation concern. Prochordates in India is a very poorly studied group. Balanoglossus Ptychoderaflava is a wormlike animal with a localized distribution and the Krusadai Islands of Tamil Nadu is one among the few places in India where this species occur. Ascidians such as Herdmania and Eceinascidia, and Amphioxus Branchiostomalanceolatus are also occur in India but these protochordates need more studies. Commercial and subsistence fisheries are important in India (Pernetta, 1993). In India the bulk of the catch is subsistence or artisanal. Hilsa is the main species have been exploited in the Bay of Bengal. The Bay of Bengal is particularly rich because of the nutrient input from the large rivers and there is extensive information available for the fisheries of this area through the Bay of Bengal Programme on marine fishery resources. Five of the seven species of sea turtles found worldwide are reported to occur in Indian coastal waters (Kar and Basker, 1982, Bhupathy and Saravanan, 2003). These are the olive ridley (Lepidochelysolivacea), green (Cheloniamydas), hawksbill (Eretmochelysimbricata), leatherback (Dermochelyscoriacea) and loggerhead (Carettacaretta).

Except for the Loggerhead, the remaining four species nest along the Indian coastline. A significant proportion of World’s olive ridley population migrates every winter to the

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Indian coastal waters to nest on beaches in Orissa, as well as along other parts of Indian coast. All the five species of sea turtles that occur in Indian coastal waters are protected under Schedule I of the Wildlife Protection Act (1972), as well as listed in Appendix I of Convention of International Trade in Endangered Species of Wild Fauna and Flora (CITES) which prohibits trade in turtle products by signatory countries. At present there exists no commercial or international trade of marine turtles or turtle products in India. However, incidental capture in trawls is a well-known cause of mortality for sea turtles and have been reported all over the world and India is not exception to this. Globally threatened marine and coastal bird species such as the Spot-billed Pelican Pelecanusphillipensis and the Lesser Adjutant Leptoptilosjavanicus are found in India. Important Birds Areas (IBA) along coasts includes the Gulf of Kutch, Gulf of Mannar, Coringa, Pulicat, Chilka Lake etc. The seabirds of the region are poorly known and do not appear to be abundant in off-shore India, The Sundarbans are an important staging and wintering area for gulls and terns.

Many of the atoll islands in the Laccadives-Chagos chain may have seabird colonies, such as Pitti and Baliapani in the Laccadives and several of the Chagos Archipelago islands. About 25 species of marine mammals known to occur in Indian water. Apart from larger cetaceans such as baleen, sperm whales etc., there is also a large number of small cetaceans occur in Indian Ocean, some of which are not well known, and many of which are harvested either intentionally or incidentally. The Indian Ocean populations of the humpback dolphin Sousa chinensis and the spotted dolphin Stenellaattenuata are considered to be at risk; the distribution of the latter appears to be closely correlated with mangroves. The distribution of the dugong extends over most of the region, but appreciable numbers are no longer found. The most important area for this species in the region, and possibly in the whole Indian Ocean, is the Gulf of Mannar, Palk Bay and Gulf of Kutch in India, and Andaman and Nicobar islands. The Coastal Regulation Zone Notification, 1991, National Biodiversity Act, 2002 and the Environment (Protection) Act, 1986 have been enacted by India for the conservation of coastal and

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marine environment along with the Wildlife (Protection) Act 1972, which also provides for the establishment of wildlife Protected Areas by State Governments. So far, about 25 Marine Protected Areas have been established. The Gulf of Kutch Marine National Park, the Gulf of Mannar National Park and Wandoor Marine National Park are some of the important MPAs of India.

Status of Marine Biodiversity Like its rich terrestrial biodiversity, India is equally rich in marine biodiversity. India's coastline which is more than 7500 km in length including those of islands of Andaman & Nicobar groups and Lakshadweep, harbors unique marine habitats which display a wide variety of marine biological diversity. The coastal waters along the East and West Coast of the country and also around the two island groups have a plethora of marine species. The marine floral diversity includes 844 species of marine algae (sea weeds) belonging to 217 genera, 14 species of sea grasses and 69 species of mangroves.

The marine faunal diversity includes a wide variety of life forum. The Indian coastal water harbors 451 species of sponges, more than 200 species of corals, more than 2900 species of crustacean, 3370 species of marine mollusks, more than 200 species of bryozoans, 765 species of echinoderm, 47 species of tunicates, more than 1300 marine fishes, 26 species of sea snakes, 5 species of sea turtles and 30 species of marine mammals including dugong, dolphins, whales etc. In addition a wide variety of sea birds can be observed around the coast.

Gujarat Diversity The state has two coastal region is spread from high rainfall area (about 2,500 mm in south Gujarat) to low rains area (only 250 mm in the north-west of Kachchh). These are the main reasons for extensive and diverse marine eco-systems in India. Temperature, salinity and depth are the chief barriers against free movement of marine organisms. Many kinds of waves, tides, cyclone and currents etc. in the sea influence the physical

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and biological conditions of the marine ecosystems. Richness increases with productivity, geological and climatic stability and decreasing latitude. Diversity of flora and fauna is high in the wetlands of Gujarat. A total of 323 species of wetlands of India are endemic or globally threatened, and at least 30 of them are from Gujarat. Of 114 endemic wetland plants of India, 11 are found in the wetlands of Gujarat.

There had been great changes in the environment of this region due to change in climate, gradual rise of mudflats, restricted flow of rivers as a result of construction of dams and destruction of original setting of mangroves. With increased protection during the recent past, Avicennia sp. has started colonizing suitable mudflats. In this process, the succession has started in majority of sites, including on islands (Bets) in the Notified mangrove areas as forest in Gujarat (Area in sq. km) District Area Jamnagar 665.93 Rajkot 77.70 Sub-total for Saurashtra 743.63 Kutch 581.80 Grand total 1324.43 District-wise mangrove cover (FSI 2009)5 District Area in sq. km. Some of the mudflats, which supported mangroves in the past, are no longer suitable for growth of vegetation as areas changed into hyper-saline lands. But on the other side, some seaward mudflats provide ideal conditions for regeneration- a process of primary succession. Unlike high rainfall area in the tropical region, mangroves in Gujarat are shrubby and they are distributed in discontinuous patches with blanks and marsh vegetation within them. But the patches of mangroves in south Gujarat are luxuriant and diverse.

The dominant mangrove vegetation along Jakhau, Koteshwar and Lakhpat is mainly of Avicennia marina var. acutissima, which forms almost a pure stand. Earlier reports indicate that Avicennia officnalis, Rhizophoramucronata, Bruguieragymnorhiza and Ceriopstagal were found associated with Avicennia marina. Presently these species have become rare or absent. Huge formations of Sesuviumportula,castrumoccur on the marshy fringes of mangroves associated with Salicornia brachiata, Suaedafruticosa, Cressacretica and Aeluropslagopoides. In the low lying areas Juncusmaritimus occur in pure patches. In the areas with low salinity grass species such as Dichanthiumannulatum, Sehimanervosum,

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Cenchurussiliaris, C. setigerus and Panicumantidotale occur along with Acacia nilotica and Capparis sp. The Climatic factors such as temperature fluctuation, humidity, precipitation, number of rainy days, air, moisture, radiation and fresh water flow in the region, act as the most significant factors for natural growth, development and succession of mangroves. These factors also govern the salinity of the mudflats, which support tidal vegetation. Distribution of mangroves is mainly restricted to the tropical region, but some species have adapted to grow in subtropical and semi-arid region.

Sea Grasses and Sea Weeds Sea grasses are monocotyledonous plants found submerged in shallow and sheltered localities of sea, gulf, bays, backwaters and lagoons. They play an important role in the conservation of many endangered species like dugong, marine turtles etc. About 14 species are reported along the Indian coast. Seaweeds on the other hand are found mostly on flat and rocky coastal wetlands which are submerged during high tides and subsequently get exposed during low tides. They are found in abundance on the West Coast, Andaman & Nicobar Islands and Lakshadweep, but less frequently along the East Coast. About 120 species of seaweeds have been recorded in the coastal region of India. Seaweeds are known to remove or consume the nutrients like nitrogen and phosphorus from domestic sewage and other effluents, thus, reducing eutrophication. They contain bioactive substances and are important sources of fertilizers and many other commercially important substances.

The sea algae or sea-weeds are widely distributed along the west coast of India and are mostly found attached to substratum of coral or rock. The Gujarat Gulf contributes to the maximum species and biomass of seaweeds for the west coast of India. Between the two coasts of GoK- the northern and the southern- the later supports luxuriant growth of marine algae because shoreline has gradual slope with high tidal amplitude, moderate wave action and low turbidity. Also, presence of hard substratum both due to

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coral reefs and other rocks, provide suitable habitat for most of the algal species. The northern shore of the Gulf has very poor algal growth, as the sandy/ muddy substratum associated with relatively high turbidity does not support the species Inter- tidal area at Narara. Sea grasses are flowering plants of the seas. In tropical region, sea grass beds occur in association with coral reefs as well as in their absence. However, in the Gulf they are highly localized and restricted. Only three species of sea grasses are reported from GoK. Sea grasses are good source of food for marine mammalian and reptilian fauna like Dugong and turtles, respectively.

Oceanographic Characteristics Tides and Currents Tides of the Gujarat coast are of mixed semi-diurnal type. The coast experiences very high tides. The tidal range increases tremendously form the mouth to upstream of the gulfs, due its unique funnel shape. In the Gulf, tidal currents are fairly strong and bimodal in nature having two dominant directions: upstream during flood and downstream during ebb. Due to increasing tidal amplitude, the inter-tidal expanse along the shores of the Gulf increases upstream. It increases from 0.5 to 2 km. from Jakhau to Kandla in the northern part of Gulf and from around 1 km. at Okha to over 5 km. at Jodiya in the southern side of the Gulf. In addition to this, the tidal currents in Gulf are fairly strong and bimodal in nature creating oscillatory motions. Such motions restrict the flushing of Gulf, and thus the residence time is quite long. The low tides leave vast coastal area completely exposed, which get submerged during high tides. The Gulf of Cambay south portion which experiences meso-tidal condition. South Gujarat coastline experiences semi-diurnal tides, with two high and two low tides daily. The tidal amplitude of the meso-tidal range is of the range 6-10 m, increasing upstream.

Sedimentation Sedimentation is a very important physical characteristic of tropical coastal system and controlled by major rivers. Accordingly, the river Indus, located further north of the

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GoK, is the single largest source of sediment for the Arabian Sea and also the Gulf of Kachchh (Hashimi et al., 1978, Nair et al., 1982, Chauhan et al., 2006). The Central Water Commission estimated that, for the year 1984, the river discharges about 0.45 × 1012 kg of sediment annually. Further, based on the 22 years data (1956-1978), Chandramohan et al., 2001 estimated deposition of about 0.3 × 1010 m3 sediment in the GoK, caused a reduction in water depth of about 0.54 m, i.e. 0.025 m per year. The above figure is quite comparable with other sites in Indian coastal areas.

During the recent years, however, it has been reported that the sediment outflow from River Indus has reduced from 400 million tons per year in 19th Century to the recent 40 million tons per year, because of the construction of several dams and reservoirs across the river (Milliman et al., 1984). Interestingly, while the northern and eastern part of the Gulf received most of the sediments, the southern portion of Gulf is devoid of sediments (Kunte et al., 2005) because of the existence of a dynamic barrier caused by the high velocity tidal stream flowing through the central channel of the Gulf (Hashimi et al., 1978, Nair et al., 1982a, Chauhan, 1994). The adjacent landmass of Kachchh and Saurashtra contain rich sediments due to weathering of Deccan Trap material (Patel, 1987) but contribute little to the Gulf due to lack of any major river and also limited run- off.

Furthermore, near shore shallow regions between Okha and Sikka recorded low suspended solids (15-40 mg/l) whereas the inner Gulf areas witnessed markedly higher values, often in excess of 100 mg/l. The spatial distribution of sediment in the GoK, effectively determined the settings of different coastal resources, mainly the coral reefs and mangroves. Devoid of coral reefs in the northern side of the Gulf and better growth towards the central and southern part of Gulf, had clear relationship with the sedimentation dynamics. 2.2.3 Sea water Salinity & Temperature With high tidal range, negligible land run-off and irregular topography, the waters in GoK are vertically homogeneous in terms of salinity and temperature. In the Gulf region, the evaporation

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exceeds precipitation leading to markedly higher salinity than that of the typical seawater. Sea Water Salinity & Temperature With high tidal range, negligible land run-off and irregular topography, the waters in GoK are vertically homogeneous in terms of salinity and temperature. In the Gulf region, the evaporation exceeds precipitation leading to markedly higher salinity than that of the typical seawater. This is particularly evident in the inner part of Gulf where distribution of Sediments in GoK (Kunte et al., 2005; Ramaswamy et al., 2007) salinities as high as 40 ppt. Release of high saline brine waters from adjoining saltpans further enhance the salinity in the inner Gulf. The salinity near the mouth of the Gulf is comparatively lower (around 35 ppt) than that of head region. Therefore, there exist a gradient of salinity in the Gulf. Common wisdom suggests that such difference in salinity in Gulf is reflected in the distribution of Coral reefs as better coral reefs are found towards the western side of the Gulf.

The possibility of increasing ambient temperature due to global climate change could increase the rate of evaporation, and thus the salinity. This could lead to high bleaching or mortality of coral reefs. Hydro-chemically, the Gulf shows properties typical of a shallow semi enclosed sea in an arid region with the little or no freshwater input. The annual variation of water temperature is between 24 and 30°C though localized higher temperatures up to 35°C can result in isolated water pools formed in shallow intertidal depressions during low tide.

Key Habitats & Biological Resources The GoK abounds in marine wealth and is considered as one of the biologically richest marine habitats along the west coast of India. It is endowed with a great diversity of natural habitats and ecosystems. It is important to reiterate here that the Gulf of Kachchh had quite distinct physical characteristics in its northern and southern sides. Thus, one of the most striking features of the southern side of the GoK is the presence of

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many islands and records of coral reefs and mangroves. Realizing the conservation importance of southern part of GoK, in 1980 & 1982 Government of Gujarat had declared most part of this as Marine National Park & Sanctuary (MNPS).

Islands & Islets There are many islands and islets (an islet is a small island) in the Gulf of Kachchh, supporting rich biodiversity. According to official records, there are 42 islands & some islets in the GoK, covering a total area of about 410.6 km2. These islands and islets varied in their size. Also, due to variations in the tidal amplitudes at various locations, the inundation patterns of these islands also varied. While many are partially submerged into the water (known as ‘Areal’ islands), quite a few of these islands are fully submerged even during the normal period. These submerged islands are, however, exposed only during the ‘minus tide’ (e.g. Dona, Boria, Pashu islands etc). As a matter of Light House in Pirotan Island, the inundation pattern of islands is one of the factors determining the presence of coral reefs and /or mangroves. Of the total area of islands, 148.9 km2 have been notified under MNPS. Among all the islands, only two are having human habitations viz. Beyt and Ajad.

Figure:1 Global Distribution of mangroves

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Mangroves Mangroves are an extremely important component of the coastal marine environment, both in an ecological sense as well as in economic terms. Mangrove plants are mostly trees and large shrubs, but also include ferns and a palm species. Thirty-eight of these species might be considered ‘core species’ that typify mangroves and dominate in most locations. The rest are rarely so abundant or are more typically found on the fringes of mangrove habitats. There are two types of Mangroves are found True Mangroves and Mangrove Associates. The plants which are adapted to harsh saline environment are called True Mangroves and Plants that exist in the coastal environment and also found within mangroves are called as Mangrove associates (Wang et al., 2010).

Mangrove plants can survive on high salinity, high temperature, tidal regimes, and strong wind velocity. Mangrove ecosystem is one among the most productive ecosystems on the earth. They serve as custodians of their juvenile stock and form most valuable biomass. They are ecological group of halophytic plants which can thrive on harsh environment so collectively known as mangrove ecosystem rather than plant. This ecological group of plant provides a wide range of ecological and economic products and services, and also supports a variety of other coastal and marine ecosystems (Singh et al., 2012). Mangroves and muddy anaerobic soil. The mangrove ecosystems provide link or bridge between terrestrial and marine ecosystems. They are found in the inter-tidal zones of sheltered shores, estuaries, creeks, backwaters, lagoons, marshes and mud-flats. They are called bio shied of the coastal areas which protect the coast line against natural calamities. Anthropological pressures and natural calamities are the enemies of the ecosystem.

Rapid Industrialization at this area and discharge of domestic and industrial sewage are polluting these areas. Many studies are carried out to highlight these problems and the conservation efforts are being measured to solve these problems. According to World Atlas of mangrove there are total 73 species of mangroves are reported. Mangroves are

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found in 123 countries, covering an area of 152,360 km2. Two-thirds of the world’s mangroves are found in just 12 countries, with Indonesia alone accounting for over 20% of the total mangrove cover of the world (Alongi, 2002 and Giri et al., 2011). Mangroves are possibly evolved just after the first angiosperms, around 114 million years ago (Duke, 1992).

Indian Scenario of Mangroves India, having longest coastline of about 7516 km, mangrove occupy about 5% of global mangrove vegetation and area occupy 4,500 km2; fourth largest area in the world (Naskar and Mandal 1999). The deltaic mangrove occur in the west coast with coastline of about 3000 km, facing Arabian Sea, Insular mangroves are present in Andaman and Nicobar Island and east coast having 2700 km coastline (Gopal and Krishnamurthy, 1993 and Vijaya Kumar and Vijaya Kumara, 2009). Around 70% of mangroves are present at east coast, 12% west coast and 18% of Andaman and Nicobar Island (Kathiresanet al., 1995). The east coast of India has nutrient rich alluvial soil formed by major rivers like Ganga, Brahmaputra, Godvari, Mahanadhi, Krishna and Cauvery as a result huge mangrove covers are found. The total area of Sundarvan mangroves of about 10,000 km2 out of this 60% are in Bangladesh and rest is in India (UNESCO, 1997).

A total 82 mangrove species (52 genera and 36 families) has been reported by different studies. The mangrove area in Orissa is about 200 km2 and its degradation is 20 km2 over ten years. Andhra Pradesh mangrove area is 582 km2, Tamil Nadu has longest coastline of 1076 km2 and major mangrove areas of 225 km2 are in Pichavaram and Muthupet (Singh, 2012).Pichavaram mangrove are largest unspoiled mangrove forest in Tamil Nadu which is dominated by RhizophoraSpp. while Muthupet area occupied 4% by well grown mangroves and holds heterogeneous blend of mangrove plant and animal Gujarat has a diverse mangrove ecosystem ad holds second largest mangrove cover after the West Bengal.

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The Gujarat state’s 90% mangrove cover is spread over Gulf of Kuchchh and rest are at Gulf of Khambhat (Cambay). According to Forest Survey of India mangrove cover in Gujarat state was increasing since 1987-1999 after that in 2001 it start decreasing from 1031 km2 to 911 km2 but ever since 2001 Gujarat mangroves showed increase trend because of plantation and protection measures taken by state (Singh, 2012). Total 15 mangrove species are reported in Gujarat while Maharashtra has 20 species, Goa 14 species, Karnataka 10 Species, Kerala 4 species. Table-3 State wise Mangrove Distributions in India Total (Area in State Very Dense Moderately Dense Open Km2 ) Andhra 0 126 226 352 Pradesh Goa 0 20 2 22 Gujarat 0 175 928 1,103 Karnataka 0 3 0 3 Kerala 0 3 3 6 Maharashtra 0 69 117 186 Odisha 82 88 43 213 Tamil Nadu 0 16 23 39

West Bengal 993 699 405 2,097 A & N 276 258 70 604 Islands Diu & 0 0 1 1 Daman Panducherry 0 0.14 1.49 1.63 Total 1,351 1,457 1,819 4,628

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Gujarat gifted with about 1600 km long coastline which is approximately 21% of the entire Indian coastline. It has been broadly divided into four geomorphologically and oceanographically distinct sub regions. These include Saurashtra coast, South Gujarat Coast and two gulf viz. Gulf of Kuchchh and Gulf of Khambhat (Cambay) covering about 60% of state’s coastline. Importantly, out of three Gulfs in the country, two are situated in the Gujarat coast. More than one million people are directly depending on coastal resources. Gujarat possess second largest mangrove cover in India and shows increasing trend since 1987. Many conservation measures are taken by the state by plantation activities, involvement of local community for conservation and various awareness programs that’s why mangrove area is increased in the state. Total 15 mangrove species are reported from Gujarat out of them Avicennia marina is dominant species.

Ironically, all these coastal regions are facing inherent challenges of economic development and associated environmental degradation. They are vulnerable to various developmental activities including rapid industrialization and coastal infrastructure expansion projects as a part on economic development of the state. These seriously alter the land use system of the region.

The coastal erosion causes are anthropogenic as well as Natural. The Neo tectonic shifts which cause the seabed shift and global warming have caused a sea level rise. But sea destructive work in South Gujarat’s coastal area is due to Continuous mining, construction of dams and illegal sand mining without allowing for ‘sedimentary budgeting’ means a balance should be maintained between the sand removed and the sand added to the beach which resulted in loss of around 20,000 villagers ancestral houses in the region. Now they are called climate refugees which are the reality fact along Gujarat’s 1600 km coast. Strangely, Government is unresponsive to the threat posed by the sea and there is no agreement on what causing these hazards. In the

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coming decade, the sea will come right up to Billimora, which means it will start encroaching on Valsad town very soon.

The coastal area of Gujarat is facing serious coastal erosion. The erosion is taking place mostly under the action of strong tidal current accompanied by wave actions. Mainly, coastal communities are belonging to Machhimar (Fisherman) which is depending on fishing business. Due to heavy damage in fertile of land, coastal vegetation and other properties. Local people often representing for providing protection measures to coastline erosion. In view of above, natural damages, anti sea erosion work are carried out by Government of Gujarat. Coastal districts like Valsad, Navsari and Surat protection measure are taken in terms of Construction of protection wall against sea coast in villages. In this work is carried out in Umarsadi, Kolak-Udwada, Umargam villages, In Navasari district Gandevi and Jalalpore talukas and in surat, Olpad and Choryasi talukas anti sea erosion work and Construction of protection wall against soil coast.

Coral Reefs Coral reef needs specific geo-physicochemical requirements for their growth and development. Thus, they need relatively warm, clear and quiet water for optimal growth. The distribution of coral reefs at any given point in time is determined by various limiting factors. The most significant of these are water temperature, depth and light intensity, movement of water (current), substratum, salinity, water turbulence, and sedimentation. The optimum temperature for the growth of coral reefs is 25-30°C. At temperature below 15°C, the coral growth gets restricted or ceased, while, sea-water temperature above 36°C causes their bleaching. Because of the above environmental requirements, coral reefs are mostly located in tropical waters.

The GoK and Mithapur and Dwarka are the only areas in Gujarat where coral reefs exist. As a matter of fact, at a global level, the coral reefs in GoK are found at the

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northern most limits but for the northern portions of the Red Sea. The reefs are found patchily and, as discussed earlier, located towards the southern side of the Gulf and thus concentrated in . The most northerly patches of coral reefs are found at Mungra reef. The age of coral reefs in GoK vary from 5240 years B.P. at Salaya to approximately 45,000 years B.P. at Okha. Based on the existing classifications most of these reefs are grouped into fringing types. However, solitary and soft corals are also reported near , Mandvi and Kandla in Kachchh (Deshmukh et al., 2000) and in the Arabian Sea along the Saurashtra coast (Raghunathan et al. 2004). According to satellite imagery based assessment, coral reefs in GoK occupies an area of about 460 km2. Creeks &Creeklets There is a network of creeks and alluvial marshy tidal flats in the interior part of the Gulf. The creek system consists of three main creeks namely Nakti, Kandla and Hansthal, and many other big and small creeks. The creek waters varies in the salinity and thus in the associated vegetation. Quite a many creeks are covered by mangroves. The creeks which go quite inwards in the mainland are also responsible in causes for increase in the salinity of adjoining lands.

Drainage Drainage is the reflection of the terrain characteristics and being controlled by physiography, climate and tectonic framework, the rivers in the various physiographic zones behave differently and shows striking diversity (Merh, 1995). The rivers draining the study area fall in to Arabian Sea. These rivers are smaller, compared to the other rivers of Gujarat. They rise within the boundaries of the state from the eastern trappean highlands and finally debouch in to the Arabian Sea.

The regional drainage pattern is dendritic to sub-dendritic in nature. The drainage is usually a function of the topography, which in itself related to the underlying lithology and structural features present in the area. The Banas in the north, originating in the Siranva hill in Sirohi in Rajasthan, flows by the foothills of Abu and disappears in the

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desert. The Saraswati takes its birth at Koteshvar near Ambaji, flows by Siddhpur and Patan and merges into the desert. The Sabarmati, one of the biggest rivers of north Gujarat, originates from the Dhebar Lake in Rajasthan and flows towards the Gulf of Cambay. The Hathmati, Vatrak, Mazam, Meshvo, Shedhi, Khari and the other rivulets also join it. The three virgin rivers of the north and the Sabarmati with its tributaries are the daughters of the Aravalli ranges, while the Mahi and Narmada with their families originate from Madhya Pradesh. The Narmada, one of the biggest and holiest rivers along with the only tributary, Karjan, meets the sea, about 16 kmsfromBaroach. The Tapi takes its birth in the Satpura ranges near Betwa and enters Gujarat at Kakarapar. It flows around Surat and Rander and falls into the sea. The Mindhola, Purna, Ambika, Vanki, Auranga, , Par, Kolak and Damanganga are the rivers of south Gujarat, which originates in the Sahyadri. Most of the rivers of Saurashtra and Kutch dries up in the summer. The rivers which originate in the central Saurashtra in the Chotila range flow to the south into the desert of Kutch. Only the Aji, Machhu and Brahmani are northward flowing rivers. The rivers originating in the Girnar and Gir namely, the Ojhat, Kamb, Surekh, Somal, Sangwada, Hirani, Kapila and Saraswati flow into the sea. The Saraswati and Vastu are sacred rivers. Though Kutch has many rivers, they are small and do not have much water. The Khari flowing by meets the desert and Magh and Tara empty their waters in the Gulf of Cambay. The Rudramata has been banded for irrigation, providing the only irrigation project in Kutch (Kulkarni, 1985, Anonymous, 2014).

Salt Pans Salt pans are human made intervention near the coastline of GoK and create varied habitats for different floral and faunal species. In the GoK, while both northern and southern side are used for salt work purposes, they are mostly located in certain pockets like near Mandvi and Mundra coastline; Surajbari creek at extreme eastern part of GoK; near Jamnagar coast and near Okha at the mouth of the Gulf. While, the total

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number of salt work units in the entire GoK is not available, near the MNPS area there are more than 20 salt units operates.

Tata Salt and Chemical Works at Mithapur near Okha, is one of the largest unit in the GoK. While these salt manufacturing units had many environmental concerns, they also serve as feeding grounds for a variety of resident as well as migrant birds. Poshitra Bay 2021 Gujarat Ecology Commission 2.3.10 Open Water Other than the above described habitats, it is important to mention here that all the above habitats are interconnected with each other by the sea-water and thus energy and material (for example, the nutrients and fish) are exchanged from one system to another. The physico-chemical and oceanographical qualities of sea water are very important and critical for the health of entire GoK.

Atmospheric Minor Constituents: One of the most important minor constituents in the middle atmosphere (heights of10- 100 km) is ozone, because it is the only atmospheric species that effectively absorbs ultraviolet solar radiation from 2000 Ǻ to 3000 Ǻ, protecting plant and animal life from exposure to harmful radiation. Hence a decrease in stratospheric ozone will result in an increase in ultraviolet B radiation, which will have negative impacts on human health. However as ozone is toxic to the living system, elevated tropospheric ozone concentration will damage the tissues of plants and animals and will also cause the temperature of the atmosphere to rise. Thus there is a great need to monitor the atmospheric ozone concentration. Water vapour also plays an important role in the heat balance of the atmosphere and monsoon dynamics. There is an increasing concern about the alarming increase of atmospheric pollution and anthropogenic sources of the depletion of the protective ozone layer. Global change induced by the increasing emission of greenhouse gases is also a matter of scientific concern.

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Aerosols: To estimate and reverse the effect of the human activities on our ‘atmosphere’, it is essential to understand the processes which govern the atmospheric system. The major constituents of the atmosphere, Nitrogen (78%), Oxygen (21%) and Neon (~1%) are controlled over geological time scales by the biosphere, Earth’s crust and the interior. These gases are important for the life to sustain. But the gases which are in trace amount (trace gases) constitute less than 1% of the total atmosphere and the particulate matter, make the earth habitable and thus play a major role in different processes like chemistry, dynamics, transport, etc. Each one of them play a distinct role in the bio- system comprising Sun (radiation), Earth & atmosphere. Troposphere, the lower part of the atmosphere which extends from the ground to about an altitude of 15 km in the tropics is highly influenced by the biogenic activities of the different species on the earth. In addition the atmosphere has tiny solid and/or liquid particles suspended called as atmospheric aerosols (radius ranging from 0.001 to 100 µm). Aerosols have both natural and anthropogenic sources, and the importance of each has significant regional variation and is important components of the earth system. Some of the effects of aerosols are reduction in visibility (Watson, 2002), deterioration of human health (Pope and Dockery, 2006), deposition of pollutants to ecosystems (Bytnerowicz and Fenn, 1996), and direct and indirect effects on the radiative balance of the climate system. Pollution from megacities and large urban areas is important not only for local effects on health, visibility, and ecosystems but also because of their collective influence in regional to global scale atmospheric chemistry and radiative forcing. The aerosols vary considerably in shape, size, concentration and composition because of (i) variations in the strength and nature of local sources, (ii) variations in the mixing characteristics, (iii) variations in the dilution capacity of the air, (iv) scavenging processes and (v) background burden of particles. Aerosols of different sizes, magnitude and composition are produced by the natural or anthropogenic sources and can be transported to different regions depending upon the meteorological conditions. Aerosols have the potential to significantly influence our planet through their role in

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heterogeneous chemistry, as well as their effect on the Earth’s climate as they scatter and absorb visible solar radiation and terrestrial radiation and serve as condensation nuclei for cloud droplet formation (IPCC, 2013). Various anthropogenic sources produces both aerosols and trace gases. Troposphere provides a perfect laboratory to understand the interaction of emissions, in-situ photochemistry, transport, etc of these constituents in our atmosphere. Any perturbation in this system will be reflected on the complete biogenic system due to its inter-dependence. The atmospheric aerosol and trace gases play an important role in the global climate change and in the chemistry of the troposphere. These are highly variable in space and time due to their short lifetime and have significant impact on global climate, the atmospheric environment, and radiative forcing of Earth's climate, but their variable concentrations complicate an understanding of their global influence. Radiative impact of aerosols and trace gases depend not only on their concentration in space and time but also on their magnitude and chemistry.

Motivation for aerosol study

Surface trace gases shows an increasing tendency over the western Indian region (Naja and Lal., 1996) due to large scale local/regional emission of O3 precursors. This region directly experiences outflow of upwind continents (Africa/Europe) due to prevailing westerlies resulting in tremendous increase in various trace gases and aerosol concentrations in the lower troposphere (Srivastava et al., 2011). In addition to Indian regional emission; anthropogenic emission over the southern Europe, natural emission over the Arab countries and biomass burning over the middle Africa may be contributing towards these enhancement over the western Indian region. Dispersion and transport of anthropogenic pollutants emitted over polluted cities of western India influence cleaner downwind continental locations (Chand and Lal, 2004) and the Arabian Sea (Lal and Lawrence, 2006). Spatial extent of these transported species; their interactions with aerosols, degree of pollution, O3 photochemistry and their impacts

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over the downwind locations are not well understood due to very limited in-situ measurements (high cost, poor spatial coverage) over this region. The trace gases concentration over the rural site “Vallabh Vidyanagar” are comparable and sometimes higher during winter season as compared to an urban semi-arid site “Ähmedabad” in western India. These differences may be due to various localized anthropogenic sources and the role of meteorology at the receptor location.

Scientists have much to learn about the way aerosols affect regional and global climate. We have yet to accurately quantify the relative impacts on climate of natural aerosols and those of human origin. Moreover, we do not know in what regions of the planet the amount of atmospheric aerosol is increasing, is diminishing, and is remaining roughly constant. Overall, we do not even know whether aerosols are warming or cooling our planet.

2) Credibility (experience and expertise) of persons involved: Gujarat University, Ahmedabad

i) Dr.Himanshu Pandya, Professor, Department of Botany, Bioinformatics and Climate Change Impacts Management Field of Specialization Medicinal Plants, Marine Biodiversity, Ocean science, Ecology and Climate Change Impacts Management Projects: I) Title: High productivity in the open sea: Quantification of link between physical process and phytoplankton variability Collaboration: Department of Botany and Space Application Center (SAC)-ISRO, Ahmedabad Duration: February,2009 to March, 2013 Total Budget: 15 Lakhs

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II) Title: Chlorophyll pattern in the Indian Ocean, relationship with climate variability & impact on CO2 flux Collaboration: Department of Botany (Dr. Himanshu Pandya) and Space Application Center (SAC)-ISRO, Ahmedabad Duration: September, 2013 to March, 2016 Total Budget: 25 Lakhs III) Title: Facilitation through Hydrological costal habitat modifications in Gulf of Khambhat (Cambay): An exhaustive inventory for native plant diversity and soil dynamics. Collaboration: Department of Botany and Ministry of Earth Science (MoES), New Delhi. Duration:2010 to 2013 Total Budget: 15.98 Lakhs

ii) Dr. Hitesh Solanki, Professor, Department of Botany, Bioinformatics and Climate Change Impacts Management y Field of Specialization Environment Science, Biological Oceanography, Ecology and Climate Change iii) Dr. M. E. James, Professor, Department of Physics, Space Science and Electronics Field of Specialization Ionosphere and geomagnetism, Monsoon meteorology, Aerosol and trace gases, Polar science. Projects:

1. GU-SAC(ISRO) Collaborative Research Project Under MOP-II Program Title: Characterization of Mid-Tropospheric Cyclones (MTC) and offshore trough and its association with Heavy Rainfall events over Gujarat State using INSAT and other collateral data”

Duration of the project: 29th December-2008 - 31st March-2012 Amount utilized : 09 lacs Funding agency : SAC (ISRO)

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II. GU - SAC Collaborative Research Project under PRACRITI Programme

Title: Study of the spatial and temporal variability of trace Gase and Aerosols over Indian Subcontinent using Space Based Measurements Period of project : 27th Oct 2009 to 31st July 2012 Amount Utilized : 06.50 Lacs Funding agency : SAC (ISRO) III. GU-SAC Collaborative Research Project under MOP-III Programme

Title: Polar Environment processes, Global Warming effects and their Indian teleconnection (PENGWIN): Monitoring of the Cryospheric Surface Changes and Ice Thickness Distribution

Period of project : April 2015 – March 2018 Amount sanctioned : 18 Lacs Funding agency : SAC (ISRO)

Saurashtra University, Rajkot i). Prof. Satya P. Singh, Professor & Head, Department of Biosciences

Field of Specialization  Diversity, Phylogeny &Biocatalytic potential of halophilic/haloalkaliphilic bacteria

 Hyperthermophilic bacteria /Protein Engineering: Structure & Function relationship

 Recombinant enzymes from haloalkaliphilic bacteria

 Metagenomics of Extreme Environment

ii). Dr. Rahul Kundu, Professor, Department of Biosciences Field of Specialization  Coastal Assemblages in rocky-muddy shores of coastal India, Diversity, distribution and ecology of intertidal macrofaunaof Indian coastline.

