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Technetium 99m Generators from And all ClntiChem Technetium 99m Cintichem, Inc. have 3.77 inches of lead Generators from Medi-Physics surrounding the column for maximum incorporate the following important protection. The secondary advantages: shield adds 5/8" more lead to make our •A NEW STERILE NEEDLE is utilized for generators safer yet. And only MPI Gen each elution, reducing the chances of a erators offer depleted shielding septic or pyrogenic situation occurring in higher calibrations, designed to max in routine clinical usage. imize radiation protection, convenience •See, 10cc AND 20cc EVACUATED and reduce costs. With 20 sizes and 2 ELUTION VIALS are available, allowing calibration days, we can meet virtually you to optimize the elution concentra every need. tion to meet your needs. Convenience is also designed INTO every •RIGID QUALITY CONTROL TESTING, MPI Generator. It is the only generator which includes an elution check on with rapid, easy horizontal elution via a each Generator, assures that it meets shielded elution port. The simple, one- our rigid internal specifications. The step elution reduces work time while assurance that 20 years experience in eliminating direct eye exposure during nuclear brings. the elution process. Eluate sterility is •ACCESSIBLE CUSTOMER SERVICE assured by the 0.22 micron filter on the on toll free telephone numbers. Our terminal fluid line and an autoclaved service personnel have in depth back column. grounds in research, development, technical and clinical applications in . We are concerned about your safety. That will be evident when you receive your first CintiChem generator from MPI. medi+ 5801 Christie Avenue, Emeryville, CA 94608 For More Information, Please Call (415) 652-7650 Inside California Toll Free (800) 772-2477 •Outside California Toll Free (800) 227-0492

CintiChem " Technetium Tc99m Generators are jointly manufactured by Union Carbide Corporation and Cintichem, Inc. a wholly owned subsidiary of Medi-Physics, Inc.

Volume 24, Number 1 1A GTSK-7HD.8BK THE LASTSHALL BE FIRST TM The Kiftâfflef 1C Series of Xenon Gas Delivery Systems is the most recent Xenon system to be developed yet it is the FIRST in a number of VERY IMPORTANT FUNCTIONS.

FIRST: To deliver a forced breathing system that can duplicate all the functions of a respirator, including PEEPand allows you to study patients with chronic that require breathing assistance and controlled 0, environments.

FIRST: WITHDIGITAL FIRST: WITH REVER RADIOACTIVE CONCEN- SIBLEBREATHINGPORTON A FULLYLEAD LINED ARM. RATION (mCi/L) READ OUT.

FIRST: WITH ELEC TRONIC REMOTECONTROL (OPTIONAL).

FIRST: WITHDIGITAL PRECISION 02 REPLENISH FIRST: WITH A COM MENT THAT ALLOWS YOU PLETELYSHIELDED EXPAN TO STUDY PATIENTS ON IN DABLEINTERFACE. CREASED 0 2 LEVELS.

FIRST: WITHA 150 LITER EXPANDABLE INTER FACE. FIRST: WITHOVER20 FT. OF ACTIVATED CHAR COAL IN A SPECIALLY FIRST: WITH AUTO DESIGNED CARTRIDGE MATIC XENON TRAP ON PACK THAT INHIBITS AND OFF. XENON REDISTRIBUTION WHEN NOT IN USE.

OTHER STANDARD FEATURES INCLUDE: Xenon Trapexhaustport monitor/alarm, low dead space, retractable and REVERSIBLEbreathing port arm, totally mobile, easy open CO 2 and Moisture Trap jars, low breathing resistance, inline Bacteriological Filter, reuse of stored Xenon, and ease and simplicity of operation found in no other unit. TheXENA MA TIC Serieswasdesigned to meet the stringentrequirementsof rCBF.Thesame requirementscan expand your Xenon lung function capabilities. FQR MQR£,NFORMATION> CALL OR WRITE TODA Y:

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2A THE JOURNAL OF NUCLEAR MEDICINE Takethe Mystery out of Isotopie Analysis. Canberra multichannel analyzers simplify your life with instant, error-free solutions at the touch of a button.

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Series 35 Series 10 •Expandable data memory, •Battery powered 1k, 2k, 4k •4096 channels data memory •Full computer control with •ADC 50 MHz, 4096 channel RS232 or GPIBinterfaces conversion gain •The best 100 MHZ ADC in •Self-contained spectroscopy the industry amplifier •Optional push button dose •Self-contained HVPS calibration •5 inch diagonal LCD •Standard one year warranty - extendable to five years CANBERRA Canberra Industries, Inc. 45 Gracey Avenue Meriden, Connecticut 06450 Telephone: 203/238-2351 Two ImagersinOne !

Yes, it's true! department or practice! Each mode has its own contrast control and of course The new 5000C analog/digital Side-by-side comparison of ana the entire unit features IIE's camera from Illinois Imaging log and digital information is a Electronics has a split person snap! The operator simply selects patented electro magnetically ality. It's a nuclear imager. It's a one of several format sizes - and controlled shutter! video imager. In fact, it's the at the flip of a switch the 5000C The real genius of the 5000C is only combination imager will image from a not only what it does. But what available for today's computer- or a computer - on 8 x 10 film. it allows you to do! assisted nuclear medicine

901 South Kay Addison, IL 60101 Phone: (312) 543-4878 Call Barbara Stadman for your local distributor. In which range isGastrin test sensitivitymost important?

normal questionable abnormal The answer is^questionable^

Why? Because values in the "question able" range (150 pg/ml-350 pg/ml) could is only 70 minutes, for fast turnaround. For more information about the value of reflect any of a number of disorders. gastrin testing in the questionable range, Exactly where a value falls within this range or for an evaluation kit, please contact us. can help the physician determine what Call or write Clinical Assays, Division of might be wrong, and what follow-up tests Travenol Laboratories, Inc., 620 Memorial or clinical observations could resolve the Drive, Cambridge, Massachusetts02139. "questionable" diagnosis. Toll free in U.S.: (800) 225-1241. So it is within this elevated range that In Massachusetts: (617) 492-2526. accurate gastrin values can be of greatest clinical significance to the physician. And the GAM MADAB®Gastrin RIA Kit is GammaDab® designed to provide exactly that. Unlike other gastrin kits, its greatest sensitivity is in this critical "questionable" range. Gastrin RIA Kit In addition, our double-antibody gastrin kit is convenient to run. All reagents come Innovating for Life" ready-to-use, with just two pipetting CLINICAL ASSAYS volumes. Total room temperature incubation DIVISION OF TRAVENOL LABORATORIES, INC. 40 100 200 500 1000 GASTRIN CONCENTRATION pg/ml r complete prescribing information consult package insert, a brief surrwifcry of which follows:

Thallous Chloride TI 201 is supplied in isotonic solution as a sterile. Chloride TI 201 as well as other radioactive must be handle gnostic for intravenous administration. Each d appropriate satety measures should be used to minimize radiation 8 1 milliliter and each milliliter contains 2 millicuries of Thallous sure to clinical personnel. Also, care should be taken to minimize radiation ex| Call brat ¡ontime. pH adjusted to 5.0-8.0 with hydrochloric acid and to the patient consistent with proper patient management. or sodium hydroxide Contains no bacteriostatic preservative. Thallium TI 201 is cy clotron produced and is essentially carrier-free. Radionuclidic purity at calibration should be used only by physicians who are qualified by Min time is at least! 1.0°»with less than 1.0% Thallium TI 200.1.0% Thallium 202 and 0.2% ing and experience in the safe use and handling of , and whose experi Lead Pb 203. The concentration ol each radionuclidic contaminant changes with time. ence and training have been approved by the appropriate government «dency authorized to license the use of radionuclides. INDICATION AND USAGE: Thallous Chloride TI 201 may be used in cardiac imaging to define the estent of myocardial infarction. Carcinogenesis. Mutagenesis. Impairment of Fertility No long-term animal studies have been performed to evaluate carcinogenic potential, It may also be useful m conjunction with exercise stress testing as an adjunct in the mutagenicity potential, or whether Thallous Chloride TI 201 affects fertility in males diagnosis ot ischemie heart disease (atherosclerotic coronary artery disease). or females. CONTRAINDICATIONS None known. Pregnancy Category C WARNINGS: I fhen studying patients suspected or known to have myocardial infarc Animal reproduction studies have not been conducted with Thallous Chloride TI 201 tion or ischemia, care should be taken to assure continuous clinical monitoring and It is also not known whether Thallous Chloride TI 201 can cau«»fetal harm when treatment in accordance with safe, accepted procedure. Exercise stress testing should administered to a pregnant woman or can affect reproduction capacity. Thallous be performed only under the supervision ol a qualified physician ar Chloride TI 201 should be given to a pregnant woman only if clearly needed. eguipped with appropria i resuscitation and support apparatus. Nursing Mothers PRECAUTIONS is not known whether this is excreted in human milk. Because excreted in human milk, caution should be exercised when Thallous Chloride General is administered to a nursing woman. ^M Do not use after the expiration time and date (4 days after calibration time) stated on the label. Pediatrie Use ^ Safety and effectiveness in children have not been established. Discard vial after single use. Do not use if contents a ADVERSE REACTIONS: Adverse reactions related to use of this agent have not been The patient dose should be measured by a suitable radioac W.^B»M^_____. -^fl immediately prior to administration. Hot Chloride TI 201 is supplied as a sterile, nonpyrogemc Ideally, examinations using radiopharmaceuticals, especially n in unit dose vials containing 1 milliliter. Each milliliter contains 2 on a woman of childbearlng capability should be performed during the first millicuries of Thallous Chloride TI 201 at calibration lime. Contains no bacterio proximately 10) days following the onset of menses. static preservative. medi+ 5801 Christie Avenue, Emeryville, CA 94608. For More Information, Please Call (415)652-7650. Inside California Toll Free (800) 772-2477. Outside California Toll Free (800) 227-0492. t

That's a lot of hospitals and clinics and it's the num ber of customers we're serving today. It's a source of pride to us because it reflects confidence. Today we operate the largest chain of centralized nuclear pharmacies in the United States. And we want to meet your needs for radiopharmaceuticals and our exclusive services ranging from waste disposal to radiation safety consultation to instrument cali bration as well as many new services continu ally being added. We have a Pharmacy Service Center near you. Call us.

