Aerospace Medicine & Biology Space Medicine & Biology Aero 9

Home , Carbohydrate chemistry, Microtechnique

Aerospace Medicine NASA SP-7011 (232) and Biology May 1982 IWNSA A Continuing Bibliography with Indexes

(NASA-SP-701 1 (232) ) AT. CE MEDICINE AND N82-2898U BIOLOGY: A CONTINUING BIBLIOGRAPHY WITH INDEXES (SUPPLEMENT 232) (National Aeronautics and Space Administration) 137 p Unclas Hc <7.QQ CSCL Ofa£ 00/52 25483

National Aeronautics and Space Administration

Aerospace Medicine & Biology space Medicine & Biology Aero 9 Medicine & Biology Aerospao dicine & Biology Aerospace M ne & Biology AerosjatoiMedici Biology Aerospace Medicine & gy Aerospace Medicine & Biolo 3rospace Medicine & Biology / pace Medicine & Biology Aeros Medicine & Biology Aerospace cine & Biology Aerospace Med & Biology Aerospace Medicine < ACCESSION NUMBER RANGES

Accession numbers cited in this Supplement fall within the following ranges.

STAR (N-10000 Series) N82-16040 - N82-18118

IAA (A-10000 Series) A82-18840 - A82-22250

This bibliography was prepared by the NASA Scientific and Technical Information Facility operated for the National Aeronautics and Space Administration by PRC Government Information Systems. NASA SP-7011(232)

AEROSPACE MEDICINE AND BIOLOGY

A CONTINUING BIBLIOGRAPHY WITH INDEXES

(Supplement 232)

A selection of annotated references to unclassified reports and journal articles that were introduced into the NASA scientific and technical information system and announced in April 1982 in

Scientific and Technical Aerospace Reports (STAR) International Aerospace Abstracts (IA A).

Scientific and Technical Information Branch 1982 National Aeronautics and Space Administration Washington, DC NASA SP-7011 and its supplements are available from the National Technical Information Service (NTIS). Questions on the availability of the predecessor publications, Aerospace Medicine and Biology (Volumes I - XI) should be directed to NTIS.

This supplement is available as NTISUB/123/093 from the National Technical Information Service (NTIS), Springfield, Virginia 22161 at the price of $7.00 domestic; $14.00 foreign. INTRODUCTION

This Supplement to Aerospace Medicine and Biology lists 437 reports, articles and other documents announced during April 1982 in Scientific and Technical Aerospace Reports (STAR) or in International Aerospace Abstracts (IAA). The first issue of the bibliography was published in July 1964. In its subject coverage, Aerospace Medicine and Biology concentrates on the biological, physiological, psychological, and environmental effects to which man is subjected during and following simulated or actual flight in the Earth's atmosphere or in interplanetary space. References describing similar effects of biological organisms of lower order are also included. Such related topics as sanitary problems, pharmacology, toxicology, safety and survival, life support systems, exobiology, and personnel factors receive appropriate attention. In general, emphasis is placed on applied research, but references to fundamental studies and theoretical principles related to experimental development also qualify for inclusion. Each entry in the bibliography consists of a bibliographic citation accompanied in most cases by an abstract. The listing of the entries is arranged in two major sections.: IAA Entries and STAR Entries, in that order. The citations, and abstracts when available, are reproduced exactly as they appeared originally in IAA or STAR, including the original accession numbers from the respective announcement journals. This procedure, which saves time and money, accounts for the slight variation in citation appearances. Two indexes -- subject and personal author -- are included. An annual index will be prepared at the end of the calendar year covering all documents listed in the 1982 Supplements. AVAILABILITY OF CITED PUBLICATIONS

IAA ENTRIES (A82-10000 Series) All publications abstracted in this Section are available from the Technical Information Service, American Institute of Aeronautics and Astronautics, Inc. (AIAA), as follows: Paper copies of accessions are available at $8.00 per document. Microfiche*1) of documents announced in IAA are available at the rate of $4.00 per microfiche on demand, and at the rate of $1.35 per microfiche for standing orders for all IAA microfiche.

Minimum air-mail postage to foreign countries is $2.50 and all foreign orders are shipped on payment of pro-forma invoices.

All inquiries and requests should be addressed to AIAA Technical Information Service. Please refer to the accession number when requesting publications.

STAR ENTRIES (N82-10000 Series) One or more sources from which a document announced in STAR is available to the public is ordinarily given on the last line of the citation. The most commonly indicated sources and their acronyms or abbreviations are listed below. If the publication is available from a source other than those listed, the publisher and his address will be displayed on the availability line or in combination with the corporate source line.

Avail: NTIS. Sold by the National Technical Information Service. Prices for hard copy (HC) and microfiche (MF) are indicated by a price code preceded by the letters HC or' MF in the STAR citation. Current values for the price codes are given in the tables on page vii. Documents on microfiche are designated by a pound sign (#) following the accession number. The pound sign is used without regard to the source or quality of the microfiche. Initially distributed microfiche under the NTIS SRIM (Selected Research in Microfiche) is available at greatly reduced unit prices. For this service and for information concerning subscription to NASA printed reports, consult the NTIS Subscription Section, Springfield, Va. 22161. NOTE ON ORDERING DOCUMENTS: When ordering NASA ^publications (those followed by the * symbol), use the N accession number. NASA patent applications (only the specifications are offered) should be ordered by the US-Patent-Appl-SN number. Non-NASA publications (no asterisk) should be ordered by the AD, PB, or other report number shown on the last line of the citation, not by the N accession number. It is also advisable to cite the title and other bibliographic identification.

Avail: SOD (or GPO). Sold by the Superintendent of Documents, U.S. Government Printing Office, in hard copy. The current price and order number are given following the availability line. (NTIS will fill microfiche requests, at the standard $4.00 price, for those documents identified by a # symbol.)

Avail: NASA Public Document Rooms. Documents so indicated may be examined at or purchased from the National Aeronautics and Space Administration, Public Document Room (Room 126), 600 Independence Ave., S.W., Washington, D.C. 20546, or public document rooms located at each of the NASA research centers, the NASA Space Technology Laboratories, and the NASA Pasadena Office at the Jet Propulsion Laboratory.