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 Applications of DNA Barcoding and Bioinformatics on the baseline taxonomic database of intertidal macrofauna

 Evolutionary Ecology and identification of Cryptic species in the rocky shores of Indian coastline by molecular phylogenetic tools

 Impact of anthropogenic pressure on the intertidal ecosystems

 Role of microorganism population in association with intertidal macrofauna and their biotechnological applications

iii). Dr. Ramesh Kothari, Professor, Department of Biosciences

Field of Specialization The findings of research studies pursued by us revealed the efficacy of genome reconstruction of hitherto unknown microbes from metagenomics datasets for individual species analysis in complex environments where the microflora plays a vital role. In our study on rumen metagenomics, variation in the abundance of a few glycosyl hydrolase family enzyme coding sequences reflected the metabolic significance of rumen-adapted Prevotellaruminicola species in utilization potential of coarse diet by these animals based on the acquisition of novel genetic elements. These findings open a gateway for developing strategies to facilitate in vitro growth of uncultivable microbes by exploring enzymes specific to environment specific species. And this will ultimately increase our knowledge of the 'Microbial Dark Matter' for numerous applications to improve the environment in the Gujarat areas at different aspects like the desert niche, air microbes, effluent areas and specifically genome study from metagenomics of bioreactors for waste treatments.

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 Laboratory experiments were undertaken to isolate and report several bacteria having potential to degrade and detoxify several PAHs efficiently along with toxic effects of PAHs by genotoxicity and cytotoxicity assay

 The detrimental effects of agrochemicals, PAHS and textile dyes on seed germination of several crops affecting its overall production were also part of studies.  We have also found novel genes and metabolic pathways by sequencing the whole genome of few novel bacterial isolates  We have also found that there are several agrochemical s and PAHs having toxic and mutagenic effect by the Ames test iv). Prof. H. H. Joshi, Professor & Head, Department of Physics Field of Specialization  Atmospheric Minor Constituents:  Aerosols study and its relevance with atmosphere

S. P. University, Vallabh Vidyanagar

 Dr. N. V. Shashtry,Professor, Department of Chemistry  Dr. T. V. Rammana Rao, Professor, Department of Bioscience  Dr. A. S. Reddy, Professor, Department of Bioscience  Dr. K. C. Patel, Professor, Department of Microbiology  Dr. N. K. Bhatt, Associate Professor, Department of Physics  and other faculty members would be involved/consulted/invited as and when the subjective requirements arises to meet the proposed objectives.

M. S. University of Baroda, Vadodara  Dr. Sarita Gupta, Professor, Department of Biochemistry  Dr. Rolee Kanchan, Professor, Department of Geography  Dr. Arun Arya, Department of Environmental Science

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 Dr. Chamiyal, Professor, Department of Geology  and other faculty members would be involved/consulted/invited as and when the subjective requirements arises to meet the proposed objectives. Maharaja Krishna Kumar Sinhji University, Bhavnagar i). Dr. Bharti P. Dave, Prof. & Head, Department of Biosciences Coordinator, ESTC, Ministry of Earth Science (MoES), New Delhi The research work is focused on various environmental aspects like

(a) Bioremediation of industrial effluents of textile dye industries, pulp and paper mill effluents that contain toxic molecules using bacteria and fungi

(b) Synthesis of bioplastics and their degradation using bacteria and fungi

(c) Biodegradation of hydrocarbons like crude oil and polycyclic aromatic hydrocarbons (which are the most carcinogenic molecules) in marine environment using bacteria and fungi.

Bioscience Department is supported by Ministry of Earth Sciences (MoES), Govt. of India, New Delhi as an Earth Science and Technology Cell (ESTC) on marine coastal ecology of West Coast of India. Since 2007.

The Ministry has sanctioned about 4 crores for various projects on Biodiversity and Pollution along the West Coast of India, as a Network Project involving 09 different institutions including Maharaja Krishna Kumar Sinhji Bhavnagar University, Central Salt & Marine Chemicals Research Institute, Bhavnagar, Gujarat University, M.S. University of Baroda, Saurashtra University, Gujarat Ecology Society, Javaharlal Nehru Technological University, Hyderabad, etc.

Besides financial support by MoES, we have also received grants from other funding agencies like DST, UGC, GSBTM, etc for projects on environmental pollution and bioremediation for keeping our oceans free of hazardous chemicals.

iii). Dr. Indra Gadhvi: Associate Professor and Head, Department of Marine Science, Mharaja Krishna Kumar Sinhji University, Bhavnagar

Hemchandracharya North Gujarat University, Patan Dr. Shreyas Bhatt, Professor and Head, Department of Biosciences

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Dr. Ila Patel, Associate Professor, Department of Biosciences Dr. Nishith Dharaiya, Associate Professor, Department of Biosciences 3) Definition and significance of research outputs/ deliverables-reports/papers, products /patent, software/ translation to state/national policy framework  Climate Change is burning issue which is causing serious implications in recent times. It is our collective responsibility to address this phenomenon before it’s too late.  Investigators from industry and academia have worked individually on several aspects of environmental issues with reference to biological, chemical and physical parameters of coastal diversity.  There is an urgent need to address these parameters with a common context of Climate Change Impacts and its Management to understand, maintain and safeguard our available coastal/shoreline diversity  The research outputs from this project would deliberate on relevance on inter- disciplinary components with specific changes and happening taking place.  The reports for inter-disciplinary research would focus on core issues of short term as well as long term changes  Future events could be forecasted to avoid or combat natural calamities or disaster  The research work would generate mammoth data to interpret, analyse and evaluate.  More than 15 Ph.D.’s and 30 M.Phil.’s can be produced out of these exhaustive investigations  More than 30 research papers of high quality data could be published  The analysis and evaluation would enable us to frame a comprehensive state policy to implement and safeguard current and future coastal/shoreline diversity

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4) Clarity of aims, objectives and research questions Keeping the above facts in mind, consideration the objectives are planned to address the shoreline diversity studies as: (i) Scouting and documentation of shoreline diversity (Flora & Fauna) and Identification of gap areas. (ii) Climate Change Impacts studies (Biological, Physical and Chemical parameters) and comparative evaluation of various components through field survey and Remote Sensing (iii) Introduction of a regional specific strategic model/s and action plan for development and conservation of existing shoreline diversity. (iv) Exploration of the possible application potential, such as Bioactive compounds, Nanomaterials and other useful molecules (v) Management of the human activities and tourism in the context of the Environmental preservation (vi) Study of atmospheric effects produced by natural and human origin aerosols, water vapour and ozone concentration

(vii) To study the role of chemical and dynamical processes on the distribution of O3 and its precursor gases over Gujarat Coast. (viii) Identification of source regions and quantification of their contribution towards pollution enhancement over the western Indian region. (ix) To investigate the dispersion of air pollutants emitted over polluted cities of western India and their impacts over the downwind locations. (x) To study the interaction of trace gases and aerosols and its effects on atmospheric chemistry. (xi) To study the temporal variation of atmospheric aerosols and its impact on the Earth’s climate.

Data/Information Requirement  Satellite derived data of biological, Physical and chemical parameters

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 Additional satellites derived relevant information and primary details  Available field data and published/unpublished information.

5) Methodology- innovativeness/originality and soundness/rigour The research would be having three sections studies like physical, chemical and biological parameters with reference to climate change impacts at 06 different universities. It will also include the aspects related to the management of the tourisms and other human activities.

The 06 proposed universities would coordinate for common parameters studies required for analysis and evaluation of the available primary records as well as comparative review of the work done so far.

Once the data compiled, then the final distribution of research work at each centre would be deliberated to networking university. Regular meetings and coordination is must to ensure proposed research goals and objectives. The central data analysis coordination would be encouraged by nodal university for necessary documentation and publication of work. The following state-of-the-art instruments will be used to achieve the objectives for atmospheric parameter study

6) Definition and significance/value of concrete outcomes Present project would develop an effective public education and outreach program to ensure community involvement and understanding. Based on the experience, developing Management Conference procedures and dedicating staff would result in sophisticated and significant efforts that highlight the value of the resource, raise awareness and support for actions needed to protect the shoreline. Some programs

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may utilize social marketing programs to elicit change and increase stewardship and knowledge of citizens so that they become stakeholders.

It will produce around 09 Post-Doctoral Fellows, around 15 Ph.D. and 30 M.Phil. Scholars. In addition to that the present is expected to produce more than 30 publications, 05 annual reports and final project report with ISBN. The scholars who will be involved in this project will also interact with the distinguished scientists working in this field. And they will get the opportunity to meet them in person, exchange scientific ideas and discuss on relevant field. This will be a platform to meet various scientists actively involved in shoreline diversity and oceanography field, certainly this interaction and exposure will help enhance the vision, enabling the scholars to perform and contribute in a better scientific way.

7) Interdisciplinary/multidisciplinary orientation and multi-institution networking Faculties from 06 net working universities from subjects like Climate Change, Physics, Botany, Biochemistry, Molecular Biology, Chemistry, Life Sciences and Microbiology etc. would coordinate for this project. The blue print of the project is to study physical, chemical and biological parameters as interdisciplinary approach. This would be first of its kind research where multidisciplinary research aspects would be addressed for concrete reasoning on common findings, which would ultimately suggested as policy to implement for conservation strategies and management of shoreline diversity. The “Centre for Climate Studies” would coordinate the research, development and maintenance of data for Western India 8) Anticipated outcome (s) of the proposal The primary goal and benefit from the Comprehensive Plan that is addressed by this proposal is to study & examine the shoreline diversity status and changes. An equally important and included goal and benefit is to Restore and Conserve diversity by adopting region specific models. Other secondary Comprehensive Plan goals and

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benefits addressed by this proposal include Restoring and Conserving diversity, Replenishing and Protecting Living Coastal and Marine Resources, Enhancing Community Resilience, and Restoring and Revitalizing the Gulf Economy.

Social impacts  Provide increased security from natural disasters (mangroves, corals, sea grasses, beeches, Sand dunes etc  Conservation habitats checks salinity ingression will enhance drinking water availability  Chances for enhanced livelihood development activities from coastal resources  Increased opportunities for economic development through non destructive ways such as conduct of tourism

Environmental impacts  Conservation of habitats/ecosystems enhances biodiversity  The ecosystems/habitats provide facility for roosting, spawning and breeding ground for many species both aerial and aquatic species  Checks salinity ingression and control disasters such as erosion, sea surges and cyclones  Enhances availability of resources such as fisheries, fodder, etc (mangroves, coral, sea grasses, mud banks, mudflats etc.)  Mudflats supports ecological succession towards halophytic vegetation

9) Research and Innovation culture creation among affiliated colleges  The research investigations are planned to deliberate more on orientation cum training programme at college located near to shores and coastal area.  The faculty and students from such colleges including local NGO’s would be involved in diversity studies.

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 Awareness programme and public participation would be encouraged through series of events for subject specific requirements.  Government – Academia collaborative programmes for implementation of important policies.  Promotion of academic activities to generate interest and responsibilities amongst the shoreline diversity.  Introduction of curriculum as certificate/diploma courses.  Marketability of products produced from shoreline diversity resources

Publications

Shukla R. and Singh S.P. 2015. Characteristics and thermodynamics of - amylase from thermophilic actinobacterium, Laceyellasacchari TSI-2. Process Biochemistry (In Press) (IF 2.63).

Kikani, B.A. and Singh S.P. 2015. Enzyme stability, thermodyanamics and secondary structures of -amylase as probed by the CD spectroscopy. International Journal of Biological Macromolecules (IJBIOMAC) 81,450-460 (doi: 10.1016/j.ijbiomac.2015.08.032) (IF 3.00).

Kikani, B.A., Sharma, A. and Singh S.P. 2015. Culture dependent diversity and phylogeny of thermophilic bacilli from a natural hot spring reservoir in the Gir Forest, Gujarat (India). Microbiology (Moscow, Russia), 84 (6), 00-00 (IF 0.80).

Shukla, R. and Singh, S.P. 2015.Production Optimization, purification and characterization of α-amylase from thermophilic Bacillus licheniformis TSI-14, Starch/Stärke 2015, 67,1 –11 (IF 1.40).

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Gohel, S. and Singh S.P. 2014. Thermodynamics of a Ca2+ dependent highly thermostable alkaline protease from a haloalkliphilicactinomycete.International Journal of Biological Macromolecules (IJBIOMAC). DOI: 10.1016/j.ijbiomac.2014.08.008 (IF 2.45).

Akbari,V.G., Pandya, R.D. and Singh S.P. 2014. Extraction of the metagenomic DNA and assessment of the bacterial div ersity from the petroleum-polluted sites. Environmental Monitoring and Assessment. DOI 10.1007/s10661-014-3859-6 (IF 1.6).

Joseph, S., Poriya, P., Vakani, V., Singh, S.P. and Kundu, R.S. 2014. Identification of a group of cryptic marine limpet species, Cellanakarachiensis (Mollusca: Patellogastropoda) off coast, India, using mtDNA COI sequencing. GDNA Mitochondrial DNA (In Press) (IF 1.8).

Purohit, M. and Singh S.P. 2014. Cloning, over expression and functional attributes of serine proteases from Oceanobacillusiheyensis O.M.A18 and Haloalkaliphilic bacterium O.M.E12, Process Biochemistry 49: 61-68 (IF 2.627).

Raval, V. Rawal, C.M., Pandey, S., Bhatt, H., Dahima, B. and Singh S.P. 2014. Cloning, heterologous expression and structural characterization of an alkaline serine protease from sea water haloalkaliphilic bacterium, Annals of Microbiology, (IF 1.5). doi:10. 1007/s13213-014-0869-0

Raval, V. Rawal, C.M., Pillai, S. and Singh S.P. 2014. Biochemical and structural characterization of a detergent stable serine alkaline protease from sea water haloalkaliphilic bacteria. Process Biochemistry 49 (6): 955-962 (IF 2.63)

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Complete Genome Sequence of Escherichia phage ADB-2 Isolated from Fecal Sample of Poultry, Genome Announcements (ASM, USA) 1(2): e00043-13. doi:10.1128/genomeA.00043-13

Gohel, S. and Singh S.P. 2013. Characteristics and thermodynamics of a thermostable protease from a salt-tolerant alkaliphilicactinomycete. International Journal of Biological Macromolecules (IJBIOMAC) 56: 20– 27 (IF 2.453).

Purohit, M. and Singh S.P. 2013. A metagenomic alkaline protease from saline habitat: cloning, over-expression and functional attributes. International Journal of Biological Macromolecules (IJBIOMAC) 53: 138– 143 (IF 2.50).

Kikani, B.A., Pandey, S. and Singh S.P. 2012. Bioprocess and Biosystems Engineering - BPBSE 36(5): 567-577 (IF 1.80).

Rawal, C. M., Raval V. H., Bhimani, H. D., Bhensdadia D. V., Kothari, C. R. , Patel A. B., Bhatt, V. D., Parmar, N. R., Sajnani M. R., Koringa, P. G., Joshi, C. G., Kothari, R. K. and S. P. Singh, S.P. 2012. Journal of Bacteriology, J. Bacteriol. 194(17): 4775 (IF 3.82).

Sharma, A.K., Gohel, S. and Singh S.P. 2012. Bioinformation, 8 (11):535-538 (IF 1.12).

Kikani, B.A. and Singh S.P. 2012. Process Biochemistry, 47: 1791-1798 (IF 2.64).

Pandey, Sandeep, Rakholiya, K. Raval V.H. and Singh S.P. 2012. Journal of Bioscience and Bioengineering, 114 (3), 251-256 (IF 1.70).

Pandey, Sandeep and Singh S.P. 2012. Appl. Biochemistry and Biotechnology, 166:1747- 1757. (IF 1.87).

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Gohel, S. and Singh S.P. 2012. J Chromatography-B,889– 890, 61– 68 (IF 2.97).

Gohel, S. and Singh S.P. 2012. International Journal of Biological Macromolecules (IJBIOMAC) 50: 664– 671 (IF 2.50).

Purohit, M. and Singh S.P. 2011. International Journal of Biological Macromolecules (IJBIOMAC), 49:103–112 (IF 2.50).

Kikani, B. and Singh S.P. 2011. International Journal of Biological Macromolecules (IJBIOMAC) 48: 676–681 (IF 2.50).

Ukani, H. Purohit, M., Georgge, J. and Singh, S.P. 2011. Journal of Scientific &Industrila Research, CSIR (IF 0.51)

Surani, J., Akbari, V., Purohit, M., and Singh, S.P. 2011. Journal of Bioremediation and Biodegradation: 2-1(IF 1.20)

Jis Joe, R. K. Kothari, C.M. Raval1, C.R. Kothari, V. G. Akbari and S. P. Singh.2011. Journal of Bioremediation and Biodegradation, 2-2. (IF 1.20)

Singh S.P., M.K. Purohit, C. Aoyagi, M. Kitaokaand K. Hayashi. 2010. Biotechnology Bioprocess Engineering 15 (2):273-276 (IF 1.00).

Karan Ram, Singh S.P, Kapoor S., M. Khare, S.K., 2010. New Biotechnology doi:10.1016/j.nbt.2010.10.007(IF 1.84).

Siddhapura P. K., Vanparia S., Purohit, M. and Singh S.P. 2010. International Journal of Biological Macromolecules (IJBIOMAC) 47: 375–379 (IF 2.50).

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Vaghela A., Bhadja P., Ramoliya J., Patel N., and Kundu R. (2010). Seasonal variations in the water quality, diversity and population ecology of intertidal macrofauna at an industrially influenced coast. Journal of Water Science and Technology, 61 (6): 1505- 1514.

Gohil. B. and Kundu, R. (2011). Ecological status of Rhinoclavissinensis at Dwaraka coast, Gujarat (India). The Ecoscan, 5 (3 & 4): 131-134.

Bhadja, P. and Kundu R. (2012). Status of the seawater quality at few industrially important coasts of Gujarat (India) off Arabian Sea. Ind. J. Geo-Mar. Sci., 41(1) 954-961.

Vaghela A. and Kundu R. (2012). Spatiotemporal variations of hermit crab (crustacea :decapoda) inhabiting rocky shore along Saurashtra coast, western part of India. Ind. J. Geo-. Sci. 41(2): 146-151.

Gohil, Bharatsinh,Kundu, Rahul. (1013) Ecological status of Cerethiumcaeruleum at Dwarka coast, Gujarat (India). Indian J. Geo-Marine Science, 42(4): 481-486

Faladu, J, Vakani, B., Poriya, P. and Kundu, R. (2014). Habitat preference and population ecology of limpets Cellanakarachiensis (Winckworth) and Siphonariasiphonaria (Sowerby) at Veraval coast of Kathiawar Peninsula, India. J. Ecosystem. Volume 2014, Article ID 874013, 6 pages.

Sneha Joseph, Poriya, P., Vakani,B., Singh, S.P. and Kundu, R. (2014). Identification of a group of cryptic marine limpet species, Cellanakarachiensis (Mollusca: Patellogastropoda) off Veraval coast, India, using mtDNA COI sequencing. Mitochondrial DNA. Early Online, August 11, 2014. DOI:10.3109/19401736.2014.945577 (IF-1.71)

PoonamBhadja, PareshPoriya, and Rahul Kundu (2014). Community Structure and Distribution Pattern of Intertidal Invertebrate Macrofauna at Some Anthropogenically Influenced Coasts of Kathiawar Peninsula (India). Advances in Ecology, Volume 2014, Article ID 547395, pp. 1-11.

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Sneha Joseph, Poriya, P., Vakani, B., and Kundu, R. (2014). Probing the phylogenetic relationships of a few newly recorded intertidal zoanthids of Gujarat coast (India) with mtDNA COI sequences. Mitochondrial DNA. Early Online, October, 2014. DOI: 10.3109/19401736.2014.971239, (IF-1.71).

Poriya P. and Kundu, R. (2014). Species invasion and succession as community and Ecosystem responses towards climate change in the Rocky intertidal ecosystems of Kathiawar peninsula. Journal of Aquatic Biology and Fisheries, 2: 426-430.

Effect of roughage on rumen microbiota composition in the efficient feed converter and sturdy Indian Jaffrabadi buffalo (Bubalusbubalis). Neelam M Nathani, Amrutlal K Patel, Mootapally Chandra Shekar, Bhaskar Reddy, Shailesh V Shah, Pravin M Lunagaria, Ramesh K Kothari, Chaitanya Joshi. BMC Genomics.(Accepted) . (Impact factor: 399)

Correlation between Genomic analyses with Metatranscriptomic study reveals various functional pathways of Clostridium sartagoforme AAU1, a buffalo rumen isolate. Neelam M. Nathani, Srinivas M. Duggirala, Vaibhav D. Bhatt, Amrutlal K Patel, Ramesh K. Kothari, Chaitanya G. Joshi. Journal of Applied Animal Research. DOI: 10.1080/09712119.2015.1091346 (Impact factor: 0.435)

Synthesisand Microbial Evaluation of Versatile Base Catalyzed Chiral Tetrahydrobenzofuran Derivatives via Multicomponent Reaction. KhushalKapadiya, RohitKotadiya, KishorKavadia, Ramesh Kothari, KrunalMehariya and RanjanKhunt. Letters in Drug Design & Discovery. (Impact factor: 0.77)

Correlation between genomic analysis with metatranscriptomic study reveals various functional pathways of Clostridium sartagoforme AAU1, a buffalo rumen isolate. Neelam M. Nathania, Srinivas M. Duggirala, Vaibhav D. Bhatt, Amrutlal K. Patel,

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Ramesh K. Kothari & Chaitanya G. Joshi. Journal of Applied Animal Research. 44(1) 498-507 (2015).

Catalyst free synthesis of thiazole derivatives bearing azo imine linkageas antimicrobial agents. Khushal Kapadiya1, KishorKavadia, ParthManvar, RohitKotadiya, Ramesh Kothari and RanjanKhunt. Chemistry & Biology Interface. 5(4) 258 – 266 (2015).

Functional Characterization Reveals Novel Putative Coding Sequences in Prevotellaruminicola Genome Extracted from Rumen Metagenomic Studies. Neelam M. Nathania, Ramesh K. Kothari, Amrutlal K. Patel, Chaitanya G. Joshi. J MolMicrobiolBiotechnol 2015; 25:292–299 (2015). (Impact factor: 2.104)

Isolation of chitinolytic Clostridium sp. NCR from Mehsani buffalo rumen, its genomic analysis and potential role in rumen, Neelam M. Nathani, Srinivas M. Duggirala , Chandra Shekar M. , Ramesh K. Kothari, Chaitanya G. Joshi , Genomics Data 5, (2015) 109–111. (May 2015) Fuse binding protein antagonizes the transcription activity of tumor suppressor protein p53.Updesh Dixit, Zhihe Liu, Ashutosh K Pandey, Ramesh Kothari and Virendra N Pandey. BMC Cance. 14:925 http://www.biomedcentral.com/1471-2407/14/925 (Bio MEd Central) (2014).

Optimization of Parameters for Decolorization of a Textile azo dye, Remazol Black B (RBB) by a Newly Isolated Bacterium, Bacillus thuringiensis BYJ1. Joshi, A. Y.; Kothari, V. V.; Kothari, C. R.; Bhimani, H. D.; Kothari, R. K.; African Journal of Microbiology Research., 2014, 8(47), 3837 – 3849 (2014). (Impact factor: 0.54)

Isolation, Molecular Characterization and Insight into the Genome Sequence of E. coli Bacteriophage ADB-2 from Poultry Fecal Sample. Bhensdadia, D.V.; Bhimani, H.D.;

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Nathani, N.M.; Rawal, C.M.; Koringa, P.G.; Joshi, C.G.; Kothari, C.R.; Kothari RK, Next Generation Sequencing & Application, 2014, 1(1), 1000101 (OMICS)

Biodegradable gelatin–ciprofloxacin–montmorillonite composite hydrogels for controlled drug release and wound dressing application. Kevadiya, B.D.; Rajkumar, S.; Bajaj, H. C.; Chettiar, S.S.; Gosai, K.; Brahmbhatt, H.; Bhatt, A.S.; Barvaliya,Y.K.; Dave,G.S.; Kothari, R.K.; Colloids and Surfaces B: Biointerfaces, 2014, 122, 175–183 (Elsevier)(Impact factor: 4.187)

Influence of some chemical parameters on decolorization of textile dyes by bacterial strains isolated from waste water treatment plant. Bhimani, H. D.; Bhensdadia, D. V.; Rawal, C. M.; Kothari, V. V.; Kothari, R. K.; Kothari, C. R.; Bhimani, G. C.; African Journal of Microbiology Research, 2014, 8(11), 1213-1220 (Academic Journals) (Impact Factor: 0.65)

Study of rumen metagenome community 6 using qPCR under different diets.Singh, K.M.; Pandya, P.R.; Tripathi, A.K.; Patel, G.R.; Parnerkar, S.; Kothari, R.K.; Joshi, C.G.; Meta Gene, 2014, 2, 191–199 (Elsevier)

Draft Genome Sequence of the Potential Probiotic Bacterium LactobacilliusrhamnosusLr 231.Ambalam,P.; Pithva, S.; Kothari, C.R.; Kothari, R.K.; Parmar, N.R.; Nathani, N.M.; Koringa, P.G.; Joshi, C.G.; Dave, J.M.; Vyas, B.M.; Genome Announcements, 2014, 2(1), e00111-14 (ASM)

Draft Genome Sequence of Petroleum Hydrocarbon Degrading Pseudomonas aeruginosa strain PK6 Isolated from Saurashtra Region of Gujarat, India.Patel, P.A.; Kothari, V.V.; Kothari, C.R.; Faldu, P.R.; Domadia, K.K.; Rawal, C.M.; Bhimani, H.D.; Parmar, N.R.; Nathani, N.M.; Koringa, P.G.; Joshi, C.G.; Kothari, R.K.; Genome Announcements, 2014, 2(1), e00002-14 (ASM)

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Draft Genome Sequence of Textile Azo Dye Decolorizing and Degrading Pseudomonas aeruginosa strain PFK10 Isolated from CTETP of Ankleshwar Industrial Area of Gujarat, India. Faldu, P.R.; Kothari, V.V.; Kothari, C.R.; Rawal, C.M.; Patel, P.A.; Domadia, K.K.; Bhimani, H.D.; Raval, V.H.; Parmar, N.R.; Nathani, N.M.; Koringa, P.G.; Joshi, C.G.; Kothari, R.K.; Genome Announcements, 2014, 2(1), e00019-14.(ASM)

Molecular diversity of protozoa in rumen of Indian buffalo (Bubalusbubalis).Singh, K. M.; Pandya, P. R.; Tripathi, A. K.; Patel, G. R.; Parnerkar, S.; Kothari, R. K.; Joshi, C. G.; Agricultural Research, 2013, 2(4), 360–366 (Springer)

Genome Sequence of Salt-Tolerant Bacillus safensis Strain VK, isolated from Saline Desert Area of Gujarat, India. Kothari, V. V.; Kothari, R. K.; Kothari, C. R.; Bhatt, V. D.; Nathani, N. M.; Koringa, P. G.; Joshi, C. G.; Vyas, B. R. M.; Genome Announcements, 2013, 1(5), e00671-13 (ASM)

Comparative Evaluation of Rumen Metagenome Community using qPCR and MG- RAST.Nathani,N.M.; Patel,A.K.; Dhamannapatil, P.S.; Kothari, R.K.; Singh,K.M.; Joshi, C.G.; AMB express, 2013, doi:10.1186/2191-0855-3-55 (Springer)

Histology and Histomorphology of Hormone Treated Surati Buffalo Udder Tissue. Mehta, H.H.; Patel, A.K.; Nandasana, K.N.; Ramani, U.V.; Koringa, P.G.; Shah, R.G.; Barvalia, D.R.; Kelawala, N.; Patil, D.B.; Rank, D.N.; Joshi, C.G.; Panchal, K.M.; Kothari, R.K.; American Journal of Animal and Veterinary Sciences, 2013, 8(2), 66-72 (Science publications) (Impact factor: 0.65)

Use of Real-Time PCR Technique in Determination of Major Fibrolytic and non Fibrolytic Bacteria Present in Indian Surti Buffaloes (Bubalusbubalis). Singh, K.M.; Tripathi,A.K.; Pandya,P.R.; Parnerkar,S.; Rank,D.N.; Kothari,R.K.; Joshi, C.G.; Polish

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Journal of Microbiology, 2013, 62(2), 195-200, (Polish Society of Microbiology) (Impact Factor: 0.76)

Molecular Genetic Diversity and Quantitation of Methanogen in Ruminal Fluid of Buffalo (Bubalusbubalis) Fed Ration (wheat straw and concentrate mixture diet). Singh, K.M.; Tripathi, A. K.; Pandya,P.;Kothari, R. K.; Joshi, C. G.; Genetics Research, 2013, 2013, Article ID 980191 (Hindawi Publishing Corporation)

Complete Genome Sequence of Escherichia Phage ADB-2 Isolated from a Fecal Sample of Poultry.Bhensdadia, D. V.; Bhimani, H. D.; Rawal, C. M.; Kothari, V. V.; Raval, V. H.; Kothari, C. R.; Patel, A. B.; Bhatt, V. D.; Parmar, N. R.; Sajnani, M. R.; Koringa, P. G.; Joshi, C. G.; Singh, S. P.; Kothari, R. K.; Genome Announcements, 2013, 1(2), e00043-13 (ASM)

The Effect of Hormone Treatment on Dry Surati Buffalo Mammary Gland.Mehta, H.H.; Patel, A.K.; Nandasana, K.N.; Ramani, U.V.; Koringa, P.G.; Shah, R.G.; Barvalia, D. R.; Kelawala, N.H.; Rank, D.N.; Joshi, C.G.; Panchal, K.M.; Kothari, R.K.; International Journal of Pharma and Bio Sciences, 2013, 4(1), 298-308 (Elsevier)

Metagenomic Analysis of Surti Buffalo (Bubalusbubalis) Rumen: A Preliminary Study. Singh, K.M.; Ahir,V.B.; Tripathi, A.K.; Ramani, U.V.; Sajnani, M.; Koringa, P.G.; Jakhesara, S.; Pandya, P.R.; Rank, D.N.; Murty, D.S.; Kothari, R.K.; Joshi, C.G.; Molecular Biology Reports, 2012, 39, 4841–4848 (Springer) (Impact factor: 2.93)

Whole-Genome Shotgun Sequencing of the Extremophile Alkalibacillushaloalkaliphilus C-5, of Indian Origin.Rawal, C. M.; Raval, V. H.; Bhimani, H. D.; Bhensdadia, D. V.; Kothari, C. R.; Patel, A. B.; Bhatt, V. D.; Parmar, N. R.; Sajnani, M. R.; Koringa, P. G.; Joshi, C. G.; Kothari, R. K.; Singh, S. P.; Journal of Bacteriology, 2012, 194(17), 4775 (ASM) (Impact factor: 3.924)

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Methanogen Diversity in the Rumen of Indian Surti Buffalo (Bubalusbubalis) Assessed by 16S rDNA Analysis. Singh, K.M.; Tripathi, A.K.; Pandya, P.R.; Parnerkar, S.; Rank, D.N.; Kothari, R.K.; Joshi, C.G.; Research in Veterinary Science, 2012, 92, 451–455 (Elsevier) (Impact factor: 1.72)

Decolorization of Textile Dye Remazol Black B by Pseudomonas Aeruginosa CR-25 isolated from the Common Effluent Treatment Plant.Joe,J.; Kothari, R. K.; Raval, C.M.; Kothari, C.R.; Akbari, V. G.; Singh, S. P.; Journal of Bioremediation & Biodegradation, 2011, 2(2),1000118 (OMICS)(Impact factor: 3.5)

Protective Effect of Lactobacillus rhamnosus 231 against N-Methyl-N'-nitro-N- nitrosoguanidine in Animal Model.Gosai,V., Ambalam, P.; Raman,M.; Kothari, C.R.; Kothari, R.K.; Vyas, B.R.M.; Sheth, N.R.; Gut Microbes, 2011, (2)6, 319-325 (Landes Bioscience)

Dasytricha Dominance in Surti Buffalo Rumen Revealed by 18S rRNA Sequences and Real-Time PCR Assay. Singh, K. M.; Tripathi, A. K.; Pandya, P. R.; Rank, D. N.; Kothari, R. K.; Joshi, C. G.; Current Microbiology, 2011, 63, 281-288 (Springer) (Impact factor: 1.52)

Molecular Identification if Methanogenic Archaea From Surti Buffaloes (BubalusBubalis), Reveals More HydrogenotrophicMethanogensPhylotypes. Singh, K.M.; Pandya, P.R.; Parnerkar, S.; Tripathi, A.K.; Rank, D.N.; Kothari, R.K.; Joshi, C.G.; Brazilian Journal of Microbiology, 2011, 42, 132-139 (SMB) (Impact factor: 0.90)

Methanogenic Diversity Studies within the Rumen of Surti Buffaloes Based on Methyl Coenzyme M Reductase A (mcrA) Genes, Point to Methanobacteriales.Singh, K.M.; Pandya, P.R.; Parnerkar, S.; Tripathi, A.K.; Ramani,U.; Koringa, P.G.; Rank, D.N.; Joshi,

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C.G.; Kothari, R.K.; Polish Journal of Microbiology, 2010, (59)3, 175-178 (Polish Society of Microbiology) (Impact factor:0.76)

Bacterial Diversity in the rumen of Indian Sutri buffalo (Bubalusbubalis), 16S rDNA Sequences analysis Approach. Journal of Applied Genetics.Pandya, P.R.; Singh, K. M.; Tripathi, A.K.; Mehta, H.H.; Rank, D.N.; Parnerkar,S.; Kothari, R. K.; Joshi,C.G.; Journal of Applied Genetics, 2010,(51) 3, 395-402 (Springer) (Impact factor: 1.847)

Decolorization of Textile Dyes and its Effect on Seed Germination.Vora, V.; Kothari, R. K.; Kothari, C. R.; The FASEB Journal- The Journal of the American Societies for Experimental Biology, 2007, ISSN: 0892-6638 (Springer) (Impact Factor:5.704)

Decolorization of textile azo dyes by a three member bacterial consortium. Kothari, R. K.; Kothari, C. R.; Int. J. Bioscience Reporter, 2006, 4(1), 21-26. (Bioscience Guardian)

MNP and MIP mediated decolorization of textile dyes Reactive Red 22 and Reactive Black 5. Kothari, R. K.; Trivedi B. B.; Jhala V. M.; Pathak S. S.; Joshi, M. M.; Int. J. Bioscience Reporter, 2006, 24(2), 307-312 (Bioscience Guardian)

Assessment of Antimicrobial activity of various GutkhaAgainst the Normal Flora of Human Oral Cavity.Kothari, R. K.; Mavani, M.D.; Vidja, K.G.; Joshi, M.; Vanjara, N.; Advances in Pharmacology & Toxicology, 2006, 7(3), 0973-2381

Microbial Decolorization and degradation of textile dyes Golden-HR and Meganta-HB. Kothari, R. K.; Kothari C. R.; Pathak, S. J.; Asian Jr. Microbiol. Biotech. Env. Sc., 2006, 7(2), 239-242

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Decolorization of textile dyes by ligninolytic enzymes of white rot fungus Coriolopsispolysona.Kothari R. K.; Kothari C. R.; Pathak, S. J.; Pollution Research, 2005, 24(2), 367-370 (Enviro Media)

Formation of Gum Ducts in Ailanthus excels in Response to Fungal Infection. Rajput, K.S.; Kothari, R.K.; Phyton, 2005, 45, 33-43 (Impact Factor:0.83)

Screening of heavy metal (sodium arsenate) resistance bacterial populations.Kothari, R. K.; Pathak, S. J.; Int. J. Bioscience Reporter, 2005, 3(2), 190-193 (Bioscience Guardian)

Rhodovulumaestuarii sp. nov., isolated from a brackish water body. Divyasree, B, Lakshmi KVNS, Bharti Dave ,SasikalaCh, RamanaCh.V. Int J SystEvolMicrobiol

Ramaprasad E.V.V., Bharti Dave, SasikalaCh, RamanaCh.V. (2015) Zooshikellamarina sp. nov.acycloprodigiosin and prodigiosin producing marine bacterium isolated from beach sand,Int J SystEvolMicrobiol

Vala AK, Dave BP. (2015) Explorations on marine -derived fungi for L-Asparaginase: Enzyme with anticancer potential. CurrCheBiol 9(1): 66-69. DOI: 10.2174/2212796809666150817195019

Shivani Y, Subhash Y, Dave BP, Sashikala Ch. RamanaCh.V (2015) Bacilluscrescens sp. nov., isolated from soil, Int J SystEvol Microbiology. (Accepted).