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Kod.iK orffio A/I film

i r\f\\*m '*"* J.UU i /n , . / . »

••• Kodak X-RAY FILM New Kodak ortho M film The speed to nip dot blooms in the bud.

Increasing the brightness of the image on your patterns. The film's orthochromatic sensitivity nuclear medicine monitor can result in undesir matches the phosphor emissionsof blue and able dot "blooming" which diminishes the diag green cathode-ray tubes. Could you ask for nostic value of the ¡mage.The new Kodak ortho more? Perhaps processing in 90 seconds? New M film has the high speed necessary to reduce ortho M film offers that, too. the need for increasing brightness levels, thus Ask your Kodak Technical Sales Represen minimizing dot blooming. Kodak ortho M film tative for a demonstration, or write Eastman is a single-emulsion film with high contrast and Kodak Company, Department 740-B, Rochester, halation control which delivers crisp, sharp dots New York 14650. and clearly defined edges of dot concentration TURNING ENERGY INTO IMAGES

©Eastman Kodak Company, 1981

Volume 24, Number 1 13A LAO STRESS

LAO REDISTRIBUTION

. Thalliummyocardialscintigraphy. Theclearestimagesintheindustry.Inthiscaseit'sdiffuse coronaryarterydiseaserevealedbyTl-201scintigraphyonBaird's SystemSeventy-Seven®gammacamera.Fora betterunderstand ingofBaird'scapabilitiesin nuclearcardiologywriteorcallour NuclearMedicineDepartment.We'llseethatyougetcomplete information,includinganextensivebibliography.BairdCorporation 125MiddlesexTurnpike,Bedford,MA01730. Telephone(800)343-4827, O A l R f^ in Massachusetts(617)276-6500. 137 ill\IJ Certainty in cardiac diagnostics. WEMUSTIMPRESSIT ONYOURMIND.

Teledyne supplies Nal (TI) crystals to many Full Range. Crystals of various shapes and sizes to hundreds of satisfied customers. Why do they come suit most applications. back to Teledyne Isotopes? Because, in an industry Fast Delivery. On-time service makes Teledyne that has always been precise and demanding, they know Isotopes the first supplier for many O.E.M.'s. they can depend on our: Low Prices. 20-30% less expensive than published list •Crystal Purity. K content of < 1.0 PPM. prices of other crystal manufacturers. •Reliability. The hermetic seal is designed Face it. . .there's little difference in quality to last for years. . .and does. being manufactured •Performance. Resolution for today. most solid crystals is down to 7.0-7.5% for Cs-137; lower resolutions are available at a premium price. For well-types and hole-through, we offer the best resolution. •Stability. We use the best Your important choices are P.M. tubes in the areas of delivery and available. price. Contact Teledyne Isotopes for a price list or quotation, and then check our delivery.

^TELEDYNE ISOTOPES 50 Van Buren Ave. Westwood, NJ 07675 (201)664-7070 Telex 134-474 FOR NEW AND RE-CORED For increasing both the resolution and COL IMATORS Our computer design and manufacturing the sensitivity of nuclear medicine capability achieves results you can see imaging, look first to the collimator- and Collimatlon, Inc. in product quality and cost. And as part of your camera We've provided the latest advances in collimator or scanner system, a new or re-cored collimator from engineering to nuclear medicine professionals nation Collimation can help you achieve a clinically significant wide for over ten years. Today, we produce a wide variety improvement in spatial resolution and image contrast. of precision collimators - from large field, medium So for enhanced nuclear medicine imaging that can energy to standard field, insert-type- that can be readily be clinically useful and economically prudent, focus incorporated into your imaging system. in on Collimation. COLLIMATION, INC. For more information, contact: Collimation, Inc., 241 Midland Avenue, Montclair, NJ 07042 •(201)575-9598 SIEMENS

Comprehensivenuclearimaging systemsfor wholebodystudies

Siemens nuclear imaging systems To protect your investment, all bring new levels of efficiency and Siemens systems are offered with flexibility to whole body studies. comprehensive service programs backed by one of the industry's Our ZLC 370/750 camera series with whole body table, and our ROTA largest technical service organiza CAMERA system, perform whole tions dedicated to nuclear medicine. body studies with minimal space and For additional information on how time requirements. Ease of operation Siemens comprehensive nuclear im assures rapid patient throughput. aging systems can fulfill your re quirements, contact your local ZLC detectors ensure high quality representative or: bone and studies by providing Siemens Medical Systems, Inc. unsurpassed uniformity and resolu Nuclear Medicine Division tion. Application of these versatile 186 Wood Avenue South cameras can be expanded for SPECT ? Iselin, NJ 08830. (201) 321-3400. studies.

Meeting your diagnosticrequirements...intothe future. uo/uwni «io573 CardiacStress Here is EDO'sHi-LowModel 8430 UL Listed Imaging During Stress —Upright or Supine. Cardiac Stress All Digital Readout Provides Error-Free Indications. Fully Adjustable Ergometer Position and Angle to TestingSystem Fit Patients of any Size. withthese Designed to be Used with Standard View and Large Field Cameras. features: Low Density Table Top. Posterior Viewing with any Camera. Controls Conveniently Located on Separate Console which can be Positioned anywhere. Heart Rate Control of Workload. Can Accept ECG and Computer Heart Rate Signals. Patient Monitors Own Speed, Thus Eliminating Unnecessary Directions. Rugged Construction. Visual Heartbeat Indicator, Aural Indication Available Through Front Panel Switch. Can be Calibrated in the Field. Automatic Load Drop-out at Low Pedal Speed. Table can be used for General Imaging Elapsed Time Clock Updated Every Six Seconds. Stands on Four Legs —Retracting Wheels.

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298 on-board computer and high resolution images. Anywhere. NewDataMo ComputerizedMobileCamera SystemfromPickerInternational. Micro Z and ACEâ„¢Imaging. . I Automatically Positioning. calibrates the Single-sided yoke. detector to allow Five axes of detec Asymmetric Contrast Enhancement .- tor motion. 13-inch Color Monitor. Image Data High resolution Programmer. image and ECG Analog and digital image multi- display. formatting. Integrated 16 bit computer. High capacity Winchester disc technology. Plus floppy disc drive for patient data.

Picker International's new Data Mo Medicine Department to take the strain is a completely integrated mobile camera off peak workload periods. and computer. Its mobility brings all the Call your local Picker International benefits of high resolution imaging and representative to get all the information quantitative analysis right to the patient. about the computer power of Data Mo Fully supported software is available for with its high resolution images. Or write: your clinical setting. Use the Data Mo in Picker International, Nuclear and Ultra intensive care, cardiac care unit or emer sound, 12 Clintonville Road, P.O. Box 99, gency room. Even right in the Nuclear Northford, CT 06472, (203)484-2711. PICKER INTERNATIONAL Thereare32reasons whyApexProcessors arebetterthananyother NuclearMedicine DataSystems. ThisisreasonNumber theworld'sMakingmostapexpowerful NMprocessor tookthousands ofman-hours. Youcanlearntooperateit inone.

elscint's apex line

Elscint has prepared a full-color booklet detailing all 32 reasons. Contact us today for your personal copy. Despite the sweeping clinical redundant steps by typing in 2- or range and power of Apex systems, 3-letter MNEMONIC MODE they are extremely easy to operate. commands. New users can learn to operate them MACRO-PROGRAM MODE is immediately in fast, easy MENU fastest of all: any of 28 MODE, where commands are listed in pre-programmed protocols can be multiple-choice format, and advanced t activated by touching a single key. step by step. Experienced users can eliminate ApexProcessors:32WaysBetter!

i

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UH O 1.ACQUISITION e.i/o 7.HHTOGMN PROCESSING ______8.CLINIC*. STUDIO 4. PRESETPROTOCOLS 9 UTILITIES s.nwc PROCESSING

ElscintInc. ElscintEuropeanOperations, 930 Commonwealth Avenue, 40RueJeanJaurès, Boston, MA 02215,U.S.A. 93170Bagnolet,France. Call Toll Free: 800-343-9504. Tel: 101/362.13.05. Add InventoryControl and NRC Record Keeping to your Doseoalibrator System

ISOTRONISOCORD INVENTORY CONTROL COMPUTER AUTOMATIC DATA PRINTER The RADXIsotron isthe original unit that The RADX Isocord produces a hard copy print qualifies as a nuclear medicine inventory out in triplicate for all record keeping needs; control computer. It keeps track of all (and will by patient name, and selected . program 20 preselected ) radio Addition of the Isocord will complete your Pharmaceuticals in different chemical forms, dosecalibrator systemfor all necessary and provides inventory status (continuously information including NRC or state record subtracting decay) on each radio keeping requirements. RADX isthe firstto pharmaceutical. Italso offer anything like it at any performs dose where near itsprice. ivolume calculations Boththe Isotronand in present and the Isocord are totally variable compatible with your future time and existing dosecalibrator. date. Computer Complete patient and institution Fogramming skillsnot identification - plustime and date Pharmaceutical Identification required. Write,or Total vial activity prior to removal of call RADXtoday: dose - constantly updated for 713/468-9628 decay and previouswithdrawals Concentration/ml Patientdose Volume to administer - automatically calculated Informationprovided in either,Curriesor Becquerels.

