DOCSLIB.ORG

RISHABH's Ipad

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
RISHABH's Ipad IMA WHITE PAPER ON NON PRESCRIPTION DRUGS The import, manufacture, distribution and sale of drugs and cosmetics in India is regulated by the Drugs and Cosmetics Act, 1940 (hereinafter referred to as ―DCA‖) and Drugs and Cosmetics Rules, 1945 (hereinafter referred to as ―DCR‖). The profession and practice of pharmacy and constitution of pharmacy council is being regulated by The Pharmacy Act, 1948. DEFINITION OF DRUG The term ―drug‖ has been defined in Section 3(b) of the DCA which is an inclusive definition. According to Section 3(b) of DCA ―drug‖ includes— (i) all medicines for internal or external use of human beings or animals and all substances intended to be used for or in the diagnosis, treatment, mitigation or prevention of any disease or disorder in human beings or animals, including preparations applied on human body for the purpose of repelling insects like mosquitoes; (ii) such substances (other than food) intended to affect the structure or any function of the human body or intended to be used for the destruction of vermin or insects which cause disease in human beings or animals, as may be specified from time to time by the Central Government by notification in the Official Gazette; (iii) all substances intended for use as components of a drug including empty gelatin capsules; and (iv) such devices intended for internal or external use in the diagnosis, treatment, mitigation or prevention of disease or disorder in human beings or animals, as may be specified from time to time by the Central Government by notification in the Official Gazette, after consultation with the Board; According to Section 2 of the Pharmacy Act, the term drug means any substance or mixture of substances manufactured, sold or represented for use in- (a) The diagnosis, treatment; mitigation or prevention of a-disease, disorder, abnormal physical state or the symptoms thereof in man or animal; (b) Restoring, correcting or modifying organic functions in man or.anima1; (c) disinfection in premises in which food is manufactured, prepared, preserved, packaged or stored for sale or sold or for the control of vermin or insects in such premises; According to Section 2(b) of The Drugs And Magic Remedies (Objectionable Advertisements) Act, 1954, the term drug‘ includes: (i) A medicine for the internal or external use of human beings or animals (ii) Any substance intended to be used for or in the diagnosis, cure, mitigation, treatment or prevention of disease in human beings or animals (iii) Any article, other than food, intended to affect or influence in any way the structure or any organic function of the body of human beings or animals; (iv) Any article intended for use as a component of any medicine, substance or article, referred to in sub-clauses (i), (ii) and (iii). According to Section 2(f) of Drugs (Prices Control) Order, 1995, the definition of term drugs includes: (i) all medicines for internal or external use of human beings or animals and all substances intended to be used for, or in the diagnosis treatment, mitigation, or prevention of any disease or disorder in human beings or animals, including preparations applied on human body for the purpose of repelling insects like mosquitoes (ii) such substances, intended to affect the structure or any function of the human or animal body or intended to be used for the destruction of vermin or insects which cause disease in human beings or animals, as may be specified from time to time by the Government by notification in the Official Gazette (iii) bulk drugs and formulations The definition of the term drug as mentioned above in various acts neither classify / divide the drugs into allopathic drugs, ayurvedic, siddha or unani drug or homeopathic drug nor does it discriminate between prescribed drugs or non prescribed drugs. Further, the definition of drug does not define the term over the counter drugs (OTC) as commonly known in USA which can be sold or purchased by any person over the counter. CLASSIFICATION OF DRUG EXCLUDING HOMEOPATHIC DRUGS Allopathic Drugs / Medicines The provisions of Drugs & Cosmetics Act, does not define the term allopathic drug or modern medicine. Indian Medical Council Act, 1956 (hereinafter referred to as IMC Act) is an act to provide for the reconstitution of the Medical Council of India and the maintenance of a Medical Register for India and for matters connected therewith. According to Section 2 (g) of Indian Medical Council Act, 1956, "medicine" means modern scientific medicine in all its branches and includes surgery and obstetrics, but does not include veterinary medicine and surgery. Indian Medical Degrees Act, 1916 was enacted to regulate the grant of titles implying qualifications in Western medical science and the assumption and use by unqualified persons of such titles. According to Section 2 of the Indian Medical Degrees Act, 1916, ―Western Medical Science‖ means the Western methods of Allopathic medicine, Obstetrics