Dhangdhariya JH, Dubey S, Trivedi HB, Pancha I, Bhatt JK, Dave BP, Mishra S (2015) Polyhydroxyalkanoate from marine Bacillus megaterium using CSMCRI’s Dry Sea Mix as a novel growth medium, Int J BiolMacromol. 76 :254-261.

Bhatt JK, Ghevariya CG, Dudhagara DR, Rajpara RK, Dave BP (2014) Application of response surface methodology for rapid chrysene biodegradation by newly isolated marine-derived fungus Cochlioboluslunatus strain CHR4D, J Microbiol52(11): 908-917.

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Dave BP, Ghevariya CG, Bhatt JK, Dudhagara DR, Rajpara RK (2014) Enhanced biodegradation of total polycyclic aromatic hydrocarbons (TPAHs) by marine halotolerant Archromobacterxylosoxidans using Triton X-100 and β-cyclodextrin – A microcosm approach, Mar Pollut Bull 79(1-2): 123-129.

Ghevariya CG, Bhatt JK, Dave BP (2011) Enhanced chrysene degradation by halotolerant Achromobacterxylosoxidans using response surface methodology, BioresourTechnol102(20): 9668-9674.

Vyas TK, Dave BP (2011) Production of biosurfactant by Nocardiaotitidiscaviarum microbial type culture collection 6471 and its role in biodegradation of crude oil, Int J Environ Sci Tech 8(2): 425-432.

Rajpara RK, Dudhagara DR, Bhatt JK, Ghevariya CG, Dave BP (2015) Enhanced chrysene degradation by a mixed culture Biorem-CGBD using response surface design, Ind J ExpBiol, Ind J Exp Biol. 53(5):256-63

Vala AK, Trivedi HB, Dhangadahriya JH, Dave BP (2014) Marine-derived fungal siderophores : a perception, Indian J Mar Sci.Manuscript Accepted.

Soni AH, Dave BP, Hajela PS (2012) Synthesis and Characterization of PHB by Haloarcula sp. AB19 isolated from salt pans around Bhavnagar coast, J Pure ApplMicrobiol 6(4): 1735-1743.

Negi BS, Dave BP, Agarwal YK (2012) Evaluation of antimicrobial activity of Bauhinia purpurea leaves under in vitro conditions, Ind J Microbiol Manuscript Accepted.

Hajela P, Dave BP (2011) Diversity in Rhizosphere Fungi of Local Crop Plants around Bhavnagar (Guj) and their Siderophore production, J Pure ApplMicrobiol, 5(2): 705-716.

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NeeraChaturvedi, Meghal Shah, Ajai, Himanshu Pandya “Climate change and biological productivity:Indian Ocean ”, Advaces in Space science Research (Submitted)

Meghal Shah, NeeraChaturvedi, Ajai, HImanshu Pandya “Chlorophyll variability in the Indian Ocean in relation to Climate Change through Remotely Sensed data”, International Journal of Remote Sensing(Communicated)

Meghal Shah, NeeraChaturvedi, Y T Jasrai&Ajai“Chlorophyll Variability in the Arabian Sea and Bay of Bengal during last decade (1997-2007)” Indian Journal Geomatics,October,2012, Vol.6 No.2, 127-131.

NeeraChaturvedi, Meghal Shah, Ajai, Y T Jasrai“Is there impact of climate change on biological productivity in the Indian Ocean” Indian Journal Of Geo Marine Sciences,February,2013, Vol.42(1),50-57.

Atlas “Chlorophyll Atlas of Indian Ocean” -2012, NeeraChaturvedi&Ajai- SAC – ISRO, Ahmedabad, Meghal Shah & Y T Jasrai – Botany Department, Gujarat University,Ahmedabad

Dhara O. Bhavsar, Yogesh. T. Jasrai, Himanshu Pandya, Vijay Singh, Ajay Patel, and Manik H. Kalubarme (2014) Monitoring Mangrove Status using Remote Sensing andGeo-informatics in Piram Island, Gulf of Khambhat, Gujarat State, India, International Journal of Scientific and Engineering Research.

Bhavsar D. O., Jasrai Y. T. and Pandya H.A. (2013) The Impact of Aquaculture on Indian Mangroves Ecosystem: A Case Study of Olpad Taluka, Surat, India, International Journal of Recent Scientific Research, 4(12), 2016-2020

Rastogi R G, M E James & D Tripathi, Longitudinal inequalities in equatorial ionospheric electric filed, Ind J Radio & Space Phys (ISSN:0367-8393), 25, 27-35 Feb 1996.

M E James, D Tripathi & R G Rastogi, Day-to-day variability of ionospheric current system, Ind J Radio & Space Phys, (ISSN:0367-8393) 25 36-43 Feb 1996.

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R G Rastogi, H Chandra & M.E James, Nocturnal variations of geomagnetic horizontal filed at equatorial stations, Geophy Res Letters (USA), (ISSN: 1944-8007), 23 (No.19) 2601-2604 Sep 1996.

R G Rastogi, H Chandra & M E James, On the disintegration of the vortex structure of ionospheric current system along Asian longitude sector, J Geomag & Geoelectr (Japan), (ISSN: 0022-1392), .48 1481-1488 1996.

M E James, R G Rastogi & D R K Rao, Identification of the current system associated with a partially reversed equatorial electrojet, J Geomag & Geoelectr (Japan), (ISSN: 0022-1392). 49 633-640 1997.

M E James & R G Rastogi, Day-to-day variations of geomagnetic declination in Indo-Russian longitude sector, Indian J Radio & Space Phys, (ISSN:0367-8393), 26 332- 339 Dec 1997.

R G Rastogi & M E james, Geomagnetic field variations at equatorial electrojet observatory, Ettaiyapuram, Indian J. Radio & Space Phys, (ISSN:0367-8393), 30 221- 232 Oct 2001

R G Rastogi, D E Winch & M E James, Longitudinal effects in geomagnetic disturbances at mid-latitudes, J. of Earth Planet & Space (Japan), (ISSN: 1880-5981), 53, No.10, 969-979, 2001

M E James & R G Rastogi, Critical study of the Solar Daily Range of Geomagnetic H Field at Indo-Russian Chain of Stations, J of Indian Geophy. Union, (ISSN: 0257-7968), Vol. 6, No.4, pp. 187-194, Oct 2002

M E James, R G Rastogi & D E Winch, Magnetic Disturbance Effect on Eastward Geomagnetic Field, IJRSP, (ISSN:0367-8393) Vol. 33, April, 2004, 88-94.

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Rastogi R.G, K. Yumoto, M. E. James, K. Kitamura, Geomagnetic storm effects at equatorial electrojet stations, J. of Indian Geophy. Union, (ISSN: 0257-7968) Vol. 8, No.4, pp. 295-303, Oct 2004.

M.E. James, R.G. Rastogi & H. Chandra, Day-to-day variation of geomagnetic H filed and equatorial ring current, J. of Indian Geophy. Union, (ISSN: 0257-7968), Vol. 12, No. 2, PP 63-71, 2008.

R. G. Rastogi, H. Chandra, M. E. James, K. Kitamura and K. Yumoto, Characteristics of the equatorial electrojet current in the central region of South America, Earth Planets Space (Japan), (ISSN: 1880-5981), 60, 623–632, 2008.

Namrata Rajput, Hiren Dave, M.E. James, Kamaljit Ray and B. Simon, Study of intense rainfall over Gujarat during monsoon 2011 with special reference to offshore trough, Vayumandal (ISBN 09701397), Vol. 38, pp 11-25, 2012

Nisha Vaghmaria, Niyati Mevada and James Maliakal, Impact of Diwali Festival on Aerosol Characteristics over an Urban City, Ahmedabad (India), Under review in Aerosol and Air Quality Research.

Hiren Dave and M.E. James, Trends in intense rainfall events over Gujarat State (India) in the warming environment using gridded and conventional data, Communicated to Atmospheric Science Letters (Royal Met Society)

Bytnerowicz and Fenn, M., Nitrogen deposition in California forests: a review. Environ. Pollut., 1996, 92, 127-146.

Chand, D. and Lal, S. (2004), High ozone at rural sites in India, Atmos. Chem. Phys. Discuss., 4, 3359-3380, doi:10.5194/acpd-4-3359-2004.

IPCC, 2013: Climate Change 2013: The Physical Science Basis. Contribution of Working Group I to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change [Stocker, T.F., D. Qin, G.- K. Plattner, M. Tignor, S.K. Allen, J. Boschung, A. Nauels, Y. Xia, V. Bex and P.M. Midgley (eds.)]. Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA, 1535 pp, doi:10.1017/CBO9781107415324.

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Lal, S., and M. G. Lawrence (2001), Elevated mixing ratios of surface ozone over the Arabian Sea, Geophys. Res. Lett., 28(8), 1487–1490, doi:10.1029/2000GL011828.

Naja, M., and S. Lal (1996), Changes in surface ozone amount and its diurnal and seasonal patterns, from 1954–55 to 1991–93, measured at Ahmedabad (23 N), India, Geophys. Res. Lett., 23(1), 81–84, doi:10.1029/95GL03589.

Pope, C.A., Dockery, D.W., Health Effects of Fine Particulate Air Pollution: Lines that Connect; J. Air & Waste Manage. Assoc. 2006, 56,709–742.

Srivastava, S., S. Lal, M. Naja, S. Venkataramani and S. Gupta (2011), Influences of regional pollution and long range transport to western India: Analysis of ozonesonde data, Atmos. Environ. 47, 174-182.

Watson, J.G. Critical Review—Visibility: Science and Regulation; J. Air & Waste Manage. Assoc. 2002, 52, 628-713.

163 Gujarat State Higher Education Plan 2015-16 Annexure: 8 FOR DEPARTMENT OF POST DOCTORAL STUDIES AT SAURASHTRA UNIVERSITY, RAJKOT UNDER RUSA PROGRAMME

(TO BE SUBMITTED TO KCG, GOVT. OF GUJARAT)

1. Name of the Department: Department of Chemistry, Saurashtra University, Rajkot 2. Research Background: Department of Chemistry offers two programmes namely M. Sc. (four specialization and also dissertation) and Ph. D. The areas of research are Synthetic Organic and Medicinal Chemistry, synthesis of bioactive heterocycles, Drug discovery, Synthetic Polymers and their characterization, Composites and coating materials, Ultrasonic study of organic and polymeric solutions, Metal complexes and metal chelates, Liquid crystals, Method development and validation, Bioinformatics, etc. 3. User Principal Investigator: Prof.H.S. Joshi Professor Department of Chemistry Saurashtra University, Rajkot

Co- Principal Investigator: Prof. S.H. Baluja Department of Chemistry, Saurashtra University, Rajkot

Requirement of Project Fellow and RA: 1. Project Fellow: 06 2. RA: 06

Requirement of Equipments: 1.1H NMR 800 MHz :Rs. 200 lakhs 2. LC-MS-MS: 175 lakhs

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Major Achievements of the Department: Core faculty members of Department of Chemistry

DST-FIST Level II (2011-2016) and UGC-DSA-I (2015-2020) Sponsored and Centre of Excellence in Drug Discovery by Industries Commissionirate , Gov. of Gujarat 2014-2019 and NAAC Accredited with “A” Grade)

Name of Designation Age Qualification Research Area PhDs Faculty Produced Member

Dr. P.H. Professor and 61 MSc, Ph.D. Physical and Synthetic 10 Parsania Head Polymers

Dr. Anamik Professor 61 MSc, PhD Synthetic and Medicinal 17 Shah(V.C. Chemistry Gujarat Vidhypith)

Dr. V.H. Shah Professor 60 MSc, PhD Synthetic and Medicinal 12 Chemistry

Dr. H.S. Joshi Professor 53 MSc, PhD Synthetic and Analytical 09 Chemistry

Dr. S.H. Baluja Professor 42 MSc, PhD Synthetic Organic and 07 Physical Chemistry

Dr. U.C. Bhoya Associate 51 MSc, PhD Synthetic organic and Liquid 01 Professor Crystals

Dr. M.K. Shah Assistant 49 MSc, , PhD Metal complexes, Chelates 03 Professor and Bio-inorganic Chemistry

Dr. Y.T. Assistant 42 MSc, PhD Synthetic Organic Chemistry 08 Naliapara Professor and Medicinal Chemistry

Dr. R.C. Khunt Assistant 36 MSc, PhD Synthetic organic and 02 Professor medicinal Chemistry

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Distinction earned by faculty members

Dr. P.H. Parsania, Head of the Department

1. Coordinator – DSt-FIST, Saurashtra University, Rajkot 2. Member and advisor for various selection committee in various University and National Bodies. 3. Nominated as an expert in the field of petrochemicals and Fertilizer. 4. Member –Board of Studies, Saurashtra University, Rajkot 5. Member –Board of Studies in M.S. University, Panel of selection committee in various universities. 6. Co-coordinator – UGC sponsored Refresher Course in Chemistry at Saurashtra University, Rajkot 7. Judge-for Best poster paper presentation award in national and International level conference. 8. Invited talk, Resource person and Session Chairmen at the National and International in various conference in India and Abroad. 9. Fellow of Indian Chemical Society. 10. Peer reviewer of various National and International Scientific Journals. 11. Member Advisory Board, J. of Polymer materials. 12. Editor, Applied Journal Chemistry. 13. Member of Editorial Board, in various National and International journals and peer reviewer books published by various publishers. 14. Visited various countries.

Dr. Anamik K. Shah

1. Chairmen of NACC Peer review team. 2. Member and advisor for various selection committee in various University and National Bodies. 3. Nominated as an expert in the field of synthetic and medicinal chemistry. 4. President of Indian Society of Chemist and Biologist. 5. Member –Board of Studies in M.S. University, Panel of selection committee in various universities. 6. Co-coordinator Center of Excellence for Drug Discovery, Saurashtra University, Rajkot. 7. Coordinator – UGC –SAP-II, Saurashtra University, Rajkot 8. Judge-for Best poster paper presentation award in national and International level conference. 9. Invited talk, Resource person and Session Chairmen at the National and International in various conference in India and Abroad. 10. Nominated as a Chair men for Selection of Vice Chancellor.

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11. Peer reviewer of various National and International Scientific Journals. 12. Member of Editorial Board, in various National and International journals and peer reviewer books published by various publishers. 13. Visited various countries.

Dr. V.H. shah

1. Member and advisor for various selection committees in various University and National Bodies. 2. Judge-for Best poster paper presentation award in national and International level conference. 3. Invited talk, Resource person and Session Chairmen at the National and International in various conference in India and Abroad. 4. Fellow of Indian Chemical Society.

Dr. H.S. Joshi

1. Member and advisor for various selection committees in various University and National Bodies. 2. Nominated as an expert in the field of Analytical Chemistry. 3. Member –Board of Studies, Saurashtra University, Rajkot 4. Co-coordinator – UGC –SAP-II, Coordinator- DSA-I , Saurashtra University, Rajkot 5. Judge-for Best poster paper presentation award in national and International level conference. 6. Invited talk, Resource person and Session Chairmen at the National and International in various conference in India and Abroad. 7. Peer reviewer of various National and International Scientific Journals. 8. Member of Editorial Board, in various National and International journals and peer reviewer books published by various publishers. 9. Visited various countries. 10. Fellow of Indian Chemical Society.

Dr. S.H. Baluja

1. Member and advisor for various selection committees in various University and National Bodies. 2. Nominated as an expert in the field of Physical Chemistry. 3. Co-coordinator – UGC – DSA-I , Saurashtra University, Rajkot 4. Judge-for Best poster paper presentation award in national and International level conference. 5. Invited talk, Resource person and Session Chairmen at the National and International in various conference in India and Abroad. 6. Peer reviewer of various National and International Scientific Journals.

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7. Member of Editorial Board, in various National and International journals and peer reviewer books published by various publishers. 8. Visited various countries. 9. Fellow of Indian Chemical Society.

Dr. U.C. Bhoya

Nominated as an Expert in liquid crystal.

Dr. M.K. Shah

1. Nominated as an expert in the field of Inorganic Chemistry. 2. Judge-for Best poster paper presentation award in national and International level conference. 3. Invited talk, Resource person and Session Chairmen at the National and International in various conference in India and Abroad. 4. Peer reviewer of various National and International Scientific Journals. 5. Member of Editorial Board, in various National and International journals and peer reviewer books published by various publishers. 6. Rector, P.G. Hostel, Saurashtra University. 7. Member of CCDC, Saurashtra University, Rajkot. 8. Co-ordinator, NET coaching and various competitive examinations.

Dr.Y.T. Naliapara

1. Nominated as an expert in the field of Organic Chemistry. 2. Peer reviewer of various National and International Scientific Journals.

Dr. R. C. Khunt

1. Nominated as an expert in the field of Organic Chemistry. 2. Judge-for Best poster paper presentation award in national and International level conference. 3. Invited talk, Resource person and Session Chairmen at the National and International in various conferences in India and Abroad. 4. Peer reviewer of various National and International Scientific Journals. 5. Member of Editorial Board, in various National and International journals and peer reviewer books published by various publishers. 6. Centre Co-ordinator, NET coaching and various competitive examinations. 7. Visited various countries

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Sources of funding for Teaching and Research

1. DST FIST Level II 2011-2015 (Rs 62,00000/-) 2. UGC-SAP DRS II 2009-2014 (Rs 74,50,000/-) 3. UGC-DSA-I ,2015-2020(Rs.1,80,00000) 4. OSDD -2010-2012 (10,00000) 5. Natinal Facility for Drug Discovery 2007 (55000000) 6. DST-DPRP- 71,00000 7. NIH-USA (1,88,0000) 8. IC, Government of Gujarat (65,00000) 9. Center of Excellence-2014- (13,28400000) 10. BSR and Other fellowship (70,00000)

List of Patents

1. Details of patents and income generated: I. Process for Preparation of Pharmaceutically Active N-phenyl (Anthranilic acid) by Ullmann Method." Narsinh Dodia and Anamik Shah. Filing No. & Date: 979/MUM/2000 (02-11-2000)

II. A Process for the Preparation of Methyl substituted dioxatetracyclo Heptadeca-2, 4,6,11,13,15-hexaene." Narsinh Dodia, Rajesh Raval, V. M. Thakor and Anamik Shah. Filing No. & Date: 305/MUM/2001 (30-03-2001)

III. Novel Compound namely methyl substituted Dioxa-tetracyclo Heptadeca-2, 4,6,11,13,15-hexaene." Narsinh Dodia and Anamik Shah. Filing No. & Date: 306/MUM/2001 (30-03-2001) and granted on 30/11/2007

IV. Novel Coumarin compounds as antiviral agents and process of preparations thereof." Dinesh Manvar, Jignesh Patel and Anamik Shah. Indian Provisional Patent Applications No. 584/MUM/2007

V. 6-Methyl-4-phenyl-5-(phenyl or cycloalkyl)carbamoyl-1,2,3,4-tetrahydro pyrimidin-2-one derivatives as Antitubercular Agents." Dhiman Sarkar, Sampa Sarkar, Rohit Joshi, Vijay Khedkar, Raghuvir Pissurlenkar, Evans Coutinho, Anamik Shah. Applications No.: PCT/IB2011/001184 (31.05.2011) / Publication no.: WO2011/151701 (08.12.2011)

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Research grant received from different funding agencies DEPARTMENT OF CHEMISTRY MAJOR RESEARCH PROJECTS Sr. Title of the project Funding Amt. Duration PI No Agency Rs., Lakhs 1. Synthesis of novel hetero-cyclic Dabur 4.5 2002-2005 Dr. A. K. entities Research Shah Foundation 2. Struture Based Drug design, 66.8 2003-2005 Dr. A. K. Synthesis SAR Studies & DST Shah Screening for Novel New Delhi Antitubercular,Ant-ibacterial and Anti-fungal Comp- ounds(WithAlembic Ltd. Vadodara) 4. Bioactive Pyridine UGC, 6.66 2007- Dr. V. H. &Pyrimidines as Anti HIV & New Delhi 2010 Shah Anti-Tumor Agents 5. Process development for some Claris Life 77.24 2008-2010 Dr. A. K. chiral derivatives into non-chiral Sciences, SU, Shah keto acid salts and other DST, compounds useful as New Delhi. pharmaceutical substances. 6. Development of Novel Polyester UGC, 6.81 2008-2011 Dr. P. H. Polyols Based Polyurethane New Delhi Parsania Resins for Bio-composites & Coating Materials 8. Design, Synthesis and DST, 18.84 2008-2011 Dr. R. C. Characterization of some new New Delhi Khunt Heterocycles as an Antituberculor agents 10. Synthesis of Anticancer activity SU 0.50 2009-2012 Dr. M. K. of metal pyridodipyrimidines Shah 11. Novel metal porphyrins as UGC, 1.4 2010-2012 Dr. M. K. photodynamic therapeutics New Delhi Shah 12. Use of Renewable Resources DST, 20.00 2010-2013 Dr. P. H. and Novel Epoxy Resins for New Delhi Parsania Value Added Natural Fiber Reinforced Plastics 13. Development of deuterium BRNS, 20.00 2010-2013 Dr. A. K. labeled pharmaceutically active New Delhi Shah

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compounds suitable for use in pharmaceutical research 14. Design, synthesis and CSIR, 15.00 2010- Dr. V. H. Bioevaluation of pyridines and New Delhi 2013 Shah Pyrimidines as potential Antituberculor Agents 15. Synthesis of Specialty CSIR, 13.23 2011-2014 Dr. P. H. Bisphenol-C-Epoxy , Bisphenol- New Delhi Parsania C-Novolac and Their Vinyl Ester Resins for Value Added Fiber Reinforced Composites and CoatingMaterials

16. Development of efficient P- DBT, 46.82 2011-2013 Dr. A. K. glycoprotein Inhibitors based on New Delhi Shah Structure Based Drug Design (SBDD) and In-silico Comparative Studies 17. Synthesis and Study of Liquid SU 0.50 2011-2013 Dr. U. C. crystalline Materials Bhoya 18. Syntheiss and anticancer activity UGC, 14.00 2012-2015 Dr. A. K. of new chemical entities (NCE's) New Delhi Shah aromatase inhibitors 19. Design, synthesis and biological UGC, 9.00 2012- Dr. V. H. evaluation ofpyridine and New Delhi 2015 Shah Pyrimidine based heterocyclesaspotential anti - HIV and anti-tumor agents 20. Synthesis and Biological studies UGC, 12.4 2012-2015 Dr. Y. T. on novel aniline nitrogen New Delhi Naliapara mustard containing various heterocycles as potent anticancer agents 21. Synthsis of Rhodium catalysts SU 0.40 2012-2014 Dr. Y. T. Naliapara 22. Design, Synthesis and SU 0.40 2012-2014 Dr. R. C. Characterization of some new Khunt Heterocycles as an anti HIV agents 23. Synthesis and Performance UGC, 8.1 2013-2016 Dr. P. H. Evaluation of Modified New Delhi Parsania Multifunctional Resins and Their Fiber Reinforced Composites

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Based on Renewable Resources 24. Investigation of Pyrazines and UGC, 4.85 2009- Dr. H. S. other heterocyles as New Delhi 2012 Joshi Antituberculor and anti- inflammatory agents 25. A new drug target for diabetes: CSIR, 21 2014- Dr. H. S. Design, synthesis and biological New Delhi 2017 Joshi evaluation of aryl propanoic acid derivatives and thiazolidinediones and their analogs as GPR40 agonist

List of MOU

With Institute 1. NIAID: National Institute of Allergy and Infectious Disease

Non-Clinical Evaluation Agreement 2. CSIR: Central Drug Research Institute Open source for drug discovery 3. European Union: Associate Partner: ERASMUS MUNDUS

With University: 1. Technische University, Vienna 2. R. K. University With Industry 1. Nicolas Piramal Mumbai 2. Claris Life Sciences

Post Doctoral Fellow: 14 NET and GEAT Fellows:64

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Citation and h-index of faculty members Citations in Documents in Total Total Name of Faculty the last 5 h-index the last 5 years Documents Citation years

Dr. P.H. Parsania 55 204 932 950 14

Dr. A.K. Shah 54 157 1517 1645 22

Dr. V. H. Shah 11 204 446 595 13

Dr. H.S. Joshi 61 130 750 800 16

Dr.S.H. Baluja 69 179 600 850 14

DrU.C. Bhoya 30 35 56 70 4

Dr. M.K. Shah 13 18 41 85 4

Dr. Y.T. Naliapara 32 23 350 455 8

Dr. R.C. Khunt 30 70 32 235 10

Total 345 1020 4724 5685 105

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Publications in Major Journals:

Sr. Name of Journal( No. of Publication in same Impact ISSN ISSN No. journal) Factor (online) (Print) 5.115 0022-2623 1 Journal of Medicinal Chemistry (1) 1520-4804

4.274 1873-5592 2 Current Drug Targets (1) 1389-4501

3.825 3 British Journal of Pharmacology, UK (1) 1476-5381

2.624 0960- 4 Bioorganic & Medicinal Chemistry letters (6) 894X 2.522 5 European Journal of Pharmacology (1) 0014-2999

2.511 6 Journal of Molecular Catalysis: A Chemical (1) 1381-1169

2.509 7 Tetrahedron Letters (3) 0040-4039

2.221 8 International journal of Antimicrobial Agent (1) 0924-8579

2.187 9 European Journal of Medicinal Chemistry (5) 0223-5234

2.174 10 Polymer Degradation and Stability(2) 0141-3910

2.113 11 European Polymer Journal(1) 0014-3057

1.897 12 Z. Kristallograhy (1)

1.730 13 Medicinal Chemistry Research(1) 1554-8120 1054-2523

1.680 14 Fluid Phase Equilibria(3) 0378-3812

1.589 15 Analytical Sciences, Japan (10) 1348-2246 0910-6340

1.510 16 Structural Chemistry (1) 1572-9001 1040-0400

1.479 17 Anticancer Research (6) 1791-7530 0250-7005

1.438 18 Chromatographia (1) 1612-1112 0009-5893

1.417 19 Thermochim. Acta (1) 0040-6031

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1.306 20 Journal of Applied Polymer Science(4) 1097-4628

1.273 21 In vivo (2) 1791-7549 0258-851X

1.233 22 App. Organomet. Chem. (1) 1099-0739

1.106 23 J. Mol. Liq. (1) 0167-7322

1.030 24 The Journal of AOAC international (1)

0.863 25 Crystal Research and Technology (2) 1521-4079

0.800 26 Journal of Macromolecular Science Part:A (1) 1520-5738 1060-1325

0.772 27 Spectroscopic Letter (1)

0.743 28 Phys. Chem. Liq. (2) 1029-0451 0031-9104

0.737 29 Current Science (2) 0011-3891

0.712 30 Chin. J. Chem. (1) 1614-7065

0.658 31 Journal of Chemical Crystallography (3) 1572-8854 1074-1542

0.646 32 Turkish J. Biol. (1) 1303-6092 1300-0152

0.644 33 J. Iran. Chem. Soc., (1) 1735-2428 1735-207X

0.63 34 ARKIVOC (6) 1551-7012 1551-7004

0.596 35 Arzneimittle-Forsch/ Drug Research (2) 0004-4172

0.567 36 Acta Crystallographica-E (15) 2056-9890

0.561 37 Acta Phys. Chim. (1 ) 1872-1508

0.520 38 Phosphorus, Sulphur, Silicon and Related Elements (3) 1563-5325 1042-6507

0.491 39 Indian Journal of Chemistry-B (5) 0975-0983 0376-4699

0.478 40 Molecular Crystal Liquid Crystal (3) 1563-5287 1542-1406

0.473 41 Heterocyclic Communications (3) 2191-0197

Indian Journal of Chemistry, Section B: Organic 42 0.456 0915-0983 0376-4699 Chemistry Including Medicinal Chemistry (6)

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0.452 43 Journal of the Serbian Chemical Society(4) 0352-5139

0.427 44 Journal Reinforced Plastics and Composites 0731-6844

0.423 45 Journal of Serbian Chemical Society (2)

Phosphorous, Sulfur and Silicon and the Related 46 0.394 1563-5325 1042-6507 Elements (2) 0.374 47 Russ. J. Gen. Chem. (1) 1608-3350 1070-3632

0.357 48 Journal of the Indian Chemical Society (10) 0019-4522

0.340 49 Journal of Indian Chemical Society(5)

0.333 50 Polymer Plastics Technology and Engineering (8) 0360-2559 1525-6111

0.292 51 Journal of Polymer Materials (9) 0973-8622 0970-0838

0.254 52 Indian Journal of Heterocyclic Chemistry (10) 0971-1627

0.210 53 Journal of Chemical Research (1) 1747-5198

0.209 54 Iran. J. Chem. Chem. Eng. (1) 1021-9986

0.178 55 Journal of Scientific and Industrial Research (4) 0022-4456 0975-1084

56 Journal of Engineering and Material Science (1) 0971-4588 0975-1017

57 Organic Chemistry: An Indian Journal (3) 0974-7516

0250- 58 Indian Journal of Pharmaceutical Sciences (2) 1998-3743 474X

59 Journal of Pure and Applied Ultrasonic (1) 0256-4637

60 Journal of Sciences, Islamic Republic of Iran (3) 1016-1104

61 Journal of the Institution of Chemists (India)(3) 0020-3254

0250- 62 Indian Journal of Pharmaceutical Sciences (1) 1998-3743 474X 63 Journal of Chemical Enjeneering data(1) 1.75 0021-9568 64 Russian J. Of Physical Chemistry 0.42 0036-0244 1531-863X

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5. Brief write up about the THRUST areas of Research: A good quantum of the work has been carried out and is going on in the thrust areas mentioned in Sr. No.2. Promising results have been achieved especially in the field of synthetic Organic, Medicinal and Polymer Chemistry (especially natural fiber reinforced composites). Similarly a considerable work has been done in the field of ultrasonics and method validation. Liquid crystal and nanomaterials are emerging areas in the Department. Establishment of new laboratory for pilot scale production of the newly synthesized compounds is in progress. PART B

1) Existing body of research work in that area: The Department of Chemistry has carried out considerable research work in different thrust areas like Synthetic and Medicinal Chemistry, Synthetic Polymers Catalysis, Analytical Chemistry and Liquid crystals

2) How Convincing is the rationale/ significance / expected contribution of the project: The Department has synthesized thousands of compounds for their potential applications and biological activities. Some of them are found very active and further work is in progress. Department has utilized various agriculture work in making various valuable composites for various applications keeping in mind Green Chemistry approach. Recently, Department has synthesized numerous new compounds for biological and catalysis purposes, liquid crystals and carried out method development and validation studies of bio active compounds.

3) Credibility (Experience and expertise) of persons involved: Prof. P. H. Parsania has successfully completed DST-FIST Phase – II program. Prof. Anamik Shah has successfully completed UGC-SAP-DRS-II program and currently Prof. H. S. Joshi is looking after the developmental and research program under UGC- DSA-I program. Various faculties have completed and ongoing projects by various funding agencies like UGC, DST, BRNS, CSIR and National and International collaborative projects. Department has number of National and International tie ups. Recently, Government of Gujarat has Honored Department by sanctioning Center of Excellence for Drug Discovery and support for various industry sectors.

4) Definition and significance/ value of research outputs/deliverables – reports / papers, product/patent, software/translation to state/national policy framework. So far as the Department has published more than 1200 research papers in various scientific National and International peer reviewed journals having impact factor ranging from 0.5 to 5.0 and awarded more than 350 Ph.Ds. Department has patented 5 patents.

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5) Clarity of aims, objectives and research questions Department has sophisticated instrumental testing facilities but to strengthen testing facilities for teaching and research more instruments are required:

6) Methodology – innovativeness/originality and soundness/rigour To strengthen sophisticated instrumental facilities following instrumental support required

LC-MS-MS: Rs 175 Lakhs

Scanning election microscope: Rs 75 lakhs,

800 to 900 MHz Multinuclear NMR spectrometer: 250 Lakhs

7) Definition and significance/value of Concrete outcomes Keeping in mind Environmental problems Department is planning to follow Green Chemistry approach to minimize environmental problems, recycling of waste materials, and judicious use of energy resources, to train skilled man power for industries as well as academic.

The Department has awarded more than 350 Ph. D.s and planning to produce more Ph. D.s and also post docs in various thrust areas of research.

The Department has published more than 1200 research papers in various scientific National and International peer reviewed journals and undertaken industry – academic research projects for technology transfer.

8) Inter-disciplinary/multi-disciplinary orientation and multi-institution networking Department has number of National and International collaborations with various academic institutes and industries.

9) Anticipated outcome (s) of the proposal Green Chemistry approach will help in solving environmental problems and energy saving.

Use of nano catalysts will reduce overall synthetic cost, time, energy, etc.

The use of new technology in the research will improve the scientific approach and knowledge of the researchers.

10) Research and Innovation culture creation among affiliated colleges

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The Department is supporting and guiding affiliated colleges to adopt new techniques in the teaching and research.

6. Research plan and activities under post doctoral programme: Now a day liquid crystals find their versatile industrial applications in diverse field of science such as medicine, electronic devices, cosmetics, fashion design, etc. It is proposed to synthesize and characterized new liquid crystals including polymeric materials for PDF work. Efforts will also made to search their industrial possible applications.

Heterocyclic entities are well known for their wide biological importance. They are most widely useful for pharma industries. For PDF work, it is proposed to synthesize new bioactive substances in support of bio-informatics and chem-informatics techniques. The synthesis of bioactive substances will be carried out on the basis of theoretical prediction to save time and economy.

Nanomaterials are most widely useful in each and every field of science and find tremendous applications. For PD F work, it is proposed to synthesize nano materials (Organic and Inorganic) and their characterization by modern techniques. They will be used as catalysis, fillers, etc. The nano materials will also be used for the improvement of physical properties of the composite materials, which have found excellent applications globally in day to day life.

It is right time to save earth environment. To save air, water and soil pollutions the efforts will be made to synthesize and characterize new materials keeping in mind with Green Chemistry approach..

(Dr. P. H. Parsania)

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Annexure: 9 Proposal for Development Of CENTER OF EXCELLENCE FOR NOVEL DRUG DELIVERY TECHNOLOGY

CENTRE OF EXCELLENCE FOR DOSAGE FORM DEVELOPMENT

1) Outcome and focus area of research proposal The objective of the research proposal is formulation, development and characterization of novel drug delivery system of conventional drugs using application of nanosciences to combat the vital diseases of human being like Genetic disorders, Communicable Diseases, infectious diseases etc.