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o cardiac stress system that does more and costs less. Designed for exercise imaging SPECIFY MODEL 056-180 IN YOUR INFORMATION REQUEST

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FOR COMPLETE INFORMATION WRITE OR CALL— Atomic Products Corporation ATOMLAB DIVISION •ESTABLISHED 1949 P.O. BOX 657 CENTER MORICHES, NEW YORK 11934 USA (516) 878-1074 TWX #510-228-0449 Something New from Something Old ND62T PROBE SYSTEM, INCLUDING A 1024 CHANNEL MULTICHANNEL ANALYZER Thyroid uptake tests have been done for decades, and multichannel analyzers have been available for decades. Now, however, the ND62T thyroid probe system marries both these proven techniques. A 2"x2" well crystal is used in a design which makes possible a whole new range of clinical applications. A unique feature is a counterbalance stand for quick, simple, accurate positioning. Priced less than $10,000—write or phone for product brochure. Medical Products ND Medical Products * 221 Felch Street •Ann Arbor, Michigan 48103 •Telephone (313) 665-9777 Subsidiary of Cable: NUDATA Telex 28-2416 Nuclear Data Inc. •Golf and Meacham Roads •Schaumburg, Illinois 60196 •Telephone (312) 884-3600 TM PARAMEDICAL

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PA RAMEDICAL INC. 57°PLEASANTSTREET WATERTOWN,MASSACHUSETTS021/2 617 926-8110 Cardiac STRESS SYSTEMS SINGLE at almost EMISSION COMPUTED 1/2PRICE TOMOGRAPHY and Other Selected Computer Topics of others! • Edited by Ronald R. Price, Ph.D., David L. Gilday, M.D., and Barbara Y. Croft, Ph.D.

Based on the Tenth Annual Symposium on the Sharing of Computer Programs SUPINE SYSTEMS and Technology in Nuclear Medicine, January 1980, this book describes a variety of SPECT techniques, including angled, parallel-hole, and seven-pinhole collimators; Pho/Con instruments; and Fourier techniques.

Computer analysis of cardiac studies, data acquisition and storage methods, Anger camera evaluation, and whole- body counting are explored. In addition to a review of various algorithms and UPRIGHT SYSTEMS currently available computer systems, SPECT offers a performance comparison of instruments. Sponsored by the Computer Council of the Society of Nuclear Medicine, Single Photon Emission Computed Tomography and Other Selected Computer Topics provides current research of clinical CONVERTIBLE SYSTEMS interest to nuclear medicine physicians, physicists, and computer specialists. Compatible with every major ergometer on the market 244 pp. Illustrated. ISBN 0-932004-06-7. Modular designs simplify system LC 80-52817. List price: $27.00; SNM updating member price: $18.00. Add $2.50 per book Heavy-duty welded -steel frames for postage and handling. Purchaseorder for extra stability or prepayment in U.S. funds drawn on a U.S. bank is required.

S Medicai Products Order from: Book Order Department ND MEDICAL PRODUCTS •221 FELCH STREET The Society of Nuclear Medicine ANN ARBOR, MICHIGAN 48103 •(313)884-3600 475 Park Avenue South New York, NY 10016. SUBSIDIARY OF NUCLEAR DATA INC. •GOLF & MEACHAM RDS. SCHAUMBURG, ILLINOIS • (312)884-3600

28A THE JOURNAL OF NUCLEAR MEDICINE OVER 200 REASONS Video Film THAT YOU ARE RIGHT!! FORMATTERS THYROID UPTAKE at almost SYSTEMS 1/2PRICE EXCLUSIVES 1 "STATE OF THE ART" SUPER STABLE SPECTROMETER/ SCALER SYSTEM ALLOWS MANUAL OR AUTOMATIC OPERATION of others! 2 DUAL DETECTOR SELECTION SYSTEM UTILIZING INDIVIDUAL PREAMPLIFIERS ALLOW INSTANT DETECTOR CHANGEOVER FROM PROBE TO WELL WITHOUT RECALIBRATION. 3 UNIQUE UNIVERSAL SWIVEL MOTION ENABLES YOU TO ACHIEVE ANY PATIENT/DETECTOR GEOMETRY AND POSITIONING NOT POSSIBLE WITH OTHER SYSTEMS 4 PRECISE COUNTER-BALANCE OF THE DETECTOR ARM. ALLOWS FINGER-TIP POSITIONING AND ELIMINATES THE USUAL "EVER- FAIL" LOCKS. 5 DOUBLE CABLE DETECTOR SUPPORT ELIMINATES THE DANGER OF A PATIENT ACCIDENT. 6 TOTAL MOBILITY AND STORAGE IN AN AREA OF LESS THAN 24" x 24" ADD VERSITILITY TO THE SYSTEM.

ADD THAT HALF DOZEN REASONS TO THE MORE THAN 200 SATISFIED USERS OF ADC MEDICAL'S 111S AND 111S2 THYROID UPTAKE SYSTEMS AND YOU KNOW YOU HAVE MADE THE RIGHT CHOICE!

FOR ADDITIONAL INFORMATION tftedkcd CALL OR WRITE US 400 SMITH STREET.FURMINGDAIE.NY.11735 (516) 752 9686

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ND Medical presents a family of video film formatters. These include a one-on-one imager, a six-on-one imager, and a nine-on- one imager. The ND Medical Video Format ters are in compact, space-saving cabinets and are considerably less expensive than all other commercially available formatters. It's terrible, but true, that children this young have learned to We offer the most complete line of nuclear say this sentence. At St. Jude stress equipment in the industry. Complete Children's Research Hospital we are literature on request. trying to find the cause, cure and, ultimately, the prevention for cancer so no one will ever have to say these words again. I\D Medical Products Please support the research at St. ND MEDICAL PRODUCTS •221 FELCH STREET Jude. For more information, please ANN ARBOR, MICHIGAN 48103 •(313)884-3600 write St. Jude, P.O. Box 3704, Memphis, Tennessee 38103, or call SUBSIDIARY OF 1-800-238-9100. NUCLEAR DATA INC. •GOLF & MEACHAM RDS. SCHAUMBURG, ILLINOIS • (312)884-3600

Volume 24, Number 1 29A SNM offers fhree new AUDIOVISUALS

Radiopharmaceuticals for , Spleen, Bone Marrow, and Pancreas Imaging —Henry M. Chilton/SI-25 Presents basic radiopharmacology and pharmaceutical chemistry for radiopharmaceuticals used in liver, spleen, bone marrow, and pancreas imaging. Unit includes information on radiopharma- ceutical biodistribution properties and factors that cause poor imaging. 77 slides; 43-min audio

Biological Effects of Low-Level Radiation—Richard I. Witcofski/SI-26 Provides up-to-date information about the effects of low-level radiation exposure on humans. This program examines the difficulties in detecting biological effects at low-dose levels and compares the risks of low-level radiation exposure to other risks of life. 80 slides; 59-min audio

Technetium Radiopharmaceuticals for Brain, Lung, and -Pool Imaging —William C. Eckelman and Stanley M. Levenson/SI-27 Features a detailed discussion on Tc-99m, including the Mo-99/Tc-99m generator, the chemistry of technetium, and the labeling mechanisms of the various technetium radiopharmaceuticals cur rently used in nuclear medicine. 59 slides; 39-min audio

Audiovisuais come complete with expert narration and carefully selected supporting visual materials. Consisting of sequentially mounted 35 mm slides and standard audio cassettes, each program forms a complete teaching package suitable for individual or group instruction. Units can be operated manually or on a system that advances automatically. A complete list of SNM audiovisual is availableORDER uponFORMrequest.

COST PER UNIT: $55.00 for members; $75.00 for non- Please send me (specify quantity): members. Price includes postage and handling for orders SI-25 . SI-26 SI-27 originating in the US and Canada. Elsewhere add $5.00 per unit for shipping. If the Society cannot identify purchaser as Type of audio cassette preferred: D manual D automatic a member, it will not accept order with member price. Prices . Total Amount Enclosed are in US dollars and subject to change without notice. Please Print: Prepayment required in US dollars drawn on US banks only. No foreign funds accepted. For payments made in US dollars, Name but drawn on a foreign bank, add $1.50 bank processing fee for Canadian bank drafts or $20.00 for all other foreign drafts. Address (including zip code) Send check or purchase order to address listed below.

SPECIAL VOLUME DISCOUNT (until further notice)!! Buy 10 units or more as a single order and receive a 10% discount.