and Surgery, but does not include the Homeoptahic or Ayurvedic or Unani System of medicine. Thus, Indian Medical Degrees Act does not grant degrees of Ayurvedic, Unani system of medicines. Ayurvedic, Siddha And Unani Drug According to Section 3(a) of Drugs and Cosmetics Act, 1940, Ayurvedic, Siddha or Unani drug‖ includes all medicines intended for internal or external use for or in the diagnosis, treatment, mitigation or prevention of disease or disorder in human beings or animals, and manufactured exclusively in accordance with the formulae described in, the authoritative books of Ayurvedic, Siddha and Unani Tibb systems of medicine, specified in the First Schedule. The Indian Medicine Central Council Act, 1970 (hereinafter referred to as ―IMCC Act) has been framed to provide for the constitution of a Central Council of Indian Medicine and the maintenance of a Central Register of Indian Medicine and for matters connected therewith. According to Section 2(e) of the Indian Medicine Central Council Act, "Indian Medicine" means the system of Indian medicine commonly known as Ashtang Ayurveda, Siddha or Unani Tibb whether supplemented or not by such modern advances as the Central Council may declare by notification from time to time. DEFINITION OF FOOD The Food Safety and Standards Act, 2006 has been framed to consolidate the laws relating to food and to establish the Food Safety and Standards Authority of India for laying down science based standards for articles of food and to regulate their manufacture, storage, distribution, sale and import, to ensure availability of safe and wholesome food for human consumption and for matters connected therewith or incidental thereto. According to Section 3(j) of Food Safety and standards Act, 2006, ―Food‖ means any substance, whether processed, partially processed or unprocessed, which is intended for human consumption and includes primary food to the extent defined in clause (zk), genetically modified or engineered food or food containing such ingredients, infant food, packaged drinking water, alcoholic drink, chewing gum, and any substance, including water used into the food during its manufacture, preparation or treatment but does not include any animal feed, live animals unless they are prepared or processed for placing on the market for human consumption, plants, prior to harvesting, drugs and medicinal products, cosmetics, narcotic or psychotropic substances : Provided that the Central Government may declare, by notification in the Official Gazette, any other article as food for the purposes of this Act having regards to its use, nature, substance or quality POISONOUS SUBSTANCES According to Section 4 of DCA, any substance specified as poisonous by rule made under Chapter III or Chapter IV or Chapter IVA shall be deemed to be a poisonous substance for the purposes of Chapter III or Chapter IV or Chapter IVA, as the case may be. SCHEDULE DRUGS and NON SCHEDULE DRUGS According to the provisions of Drugs & Cosmetics Act, 1940 and Drugs & Cosmetics Rules, 1945 certain restriction has been imposed on the manufacture, sale, advertisement, labeling, packing, etc. of certain drugs. Thus, the allopathic drugs and ayurvedic, siddha and unani drgs can further be classified as i) Schedule Drugs / Prescription Drugs: The List of schedule / prescription drugs of allopathic and ayurvedic, siddha and unani drugs is mentioned in Schedules appended to the Drugs and Cosmetics Rules, 1945. The drugs mentioned in Schedule E1, G, H, H1 and X appended to the Drugs and Cosmetics Rules, 1945 can be termed as Schedule Drugs / Prescription drugs. ii) Non Schedule / Non Prescription Drugs: There are certain drugs as mentioned in Schedule K of Drugs & Cosmetics Rules, 1945 which are exempted from the various restrictions as imposed in case of schedule drugs. iii) Non Schedule / Non Prescription Drugs not mentioned in Schedule K: There are certain drugs other than those as mentioned in Schedule K which are exempted from various restrictions as imposed in case of schedule drugs / prescription drugs. These are those drugs which are not mentioned in any of the Schedule appended to the Drugs and Cosmetics Rules, 1945. However, there is no exhaustive list of non schedule drugs. SCHEDULE / PRESCRIPTION DRUGS The drugs mentioned in Schedule E1, G, H, H1 and X appended to the Drugs and Cosmetics Rules, 1945 can be termed as Schedule Drugs / Prescription drugs. The drugs mentioned in Schedule E1, G, H, H1 and X along with various restrictions as imposed on these drugs are discussed hereinunder: SCHEDULE E(I) - List of poisonous substances under the ayurvedic (including Siddha) and Unani Systems of Medicine Restriction on Labeling According to Rule 161(2) of Drugs and Cosmetics Rules, 1945, the container of medicines for internal use made up ready for the treatment of human ailments shall, if it is made up from a substance specified in Schedule E(1) be labeled conspicuously with the words: Caution: To be taken under medical supervision‘ both in English and Hindi language.