Focus area of research proposal: Nanoscience can be defined as study of phenomenon and manipulation of materials at atomic and molecular scales. ‘Nanomedicine’ is defined as submicron size modules, used for treatment, diagnosis, monitoring, and control of biological system. Nanomedicine is the monitoring, repair, construction and control of human biological systems at the molecular level, using engineered nanodevices and nanostructures. Drugs with narrow therapeutic indexes create a major challenge for pharmaceutical scientists, during their developments. Application of nanotechnology for the delivery of such drugs can significantly overcome this problem.

Pharmaceutical nanotechnology presents revolutionary opportunities to fight against many diseases. It helps in detecting the antigen associated with diseases such as cancer, diabetes mellitus, neurodegenerative diseases, as well as detecting the microorganisms and viruses associated with infections.

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It is expected that in next 10 years market will be flooded with nanotechnologydevised medicine.

Given the novelty of physicochemical characteristics at the nanometer scale, nanomaterials have potential to impact physiological interactions from the molecular level to the systemic level, making the in vivov administration of nanomedicines an interesting. The rapid development and production of nanomaterials for use as nanomedicines indicate the demand and wisdom for regulating the manufacture and use of nanomaterials. Robust techniques for characterization of nanomaterials are fundamental to regulatory guidelines for ensuring safety of nanomaterials in general and nanomedicines in particular.

Focus area of the department are as follows: Chemical Synthesis, Drug Discovery and Design: Discovery and development of new chemical entities from synthetic and natural product sources as potential drugs; new methods of chemical synthesis and structural elucidation. Neuropharmacology & Neurodegeneration: Innovative research directed at mechanisms of neuronal function under normal conditions and in neurodegenerative diseases such as Alzheimer's disease. Studies range from receptor function, calcium mobilization, cholesterol homeostasis and discovering new drug targets for treating neurodegenerative diseases. Molecular-Cellular Pharmacology and Toxicology is also another focus area of the department.

Isolation of phytoconstituents, standardization of herbal drugs and evaluation of biological activity of medicinal plants: Pharmacognosy deals with scientific study of crude drugs from plants, animals, microbes and

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minerals. It includes quality control, standardization, isolation & characterization of phytoconstituents and formulation development. Apart from classical Pharmacognosy the division is now diversifying itself in the frontier areas of phytomedicine.

Study of the design of Pharmaceutical dosage forms: Drug Delivery, Pharmaceutical Processing and Material Science focuses on the novel applications of pharmaceutical excipients to target drugs to specific sites in the body; to solve problems related to solubility, stability, dissolution rate and bioavailability; and to utilize advanced processing technologies to design innovative drug delivery systems. Design and application of new systems for optimizing drug delivery to specific organs or other biological targets

Bio analytical and Physical Chemistry: Investigation of chemical, biochemical and biomedical questions using a broad range of computational and experimental tools including state-of-the-art instrumentation, synthetic methods and molecular techniques.

Pharmaceutical biotechnology: Pharmaceutical Biotechnology is an increasingly important area of science and technology, and contributes to design and delivery of new therapeutic drugs, the development of diagnostic agents for medical tests, and the beginnings of gene therapy for correcting the medical symptoms of hereditary diseases. Apart from other areas are DNA based vaccine delivery systems, RNAi based therapeutics for gene silencing: siRNA/shRNA design, formulation development, in- vitro, ex-vivo and in vivo evaluation (delivery). Screening, isolation, characterization and scale-up of microbial products (enzymes, antibiotics and other secondary metabolites) from microorganisms of commercial interest and its pharmacological evaluation. Microbial synthesis of nanoparticles:

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Biosynthesis, isolation and characterization, Understanding signalling pathways in cancer pathogenesis and therapy, Gene expression studies.

General outcome of the research areas of the department 1) Prepare pharmacy graduates with the attitudes, knowledge, skills, and abilities, to become highly qualified pharmacists.  Communicate verbally and in writing with patients, caregivers and other health care practitioners.

 Participate in drug-use decision-making process assisting patients and health care professionals in the establishment of therapeutic and diagnostic outcomes.

 Provide high quality pharmaceutical care utilizing ethical and moral standards.

2) Produce pharmaceutical scientists, who through teaching, research and service, contribute to the body of pharmaceutical knowledge.  Provide pharmaceutical education at both undergraduate and graduate levels.

 Publish research findings in refereed indexed national and international scientific periodicals.

 Articulate, communicate and present research findings at local, national and international scientific meetings.

3) Promote pharmaceutical research and knowledge generation through the acquisition of extramural funding and published research data. 4) Build and nurture an environment, which satisfies work, career opportunities and professional growth for faculty, and staff. 5) Provide programs, resources, and services to our patients and the

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community.

2) Scalability and sustainability of project proposed

The main research area of the department is formulation and development of conventional and novel dosage forms of the selected drugs for the treatment of various Genetic disorders, Communicable Diseases, infectious diseases etc.

For scalability, the dosage form must be developed from R & D lab to production department of pharmaceutical companies.

Research and Development level and pilot plant level required all the instruments/equipment for the formulation and analytical development of novel dosage forms like nanoparticles, niosomes, liposomes etc. are available in the department:

Equipments available in the department: Name of Dosage form Capacity Equipment’s developed Tablet compression Conventional, 10 stations machine Sustained release, Rapid mixture controlled release 2 kg. granulator tablets Oscillating granulator 1 kg. Planetary Mixer 2 kg. Sigma blade Mixer 3 kg. Spray Dryer 5 lit. Tray Dryer 12 trays

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Coating Machine 2 kg. Blenders 5 lit. Capsule filling Capsules 100 no. machines Solution preparation liquid dosage forms 5 lit. tank Filtration assembly 3 lit. Rotary bottle washer 10 no. Filling machine 5 no. Capper 10 no. Colloid mill Semisolids dosage 1 kg. Tube filling machine forms 10 no. High speed Nano-based 10 ml. homogenizer formulations Rotary Vacuum 20 ml. evaporator Freeze dryer 100 vials Ultra centrifuge 20 ml. microscope

Once dosage form will be developed by the department up to pilot plant scale, further scale up will be done by the Pharmaceutical industries, whom department has already MOUs.

Name of Pharma. Companies with MOUs of the department:

• Genetic Centre, Ahmedabad

• Vasu Pharmaceuticals, Vadodara

• Espee Pharmaceuticals, Rajkot

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• BAN Laboratories

• Lincoln Pharma Pvt. Ltd.,

• Sehat Pharma Pvt. Ltd.

• Purple Remedies Pvt. Ltd.

 Despite many advances in biomedical research and healthcare technologies, the healthcare burden is increasing globally.

 Huge challenges in healthcare exist and over the next few decades they are set to increase as the population globally ages; and diseases of the developing world become more prevalent in the developed world owing to climate change and, vice versa, owing to increasing urbanization.

 For sustainable health in the future, providing new therapies and treatment strategies, there will have to be changes in the current operating models not only for the pharmaceutical industry but also for academics, regulatory agencies, funders and the public.

 There are several reasons for the increases in healthcare burden.

 All type of the genetic disorders, Communicable Diseases, infectious diseases etc. are increasing day by day in the Gujarat as well as India.

 So, any dosage form developed by the department to cure such disease, definitely it will create the huge change in the existing medicines and improve the life of human beings, as they must sustain for longer period of time.

 India is one of the most strategic regions for the pharmaceutical market. Therefore many multinational giants have been keen to

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invest and grow preferentially in this sector. Developments in the new and advanced techniques in the field of NDDS will create huge demand for variety of excipients usage and development.

 Majority of the pharmaceutical companies in the country have been applying and receiving new patents in the field of the Novel drug delivery systems. This eventually, in the near future derives huge demand for the products and services offered by pharmaceutical and allied businesses.

 Nanotechnology offers various modern applications in novel drug delivery systems that potentially improve the diagnosis, treatment and help monitoring of post-administration transformation of drug composition within the body systems.

 Another important milestone to be mentioned here is Computer aided Drug Design, which offers a lot of scope for the development of this kind of novel and advanced systems.

 Computer aided Drug Design helps in designing and developing the drugs and delivery systems consuming less time and resources with more accuracy and quality compared to traditional methods.

3) Prioritization on area of research done by the state and why

The Department of Science & Technology, Government of Gujarat has identified Nano Science and Nano technology as a fast developing and emerging field where in lie vast opportunities for development of business and industries in Gujarat.

The DST, Govt of Gujarat is proposed to constitute Gujarat Nano Mission which will be responsible for designing and developing Nanoscience and

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nanotechnology education, research and development in the state and to keep pace with national and global streams of development.

The Gujarat Nano Mission is facilitate necessary support and environment to Nanoscience education, research, development, design and engineering in nanotechnology, and transfer the technology to industrial sector in order to increase Gujarat's competitiveness, and improve the quality of life and the environment.

The DST, Govt of Gujarat, is committed to make use of the Nano science and Nanotechnology for the welfare of the society and betterment of the environment. GUJCOST, in the year 2008, has taken the initiative to promote this interdisciplinary field of Nano Science and Nanotechnology which has capable of opening limitless possibilities to create novel things. In this direction, they have six Center of Excellence at SP University, Vallabh Vidyanagar, Gujarat University, Ahmedabad, Bhavnagar University, Bhavnagar, MS University; Baroda, Saurashtra University, Rajkot and Dharmsinh Desai University, .

In the area of health, in addition to health care and targeted drug delivery systems, longer lasting Medical Implants is attractive area where Gujarat can make a mark. These could be made of nanostructured metals and alloys, nanostructured ceramics and composites etc.

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4) Quality of the institution and faculty undertaking research

NAAC – A grade

Sr Name of National Given/Organized Purpose No. of No. of No Faculty Recognition by Publications/Books/B Projects . ook Chapters completed/

ongoing

1 Dr. BHARTIYA The Economic for Excellence in Publications: 154 Total 5 Navin R. SHIKSHA Health and chosen field of projects worth Sheth RATAN Educational activity on the Books: 3; Book 92.5 lacs th Chapters: 1; AWARD growth occasion of 29 Provisional Patents National Filed: 10 Seminar during th 24 August 2009

Dr. P.D. Anchrom For Best Shethi Annual Enterprises Pvt. Research Paper Award-2011 Ltd., Mumbai

Thanks Badge Gujarat State Development of Bharat Scout and Scout-guide Guides activities in Gujarat

2. Dr. Mihir Dr. P.D. Anchrom For Best 41 publications and 39 Total 4 Raval Shethi Annual Enterprises Pvt. Research Paper presentations; projects worth Award-2011 Ltd., Mumbai 77.29 lacs Book Chapter: 1

University Saurashtra Seed Money Young University, Rajkot Project to do teacher Award Research

th Paper 14 International For Scientific selected for workshop on Presentation of poster Physical research presentation characterization of Pharmaceutical solids, Barcelona, Spain.

3. Dr. Gufic Prize Smt. Kishoritai For Research 22 publications Total 2 Sachin Bhoyar College of work in Annual projects worth Parmar Pharmacy Conference on 12 lacs

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Indian Pharmacologica l Society during th th 5 to 7 Jan., 2013

University Saurashtra Seed Money Young University, Rajkot Project to do teacher Award Research

Selected IPS national level Research Paper among Top 10 and International recognition research Symposium, papers for G. Nagpur Achari prize session

4. Dr. Gandhian Society for For Research 27 publications and 39 -- Nirav Young Research and during March presentations; Patel Technological Initiatives for 2014, in IIM, Innovation Sustainable Ahmedabad Book: 01 Award 2014 Technology and

Institutions (SRISTI)

DST INSPIRE DST, New Delhi Research Faculty Award 2013

Best Poster ICONSEA, 2014, International Presentation JNTU, New Delhi Conference on Nano Science & Engineering Applications (ICONSEA- 2014) during26th, 27th & 28th June 2014

5. Dr. DST INSPIRE DST, New Delhi Research 38 publications; Total 1 project Vaibhav Faculty Award worth 16 lacs Bhatt 2013 Book: 02

6. Dr. ------14 Publications -- Nasir Vadia

7. Ms. Dr. S.C. Indian Best paper in 15 publications -- Payal Verma Pharmacological oral Scientific Booksr:02 Bhalodi Memorial Society, Session during

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th a Prize Ahmedabad 16 March 2008

8. Mr. ------08 Publications; -- Kashya p 01 Book Thumm ar

9. Ms.Priy ------05 Publications; -- a Patel 02 Book Chapters

10. Mr. University Saurashtra Seed Money 05 Publications -- Devendr Young University, Rajkot Project to do a teacher Award Research - Vaisnav 2012

st 11. Ms. 1 Prize Nirma Institute of Best paper in 04 Publications -- Hina Pharmacy Poster Scientific Bagada International Session Conference, January 23-25, 2014

st 12. Krishna 1 Prize DST sponsored Best paper in 05 Publications -- Koradiy Two days Poster Scientific a National Seminar Session at Shankersinh Vaghela Bapu institute of Pharmacy in 22 & 23 August 2013

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5) Accountability of the project:

Sr Name of Activity of research Responsibility of the faculty No. Faculty project 1 Dr. Navin Literature review about Most prevalent diseases, their Sheth the utmost diseases of available drugs and dosage the state forms, patents, innovators etc. 2 Dr. Mihir Selection of suitable Physical and chemical properties Raval drugs based on of drugs, preformulation studies physicochemical and remedies to improve its properties and material physicochemical properties and characterization material characterization using various techniques 3 Dr. Sachin Preclinical studies of Animal study Parmar selected drugs 4 Dr. Nirav Dosage form Formulation and optimization of Patel development using dosage form by QbD approach, & Dr. application of Stability study, Scale up, Vaibhav nanotechnology and Technology transfer Bhatt biotechnology 5 Dr. Nasir Analytical method UV. HPLC, LC-MS Vadia development 6 Ms. Payal Bioequivalence study Pharmacokinetic studies Bhalodiya 7 Mr. Regulatory filling Dossier preparation, submission Kashyap Thummar

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6) Phases/implementation milestones and plan action for 2015-16 and 2016-17

Research Project management plan Tasks 1) Review of literature for the diseases like diabetes, hyper tension, Infectious disease, Communicable Diseases, Malnutrition and drugs used to cure the same

2) Procurement of selected drugs and preformulation studies of the drugs and material charecterization

3) Selection of drugs for the dosage form development based on physicochemical properties and status of Innovator product and patents

4) Remedies to improve the overall physicochemical and biopharmaceutical properties

5) Preclinical studies of improved drugs

6) Bio analytical method development of selected drugs

7) Formulation and optimization of novel dosage form by QbD approach

8) Pharmacokinetic study of optimized dosage form

9) Stability study and Scale up of optimized dosage forms

10) Technology transfer of optimized dosage forms

11) Regulatory filling of the prepared dosage form

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Phases/implementation milestones and plan

Task Qtr. 1 Qtr. 2 Qtr. 3 Qtr. 4 Qtr. 1 Qtr. 2 Qtr. 3 Qtr. 4 (2015- (2015- (2015- (2015- (2016- (2016- (2016- (2016- 16) 16) 16) 17) 17) 17) 17) 16) 1 2 3 4 5 6 7 8 9 10 11

7) Financial resources, financial plan and financial sustainability

Phases/implementation milestones and plan Task Planned budget (INR) 2 10,00,000 3 2,00,000 4 2,20,000 5 10,00,000 6 15,00,000 7 20,00,000 8 15,00,000 9 10,00,000 10 23,00,000 11 20,00,000 Total 1,27,20,000/-

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8) Quality improvement/gap filling projection The up gradation of the laboratories of the department with equipment facilities and infrastructure will be required.  List of Equipments required with approximate budget

Sr. Name of the Major instruments Amount in Rs. No. 1 TEM 1200000 2 XRD 1800000 4 NexION® 350 ICP-MS Spectrometers 1400000 5 Multi-Angle Light Scattering Detector for 600000 UHPLC 6 Precision Powder Mixing appratus 200000 7 Particle Surface Area and size Analyzer with Sample Circulation (Multi-faceted 1000000 Nanoparticle Analyzer) 8 Rheometer 800000 9 Hot Stage Microscope 2100000 10 Table top NMR 2000000 11 Raman Spectro Photometer and Microscope 3000000 12 Cascade Impactor 1500000 13 Inhalation Test Equipment 1000000 15 Cryostat 700000 16 NanoQuant Spectrophotometer 1300000 17 Real Time PCR Machine 800000 18 Biosafety Cabinet (Class II) 500000 19 Bio-analyzer System 500000 20 Capillary Electrophoresis 600000 23 Spectroflourimeter 600000 24 Chemi Doc System 800000 Total (A) Rs. 2,24,00,000/-

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Total budget

Sr Particluars Amount No. (INR) 1 For the execution of research plan 1,27,20,000/- 2 Equipments 2,24,00,000/- 3 Contigency, Travel, Overhaed, TA/DA of research 44,00,000/- fellow, Fellowship of Ph.D/Post doct fellows, etc. 4 Remuneration of Qulaified Research asstistant 4,80,000/- (20,000 pm) (Two Years) Total 4,00,00,000/-

User Departments: (i) Department of Pharmaceutical Sciences (ii) Department of Chemistry (iii) Department of Biochemistry

Requirement of Project: Project Fellow: 18 (Experimental, Computational and Theoretical) RA: 06 (Experimental, Computational and Theoretical) Instrument oprators/care taker: 02 persons (20,000 rs. Per person per month) Arrangement of Symposia/Seminars/Workshops/Conferences: 10 Lakh Approx. Facility Will be utilized by faculties: 13, students: 100 PG and 17 Ph.D

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9) Evidence/plan of academic-industry partnership

Novel drug delivery systems of conventional drugs will be developed by department and then its scale up, technology transfer and approval form various regulatory agencises will be carried out in collobration with Phaarmaceutical industry.

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PART B

Existing body of research work in that area - (fresh proposals not allowed). Fit and credibility of past work, Past achievements of proposed centre/concerned research team

About the Department with its past Achievements  Established on 17/10/2006  AICTE, PCI-New Delhi and UGC-SAP approved first PG department in entire Saurashtra region  Impart M. Pharm in 1. Herbal Drug Technology, 2. Pharmaceutics, 3. Pharmaceutical biotechnology 4. Pharmacology 5. QA 6. RA 7. Master in Pharmacy Management (MPM) Started in academic year 2014-15.  Also imparts PGDCR, Certificate course in dialysis technique  PhD

International collaboration  University Of New Mexico, New Mexico: Dr. Sachin Parmar underwent 2 Months Training Program at New Mexico b) National collaboration  The Gujarat Ayurveda University (GAU), Jamnagar Two Projects were done in collaboration with GAU on epilepsy and diabetes. Projects were completely sponsored by Gujarat Ayurveda University and additionally students were given Rs. 5000/- as scholarship.  BAN laboratories Pvt. Ltd.: Project was done to evaluate hepatotoxicity of BAN products. Products were sponsored by BAN Labs. Project of hair growth promoting products is to be done for pharmacognostic and pharmacology activity of BAN products: Rs. 2,00,000/-.

International Recognition: Collaboration with various centres • University of New Mexico, USA

• The University of Winchester, UK

• University of Central Lancashire, UK

National Recognition: Collaboration with various centres • IIIM, Jammu

• Gujarat Ayurveda University, Jamnagar

• CSMCRI, Bhavnagar

State Recognition: Collaboration with various centres • Christ College, Rajkot

• B.T. Savani Kidney hospital, Rajkot

• Wochardt Hospital, Rajkot

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• Genetic Centre, Ahmedabad

• Vasu Pharmaceuticals, Vadodara

• Espee Pharmaceuticals, Rajkot

• BAN Laboratories

• Lincoln Pharma Pvt. Ltd.,

• Sehat Pharma Pvt. Ltd.

• Purple Remedies Pvt. Ltd.

Number of papers published in peer reviewed journals 2009 : 15 2010 : 40 2011 : 33 2012 : 34 2013 : 37 2014: 23 2015: 08  Total Publications: 190  h index : Avg - 7; Highest – 12  Impact Factor: Avg – 0.9; Highest - 5  Paper presented approximately (101 – National, 26-International),  Total no. of patents filed: 10  Total Project sanctioned by various agencies like AICTE, GUJCOST, UGC, DST, ICMR, etc– 15 worth Rs. 03, 02, 74, 000/-  CPCSEA approved animal facility  DCGI approved Human Ethics Committee “ETHICLIN” for BA/BE studies.

Achievements of Research Team

Sr Name of National Given/Organize Purpose No. of No. of No Faculty Recognition d by Publications/Books/Boo Projects . k Chapters completed / ongoing

1 Dr. Navin BHARTIYA The Economic for Excellence in Publications: 154 Total 5 R. Sheth SHIKSHA Health and chosen field of projects RATAN Educational activity on the Books: 3; Book Chapters: worth 92.5 AWARD growth th 1; Provisional Patents lacs occasion of 29 Filed: 10 National Seminar during th 24 August 2009

Dr. P.D. Anchrom For Best Shethi Enterprises Pvt.

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Annual Ltd., Mumbai Research Paper Award-2011

Thanks Gujarat State Development of Badge Bharat Scout and Scout-guide Guides activities in Gujarat

2. Dr. Mihir Dr. P.D. Anchrom For Best 41 publications and 39 Total 4 Raval Shethi Enterprises Pvt. Research Paper presentations; projects Annual Ltd., Mumbai worth Award-2011 Book Chapter: 1 77.29 lacs

University Saurashtra Seed Money Young University, Rajkot Project to do teacher Research Award

th Paper 14 International For Scientific selected for workshop on Presentation of poster Physical research presentation characterization of Pharmaceutical solids, Barcelona, Spain.

3. Dr. Gufic Prize Smt. Kishoritai For Research 22 publications Total 2 Sachin Bhoyar College work in Annual projects Parmar of Pharmacy Conference on worth 12 Indian lacs Pharmacologica l Society during th th 5 to 7 Jan., 2013

University Saurashtra Seed Money Young University, Rajkot Project to do teacher Research Award

Selected IPS national level Research Paper among Top and International recognition 10 research Symposium, papers for G. Nagpur Achari prize session

4. Dr. Nirav Gandhian Society for For Research 27 publications and 39 -- Patel Young Research and during March presentations;

Technologica Initiatives for 2014, in IIM,

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l Innovation Sustainable Ahmedabad Book: 01 Award 2014 Technology and

Institutions (SRISTI)

DST DST, New Delhi Research INSPIRE Faculty Award 2013

Best Poster ICONSEA, 2014, International Presentation JNTU, New Delhi Conference on Nano Science & Engineering Applications (ICONSEA- 2014) during26th, 27th & 28th June 2014

5. Dr. DST DST, New Delhi Research 38 publications; Total 1 Vaibhav INSPIRE project Bhatt Faculty Book: 02 worth 16 Award 2013 lacs

6. Dr. Nasir ------14 Publications -- Vadia

7. Ms. Dr. S.C. Indian Best paper in 15 publications -- Payal Verma Pharmacological oral Scientific Booksr:02 Bhalodia Memorial Society, Session during th Prize Ahmedabad 16 March 2008

8. Mr. ------08 Publications; -- Kashyap Thumma 01 Book r

9. Ms.Priya ------05 Publications; -- Patel 02 Book Chapters

10. Mr. University Saurashtra Seed Money 05 Publications -- Devendra Young University, Rajkot Project to do Vaisnav teacher Research - Award 2012

st 11. Ms. Hina 1 Prize Nirma Institute of Best paper in 04 Publications -- Bagada Pharmacy Poster Scientific International Session Conference, January 23-25,

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2014

st 12. Krishna 1 Prize DST sponsored Best paper in 05 Publications -- Koradiya Two days Poster Scientific National Seminar Session at Shankersinh Vaghela Bapu institute of Pharmacy in 22 & 23 August 2013

Area of Working of Research Team

Sr. Name of the Member Research Area No. 1 Dr. Navin Sheth  Traditional and herbal drug standardization 2 Dr. Mihir Raval  Crystallography, Particle engineering,

 Functionality improvement of API,

 Bioavailability enhancement

3 Dr. Sachin Parmar  Neuropharmacology and Toxicology 4 Dr. Nirav Patel  Nano technology & Targetted Drug Delivery for Cancer Research 5 Dr. Vaibhav Bhatt  Metagenoics, Meta-transciptomics exome sequensing and gene expression 6 Dr. Nasir Vadia  Development and Validation of Analytical Methods 7 Ms. Payal Bhalodiya  Metabolic Disorders, P’covigilance 8 Mr. Kashyap Thummar  Impurity Profiling 9 Ms. Priya Patel  Nano based drug delivery for lung targetting 10 Mr. Devendra Vaishnav  Novel Concepts of Biotechnology like Protein Crystallization, Fermentation Technology, Enzyme technology, SNPs Analysis 11 Ms. Heena Bagda  Bioanalytical Method Development 12 Ms. Krishna Koradia  Nanocrystallization and Solubility/Bioavailability improvement

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Contribution to the field/Publications

Dr. Navin Sheth

1. Gangwal Amit P, Parmar Sachin K, Gupta GL, Rana AC, Sheth Navin R. Immunomodulatory effects of Lagenaria siceraria fruits in rats. Pharmacognosy Magazine. 2008;4(16). 2. Gangwal Amit P, Parmar Sachin K, Mardia Rajnikant B, Sheth Navin R. Immunomodulatory activity of saponin mixture isolated from Lagenaria siceraria fruits. Nigerian Journal of Natural Products and Medicine. 2008;12(1). 3. Katbamna Rachana V, Rana Mehul G, Dhudhrejiya Ashvin V, Sheth Navin R. In vitro antioxidant activity of leaves extracts of Caesalpinia bonducella. Pharmacologyonline. 2008;3:3665-73. 4. Parmar Sachin K, Gangwal Amit P, Mardia Rajnikant B, Dudhregiya Ashvin V, Sheth Navin R, editors. Antihistaminic, anti-inflammatory and mast cell stabilizing activity of ethanolic extract of Solanum xanthocarpum in experimental animal. Indian journal of pharmacology; 2008. 5. Rana Mehul G, Katbamna Rachna V, Dudhrejiya Ashvin V, Sheth Navin R. Hepatoprotection of Tecomella undulata against experimentally induced liver injury in rats. Pharmacologyonline. 2008;3:674-82. 6. Bhalodia Yagnik S, Patel N J, Patel R K, Vaghasiya J D, Jivani N P, Sheth Navin R. Benincasa cerifera ameliorates renal ischemia/reperfusion injury in hyperlipidemic rat. Pharmacognosy Research. 2009;1(6):406. 7. Bhalodia Yagnik S, Sheth Navin R, Vaghasiya Jitendra D, Jivani Nurudin P. Cardiac damage induced by renal ischemia/reperfusion injury in hyperlipidemic rats: Role of PPAR-α agonist. Hong Kong Journal of Nephrology. 2009;11(2):59-65. 8. Bhalodia Yagnik S, Vaghasiya Jitendra D, Malaviya SV, Jivani Nurudin P, Sheth Navin R. Lipid peroxidation and renal injury in renal ischemia/reperfusion: Effect of Benincasa cerifera. International Journal of Green Pharmacy. 2009;3(4):310. 9. Dedania Zarna, Dedania Ronak, Karkhanis Vaishali, Vidya Sagar G , Baldania Meeta, Sheth Navin R. RP-HPLC Method for Simultaneous Estimation of Omeprazole and Ondansetron in combined dosage forms. Asian Journal of Research in Chemistry. 2009;2(2):108-11. 10. Dudhregiya Ashvin V, Shah Rumit M, Sanandiya Jalapa R, Dabhi Mahesh R, Savaliya Vaibhavi B, Sheth Navin R. In vitro antioxidant activity of flowering tops of Ipomoea palmata. Pharmacologyonline. 2009;2:392-401. 11. Gangwal Amit P, Parmar Sachin K, Sheth Navin R. Isolation and immunomodulatory activity of phytoconstituents of Lagenaria siceraria. Pharm Commun. 2009;2:46-50. 12. Malaviya Shailesh, Nandakumar K, Vaghasiya Jitendra D, Bhalodiya Yagnik , Jivani Nurudin P, Sheth Navin R, Manek Ravi, Chauhan Sanjay Anxiolytic activity of root extracts of Cardiospermum halicacabum in mice. International journal of pharmacology. 2009;7:1-6. 13. Parmar Komal R, Patel Kalpesh A, Shah Sunny R, Sheth Navin R. Inclusion complexes of lamotrigine and hydroxy propyl β-cyclodextrin: solid state characterization and dissolution studies. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 2009;65(3-4):263-8. 14. Patel J K, Shah A M, Sheth Navin R. Aqueous-based film coating of tablets: study the effect of critical process parameters. International journal of Pharmatech research. 2009;1(2):235-40. 15. Patel R, Singh SK, Singh S, Sheth Navin R, Gendle R. Development and characterization of curcumin loaded transfersome for transdermal delivery. Journal of Pharmaceutical Sciences and Research. 2009;1(4):71-80. 16. Sanadiya Jalapa R, Parmar Sachin K, Sheth Navin R. Phrmacognostical study of Cymbopogon martinii (Roxb.) watson. Journal of Herbal Medicine and Toxicology. 2009;3(2):99-103.

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17. Sanja SD, Sheth NR, Patel NK, Patel Dhaval, Patel Biraju. Characterization and evaluation of antioxidant activity of Portulaca oleracea. International journal of pharmacy and pharmaceutical sciences. 2009;1(1):74-84. 18. Sanja S D, Sheth Navin R, Joshi D M, Golwala D K, Patel Dhaval, K Raval Mihir. Anti Inflammatory Activity of Ipomoea reniformis Methanolic Extract. International Journal of Pharmaceutical Sciences and Drug Research. 2009;1(3). 19. Singh S K, Singh S, Sheth Navin R, Ushir Yogesh V, Patel R, Singh A. Design, development and evaluation of Domperidone pellets. Int J PharmTec Resch. 2009;1(3):885-91. 20. Singh S K, Ushir Y V, Chidrawar R V, Vadalia K R, Sheth Navin R, Singh S. Preliminary evaluation of Cassia auriculata seed mucilage as binding agent. Pharmacognosy Journal. 2009;1(4):251. 21. Sudarshan S, Sangeeta S, Sheth Navin R, Roshan P, Ushir YV, Gendle R. Colon specific drug delivery system of mesalamine for eradication of ulcerative colitis. Research Journal of Pharmacy and Technology. 2009;2(4):819-23. 22. Vaghasiya Jitendra, Sheth Navin, Bhalodia Yagnik, Jivani Nurudin. Diabetes Type-II Exaggerated Remote Organ Injury Induced by Renal Ischemia Reperfusion. Drug Invention Today. 2009;1(1). 23. Vaghasiya Jitendra D. Exenatide Treatment Protects Exaggerated Remote Organ Injury Induced by Renal Ischemia Reperfusion in Diabetes. Journal of Nephrology and Renal Transplantation. 2009;2(2):55-68. 24. Vaghasiya Jitendra D, Sheth Navin R, Bhalodia Yagnik S, Jivani Nurudin P. Diabetes type-II exaggerates renal ischemia reperfusion injury by elevation of oxidative stress and inflammatory response. Journal of Young Pharmacists. 2009;1(2):151. 25. Bhalodia Yagnik, Sheth Navin, Vaghasiya Jitendra, Jivani Nurudin. Role of fenofibrate alone and in combination with telmisartan on renal ischemia/reperfusion injury. Renal failure. 2010;32(9):1088- 94. 26. Bhalodia Yagnik S, Sheth Navin R, Vaghasiya Jitendra D, Jivani Nurudin P. Hyperlipidemia enhanced oxidative stress and inflammatory response evoked by renal ischemia/reperfusion injury. International journal of pharmacology. 2010;6(1):25-30. 27. Bhatt Punit R, Pandya Kajal B, Sheth Navin R. Camellia sinensis (L): The medicinal beverage: a review. International journal of pharmaceutical sciences review and research. 2010;3(2):3-6. 28. Chauhan Sanjay P, Sheth Navin R, Jivani Nurudin P, Rathod I S, Shah P I. Biological actions of Opuntia species. Systematic Reviews in Pharmacy. 2010;1(2):146. 29. Dabhi Mahesh R, Mathasoliya Ashvin V, Sheth Navin R, Patel Nilesh K, Dudhrejiya Ashvin V. Preparation, characterization and dissolution studies of ß-cyclodextrin inclusion complexes of drotaverine hydrochloride. Inventi Rapid: Pharm Tech. 2010. 30. Dabhi Mahesh R, Nagori Stavan A, Gohel Mukesh C, Parikh Rajesh K, Sheth Navin R. Formulation development of smart gel periodontal drug delivery system for local delivery of chemotherapeutic agents with application of experimental design. Drug delivery. 2010;17(7):520-31. 31. Gangwal A, Parmar SK, Sheth NR. Phytochemical investigation and immunomodulatory activity of Lagenaria siceraria fruits. Journal of Natural Remedies. 2010;10(2):170-4. 32. Gangwal Amit P, Parmar Sachin K, Sheth Navin R. Triterpenoid, flavonoids and sterols from Lagenaria siceraria fruits. Der Pharmacia Lettre. 2010;2(1):307-17. 33. Kalariya Manisha, Parmar Sachin K, Sheth Navin R. Neuropharmacological activity of hydroalcoholic extract of leaves of Colocasia esculenta. Pharmaceutical biology. 2010;48(11):1207-12. 34. Kathad Hina K, Shah R M, Sheth Navin R, Patel K N. In vitro antioxidant activity of leaves of Garuga pinnata Roxb. International Journal of Pharmaceutical Research. 2010;2(3):9-13. 35. Malaviya S V, Manek Ravi A, Vaghasiya Jitendra D, Bhalodia Yagnik S, Sheth Navin R, Jivani Nurudin P. Effect of rutin on oxidative cardiac enzymes in induced myocardial infaraction and left

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ventricular hypertrophy. Inventi Impact: Ethnopharmacology. 2010.