SOCIETY OF NUCLEAR MEDICINE 475 Park Avenue South, New York, NY 10016

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offers you... NUCLEAR MEDICINE REVIEW SYLLABUS Prepared by more than 50 noted authorities in the field, this volume presents a comprehensive over view of the major scientific and clinical advances that have RADIOPHARMACEUTICALS AND occurred in nuclear medicine over the last decade. Chapters include RADIOPHARMACEUTICALS II Radiopharmacology, Instrumen Proceedings of the 1st and 2nd tation, Radiation Effects and Pro International Symposiums on tection, Cardiovascular, Central Radlopharmaceutlcals Nervous System, Endocrinology, These 2 volumes contain a series of Gastroenterology, Genito-Urinary informative papers that examine the System, Hematology, Oncology, present state of the field of radio- Pulmonary, Radioassay, and . Chapters cover such Skeletal System. Softcover; 6*9; topics as the design, development, 630 pp; $30.00. Now into its second preparation, regulation, and clinical printing! use of radiopharmaceuticals. Also discussed are organic and inorganic radiopharmaceuticals, functional SINGLE PHOTON imaging, RIA, pharmacokinetics, and EMISSION COMPUTED various body systems. TOMOGRAPHY Radiopharmaceuticals: Hardcover; 7*10'/2;571pp; $30.00. Radiopharma This book presents an overview of ceuticals II: Softcover; 8V2*11,857pp; single photon emission computed $40.00. SPECIAL BONUS OFFER: tomography and includes Purchase both as a set for $50.00. numerous papers that describe and evaluate specific systems and techniques. Papers cover such topics as Anger cameras, seven- pinhole and slant-hole collimators, FUNCTIONAL MAPPING OF brain, cardiac, and gated blood- ORGAN SYSTEMS AND OTHER COMPUTER TOPICS pool studies, and the BICLET and Sponsored by the Computer and Instrumentation Councils, this book contains 25 papers that high SPECT systems. Physicians, light important areas of computer software development in nuclear medicine, such as functional physicists, and computer spe mapping and imaging of organ systems. Other important aspects of computer development and cialists will find the current re use—background subtraction, computer tomography, and image display techniques—arealso search of clinical interest. Soft- included. This volume is indispensable to physicians, medical research scientists, and computer cover; 6*9,252 pp; $18.00mem specialists. Softcover; 6*9; 272 pp; $19.00members;$28.00non-members. bers; $27.00 non-members.

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CURRICULUM GUIDE FOR NUCLEAR MEDICINE TECHNOLOGISTS Arranged in 25sequential units containing an overview, outline, and objectives, this guide features topics recommended for a 1-year nuclear medicine technology program. Two sections describing associate and baccalaureate degree programs are included. The book serves as a model for nuclear medicine technology educators to develop or expand their curricula. Loose-leaf; 8V4x 11;336pp; $50.00members;$60.00non-members.

CLINICAL EVALUATION METHODS GUIDE This guide is designed to aid allied health and nuclear medicine technology educators in developing appropriate assessment instruments for evaluating student performance. The 6 assessment tools examined include: checklists, rating scales, anecdotal records, critical incident technique, questionnaires, and data forms. Softcover; ñVix 11; 72 pp; $15.00members; $18.00non-members.

And look for our 3 new books: LOW-LEVEL RADIATION EFFECTS: A FACT BOOK; NUCLEAR MEDICINE SCIENCE SYLLABUS, second fully revised edition; and DIGITAL IMAGING: CLINICAL ADVANCES IN NUCLEAR MEDICINE.

ORDER NOW! Prepayment required in US funds drawn on US banks only. Add $1.50 processing fee for US dollars drawn on Canadian banks; $20.00 on banks outside US and Canada. Also add $2.50 postage and handling for each book ordered. Make checks payable to: The Society of Nuclear Medicine, at 475 Park Avenue South, New York, NY 10016. (212)889-0717. Prices are subject to change without notice. PLACEMENT

ASSISTANT OR ASSOCIATE DIRECTOR OF NUCLEAR MEDICINE PHYSICIAN/DIAG RADIOPHARMACY. Applications are invited NOSTIC RADIOLOGIST. Board Certified with POSITIONS OPEN from radiopharmacists or pharmacists with sufficient imaging fellowship in Nuclear Medicine. Prefer experience in radiopharmacy for the above position ABNM certification also. To join 9 Radiologists in NUCLEAR MEDICINE TECHNOLOGISTS. available as of January 1, 1983. The degree required subspecialty-oriented practice in 611-bed general Staff and supervisory positions available in hospitals is B.S. or higher. Must be a registered pharmacist teaching hospital. Send curriculum vitae to R.L. nationwide. Tell us your geographic preferences, or be eligible for licensure in the State of New Waldron, II, M.D., Director of Radiology, Rich- career objectives, arid personal needs. Our health Mexico. Must have managerial experience and may land Memorial Hospital. 3301 Harden Street, care consultants will work with you to find your next be required to work weekends, emergencies, and Columbia, SC 29203. position. All positions fee paid. Contact: Chuck early shifts (5 a.m.). Be responsible for management Snyder, Dunhill of Orlando, Inc., 2699 Lee Road, of the radiopharmacy service and teach radio- Suite 270, Winter Park, FL 32789; (305)6284227. pharmacy to students and residents. Academic rank NUCLEAR MEDICINE TECHNOLOGIST. and salary will be commensurate with experience. Position now available for an experience/registered Send resume to G.B. Saha, Ph.D., Director of Ra Nuclear Medicine Technologist in a progressive, Applications welcomed from BOARD- diopharmacy, College of Pharmacy, University of newly constructed, and newly equipped department. CERTIFIED GENERAL RADIOLOGISTS with New Mexico, Albuquerque, New Mexico 87131 or Extensive computer capabilities, tomographic imag special interest in Nuclear Medicine at Saint Paul- call (505)277-6104. UNM is an Equal Opportunity ing (emission tomography), as well as newly con Ramsey Medical Center. U of M teaching appoint Employer. structed and equipped nuclear medicine research ment. Salary negotiable. Start immediately. Contact facilities. Beautiful, recreational & mountain envi P. L'Heureux, MD, Chief, Department of Radiol ronment. An equal opportunity, affirmative action ogy, Saint Paul-Ramsey Medical Center, 640 Jack Applications are solicited for the position of employer. Contact: Naomi Alazraki, M.D., or Ed son Street, Saint Paul, MN 55101. (612)221-3793. NUCLEAR MEDICINE PHYSICIST/RADIA Greenberg, CNMT, Nuclear Medicine Service, Vet TION SAFETY OFFICER, at the Martinez, Cal erans Administration Medical Center, 500 Foothill ifornia Veterans Administration Medical Center Blvd., Salt Lake City, UT 84148. (801)584-1266. NUCLEAR MEDICINE TECHNOLOGISTS until March 15, 1983. This is a full-service needed nationwide! Attractive locations, excellent 450-bed teaching hospital closely affiliated with NUCLEAR MEDICINE TECHNICIAN. Our salaries, career opportunities. No cost to you. Con the University of California, Davis, and located expanded facility is seeking a full-time registered tact Ruth Knight, Nationwide Recruiters, 3710 only 30 miles from San Francisco. Candidate must be currently proficient in Nuclear Medicine or Registry eligible Nuclear Medicine : ¿clinician Landmark Dr., Suite 111, Columbia, SC 29204. for a Monday through Friday day shift |. ition. The (800)845-0992 or (803)738-1790. Physics and also be able to manage a radiation safety program for a complex medical center with selected candidate must meet Registry requirement full academic medicine programs. Position carries (ARRT or NMTCB) for Nuclear Medicine technol NUCLEAR MEDICINE RESIDENCY. The full civil service benefits and status. US citizenship ogy. A stimulating work atmosphere is combined with pleasant working conditions in a rural area Nuclear Medicine Division, Department of Radiol is required. Contact Charles Barnett, M.D., Nu which is conveniently close to the larger metro ogy of the University of Texas Medical Branch, clear Medicine Service, VA Medical Center, 150 Galveston, TX (1,200 hospital beds) invites applica Muir Road, Martinez, CA 94553. (415)228-6800, politan areas. Please send resume to: Personnel Di tions for its two-year residency training program. ext. 381. The VA is an Affirmative Action/Equal rector, Lapeer County General Hospital, 1375 North Main St.. Lapeer, MI 48446. An Equal Opportunity The program is approved by the Accreditation Opportunity Employer. Council on Graduate Medical Education and satisfies Employer. the residency requirements of the American Board of Nuclear Medicine. Comprehensive training is DIRECTOR OF NUCLEAR MEDICINE, NUCLEAR MEDICINE TECHNOLOGIST. provided by a large staff that offers both a broad Seattle VA Medical Center. Full affiliation with Position now available for an experienced Nuclear clinical experience and strong basic science instruc the University of Washington. Associate professor Medicine technologist certified by SNM or reg tion. Areas of experience include full range of pa level preferred. Excellent clinical facilities and istered technologist in a private progressive out tient care services (diagnostic and therapeutic), im outstanding research opportunities with established laboratories and personnel in single-photon emis patient Nuclear Medicine laboratory in a large city aging procedures, image data processing and com in a large medical center in the Sun Belt. Knowledge puter technology, nuclear cardiology, laboratory sion tomography, nuclear cardiology, computer of radioimmunoassay, imaging, computer, and nu studies (in vitro and in vivo) and opportunities for image processing, and tumor specific antibodies. clear cardiology in addition to supervisory, admin research. Excellent salary and benefits package. NMR pilot study. Available July 1983. Contact: istrative, and teaching experience required. Please Contact Director, Nuclear Medicine Division, Wil B. Nelp, M.D., Division of Nuclear Med send resume to: Box 102, Society of Nuclear Med Department of Radiology, University of Texas icine, RC 70, University Hospital, 1959 N.B. icine, 475 Park Ave. So., New York, NY 10016. Medical Branch, Galveston, TX 77550. AC Pacific, Seattle, WA 98195. Equal Opportunity (713)765-2926. UTMB is an Equal Opportunity/Af Employer. firmative Action Employer. NUCLEAR MEDICINE PHYSICIAN. Ex perienced Nuclear Medicine physician in expanding RESEARCH ASSISTANT. A specialized re progressive private in vivo and in vitro NM out NUCLEAR MEDICINE TECHNOLOGIST. search position is available in Medicinal Nuclear patient laboratory. Applicant should be board cer Cottonwood Hospital Medical Center, a non-profit Chemistry in a large medical center. The research tified by ABNM or board eligible in Nuclear Medi 243-bed secondary care facility is seeking registered principally involves the design synthesis and phar cine with preferably two years internal medicine res macological evaluation of labeled radio- or registry eligible technologists. Located along the idency training. Medical school association or af Wasatch Front, excellent benefits and competitive pharmaceuticals for use in neurological central filiation possible if desired. Please send resume to: salary are offered. Submit resume to: Personnel, nervous system research. $20,000 per year. Re Box 103, Society of Nuclear Medicine, 475 Park Cottonwood Hospital Medical Center, 5770 E. 300 quired Ph.D. in organic chemistry. Send resume to Ave. So., New York, NY 10016. S., Salt Lake City, UT 84107. (801)262-3461. MESC, 7310 Woodward Avenue, Room 415, Equal Opportunity Employer. Detroit, Ml 48202. Refer to #38042. NUCLEAR MEDICINE TECHNOLOGIST. Im mediate opening for registered technologist in ac NUCLEAR MEDICINE RESIDENCY NUCLEAR MEDICINE TECHNOLOGIST. credited 200-bed hospital in beautiful Northern Cal Available. luly 1983. Two-year accredited affiliated Full-time position available at South Miami Hos ifornia. Active department provides imaging (includ program. 2000+ beds, multihospital, physician and pital, Miami, Florida, for a registered Nuclear ing nuclear cardiology), in vivo and . Ap scientist faculty-to-student ratio of 2:1. Compre Medicine Technologist. At our 528-bed communi propriate experience required. Competitive salary hensive training in the basic sciences, radiophar- ty hospital, we perform a full range of diagnostic and excellent benefit program. Send resume to: Per macy, computer technology, patient care services, imaging procedures including progressive Nuclear sonnel Director, Mercy Medical Center, PO Box and research. Located in the Sunbelt in one of Cardiology imaging. We offer excellent salaries, 6009, Redding, CA 96099-6009. EOE. America's four "unique" cities, within an easy an impressive benefits package, and relocation drive of the Texas Gulf Coast, Mexico, and the love assistance. Please submit your resume or call ly Texas Hill Country and Big Bend areas. Contact collect. Debbie Brennan, Employment Assistant, NUCLEAR CARDIOLOGY TECHNOLOGIST. Ralph Blumhardt, MD, Department of Radiology, South Miami Hospital, 7400 SW 62 Avenue, S. Private. 520-bed, teaching and university-affiliated University of Texas Health Science Center, San An Miami, Florida 33143. Tel: (305)662-8116. medical center is currently seeking an individual for tonio, TX 78284. (512)691-7265. noninvasive section of its Heart Cath. Lab. Position available due to departmental expansion. Must be NUCLEAR MEDICINE SUPERVISOR. A a graduate of an AMA-approved program in Nuclear NUCLEAR MEDICINE. Full-time position avail leading pediatrie specialty hospital in the Mid Medicine with an ARRT and/or NMTCB registra able for board certified or eligible Nuclear Medi west is seeking an ASCP or ARRT registered tion or eligibility. Minimum of one year hospital/ cine Physician at West Roxbury Veteran's Admini Nuclear Medicine Tech to coordinate and super nuclear cardiology experience preferred. Salary stration Medical Center. This acute care medical vise dept. activities. This is a fast paced dept. commensurate with experience. We offer an attrac center is a teaching affiliate of Harvard Medical offering a fresh approach to pediatrie imaging with tive benefits package including educational School. Demonstrated interest in clinical work, a wide range of clinical procedures. Candidates assistance, group insurance, pension plan, credit teaching, and investigation required. Salary and must have at least 3 yrs. Nuclear Medicine exp. in union, progressive paid leave, and scheduled merit faculty appointment dependent on qualification. cluding some supervision. Send resume including increases. Write or call collect Barbara Ann White, Send curriculum vitae to: Donald E. Tow, M.D., salary history to: Employment Supervisor, Mil Personnel Dept., Crawford W. Long Memorial Chief Nuclear Medicine Service, VA Medical waukee Children's Hospital, 1700 W. Wisconsin Hospital of Emory University, 35 Linden Ave., Center. 1400 VFW Parkway, Boston, MA 02132. Ave., Milwaukee, WI 53233. An Equal Oppor N.E., Atlanta, GA 30365. (404)8924411, ext. 532. An Equal Opportunity/Affirmative Action Employer. tunity Employer. An Equal Opportunity Employer.