(1) A microfiche is a transparent sheet of film. 105 by 148 mm in size containing as many as 60 to 98 pages of information reduced to micro images (not to exceed 26.1 reduction). Avail: DOE Depository Libraries. Organizations in U.S. cities and abroad that maintain collections of Department of Energy reports, usually in microfiche form, are listed in Energy Research Abstracts. Services available from the DOE and its depositories are described in a booklet, DOE Technical Information Center - Its Functions and Services (TID-4660), which may be obtained without charge from the DOE Technical Information Center.

Avail: Univ. Microfilms. Documents so indicated are dissertations selected from Dissertation Abstracts and are sold by University Microfilms as xerographic copy (HC) and microfilm. All requests should cite the author and the Order Number as they appear in the citation.

Avail: USGS. Originals of many reports from the U.S. Geological Survey, which may contain color illustrations, or otherwise may not have the quality of illustrations preserved in the microfiche or facsimile reproduction, may be examined by the public at the libraries of the USGS field offices whose addresses are listed in this introduction. The libraries may be queried concerning the availability of specific documents and the possible utilization of local copying services, such as color reproduction.

Avail: HMSO. Publications of Her Majesty's Stationery Office are sold in the U.S. by Pendragon House, Inc. (PHI), Redwood City, California. The U.S. price (including a service and mailing charge) is given, or a conversion table may be obtained from PHI.

Avail: BLL (formerly NLL): British Library Lending Division, Boston Spa, Wetherby, Yorkshire, England. Photocopies available* from this organization at the price shown. (If none is given, inquiry should be addressed to the BLL.)

Avail: Fachinformationszentrum, Karlsruhe. Sold by the Fachinformationszentrum Energie, Physik, MathematikGMBH, Eggenstein Leopoldshafen, Federal Republic of Germany, at the price shown in deutschmarks (DM).

Avail: Issuing Activity, or Corporate Author, or no indication of availability. Inquiries as to the availability of these documents should be addressed to the organization shown in the citation as the corporate author of the document.

Avail: U.S. Patent and Trademark Office. Sold by Commissioner of Patents and Trademarks, U.S. Patent and Trademark Office, at the standard price of 50 cents each, postage free.

Other availabilities: If the publication is available from a source other than the above, the publisher and his address will be displayed entirely on the availability line or in combination with the corporate author line. ADDRESSES OF ORGANIZATIONS

American Institute of Aeronautics and National Technical Information Service Astronautics 5285 Port Royal Road Technical Information Service Springfield, Virginia 22161 555 West 57th Street, 12th Floor New York, New York 10019

Pendragon House, Inc. British Library Lending Division, 899 Broadway Avenue Boston Spa, Wetherby, Yorkshire, Redwood City, California 94063 England

Commissioner of Patents and Superintendent of Documents Trademarks U.S. Government Printing Office U.S. Patent and Trademark Office Washington, D.C. 20402 Washington, D.C. 20231

University Microfilms Department of Energy A Xerox Company Technical Information Center 300 North Zeeb Road P.O. Box 62 Ann Arbor, Michigan 48106 Oak Ridge, Tennessee 37830

ESA-lnformation Retrieval Service University Microfilms, Ltd. ESRIN Tylers Green Via Galileo Galilei London, England 00044 Frascati (Rome) Italy

Fachinformationszentrum Energie, Physik, U.S. Geological Survey Mathematik GMBH 1033 General Services Administration 7514 Eggenstein Leopoldshafen Building Federal Republic of Germany Washington, D.C. 20242

Her Majesty's Stationery Office P.O. Box 569, S.E. 1 U.S. Geological Survey London, England 601 E. Cedar Avenue Flagstaff, Arizona 86002

NASA Scientific and Technical Information Facility P.O. Box 8757 U.S. Geological Survey B.W.I. Airport, Maryland 21240 345 Middlefield Road Menlo Park, California 94025

National Aeronautics and Space Administration Scientific and Technical Information U.S. Geological Survey Branch (NST-41) Bldg. 25, Denver Federal Center Washington, D.C. 20546 Denver, Colorado 80225 NTIS PRICE SCHEDULES

Schedule A STANDARD PAPER COPY PRICE SCHEDULE

(Effective January 1, 1982)

Price Page Range North American Foreign Code Price Price A01 Microfiche $ 4.00 S 8.00 A02 001-025 6.00 12.00 A03 026-050 7.50 15.00 A04 051-075 9.00 18.00 A05 076-100 10.50 21.00 A06 101-125 12.00 24.00

A07 126-150 13.50 27.00 A08 151-175 15.00 30.00 A09 176-200 16.50 33.00 A10 201-225 18.00 36.00 A11 226-250 19.50 39.00

A12 251-275 21.00 4200 A13 276-300 22.50 45.00 A14 301-325 2400 48.00 A15 326-350 25.50 51.00 A16 351-375 27.00 54.00

A17 376-400 28.50 57.00 A18 401-425 30.00 6000 A19 426-450 31.50 6300 A20 451-475 33.00 66.00 A21 476-500 34.50 69.00

A22 501-525 36.00 72.00 A23 526-550 37.50 75.00 A24 551-575 39.00 78.00 A25 576-600 40.50 81.00 601-up -21

A99-Write for quote

1 / Add $1.50 for each additional 25 page increment or portion thereof for 601 pages up.

21 Add $3.00 for each additional 25 page increment or portion thereof for 601 pages and more.

Schedule E EXCEPTION PRICE SCHEDULE Paper Copy & Microfiche

Price North American Foreign Code Price Price E01 S 6.50 $ 13.50 E02 7.50 15.50 £03 9.50 19.50 E04 11.50 23.50 £05 13.50 27.50

E06 15.50 31.50 E07 17.50 35.50 £08 19.50 39.50 £09 21.50 43.50 £10 23 50 47.50

£11 25.50 51.50 £12 28.50 57.50 £13 31.50 63.50 £14 34.50 69.50 E15 '37.50 75.50

£16 40.50 81.50 £17 43.50 88.50 £18 46.50 93.50 £19 51.50 102.50 £20 61.50 123.50