36. Manek RA, Sheth NR, Vaghasiya JD, Malaviya SV, Jivani NP. Evaluation of antibacterial effects of a combination of Adhatoda vasica leaves with Glycyrrhiza glabra roots and rhizome extracts. Inventi Rapid: Ethnopharmacology. 2010. 37. Manek Ravi A, Sheth Navin R, Vaghasiya Jitendra D, Malaviya S V, Jivani Nurudin P. Synergistic interaction of Glycyrrhiza glabra roots extract on antimicrobial activity of Solanum xanthocarpum herb extract. Inventi Impact: Molecular Pharmacology. 2010. 38. Parmar Sachin, Gangwal Amit, Sheth Navin. Mast cell membrane stabilization and antihistaminic actions: possible mechanism of action of anti-inflammatory action of Murraya koenigii. Journal of Current Pharmaceutical Research. 2010;2(1):21-5. 39. Parmar Sachin, Gangwal Amit, Sheth Navin. Solanum xanthocarpum (yellow berried night shade): a review. Der pharmacia lettre. 2010;2(4):373-83. 40. Parmar Sachin K, Gangwal Amit P, Prajapati T R, Pandya K B, Ranpariya Vishvash L, Sheth Navin R. Evaluation of anti-asthmatic activity of ethanolic extract of Solanum xanthocarpum leaves. Pharmacologyonline. 2010;2(1):410-24. 41. Parmar Sachin K, Gangwal Amit P, Sheth Navin R. Evaluation of antiasthmatic activity of a polyherbal formulation containing four plant extracts. Journal of Current Pharmaceutical Research. 2010;2(1):40-4. 42. Patel Dhaval V, Patel Biraju D, Patel Nilesh K, Sheth Navin R, Dabhi Mahesh R, Dudhrejiya Ashvin V. Quality Improvement Methodologies in Pharmaceutical Manufacturing. Asian Journal of Management. 2010;1(1):1-3. 43. Patel Jaydeep D, Dhingani Anjali, Dabhi Mahesh R, Patel Nilesh K, Raval Mihir K, Sheth Navin R. Design and development of sustained release microspheres of Quetiapine Fumarate using 32 full factorial design. Journal of Pharmacy Research. 2010;3(12). 44. Prajapati Rakesh P, Kalariya Manisha, Parmar Sachin K, Sheth Navin R. Phytochemical and pharmacological review of Lagenaria sicereria. Journal of Ayurveda and integrative medicine. 2010;1(4):266. 45. Ramolia Chetan, Dedania Zarna, Dedania Ronak, Sheth Navin R, Patel Bhavna, Bhatt K K. Simultaneous estimation of metformin hydrochloride, rosiglitazone maleate and glimepiride in pharmaceutical dosage forms by RP-HPLC method. Asian Journal of Research in Chemistry. 2010;3(1):83-6. 46. Rana Mehul G, Katbamna Rachana V, Padhya Aashish A, Dudhrejiya Ashvin D, Jivani Nurudin P, Sheth Navin R. In vitro antioxidant and free radical scavenging studies of alcoholic extract of Medicago sativa L. Romanian Journal of Biology - Plant Biology. 2010;55(1):15-22. 47. Rao Priya Shaival, Sheth Navin R, Jayaveera K N, Rao Shaival K. Pharmacognostic standardization of the leaves of Pimenta dioica Linn. International Journal of Pharmaceutical Sciences and Research. 2010;1(9):110-5. 48. Raval MK, Chaudrari K, Shah B, Patel JD, Sheth NR, Parikh RK. Formulation and evaluation of matrix type transdermal drug delivery system containing ondansetron hydrochloride. Inventi Rapid: NDDS. 2010. 49. Raval MK, Prajapati DU, Varma SM, Khodifad MA, Patel JM, Sheth NR. Influence of some hydrophilic polymers on dissolution characteristics of furosemide through solid dispersion: An unsatisfied attempt for immediate release formulation. Journal of Pharmaceutical Negative Results. 2010;1(2):29. 50. Raval Mihir K, Bagda Aarti A, Patel J M, Paun Jalapa S, Chaudhari Karmsinh R, Sheth Navin R. Preparation and Evaluation of Sustained Release Nimesulide Microspheres Using Response Surface Methodology. Journal of Pharmacy Research. 2010;3(3).

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51. Raval Mihir K, SatheshBabu P R, Thimmasetty J, Parikh R k, Sheth Navin R, Subrahmanyam C. Influence of solvents on the crystal habit and properties of rofecoxib and celecoxib: No evidence of polymorphism. Journal of Pharmaceutical Negative Results. 2010;1(2):40-50. 52. Sailor Girish U, Parmar Ghanshyam, Dudhregiya Ashvin V, Sheth Navin R, Sheth A K. Pharmacognostical and Preliminary Phytochemical Investigation of Leucas cephalotes (Roth) Spreng International Journal of Pharmaceutical Research 2010;2(1):14-21. 53. Shah Rumit M, Kathad Heena, Sheth Rajal N, Sheth Navin R. In vitro antioxidant activity of roots of Tephrosia purpurea linn. International Journal of Pharmacy & Pharmaceutical Sciences. 2010;2(3):30-3. 54. Shah V K, Zalavadiya V I, Sheth Navin R, Raval Mihir K, Dudhrejiya Ashvin D, Golwala D K. Standardization and assessment of preformulation parameters of rasayana Tablet. International Journal of Pharmaceutical Sciences and Drug Research. 2010;2(1):58-62. 55. Singh SK, Gendle R, Sheth NR, Roshan P, Singh S. Isolation and evaluation of binding property of Zizyphus jujuba Lamk. seed mucilage in tablet formulations. Journal of Global Pharma Technology. 2010;2(1). 56. Singh S K, Chidrawar V R, Ushir Y V, Vadalia K R, Sheth Navin R, Singh S. Pharmaceutical characterization of amoxicillin trihydrate as mucoadhesive microspheres in management of H. pylori. International journal of pharmtech research. 2010;2:348-58. 57. Soni H K, Ribadiya N C, Bhatt S B, Sheth Navin R. Evaluation of herbal formulation (capsule) containing Ashwagandha as a single herb with their nutritional value determination. International Journal of Applied Biology and Pharmaceutical Technology. 2010;1(3):960-7. 58. Soni Hardik K, Shah Bhavik R, Bhatt Surendra B, Sheth Navin R. Standardization of single herb capsules of Manjistha, Kokam and Punarnava with assessment of their Nutritional value. Journal of Pharmacy Research. 2010;3(8). 59. Sood P P, Rao A P, Joshi K K, Tyagi S, Patel A D, Sheth Navin R, Shah Anamik K. Fluctuations of glycosidases during mercury stress and their renovation with natural and synthetic antioxidants and B vitamins. Journal of Cell & Tissue Research. 2010;10(3). 60. Sood P P, Vijayalakshmi K, Joshi K K, Tyagi S, Sheth Navin R, Shah Anamik K. Biochemical alterations of carbohydrate metabolizing enzymes in mmc stressed mice and ameliorative effect of natural and synthetic antioxidants. Journal of Herbal Medicine and Toxicology. 2010;4(2):25-34. 61. Vaghasiya Jitendra D, Sheth Navin R, Bhalodia Yagnik S, Jivani Nurudin P. Exaggerated liver injury induced by renal ischemia reperfusion in diabetes: effect of exenatide. Saudi journal of gastroenterology. 2010;16(3):174. 62. Vaghasiya Jitendra D , Sheth Navin R , Bhalodia Yagnik S, Jivani Nurudin P. Cardiac complication of renal ischemia/reperfusion in diabetes: Effect of glucagon-like peptide-1 receptor agonist. Inventi Impact: Molecular Pharmacology. 2010;2010(1):1-5. 63. Vaghasiya Jitendra D, Sheth Navin R, Bhalodia Yagnik S, Malaviya Shailesh, Jivani Nurudin P. Exenatide protects renal ischemia reperfusion injury in type 2 diabetes mellitus. International Journal of Diabetes in Developing Countries. 2010;30(4):217. 64. Vinzuda Dhara U, Sailor Girish U, Sheth Navin R. RP-HPLC method for determination of valsartan in tablet dosage form. International Journal of ChemTech Research. 2010;2(3):1461-7. 65. Zalavadiya Vrinda I, Shah Vipul K, Sheth Navin R, Chakraborty Sumit. Pharmacognostical and Preliminary Phytochemical Screening of Erythrina indica Linn. Research Journal of Pharmacognosy and Phytochemistry. 2010;2(3):220-4. 66. Bhalodia Yagnik S, Sheth Navin R, Vaghasiya Jitendra D, Jivani Nurudin P. Homocysteine- dependent endothelial dysfunction induced by renal ischemia/reperfusion injury. Journal of nephrology. 2011;117:000-0.

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67. Chauhan Kinjal, Sheth Navin R, Ranpariya Vishavas L, Parmar Sachin K. Anticonvulsant activity of solasodine isolated from Solanum sisymbriifolium fruits in rodents. Pharmaceutical biology. 2011;49(2):194-9. 68. Chidrawar Vijay R, Patel Krishnakant N, Sheth Navin R, Shiromwar Shruti S, Trivedi Piyush. Antiobesity effect of Stellaria media against drug induced obesity in Swiss albino mice. Ayu. 2011;32(4):576. 69. Dabhi Mahesh R, Gohel Mukesh, Parikh Rajesh, Sheth Navin R, Nagori Stavan. Formulation development of ambroxol hydrochloride soft gel with application of statistical experimental design and response surface methodology. PDA Journal of Pharmaceutical Science and Technology. 2011;65(1):20-31. 70. Dabhi Mahesh R, Limbani Milan D , Sheth Navin R. Preparation and in vivo evaluation of self- nanoemulsifying drug delivery system (SNEDDS) containing ezetimibe. Current Nanoscience. 2011;7(4):616-27. 71. Dabhi Mahesh R , Nagori Stavan A , Sheth Navin R, Patel Nilesh K, Dudhrejiya Ashvin V. Formulation optimization of topical gel formulation containing micro-emulsion of terbinafine hydrochloride with simplex lattice design. Micro and Nanosystems. 2011;3(1):1-7. 72. Dangi Amish , Sorathiya Ddhaval, Sheth Navin R, Bagthariya S, Solanki S, Chavda A. Preparation and characterization of solid lipid nanoparticle loaded with rosiglitazone maleate. Inventi Impact: NDDS. 2011. 73. Dangi Amish A, Sheth Navin R, Patel H J, Shukla T M, Patel H M. Formulation and evaluation of once daily mucoadhesive vaginal tablet of clotrimazole using natural and synthetic polymers. Asian J Pharm Health Sci. 2011;1:176-82. 74. Dangi Amish A, Sheth Navin R, Sodha Hima H, Joshi Purvi C, Bhalodiya Divyesh S, Panchal Ankita C, Ramanuj Pooja R. Formulation and development of vaccines and their selection for next generation. Bulletin of Pharmaceutical Research. 2011;1(3):49-62. 75. Dangi Amish A, Sorathiya Dhaval, Sheth Navin R, Bagthariya Subhash H, Solanki Sagar M, Chavda Ajay. Preparation and Characteristic of Solid Lipiq Nanoparticles Loaded With Rosiglitazone Maleate. Inventi Rapid: NDDS. 2011;2011(3). 76. Dedania Zarna R, Dedania Ronak R, Sheth Navin R, Gajra Balram, Patel Jigar. Development and Validation of A Stability-Indicating High Performance Liquid Chromatography Assay for Aripiprazole in Bulk Drug Substance. Asian J Pharm Biol Res Apr-Jun. 2011;1(2). 77. Dedania Zarna R, Dedania Ronak R, Sheth Navin R, Patel Jigar B, Patel Bhavna. Stability indicating HPLC determination of Risperidone in bulk drug and pharmaceutical formulations. International journal of analytical chemistry. 2011;2011. 78. Gohel Mital K, Sheth Navin R, Dudhrejiya Ashvin V. Anticonvulsant activity of extract from the seeds of Vigna mungo (L.) Hepper. Journal of Pharmacy Research. 2011;4(6). 79. Gosai Viral, Ambalam Padma, Raman Maya, Kothari Charmi R, Kothari Ramesh K, Vyas B R, Sheth Navin R. Protective effect of Lactobacillus rhamnosus 231 against N-methyl-N’-nitro-N- nitrosoguanidine in animal model. Gut microbes. 2011;2(6):319-25. 80. Goyal Swapnil, Sureka Shruti, Daniel Kratika, Daniel Vivek, Trivedi Rahul, Deshmukh Pradeep, Sheth Navin R. Evaluation of wound healing effect of a polyherbal formulatio by different cutaneous wound models. Pharmacologyonline. 2011;1(1):973-80. 81. Manek Ravi A, Sheth Navin R, Vaghasiya Jitendra D, Malaviya Shailesh V, Jivani Nurudin P, Chavda Jayant R. Study on herb-herb interaction potential of Glycyrrhiza glabra with Solanum xanthocarpum and Adhatoda vasica on mast cell stabilizing activity. International journal of pharmacology. 2011;7(5):589-98. 82. Parmar Komal R, Satapara Vijay P, Shah Sunny R, Sheth Navin R Improvement of dissolution properties of lamotrigine by inclusion complexation and solid dispersion technique. Die Pharmazie. 2011;66(2):119-23.

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83. Parmar Komal R, Shah Sunny R, Sheth Navin R. Studies in dissolution enhancement of ezetimibe by solid dispersions in combination with a surface adsorbent. Dissolut Technol. 2011;8:55-61. 84. Parmar Komal R, Shah Sunny R, Sheth Navin R. Preparation, characterization, and in vitro evaluation of ezetimibe binary solid dispersions with poloxamer 407 and PVP K30. Journal of Pharmaceutical Innovation. 2011;6(2):107-14. 85. Patel Jaydeep, Kevin Garala, Patel Anjali, Raval Mihir, Sheth Navin. Development of the UV spectrophotometric method of Olmesartan medoxomil in bulk drug and pharmaceutical formulation and stress degradation studies. Pharmaceutical methods. 2011;2(1):36-41. 86. Patel Jaydeep, Patel Anjali, Raval Mihir, Sheth Navin. Formulation and development of a self- nanoemulsifying drug delivery system of irbesartan. Journal of advanced pharmaceutical technology & research. 2011;2(1):9. 87. Patel Jaydeep D, Kevin Garala, Patel Anjali, Raval Mihir K, Sheth Navin R. Design and development of a self-nanoemulsifying drug delivery system for telmisartan for oral drug delivery. International journal of pharmaceutical investigation. 2011;1(2):112. 88. Patel Jaydeep D, Patel Anjali J, Raval Mihir K, Sheth Navin R. Development of UV Spectrophotometric Method of Telmisartan in Bulk Drug and Pharmaceutical Formulation and Stress Degradation Studies. Inventi Rapid: Pharmaceutical Analysis and Quality Assurance. 2011;2011:1-6. 89. Patel Tejas, Dudhrejiya Ashvin D, Sheth Navin R. Anti inflammatory activity of Myrica nagi Linn. Bark. Ancient science of life. 2011;30(4):100. 90. Prajapati R, Kalariya M, Umbarkar R, Parmar S, Sheth N. Colocasia esculenta: A potent indigenous plant. International Journal of Nutrition, Pharmacology, Neurological Diseases. 2011;1(2):90. 91. Prajapati R, Umbarkar R, Parmar S, Sheth N. Antidepressant like activity of Lagenaria siceraria (Molina) Standley fruits by evaluation of the forced swim behavior in rats. International Journal of Nutrition, Pharmacology, Neurological Diseases. 2011;1(2):152. 92. Prajapati Rakesh P, Kalaria Manisha V, Karkare Vaibhavi P, Parmar Sachin K, Sheth Navin R. Effect of methanolic extract of Lagenaria siceraria (Molina) Standley fruits on marble-burying behavior in mice: Implications for obsessive–compulsive disorder. Pharmacognosy research. 2011;3(1):62. 93. Ranpariya Vishavas L, Parmar Sachin K, Sheth Navin R, Chandrashekhar V M. Neuroprotective activity of Matricaria recutita against fluoride-induced stress in rats. Pharmaceutical biology. 2011;49(7):696-701. 94. Senghani Mahesh K, Sukhramani Prakash S, Desai Sarav A, Dudhrejia Ashvin V, Sheth Navin R. Qualitative and Quantitative Standardization of Trikatu Churna. Research Journal of Pharmacognosy and Phytochemistry. 2011;3(4):154-7. 95. Shah Vipul K, Shah Vrunda V, Sheth Navin R, Patel Krishnakant N. Antioxidant activity of root of Ipomoea turpethum Linn. Inventi Rapid: Ethnopharmacology. 2011. 96. Shah Vipul K, Shah Vrunda V, Sheth Navin R, Shah Dushyant A. Pharmacognostical and phytochemical evaluation of the Ipomoea turpethum root. Inventi Rapid: Pharm Ana & Qual Assur. 2011. 97. Sitapara Neha, Buch Prakruti, Dudhrejiya Ashvin D, Sheth Navin R. Standardization of Caturjata Churna-An Ayurvedic Polyherbal Formulation. IJPI’SJ Pharmacog Herbal Formulations. 2011;1:57- 62. 98. Ushir Yogesh V, Patel Krishnakant, Sheth Navin R. Analysis of Fatty Acid in Anisomeles Species by Gas Chromatography-Mass Spectrometry. Pharmacognosy Journal. 2011;3(22):44-7. 99. Ushir Yogesh V, Patel Krishnakant N, Sheth Navin R. HPTLC Fingerprint Profile for Quantitative Determination of Various Phytoconstituents in Anisomeles Species. American Journal of Pharmtech Research. 2011;1(3):283-90.

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100. Vaghasiya Jitendra D, Sheth Navin R, Bhalodia Yagnik S, Manek Ravi. Sitagliptin protects renal ischemia reperfusion induced renal damage in diabetes. Regulatory peptides. 2011;166(1):48-54. 101. Vaishnav Devendra J, Sheth Jayesh J, Sanghvi Riddhi N, Sanghavi Gaurav V, Sheth Navin R. Studies on screening of pro12ala snp in pparγ2 gene among gujarat subjects. American journal of PharmTech Research. 2011;1:1-6. 102. Vyas A J, Patel Jayvadan K, Bhandari A, Chavda Jayant R, Sheth Navin R. Simultaneous Estimation of Lornoxicam and Paracetmaol by Vierodt’s Method in API and in Synthetic mixture. International Journal of ChemTech Research. 2011;3(3):1269-73. 103. Barochiya Nirju, Raval Mihir, Sheth Navin. Method development and validation for simultaneous estimation of metoprolol succinate and telmisartan in combined dosage form by high performance thin layer chromatography. Inventi Rapid: Pharm Ana & Qual Assur. 2012. 104. Barochiya Nirju, Raval Mihir, Sheth Navin. Method development and validation for simultaneous estimation of rosuvastatin calcium and telmisartan in combined dosage form by high performance thin layer chromatography. Inventi Rapid: Pharm Ana & Qual Assur. 2012. 105. Barochiya Nirju, Raval Mihir K, Sheth Navin R. Development and validation of first order derivative spectrophotometric method for simultaneous estimation of metoprolol succinate and telmisartan in tablet dosage form. Inventi Rapid: Pharm Analysis & Quality Assurance. 2012. 106. Barochiya Nirju, Raval Mihir K, Sheth Navin R. Development and validation of first order derivative spectrophotometric method for simultaneous estimation of rosuvastatin calcium and telmisartan in tablet dosage form. Inventi Rapid: Pharm Ana & Qual Assur. 2012. 107. Buch Prakruti, Patel Vishal, Ranpariya Vishavas L, Sheth Navin R, Parmar Sachin K. Neuroprotective activity of Cymbopogon martinii against cerebral ischemia/reperfusion-induced oxidative stress in rats. Journal of ethnopharmacology. 2012;142(1):35-40. 108. Dhudhrejiya Ashvin V, Bagda Aarti A, Sheth Navin R. Method Development and Validation for Simultaneous Estimation of Amlodipine Besylate and Clopidogrel Bisulphate in Combined Dosage Form by High Performance Thin Layer Chromatography. Inventi Rapid: Pharm Ana & Qual Assur. 2012;2012(3):1-5. 109. Dhudhrejiya Ashvin V, Bhatt S B, Sheth Navin R. Method Development and Validation for Simultaneous Estimation of Amlodipine Besylate and Clopidogrel Bisulphate in Combined Dosage Form by UV Spectrophotometry. inventi Rapid: Pharmaceutical Analysis & Quality Assurance. 2012;2012(3):1-4. 110. Dudhregiya Ashvin V, Bagda Aarti A, Sheth Navin R. Method Development and Validation for Simultaneous Estimation of Amlodipine Besylate and Clopidogrel Bisulphate in Combined Dosage Form by High Performance Liquid Chromatography. Inventi Rapid: Pharmaceutical Analysis & Quality Assurance. 2012;2012(3):1-5. 111. Dudhregiya Ashvin V, Chotaliya Pradip, Sheth Navin R. Method Development and Validation for Simultaneous Estimation of Ambroxol HCL and Roxithromycin in Combined Dosage Form by High Performance Thin Layer Chromatography. Inventi Rapid: Pharmaceutical Analysis & Quality Assurance 2012;2012(3):1-5. 112. Gupta Arti, Sheth Navin R, Pandey Sonia, Yadav Jitendra S, Shah D R, Vyas B, Joshi S. Evaluation of protective effect of Butea monosperma (lam.) Taub in experimental hepatotoxicity in rats. Journal of pharmacology & pharmacotherapeutics. 2012;3(2):183. 113. Kansagra Parth, Sanghvi Gaurav V, Purohit Paresh V, Vachani Ashish N, Sheth Navin R, Vaishnav Devendra J. Development and Validation of stability Indicating UV Spectrophotometric Method for the Determination of Ketoconazole Both in Bulk and Marketed Dosage Formulations. Inventi Rapid: Pharm Analysis & Quality Assurance. 2012;2013(1). 114. Mulsa Nilesh, Sanghvi Gaurav V, Purohit Paresh V, Sheth Navin R, Vaishnav Devendra J. Development of the UV Spectrophotometric Method of Phenytoin Sodium in API and Stress Degradation Studies. Inventi Rapid: Pharm Analysis & Quality Assurance. 2012.

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115. Patel Jaydeep, Patel Anjali, Lalani Riddhi, Tilala Jay, Raval Mihir, Sheth Navin. Design and Development of Nanoparticulate Dosage Form of Telmisartan for Bioavailability Enhancement. Micro and Nanosystems. 2012;4(2):145-56. 116. Patel Jaydeep D, Patel Anjali, Garala Kevin, Raval Mihir K, Sheth Navin R. Development and Validation of a Bioanalytical HPLC Method for Estimation of Irbesartan in Rat Plasma: Application to Pharmacokinetic Studies. Inventi Rapid: Biomedical Analysis. 2012. 117. Rao Priya S, Sheth Navin R, Jayaveera K N. An important spice, Pimenta dioica (Linn.) Merill: A review. International Current Pharmaceutical Journal. 2012;1(8):221-5. 118. Rao Priya S, Sheth Navin R, Jayaveera K N. HPTLC analysis of the essential oil from Pimenta dioica leaf. Journal of Applied Pharmaceutical Science. 2012;2(12):141-8. 119. Rao Priya S, Sheth Navin R, Jayaveera K N. Anthelmintic activity of essential oil of Pimenta dioica (Linn.) Merill, Family: Myrtaceae, collected in Summer from South Canara, India. European Journal of Experimental Biology. 2012;2(6):2271-5. 120. Shukla Riddhi, Sharma Tejas P, Airao Vishal B, Sheth Navin R, Ranpariya Vishvash L, Parmar Sachin K. Neuroprotective activity of Solasodine isolated from Solanum sisymbriifolium Lam. Fruits on Ischemia/Reperfusion-induced Cerevral Injury in Rats. Indian Journal of Pharmacology. 2012;44(S2). 121. Thakur Lovely, sitapara Neha, sheth Navin R. Identification and standardization of Tecoma stans Linn. through transverse section, phytochemical investigation and powder characteristics determination of roots. International Journal of Pharmacy & Pharmaceutical Sciences. 2012;4. 122. Bhalodia Payal N, Parmar Nisha, Sheth Navin R, Dave Param, editors. Evaluation of efficacy and tolerability of panchgavya ghrita in epilepsy patients. Indian Journal of Pharmacology; 2013. 123. Chauhan Sanjay P, Sheth Nnavin R, Rathod I S, Suhagia B N, Maradia Rajnikant B. Analysis of betalains from fruits of Opuntia species. Phytochemistry Reviews. 2013;12(1):35-45. 124. Dabhi Mahesh R, Sheth Navin R. Formulation development of physiological environment responsive periodontal drug delivery system for local delviery of metronidazole benzoate. Drug development and industrial pharmacy. 2013;39(3):425-36. 125. Davra Kajal, Bhatt Rohit, Sharma Tejas P, Sheth Navin R, Parmar Sachin K, editors. Ellagic acid protects rat brain against 6-ohda induced parkinsonian-like symptoms through its antioxidant activity. Indian journal of pharmacology; 2013. 126. Dedania Zarna R, Sheth Navin R, Dedania Ronak R. Stability indicating high-performance thin- layer chromatographic determination of quetiapine fumarate. International Journal of Pharmaceutical Sciences & Research. 2013;4(6). 127. Dungarani Jitendra P, Sanghvi Gaurav V, Purohit Paresh V, Vachhani Ashish N, Sheth Navin R, Vaishnav Devendra J. Development and validation of the UV spectrophotometric method of diclofenac potassium in API and stress degradation studies. Inventi Rapid: Pharm Analysis & Quality Assurance. 2013. 128. Goyal Swapnil, Sheth Navin R, Srivastava D N. Evaluation of anti-inflammatory activity of various fractions from ethanolic extract of Nyctanthes arbor-tristis leaves and characterization of its bioactive fraction by thin layer chromatography. Inventi Impact: Ethnopharmacology. 2013. 129. Gupta Arti, Sheth Navin R, Pandey Sonia, Shah Dinesh R, Yadav Jitendra S. Design and evaluation of herbal hepatoprotective formulation against paracetamol induced liver toxicity. Journal of Young Pharmacists. 2013;5(4):180-7. 130. Gupta Arti, Sheth Navin R, Pandey Sonia, Shah Dinesh R, Yadav Jitendra S. Determination of ursolic acid in fractionated leaf extracts of Ocimum gratissimum Linn and in developed herbal hepatoprotective tablet by HPTLC. Pharmacognosy Journal. 2013;5(4):156-62. 131. Joshi Krishna G, Trivedi Aarti P, Sheth Navin R, Bhalodia Payal N, editors. Observational Cross- Sectional Study of Clinico-Epidemiological Factors in Patients of Various Metabolic Disorders in Government Hospital of Rajkot. Indian journal of pharmacology; 2013.

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132. Patel Jaydeep D, Dhingani Anjali, Garala Kevin, Raval Mihir K, Sheth Navin R. Quality by design approach for oral bioavailability enhancement of Irbesartan by self-nanoemulsifying tablets. Drug delivery. 2013(0):1-24. 133. Patel Jaydeep D, Dhingani Anjali P, Garala Kevin C, Raval Mihir K, Sheth Navin R. Development and Validation of Bioanalytical HPLC Method For Estimation of Telmisartan In Rat Plasma: Application To Pharmacokinetic Studies. Dhaka University Journal of Pharmaceutical Sciences. 2013;11(2):121-7. 134. Paun Jalpa S, Raval MK, Tank HM, Sheth NR. Influence of solvents and processing conditions on crystal habit and properties of aceclofenac. Inventi Rapid: Pharm Tech. 2013. 135. Paun Jalapa S, Raval Mihir K, Tank H M, Sheth Navin R. Optimization of Solvents and Processing Conditions for Crystallization of Aceclofenac. Asian Journal of Research in Pharmaceutical Science. 2013;3(3):122-32. 136. Prajapati Rakesh P, Karkare Vaibhavi P, Kalaria Manisha V, Parmar Sachin K, Sheth Navin R. Pharmacognostic and phytochemical evaluation of the Solanun sisymbriifolium leaf. African Journal of Biotechnology. 2013;12(42):6133-9. 137. Rajyaguru Chandni, Chavda Shilpa, Sheth Navin R, Rabadiya Samir O, editors. Beneficial Role of Syringic acid on Cardiovascular and Renal Complications Associated with Type I Diabetes Mellitus in Rats. Indian journal of pharmacology; 2013. 138. Raval Mihir K, Patel Jaydeep M, Parikh Rajesh K, Sheth Navin R. Studies on Influence of Polymers and Excipients on Crystallization Behavior of Metformin Hcl to Improve the Manufacturability. Particulate Science and Technology. 2013(just-accepted). 139. Raval Mihir K, Ramani Riddhi V, Sheth Navin R. Formulation and evaluation of sustained release enteric-coated pellets of budesonide for intestinal delivery. International journal of pharmaceutical investigation. 2013;3(4):203. 140. Raval Mihir K, Sorathiya Kishor R, Chauhan Narendra P, Patel Jaydeep M, Parikh Rajesh K, Sheth Navin R. Influence of polymers/excipients on development of agglomerated crystals of secnidazole by crystallo-co-agglomeration technique to improve processability. Drug development and industrial pharmacy. 2013;39(3):437-46. 141. Sankhavara Mital H, Shukla Riddhi H, Sheth Navin R, Rabadiya Samir O, editors. Evaluation of the Anti-Diabetic Activity of An Ayurvedic Formulation Comprising Vijaysar and Gaumutra in Experimental Animals. Indian journal of pharmacology; 2013. 142. Shah Sunny R, Parikh Rajesh H, Chavda Jayant R, Sheth Navin R. Self-nanoemulsifying drug delivery system of glimepiride: design, development, and optimization. PDA Journal of Pharmaceutical Science and Technology. 2013;67(3):201-13. 143. Shah Sunny R, Parikh Rajesh H, Chavda Jayant R, Sheth Navin R. Application of Plackett–Burman screening design for preparing glibenclamide nanoparticles for dissolution enhancement. Powder technology. 2013;235:405-11. 144. Chauhan Sanjay P, Sheth Navin R, Suhagia B N. Haematinic evaluation of fruits of Opuntia elatior mill. On mercuric chloride induced anemia in rats. International Journal of Research in Ayurveda & Pharmacy. 2014;5(1). 145. Dabhi Mahesh R, Sheth Navin R. Optimization of Novel Mucoadhesive In Situ Film Forming Periodontal Drug Delivery System for Chemotherapeutic Agents. Journal of Pharmaceutical Innovation. 2014;9(2):83-94. 146. Dudhrejiya Ashvin V, Gandhi Karishma, Maru Meera, Sheth Navin R. Development and validation of stability indicating RP-HPLC method for simultaneous estimation of sildenafil citrate and fluoxetine in bulk & tablet dosage form. International Bulletin of Drug Research. 2014;4(6):92-105. 147. Manek Ravi A, Sheth Navin R, Chavda Jayant R, Vaghasiya Jitendra D, Modi K P, Patel Dhaval. Liquorice exaggerates protective action of Solanum xanthocarpum against cigarette smoke induced pulmonary inflammation. Planta Medica. 2014;80(10):PP13.

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148. Panchal Ankita, Sanghvi Gaurav V, Vachhani Ashish N, Sheth Navin R, Vaishnav Devendra J. Simultaneous determination of Aspirin and Rosuvastatin Calcium in capsules by using RP-HPLC coupled with photo diode array detection. International Letters of Chemistry, Physics and Astronomy. 2014;14(2):218-30. 149. Parmar Komal , Patel Jayvadan K, Sheth Navin R. Fabrication and characterization of liquisolid compacts of Embelin for dissolution enhancement. Journal of Pharmaceutical Investigation. 2014:1-8. 150. Patel Jaydeep, Dhingani Anjali, Tilala Jay, Raval Mihir, Sheth Navin. Formulation and Development of Self-Nanoemulsifying Granules of Olmesartan Medoxomil for Bioavailability Enhancement. Particulate Science and Technology. 2014;32(3):274-90. 151. Patel Jaydeep D, Dhingani Anjali, Garala Kevin, Raval Mihir K, Sheth Navin R. Design and development of solid nanoparticulate dosage forms of telmisartan for bioavailability enhancement by integration of experimental design and principal component analysis. Powder Technology. 2014;258:331-43. 152. Shah Sunny R, Parikh Rajesh H, Chavda Jayant R, Sheth Navin R. Glibenclamide Nanocrystals for Bioavailability Enhancement: Formulation Design, Process Optimization, and Pharmacodynamic Evaluation. Journal of Pharmaceutical Innovation. 2014:1-11. 153. Sharma Tejas P, Airao Vishal B, Panara Nimesh, Vaishnav Devendra J, Ranpariya Vishavas L, Sheth Navin R, Parmar Sachin K. Solasodine protects rat brain against ischemia/reperfusion injury through its antioxidant activity. European journal of pharmacology. 2014;725:40-6. 154. Vaishnav Devendra J, Suthar Janak, Oza Tejas G, Dave Gaurav S, Sheth Navin R, Sanghvi Gaurav V. A statistical approach for the enhanced production of thermostable alkaline protease showing detergent compatibility activity from Bacillus circulans. Biocatalysis and Biotransformation. 2014;32(3):151-60 Projects

1. Gujarat Council of Science & Technology (GUJCOST), Gandhinagar accepted my project titled ‘Clinical investigation of Solnum xanthocarpum’ and sanctioned Rs. 50,000/- (Fifty thousands) in August 2003 and completed in 2005. 2. Major research project titled “Phytopharmacological study of a folkloric plant for diuretic property” submitted to Govt. of Gujarat. 3. Gujarat Council of Science & Technology (GUJCOST), Gandhinagar accepted my project titled ‘To assess the prevalence and attributable risk factors of Diabetes Mellitus in western Indian population’ year 2007-2009, sanctioned Rs. 2,55,000.00 (Two lacks and Fifty-five thousands only) 4. Major research project titled “Studies on optimization of the crystal habit and improvement on processing and pharmacokinetic parameters of selected active pharmaceutical ingredients” of Rs. 3,29,000/- sanctioned by UGC. 5. Extra mural research project titled “Bio-molecules from Ficus racemose (Linn.) and Alstonia scholaris (Linn.) influencing cardiac protection and their role in the management of diabetic cardiomyopathy” of Rs. 21,00,000/- sanctioned by ICMR. Letter no. 59/21/2013.BMS/TRM dated on 23rd February, 2015.

Dr. Mihir Raval

1. Bryce, D. M., and R. Smart. "The preservation of shampoos." J. Soc. Cosmetic Chemists 1.6 (1965): 187-201.

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2. Sanja, S. D., Sheth, N. R., Joshi, D. M., Golwala, D. K., & Patel Dhaval, R. M. (2009). Anti Inflammatory Activity of Ipomoea reniformis Methanolic Extract. International Journal of Pharmaceutical Sciences and Drug Research, 1(3). 3. Golwala, D. K., Patel, L. D., Bothara, S. B., Patel, P. M., Vaidya, S. K., & Raval, M. K. (2009). Analgesic activity of ethanolic leaf extract of Pavetta indica. Int J Pharm Sci Drug Res, 1, 119- 120. 4. Paun, J. S., Raval, M. K., Tank, H. M., & Sheth, N. R. (2013). INFLUENCE OF SOLVENTS AND PROCESSING CONDITIONS ON CRYSTAL HABIT AND PROPERTIES OF ACECLOFENAC. Inventi Rapid: Pharm Tech. 5. M. K. Raval, D. Mer, A. V. Dudhrejiya, Jaydeep Patel, N. R. Sheth, Rajesh Parikh (2011). Study of Modulation of Papain Release from Enteric Coated Beads. VAK, 6, 113-125 6. Raval, M. K., Bagda, A. A., Patel, J. M., Paun, J. S., Chaudhari, K. R., & Sheth, N. R. (2010). Preparation and Evaluation of Sustained Release Nimesulide Microspheres Using Response Surface Methodology. Journal of Pharmacy Research, 3(3). 7. Shah, V. K., Zalavadiya, V. I., Sheth, N. R., Raval, M. K., Dudhrejiya, A. V., & Golwala, D. K. (2010). Standardization and Assessment of Preformulation Parameters of Rasayana Tablet. International Journal of Pharmaceutical Sciences and Drug Research, 2(1), 58-62. 8. Paun, J. S., Bagada, A. A., & Raval, M. K. (2010). Nasal Drug Delivery–As An Effective Tool For Brain Targeting-A Review. International Journal Of Pharmaceutical And Applied Sciences/1 (2). 9. Patel, J., Dhingani, A., Dabhi, M., Patel, N., Raval, M., & Sheth, N. (2010). Design and development of sustained release microspheres of Quetiapine Fumarate using 3 2 full factorial design. Journal of Pharmacy Research, 3(12). 10. Raval, M. K., Prajapati, D. U., Varma, S. M., Khodifad, M. A., Patel, J. M., & Sheth, N. R. (2010). Influence of some hydrophilic polymers on dissolution characteristics of furosemide through solid dispersion: An unsatisfied attempt for immediate release formulation. Journal of Pharmaceutical Negative Results, 1(2), 29. 11. Raval, M. K., Chaudrari, K., Shah, B., Patel, J. D., Sheth, N. R., & Parikh, R. K. (2010). FORMULATION AND EVALUATION OF MATRIX TYPE TRANSDERMAL DRUG DELIVERY SYSTEM CONTAINING ONDANSETRON HYDROCHLORIDE. Inventi Rapid: NDDS. 12. Raval, M. K., Sathesh Babu, P. R., Thimmasetty, J., Parikh, R. K., Sheth, N. R., & Subrahmanyam, C. (2010). Influence of solvents on the crystal habit and properties of rofecoxib and celecoxib: No evidence of polymorphism. Journal of Pharmaceutical Negative Results, 1(2), 40. l 13. Patel Jaydeep, Patel Anjali, Raval Mihir, Sheth Navin. (2011). Development of UV Spectrophotometric Method of Telmisartan in Bulk Drug and Pharmaceutical Formulation and Stress Degradation Studies. Inventi Rapid: Pharm Ana & Qual Assur, 2(2), 2011 14. Patel, J., Kevin, G., Patel, A., Raval, M., & Sheth, N. (2011). Development of the UV spectrophotometric method of Olmesartan medoxomil in bulk drug and pharmaceutical formulation and stress degradation studies. Pharmaceutical methods, 2(1), 36-41. 15. Patel, J., Patel, A., Raval, M., & Sheth, N. (2011). Formulation and development of a self- nanoemulsifying drug delivery system of irbesartan. Journal of advanced pharmaceutical technology & research, 2(1), 9. 16. Patel, J., Kevin, G., Patel, A., Raval, M., & Sheth, N. (2011). Design and development of a self- nanoemulsifying drug delivery system for telmisartan for oral drug delivery. International journal of pharmaceutical investigation, 1(2), 112. 17. Patel, J., Garala, K., Basu, B., Raval, M., & Dharamsi, A. (2011). Solubility of aceclofenac in polyamidoamine dendrimer solutions. International journal of pharmaceutical investigation, 1(3), 135.