Load more

Recommended publications
  • A Review on the Current Classification and Regulatory Provisions for Medicines in Drug & Cosmetic Act, in the Light of Present Day Context
    Section Pharmaindustry Commentary A Review on the Current Classification and Regulatory Provisions for Medicines in Drug & Cosmetic Act, in the light of Present Day Context Prashant Tandon1, Varun Gupta2, Ashish Ranjan3, Purav Gandhi4, Anand Kotiyal5, 3 Aastha Kapoor 3 1Founder ;2VP & Head Medical Affair; Manager Medical Affair; 5Drug Data Analyst Medical Affair, 1mg Technologies Private Limited, 4th Floor, Motorola Building, MG Road, Sector 14, Gurugram, Haryana, 122001. 4Founder, Remedy Social, C/602, Tulip Citadel, Shreyas Tekra, Ambawadi, Ahmedabad 380015, Gujarat. ABSTRACT______________________________________________________________ Background: Current classification of medicines in Conclusions: We have recommended a revised drug India under Drug and Cosmetic Act into Schedule G, classification system that is more comprehensive in coverage and H, H1, X is outdated, evolved through patchwork over eliminates the overlaps between classes. Moreover, considering the years and needs to be thoroughly updated. The the implementation challenges for such a drug classification primary aim of the scheduling system is to ensure system in the diverse and fragmented ecosystem in India, we appropriate access to medicines while balancing recommend a technology backed platform to help monitor the public health and safety. India is experiencing a rapid implementation. transition with the rising burden of chronic non- communicable diseases where regular access of Key words: Drug Classification System, Drug and Cosmetic Act affordable medicines is critical for chronic disease India, Digitization of Prescriptions, Drug Schedules in India, management to prevent complications. Methods: We Schedule H, Monitoring Drug Schedule System analyzed drugs commonly selling across India, Received: 01.09.17 | Accepted:16.09.17 through multiple information sources including 1mg drug database, PharmaTrac (AIOCD-AWACS), Corresponding Author inventory data from distributors and retailers, Dr.
    [Show full text]
  • Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017
    Q UO N T FA R U T A F E BERMUDA PHARMACY AND POISONS (THIRD AND FOURTH SCHEDULE AMENDMENT) ORDER 2017 BR 111 / 2017 The Minister responsible for health, in exercise of the power conferred by section 48A(1) of the Pharmacy and Poisons Act 1979, makes the following Order: Citation 1 This Order may be cited as the Pharmacy and Poisons (Third and Fourth Schedule Amendment) Order 2017. Repeals and replaces the Third and Fourth Schedule of the Pharmacy and Poisons Act 1979 2 The Third and Fourth Schedules to the Pharmacy and Poisons Act 1979 are repealed and replaced with— “THIRD SCHEDULE (Sections 25(6); 27(1))) DRUGS OBTAINABLE ONLY ON PRESCRIPTION EXCEPT WHERE SPECIFIED IN THE FOURTH SCHEDULE (PART I AND PART II) Note: The following annotations used in this Schedule have the following meanings: md (maximum dose) i.e. the maximum quantity of the substance contained in the amount of a medicinal product which is recommended to be taken or administered at any one time. 1 PHARMACY AND POISONS (THIRD AND FOURTH SCHEDULE AMENDMENT) ORDER 2017 mdd (maximum daily dose) i.e. the maximum quantity of the substance that is contained in the amount of a medicinal product which is recommended to be taken or administered in any period of 24 hours. mg milligram ms (maximum strength) i.e. either or, if so specified, both of the following: (a) the maximum quantity of the substance by weight or volume that is contained in the dosage unit of a medicinal product; or (b) the maximum percentage of the substance contained in a medicinal product calculated in terms of w/w, w/v, v/w, or v/v, as appropriate.