£-99 -Write for quote N01 30.00' TABLE OF CONTENTS

Page IAA ENTRIES (A82-10000) 87 STAR ENTRIES (N82-10000) 123

Subject Index 1-1 Personal Author Index 1-51

TYPICAL CITATION AND ABSTRACT FROM STAR

NA&A aruwauMcu MVHILMDLC UN nr>fi iiuirwT I MIPRHPIPMP ll

NASA ACCESSION -•-USSR SPACE LIFE SCIENCES DIGEST. VOLUME 1. NO. 3 '—CORPORATE Ml IFiJlRFR Quarterly Review s' SOURCE -•-Patricia M Wallace Sep 1980/*41 p refs (Contract NASw-3223) -"-INASA-CR-164780! Avail'/NTIS HC A03/MF A01 CSCL PUBLICATION TITL E 06D-" DATE An overview of the developments and direction of the USSR Space Life Sciences Program is given. Highlights of launches. AUTHOR program development, and mission planning are given. Results m^ATI Topics covered include: space medicine and physiology: space CODE REPORT biology: and life sciences technology. J.M.S. NUMBER

AVAILABILITY SOURCE

TYPICAL CITATION AND ABSTRACT FROM IAA

. AVAILABLE ON -A82-11697 t The significance of the respiratory minute, -TITLE MICROFICHE volume index in the evaluation of vestibular stability (Znachenie pokazatelei minutnogo ob'ema dyknaniia pri otsenke vestibuliarnoi ustoichivostil^A. S. Gusarov. Voenno-Meditsinskii Zhurnal, Aug. - -PUBLICATION 1981, p. 48-50. In Russian. ^v. AIAA ACCESSION DATE The respiratory dynamics of persons of various vestibular NUMBER stabilities undergoing Coriolis acceleration is investigated in order to assess the possibility of using respiratory minute volume in the evaluation of vestibular function. Respiratory rate, respiratory TITLE OF AUTHOR- minute volume, heart rate and electrocardiography were monitored PERIODICAL continuously in 100 men with healthy vestibular analyzers in a 5-min test of tolerance to cumulative Coriolis forces. Changes in respiratory parameters are observed to be correlated with levels of vestibular reaction to Coriolis acceleration. Rotational and especially post- rotational vestibulospirometry and vestibulospirography are found to be the objective means of determining vestibular condition. It is concluded that the determination of respiratory minute volume taking into account other vegetative reactions appears to be a useful means of evaluating subject vestibular stability. A.L.W. AEROSPACE MEDICINE

AND BIOLOGY A Continuing Bibliography (Suppl. 232) MAY 1982

modeling and optimization of adaptive man-machine systems, includ- IAA ENTRIES ing autonomic-type systems and systems operating under critical conditions and based on idealized strategies for operative problems are examined, and the application of the concept of mutual A82-18872 t The healthy and the diseased human brain adaptation between man and machine to operator training is (Zdorovyi i bol'noi mozg cheloveka). N. P. Bekhtereva. Leningrad, considered. A.L.W. Izdatel'stvo Nauka, 1980. 208 p. 357 refs. In Russian. Conceptions of the physiological characteristics and interactions A82-19012 Physical and physiological features of long- of the human brain are discussed based on experimental and range flight and its impact on patients (Physikalische und phy- observational data obtained over nearly two decades. Current siologische Besonderheiten des Langstrekkenfluges und seine principles and capabilities in the study of the human brain are Auswirkungen auf den Patienten). K. Grossmann (Akademie des considered, including electroencephalography, electrical stimulation Sanitars- und Gesundheitswesens der Bundeswehr, Munich, West and pharmacological tests, and general principles of human brain Germany). In: Aeromedical evacuation: Results, analysis, develop- organization are reviewed particularly as regards long-term memory ments; International Aeromedical Evacuation Congress, 1st, Munich, and the maintenance of mental activity. The impact of illness on West Germany, September 16-19, 1980, Reports. general brain mechanisms is considered, along with the relation of Munich, Allgemeiner Deutscher Automobil-Club, 1981, p. 152-162. brain mechanisms to the neurophysiology of the psyche in areas such In German. as phoneme and word handling and the thinking process. Attention is Adverse effects on patients caused by long-range flights in also given to the .neurophysiology of human memory and its ambulance aircraft are presented. Various types of acceleration and electrical stimulation, and to the present arid past development of deceleration at takeoff and landing are discussed in relation to the human neurophysiology. A.L.W. possible adverse effects on respiratory patients. The effects of noise, temperature and aircraft humidity on patients are presented, and the optimal temperature is found to be 20-24 C, with an optimal aircraft A82-18977 t Biped walking - Model problems of dynamics humidity of 35%. The effects of spin, ozone, cosmic rays and and control (Dvunogaia khod'ba - Model'nye zadachi dinamiki i changes in time zone are also discussed. D.L.G. upravleniia). V. V. Beletskii. In: Motion stability. Analytical mechanics. Motion control. Moscow, Izdatel'stvo Nauka, 1981, p. 28-41. 16 refs. In Russian. A82-19014 The reliability of flight personnel during the The literature on biped walking is reviewed with emphasis on operation of the Mi-4 helicopter. Y. G. Zorbas (European Institute of the work of Beletskii and his colleagues. Particular consideration is Environmental Cybernetics, Athens, Greece). In: Aeromedical given to the method of prescribed synergy, compensating oscilla- evacuation: Results, analysis, developments; International Aero- tions, parametric optimization of the walking process, angular medical Evacuation Congress, 1st, Munich, West Germany, Septem- stabilization, stabilization algorithms, and the problem of underwater ber 16-19, 1980, Reports. Munich, Allgemeiner walking. B.J. Deutscher Automobil-Club, 1981, p. 177-180. The effect of vibration and noise of an Mi-4 helicopter on the A82-18988 t Development of an integrated walking robot reliability of the flight personnel was examined. A study group (Razrabotka integral'nogo shagaiushchego robota). D. E. Okhotsim- composed of 53 Mi-4 flight personnel was divided into work-related skii, A. K. Platonov, V. S. Gurfinkel', and E. A. Devianin. In: Motion groups which were tested for simple motor reactions, reactions to a stability. Analytical mechanics. Motion control. moving object, the critical frequency of flicker fusion, the capacity Moscow, Izdatel'stvo Nauka, 1981, p. 223-238. 30 refs. In Russian. for fine coordination of movements, and the reproducibility of The basic principles of the functional organization of an muscular exertion. The tests were applied before and after flights for integrated walking robot are reviewed. Attention is given to problems one month, and the results were compared with results from similar of motion design, the mathematical modeling of robot motion, and tests carried out on a control group manning a helicopter which had the development of laboratory jnodels. B.J. low noise and vibration levels. Significant deterioration in the performance of the tests was observed in all crewmembers on the A82-19000 Psychological problems in the mutual adapta- Mi-4, and were highest among the captains, while the control group tion of man and machine in control systems (Psikhologicheskie exhibited few of the performance degradations. It is noted that some problemy vzaimnoi adaptatsii cheloveka i mashiny v sistemakh of the declines in performance were cumulative, i.e. grew greater upravleniia). Edited by B. F. Lomov, V. F. Venda, and lu. M. with longer times. M.S.K. Zabrodin. Moscow, Izdatel'stvo Nauka, 1980. 320 p. In Russian. A systems theory and methodology is developed concerning the A82-19016 First aid for thorax traumas: Thorax drainage mutual, reciprocal adaptation of man and machine so as to optimize through suction - Report on 25 cases (Primarversorgung von the informational interaction between them. Following a review of Thoraxtraumen: Thoraxsaugdrainage - Bericht iiber 25 Fa'lle). C. current psychological problems in the man-machine system, an Biesing and A. David (Malteser-Hilfsdienst', Cologne, West Germany). approach to system optimization based on the mutual adaptation of In: Aeromedical evacuation: Results, analysis, developments; Inter- man and machine is established. Attention is then given to the national Aeromedical Evacuation Congress, 1st, Munich. West Ger- construction and modeling of processes of multilevel mutual adapta- many, September 16-19, 1980, Reports. Munich, tion of man and machine, and to psychological methods for the Allgemeiner Deutscher Automobil-Club, 1981, p. 189-191. In Ger- adaptation of specific man-machine systems. Methods for the man.