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18. Potdar, S. Roy, D. Sheth, M. Raval, A. Vyas. (2011). Formulation, Evaluation and optimization of bilayered tablet containing Zilueton. AAPS journal, 13 (S2), 2011 (Annual meeting of 2011) 19. Raval, M. K., Sorathiya, K. R., Chauhan, N. P., Patel, J. M., Parikh, R. K., & Sheth, N. R. (2013). Influence of polymers/excipients on development of agglomerated crystals of secnidazole by crystallo-co-agglomeration technique to improve processability. Drug development and industrial pharmacy, 39(3), 437-446. 20. Patel, J., Patel, A., Lalani, R., Tilala, J., Raval, M., & Sheth, N. (2012). Design and Development of Nanoparticulate Dosage Form of Telmisartan for Bioavailability Enhancement. Micro and Nanosystems, 4(2), 145-156. 21. Patel, J., Garala, K., Dhingani, A., Raval, M., & Dharamsi, A. (2012). SOLUBILITY ENHANCEMENT OF CANDESARTAN BY POLYAMIDOAMINE DENDRIMERS. Inventi Rapid: NDDS. 22. Garala K., Kapadiya M., Patel J, Patel A, Raval M., Dharamsi A. (2013 0 Design and Evaluation of Transdermal Drug Delivery System of 23. Nebivolol Hydrochloride. Inventi Rapid: Pharm NDDS, 2013(1):115. 24. Barochiya, N., Raval, M. K., & Sheth, N. (2012). Development and validation of first order derivative spectrophotometric method for simultaneous estimation of rosuvastatin calcium and telmisartan in tablet dosage form. Inventi Rapid: Pharm Ana & Qual Assur. 25. Barochiya, N., Raval, M., & Sheth, N. (2012). Development and validation of first order derivative spectrophotometric method for simultaneous estimation of metoprolol succinate and telmisartan in tablet dosage form. Inventi Rapid: Pharm Analysis & Quality Assurance. 26. Mihir K Raval, Jasmin M Chikhalia, Mital B Gosai, Kashyap Thumar. (2012). Method development and validation for simultaneous estimation of metoprolol succinate and olmesartan medoxomil in tablet dosage form by high performance thin layer chromatography. Inventi Rapid: Pharm Analysis & Quality Assurance. 27. Raval, M., Chikhalia, J., Gosai, M., & Thumar, K. (2012). Method Development and Validation for Simultaneous Estimation of Metoprolol Succinate and Olmesartan Medoxomil in Tablet Dosage Form by RP-HPLC. Inventi Rapid: Pharm Analysis & Quality Assurance. 28. Barochiya, N., Raval, M., & Sheth, N. (2012). Method development and validation for simultaneous estimation of metoprolol succinate and telmisartan in combined dosage form by high performance thin layer chromatography. Inventi Rapid: Pharm Ana & Qual Assur. 29. Barochiya, N., Raval, M., & Sheth, N. (2012). Method Development And Validation For Simultaneous Estimation Of Rosuvastatin Calcium And Telmisartan In Combined Dosage Form By High Performance Thin Layer Chromatography. Inventi Rapid: Pharm Ana & Qual Assur. 30. Garala, K., Patel, J., Patel, A., Raval, M., & Dharamsi, A. (2012). Influence of excipients and processing conditions on the development of agglomerates of racecadotril by crystallo-co- agglomeration. International journal of pharmaceutical investigation, 2(4), 189. 31. Dhingani, A., Patel, J., Garala, K., Raval, M., & Dharamsi, A. (2014). Quality by Design Approach for Development of W/O Type Microemulsion-Based Transdermal Systems for Atenolol. Journal of Dispersion Science and Technology, 35(5), 619-640. 32. Raval, M. K., Ramani, R. V., & Sheth, N. R. (2013). Formulation and evaluation of sustained release enteric-coated pellets of budesonide for intestinal delivery. International journal of pharmaceutical investigation, 3(4), 203. 33. Patel, J., Dhingani, A., Garala, K., Raval, M., & Sheth, N. (2014). Quality by design approach for oral bioavailability enhancement of Irbesartan by self-nanoemulsifying tablets. Drug delivery, 21(6), 412-435. 34. Patel, J., Dhingani, A., Tilala, J., Raval, M., & Sheth, N. (2014). Formulation and Development of Self-Nanoemulsifying Granules of Olmesartan Medoxomil for Bioavailability Enhancement. Particulate Science and Technology, 32(3), 274-290.

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35. Raval, M. K., Patel, J. M., Parikh, R. K., & Sheth, N. R. (2014). Studies on Influence of Polymers and Excipients on Crystallization Behavior of Metformin HCl to Improve the Manufacturability. Particulate Science and Technology, 32(5), 431-444. 36. Patel, J., Patel, A., Garala, K., Raval, M., & Sheth, N. (2012). Development and Validation of a Bioanalytical HPLC Method for Estimation of Irbesartan in Rat Plasma: Application to Pharmacokinetic Studies. Inventi Rapid: Biomedical Analysis. 37. Patel, J., Dhingani, A., Garala, K., Raval, M., & Sheth, N. (2014). Design and development of solid nanoparticulate dosage forms of telmisartan for bioavailability enhancement by integration of experimental design and principal component analysis. Powder Technology, 258, 331-343. 38. Patel, P., Raval, M., & Sheth, N. (2014). Nanoparticulate Drug Delivery Sytem for Cancer Therapy: Oppourtunities and Challenges. Recent Patents on Nanomedicine, 4(1), 32-45. 39. Satani, R. R., RAVAL, M., & SHETH, N. (2014). Design And Development Of Compressed Coated As Chronomodulated System For Hypertension. International Bulletin of Drug Research, 4, 45-59. 40. Mihir K. Raval, Jaydeep M. Patel, Rajesh K. Parikh, Navin R. Sheth. (2015) Dissolution Enhancement of Chlorzoxazone using Cogrinding Technique International journal of Pharmaceutical Investigation, 5 (4); 247-258. 41. Raval, M. K., Vaghela, P. D., Vachhani, A. N., & Sheth, N. R. (2015). Role of excipients in the crystallization of Albendazole. Advanced Powder Technology. 26 (4); 1102-1115. Project

1. Major research project titled “Studies on optimization of the crystal habit and improvement on processing and pharmacokinetic parameters of selected active pharmaceutical ingredients” of Rs. 3, 29,000/- sanctioned by UGC in May 2009. 2. UGC Sponsored “SPECIAL ASSISTANCE PROGRAMME (SAP)” has been granted for the tenure of 5 years (1st April 2011 to 31st March 2016) of worth Rs. 71.50 Lacs with one Research Fellow. 3. GUJCOST Sponsored Minor research project on “Poly herbal formulation for the treatment of mild to moderate Psoriasis: An open label pilot study” from March 2013 to March 2015 of worth Rs. 2.00 Lacks 4. Saurashtra University sponsored Seed Money Project on Solid State Characterization and Manufacturability Improvement of Some of the Class-II Drug with Poor Mechanical Properties from March 2013 to March 2015 worth of Rs. 50, 000/-.

Dr. Sachin Parmar

1. Buch PR, Patel VL, Ranpariya VL, Sheth NR, Parmar SK. (2012) Neuroprotective activity of Cymbopogon martinii against cerebral Ischemia/reperfusion-induced oxidative stress in rats, Journal of Ethnopharmacology, 142, 35-40. 2. Ranpariya VL, Parmar SK, Sheth NR, Chandrashekhar VM. (2011). Neuroprotective activity of Matricaria recutita against fluoride-induced stress in rats. Pharmaceutical Biology, 49(7):696-701. 3. Kalariya M, Parmar SK, Sheth NR. (2010). Neuropharmacological activity of hydroalcoholic extract of leaves of Colocasia esculenta. Pharmaceutical Biology, 48(11):1207-1212. 4. Chauhan K, Ranpariya VL, Sheth NR, Parmar SK. (2010). Anticonvulsant activity of solasodine isolated from Solanum sisymbriifolium fruits in rodents. Pharmaceutical Biology, 49(2), 194-199. 5. Parmar SK, Gangwal AP, Prajapati TR, Pandya KB, Ranpariya VL, Sheth NR. (2010). Evaluation of anti-asthmatic activity of ethanolic extract of Solanum xanthocarpum leaves. Pharmacologyonline, 2:410-424.

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6. Parmar SK, Gangwal AP, Sheth NR. (2010). Solanum xanthocarpum (Yellow berried night shade)-A review. Der Pharmacia Lettre, 2(4): 373-383. 7. Gangwal AP, Parmar SK, Sheth NR. (2010). Triterpenoid, flavonoids and sterols from Lagenaria siceraria fruits. Der Pharmacia Lettre, 2(1), 307-317. 8. Prajapati RP, Kalariya MV, Karkare VP, Parmar SK, Sheth NR. (2011). Effect of methanolic extract of Lagenaria siceraria (Molina) Standley fruits on marble-burying behavior in mice: Implications for obsessive–compulsive disorder. Pharmacognosy Research, 3(1), 62-66. 9. Parmar SK, Gangwal AP, Sheth NR. (2010). Mast cell membrane stabilization and anti-histaminic actions- possible mechanism of action of anti-inflammatory action of Murraya koenigii. Journal of Current Pharmaceutical Research, 2(1): 21-25. 10. Parmar SK, Gangwal AP, Sheth NR. (2010). Evaluation of antiasthmatic activity of a polyherbal formulation containing four plant extracts. Journal of Current Pharmaceutical Research, 2(1): 40- 44. 11. Prajapati RP, Kalariya MV, Parmar SK, Sheth NR. (2010). Phytochemical and pharmacological review of Lagenaria siceraria Journal of Ayurveda and Integrative Medicine, 1(4), 266-272. 12. Gangwal AP, Parmar SK, Sheth NR. (2010). Phytochemical investigation and immunomodulatory activity of Lagenaria siceraria fruits. Journal of Natural Remedies. 10(2): 180-184. 13. Sanandia JR, Parmar SK, Sheth NR. (2009). Pharmacognostical study of Cymbopogon martini (Roxb.) Watson. Journal of Herbal Medicine and Toxicology, 3(2), 99-103. 14. Gangwal AP, Parmar SK, Sheth NR. (2009). Isolation and immunomodulatory activity of phytoconstituents of Lagenaria siceraria. InPharm Communique 2(2), 46-50. 15. Parmar SK, Kathad HK, Gangwal AP, Sheth NR. (2009). Evaluation of anti-asthmatic activity of leaves of Murraya koenigii L. B.V.U. Scientific and Research Journal, 6, 15-21. 16. Kalaria MV, Gangwal AP, Parmar SK, Sheth NR. (2009). Isolation and immunomodulatory activity of phytoconstituents of Lagenaria siceraria fruits. B.V.U. Scientific and Research Journal, 6, 15- 21. 17. Gangwal AP, Parmar SK, Mardia RB, Sheth NR. (2008).Immunomodulatory activity of saponin mixture isolated from Lagenaria siceraria fruits. Nigerian Journal of Natural Products and Medicine, 12, 43-46. 18. Gangwal AP, Parmar SK, Sheth NR. (2008). Immunomodulatory effects of Lagenaria siceraria fruits in rats. Pharmacognosy Magazine, 4, S240-244. Projects

1. Seed Money Project 2009-10 for Young Scientists sponsored by Saurashtra University, Rajkot 2. Innovative Program (Sponsor by University Grant Commission, New Delhi) Dr. Vaibhav Bhatt

1. V.D. Bhatt, V.B. Ahir, P.G. Koringa, S.J. Jakhesara, D.N. Rank, D.S. Nauriyal, A.P. Kunjadia, C.G. Joshi (2011). Milk Microbiome Signatures of Subclinical Mastitis-Affected Cattle Analyzed by Shotgun Sequencing. Journal of Applied Microbiology. 112 (4): 639–650 (IF: 2.36) 2. V.D. Bhatt, S.S. Dande, N.V. Patil and C.G. Joshi (2013). Molecular analysis of the bacterial microbiome in the forestomach fluid from the dromedary camel (Camelus dromedarius). Molecular Biology Reports. 40(4): 3363-3371. (IF: 2.9) 3. V.D. Bhatt, M.M. Patel, C.G. Joshi, A.P. Kunjadia (2011). Identification and Antibiogram of Microbes Associated With Bovine Mastitis. Animal Biotechnology, 22(03): 163 -169. (IF: 0.92) 4. V.D. Bhatt, Y.H. Vaidya, P.D. Kunjadia and A.P. Kunjadia (2012). Isolation and charecterization of probiotic bacteria from human milk. International journal of pharmaceutical science and health care. 2(3): 62-70.

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5. V.D. Bhatt, P.S. Khade, S.B. Tarate, A.K. Tripathi, D.S. Nauriyal, D.N. Rank, A.P. Kunjadia and C.G. Joshi (2012). Cytokine expression pattern in milk somatic cells of Subclinical mastitis- affected cattle analyzed by real time PCR. Korean Journal of Veterinary Research. 52(4): 231- 238. 6. V.D. Bhatt and D.N. Rank (2011) Overview of Next Generation Sequencing Technologies. In Joshi C.G. (ed) "Whole genome sequencing in animal and plant research" Agrotech Publishing Academy, Udaipur, India. 7. V.D. Bhatt, B.B. Pandya, C.G. Joshi and A.P. Kunjadia (2013). Curcuma longa: An Alternative to Antibiotics to Combat Mastits in Cattle. Waymba journal of animal science. 5: p582-589. 8. V.D. Bhatt, A.P. Kunjadia, K.D. Bhatt, N.R. Sheth and C.G. Joshi (2014). Analysis of virulence associated and antibiotic resistance genes of microbes in subclinical mastitis affected cattle milk by pyrosequencing approach. Journal of Veterinary Sciences and Medical Diagnosis (Accepted). 9. V.D. Bhatt, T.M. Shah, D.S. Nauriyal, A. P. Kunjadia and C.G. Joshi. Evaluation of a Topical Herbal Drug for Its In-Vivo Immunomodulatory Effect on Cytokines Production and Antibacterial Activity in Bovine Subclinical Mastitis. An International Quarterly Journal of Research in Ayurveda (Accepted). 10. C.G. Joshi, V. Shankar, C. Haritha, S. Shah, M.R. Sajnani, A.K. Patel, V.D. Bhatt, A.K. Tripathi, S.J. Jakhesara, V.B. Ahir (2012). Transcriptome Analysis of Human Buccal Mucosal Cancer. International Journal of Radiation Oncology Biology Physics. 84(3):S709-710. (IF: 4.10) 11. C. Rawal, V.H. Raval, H.D. Bhimani, D.V. Bhensdadia, C.R. Kothari, A.B. Patel, V.D. Bhatt, N.R. Parmar, M.R. Sajnani, P.G. Koringa, C.G. Joshi, R.K. Kothari, and S.P. Singh. (2012). Whole genome shotgun sequencing of extremophile Alkalibacillus haloalkaliphilus C-5 of Indian origin. Journal of Bacteriology. 194(17): 4775 (IF: 3.94) 12. J.B. Prajapati, C.D. Khedkar, J. Chitra, S. Senan, V. Mishra, V. Sreeja, R.K. Patel, V.B. Ahir, V.D. Bhatt, Sajnani MR, Jakhesara SJ, Koringa PG, Joshi CG (2011). Whole genome shotgun sequencing of Indian origin strain of Lactobacillus helveticus MTCC 5463 with probiotic potential. Journal of Bacteriology. 193: 4282–4283. (IF: 3.94) 13. J.B. Prajapati, C.D. Khedkar, J. Chitra, Senan Suja, V. Mishra, V. Sreeja, R.K. Patel, V.B. Ahir, V.D. Bhatt, M.R. Sajnani, S.J. Jakhesara, P.G. Koringa, and C.G. Joshi (2011). Whole genome shotgun sequencing of Lactobacillus rhamnosus MTCC 5462 with probiotic potential. Journal of Bacteriology. 194: 1264-1265. (IF: 3.94) 14. V.B. Ahir, A. Roy, M.K. Jhala, B.B. Bhanderi, R.A. Mathakiya, V.D. Bhatt, K.B. Padiya, S.J. Jakhesara, P.G. Koringa, and C. Joshi.(2011). A Genome Sequence of Pasteurella multocida gallicida Anand1_poultry. Journal of Bacteriology, 193: 5604 (IF: 3.94) 15. Tripathi, A.K., Koringa, P.G., Jakhesara, S.J., Ahir, V.B., Ramani, U.V., Bhatt, V.D., Sajnani, M.R., Patel, D.A., Joshi, A.J., Shanmuga, S.J, Rank, D.N, Joshi, C.G. (2011). A preliminary sketch of horn cancer transcriptome in Indian Zebu cattle. Gene. 493: 124-131 (IF: 2.34) 16. M.B. Vaidya, M.R. Sajnani, U.V. Ramani, A.K. Tripathi, V.D. Bhatt, J.S. Patel, M.M. Patel, V.B. Ahir, K.M. Singh, S.J. Jakhesara, P.G. Koringa, D.N. Rank and C.G. Joshi. (2012) A preliminary analysis of Repetitive Sequence organization in Bubalus bubalis genome. Indian journal of Biotechnology 11(1): 62-66 (IF: 0.55) 17. S.J.Jakhesara, P.G.Koringa, U.V.Ramani, V.B.Ahir, A.K.Tripathi, P.S.Soni, K.M.Singh, V.D.Bhatt, J.S.Patel, M.M.Patel, M.R.Sajnani and C.G.Joshi (2010). Comparative Study of tannin Challenged Rumen Microbiome in Goat Using High Throughput Sequencing Technology. Developmental Microbiology and Molecular Biology, 1 (1): 95-106 18. V.B. Ahir, Koringa, P.G., Bhatt, V.D., Ramani, U.V., Tripathi, A.K., Singh, K.M., Dhagat, U.M., Patel, J.S., Patel, M.M., Katudia, K.H., Sajnani, M.R., Jakhesara, S.J. and Joshi, C.G. (2010). Metagenomic analysis of poultry gut microbes. Indian Journal of Poultry Science, 45(2): 111-114.

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19. M.R. Sajnani, A.K. Patel, V.D. Bhatt, A.K. Tripathi, V.B. Ahir, V. Shankar, S. Shah, K.B. Padiya, T.M. Shah, P.G. Koringa, S.J. Jakhesara, C.G. Joshi (2012). Identification of novel transcripts deregulated in buccal cancer by RNA-seq. Gene, 507 (2): 152-158. (IF: 2.34) 20. S.B. Tarate, P.V. Jadhav, D.D. Ghodigaonkar, P.S. Khade, V.D. Bhatt, A.A. Khan, C.G. Joshi, D.N. Rank (2012). Evaluation of breed-dependent variation in microbial load during subclinical mastitis in cattle using Real Time PCR. Indian Journal of Dairy Science. 65(1):60-65. 21. A.K. Patel, V.D. Bhatt, A.K. Tripathi, M.R. Sajnani, S.J. Jakhesara, P.G. Koringa, C.G. Joshi (2012). Identification of Novel Splice Variants in Horn Cancer by RNA-Seq Analysis in Zebu Cattle. Genomics. 100 (1): 57-63. (IF: 3.33) 22. S.V. Kumar, V.S. Karthik, P. Ragul, R. Aarthi, V.D. Bhatt, P.G. Koringa, T.N. Patel (2011). Genomics and proteomics pyro-sequencing based metagenomics of paddy soils from Uttar Pradesh, India. Journal of Natural Science, Biology and Medicine. 2(2):22. 23. S.J. Jakhesara, P.G. Koringa, V.D. Bhatt, T.M. Shah, S. Vangipuram, S. Shah, C.G. Joshi (2013). RNA-Seq reveals differentially expressed isoforms and novel splice variants in buccal mucosal cancer. Gene, 516:24-32. (IF: 2.34) 24. T.M. Shah, A.K. Patel, V.D. Bhatt, A.K. Tripathi, S. Shah, V. Shankar and C.G. Joshi (2013). The landscape of Alternative splicing in Buccal Mucosa Squmaous Cell Carcinoma. Oral Oncology. 49(6):604-610 (IF: 2.85) 25. D.V. Bhensdadia, H.D. Bhimani, C. Rawal, V. Kothari, V.H. Raval, C.R. Kothari, A.B. Patel, V.D. Bhatt, N.R. Parmar, M.R. Sajnani, P.G. Koringa, C.G. Joshi, S.P. Singh, and R.K. Kothari (2013). Complete Genome Sequence of Escherichia phage ADB-2 Isolated from Fecal Sample of Poultry. Genome Announcement, 1(2): e00043-13. 26. M.R. Sajnani, V.D. Bhatt, C.G. Joshi (2013). Comparing SNPs identification by CLC andSeqMan from transcriptome sequencing data. International Journal of Computational Biology. 4(1): 56-60. (IF: 4.28) 27. P.G. Koringa, S.J. Jakhesara, V.D. Bhatt, A.B. Patel, D. Dash and C.G. Joshi (2013). Transcriptome analysis and SNP Identification in SCC of Horn in (Bos indicus) Indian cattle. Gene. 530(1):119-26. (IF: 2.34) 28. P.G. Koringa, S.J. Jakhesara, V.D. Bhatt, C.P. Meshram, A.K. Patel, D. Fefar, C.G. Joshi (2013). Comprehensive transcriptome profiling of Squamous Cell Carcinoma of Horn in Bos indicus. Veterinary and Comparative Oncology. DOI: 10.1111/vco.12079 (IF: 1.42) 29. V. Kothari, R.K. Kothari, C.R. Kothari, V.D. Bhatt, N.M. Nathani, P.G. Koringa, C. Joshi, B.R.M. Vyas (2013). Genome Sequence of Salt Tolerant Bacillus safensis strain VK, Isolated from Saline Desert Area of Gujarat, India. Genome Announcement. 1(5):e00671-13. 30. N.M. Nathani, S.M. Duggirala, V.D. Bhatt, J. KaPatel and C.G. Joshi (2013). Genomic analysis of Bacillus nealsonii AAU1 strain nov., isolated from Surti buffalo rumen. Advances in Bioscience and Biotechnology. 5: 235-245 (IF: 0.40) 31. A.K. Tripathi, A.K. Patel, R.K. Shah, A.B. Patel, T.M. Shah, V.D. Bhatt, C.G. Joshi (2014). Transcriptomic dissection of myogenic differentiation signature in caprine by RNA-Seq. Mechanism of development. 132: 79-92 (IF: 2.383) 32. K.M. Singh, B. Reddy, A.K. Patel, H. Panchasara, N. Parmar, A.B. Patel, T.M. Shah, V.D. Bhatt, C.G. Joshi (2014). Metagenomic analysis of buffalo rumen microbiome: Effect of roughage diet on Dormancy and Sporulation genes. Meta gene. 2: 252-268 33. S.J. Jakhesara, V.D. Bhatt, N.V. Patel, K.S. Prajapati and C.G. Joshi (2014). Isolation and characterization of H9N2 influenza virus isolates from poultry respiratory disease outbreak. SpringerPlus, (Accepted). doi:10.1186/2193-1801-3-196 34. B.B. Bhanderi, M.K. Jhala, V.B. Ahir, V.D. Bhatt and C.G. Joshi. Cultural and metagenomic based identification of microbiota in subclinical mastitic cows. Animal Biotechnology. (Communicated)

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35. D.S. Sena, V.D. Bhatt, N.V. Patil, C.G. Joshi (2013). Phylogenetic and Functional Analysis of Camel Faecal Microbiome in Extensive Management. (Communicated) 36. D.S. Sena, V.D. Bhatt, N.V. Patil, C.G. Joshi (2013). Molecular analysis of faecal microbial diversity in dromedary camel calves. (Communicated) 37. R. Pandit, V.D. Bhatt, P.D. Kunjadia, A.P. Kunjadia (2013). Real Time PCR assay for study the induction of serine protease gene in A. conoides and D. flagrans a nematode trapping fungi. (Communicated)

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Project

1. Meta-Transcriptome of Milk Microbiome and Pharmacokinetics of Phage Therapy in Treatment of Sub-Clinical and Clinical Bovine Mastitis. Funding Agency: DST; Amount of Fund: 35 Lakh Duration: 5 Years Dr. Nasir Vadia

1. Pharmtechmedica: 2013, 2 (02): 278-281 Development and Validation of Ratio First Derivative UV Spectroscopic Methods for Simultaneous Estimation of Diclofenac sodium and Chlorzoxazone in Synthetic mixture. 2. Inventi Rapid: Pharm Analysis and Quality Assurance: 2013, 03:6-12 HPTLC Method for Estimation of Tramadol hydrochloride and Diclofenac sodium in Synthetic mixture. 3. Inventi Rapid: Pharm Analysis and Quality Assurance: 2013, 03:1-6 UV ratio First Derivative Spectroscopy Method for Simultaneous Estimation of Tramadol hydrochloride and Diclofenac sodium in Solid dosage form. 4. Journal of Applied Pharmaceutical Science: 2013, 3 (03): 24-29. (International Journal- Research paper) Hydrothermal treatment and Mesoporosity of MCM-41 mesoporous nanocomposite. 5. European Journal of Pharmaceutical Sciences: 2012, 45: 8–18. (International Journal- Research paper) Study on Formulation Variables of Methotrexate Loaded Mesoporous MCM-41 Nanoparticles for Dissolution Enhancement. 6. Asian Journal of Pharmaceutical and Clinical Research: 2011, 4 (2): 44-53. (International Journal- Review article) “Mesoporous Material, MCM41: A New Drug Carrier” 7. International Journal of Pharmacy and Pharmaceutical Sciences: 2011, 3 (2): 188-190. (International Journal- Research paper) “Development of Colorimetric Method for Determination of Dasatinib in Bulk and in Tablet Formulation” 8. The International Journal of Chem. tech Research: 2009, 1 (4): 1162-1166. (International Journal- Research Paper) “Simultaneous Spectrophotometric Estimation of Rabeprazole Sodium and Domperidone Maleate in their Combined Pharmaceutical Dosage Form”. 9. The International Journal of Chem. tech Research: 2009, 1 (2): 286-290 (International Journal- Research Paper) “Conventional and Advanced Spectrophotometric Methods for Estimation of Cefetamet pivoxil hydrochloride in Bulk and in Pharmaceutical Formulation”. 10. Indian Journal of Pharmaceutical Science: 2008, 70 (5): 651-659 (National Journal- Research Paper) “Spectrophotometric Determination of Cefetamet pivoxil hydrochloride and Pitavastatin calcium in Pharmaceutical Formulation”. 11. The East and Central African Journal of Pharmaceutical Science: 2007, 10: 3-13 (International Journal- Review Article) “Vaginal Drug Delivery System: A New Option for Administration of Drug” 12. Indian Drugs: 2007, 44 (7): 529-531 (National Journal- Research Paper) “Derivative Spectrophotometric Method of Pitavastatin calcium in Bulk and in 13. Pharmaceutical Formulation”. 14. Indian Journal of Pharmaceutical Science: 2006, 68 (5): 584-587 (National Journal- Research Paper) “Spectrophotometric Determination of Cefetamet pivoxil hydrochloride in Bulk and in Pharmaceutical Formulation”.

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Mr. Devendra Vaishnav

1. Devendra J. Vaishnav*, Jayesh J. Sheth, Riddhi N. Sanghvi, Gaurav V. Sanghavi, Navinchandra R. Sheth, 2011. Studies on screening of prp12ala SNP in pparγ2 gene among gujarat subjects. American Journal of PharmTech Research 1, 1-6. 2. Nilesh Mulsa, Gaurav Sanghvi, Paresh Purohit, Navin Sheth, Devendra Vaishnav*. Development of the UV Spectrophotometric Method of Phenytoin Sodium in API and Stress Degradation Studies. Inventi Rapid: Pharm Analysis & Quality Assurance, 2013(1): 1-5, 2012. 3. Parth Kansagra, Gaurav Sanghvi, Paresh Purohit, Ashish Vachani, Navin Sheth, Devendra Vaishnav*. Development and Validation of Stability Indicating UV Spectrophotometric Method for the Determination of Ketoconazole Both in Bulk and Marketed Dosage Formulations. Inventi Rapid: Pharm Analysis & Quality Assurance, 2013(1):1-5, 2012. 4. Shyam G Sangani, Gaurav V Sanghvi, Paresh V Purohit, Ashish N Vachhani, Navin R Sheth, Devendra J Vaishnav*. Development of the UV Spectrophotometric Method of Tinidazole in API and Stress Degradation Studies. Inventi Rapid: Pharm Analysis & Quality Assurance, 2013(1): 1- 4, 2013. 5. Jitendra P Dungarani, Gaurav V Sanghvi, Paresh V Purohit, Ashish N Vachhani, Navin R Sheth, Devendra J Vaishnav*. Development and Validation of the UV Spectrophotometric Method of Diclofenac Potassium in API and Stress Degradation Studies. Inventi Rapid: Pharm Analysis & Quality Assurance, 2013(2):1-5, 2013. 6. Mendpara, J., Parekh, V., Vaghela, S., Makasana, A., Kunjadia, P. D., Sanghvi, G., Vaishnav, D., & Dave, G. S. (2013). Isolation and characterization of high salt tolerant bacteria from agricultural soil. European Journal of Experimental Biology, 3(6), 351-358. 7. Tejas, S., Vishal, A., Nimesh, P., Devendra, V., Ranpariya, V., Sheth, N., & Parmar, S. (2014). Solasodine protects rat brain against ischemia/reperfusion injury through its antioxidant activity. European Journal of Pharmacology, 725, 40-46 Panchal A, Sanghvi G, Vachhani A, Sheth N, Vaishnav D*. 2014. Simultaneous determination of Aspirin and Rosuvastatin Calcium in capsules by using RP- HPLC coupled with photo diode array detection. International Letters of Chemistry, Physics and Astronomy 14:218-230. 8. Devendra Vaishnav, Janak Suthar, Tejas Oza, Gaurav Dave, Navin Sheth, Gaurav Sanghvi. 2014. A statistical approach for the enhanced production of thermostable alkaline protease showing detergent compatibility activity from Bacillus circulans. Biocatalysis and Biotransformation 32 (3): 151-160 Project

1. Seed money project supported by Saurashtra University 2. Sakshat, Ministry of Human Resource, Govt. of India. Ms. Payal Bhalodiya

1. To evaluate the efficacy of olanzapine analogues in schizophrenia using various experimental models” in International Journal of Pharmaceutical and Chemical Sciences in Oct-Dec 2012. 2. Evaluation of antiasthmatic activity of dried whole plant extract of Leucas aspera using various experimental animal models” in International Journal of Phytopharmacology in 2012 3. Preclinical evaluation of antiurolithiatic activity of Swertia chirata stems” in International Research Journal of Pharmacy in 2012. 4. Evaluation of cardiotonic activity of Moringa oleifera roots” in International journal of phytopharmacology. 5. Evaluation of neuroprotective effect of Coriandrum sativum Linn. against ischemic – reperfusion insult in brain” in International journal of phytopharmacology.

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6. A Panoramic view pharmacognostic, pharmacological, nutritional, therapeutic and prophylactic values of Moringa olifera LAN” in International Journal of Pharmacy in 2012. 7. Comparative Review on Harmless Herbs with Allopathic Remedies As Anti-Hypertensive” in Research Journal of Pharmaceutical, Biological and Chemical Sciences in 2012. 8. A systemic review on challenges with currently available cardiotonics and their safer herbal alternatives used in India” in Int. Res. J. Pharm. App Sci, 2012. 9. Evaluation of bronchodilator and antianaphylactic activity of Myrica sapida” in Iranian Biomedical Journal, 12 (3); 191-196, July 2008. 10. In vitro antioxidant activity of Gymnosporia montana leaves” Indian Drugs, 46 (10); 40-43, Oct 2009.

Ms. Priya Patel

1. Optimization of the experimental parameters of FP micro particles for pulmonary delivery using a box behenken design, Journal of pharmacy and bioallied science,Priya Patel, Tejal Soni, Vaishali Thakkar, Tejal Gandhi. March 2012;S48-S49. 2. Herbal excipients: An emerging field as a penetrarion enhancers in transdermal drug delivery system,Priya Patel, Paresh Patel, International journal of pharmaceutics research and development,April 2012,Vol.4, 058-068. 3. Biodegradable Polymers-excipients for Injectable Drugs, Inventi Rapid: Novel Excipients,Priya Patel, Maulik Vachhani 2013(3):1-4, 2013. 4. Study of altered Disintegration Behaviour of Immediate release pain medication in different beverages., International journal of pharmaceutical Research Scohalor,Vol-2,Issue-4,Pg.333-338. 5. Priya Patel, Tejal Soni, Vaishali Thakkar, Tejal Gandhi Nanoparticle as An Emerging Tool in Pulmonary Drug Delivery System, Micro And Nanosystems, 2013, 5, 288-302. 6. Microspheres For Intranasal Delivery System: As Review, Koyani V, Dedakia A.,Matholiya C., Patel P. Bioinfo Drug Targets, Vol 2 (1).Dec. 2013. 7. Smart Polymers: Innovative Drug Delivery System, World Journal Of Pharmacy And Pharmaceutical Sciences, 2014,Vol.3 (3) 520-528. 8. Formulation and Evaluation of Self Micro Emulsifying Drug Delivery System of Nimesulide, Priya Patel, Paresh Patel, Inventi Rapid: NDDS Vol. 2014, Issue 2 9. Study the amino acid behaviour in chitosan containing spray dried Powder for pulmonary drug delivery ,IJPRBS, 2014; Volume 3(2): 360-369 10. Analytical method development and validation forSimultaneous estimation of ambroxol,Chlorpheniramine maleate and phenylephrine hcl in Bulk and liquid dosage form by RP- HPLC method, Hina Bagada, Hitesh Panchal, Priya Patel , Aashka Jani, world journal of pharmacy and pharmaceutical sciences, Volume 3, issue 5, 1458-1467.