Volume 24, Number 1 37A PHYSICIST FELLOWSHIPAND RESIDENCYPROGRAM Position open for recently expanded section in Univer BAYLORCOLLEGEOF MEDICINE sity Hospital. Required: Experience with computer use NUCLEARMEDICINESECTION in cardiac functional evaluation and/or high level com Baylor College of Medicine is now accepting applications for petence in image processing techniques. Opportunity residency and fellowship positions for the 1983-84 academic for developmental work in Nuclear Cardiology and year. The residency program includes training in two large Digital Radiology. nuclear medicine laboratories, St. Luke's Episcopal Hospital- Send C.V. to: Dan G. Pavel, MD, University of Il Texas Children's Hospital-Texas Heart Institute joint facilities linois Medical Center, 1740 W. Taylor Street, Rm. and Ben Taub General Hospital. 2500, Chicago, IL 60612 Residency training encompasses the full spectrum of nuclear AN EQUAL OPPORTUNITY EMPLOYER medicine procedures, both in vivo and in vitro, in pediatrie and adult inpatients and outpatients. Instruction includes clinical nuclear medicine, radiopharmacy, radioimmunoassay, and basic sciences, as well as experience with computer ap plications and tomographic imaging. NUCLEAR STAFF TECHNOLOGIST Fellowships with emphasis on cardiac and pulmonary disease Advanced Nuclear Medicine Department in South Florida hospital has excellent are availablein associationwith the Texas Heart Institute. With opportunity lor Registry Eligible or Registered Nuclear Medicine Technologist. University Community Hospital seeks individual to perform imagery procedures mobile capabilities and a large population of critically ill pa in modern 209-bed acute care facility. tients (total hospital beds, 1250;intensive care beds, 190)there DEPARTMENT OVERLAY INCLUDES: is ample potential for participation in research projects related Instrumentation: 3 Camera Imaging Stations to cardiovascular, pulmonary, and critical care medicine. Siemans ZLC Whole Body Siemans LFOU Whole Body Requests for further information should be directed to: Siemans General Purpose Station Full MDS A* Computer Facility: John A. Bardine, MD, Chief Performing all phases of Nuclear Computerized Cardiology and Computer enhanced routine Nuclear Medicine procedures. or Paul H. Murphy, PhD, Training Coordinator Computerized Dose Calibrator—for Hot Lab facility Nuclear Medicine Section, Department of Radiology This is a permanent, full-time position offering competitive salary, On Call pay, Baylor College of Medicine progressive PTO plan and an excellent benefit package. Interested individuals are invited to contact: Personnel Department, University Community Hospital, Houston, Texas 77030 7201 N. University Dr., Tamarac, FL 33321, (305)721-2200, ext. 460. Equal Opportunity Employer

PHYSICIST NUCLEAR MEDICINE A faculty level position is available for a scientist with background at the Doctoral level in Physics, Radiation Physics, Electrical Engineer ing or related field. NMR Applicants should have an interest and experience in teaching, re search and practical aspects of Nuclear Medicine Physics and Instrumentation. Facilities include a digital electronics laboratory, DEC 1103, Varian SYMPOSIUM V74, MDS A2 and Technicare VIP imaging systems, SPECT and PIPER instrumentation; staff: 5 physicians, PhD chemist, computer engineer, and technologist. CERROMAR BEACH, Send statement of interests and curriculum vitae to: StanleyJ. Gold smith, M.D., Director, Andre Meyer Department of Physics-Nuclear PUERTO RICO Medicine, Mt. Sinai Hospital, New York 10029. AMERICAN COLLEGE OF An Equal Opportunity Employer NUCLEAR PHYSICIANS ANNUAL MEETING MARCH 9-13, 1983 Laboratory Procedures Update 12TH TRAINING COURSE ON For program information contact: HORMONAL ASSAY TECHNIQUES OF THE ENDOCRINE SOCIETY American College of Nuclear Physicians The course will cover all types of methodologies currently employed Suite #700 in assaying hormones in biological fluids, for both experienced and in experienced investigators. The program will cover manual radioim 1101 Connecticut Avenue, N.W. munoassay, nonisotopic assay, cytochmeical bioassays, methods and the application of HPLC to the separation, puri Washington, D.C. 20036 fication, and measurement of hormones. (202)857-1135 Boston, Massachusetts March 21-25, 1983 For applications and information, write to Nettie C. Karpin, The Endo crine Society, 9650 Rockville Pike, Bethesda, MD 20814.