    [Show full text]
  • Pharmacy and Poisons Act 1979
    Q UO N T FA R U T A F E BERMUDA PHARMACY AND POISONS ACT 1979 1979 : 26 TABLE OF CONTENTS PART I PRELIMINARY 1 Short title 2 Interpretation PART II THE PHARMACY COUNCIL 3 The Pharmacy Council 4 Membership of the Council 4A Functions of the Council 4B Protection from personal liability 4C Annual Report 5 Proceedings of the Council, etc PART III REGISTRATION OF PHARMACISTS 6 Offence to practise pharmacy if not registered 7 Registration as a pharmacist 7A Re-registration as non-practising member 7AA Period of validity of registration 8 Code of Conduct 9 Pharmacy Profession Complaints Committee 10 Investigation of complaint by Committee 10A Inquiry into complaint by Council 10B Inquiry by Council of its own initiative 11 Surrender of registration 12 Restoration of name to register 1 PHARMACY AND POISONS ACT 1979 13 Proof of registration 14 Appeals 14A Fees 14B Amendment of Seventh Schedule 15 Regulations for this part PART IV REGISTRATION OF PHARMACIES 16 Register of pharmacies 17 Registration of premises as registered pharmacies 18 Unfit premises: new applications 19 Unfit premises: registered pharmacies 20 Appeals 21 When certificates of unfitness take effect 22 Regulations for this Part PART V CONTROL OF PRESCRIPTIONS AND IMPORTATION 23 Prescriptions to be in a certain form 23A Validity of a prescription 24 Supply by registered pharmacist of equivalent medicines 25 Restrictions on the importation of medicines 26 Declaration relating to imported medicines [repealed] PART VI CONTROL OF DRUGS 27 Certain substances to be sold on prescription
    [Show full text]
  • University of Groningen Multi-Residue Analysis of Growth Promotors In
    University of Groningen Multi-residue analysis of growth promotors in food-producing animals Koole, Anneke IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 1998 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): Koole, A. (1998). Multi-residue analysis of growth promotors in food-producing animals. s.n. Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date: 25-09-2021 APPENDIX 1 OVERVIEW OF RELEVANT SUBSTANCES This appendix consists of two parts. First, substances that are relevant for the research presented in this thesis are given. For each substance CAS number (CAS), molecular weight (MW), bruto formula (formula) and if available UV maxima and alternative names are given. In addition, pKa values for the ß-agonists are listed, if they were available.
    [Show full text]
  • 有限公司 Testosterones
    ® 伊域化學藥業（香港）有限公司 YICK-VIC CHEMICALS & PHARMACEUTICALS (HK) LTD Rm 1006, 10/F, Hewlett Centre, Tel: (852) 25412772 (4 lines) No. 52-54, Hoi Yuen Road, Fax: (852) 25423444 / 25420530 / 21912858 Kwun Tong, E-mail: [email protected] YICK -VIC 伊域 Kowloon, Hong Kong. Site: http://www.yickvic.com Testosterones Product Code CAS Product Name MIS-42658 1043-10-3 (8S,9S,10R,11S,13S,14S,17S)-11,17-DIHYDROXY-10,13,17-TRIMETHYL-2,6,7,8,9,11,12,14,15,16-DECAHYDRO-1H-CYCLOPENTA[A]PHENA NTHREN-3-ONE UNIE-13864 564-35-2 11-KETOTESTOSTERONE PH-1081U 17-ALPHA-HYDROXYTESTOSTERONE ACETATE MIS-39218 51154-09-7 17ALPHA-METHYLTESTOSTERONE 4,5-EPOXIDE PH-1121 72-63-9 17BETA-HYDROXY-17-METHYLANDROSTA-1,4-DIEN-3-ONE MIS-34565 5585-85-3 17BETA-HYDROXY-17-METHYLANDROSTA-4,6-DIEN-3-ONE PH-1081S 17BETA-HYDROXYANDROST-1-ENE-3-ONE TETRAHYDROPYRANYL ETHER PH-1081VA 1-TESTOSTERONE ETHYL CARBONATE PH-1081VB 1-TESTOSTERONE METHYL CARBONATE PH-1081VC 1-TESTOSTERONE PROPYL CARBONATE PH-1081HB 1-TESTOSTERONE UNDECANOATE UNIE-15172 2141-17-5 4-HYDROXYTESTOSTERONE UNIE-13597 62-99-7 6BETA-HYDROXYTESTOSTERONE SPI-4361 14531-84-1 6-DEHYDRO-19-NORTESTOSTERONE PH-1081PK 1057-07-4 ANDROSTANOLONE 17-BENZOATE Copyright © 2018 YICK-VIC CHEMICALS & PHARMACEUTICALS (HK) LTD. All rights reserved. Page 1 of 3 Product Code CAS Product Name PH-1133 1605-89-6 BOLASTERONE UNIE-8525 CHLORDEHYDROMETHYLTESTOSTERONE PH-1081JA 1093-58-9 CLOSTEBOL PH-1081JB 855-19-6 CLOSTEBOL ACETATE SPI-0027GA 481-30-1 EPITESTOSTERONE SPI-0027GB EPITESTOSTERONE ACETATE PH-1081K 434-03-7 ETHISTERONE PH-1136B 76-43-7
    [Show full text]
  • Mucoadhesive Drug Delivery Devices and Methods Of