87 A82-19223

A82-19223 Evaluation of maximal and submaximal static courses for the radar positions is to be simulated. The radar displays muscle exertions. K. H. E. Kroemer (Virginia Polytechnic Institute in the scenarios require computer simulation. G.R. and State University, Blacksburg, VA) and W. S. Marras (Wayne State University, Detroit, Ml). Human Factors, vol. 23, Dec. 1981, p. A82-19258 Advanced aviation concepts evaluation 643-653. 21 refs. Contract No. F49670-79-C-0109. through computer driven simulation. J. Fabry and E. S. Stein (FAA, A model of the regulation of muscle strength exertion is Technical Center, Atlantic City, NJ). In: Summer Computer Simula- proposed. Based on the model, methods are discussed to assess tion Conference, Washington, DC, July 15-17, 1981, Proceedings. whether a subject exerts maximal or submaximal efforts. Results Arlington, VA, AFIPS Press, 1981, p. 659-661. with 40 subjects indicate that a simple technique may be developed The goals and operational characteristics of FAA programs for to judge if a subject is following instructions to exert a maximal human interactions with advanced avionics systems and displays are contraction in a routine test of voluntary muscle strength. (Author) discussed. Flight training simulators are noted to offer realistic aircraft handling experience in a cost-effective fashion. The necessity of employing human factors personnel before the actual engineering A82-19224 Differences in eye movement data recorded by of a system is stressed, and is a guiding concept in the operations of electro-oculography and cornea! reflection techniques, j. Lehtela the FAA Advanced Concepts Laboratory. The Technology, Con- (Institute of Occupational Health, Helsinki, Finland). Human Fac- cepts, and World divisions of the Laboratory are outlined, and the tors, vol. 23, Dec. 1981, p. 661-665. training simulators, the Digital Avionics Control System, and the The techniques of electro-oculography and corneal reflection are Cockpit Display of Traffic hardware are described for use by pilots compared as to their abilities to monitor saccades, fixations and and air traffic controllers. M.S.K. blinks during a visual task under simulated field conditions. Electro-oculograms and video recordings of eye mark motions were obtained simultaneously in unrestrained subjects asked to trace A82-19491 * Effects of vasopressin administration on diu- visually patterns of circles placed 1 m away. It is found that whereas resis of water immersion in normal humans. M. Epstein, A. G. the number of blinks given by the two methods coincide quite well, DelMunzio, and R. D. Loutzenhiser (U.S. Veterans Administration the number of saccades as recorded by the corneal reflection camera Medical Center; Miami, University, Miami. FL). Journal of Applied was greater- than that by EOG, due to the classification of some Physiology: Respiratory, Environmental and Exercise Physiology, shorter saccades as involuntary microsaccades in EOG recordings. vol. 51, Dec. 1981, p. 1384-1387. Research supported by the U.S. Although the exact fixation point could not be determined in the Veterans Administration; Contract No. NAS9-15473. present experiment, the fixation times calculated from EOG data The influence of vasopressin suppression on the diuresis en- appear longer than those by corneal reflection. It is concluded that countered during water immersion is investigated in studies on while the corneal reflection camera with video monitor is suitable for normal humans immersed to the neck. Six hydrated male subjects monitoring the visual situation, including the fixation point, EOG is were studied on two occasions while undergoing 6 h of immersion more suitable for providing quantitative data about blinks, saccades without or during the administration of aqueous vasopressin for the and fixations. A.L.W. initial 4 h. Neck immersion is found to result in a significant increase in urinary flow rate beginning in the first hour and persisting throughout the immersion. The administration of vasopressin A82-19225 Control and automatic processing during tasks markedly attenuated the diuretic response throughout the period of requiring sustained attention - A new approach to vigilance. A. D. infusion, while cessation of vasopressin administration during the Fisk and W. Schneider (Illinois, University, Champaign, ILK Human final 2 h of immersion resulted in a marked offset of the antidiuresis. Factors, vol. 23, Dec. 1981, p. 737-750. 34 refs. Grant No. Results thus support the view that the suppression of antidiuretic NIH-5-R01-MH-3125. NR Project 150-409. hormone contributes to the immersion diuresis of hydrated subjects. Vigilance decrements are interpreted within a two-process A.L.W. (automatic/control) theory of human information processing, and the theoretical components of the normal vigilance curve are A82-19492 * Orthostatic fluid-electrolyte and endocrine re- discussed in relation to type of processing and amount of practice. sponses in fainters and nonfainters. E. Shvartz, V. A. Convertino, L. Two experiments were conducted showing significant vigilance C. Keil, and R. F. Haines (NASA, Ames Research Center, Moffett decrements when subjects utilized effortful control processing; the Field, CA). Journal of Applied Physiology: Respiratory, Environ- normal decrement was not observed when effortless automatic mental and Exercise Physiology, vol. 51, Dec. 1981, p. 1404-1410. processing was possible. Maximum vigilance decrements occur when 39 refs. subjects must continually and redundantly allocate control- The responses to orthostasis of fluid-electrolyte and endocrine processing resources. Results disconfirm the habituation hypothesis. indicators in persons subject and not subject to fainting during tilting It is concluded that structuring a task such that there is a consistent are investigated, along with the effects of heat acclimatization and relationship between signals and noise will reduce vigilance problems. physical training on those responses. Plasma volume and electrolytes System design implications suggest that tasks should be structured to and plasma vasopressin and renin activity were determined in mimimize continuous and repetitive control processing. Methods for tilt-table tests conducted before and after an eight-day period of developing vigilance-decrement-resistant automatic processing are daily heat acclimation during exercise at 50% maximal oxygen discussed. (Author) uptake at 40 C, or a control period of exercise at 24 C. Half of the 10 subjects in the study, regardless of exercise regime, showed A82-19248 Computer simulation as a visual aid in a video improved Orthostatic reactions in the second tilting test, related to course. G. L. Bell (Mitre Corp., McLean, VA). In: Summer Computer increases in post-tilt plasma volume and potassium concentration, Simulation Conference, Washington, DC, July 15-17, 1981, Proceed- particularly in the nonfainters. In the first test, plasma renin activity ings. Arlington, VA, AFIPS Press, 1981, p. 496, is observed to increase fivefold and plasma vasopressin 50 times after 497. U.S. Department of Transportation Contracts No. FA80WA- the transition from the supine to the Orthostatic positions; the 4370; No. FA01-81-C-10001. respective increases were reduced by 50 and 75% in the second test. A study of the performance of controllers in the Air Traffic The fainters also exhibit a greater increase in vasopressin and a lower Control (ATC) system concluded that many controllers perform increase in renin activity upon tilting than the nonfainters. Results their ATC tasks in ways that leave them vulnerable to common indicate the orthostatic-induced vasopressin increase to be related to human errors, misunderstandings, and confusions. The study team volume control independent of renin activity. A.L.W. made, therefore, the recommendation that the controllers' training should include ways to compensate for basic human limitations. The A82-19493 Variability of oxygen affinity of blood - Air Traffic Service has begun to follow the recommendation by Human subjects native to high altutude. R. M. Winslow, C. C. Monge, adding videotape courses on ATC-operational remembering and N. J. Statham, C. G. Gibson, S. Charache, J. Whittembury, O. Moran, listening. Three courses (for terminal radar, en route radar, and tower and R. L. Berger (Centers for Disease Control, Atlanta, GA; cab positions) are to be provided. Each course contains ten examples Universidad Particular Peruana, Lima, Peru; National Institutes of of aids used in simulated ATC situations which are often encoun- Health, Bethesda; Johns Hopkins University, Baltimore, MD). Jour- tered by controllers. The workplace and equipment for the two nal of Applied Physiology: Respiratory, Environmental and Exercise