38A THE JOURNAL OF NUCLEAR MEDICINE CAREERS IN NUCLEAR MEDICINE The University of Texas Medical Branch Would understandinghow to use radioisotopes G alveston Island help your career? Join the expanding Nuclear Medicine staff of Texas' 1200-hed teaching hospital complex. A full complement of physicians, scientists, educa If so, plan to attend a two-week laboratory- tors and technical staff operate a progressiue oriented course on: facility. Positions Now Available! Radioisotope Techniques in Research & Development RADIOPHARMACIST/CLINICAL RADIOCHEMIST April 11-22, 1983 or August 15-26, 1983 Combines clinical practice, research and teaching in a large and active university nuclear medicine division, You will learn how to safely use radionu- q. Ph D.. prefer BS in pharmacy clides as tracers and radiation sources in your work. This course provides 80 basic science NUCLEAR MEDICINE training hours required for licensing. TECHNOLOGISTS For more information, telephone 8:00 a.m. to Performs clinical procedures in radiopharmacy, RIA 5:00 p.m. Eastern: lab or imaging and function section. Req. assoc. 800-362-5555 degree or equiv. exp. & cert. elig. Prefer exp. 615-576-3434 Benefits incude 15 days paid vacation, health FTS. 626-3434 and dental insurance, state contributions to or write: Sofia/ Security and no state income tax! Registrar, Professional Training Programs Contact Oak Ridge Associated Universities i Huay D. Barnett. Ed D P.O. Box 117 UTMB Oiv. of Nuclear Medicine R-G Oak Ridge, TN 37830 Galveston. TX 77550 or call collect: (713) 765-2926 EO M F H AA

Position Open Eastern North Carolina University of California at Los Angeles (UCLA) School of Medicine NUCUEAR MEDICINE Applications are invited to fill a tenured endowed professorship call the JENNIFER JONES SIMON CHAIR IN BIOPHYSICS within the Department of Radiological Sci TECHNOLOGIST ences at the UCLA School of Medicine. The endowment will be used to support the appointee's research which should be focussed on both the normal and abnor mal functioning of the human body involving, at least initially, the application of the Pin COUNTYMEMORIAL HOSPITAL,a nuclear medicine technique of positron emission tomography. growingregionalmedical centerinGreen Highest priority will be accorded to applicants who have helped develop or have ville,N.C.,has an immediate opportunity utilized emission tomographic and other comparably promising methods in nuclear for a Nuclear Medicine Technologist. medicine in the field of basic and/or clinical neuroscience research and who have demonstrated some of the potential that these methods may have for a better under Qualified applicants willbe AARTcertified standing of nervous and mental . The Jennifer Jones Simon Professor is expected to qualify for appointment at the higher levels of the Full Professorship. or eligible to work in an expanding radi Applicants should forward a resume or curriculum vitae and the names of at least ology department.Dayshiftpositionavail three referees to the Search Committee Chairman: Dr. Carmine D. Clemente, Direc able. tor, Brain Research Institute, UCLA School of Medicine, Los Angeles, California 90024. The University ol California is an Equal Opportunity/Affirmative Action Employer. SalaryIscommensurate withexperience. Pin COUNTYMEMORIALHOSPITALoffers a full range of employee benefits and pleasant working conditions. Our loca tion in Greenville,NC assuresan excel lent personal lifestyle with nearby beaches and mountains, seasonal cli RESIDENCY IN mate, and a vareity of cultural activities. For more information and immediate NUCLEAR MEDICINE consideration, call or send resume to: Two-year approved program offering broad clinical experience in Employment Office (919) 757-4556 cluding tertiary care and community hospitals, oncology and pediatrics, ultrasound and CT, strong basic science teaching, radia PITT COUNTY tion safety, central radiopharmacy and RIA. opportunity for re search, an integrated program at State University of New York at MEMORIALHOSPITAL Buffalo School of Medicine, available July 1, 1983. Contact: M.A. & MEDICALCENTER Bender, M.D., Program Director, Nuclear Medicine Department, P.O. Box 6028 Roswell Park Memorial Institute, 666 Elm Street, Buffalo, NY 14263 Greenville, N.C. 27834 or M. Blau, Ph.D., Chairman, Nuclear Medicine Department, PeopleCare An Equal Opportunity Employer SUNY/Buffalo, 3495 Bailey Avenue, Buffalo, NY 14215. MoreHere

Volume 24, Number 1 39A VeteransAdministrationMedicalCenter LongBeach,California affiliated with A qualified Nuclear Medicine physician Universityof Californiaat Irvine is required for a 425-bed progressive modern hospital in South Western NUCLEARMEDICINERESIDENCIES Ontario. Windsor is a City of 200,000 with good educational and recreational Position available July 1984 for firstyear resi facilities. We are currently expanding dent in AMA approved program. Professional staff includes radiopharmacists and physicists our facilities to include a new gamma offeringbroad opportunities for clinicaland re camera and computer. search experience. Equal opportunity em ployer. English language proficiency required (PL 95-201). Program heads: Kenneth P. Replies to: Lyons, M.D., Nuclear Medicine Service, Dr. J. D. Bricker VAMC, and Philip Braunstein, M.D., Div., Medical Director Nuclear Medicine, UCI. Contact: Department of Diagnostic Imaging Norah Milne, M.D. The Metropolitan General Hospital Director of Training 1995 Lens Avenue Nuclear Medicine Service Windsor, Ontario N8W 1L9 VA Medical Center Long Beach, CA 90822 (213)498-6237

ST. VINCENT'S MEDICAL CENTER

SCHOOL OF NUCLEAR MEDICINE TECHNOLOGY

The St. Vincent's Medical Center School of Nuclear Medicine is accepting applications for the next class, which will begin in July 1983. REGISTEREDRADIO- LOGIC TECHNOLOGISTS or REGISTRY-ELIGIBLE Honolulu Hawaii TECHNOLOGISTS are welcome to apply to the 12- month program. Excellent didactic and clinical train Nuclear Medicine Physician ing is provided in newly constructed medical center, Unique opportunity to move into and own a plush and equipped with excellent instrumentation and perform remunerative private nuclear medicine imaging office, ing a wide range of diagnostic testing including a very radioimmunoassay lab and private referral practice. active cardiac service. Complete imaging facility servicing three hospitals and Approved forV.A. benefits. For additional informa a wide clientele of referring physicians plus a Certified tion, write or call: Independent Lab licensed for all radioimmunoassays. Matured practice with two top condition 37-tube cam Mary E. Campbell, CNMT, Educational Coordinator eras, whole body table, complete set of collimators, School of Nuclear Medicine Technology color computer and cardiac and thyroid equipment. St. Vincent's Medical Center Straight buyout of equipment, furnish 2800 Main Street, Bridgeport, Connecticut ings and practice for 50% of last year's Phone (203)576-5084 gross or will finance all or part. Available Summer 1983. Phone (808) 955-3335 or write PO Box 22536, Honolulu, HI 96822.

40A THE JOURNAL OF NUCLEAR MEDICINE POSITIONS WANTED EXPERIENCED RADIOLOGIST, NUCLEAR CARDIOLOGIST seeks to head Nuclear Medicine, NUCLEAR MEDICINE PHYSICIAN, ABNM. to develop nuclear cardiology, and lo work in Special interest in nuclear cardiology and SPECT. general radiology, CT, etc. ABR, ABNM, and SC- Seeks hospital, teaching or private practice. Reply: NR certified. Available immediately. Reply Box Box 104, Society of Nuclear Medicine, 475 Park 101, Society of Nuclear Medicine, 475 Park Ave. Ave. So., New York, NY 10016. So.. New York. NY 10016. ABNM CERTIFIED INTERNIST seeks director HOP€ ship of Nuclear Medicine section. Ten years ex perience as director of an active department of Nu FOR SALE iswhat we give. clear Medicine and diagnostic ultrasound. Exper Give to: ienced in both clinical and research aspects of Nu clear Medicine imaging, including cardiovascular PICKER MAGNASCANNER 1000: 4 years old. IECT and computer applications. RIA. and B-mode ultra Includes Teledeltose Printer: Low energy, fine focus sound. All positions will be considered. For further and high energy collimators. 2 cassettes. Excellent information and C.V., reply Box 100, Society of condition. Any offer considered. Reply: M.J. Felix, Nuclear Medicine. 475 Park Ave. So., New York, NBIMC, Dept. of Nuclear Medicine, 201 Lyons Deportment fl. Washington, D.C. 20007 NY 10016. Avenue. Newark, NJ 07112.