    (19) TZZ___T (11) EP 1 691 746 B1 (12) EUROPEAN PATENT SPECIFICATION (45) Date of publication and mention (51) Int Cl.: of the grant of the patent: A61F 13/00 (2006.01) A61K 9/00 (2006.01) 27.05.2015 Bulletin 2015/22 A61K 9/16 (2006.01) A61K 38/38 (2006.01) A61K 47/10 (2006.01) (21) Application number: 04813308.6 (86) International application number: (22) Date of filing: 08.12.2004 PCT/US2004/040975 (87) International publication number: WO 2005/055945 (23.06.2005 Gazette 2005/25) (54) MUCOADHESIVE DRUG DELIVERY DEVICES AND METHODS OF MAKING AND USING THEREOF MUKOADHÄSIVE ARZNEIMITTELABGABEVORRICHTUNGEN UND VERFAHREN ZU IHRER HERSTELLUNG UND VERWENDUNG DISPOSITIFS D’ADMINISTRATION DE MEDICAMENTS MUCOADHESIFS ET PROCEDES DE FABRICATION ET D’UTILISATION ASSOCIES (84) Designated Contracting States: • BERG, Eric, P. AT BE BG CH CY CZ DE DK EE ES FI FR GB GR Plymouth, MN 55447 (US) HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (74) Representative: Robertson, James Alexander et al (30) Priority: 08.12.2003 US 527962 P Marks & Clerk LLP 90 Long Acre (43) Date of publication of application: London WC2E 9RA (GB) 23.08.2006 Bulletin 2006/34 (56) References cited: (73) Proprietor: Gel-Del Technologies, Inc. WO-A1-01/28524 WO-A1-99/32107 St. Paul, MN 55114 (US) WO-A1-02/058735 US-A- 5 385 606 US-A- 5 863 554 US-A1- 2002 141 945 (72) Inventors: US-A1- 2003 215 515 • MASTERS, David, B. Hastings, MN 55033 (US) Note: Within nine months of the publication of the mention of the grant of the European patent in the European Patent Bulletin, any person may give notice to the European Patent Office of opposition to that patent, in accordance with the Implementing Regulations.
    [Show full text]
  • Poisons List (Jersey) Order 1986
    POISONS LIST (JERSEY) ORDER 1986 Revised Edition 20.775.60 Showing the law as at 31 August 2004 This is a revised edition of the law Poisons List (Jersey) Order 1986 Arrangement POISONS LIST (JERSEY) ORDER 1986 Arrangement Article 1 Poisons List ..................................................................................................... 5 2 Citation ............................................................................................................ 5 SCHEDULE 6 THE POISONS LIST 6 PART 1 6 PART 2 50 PART 3 52 Supporting Documents ENDNOTES 53 Table of Legislation History......................................................................................... 53 Table of Renumbered Provisions ................................................................................. 53 Table of Endnote References ....................................................................................... 53 Revised Edition – 31 August 2004 Page - 3 20.775.60 Poisons List (Jersey) Order 1986 Article 1 POISONS LIST (JERSEY) ORDER 1986 THE HEALTH AND SOCIAL SERVICES COMMITTEE in pursuance of Article 8 of the Pharmacy and Poisons (Jersey) Law 1952,1 orders as follows – Commencement [see endnotes] 1 Poisons List The list of substances which are to be treated as poisons for the purposes of the Pharmacy and Poisons (Jersey) Law 1952,2 shall be as set out in the Schedule to this Order. 2 Citation This Order may be cited as the Poisons List (Jersey) Order 1986. Revised Edition – 31 August 2004 Page - 5 20.775.60 SCHEDULE Poisons List (Jersey) Order
    [Show full text]
  • Alltech® Drug Standards for the Forensic, Clinical & Pharmaceutical Industries OH
    Alltech® Drug Standards For the Forensic, Clinical & Pharmaceutical Industries OH H3C H H H3C H HO Catalog #505B Our Company Welcome to the Grace's Alltech® Drug Standards Catalog W. R. Grace has manufactured high-quality silica for over 150 years. Grace has been behind the scenes for the past 30 years supplying silica to the chromatography industry. Now we’re in the forefront moving beyond silica, developing and delivering innovative complementary products direct to the customer. Grace Davison Discovery Sciences was founded on Grace’s core strength as a premier manufacturer of differentiated media for SPE, Flash, HPLC, and Process chromatography. This core competency is further enhanced by bringing seven well-known global separations companies together, creating a powerful new single source for all your chromatography needs. A Full Portfolio of Chromatography Products to Support Drug Standards: • HPLC Columns • HPLC Accessories • Flash Products • TLC Products • GC Columns • GC