University of Massachusetts Medical School eScholarship@UMMS GSBS Dissertations and Theses Graduate School of Biomedical Sciences 1997-07-02 In Vivo Functional Analysis of the Saccharomyces Cerevisiae SWI/SNF Complex: A Dissertation Loree Griffin Burns University of Massachusetts Medical School Let us know how access to this document benefits ou.y Follow this and additional works at: https://escholarship.umassmed.edu/gsbs_diss Part of the Amino Acids, Peptides, and Proteins Commons, Cells Commons, Fungi Commons, and the Genetic Phenomena Commons Repository Citation Burns LG. (1997). In Vivo Functional Analysis of the Saccharomyces Cerevisiae SWI/SNF Complex: A Dissertation. GSBS Dissertations and Theses. https://doi.org/10.13028/2g6f-k063. Retrieved from https://escholarship.umassmed.edu/gsbs_diss/202 This material is brought to you by eScholarship@UMMS. It has been accepted for inclusion in GSBS Dissertations and Theses by an authorized administrator of eScholarship@UMMS. For more information, please contact
[email protected]. In vivo functional analysis of the Saccharomyces cerevisiae SWI/SNF complex A Dissertation Presented Loree Gri Burns Submitted to the Faculty of the University of Massachusetts Graduate School of Biomedical Sciences, Worcester in partial fulfment of the requirements for the degree of: Doctor of Philosophy July 1997 Biochemistry Approved as to style and content by: Martha J. Fedor, Ph.D., Chair of Committee Kendall L. Knight, Ph.D., Member of Committee Seth R. Stern, Ph.D., Member of Committee Richard E. Baker, Ph.D., Member of Committee Steven Buratowski, Ph.D., Member of Committee Craig L. Peterson, Ph.D., Dissertation Mentor III DEDICATION for Gerry, with love and gratit"U ABSTRACT Chromatin remodelig is crucial to transcriptional regulation in vivo and a number of protein complexes capable of alterig genomic architecture in the budding yeast Saccaromyces cerevisia have been identifed.