88 A82-19743

Physiology, vol. 51, Dec. 1981, p. 1411-1416. 24 refs. NSF Grant Kopetzky, F. Messiha, K. Light, and C. D. Barnes (Texas Tech No. INT-77-21795. University, Lubbock, TX). Journal of Applied Physiology: Respira- The oxygen equilibrium curves (OECs) of whole blood from tory, Environmental and Exercise Physiology, vol. 51, Dec. 1981, p. high-altitude natives is measured in a study of the variability of 1607-1611.33 refs. Grant No. NIH-HL-16240. oxygen affinity under in vivo conditions. An automated method was Changes in ion responses and in drug sensitivities of cardiac used to measure the entire OEC from 0 to 150 Torr under controlled muscles of animals adapted to simulated high altitude conditions are pH and C02 tension in 46 Peruvians native to high altitudes (4540 investigated. Atria isolated from young male Wistar rats acclimated m) and 25 sea-level controls. Fits of the data with the Adair curve to a simulated altitude of 6000 m and from control rats were describing the successive oxygenation of hemoglobin reveal that at a observed under normoxic conditions. The spontaneous rate of atria pH of 7.4, the oxygen tension at which the hemoglobin is half isolated from altitude-acclimated rats is found to be significantly saturated with O2 is significantly higher in the high-altitude lower than that of atria from the control animals. While neither population than in the controls. When the state of compensated group of tissues responded to the administration of ouabain, the alkalosis of the high-altitude subjects is taken into account, however, altitude-adapted atria showed a greater sensitivity to both pentobar- the values are found to be indistinguishable from the controls. It is bital sodium and to ethanol, which stopped spontaneous activity at concluded that the reduction in oxygen affinity of high-altitude lower doses than in the control animals. The acclimated atria are natives is offset by the compensatory respiratory alkalosis so that the found to be less sensitive, however, to norepinephrine and to exhibit position of the OEC is close to that of sea-level humans. Considerable a smaller chronotropic response and a greater inotropic response to individual variability in oxygen affinities is noted in both groups. increased concentrations of calcium. The data obtained are thus A.L.W. indicative of changes in tissue metabolism similar to those found in newborn animals. A.L.W. A82-19494 Glycogen and nonspecific adaptation to cold. J. LeBlanc and A. Labrie (Universite Laval, Quebec, Canada). Journal A82-19498 Breath-by-breath measurement of true alveolar of Applied Physiology: Respiratory, Environmental and Exercise gas exchange. W. L. Beaver, N. Lamarra, and K. Wasserman Physiology, vol. 51. Dec. 1981, p. 1428-1432. 14 refs. (California, University, Medical Center, Torrance, CA). Journal of Exposure to moderate cold for a few weeks causes adaptation Applied Physiology: Respiratory, Environmental and Exercise Phys- through the development of nonshivering thermogenesis primarily in iology, vol. 51, Dec. 1981, p. 1662-1675. 15 refs. the brown adipose tissue. Exposure to severe cold by repeated short A method has been developed for the on-line estimation of exposures also causes adaptation but by mechanisms that seem to be breath-by-breath alveolar gas exchange from measurements of gas different. It was also found that this type of adaptation is exchange at the mouth corrected for changes in functional residual nonspecific because it can be produced by other stresses such as capacity and alveolar gas concentration. The algorithms employed swimming or fasting. Simultaneous determinations of glycogen in the calculate alveolar 02 and C02 gas exchanges from the alveolar O2, liver and soleus and tibialis muscles indicated a possible role for this C02 and N2 concentrations at end of expiration, the volume substrate in cold resistance. Repeated cold exposure, swimming for 3 containing the lung gas stores at end of expiration and the h, or fasting for 48 h all reduced the glycogen stores when measured breath-to-breath change in this volume. Error sensitivity analysis immediately after the stress. However, the levels of glycogen were indicates the effects of inaccuracies due to measurement errors to be significantly increased above the initial values when the determina- similar in magnitude to those found in the conventional open-circuit tions were made 24 h later. Cold tolerance measured by resistance to method. Direct comparisons between the alveolar gas exchange hypothermia at -5 C was improved only when the test was done 24 h measured by the present method and according to the open-circuit after the stress had taken place. Thus, cold resistance is nonspecific assumption that inspired and expired N2 volumes are equal, in and results suggest that glycogen stores could serve as a rate-limiting subjects exercising at various work rates reveals the presence of substrate. (Author) significant breath-to-breath differences in gas exchange, particularly during metabolic and respiratory transients, which may have a A82-19495 Effect of blood volume on sweating rate and significant influence in the interpretation of the underlying physi- body fluids in exercising humans. S. M. Fortney, E. R. Nadel, C. B. ology. A.L.W. Wenger, and J. R. Bove (John B. Pierce Foundation Laboratory; Yale University, New Haven, CT). Journal of Applied Physiology: A82-19608 Psychophysical evidence for more than two Respiratory, Environmental and Exercise Physiology, vol. 51, Dec. kinds of cone in dichromatic color blindness. F. S. Frame, T. P. 1981, p. 1594-1600. 32 refs. Grant No. NIH-HL-20634. Piantanida, and D. H. Kelly (SRI International, Menlo Park, CA). Science, vol. 215, Jan. 22, 1982, p. 417-419. 11 refs. Grants No. A82-19496 Enhanced heat production in physically re- NIH-EY-02357; No. NIH-EY-01128. strained rats in hypoxia. M. Hayashi and T. Nagasaka (Kanazawa Psychophysical evidence shows that at least some classically University, Kanazawa, Japan). Journal of Applied Physiology: diagnosed dichromats have three cone types rather than two. The anomalous cones, previously thought to be absent, are less sensitive Respiratory, Environmental and Exercise Physiology, vol. 51, Dec. 1981, p. 1601-1606. 27 refs. than normal cones to both spectral and temporal variations, and have spectral sensitivities like those of the abnormal cones of anomalous The combined influence of hypoxia and restraint on metabolic heat production in rats is investigated. Heat production, heat loss, trichromats. These results are not consistent with either loss or replacement models of X-linked recessive color-vision defects, since colonic temperature and cardiovascular activity were monitored in some dichromats apparently have the same three photopigments as rats placed in individual wire mesh cages in which they could move anomalous trichromats. (Author) freely or in restraint cylinders, and exposed to mixtures of 9.5% 02 in N2 gas. Hypoxic exposure is found to lead to rapid decreases in heat production and heart rate and gradual decreases in heat loss and A82-19743 ti Staying sane in space. B. J. Bluth (California colonic temperature in the freely moving rats, while the restrained State University, Northridge, CA), Mechanical Engineering, vol. 104, r^ts exhibited increased heat production, heat loss, colonic tempera- Jan. 1982, p. 24-29. 35 refs. ture and heart rate. The increases are reversed in restrained With a view to the establishment of procedures and techniques chemically sympathectomized rats treated with 6-hydroxydopamine that will help crews adapt to long missions aboard the projected hydrobromide, while norepinephrine is observed to lead to increases NASA Space Operations Center, in which nine persons will live for in heat production and heart rate in freely moving rats. Hypoxia is between three and six months, a historical study is made of confined also found to decrease significantly blood flow to the brown adipose crew performance in isolated environments. Attention is also given to tissues in restrained rats while increasing blood flow to the heart, Soviet long-duration mission crew experience. Among the confined, diaphragm and limb muscles. Results suggest that hypermetabolism isolated and stressful precedents surveyed are Antarctic research in restrained rats during hypoxia is due to increased neurosympa- teams, submarine crews, the operators of oceanographic research thetic activity, with increased muscle metabolism. A.L.W. vessels and undersea research laboratories, and trainees in specially designed simulators. It is generally found that personality screening A82-19497 Alterations in responses to drugs of atria from prior to confinement did not accurately predict subsequent behavior, white rats acclimated to hypobaric hypoxia. M. J. Hughes, M. T. with irritability increasing as the mission progressed. NASA and

89 A82-19746

Soviet screening and training procedures are described, with recom- when 0 is more abundant than C, the NO fixation rate approaches mendations for crew compartment design. O.C. 10 to the 17th molecules/J while the HCN yield is small. The implications for the evolution of life are discussed. (Author)