Accessories • SPE and Filtration • Equipment • Syringes • Tubing • Vials For complete details, download the Chromatography Essentials catalog from the Grace web site or contact your customer service representative. Alltech - Part of the Grace Family of Products In 2004, Alltech Associates Inc. was acquired by Grace along with the Alltech® Drug Standards product line. Through investment in research and strategic acquisitions, Grace has expanded our product range and global reach while drawing upon the support of the Grace corporate infrastructure and more than 6000 employees globally to support scientific research and analysis worldwide. With key manufacturing sites in North and South America, Europe, and Asia, plus an extensive international sales and distribution network, separation scientists throughout the world can count on timely delivery and expert local technical service.
    [Show full text]
  • Georgia State Forensic Drugs
    Comprehensive Forensic FT-IR Collection Library Listing – 4,286 spectra This extensive library contains materials not only of forensic interest but also for general problem solving and identification of unknown substances in industry and academia. The wide range of items include drugs, clandestine lab chemicals, explosives, paints, fabrics, dyes, polymers, inorganic compounds, pigments, adhesives, and other common materials. The library consists of 4,286 spectra that were acquired from a wide range of laboratories involved in forensic investigations. The collection includes the following classes of compounds: • Drugs of abuse, scheduled materials • Pharmaceuticals, vitamins and excipients • Clandestine lab materials and intermediates • Solvents, organic chemicals and hazardous chemicals • Accelerants • Lubricants and natural oils • Explosives, pyrotechnics, primers, powders and boosters • Herbal and plant material and fibers • Automobile paint vehicles, pigments, primers and clear coats • Textiles, natural and man-made fibers, carpet materials • Paints, coatings, varnishes, oils • Dyes and stains • Polymers, monomers, copolymers, plasticizers and rubbers • Inorganics, pigments, minerals and clays • Tape, adhesives, sealants, glues, caulks and putties • Crystal test derivatives and intermediates • Household chemicals, cleaning agents, surfactants and pesticide All spectra were measured using micro or macro Diamond ATR, thin films on salt windows or KBr pellets at 4 cm-1 spectral resolution. Comprehensive Forensic FT-IR Collection Index
    [Show full text]
  • A Review of the Presence of Doping Substances in Dietary Supplements Used in Sports
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Repositorio Institucional de la Universidad de Alicante Review Intended or Unintended Doping? A Review of the Presence of Doping Substances in Dietary Supplements Used in Sports José Miguel Martínez-Sanz 1,2,*, Isabel Sospedra 1,2, Christian Mañas Ortiz 3, Eduard Baladía 2,4, Angel Gil-Izquierdo 2,5 and Rocio Ortiz-Moncada 2,6 1 Nursing Department, Faculty of Health Sciences, University of Alicante, 03690 Alicante, Spain; [email protected] 2 Research Group on Food and Nutrition (ALINUT), University of Alicante, 03690 Alicante, Spain; [email protected] (E.B.); [email protected] (A.G.-I.); [email protected] (R.O.-M.) 3 Pharmacy faculty, University of Valencia, 46100 Valencia, Spain; [email protected] 4 Evidence-Based Nutrition Network (RED-NuBE), Spanish Academy of Nutrition and Dietetics (AEND), 31006 Navarra, Spain 5 Quality, Safety, and Bioactivity of Plant Foods Group, Department of Food Science and Technology, CEBAS-CSIC, University of Murcia, 30100 Murcia, Spain 6 Department of Community Nursing, Preventive Medicine and Public Health and History of Science Health, University of Alicante, 03690 Alicante, Spain * Correspondence: [email protected] Received: 29 August 2017; Accepted: 29 September 2017; Published: 4 October 2017 Abstract: Introduction: The use of dietary supplements is increasing among athletes, year after year. Related to the high rates of use, unintentional doping occurs. Unintentional doping refers to positive anti-doping tests due to the use of any supplement containing unlisted substances banned by anti- doping regulations and organizations, such as the World Anti-Doping Agency (WADA).
