Development and Characterization of Velocity Workspaces for the Human Knee

Louisiana State University LSU Digital Commons LSU Historical Dissertations and Theses Graduate School 2001 Development and Characterization of Velocity Workspaces for the Human Knee. John Eric Fuller Louisiana State University and Agricultural & Mechanical College Follow this and additional works at: https://digitalcommons.lsu.edu/gradschool_disstheses Recommended Citation Fuller, John Eric, "Development and Characterization of Velocity Workspaces for the Human Knee." (2001). LSU Historical Dissertations and Theses. 403. https://digitalcommons.lsu.edu/gradschool_disstheses/403 This Dissertation is brought to you for free and open access by the Graduate School at LSU Digital Commons. It has been accepted for inclusion in LSU Historical Dissertations and Theses by an authorized administrator of LSU Digital Commons. For more information, please contact [email protected]. INFORMATION TO USERS This manuscript has been reproduced from the microfilm master. UMI films the text directly from the original or copy submitted. Thus, some thesis and dissertation copies are in typewriter face, while others may be from any type of computer printer. The quality of this reproduction is dependent upon the quality of the copy submitted. Broken or indistinct print, colored or poor quality illustrations and photographs, print bleedthrough, substandard margins, and improper alignment can adversely affect reproduction. In the unlikely event that the author did not send UMI a complete manuscript and there are missing pages, these will be noted. Also, if unauthorized copyright material had to be removed, a note will indicate the deletion. Oversize materials (e.g., maps, drawings, charts) are reproduced by sectioning the original, beginning at the upper left-hand comer and continuing from left to right in equal sections with small overlaps. Photographs included in the original manuscript have been reproduced xerographically in this copy. Higher quality 6" x 9" black and white photographic prints are available for any photographs or illustrations appearing in this copy for an additional charge. Contact UMI directly to order. ProQuest Information and Learning 300 North Zeeb Road. Ann Arbor, Ml 48106-1346 USA 800-521-0600 Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. DEVELOPMENT AND CHARACTERIZATION OF VELOCITY WORKSPACES FOR THE HUMAN KNEE A Dissertation Submitted to the Graduate Faculty of the Louisiana State University and Agricultural and Mechanical College in partial fulfillment of the requirements for the degree of Doctor of Philosophy in The Department of Mechanical Engineering by John Eric Fuller B.S., Louisiana State University, 199S December, 2001 Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. UMI Number 3042619 UMI* UMI Microform 3042619 Copyright 2002 by ProQuest Information and Learning Company. All rights reserved. This microform edition is protected against unauthorized copying under Title 17, United States Code. ProQuest Information and Learning Company 300 North Zeeb Road P.O. Box 1346 Ann Arbor, Ml 48106-1346 Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. For my Father, my Mother and my Sister— my foundation, my sanctuary, my motivation, my inspiration. ii Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. ACKNOWLEDGEMENTS This dissertation represents what I have been doing with my life for the past six years but these were things that I could not have done alone. As I consider those who have stepped up to lend me support, assistance, and guidance, it suddenly occurs to me that the current resurgence of patriotism, generosity, and humanity is not something that has been absent during my research. In fact, it has blessed me my entire life. With that the first people I must thank are those who gave me life. My parents brought me into this world, protected me from it, gave me the tools to survive in it, and the inspiration and courage that have kept me going. Thanking them almost seems absurd, for how do you communicate infinite gratitude with mere words? My sister kept me honest, suffered my moodiness, been an incredible role model, and taught me more than she will ever know and for that I will never be able to thank her enough. She has set the bar high and I hope one day I might be able to see just how high she has leapt. To Dr. Michael C. Murphy, my appreciation for the unwavering example, the opportunity, and for being more than a teacher and mentor. Thank you for being a friend and listening to what I had to say, no matter how ridiculous. Dr. Warren N. Waggenspack, Jr., also