Book 1. “Nanoparticle for pulmonary drug delivery system” in Lambert Publishing House, Germany.ISBN NO.: 9783659417337(23/06/2013) 2. Book on “Skin Whitening” in Lambert Publishing House, Germany. ISBN 978-3-659-44399- 2(17/08/2013

Mr. Kashyap Thummar 1. Tank, M., Thumar, K., & Tanna, R. (2012). Method Development And Validation For Simultaneous Estimation Of Cefixime Trihydrate And Dicloxacillin Sodium In Combined Dosage Form By High Performance Thin Layer Chromatography. Inventi Impact: Pharm Analysis & Quality Assur.

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2. Bhatia, L., Thumar, K., & Tanna, R. (2012). Determination Of Adulteration Of Anti Obesity Drug In Indian Herbal Medicinal Product: Development And Validation Of Analytical Method. Inventi Impact: Pharm Ana & Qual Assur. 3. Gosai, M., Tanna, R., Thumar, K., & Chikhalia, J. (2012a). Development and Validation of First Order Derivative Spectrophotometric Method for Simultaneous Estimation of Metoprolol Succinate and Clopidogrel Bisulphate in Tablet Dosage Form. Inventi Impact: Pharm Ana & Qual Assur. 4. Gosai, M., Tanna, R., Thumar, K., & Chikhalia, J. (2012b). Method Development And Validation For Simultaneous Estimation Of Metoprolol Succinate And Clopidogrel Bisulphate In Tablet Dosage Form By High Performance Thin Layer Chromatography. Inventi Rapid: Pharm Ana & Qual Assur. 5. Gosai, M., Tanna, R., Thumar, K., & Chikhalia, J. (2012c). Rp-Hplc Method For Simultaneous Estimation Of Metoprolol Succinate And Clopidogrel Bisulphate From Tablet Dosage. Inventi Rapid: Pharm Ana & Qual Assur. 6. Patel, R., Tanna, R., & Thumar, K. (2012). Hptlc Method For Simultaneous Estimation Of Ibuprofen And Famotidine From Tablet Dosage Form. Inventi Rapid: Pharm Ana & Qual Assur. 7. Raval, M. K., Chikhalia, J. M., Gosai, M. B., & Thumar, K. (2012). Method Development And Validation For Simultaneous Estimation Of Metoprolol Succinate And Olmesartan Medoxomil In Tablet Dosage Form By High Performance Thin Layer Chromatography. Inventi Rapid: Pharm Analysis & Quality Assur. 8. Raval, M. K., Chikhalia, J. M., Gosai, M. B., & Thumar, K. N. (2012). Method Development and Validation for Simultaneous Estimation of Metoprolol Succinate and Olmesartan Medoxomil in Tablet Dosage Form by RP-HPLC. Inventi Rapid: Pharm Ana & Qual Assur(3). 9. Kher, M., Tank, M., Thumar, K., Sheth, N., & Kher, G. (2013). Development and Validation of First Order Derivative Spectrophotometric Method for Simultaneous Estimation of Cefixime Trihydrate and Dicloxacillin Sodium in Combined Tablet Dosage Form. Inventi Rapid: Pharm Analysis & Quality Assurance.

How convincing is the rationale/ significance/expected contribution of the project

Theoretically

 The proposed project is aimed to develop the state of art facility in the university and department to cater the need of surrounding Pharmaceutical industries. Moreover, it is aimed to give benefit to the real working hands, students of the university and departments to develop their skills to get more and more employment opportunity.  Expansion and modernization of existing infrastructure for PG & Research Work (viz. Laboratories, Library, Networking, Smart classrooms) and creation of a centralized computing and instrumentation facility with sophisticated equipments relevant to growth of different pharmaceutical areas. From the point of view of solution of real world problems

 Overall growth of Healthcare systems in Gujarat  Opportunity for students to get better employment after quality education  Research Background will be boost up in Gujarat  Development of Entrepreneurship skills amongst the people of Gujarat  Education system particularly pharmacy education of Gujarat will improve  National and International students will come to Gujarat to take Education in healthcare

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 More amount of patents will be granted from Gujarat  More MOUs will be generated with International Pharmaceutical Companies  Bridging the gap between industry and academia by Public Private Partnership

From the point of view of state importance

 Gujarat's pharmaceutical journey began in the early twentieth century, with the establishment of India's second oldest drug companies, the Alembic Chemicals Works Co Ltd, in Vadodara in 1907. The contribution of Gujarat to India’s pharmaceutical and health sectors can be gauged by the fact that this Western State, having only 4 per cent of the country’s population, accounts for more than 40 per cent of medicines manufactured in India.  Gujarat now has 3,637 licensed units engaged in this industry. Of these, nearly 800 are active in direct manufacturing of drugs. Only 20 per cent of these are medium or major manufacturers while 80 per cent are small-scale units. These include 384 units approved by the World Health Organisation’s Good Manufacturing Practice certification (WHO-GMP), and 29 units approved by the United States Food and Drug Administration (USFDA). Besides, there are other allopathic units (2,538), 712 (Ayurvedic), homoeopathic (14) and cosmetics (373).  Gujarat has over 1,100 formulation units and 400 bulk drug manufacturing units. The State’s share in national pharma production increased from 22 per cent in 2007-08 to 30 per cent in 2010-11. Various SMEs, research organizations and academic institutions have filed nearly 1,000 patents over the last five years.  Gujarat has also seen a 40 per cent growth in contract manufacturing as well as in API industry and 60 per cent in formulation. The pharmaceutical industry is concentrated in four clusters of Ahmedabad, Vadodara, Ankleshwar and Bhavnagar.  So, based on above data we can say that Gujarat — pharmacy to the nation is the Hub of Pharmaceutical Market of Country. The proposed project and support for its fulfilment will defiantly improve the position of Gujarat in INDIA. To cater the need of pharmaceutical industries in terms of skilled personals as well as to discover new molecules, research and infrastructure facility can be very much helpful. Such projects can bring the value of research at par and can bring Gujarat at the front of the country.

Credibility (experience and expertise) of persons involved: Specification of PIs and Co-PIs and their scholarship in the concerned area, credibility of other researchers involved

 The PI (Dr. Navin Sheth) and Co-PI (Dr. Mihir Raval; Dr. Nirav Patel) are the experienced persons as far as the academics and research field is concerned. Dr. Navin Sheth is having morethen 35 years of teaching and research experience. Dr. Navin Sheth has published over 154 publications in various National and International journals with total 5 projects in his credit.

 Dr. Mihir Raval is having morethen 11 years of teaching and research experience. He has published 41 publications in various National and International journals with total 4 projects in his credit.

 Dr. Nirav Patel is having morethen 10 years of teaching and research experience. He has published 34 publications in various National and International journals with total 2 projects in his credit.

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Other researchers are working in the following research area

Sr. Name of the Research Area No. Member 1 Dr. Navin Sheth  Traditional and herbal drug standardization 2 Dr. Mihir Raval  Crystallography, Particle engineering,

 Functionality improvement of API,

 Bioavailability enhancement

3 Dr. Sachin Parmar  Neuropharmacology and Toxicology 4 Dr. Nirav Patel  Nano technology & Targetted Drug Delivery for Cancer Research 5 Dr. Vaibhav Bhatt  Metagenoics, Meta-transciptomics exome sequensing and gene expression 6 Dr. Nasir Vadia  Development and Validation of Analytical Methods 7 Ms. Payal Bhalodiya  Metabolic Disorders, P’covigilance 8 Mr. Kashyap  Impurity Profiling Thummar 9 Ms. Priya Patel  Nano based drug delivery for lung targetting 10 Mr. Devendra  Novel Concepts of Biotechnology like Protein Crystallization, Vaishnav Fermentation Technology, Enzyme technology, SNPs Analysis 11 Ms. Heena Bagda  Bioanalytical Method Development 12 Ms. Krishna Koradia  Nanocrystallization and Solubility/Bioavailability improvement

Definition and significance/ value of research outputs/deliverables -reports/papers, product/ patent; software/translation to state/national policy framework.

 provide a strong evidence base to support the continued surrounding industries, academic sector and research centers

 improve the quality of learning-reporting about research outcomes to Government, the public and other organisations

 strengthen policy and strategy of drug development

 development and maintain a longer term relationship of academia-industry for new developments and patents generation

 improve communication with researchers and Research Organisations (ROs), offering new opportunities to explore how best to capture the results of research funding

 engage and collaborate with the business, government and pharmaceutical industries

 Strengthening of drug discovery processes and research orientation of students and improvement of employability.

Clarity of aims, objectives and research questions

 Drug development involves clinical and preclinical evaluations of obtained compound in animals and humans. Formulation development is required at various stages during drug development. Drugs are rarely administered alone. Incorporation of the drug into a formulation provides various

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advantages like ease of handling, ease of administration, better stability or better bioavailability. Different stages of clinical trials require different formulations. Preclinical stage is performed in animals and requires simple liquid formulations that can be easily administered to animals.

 A study of molecules derived from plant and synthetic sources needs again measurements in blood after administration. These requires to develop sophisticated analytical and Bioanalytical techniques, cell line evaluations, biotechnological and microbiological evaluations, etc.

 Aim of the proposed project is to establish the “Center of Excellence for Drug Development Technology” which can cater all the needs of research, fulfil the learning objectives and skill development is students and researchers. It is also aimed to cater the need of pharmaceutical industries by collobrative projects and patents.

 Objectives  To develop infrastructural facility with the instruments, equipments, analytical facility, research and cell line laboratory.  To develop characterization facility for examining products and samples  To develop animal house facility for a successful preclinical work  To generate industry-academic relation by MoUs and research collobrations  To utilize the research outcome for generating patents and publications

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Methodology - innovativeness/originality and soundness/rigour

 Quality of research design, appropriateness of methodology, and technical quality  Selection of molecules for the study  Awareness/selection of steps of work that is methodologically related  Development of analytical methods  Careful experimental work, reproducibility and reporting  Clear description of data, including accurate tables and figures  Quality and appropriateness of analyses (statistical and qualitative)  Sufficient investment in evaluating the consequences of interventions of industries/R&D sector  Careful evaluation of strengths and limitations  Use of output in terms of patents, publications, revenue generation

Definition and significance/value of Concrete outcomes – including

 Providing research support in terms of MoUs, collaborative projects

 A healthy academia-industry tie up for employability

 improve communication with researchers and Research Organisations (ROs), offering new opportunities to explore how best to capture the results of research funding

 Strengthening of drug discovery processes and research orientation of students and improvement of employability.

 More PhD candidates will be generated with prime research

 Product development, pilot studies and technology transfer process for scalability

 Development of patents for India and other countries

Inter-disciplinary/multi-disciplinary orientation and multi-institution networking

 The project is aimed to develop a facility to go for collobrative work with other departments of University, pharmaceutical industries and research centers. This collobrations will open up new pathway of drug development, new researches and ultimately a research environment/productivity will generate.

Anticipated Outcome (s) of the proposal • Societal benefit Proposed project will enhance employability of candidates of pharmaceutical field. Skill development will helpful the researchers for shaping their carrier in better way. • Economic Benefit New research and collobrations will bring economical benefit to the university in terms of revenue generation by patents sharing, technology transfer, training to the industry persons, contract work, etc. • New Knowledge Creation Drug development process will empower the clinical, preclinical and Preformulation processes in order to have more skillfulness to the candidates and more research outputs

Research and Innovation culture creation among affiliated colleges It can cater all the needs of research, fulfil the learning objectives and skill development is students and researchers of surrounding institutions. Training to the students will creat research ideas and workin skill.

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Annexure: 10

Research Proposal

Technologies for Affordable Healthcare

Submitted to

Knowledge Consortium of Gujarat

Pragna Puram Campus, Navrangpura

Ahmedabad - 380015

Under RUSA Scheme

Sardar Patel University

Centre for Interdisciplinary Studies in Science and Technology (CISST)

Vallabh Vidyanagar 388120

Gujarat

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Technologies for Affordable Healthcare

Summary: Recent technological advances led by biotechnological and genomics sciences have added numerous newer drugs, diagnostics and vaccines to our pharmacy repertoire. There have been more than 150 proteins and antibody based newer therapeutics, more than 300 monoclonal and DNA based diagnostics available in Indian market. However, barring about 10 of protein drugs, all other therapeutics and all of diagnostics are imported in India. It is now time that we need to enable Indian companies, both small and large, to manufacture these high end healthcare products and make them available to Indian market and export them also to rest of the world. There are also newer “smart formulations” of existing chemical drugs which are convenient to patients and increase therapeutic compliance. Such formulations are produced by larger Indian companies and available in market but at higher cost. Technologies for manufacturing these “smarter formulations” (controlled release formulations, sustained released formulations, drug patches etc.) have not reached SMEs (small and medium enterprises) and therefore these formulations remained high priced and have not penetrated public healthcare systems, where by most of the general public is deprived of such newer drugs and “smarter formulations” of existing drugs.

SPU as a part of CISST, initiated a project with the help of FDCA of Gujarat and Gujarat Medical Services Corporation Ltd. (GMSC) which procures medicines for civil public healthcare system. In this project we identified out of EDL (Essential Drug List) of GMSC about 20 drugs that are available as “smarter formulations” in free market but not procured by public healthcare primarily because SMEs that supply drugs to public system are technologically deprived to manufacture this type of formulations. Out of these 20 formulations we have developed and tested four formulations which in due course will be made available to SMEs at no cost and SMEs will be trained to manufacture these formulations that will technologically upgrade and enable SMEs and make benefits available and affordable to general public using public healthcare system.

With this project we will replicate this model of empowering SMEs for modern healthcare technologies and make them available to poorer segment of our society.

Introduction

India as a destination for Life Science Research has not reached its potential because Life Science commercial Research needs (a) High end knowledge (b) International networks and entrepreneurship (c) Sunk costs on hi-tech equipment. It is not like Body shopping or IT code. The little progress there has largely been in Bangalore, which started two decades ago. Yet potential tapped is less than the proverbial tip of the iceberg. In Life Science,

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financial support is the norm as the individual can only bring talent. In India, this Research is only done in State Institutions where International entrepreneurship and Commercial Research skills are not in existence.

Gujarat is being referred to as the hub of Pharmaceutical industry in India in the background of a large number of chemical industries developed at various sites of GIDC like Nandesaari, Ankleshwar, Vapi, etc, supported by a strong base of teaching and research in Life Sciences, Chemistry, Computer Application provided by several universities. Sardar Patel University is premier university among them.

By aggressively competing for various developmental schemes of the government and by support from philanthropists, the University has established strong Science Departments like Departments of Biosciences (Microbiology, Biochemistry, Biotechnology, Zoology, Botany), Chemistry, Physics, Electronics, Computer Science and Technology (including Bioinformatics), Materials Science (including Nano Science and Nano Technology), Home Science, Mathematics, Statistics and an infant Department of Pharmaceutical Science besides departments in Humanities, Social Sciences, Economics, Business Studies and Management. The detailed strengths of SPU is given in Annexure-I.

Translational Research is the acknowledged missing link in India’s Innovation System. Translation Research is a ‘lab to market’ focus, using proven elements. Biotechnology is today A Global knowhow business; a relay race, of building on proven elements and combing different, complementary strengths. Affordable Heath Platforms follow the Health World Concept encompasses the academic, entrepreneurial and other players in the health sector to strongly collaborative efforts, and the goals are to develop into a world class hub in ‘connected health’.

Affordable Healthcare can be achieved using the biotechnology as well as with the help of pharmaceutical technology

Biotech in Medicine and Affordable Health:

o Controlled- and sustained- release formulations o Protein and antibody based therapeutics o Biomarkers for various like diabetes, cancer etc. o DNA based and monoclonal antibody based diagnostics o Analytical diagnostics for drug‐abuse, hormones, pharmaceuticals

Since past many years, Sardar Patel University is working in association with Indian Drugs Manufacturing Association (IDMA) for technology transfer to Micro, Small and Medium Enterprises (MSME). Multinational Companies are manufacturing new drug delivery

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system due to the availability of newer technologies and expertise available. The benefit of this cannot be seen in the healthcare system as many of these technologies are not available to the common man due to the cost of the therapy. There is a need for providing these newer technologies for affordable healthcare. One such example is of making available the sustained release formulations of essential medicines which would cut down the need of frequent medications.

Looking at the need of affordable healthcare, it has been planned to carry out development of new technologies at the laboratory level using the expertise available at SPU and to translate the same to MSME for making it available to the society and to achieve affordable healthcare system

Scope and significance of the work

This is a project in which identified health related technologies are being adapted and used for Indian population. The scope of this work is to understand these technologies, simplify them when necessary, train and enable MSME to manufacture these products so that they are available to Indian customers at reasonable cost.

This project is about TECHNOLOGY ADAPTATION AND TECHNOLOGY TRANSFER.

 Promotion of Translation Research- Commercialisation of Academic Research  Access to World Class Knowledge for teaching Faculty and Students  Knowhow in Translational Research  Enables adapt products and technologies generated  Create an entrepreneurial centre that can stand on its own feet in 3 years  Elevation of SPU in faculty training, Programmes and Courses, Laboratories,  Setting up and establishing a research base for translation purpose  Establishing and operating a mutual beneficial liaison between the academia and industry partners  Brain pool of researchers trained with entrepreneur and revenue generating skills  Making available affordable and cheap technologies for disease diagnostics and cure

Objectives of the study

. To ensure the communication/crosstalk between the science and industry/health care providers.

. Builds a dynamic innovation process and infrastructure of multi-disciplinary RDI (open innovation, testing platforms)

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. Builds a strong RDI project portfolio to attract funding (thematic issues and priorities, spearhead projects, large research programs)

. Builds a strategic cooperation with global networks (innovation networks, joint projects, transnational testing platforms, mobility programs).

Methodology adapted

Based on the available list of Essential Medicines, Diagnostics and surgical Items provided by Gujarat Medical Services Corporation Ltd., Gandhinagar, Gujarat some 20 drugs which are widely in use, have been screened for developing sustained release formulations

The technology that would be developed at the laboratory level would then be provided to MSME for large scale production to be made available in the market at an affordable rate

Currently work has been started on four drugs namely Diclofenac Sodium (Anti- inflammatory drug), Pantoprazole (Anti-hyperacidity drug), Metformin (Anti-diabetic drug) and Doxycycline (Antibiotic)

Plan of the project in brief

Activities 1 Year 2 Year 3 Year

Month-wise 3 6 9 12 3 6 9 12 3 6 9 12 Recruitment of Manpower

Construction of Building

Procurement of Equipment and setting up of the Computational facility

Identification of research knowhow for translational purpose Academic activities such as Students and Faculty Exchange, Short term/Cert courses/Training Programs Services to users and stakeholders

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Broad requirements

1) Financial resources, financial plan and financial sustainability: fund availability, avoidance of duplication, and plan for financial sustainability/ raising resources

Details Amount Total (Rs.) Recurring Expenditure Manpower 1,00,00,000 2,51,00,000 (40%) Working expenses 51,00,000 Contingencies 1,00,00,000 Non-recurring Major equipments 3,00,00,000 3,79,00,000 Expenditure (60%) Minor equipments 79,00,000 Infrastructure Setting up of 70,00,000 (10% of the total Laboratory Project amount)

2) Manpower augmentation/ recruitment or engagement of highly qualified researchers- wherever applicable

Designation No/s Research Associates 05 Junior Research Fellow 20 Research Assistant 05

3) Laboratory enhancement: Equipments intended to be procured (future projection): i) Genome Sequencer ii) GC-MS iii) Microwave synthesizer with multi-reactor facility and variable pressure iv) CD Spectrophotometer v) Super critical fluid extraction system vi) CCCL + Software vii) TEM or MALDI-TOF viii) Minor equipments and related research infrastructure

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Possible Impact of the work

Societal benefit: Brain pool of researchers trained with entrepreneur and revenue generating skills; Making available affordable and cheap technologies for disease diagnostics and public health care

Economic Benefit: Establishing and operating a mutual beneficial liaison between the academia and industry partners and technological empowering of SMEs

New Knowledge Creation: Setting up and establishing a research base for translation purpose

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Annexure: 11 Proposal to Setting up

Incubation Center and Innovation Hub for Social Sciences and Humanities

(As per the Guidelines Provided)

At

Sardar Patel University

Vallabh Vidyanagar

Submitted to

Knowledge Consortium of Gujarat (KCG)

Department of Education

Government of Gujarat

December 2015

Submitted by

Sardar Patel University

Vallabh Vidyanagar

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About Sardar Patel University

The Sardar Patel University was founded on 31st October 1955, the Sardar Patel Jayanti Day, and a new star, named after, “the Iron man of India”, was born on the academic horizon of the country. The distinctive educational township of Vallabh Vidyanagar was established with the objective of accelerating the process of regeneration of villages by applications of modern science, technology including art to rural requirements. Vallabh Vidyanagar today hums with activities relating to learning and research and in addition to that industrial, commerce and trading to the public, private and co-operative sectors have blossomed in adjoining areas since long. The history of university touches the very core of freedom struggle and contribution of Sardar Patel in major unification of princely states and welfare of the farmers through constructive efforts. Sardar Patel University is story of dynamic development in almost all the dimensions of higher education. University is well in tune with the present needs and envisioning probable future. University started relevant courses whenever required with smooth efforts with the help of teaching faculties. The research records of the university also speak that university attended certain level of research including vital innovation practices.

About Vallabh Vidyanagar

Vallabh Vidyanagar is known as the campus committed to education with purpose. It has made its distinct identity in education sector in the last sixty years. Its lush green, peaceful ambience and pollution free climate have attracted many from various corners of the globe. Presently, it caters to the educational need of nearly 40,000 plus students across various disciplines. The town has all the amenities and facilities to evolve and expand quality life amongst the students. The town is a synthesis of varied cultures from across the world thereby fostering an environment of creativity among the students. Today the campus has compounded in strength and consolidated itself to take on the challenges of the emerging future.

Vallabh Vidyanagar is a university township just 5 km away from the Anand Railway station (The milk city of India) on Ahmedabad – Mumbai railway route. The nearby airports are

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Vadodara and Ahmedabad, which are 45 km and 90 km away respectively, from Vallabh Vidyanagar.

Vision of Sardar Patel University

Sardar Patel University envisages blossoming of human potential through:

 Nurturing of talent, skill, and scientific temper.  Creation of knowledge.  Incubation of wisdom.  Sustenance of blithesome spirit.

Mission of Sardar Patel University

Regeneration of rural Indian life with the application of the study and research in all the disciplines of knowledge in tune with the modern global developments.

Goals of Sardar Patel University

 To serve the rural population by providing them with access to higher education.  To continually explore new frontiers in the areas of Science and Technology.  To constantly set and reach new levels of achievement in research in areas within Humanities and Social Science.  To continue to focus on thrust areas in all the disciplines through indigenous research and collaborative ventures at the international level.  To become academically vibrant and financially sound institution of international standard.

Motto of Sardar Patel University

WE STRIVE FOR EXCELLENCE, FOR EXCELLENCE MATTERS

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PART – A

1. Outcome and Focus Area

The function of social sciences is to create and communicate knowledge that help in promoting efficacy of the people engaged in variety of activities for the social good. It is also a felt need that social sciences should undertake futuristic studies with a vision that help in solving the problems and issues of socio economic and cultural nature for better democratic life in the society. The proposed centre will also make linkages with other institutions for fulfilling the purpose of the proposed centre.

In order to bridge the gap between academic institutions and the society, the center will take a lead in creating social entrepreneurship, innovation and quality research oriented academic environment concentrated to integrated human development.

The proposed incubation center in social sciences aims to coordinate, synergize and leverage the various strands of excellence nurturing innovation and entrepreneurship in domains of Social Sciences, Languages, Literature and Cultural studies.

Outcomes of Proposed Center

 Innovative academic initiatives

 Generate research consultancy

 Nurture and build ideas of social ventures through social entrepreneurship

 Centralize Computational and Network Facility to promote research

 Integrated learning through research community

 Develop alternative methods of student centric teaching

 Devices new interdisciplinary and multidisciplinary courses at Undergraduate and Postgraduate level.

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 Design Teaching-learning materials needed for the new approach and produce necessary digital resources from research conducted by faculty members with the help of students

 Strengthen Institutional digital repository of Sardar Patel University by in-house digital publications.

 Enhance the employability of humanities and social science students

 Develop a competitive skills of humanities and social science students

The major components of the scope of the proposed center will be as follow

I. Research in Humanities, Social Science, Languages and Literature

II. Innovative Teaching, Learning and Evaluation

III. Implement best practices of extension activities

Research in Humanities, Social Science, Languages and Literature

 Integration of Research and Incubation of Ideas

 Provide financial support for interdisciplinary &multidisciplinary projects in Learning, Teaching, Testing and Research

 Develop mechanism and system to evaluate feasibility of various innovative ideas in terms of research proposal and implementation with replication for better generalization

 Provides a repository of notable current work in interdisciplinary studies in India

 Promote predictive research studies in emerging issues having massive social impact

 Conduct Qualitative research in the field of social sciences, languages, literature and culture.

 Analyze feasibility of social venture by generating, nurturing and supporting social entrepreneurship

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Facilitate Innovative Teaching, Learning and Evaluation

 To develop and conduct training programmes for students, faculty members and paraprofessionals required to implement the interdisciplinary approach and other suitable learner-centric methods

 To organize capacity building programmes for students, faculty and supporting staff to promote the cause of holistic, integrate educational methodologies

 To address emerging challenges in field of humanities and social sciences in teaching, learning and evaluation process

 Nurture innovative and research based teaching and learning

 Conduct various local problem based research projects with the help of students as part of their curriculum.

 Design and implement field based investigation, action research, and live projects in the curriculum of social science subjects.

 To generate meaningful innovative practices in curriculum enrichment and recent pedagogy for teaching the same.

 Help students to acquire skills as translators, copy editor, script writers, copy writers for advertisement, designers of book, choreographers, film editors, art gallery managers, curators, art critics, theatre critics, radio announcer, news reader, journalist, novelist, event manager and various such skills.

Link University with Society and Industry

 Proposed Incubation and Innovation cent will acts as the nodal agency for networking with other interdisciplinary study centers of the university as well as outside the university.

 Generate and facilitate interactions with other Educational Institutes, Government Organizations, NGOs, and Professional, practitioner and corporate sector.

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 To organize different non-curricular activities to generate more interest and relevance of social sciences among students and faculty members.

 Implement concept of integrated learning to open up various opportunities and prospects for career development.

 Establish link between future learning trend and extension activities as a mean of practical learning in a natural way.

 To harness the ingenuity and community of young Indian who values quality and aspires scale greater heights.

 To collaborate with different agencies of society and nearby industries through research projects, student’s practical assignments and live projects

2. Scalability and Sustainability of the Project Proposed

The Sardar Patel University has 26 postgraduate departments in sciences, social sciences, humanities, and business administration and more than 80 affiliated colleges catering to various disciplines. Recently with the efforts of Government of Gujarat, 39 more colleges added to affiliation of Sardar Patel University.

The thrust of the proposed center is to generate, nurture and implement innovative ideas through research that ultimately enhance the employability of students and research based consultancy projects. Hence, the proposed center aims and objectives of the center will be scaled up phase wise

Phase-I: General and build innovative academic culture in the domain of social sciences and humanities

Phase-II: Integrate all disciplines related to Social Science, Language, Literature and Performing Arts

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Phase-III

Networking with external world (Other NGOs, Public Utility Services, Social Sector, and Industry). Understand problems faced by society in the domain of social science and humanities and conduct research on it.

Phase-IV

Integrate research and teaching with the help of students community and society

Phase-V

New System of Learning through interaction and consultancy projects from various sectors of society with the integrated efforts of faculty members and students. Prepare structure and policy to promote consultancy by faculty members of postgraduate department of University. Provide all necessary support and facility to those teachers who are ready to do consultancy projects. Center will help teachers to collaborate with different external agencies and organization to encourage consultancy among faculty members.

Sustainability of this center will be ensured by innovation based eco system and enhancing the relevance of social sciences in external world. The center will pursue tobuild and sharpen the learning curve of human resources of Sardar Patel University in terms of consultancy projects and policy guideline assignments that bring sustainability of this center.

3. Prioritization on Area of Research done by the state

Incubation centre by adopting an integrated historical, social economical contextual framework will explores in chronological order the development of six pairs of inter-disciplines such as

(i) Genetic biology and sociology,

(ii) Humanities and communication,

(iii) Social relations and operations research

(iv) Cognitive science and recent innovation and trends

(v) Cultural studies with varieties of contacts

(vi) Biosciences and literacy studies.

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(vii) Literary studies, recent trends and human centered approach

With such inter disciplinary frame work, the topics in social sciences and humanities

(i) Comparative literature: study of Indian literature in comparison with world literature. – Gujarati, Hindi, English and other languages.

(ii) Rural Development: Policy, Programmes and Prospects:- Economics, Sociology, Public administration, Management, Education and Political sciences.

(iii) Industrial Development in India: Economics, Sociology, Managerial, Psychology.

(iv) Indian Diaspora Community in foreign countries: Sociology, Political science, Economic and literature.

(v) Ecology and Environment: Conditions, Problems and Programmes:- Sociology, Bio-sciences, Economics, Public administration, Social work.

(vi) Human Development: Policy, Programmes, Impact,Economics, Sociology, Psychology, Management.

(vii) Panchayati Raj Institutions: Policy, Performance, Problems and Impact:- Political science, Sociology, Rural studies.

(viii) Weaker sections and Human Rights: Sociology, Political sciences, Public administration, Social work and Education psychology.

(ix) Literature and Society: Gujarati, English, Hindi, and Sociology.

(x) Historical case studies: History, Sociology, Anthropology

Following is the detailed discipline wise list of areas in which our university is doing research and further proposed to extend the research.

History

 Historical Case Studies

 Environment Histories

 Tribal/Adivasi Histories

 Intellectual Histories

 Maritime Histories

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 Concept of Modernists/Histories of Modernists

 18th Century India V/s India in next century

 Post Modernism and Historic view

 Violence and historic roots and resolutions

Political Science

 International Relations

 PRIS: Performance, Problems and Prospects

 Dynamics of Indian Politics

 Electoral Politics

 Indian Freedom struggle and Politics

Hindi

 Tulnatmak Sahitya (Conparative Literature)

 Natak Evam Rangmanch (Drama and Stage performance)

 Anuvad (Translation)

 Lok Sahitya (Traditional literature)

 BhashaVigyan (Language Science)

Gujarati

 Folk lore and folk literature: Motif Study

 Comparative literature: World literature and Indian literature

 Linguistic and Stylistics

 Art of film affrication

 Word net

 Sociology and literature: Literature and Society

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Sanskrit

 Sanskrit language and recent progress

 Indian Philosophy and Psychology in Sanskrit classic literature

 Political economy reflected in Sanskrit literature

 Socio-religions movements back by Sanskrit shastras

 Indian knowledge system and Sanskrit

English

 Culture studies and Media

 Postcolonial Studies

 Indian language literature and literature in translation

 Translation studies

 Status, Conditions and Problems of Aged (old-aged) in India

 Sociological approach in English literature

 Modern English literature

 Hermeneutics and literature

Sociology and Social Work

 Diasporas’ and Cultural studies

 Human Rights, Social Defense and Social justice

 Atrocities on women and other weaker sections

 Rapid Rural Appraisal, Social Political Planning, Developmental studies, Environmental studies.

 P.R. Is, Political Partition and Performance studies

 Role of NGOs in Society

 Conscious citizenship on voluntary basis

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Psychology

 Motivation studies

 Industrial and organizational Behaviour

 Clinical and Counseling

 Behavioral Perspective as base of psychology

 Behavioral Problems and Measurement

Economics

 Rural Development

 Public Policy and Public Welfare

 Agriculture Economics

 Environmental Economics

 Human Development including District and State Human Development study

Education

 Information and Communication Technology (ICT) integrated teaching learning

 Indian Psychology, Philosophy and advanced pedagogy

 Education Policy and programme related studies

 Introduction to Indian psychology and philosophy as reforms in approach

 Education for empowerment

 Environmental education, human right education and citizenship education

Commerce and Business Management

 Issues and challenges of Medium and Small Scale Industries

 Goods and Service Tax as a part of Tax reforms

 Role of Services in Rural Development

 International Financial Reporting Standard (IFRS)

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 Corporate Governance

 Consumerism and Consumer Empowerment and Consumer Behaviour

 Business Analytics and System Management

 Digital marketing and recent trends

4. Quality of Institution (NAAC Grade) and Faculty undertaking the Research

Sardar Patel University was among the first in Gujarat to volunteer for assessment and accreditation by the NAAC (National Assessment and Accreditation Council), Bangalore. The University was awarded B grade (CGPA-2.83) in September 2011. 5. Accountability of the Project

The centre will conceptualize, organize, execute and evaluate activities undertaken by the incubation centre and innovation hub. It will be the freedom of the organization to constitute a committee for the various segments like guidelines for innovative proposals, interdisciplinary and multidisciplinary teams, to generate effective procedures that expedite the work of the said centre.

The administration and governance is expected to be autonomous that incorporate both power and responsibilities. The annual report will be prepared by the centre in a published form with full indication of works done in and through the centre. Every year there will be two meetings with the chairmanship of honourable vice chancellor, director, assistant director and too invited experts.

Good governance forms necessary ingredient for any effective academic institutions. The broad framework of the proposed center will be given as follow.

1. Honourable Vice Chancellor of the University will be the Chairman of the center.

2. Honourable Vice Chancellor will appoint Director of the center with the help of expert committee of professors for the duration of three years.

3. Honourable Vice Chancellor will also appoint two coordinators, one from social sciences and one from languages, literature and cultural studies for the duration of three years.

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4. One project officer and research assistant cum computer operator can be appointed on contract basis.

5. Supportive staff including two clerks and two peons will be appointed on contract basis.

6. The proposed Incubation and Innovation center will operate as autonomous entity of the university with required academic autonomy and flexibility.

7. Proper accounts and financial records will be maintained and audited on a yearly basis.

8. The center will prepare Annual Project Planning and Annual Report of its activities and work on mission mode basis.

9. Concern authority will be accountable to review the result and progress towards set standards and goals.

10. At every six months (half yearly) review meetings will be called and minutes of the same will documented.

11. Two representatives from each postgraduate department of humanities including social sciences, languages, education, literature, commerce and management will work as link between this center and respective post graduate departments.

12. Center will inform about its proposed annual projects and activities to each postgraduate department and other concerned departments through various mode of communication.

13. Separate link will be created for this center on the website www.spuvvn.edu

14. The center will work in close coordination of Administration, Departments, different cells, Students forum, surrounding institutions and government agencies

University is ready to do necessary Memorandum of Understanding (MOU) to propose establish Innovation and Incubation center with concerned state and central government agencies.

6. Phase/implementation millstones and plan of action for 2015-16 and 2016-2017

Plan of Action 2015-16: Ideation and building innovative campus

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 Core teams of different social scientists continuously interact and will identify issues, challenges and problem related to sciences.