    [Show full text]
  • 1. All of the Following Ate Psychotropic Substances, Except: 1
    1. All of the following ate psychotropic substances, except: 1. Amobarbital 2. Meprobamate 3. Barbital 4. All of the above 2. As per schedule P of Drugs and Cosmetics Act, the Diphtheria toxoid has expiry period of : 1. 6 months 2. 12 months 3. 2 years 4. 5 years 3. Chloramphenicol comes under schedule : 1. G 2. H 3. W 4. P 4. Example of Narcotic drug is : 1. Coca 2. Opium 3. Charas 4. Doxapram 5. Ergot and its preparation belongs to schedule : 1. P 2. Q 3. C1 4. L 6. Schedule X drug is : 1. Amphetamine 2. Cyclobarbital 3. Glutethimide 4. All of the above 7. Drug Inspector is appointed under section : 1. 19 2. 42 3. 21 4. 30 8. Schedule M and Y were introduced in Drugs and Cosmetics Act in : 1. 1976 2. 1982 3. 1988 4. 1980 9. Example of Schedule G drug is : 1. Tetracycline 2. Ampicillin 3. Ibuprofen 4. Tolbutamide 10. Example of Schedule X drug is : 1. Diazepam 2. Emetine 3. Quinidine 4. Ciprofloxacin 11. Opium has been under legislative control since : 1. 1820 2. 1857 3. 1925 4. 1949 12. Standards for mechanical contraceptives are given in schedule : 1. S 2 R 3. Q 4. T 13. The Drugs and Cosmetics Act has been divided into ...... parts 1. 15 2. 16 3. 18 4. 24 14. The Central Drugs Laboratory is established in : 1. Calcutta 2. Lucknow 3. Mumbai 4. Kasauli 15. The members of the D.T.A.B. hold the office for : 1. 1 year 2. 3 years 3.
    [Show full text]
  • Transformations of Steroid Esters by Fusarium Culmorum Alina S´ Wizdor*, Teresa Kołek, and Anna Szpineter
    Transformations of Steroid Esters by Fusarium culmorum Alina S´ wizdor*, Teresa Kołek, and Anna Szpineter Department of Chemistry, Agricultural University, Norwida 25, 50-375 Wrocław, Poland. Fax: 0048-071-3283576. E-mail: [email protected] * Author for correspondence and reprint requests Z. Naturforsch. 61c, 809Ð814 (2006); received April 6/May 15, 2006 The course of transformations of the pharmacological steroids: testosterone propionate, 4-chlorotestosterone acetate, 17-estradiol diacetate and their parent alcohols in Fusarium culmorum AM282 culture was compared. The results show that this microorganism is capable of regioselective hydrolysis of ester bonds. Only 4-ene-3-oxo steroid esters were hydrolyzed at C-17. 17-Estradiol diacetate underwent regioselective hydrolysis at C-3 and as a result, estrone Ð the main metabolite of estradiol Ð was absent in the reaction mixture. The alcohols resulting from the hydrolysis underwent oxidation at C-17 and hydroxylation. The same products (6- and 15α-hydroxy derivatives) as from testosterone were formed by transformation of testosterone propionate, but the quantitative composition of the mixtures obtained after transformations of both substrates showed differences. The 15α-hydroxy deriv- atives were obtained from the ester in considerably higher yield than from the parent alcohol. The presence of the chlorine atom at C-4 markedly reduced 17-saponification in 4-chloro- testosterone acetate. Only 3,15α-dihydroxy-4α-chloro-5α-androstan-17-one (the main prod- uct of transformation of 4-chlorotestosterone) was identified in the reaction mixture. 6- Hydroxy-4-chloroandrostenedione, which was formed from 4-chlorotestosterone, was not de- tected in the extract obtained after conversion of its ester.
    [Show full text]