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UNIVERSITY OF CALIFORNIA NUCLEAR MEDICINE SAN FRANCISCO RESIDENCY PROGRAM SCHOOL OF MEDICINE 1983/1984 A Nuclear Medicine resident position is available be Resident positions (PGY-3) are available be ginning July 1, 1983 for a two-year program at San Francisco General Hospital Medical Center. ginning July 1,1983 in an AMA-approved two- The program,approvedbythe ACGMEand satisfyingthe year program. A well-rounded program is pro requirementsof the AmericanBoardof NuclearMedicine, vided with didactic instruction in physical includes didactic instruction in radiological physics and sciences and clinical applications of radio- mathematics,electronics,radiationsafety,,and nuclear medicine instrumentation. . Practical experience is provided in performance and Extensive clinical experience at VA Medi interpretation of static and dynamic imaging, computer cal Center, South Nassau Communities Hos techniques, radioimmunoassay and other in vitro tests, pital, Stony Brook plus unique training at radiopnarmacy, and therapy with radionuclides. Resi dents participate fully in the integration of these modali Brookhaven National Laboratory Research ties into patient care. Hospital. Teaching and research opportuni Prerequisite: Prior training in an ACGME-approved pro ties available. Computer assisted data ma gram in internal medicine, pathology, pediatrics, or nipulation and other special facilities. radiology. The University of California is an equal opportunity, For further information contact: affirmative action employer. Walton W. Shreeve, M.D. Ph.D Requests for further information (include CV) should be Chief, Nuclear Medicine Service (115) directed to: VA Medical Center Myron Pollycove, M.D. Northport, NY 11768 Chief, Nuclear Medicine (516)261-4400, ext. 2773/2774 San Francisco General Hospital Medical Center San Francisco, CA 94110 An Equal Opportunity Employer M/F

Volume 24, Number 1 41A Purity Interfering, longer lived contaminants with the presence of higher energy , namely 1124 (4.15d. 603 keV), 1126 (13.02d. 389 keV, 666 keV), Na 24 (15.03hr, 1369 keV, 2754 keV). Dosimetry With comparable administered activity, longer lived, radionucjidic contaminants deliver twice the radiation dose to the thyroid. Useful Life Expiration time is 24 hours after time of calibration. Image Quality ^ "

The effect over requires administration of the time of higher • agent as soon as reasonably relative pro ^ possible after receipt portions of to minimize their radionuclidic effect on image contaminants quality.

Compare the radionuclidic purity, our new Sodium Iodide 1123 is radiation dose, useful life and contrasted here with their agent image quality of our new Sodium in the Rollo phantom studies, a Iodide 1123 with their Sodium reflection of clinical situations Iodide 1123. in which various sized, cold *—allesions are Ours has a small an of low energy lodin ated within so image quality is not a radioactive tissue. compromised, usef"1 Compare and you'll life is extended and know new Sodium patient receives a Ic > Iodide! 123 from i Benedict Nuclear is The lack of high en<~ the purest, safest radiopharmaceutical radiocontaminants to evaluate thyroid ction and 1ology. Hiñes.H.H.. Lagunas-Solar. M: Comparison of Scintillation Camera Images for I 123 Produced by (p. 2n) and (p. 5n) Reactions. J NucíMed 23:P121. 1982 (Sci Exhibit). Time of Calibration 24 Hours Post TOC Low Energy Pinhole Collimator (Picker) (p, 2n) Commercial 1123

Brief Summary—forcomplete prescribing Indications and Use: Administration of Sodium Iodide administered to a pregnant woman or can affect information consult package insert. I 123 is indicated as a diagnostic procedure to be used reproduction capacity. Sodium Iodide 1123 should be in evaluating thyroid function and/or morphology. given to a pregnant woman only if clearly needed. Sodium Iodide 1123 Contraindications: To date there are no known It is not known whether this drug is excreted in human Diagnostic—Capsules for Oral Administration contraindications to the use of Sodium Iodide 1123 milk. Because many drugs are excreted in human milk, Description: BNPI Sodium Iodide 1123 (Na '23I ) capsules. caution should be exercised when Sodium Iodide 1123 is administered to a nursing woman. for diagnostic use is supplied in capsules for oral Warnings: Females of childbearing age and children administration. The capsules are available in a strength under 18 should not be studied unless the benefits Safety and effectiveness in children have not of 200 microcuries (uCi) Iodine 123 at time of calibration. anticipated from the performance of the test outweigh been established. The I 123 utilized in the preparation of BNPI's Sodium the possible risk of exposure to the amount of associated with the test. Adverse Reactions: Although rare, reactions Iodide 1123 capsules contains 1.9% or less 1125 associated with the administration of Sodium Iodide as the only detectable radionuclidic impurity at time Precautions: Pregnancy Category C. Animal reproduction studies have not been conducted with isotopes for diagnostic use include, in decreasing order of calibration. At time of expiry, the capsules contain not of frequency, nausea, vomiting, chest pain, tachycardia, less than 91.2% 1123, not more than 8.4% 1125 and Sodium Iodide 1123. It is also not known whether itching skin, rash and hives. not more than 0.4% all other radionuclides. Sodium Iodide 1123 can cause fetal harm when Purity No interfering radionuclidic contaminants. Dosimetry With comparable administered activity, less than one-half the radiation dose to the thyroid. ife Expiration time is 30 hours after time of calibration. mage Quality Images retain high quality throughout the useful life of the agent.

of our scientists, researchers, tech nicians and management are known and respected throughout the field of nuclear Sodium Iodide 1123 is the first radio- medicine. pharmaceutical to be commercially distributed by As advocates of quality Benedict Nuclear studies, we share your Pharmaceuticals, In concerns and welcome And our first isthe fir fc^ your inquiries. We invite you to get to know We are a company v Benedict Nuclear so you a sole purpose—to can experiencethe finest develop and make right from the start. available the highes quality radiopharrm ceuticals in the worl And though our nan may be new, the nar benedict nuclear Pharmaceuticals inc. P.O. Box 548 Time of Calibration 24 Hours Post TOC Golden, CO 80401 Low Energy Pinhole Collimator (Picker) (p. 5n)BNPII123

Dosage and Administration: The recommended radionuclides and whose experience and training have Absorbed Dose (rads 100 uCi TOC) oral dose for the average patient (70 kg) is 100-400 uCi. been approved by the appropriate government agency Maximum The lower part of the dosage range (100 uCi) is authorized to license the use of radionuclides. recommended for uptake studies alone, and the higher 123Target Thyroid Sodium Iodide I part (400 uCi) for thyroid imaging. The individual patient Iodide How Supplied: BNPI Sodium Iodide 1123 is supplied dose should be measured by a suitable radioactivity OrganThyroidUptake(%)515 (P.5n)0.5 (p.2n)1.23.6 113126.0 as capsules for oral administration in a strength of calibration system (dose calibrator) immediately prior 200 uCi at time of calibration. to each administration. The determination of 1123 1.6 80.0 concentration in the thyroid gland may be initiated at 25BNPI 2.9Commercial6.0Sodium 130.0 six hours after administering the dose and should be '•Reference: MIRO Dose Estimate Report No. 5 measured in accordance with standardized procedures. 'Summary of Current Radiation Dose Estimates to Humans From '"I. '"I. m\. '»1,130I.'"I, and '"I Radiation Dosimetry: A comparison of the estimated Sodium Iodide.' J NucíMed 16:857-60. 1975. absorbed radiation dose to the thyroid of an average patient (70 kg) from an oral dose of 100 uCi of BNPI Sodium Iodide 1123 (p. 5n). Commercial (p. 2n) Sodium Special Consideration: Radiopharmaceuticals should Iodide 1123 or Sodium Iodide 1131 at Time of Calibration be used only by individuals who are qualified by training (TOC) is shown below: ' and experience in the safe use and handling of NUCLEAR MEDICINE i !.>ls.,,Kl R-idulu-nff. REVIEW

, ^. 1,111 SYLLABUS . \ Ini.'Uy\ Pili-li.. ,

Rad ~.i'. Peter T. Kirchner, M.D., Editor

PETER T. KIRCHNER, M.D., EDITOR ÃŒHHÃŒMMHHM softcover; 6 x 9; 630 pp.

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ORDER NOW! $30.00 plus $2.50 postage and handling for each book ordered. Pre-payment is required in US funds drawn on US banks only. Add $1.50 processing fee for US dollars drawn on Canadian banks; $20.00 on banks outside US and Canada. Make checks payable to: The Society of Nuclear Medicine. Order from: Book Order Department, Society of Nuclear Medicine, 475 Park Ave. So., NY, NY 10016. Prices are subject to change without notice.