A82-19746 t Brain monoamine oxidase activity during cold A82-20017 New data on abiogenic synthesis of prebiologi- adaptation and under the combined effects of cold and hyperbaric cal compounds in volcanic processes. N. E. Podkletnov and E. K. oxygenation (Aktivnosf monoaminoksidaz mozga pri kholodovoi Markhinin (Akademiia Nauk SSSR, Institut Vulkanologii, adaptatsii i sovmestnom deistvii kholoda i giperbarooksigenatsii). I. Petropavlovsk-Kamchatskiy, USSR). Origins of Life, vol. 11, Dec. A. Goroshinskaia, L. L Grabovskova, Z. G. Bronovitskaia, and A. A. 1981, p. 303-315. 13 refs. Krichevskaia (Rostovskii Gosudarstvennyi Universitet, Rostov-on- Volcanoes were deduced to be high-productive generators of Don, USSR). Fiziologicheskii Zhurnal SSSR, vol. 67, Nov. 1981, p. complex organic compounds. Ash-gas clouds produced by volcanic 1611-1616. 20 refs. In Russian. eruptions can be considered as many-kilometer chemical reactors with a wide range of temperatures and pressures, powerful electric A82-19747 t The role of extracellular O2 and CO2 tensions discharges and a large catalytic surface. In the eruption products in membrane mechanisms of cerebral arterial smooth muscle regula- investigated, nitrogen-containing components of nucleic acids of tion (Rol' P/O2/ i P/CO2/ vnekletochnoi sredy v membrannykh uracil type, metal complexes of porphyrins and porphyrins in the mekhanizmakh reguliatsii gladkikh myshts arterii golovnogo mozga). metal-free form and polycyclic aromatic hydrocarbons have been A. L. Azin (Sverdlovskii Meditsinskii Institut, Sverdlovsk, USSR). found. In all, 54 carbon-containing compounds have been identified Fiziologicheskii Zhurnal SSSR, vol. 67, Nov. 1981, p. 1652-1660. 20 in the volcanic juvenile ash and in volcanic bombs and 13 groups of refs. In Russian. carbon-containing compounds whose composition is yet unidentified have been found. (Author) A82-19748 t The temperature dependence of the kinetics of isometric myocardium relaxation (Temperaturnaia zavisimost' ki- A82-20018 Amino acids derivatives synthesis from nitro- netiki izometricheskogo rasslableniia miokarda). V. la. Izakov, B. L. gen, carbon and water by electric discharges. Y. Yamagata, Y. Bykov, and I. la. Kimmel'man (Nauchno-lssledovatel'skii Institut Kusano, and K. Inomata (Kanazawa University, Kanazawa, Japan). Gigieny Truda i Profzabolevanii, Sverdlovsk, USSR). Fiziologicheskii Origins of Life, vol. 11, Dec. 1981, p. 317-320. 9 refs. Zhurnal SSSR, vol. 67, Nov. 1981, p. 1670-1675. 11 refs. In Russian. The dependence of the exponential decay constant expressing the isometric relaxation of the myocardium on temperature is A82-20019 * The radiolysis and radioracemization of amino investigated in animals with various specific contents of myocardial acids on silica surfaces. W. A. Bonner (Stanford University, Stanford, sarcoplasmic reticulum. Experiments were performed on cardiac CA) and R. M. Lemmon (California, University, Lawrence Berkeley ventricles and atria isolated from rabbits, frogs and turtles and Laboratory, Berkeley, CA). Origins of Life, vol. 11, Dec. 1981, p. electrically stimulated to produce maximal contraction at tempera- 321-330. 25 refs. Research supported by the U.S. Department of tures from 10 to 35 C. Arrhenius plots derived from the data are Energy; Grant No. NGL-05-020-582. found to be linear in the myocardia of the rabbit and frog, with a Results are presented of experiments on the radioracemization greater activation energy for the relaxation found in the rabbit. The of amino acids in the presence of silica surfaces such as may have Arrhenius plot for the turtle, which has a sarcoplasmic reticulum been found on the prebiotic earth. L-leucine and a DL-leucine content intermediate between those of the frog and rabbit, corres- mixture deposited on samples of 1-quartz and an amorphous silica ponds to two straight lines with different activation energies. Results preparation (Syloid 63) was subjected to Co-60 gamma-ray irradia- thus support the hypothesis of two separate mechanisms of calcium tion, then analyzed by gas chromatography to determine the removal, involving the sarcoplasmic reticulum and cellular mem- radiolysis and racemization rates. The quartz surface is found to