 Review and research on emerging practices of social sciences by two core groups’ i. Social Sciences ii. Languages, Literature and Culture

 Study and document the best innovative practices in the field of social sciences by professionals, activists, industrialists, government machineries.

 Monthly interaction and dissemination of knowledge generated by innovative practices of the center among faculty members and students of social sciences.

 Organize Skills Enhancement workshop, Faculty Development Programmes that help to learn emerging issues, new research tools and technology and help to get consultancy projects

 Organize specialized workshop, Filed work Projects and Hands on Experience sessions for students and teachers

 General and evaluate feasibility of various ideas to convert them into research proposal or social venture

Plan of Action 2016-17: Strengthen the Learning curve through consultancy Projects

 Identify the possibilities and sources of consultancy projects

 Collaborate with external Government and Private agencies through consultancy projects

 Provide support and guidance to teachers for consultancy

 Strengthen the Academic-Industry link for better placement of students

 Involve students in consultancy projects for practical learning

 Integrate research projects and teaching-learning process

 Design and offer vocational skill based inter-disciplinary and multi- disciplinary undergraduate as well as postgraduate courses

7. Financial resources, Financial Plan and Financial sustainability

The proposed center will use existing infrastructure of the university and generate resources and facilities as per the proposed budget given as follow. It has been prepared as per prescribed financial norms.

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The proposed center expected to raise funds through research consultancy. The center will generate ideas of innovative and path breaking research and will get research projects from other funding agencies. Over period center strive to be self sustain and also leverage the financial and non financial resources of university.

Proposed budget of The Center

Sr. Expenditure Amount Proportion no. (Rs.) 1. Building of center 40,00,000 10%

2. Infrastructure 2,00,00,000 50% Furniture 75,00,000 Projectors, 2,00,000 Computers and Printers 3,00,000 Books Journals, 20,00,000 Internet facility 10,00,000 other equipments 10,00,000 Centralize Software 25,000,00 Centralize Database 25,00,000 Digital resources 30,00,000 3. Honorarium of center 1,00,000,00 40% director, two coordinators, project officers, research assistant and administrative and supportive staff and organization of 60,00,000 Conference, Seminars, Workshop, Symposium 4,00,000,00 Total

8. Quality improvement/gap filling projection in the form of Building of academic/research capacity of manpower (Students and teachers) and in the form of improvement of equipment/facilities

Sardar Patel University has treasure of well experienced and young talented teachers in all most all branches of knowledge. The proposed center will build innovative academic/research capacity of manpower (Students and teachers) and attempt to do following task for the same.

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 Directing young human talent towards meaningful creative perspective of life and practice.

 Provide conducive environment to sharing innovative ideas and transforming into action.

 Direct and design for the better academic pursuits inclining research

 Integrate Social Science, Languages, Literature and cultural studies that create cohesive academic work environment.

 Develop mechanism and system to convert innovative ideas into better academic practices, innovative teaching and general local issues based research studies.

 Create and provide an excellent academic culture that promotes productivity and enhances efficiency of both students and faculty members.

 The center will strive to match quantitative expansion of higher education with qualitative improvement.

 Center proposed to generate centralize facility of digital resources, computation software and multi-disciplinary publication.

9. Evidence/plan of academic-industry partnership

University has Academic-Industry Research Cell under which university used to conduct various activities to in collaboration with industries. Many postgraduate departments of social sciences do associate with many industrial set up. Further with the help of proposed center, academic industry partnership will be strengthen and capitalize.

10. Promotion of Innovation – Innovation/incubation hubs, supporting start up/entrepreneurs wherever Applicable

As mentioned in Phase wise implementation and plan of action for next two years, proposed center first pursue to build inter-disciplinary and multi-disciplinary based innovation culture. Proposed center will integrate all disciplines related to Social Science, Language, Literature and Performing Arts to generate innovative ideas from diversity and their integration.

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In order to understand need of society, center will do networking with external world (Other NGOs, Public Utility Services, Social Sector, and Industry). Understand problems faced by society in the domain of social science and humanities and conduct research on it.

At fourth phase of plan, the chief aim of the center is to Integrate research and teaching with help of students and society. Finally, new system of learning through interaction and innovation will be generated. Attempt will be made to get more consultancy projects from various sectors of society with the integrated efforts of faculty members and students. More linkage with society, research consultancy will generate practical learning and enhance the employability of students and provide sustainability to university.

11. Manpower augmentation/recruitment or engagement of highly qualified researchers – Wherever applicable

University will engage researchers and experts from internal sources and also take the help of experts in social sciences, humanities, Language, Literature and performing arts. Center will coordinate and capitalize present strengths and resources of Sardar Patel University such as

a. Community Science Center

b. Agro Economic Center

c. Bhaikaka Library and Information Science Center

d. Different Chairs established in Sardar Patel University with concerns of Humanities and Social Sciences

e. Corporate Bank Chair in Management

f. Campus Radio station

g. University Museum

h. Alumni Association of University and departments

i. Publication unit of Sardar Patel University (Journal of Sciences, Social Sciences, New Bulletin of Sardar Patel University)

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j. Women Empowerment Cell, Career Counseling Cell, Industry-Academic Cell of the University. k. Board of Study and Academic Counseling of respective discipline related to social science and humanities.

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PART-B

1. Existing body of research work in that area (fresh proposal not allowed) Fit and credibility of past work, past achievements of proposal center/concerned research team

Research is a very significant activity of the University. The University has a very active faculty committed to research and development. A great importance is attached to research, both as an activity and source for generating new knowledge. The University teachers and researchers are fully committed and dedicated to research.

Nonetheless, the nature of our mandate as a university entailed research going hand-in-hand with teaching since we came into existence in 1955 and has been a plus point with us winning recognition for us from the UGC, other agencies of the Governments of India and Gujarat State, and the NAAC time and again. Our mandate implies a perception of research as a problem- solving exercise similar to learning and testing aimed at uncovering what we need to know or have yet to know. We take research as a systematic and thorough process of learning something by means of an investigation which aims at making value addition to our existing store of knowledge.

New Research Projects Undertaken and Grant Received By the Teachers of Economic, Business Studies and Management Postgraduate Departments in 2010-2011

No. Departments No. of projects Amount 1. Business Studies 03 11,23,700/-

2. Economics 01 4,00,000/-

3 Business Administration (MBA) 01 4,60,000/-

Total 05 19,83,700/-

New Research Projects Undertaken and Grants Received by the Teachers of Postgraduate Departments in Social Sciences & Languages in 2011-12

No. Departments No. of projects Amount 1. Social Work (MSW) 03 5,21,200 2. Gujarati 03 6,39,000 Total 06 11,60,200

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New Research Projects Undertaken and Grants Received by the Teachers of Postgraduate Departments in Social Sciences & Languages in 2012-13

No. Departments No. of projects Amount 1. Education 01 446500.00

2. History 01 489500.00

3. MSW (Social Work) 07 1920000.00

4. Psychology 02 00.00

5. Sociology 01 802100.00

Total 12 3658100.00

Ongoing Research Projects Undertaken and Grants Received by the Teachers of Economic Sciences Postgraduate Departments in 2013-2014

No. Departments No. of projects Amount(`) 1. MBA 05 8354350.00

2. Economics 04 1240000.00

Total 09 9594350.00

Ongoing Research Projects Undertaken and Grants Received by the Teachers of Social Sciences Postgraduate Departments in 2013-2014 Sr Departments No. of projects Amount No. 1. History 01 489500.00

2. Social Work (MSW) 03 1676600.00

3. Education 01 446500.00

Total 05 2612600.00

Many postgraduate department such as Economic, Gujarati, Business Management, Business Studies (Commerce) got UGC’s special grant under Special Assistant Programme (SAP). Many departments are doing research at second or third phase of DRS under SAP.

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The proposed incubation center and innovation hub in Humanities, Social Science, and Languages will get benefit of existing research base and experience of university’s knowledgeable researchers.

2. How convincing is the rational/significance/expected contribution of the project/center Sardar Patel University always pursues to be Research University. University conducted the highest number of Minor and Major research projects of UGC and other funding agencies in the state of Gujarat. At Sardar Patel University, the highest number of Postgraduate Departments is having UGC-SAP Programme in the Gujarat state.

 Youngsters at this University have revolutionary ideas that need acceptance, support and assistant from system that will surely transform the University.

 Leverage robust infrastructure and image of the University.

 There is an ample amount of opportunities for consultancy.

 Our University can generate India’s largest foreign alumni association.

 We can build strong linkage with nearby GIDC by practically activating our Industry Linkage Cell.

 Model rural university in the country.

 We already have strong tie up with world class local as well as state level institute. Still we can strengthen this with strategic move.

 We can also develop our university as tourism destination.

 We can take the maximum advantage of Public private partnership as we are situated on the richest belt of NRIs.

 We can utilize the knowledge of experts and talented students with right planning and coordination.

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3. Credibility (experience and expertise) of persons involved – Specification of PIs and CO PIs and their scholarship in the concerned area, credibility of other research involved

University has many researchers and scholar academician; they all will be involved in the various proposed activities of the center. So far as governance of the center is concerned, the best suitable persons will be given responsibility on merit and performance basis.

4. Definition and significance/value of research outcome/deliverables – reports/papers, product/patent, software/translation to state/national policy framework

The proposed center will strive to generate following research outcomes

 Research based study material for teaching learning

 Provide directive and insightful suggestions for policy making to government in form of voluntary research reports

 Generate research based consultancy perspective and general financial resources through consultancy

 Generate and conceptualize research proposal on innovative contemporary issues to get more fund from various funding agencies

 Strengthen the institutional digital repository of university

 Publish books on inter-disciplinary and multi-disciplinary nature of study

 Promote, facilitate and nurture innovative ideas of students and faculty members and convert feasible ideas into successful business venture

5. Clarity of aims, objectives and research questions

Vision and Mission of proposed Incubation and Innovation center will idea about aims of the proposed center.

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Vision of Incubation and Innovation Center

 Exploring, Conceptualizing and practicing innovative ideas in the field of Social Sciences and Languages.

 Generating, Strengthening and capitalizing the innovative proneness and practices among faculty members and students for academic and related excellence in Humanities, Social Sciences and Arts.

Mission Statements of Incubation and Innovation Center

1. Develop a holistic outlook and approach that enable teachers, researcher and students to create knowledge for the future

2. To provide platform for discovering contemporary issues and problems of Humanities, Social sciences and Arts

3. Enhance relevance and competitiveness of social sciences, Culture, Languages, and literature.

4. To collect, design and envisage innovative ideas for enriching praxis of life in all its dimensions through well identified applied researches.

5. To help in ensuring rural development in perspectives of Social Sciences, Languages, Culture and literature

Objectives of Incubation and Innovation Center

1. To invite and appreciate rationally, the contemporary innovative practices in all dimensions of higher education.

2. To be a hub for greater dialogue between academic disciplines and much desired knowledge generation by this dialogue.

3. To encourage interaction and coordination between and among the departments of Social Sciences and humanities for developing innovative practices in teaching, learning, research and extension.

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4. To envisage the emerging needs of the society and providing a platform to initiate advanced researches with better identification that vitally helps in solving and resolving problems having core relation with social sciences and languages.

5. To provide platform for discovering contemporary issues and problems, and helping to find acceptable solutions for them.

6. To collaborate with government, non-government and local self government organizations for solving their problems in an intellectual and constructive ways.

7. To encourage innovative researcher to conduct applied research studies of interdisciplinary, multidisciplinary nature with full inclusion of local and global context.

8. To empower students and teachers for contributing to knowledge by acquiring, generating and disseminating processes.

9. To conduct evaluative studies about various developmental welfare programmes carried in Charotar region and extended to .

10. To develop data bank for region to enable local administration for enabling local administration for good governance.

It is need of the hours to bring out qualitative reforms in the field of Higher Education through socially relevant and innovative researches. In order to implement and develop Research and Innovation in the state of Gujarat among faculty members and students, persistent and well focused efforts are required. Sardar Patel University proposes to establish Incubation Center and Innovation Hub for Social Sciences and Humanities, keeping in mind problems presently faced by domains of Human centrality that is Social Sciences, Languages, Literature and culture related sub areas.

The time has come to think of the society 50 years from now

 What will it be like?

 How will it function?

 What will be its core values?

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 How will it shape itself and take charge of itself?

These are the research question in broad perspective as it covers all areas of social sciences, arts, performing arts, literature, languages.

6. Methodology – Innovativeness/originality and soundness/rigor

Systematic and strategic methodology will be followed with following features.

 Exploratory research design will be used in the first year of the center at the first phase of the proposed center.

 Interaction and brainstorming among faculty members in social sciences, humanities, language, literature and performing arts

 Identify need of the society; understand various problems and challenges of society

 Identify and diagnose skill gap among students

 Develop capacity of teachers to get consultancy projects and integrate their research with teaching-learning process

 Primary data based research will be conducted to check feasibility of innovative research ideas, consultancy possibilities, social entrepreneurship by students and teachers

 Build skills of students to increase their employability

 Integrated and well focused efforts to enhance the relevance of social sciences, Languages and Literature in society

7. Definition and significance/value of concrete outcomes-including

The center will encourage conducting more interdisciplinary, multidisciplinary and integrated cognitive science based doctorate and post doctorate research studies. Attempt will be made to convert doctorate work into scholar publication in high impact factor and h-indexed journal of social sciences. Focus of the center will be to address policy issues and real life problems to increase the relevance and values of social sciences related disciplines.

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8. Inter-disciplinary-multi-disciplinary orientation and multi-institution networking

All such innovative activities will be carry out with the help of two separate core groups

i. Sardar Patel University Intelligence – I: Social Sciences

a. Economics

b. Sociology

c. Anthropology

d. Political Science

e. Psychology

f. History and Anthropology

g. Education

h. Commerce (Business Studies)

i. Management

j. Rural Development and Agro Science

k. Library and Information Science

l. Home Sciences (including Human Development)

m. Media Studies and Journalism

n. Social Work and Human Resources Management (MSW and MHRM)

o. Communication and Media

p. Performing Arts and Fine arts

q. Community Radio center

r. Music

s. Computer Science

t. Philosophy

u. Neuroscience

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ii. Sardar Patel University Intelligence – II: Languages’, Literature and Culture

a. Hindi (Including drama)

b. Gujarati

c. Sanskrit

d. English

Center will collaborate with

 National Innovation Foundation - India

 Incubation Centers and Societies for Innovation & Development at institutions of national repute such as Indian Institute of Technology(IITs) and Indian Institute of Sciences (IISc)

 Center for Entrepreneurship Development (CED)

 Entrepreneurship Development Institute, Ahmedabad (EDI)

 Incubation Center of Indian Institute of Management Ahmedabad (IIMA)

 Gujarat Technology University (GTU) Innovation Counsel

 ICSSR sponsored Center for Social Studies at South Gujarat University, Surat

 Tribal Research Center and Rural Technology of Gujarat Vidyapith,

 Indian Institute of Rural Management (IRMA)

 National Dairy Development Board (NDDB)

 Anand Agriculture University

 Tribhovandas Foundation

 Vithal Udyognagar GIDC Association

 Vidyanagar Nature Club

 Indian Institute of Public Administration – Vallabh Vidyanagar Branch

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 Local chapters of All International Organizations such Rotary, Lions Club, JCI, Spikmacy etc.

 All other National, State and local organizations that help to achieve the set objectives of the center.

9. Anticipated Outcome (s) of the proposal

As presented in vision, mission and objectives of the proposed center, the primary focus of all proposed activities will be society. As the proposed center will include subjects of social sciences, one cannot think academic institutions in isolation of society. However at present there is huge gap between need of society and academic outcomes. The proposed center will associate with different sections of the society through research and academic endeavors. Center will also generate economic resources through research consultancy and financial resources from other funding agencies by conducting innovative user urgent research. Local area study based knowledge which will be interdisciplinary and multi-disciplinary in nature created and disseminated through scholar publication in journals, reports based on consultancy assignments, practical input based study materials for students, working papers, institutional repository on university’s website.

10. Research and Innovation culture creation among affiliated college

Students, management and faculty members of affiliated colleges will also be involved in the plan of action of proposed center and they will be given equal opportunity to be part of vision, mission and several projects under this proposed center.

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Proposed budget of The Center

Sr. Expenditure Amount Proportion no. (Rs.) 1. Building of center 40,00,000 10%

2. Infrastructure 2,00,00,000 50% Furniture 75,00,000 Projectors, 2,00,000 Computers and Printers 3,00,000 Books Journals, 20,00,000 Internet facility 10,00,000 other equipments 10,00,000 Centralize Software 25,000,00 Centralize Database 25,00,000 Digital resources 30,00,000 3. Honorarium of center 1,00,000,00 40% director, two coordinators, project officers, research assistant and administrative and supportive staff and organization of 60,00,000 Conference, Seminars, Workshop, Symposium 4,00,000,00 Total

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Annexure: 12 Research Centre in Area Studies of Charutar Region

Preface One of the premier academic and research institutions of higher education in Gujarat State, Sardar Patel University has been in the forefront in identifying areas in which innovation is needed since 1955, the year of its founding. Sardar Patel University is home to a rich tradition of teaching and research activities. Our scholars take an interdisciplinary approach to set and reach higher goals in disciplines that span from arts to engineering, and education to medicine. The mission of the University is the regeneration of rural Indian life with the application of the study and research in all the disciplines of knowledge in tune with the modern global developments. Strong support from the colleges and postgraduate Departments has allowed us to build both traditional and innovative programmes in recent years. We are driven by an urge to dig deeper, push further and to leverage our knowledge to enrich all human life in all we do.

Part-A: Theoretical Aspects

1. Outcome and Focus Area of research Proposal Outcome The research project will provide an excellent foundation for those who wish to expand their knowledge of area studies prior to working for N.G.O., national organization or in other professional capacities. Many of our events such as seminars, workshops etc will be made particularly dynamic by the cross fertilization of scholarly and creative agendas.

- Students will gain intercultural knowledge and competence that benefits them in this increasingly globalized word.

- New courses will be framed and taught initiatives taken for out-reach activities and forging academic linkages with the region - area study.

- Archives of Charutar will be established in the compass.

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- The Centre for Area studies will organize numerous events which expose the university as well as the community at large, the many issues and their solutions.

- Books, Research papers, journal will be published.

Focus Area of research Proposal We strive to build bridges between the disciplines of humanities and social science, university and society, scholars and people. Our area of research is the Area studies. It is an interdisciplinary study programme encompassing all disciplines within the Humanities and Social Sciences. The programme focuses on the study of Charutar region, for our university was established in rural settings in the heart of the Charutar belt in central Gujarat.

This project aims at focussing research on the richness of history, culture, social conventions, everyday life in sociological perspective; sociology of health and illness behaviour; modernity and urban process; problems of Non Residential Gujaratis (NRGs); democratic governance and government policies implications for quality of people of Charutar; environment and socio- culture; values and Charutar region; festival and the cultural heritage in Charutar; socio-psycho perspective on aging of people of Charutar; research into historical patterns in gender relations; indigenous communication system and modernity; work and leisure: transformation of leisure of people; the role of women in the development of future of Charutar; youth, culture and media; the apathy of youth toward current affairs; language teaching programme in rural area; psychological study of contemporary issues; the role of the media in shaping norms of social formation; socio-economic patterns of development; new word formation in modern Charutari dialect; form and functions of NGOs in the Charutar region; and working patterns of educational institutions, industries, health centres etc.

Thus project proposes to support both contemporary and historical research in the area of Charutar region.

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2. Scalability and Sustainability We are acutely aware of the fact that we will need to make our inquiry as systematic possible, exploring the area using approaches that are interdisciplinary and even multidisciplinary in their orientation. We wish to attain our central objective of mapping whatever is feasible and possible and help create authentic and reliable documentation by area study. A mentoring committee will keep eye on our work. We will get peer review by peer review teams for the scalability and sustainability of the project.

3. Prioritization on Area Research Done by the State and Why Charutar Region is an important part of the state of Gujarat as it gave to the country our first Deputy Prime Minister, Shri Sardar Vallabhbhai Patel, also recognized as the Iron Man of India, who unified the Princely state in the country after independence in the form of the Union of India as we know it today.

Professor (Dr) Mario Rutten and Professor (Dr) P J Patel (former Vice Chancellor, Sardar Patel University) conducted research on the Patidars of Charutar region in 2004-05 and presented its findings to an International Conference on Diaspora Studies in London in 2004-05. Incidentally, Professor (Dr) Mario Rutten was in Sardar Patel University on a research grant as a Research Professor in the Department of Sociology for a term. Research of non-resident Gujarati-Indians who belong to the Indian Diaspora in the west was conducted by Lord Bhikhu Parekh, Professor (Dr) Pravin Seth among others, and the findings of these research studies were presented at International Conferences hosted annually by the Centre for Diaspora Studies, Sardar Patel University, Vallabh Vidyanagar (2005-2013) and Centre for Diaspora and Cultural Studies, Hemchandracharya North Gujarat University, Patan (2005-09). The presentations were made of studied papers on area studies exploring important towns, works authors, economists etc not only in the state of Gujarat and India but also from host countries where Indian Diaspora (Gujarati Diaspora included) has settled.

4. Quality of Institution (NAAC Grade) and Faculty undertaking the Research The University was accredited with 4 stars by NAAC in the year 2000. The University was reaccredited with CGPA of 2.83 on 4 point scale at B Grade valid up to 16 September 2016.

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The university has initiated practice of providing seed money as a project grant especially to the new entrants in the faculty to promote research work. More than 25 research projects completed and more than 300 research papers published and PhD and MPhil research work done by faculty and students of humanities & social sciences during the last five years. Economics department has a CAS program. It has also made a contribution on Charutar region through a number of reports of small research projects and dissertations prepared on studies on Charutar region. English department completed DRS. Hindi and Gujarati got SAP DRS Project. Sociology had a centre for Diaspora for Area Study. The Centre for Diaspora studies, operational up to 31 March 2014 acquired a large number of documents in the form of reports, theses, dissertations etc on NRGs from Charutar region, their migration, contribution in the development on studies on Charutar region. Major research Area of Psychology Department is mentally disabled people.

5. Accountability of the Project The University and the Centre it establishes will sign an MoU with the SHEC, and SHEC will get this vetted by an Expert Committee under its overall supervision. SHEC will monitor the work done periodically as it deems fit. Since we are a state-aided University, we are accountable to the Government of Gujarat and the Government of India the various organs of which allot us funds for research and development. Therefore, the accountability question is settled. All we will need to do is to sign an MoU for these special funding.

6. Phases/Implementation Milestones and Plan of Action for 2015-16 and 2016-17

Plan of Work for 2015-16 During the 1St year, we will select the target research groups of students and teachers from the departments, colleges and other educational institutions and then organize the Area Research skill development programme. Experts will give them some structured guidelines and develop their self-determined research skills

- To point out research problem, the aim and objectives of research, formation of null hypothesis within structured guidelines and try to develop their research skill based on Area Studies.

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- To develop their skill of how to collect data, record required information and using an appropriate methodology for Area Studies.

- How to evaluate information/data using (a) prescribed criteria; (b) using self-determined criteria; and (c) using self-generated criteria based on experience, expertise and review of literature in Area Studies.

- How to work out an excellent structure and organization of ideas, focussed and innovative introduction of topic and research problem.

- How to make extent knowledge with new understanding and apply interdisciplinary approach of Area Studies.

Thus we shall encourage and give training to students and teachers doing research work in the field of Area Studies. We will identify subareas and groups of teachers who would collaborate in carrying out the research.

The focus will be on collecting primary & secondary materials and working out a research design during the 1st year. We shall seek to build a consensus on what would be relevant for further study, examine our research plans in the light of what we discover jointly.

Plan of Work for 2016-17 During the second year (2016-17), several seminars, workshops inter-area exchange programmes/interviews of experts/researchers/rural population of Charutar on community radio etc will be arranged. e- Archaives of Charutar region and museum will be established in this period. The feedback will be considered with an open mind and used in the draft papers in relevant sections. We will seek to generate consensus on the product of our research and get blind peer review by peer review teams.

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Each of the groups will work among themselves and with other groups together to finalise their reports and present them at three days national seminar .the final reports, proceedings of conference, books, research papers will be published by an editorial team constituted by our honourable Vice Chancellor. 7. Financial Resources, Financial Plan and Financial Sustainability Non-recurring No Particular Amount in Rs 1 Equipment 1. Computer with SOUL software and 5,00,000 assessment of centralizing data. (5) 2. Portable hand hold scanner 30,000 3. Reader printer 50,000 4. Desktop micro film camera 30,000 5. Audio-video system 70,000 6. Photocopier 80,000 7. Electronic copy power board for training 90,000 programme 8. Intel server Model no IBMX3500 3,00,000 9. H.P. laser jet printer 50,000 10. H.P. colour laser jet printer ,scanner 40,000 2 Renovation and up gradation 1,60,00,000 1. Library and Additional Space for Archives 1,15,00,000 2. Researcher Cabins 3. Coordinator Cabins 4. Meeting Room 3 Cabin furniture 30,00,000 Recurring No Particulars Amount in Rs 1 Contingency 6,00,000 2 Field work 5,00,000 3 Seminars, Workshops, Skill Development 10,00,000 Training Programmes 4 Hiring Service 5,00,000 5 Books, Journals 8,00,000 6 Publication of Books 2,50,000 7 Advisory Committee Meetings 2,50,000 8 Staff 44,30,000 1. Documentation officer 2. Two Project Assistants 3. Visiting Fellow Total 4,00,00,000

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8. Quality Improvement/Filling Gap Projection We shall identify subareas and groups of teachers who would collaborate in carrying out the research .a thorough review of literature available on various parts within the region will be undertaken by members of each group to identify research gaps in it. We shall organize two- three workshops on discussing ways and means to fill the gaps.

9. Evidence /Plan of Academic-Industry Partnership The university and industry interaction cell has been active to create database on need analysis of industries in the cell. Assist in signing of MOU, to offer training program relating to professionally oriented fields for small medium scale industries. So the centre will assist us with research on Area Studies.

10. Promotion of innovation The university looks ahead to create a dynamic atmosphere for research on the campus for the promotion of the innovation, university is providing seed grant to the new teachers. Simultaneously, workshop, research student’s seminar are being organized.

11. Manpower 1) Highly Qualified Professor (as Coordinator) 2) Documentation Officer 3) Two Project Assistants 4) Researcher Groups

The Core Committee and Peer Review Committee will be constituted by the honourable Vice Chancellor.

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Part-B

1. Existing Body of Research Work in the Area International status Major nations, emerged triumphant and powerful after World War-II, used a substantial part of their budgetary allocations to fund research on area studies in their universities and think-tank organisations. The purpose was to help develop a better perception of a potential nation or a geographical region for policy formulation based on an understanding the possibilities of emergence of newer nation states as future competitors or trade partners. The “Introduction” to research published in International Social Science Bulletin of the UNESCO in 1952, which reports how the American Political Science Association conducted a survey of ‘political science departments of 75 American universities’ in 1952. The results from the survey pointed out the fact that ‘308 of the 797 current research projects’ in them ‘dealt with international relations’, and ‘198 of these 308 were area studies. Thomas S. Simey (1952: 675) notes how “Contemporary area studies assume that the key to the understanding of a foreign area lies in the investigation of the specific phenomena which make up that area.” Universities in the Europe, Americas and Australia have traditionally engaged in work on Area Studies. In modern times, research on area studies of a country or region maps it in its entirety.

2. Rationale Sardar Patel University is a University established in rural settings in the heart of the Charutar belt in Central Gujarat, situated as it does, between two important rivers of Gujarat – Mahi and Vatrak – to contain migration from the rural to urban areas. It used to serve a geographical area of 8 sq kms in radius as clearly laid down in its Act, with Vallabh Vidyanagar at the centre. However, the Government of Gujarat has amended our Act and brought the institutions situated in Anand and within our area of function. It has 11 faculty disciplines, and 26 University Departments, besides 131 colleges affiliated to it as of today.

We are acutely aware of the fact that we will need to make our inquiry as systematic as possible, exploring the area using approaches that are interdisciplinary and even multi-disciplinary in their orientation because a uni-disciplinary approach will impose great restrictions. We wish to see the Centre for Area Studies of Charutar Region established in Sardar Patel University so as to attain

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our central objective of mapping whatever is feasible and possible and help create authentic and reliable documentation. This would add to the contribution this University has made to Diaspora Studies.

UGC had sanctioned a project-based Research Centre for Diaspora Studies earlier under which we were able to undertake research projects on Non-Resident Gujaratis (NRGs) from Charutar region, organized International Seminars and Conferences around this theme, and published collections of scholarly papers in the form of books in print. Our Centre for Diaspora Studies, operational up to 31 March 2014 acquired a large number of documents in the form of Government and Non-Government Reports, PhD theses, MPhil Dissertations etc on NRGs from Charutar region, their migration, contribution in the development of the region.

The Department of Economics in the university also has made a contribution on Charutar region through a number of reports of small research projects, and MPhil Dissertations prepared on studies on Charutar region.

3. Credibility of Persons Involved The Area Studies will be conducted by a highly qualified coordinator who will be a senior faculty member of a given department with a specialization in the concerned Area. Research staff across the various departments of university selected by honourable VC of university for all the staff involved, who have Charutar as their special area research.

4. Significance and Expected Contribution of Project Charutar of yesteryears, known for its enterprising tobacco-growing farming, and business communities, has provided the fulcrum around which the region of central Gujarat has rotated, in many ways, all through the history of independent India in the last 74 years. It has seen unprecedented growth and development both in the context of Gujarat and of the country as a whole. Shri Sardar Patel dreamt of Charutar occupying a central position as the ‘centre’ of Gujarat and India.

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Etymologically, chāru means beautiful and Charutar would mean a beautiful land. This geographical region of enterprising farmers and entrepreneurs is located between two major rivers in Gujarat – Mahi and Vatrak – flanked by Mahemadabad Taluka of Kheda District in the North; Matar in Kheda District in the North-west, Khambhat Taluka in the West, Bhadran Taluka of in the South; and Thasra Taluka in Kheda District in the East; and Karamsad, Sojitra, Petlad, Dharmaj, Vaso, and Pij in the Centre.

(Source: Charutar Chaud-Gam Patidar Samaj Website)

It was the Sardar’s dream and his advice to Shri Baikaka that motivated the latter to work for the upliftment of villages and work toward arresting migration of population from rural to urban areas for access to better educational, employment and health facilities.

Shri Bhaikaka, one of the founding fathers of Vallabh Vidyanagar and Sardar Patel University, made common cause with a renowned teacher of the times, Shri Bhikabhai, to establish a township called Vallabh Vidyanagar1 at the centre of a tri-junction of the villages Karamsad and Bakrol and the township of Anand where Shri Tribhuvandas Patel made common cause with Dr Varghese Kurien to found federation of Milk Cooperatives and establish Amul Dairy.

1 Vallabh Vidyanagar and Sardar Patel University are named after the revered ‘Sardar’ Vallabhbhai Patel; ‘Vallabh’. Vallabh tagged with Vidyanagar (educational township) and Sardar Patel in Sardar Patel University are both taken from his full name ‘Sardar’ Vallabhbhai (Jhaverbhai) Patel. ‘Sardar’ is a Hindi word for ‘Leader’. Sardar Patel was a staunch follower of Gandhiji’s philosophy of Non-Violence. Gandhi fondly called him ‘Sardar’ 1928 onward after Shri Sardar Patel led the Bardoli Satyagraha Movement successfully, even as Gandhiji had called off the Peaceful Civil Disobedience Movement temporarily after violence erupted during the Chauri Chaura Movement where may. Gandhiji did not wish to allow the movement against the British to slide into violence and anarchy.

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Opportunities for education were created through a string of colleges established by Shri Bhaikaka through Charutar Vidya Mandal, beginning 1946 followed by Sardar Patel University in 1955 in the newly-founded Vallabh Vidyanagar; those for employment through Pole factory and Charutar Grammoddhar Sahakari Mandal and for employment generation, we have a twin township called Vitthal Udyognagar which has a big unit of Gujarat Industrial Corporation aimed at facilitating the establishment of industries now; and for health through Charutar Arogya Mandal in Arogyanagar, between Karamsad and Valasan villages, which houses Sri Krishna Medical (Multispeciality) Hospital and Sri Pramukhswami Medical College, founded by Shri H M Patel, Shri Bhaikaka’s follower and chosen successor, a renowned visionary (former civil servant looking after finance as secretary, GoI (pre-and post-partition); ex-Union Minister for Finance and Home, GoI; and an far-sighted educationist.

The dream close to Shri Sardar Patel’s heart began to be realized gradually as the strategy of the visionaries not only helped arrest migration from rural to urban areas but also ended up attracting students from different parts of Gujarat, India and other countries to which families from Gujarati had migrated in the past. A veritable mix of all this has helped create a vibrant economy in Charutar region. New educational townships seeking to replicate the Vallabh Vidyanagar- Sardar Patel University model.

5. Clarity of Aims, Objectives and Research Questions Aim and Objectives - To bring knowledge of regions to the core of intellectual disciplines. - To conduct research to promote inter area comparative perspectives. - To promote holistic understanding of the area with its cultural, social, economic and strategic specificities. - To contribute towards Indian perspectives of area and issues. - To promote alternative paradigm of area studies from the perspective of post independence. - To collect, collate, categorise, report and publish the research output in different volumes and to put all these volumes in the public domain both in

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the form of books in print and electronic forms at a price fixed by university and made available by the centre. - To focus on emerging realities of area and to find out problems’ solution.

6. Methodology We will make use a variety of a mixed methodology depending upon the subareas, for example, literary works would be mapped through library, desk, qualitative research, wherein interview schedules and case studies would also have a role to play. Departments under the social sciences would use empirical methodology to undertake qualitative and quantitative research. Fieldwork would be used where necessary in collecting quantitative data.

7. Definition and Significance/Value Of Research Outputs The Area Studies project will coordinate many events annually which interact ally nourish and culturally enrich Charutar region and all who attend.

The activities of Area Studies will be supported by dedicated joint appointed and associate faculty across the university.

The project will balance a liberal arts and professional approach to understanding the economic potential, rich cultural resources and basic need for to inter culture relationship with others. It will undertake outreach activities to promote understanding and dissemination of information on the area by organizing workshops, lectures, interactive programme in public domain. Collaboration with relevant bodies and institutions, cultural bonding will be an integral component of the project.

8. Inter-Disciplinary/Multi-Disciplinary Orientation and Multi-Institution

Networking An area study project will function in a multi-disciplinary manner and have a wider canvas through a proper organization structure in the university structure so that it will effectively utilize and expertise, facilities of the departments available in the university. The departments of

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English, Hindi, Guajarati, Sanskrit (Humanities), the departments of History, Sociology, Social Work, Psychology, Political Science etc will pool their human and library resources to collaborate among themselves.

9. Anticipated Outcome of the Proposal Cultural bonding: This will be is an integral component of the programme.

Area Studies is a scientific study of area. So the study will be useful to solve the problems of society. The new intensity of interface among the nations and between the areas triggered by time-space compression. It will be reflected in the research work of PhD degree.

10. Research and Innovation Culture Creation among Affiliated Colleges Collaboration with affiliated colleges will be an integral Component of the project. Sardar Patel University has 26 university departments besides 131 colleges affiliated to it. The Annual Reports of the University submitted regularly to the Government of Gujarat and the research funding various governmental and research organizations make to us stands testimony to our research. This is not limited to the University but is true of most of the good colleges affiliated to the University.

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Annexure-13 Detail Presentations by Proposed Universities

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