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46A THE JOURNAL OF NUCLEAR MEDICINE HEPATOLITE Technetium Te99m Disofenin Kit INDICATIONSANDUSAGE:TechnetiumTc99mDisoleninisindicatedasahepatobiliary The Society of imagingagent CONTRAINDICATIONS:Noneknown Nuclear Medicine WARNINGS:Thetheoreticalpossibilityotallergicreactionsshouldbeconsideredin patientswhoreceivemultipledoses Announces PRECAUTIONS:Contentsofthevialareintendedonlyloruseinthepreparationol TechnetiumTc99mDisoleninandareNOTtobeadministereddirectlylo(hepatient TechnetiumTc99mDisoleninaswellasotherradioactivedrugsmustbehandledwithcare ANEW andappropriatesafetymeasuresshouldbeusedtominimizeradiationexposuretoclinical personnelAlsocareshouldbetakentominimizeradiationexposuretothepatientsconsis PUBLICATION tentwithproperpatientmanagement TechnetiumTc99mDisofeninshouldbeformulatedwithinsix(6)hourspriortoclinicaluse. This volume, sponsored by the Computer Carcinogenesis.Mutagenesis.ImpairmentofFertility and Instrumentation Councils, contains 25 Nolongtermanimalstudieshavebeenperformedtoevaluatecarcinogenicpotentialor papers and is divided into five sections covering whetherTechnetiumTc99mDisoleninaffectsfertilityinmalesorfemales important areas of computer software develop PregnancyCategoryC AnimalreproductivestudieshavenotbeenconductedwithTechnetiumTc99mOisofeninItis ment in nuclear medicine, such as functional alsonotknownwhetherTechnetiumTc99mDisolenincancausefetalharmwhenadmin mapping and imaging of organ systems and the isteredtoapregnantwomanorcanatlectreproductioncapacityTechneliumTc99mshould cardiac system. begiventoapregnantwomanonlyifclearlyneeded Ideally,examinationsusingradiopharmaceuticals.especiallythoseelectiveinnature,ola Other important aspects of computer womanofchildbearingcapabilityshouldbeperformedduringthe(irsilew(approximately10) development and use—background subtraction, daysfollowingtheonsetofmenses computed tomography, and image display NursingMothers techniques—are also included, making this TechnetiumTc99misexcretedinhumanmilkduringlactationTherefore,formulafeedings shouldbesubstitutedforbreastfeeding attractive and comprehensive book indispen PediatrieUse sable to a wide audience of physicians, medical Safelyandeffectivenessinchildrenbelowtheageof18havenotbeenestablished research scientists, and computer specialists. Radiopharmaceuticalsshouldbeusedonlybyphysicianswhoarequalifiedbytrainingand experienceinthesaleuseandhandlingofradionuclidesandwhoseexperienceandtraining havebeenapprovedbytheappropriategovernmentagencyauthorizedtolicensetheuseol radionuclides ADVERSEREACTIONS:Noadversereactionsspecificallyattributabletotheuseof FunctionalMapping TechnetiumTc99mDisofeninhavebeenreported DOSAGEANDADMINISTRATION:ThesuggesteddoserangelorIV administration,after reconstitutionwithoxidant-freesodiumpertechnetateTc99minjection,tobeemployedinthe ofOrganSystems averagepatient(70kg)is Non-Jaundicedpatient 1-5mCi and other computer topics PatientswithserumbilirubinlevelgreaterthanSrng/dl: 3-8mCi Thepatientdoseshouldbemeasuredbyasuitableradioactivitycalibrationsystemimme diatelypriortopatientadministration(IIbloodisdrawnintothesyringe,anyunnecessary delaypriortoinjectionmayleadtoclotformationinsitu) Donotbackflushthesyringe, slowinjectionisrecommendedRadiochemicalpurityshouldbecheckedprior(opatient administration Thepatientshouldbeinafastingstate;4hoursispreferableFalsepositives(non-visual ization)mayresultil thegallbladderhasbeenemptiedbyingestionotfood Parenleraldrugproductsshouldbeinspectedvisuallylorpaniculatematteranddiscoloration priortoadministrationwheneversolutionandcontainerpermit HOWSUPPLIED:NEN'sHEPATOLITE'".TechnetiumTc99mOisoleninKitissuppliedin kitsoffive(5)andthirty(30)vials,sterileandpyrogen-free.eachvialcontaininginlyoph- ilizedlorm: Disofenin 20mg SlannousChloride(SnCI;•2H20)(Minimum) 0.24mg TotalTin,Maximum(asstannouschloride.SnCI,•2H,0) 06mg ThepHisadjustedtobetween55-65withhydrochloricacidand/orsodiumhydroxide solutionpriortolyophilizationThecontentsolthevialwerelyophilizedundernitrogenStore atroomtemperature(15°-30°C)beforeandafterreconstitutionProtecttramlightThelyoph ilizeddrugproductislightsensitiveTechnetiumTc99mDisolenincontainsnopreserva tivesIncludedineachlive(5)vialkitisone(1)packageinsertandsix(6)radiationlabels Includedineachthirty(30)vialkitisone(1)packageinsertandthirty-six(36)radiationlabels ThecomponentsofIheTechnetiumTc99mDisofeninKitaresuppliedsterileandnon- pyrogenicAsepticproceduresnormallyemployedinmakingadditionsandwithdrawalsfrom sterile,non-pyrogeniccontainersshouldbeusedduringadditionofpertechnetatesolution andthewithdrawaloldosestorpatientadministration TechneliumTc99mDisoleninispreparedbyaddingnomorethan100millicuriesoladditive- Ireesterile,non-pyrogenicsodiumpertechnetateTc99msolutionin2-3ml(sZOmCi/ml)to thevialandswirlingloraboutoneminuteShieldingshouldbeutilizedwhenpreparingIne Edited by Peter D. Esser, Ph.D. TechnetiumTc99mDisolenin CatalogNumberNRP-475(5vialkit) CatalogNumberNRP-475C(30vialkit) November1982

New England Nuclear

601 Treble Cove Rd . North Billerica. MA 01862 ORDER FUNCTIONAL MAPPING NOW! Call Toll-Free. 800-225-1572/Telex 94-0996 (In Mass and International 617-482-9595) $19.00 for SNM members; $28.00 for non-members; plus $2.50 postage and handling for each book ordered. Prepayment required. Canada: NEN Canada. 2453 46th Avenue. Lachme. Que H8T 3C9 Tel 514-636-4971 Order from: Book Order Department, Society of Nuclear Medicine, Europe: NEN Chemicals GmbH. D-6072 Dreieich. W Germany. Rostlach 401240 475 Park Avenue South. New York. New York 10016 Tel (06103)803-0 Order Entry (06103)803115

Volume 24, Number 1 47A HEPATOLITE TechnetíumTe99m Disofenin Kit

"DISIDA [Hepatolite] has been extremely effective in distinguishing medical from surgicaljaundice.. .with Effective even at the bilirubin ranging from 1.1to 24.5 mg%." high bilirubin levels Weissmann et al'

"Visually and computationally, DISIDA fHepatoliteJ was superior fto other IDA agents] in terms of relative uptake Superior liver uptake in the liver and liver washout." and washout Hernandez and Rosenthall2

'During the first hour after injection (the critical time for Highest target to- imaging), diisopropyl-IDA [Hepatolite] had the highest rate of biliary excretion (76.2%), which should result in the best visualization of the biliary system..." background ratio Wistow et al3

"We were able to clearly identify the intrahepatic ducts in Better intrahepatic 46 of the 54 patients imaged with PRIDA [Hepatolite] whereas we were not able to identify them clearly in any of the 21 patients imaged with BIDA." duct visualization Readet al4

Tc-99m DISIDA [Hepatolite] appears to incorporate the best properties of all the currently available IDA analogs.. The only agent it isthe only IDA derivative that a "hot lab" would need to stock." you need to stock Weissmannet al5

References 1. Weissmann HS, Badia JD. Hall I abstracted: J NucíMed 21:18. I960. 2. Hernandez M, Rosenthall L: Clin NucíMed 5:159. 1980. 3. Wistow BW, Subramanian G, Gagne GM, et al: Radiology 128:793, 1978. 4. Read ME, Teaies CD, Croft BY et al: In press. 5. Weissmann HS, Sugarman LA, Freeman LM, in Freeman LM, Weissmann HS (eds): Nuclear Medicine Annual 1981.New York, Raven Press,1981,pp 35-89. 6. Weissmann HS, Rosenblatt R,Sugarman LA, et al: Seminars in Ultrasound 1:134,1980.

Seepreceding page for brief prescribing information. Thé"best universal agent' for hepatobiliary imaging

Blllrubln: 24.5 mg/dl. ThisnormalHepatolitestudydemonstratesbiliarytractpatency—suggestingthat the patient'shyper- bilirubinemia is due to parenchyma!disease.Note the shielding of intestinal activity on the 90-minute study. (Reproducedwith permission from reference6.)

3 min 30 min 120 min 240 min

Blllrubln: 23.0 mg/dl. In thispatientwho presentedwith painlessjaundice,cholescintigraphywith '""Tc-HlDAwasnondiagnostic. Note the absenceof significant liver uptake throughout the study—onlypersistentrenal excretionand blood background. CT revealeda massin the head of the pancreas.(Reproducedwith permissionfrom reference6.) HEPATOLITE TechnetiumTc99m DisofeninKit

New England Nuclear a Du Pont company RESEARCH GRADE RADIOCHEMICALS

FOR LABELING: Monoclonal Antibodies Chelates Antibodies Blood Cells Proteins

FOR LABELING IN These products are available for purchase by investi gators for use in laboratory animal testing, in vitro test IN-VITRO RESEARCH: ing, Radioactive Drug Research Committee 21 CFR HIGH SPECIFIC ACTIVITY SODIUM 361.1, and IND holders. In addition, these products are available for purchase by manufacturers of in vitro and IODIDE 1-125 in vivo products. Sodium Iodide 1-123 and Indium Chlo Medium pH, medium concentration ride ln-111 are autoclaved at 121 C for 33 minutes to Medium pH, high concentration insure stability during storage. However, these prod Low pH, medium concentration ucts are not certified to be sterile or non-pyrogenic and Low pH, high concentration no such guarantee is implied. TIN 113 INDIUM 113m GENERATORS CAUTION: THESE PRODUCTS ARE NOT FOR 5mCi-100mCi HUMAN USE IN PRESENT FORM AND ARE NOT TESTED FOR STERILITY OR FOR LABELING IN IMAGING APYROGENICITY. RESEARCH: For technical information or product literature, please SODIUM IODIDE 1-123 call toll free 800-227-0492 (in California 800-772-2477, INDIUM CHLORIDE In-Ill internationally (415) 652-7650), or TELEX 335-491 (answer back MEDI-PHYS EMVIL). Or, you may write HIGH SPECIFIC ACTIVITY SODIUM to Marketing Manager, Radiochemicals, at the address IODIDE 1-131 below. medi+i Medi-Physics Inc., 5801 Christie Avenue, Emeryville, California 94608 All reactor products are jointly produced by UNION CARBIDE CORPORATION and CINTICHEM, INC., a wholly-owned subsidiary of MEDI-PHYSICS, INC.