have brane, in muscle relaxation. A. L.W. a marginal efficacy in enhancing radiolysis when compared with a crystalline L-leucine control, although enhancing radioracemization A82-19749 t The influence of muscular work on the ves- symmetrically by a factor of two. Both the radiolysis and radio- tigial effects of cold acclimation (Vliianie myshechnoi raboty na racemization of L-leucine and D L-leucine on a Syloid-63 silica sledovnye effekty kholodovoi akklimatsii). V. I. Sobolev and G. I. surface are observed to increase with increasing radiation dose, and Chirva (Donetskii Gosudarstvennyi Universitet, Donetsk, Ukrainian to be substantially greater than in the crystalline controls. Additional SSR). Fiziologicheskii Zhurnal SSSR, vol. 67, Nov. 1981, p. experiments with the nonprotein amino acid isovaline deposited on 1710-1716. 17 refs. In Russian. Syloid 63 confirm the greater radiolysis susceptibility of amino acids The persistence of the vestigial effects of long-term cold deposited on silica with respect to the crystalline state, although acclimation and the effects of regular muscular work on these effects racemization is not observed. The, observations suggest that the are investigated in studies on male albino rats preliminarily exposed presence of a silica surface would have a deleterious effect on any to a temperature of 2 C for 28 days. Measurements of the calorigenic mechanism for the origin of molecular chirality relying on stereo- effect of noradrenaline, cold tolerance at -25 C, the level of working selective beta-radiolysis. A.L.W. hyperthermia and organ and tissue weights were performed on the first, tenth, 20th, and 30th days of the post-acclimation period in A82-20020 * A model for the enantiomeric enrichment of control rats and rats performing 50 min of treadwheel exercise daily. polypeptides on the primitive earth. N. E. Blair and W. A. Bonner Results indicate noradrenaline-dependent thermogenesis to be the (Stanford University, Stanford, CA). (College Park Colloquium on most persistent effect of long-term cold acclimation. Muscular Chemical Evolution, 5th, University of Maryland, College Park, MD, activity is found to accelerate the process of deacclimation due to its Oct. 31, 1980.) Origins of Life, vol. 11, Dec. 1981, P. 331-335. 24 effects on physical, and then chemical, thermoregulation. A.L.W. refs. Grant No. NGL-05-020-582. A potential model is presented for the origin of optical activity A82-20016* Rates of fixation by lightning of carbon and in polypeptides on the primitive earth due to enantiomeric enrich- nitrogen in possible primitive atmospheres. W. L. Chameides (Georgia ment in succeeding polymerization-hydrolysis cycles. The model was Institute of Technology, Atlanta, GA) and J. C. G. Walker (Michigan, developed in experiments with the polymerization of a DL-leucine University, Ann Arbor, Ml). Origins of Life, vol. 11, Dec. 1981, p. N-carboxyanhydride mixture with a 31.2% enantiomeric excess of 291-302. 35 refs. Grant No. NAG1-85; Contract No. NAGW-176. the L isomer with sodium methoxide initiator to yield a polyleucine A thermochemical-hydrodynamic model of the production of product which was in turn partially hydrolyzed by acid. The trace species by electrical discharges has been used to estimate the polymerization-hydrolysis was found to produce a net 23.8% rates of fixation of C and N by lightning in the primitive atmosphere. increase in the enantiomeric excess of the remaining unhydrolyzed Calculations for various possible mixtures of CH4, C02, CO, N2, H2, polypeptide (14.2% from the polymerization and 9.6% from the and H20 reveal that the prime species produced were probably HCN partial hydrolysis). On the basis of these results, it is suggested that a and NO and that the key parameter determining the rates of fixation slight excess produced by an appropriate chiral physical process may was the ratio of C atoms to O atoms in the atmosphere. Atmospheres be enhanced by cycles of stereoselective polymerization and hydroly- with C more abundant than 0 have large HCN fixation rates, in sis driven by fluctuating wet and dry environmental cycles on the excess of 10 to the 17th molecules/J, but small NO yields. However, primitive earth. A. L.W.