more than a teacher and mentor, you trusted me with your home and while it might just seem fair enough to you, that kind of trust is not something I regard lightly. For the remainder of my committee, Dr. Madden, Dr. Kerwin, and Dr. Welsch, thank you for the guidance, the patience, and the time you have given to this work. iii Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Rob, Donovan, Jake, Garrett, and Danny...for being true friends, and the subjects of way too many stories that I am sure will be further embellished with time, my eternal gratitude and, understandably, my continued silence. My gratitude must also be extended to those who have made specific technical contributions to the research. These include: Chris Schwehm for his assistance in accessing data, Timothy Morgan for the use of his thresholding code, and Anna Omeltchenko and Mingli Zhang for their preliminary development of the concepts of displacement workspaces. Specific acknowledgements for data collection include: ( 1) Massachusetts Institute of Technology Data Collection and Manipulation-Dr. Murali Jasty of Massachusetts General Hospital for arranging CT scans, Jane Pardy of Massachusetts General Hospital for operating the CT scanner, Professor Derek Rowell from the Massachusetts Institute of Technology for initial aid with CT scan imaging, Michael Stracher of the Orthopaedics Research Laboratory at Massachusetts General Hospital for data conversion, Mingli Zhang from Louisiana State University for data conversion, Timothy Morgan from Louisiana State University for preliminary coding (2) University o f Minnesota Data Collection and Manipulation-Dr. Greg Brown of the University of Minnesota and Regions Hospital for specimen acquisition, specimen dissection, marker placement, setting up the CT scans, general clinical guidance, and putting up with me for four days, Paul Grunhovd, R.T. of Regions Hospital for operating the CT scanner, Fred Wentorf from the Biomechanics Department of the University of Minnesota for specimen storage and handling, Synthes Corporation (Paoli, PA) for the donation of titanium screws (3) Those with the Visible Human Project (4) Health South iv Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Diagnostic Center Data Collection and Manipulation-Dr. Charles Greeson of Heath South Diagnostic Center for setting up the MRI scans and general clinical guidance David Frye of Heath South Diagnostic Center for operating the MRI scanner Chris Schwehm from the Remote Sensing and Image Processing Lab at Louisiana State University for data conversion. I also need to extend thanks to the people of the College of Engineering Dean’s Office, including: Vicki Hannan, Mickey Adler, Lisa Hebert, Shea Dunigan, Cathy Hill, Lisa Bergens, Lisa Launey, Cathy Harrison, Dr. Julius Langlinais, and the office student workers over the years. Their suggestions, help, employment, and indulgences for my benefit have helped enormously over the years. Last but certainly no least, I would be derelict in my gratuities if I did not acknowledge my fellow students who put up with my shenanigans, kept me on my toes, and kept our lab an entertaining place to work. To all of you, my sincere gratitude: Yohannes Desta, Tim Morgan, Jim O’Bryan, Anna Omeltchenko, Jim Rodgers, Christophe Marques, Fred Majkut, Kevin Zanca, Gary Templet, Mircea Despa, Dawit Yemane, Proyag Datta, Summer Johnson, Abhinav Bhushan, Tracy Morris, Catherine Oropeza, Dinakar Palaparti, John Williams, Madhulika Sathe, Michael Mitchell, Dwhyte Barrett, Lyle Breaux, Chris Cowart, and John Breeden. v Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. TABLE OF CONTENTS DEDICATION_______________________________________________________ u ACKNOWLEDGEMENTS____________________________________________ iil LIST OF TABLES___________________________________________________ ix LIST OF FIGURES___________________________________________________ x LIST OF SELECTED SYMBOLS AND ACRONYMS____________________ xiii ABSTRACT________________________________________________________ xv CHAPTER 1. INTRODUCTION________________________________________ 1 1.1 Motivation.............................................................................................................1 1.1.1 Clinical Significance ...................................................................................... 2 1.1.2 Workspaces in Medicine ............................................................................... 7 1.1.3 Scientific Interest ..........................................................................................

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