90 A82-20301

A82-20021 * Search for effect of longitudinally polarized in the text, nor is it believed that dissipation can entirely account for protons on optically active amino acids. R. M. Lemmon, H. E. the order observed in living cells. (Author) Conzett (California, University, Lawrence Berkeley Laboratory, Berkeley, CA), and W. A. Bonner (Stanford University, Stanford, A82-20025 * Could life have evolved in cometary nuclei. A. CA). Origins of Life, vol. 11. Dec. 1981, p. 337-341. 14 refs. Bar-Nun (Tel Aviv University, Tel Aviv, Israel), A. Lazcano-Araujo Contract No. W-7405-eng-48; Grant No. NGL-05-020-582. (Universidad Nacional Autonoma de Mexico, Villa Obregon, The influence of irradiation by longitudinally polarized protons Mexico), and J. Oro (Houston, University, Houston, TX). Origins of on the differential decomposition of amino acid is investigated in a Life, vol. 11, Dec. 1981, p.387-394. 66 refs. Research supported by test of the Vester Ulbricht hypothesis that L-amino acids were the Consejo Nacional de Ciencia y Tecnologia of Mexico; Grant No. produced in preference to the D isomers on the primitive earth due NGR-44-005-002. to the effects of parity violation in beta decay. Samples of The suggestion by Hoyle and Wickramasinghe (1978) that life DL-leucine were irradiated with protons of both positive and might have originated in cometary nuclei rather than directly on the negative longitudinal polarization, then analyzed by gas chromato- earth is discussed. Factors in the cometary environment including the graphy. Despite advantages of higher polarization, lower velocity and conditions at perihelion passage leading to the ablation of cometary higher ionization density of protons with respect to electrons, proton ices, ice temperatures, the absence of an atmosphere and discrete irradation is found to lead to no detectable asymmetries in liquid and solid surfaces, weak cometary structure incapable of DL-leucine degradation, even at 50% gross degradation. A.L.W. supporting a liquid core, and radiation are presented as arguments against biopoesis in comets. It is concluded that although the A82-20022 Origin of translation - The hypothesis of contribution of cometary and meteoritic matter was significant in permanently attached adaptors. S. Tyagi (Jawaharlal Nehru Univer- shaping the earth environment, the view that life on earth originally sity, New Delhi, India). Origins of Life, vol. 11, Dec. 1981, p. arose in comets is untenable, and the proposition that the process of 343-351. 29 refs. interplanetary infection still occurs is unlikely in view of the high A mechanism is proposed for the prebiotic translation of specificity of host-parasite relationships. A.L.W. polynucleotides into a sequence of amino acids fulfilling the function of a template-dependent nucleotide polymerase, based on the A82-20146 The biological effects of low-level ionizing permanent attachment of adaptors (tRNA) to nucleic acid molecules. radiation. A. C. Upton (New York, University, New York, NY). The mechanism postulates the existence of a primal tRNA with an Scientific American, vol. 246, Feb. 1982, p. 41 -49. acceptor system bearing the amino acid located near the anticodonic The hazard to human health posed by low levels of ionizing region, and with regions capaole of associating with neighboring radiation from natural and artificial sources is discussed. The natures primal tRNAs as well. The messenger-tRNA complex thus formed of the natural background radiation and man-made radiation sources would be capable of high fidelity translation with a small degree of are considered, and carcinogenic and heritable effects are identified amino acid-anticodon specificity without the need for ribosomes or as the principal health hazards associated with small doses of aminoacyl synthetases. Structural evidence supports the possibility radiation. The mechanisms of the cell damage by radiation with low of inter-primal-tRNA associations, and thermodynamic constraints and high rates of linear energy transfer are examined, with particular are compatible with the hypothesis. The approximate date of emphasis on damage to DNA resulting in chromosomal abnormali- occurrence of the proposed system is also consistent with the period ties. It is.pointed out that the frequency of chromosomal aberrations of occurrence of the earliest organisms with ribosomes. A.L.W. increases linearly with radiation dose in the low to intermediate range for both low and high energy transfer radiation, however A82-20023 A theory of the origin of life. C. B. Olson increases more quickly at high doses for the low transfer radiation. (Stanford University, Stanford, CA). Origins of Life, vol. 11, Dec. Studies of the dose-mutation rate relationship in mice and humans 1981, p. 353-368. 28 refs. are discussed which indicate that the dose required to double the A theory is developed for the functioning of the processes human mutation rate lies between 0.2 and 2.5 sieverts, along with essential to life in the primordial earth environment and the studies of cancer incidence rates which indicate the total excess of evolution of the primordial translation apparatus. Mechanisms are cancers of all types to be from 4 to 18/year per 10,000 people per proposed regarding the supply of the energy required for biological sievert. The relatively low risk associated with low levels of ionizing transfer reactions from activated compounds, nucleic acid replication radiation is discussed in relation to public perceptions and the by single template-directed bond formation and cell retention and concept of acceptable risk. A.L.W. division by environmental factors. The evolution of the nucleic acid replication process to include the synthesis of enzymes facilitating A82-20257 * Survival in space. B. Webbon (NASA, Ames replication is explained by the formation of a transfer nucleic acid which acted to catalyze the transfer of activated amino acids to Research Center, Moffett Field, CA). Natural History, vol. 90, Dec. 1981, p. 50-57. accessible amino groups. Successive steps in evolution are characterized by an increase in the number of amino acids linked together, The evolution of space suit design to meet the needs of past and future manned space missions is discussed. Following a brief and the appearance of a messenger nucleic acid to specify the consideration of the purposes of the space suit in providing an composition and sequence of the amino acids. Ribosomes would artificial atmosphere and protection from environmental hazards, arise acting to improve the translation apparatus as it became more attention is given to the first high-altitude suits developed in the complex. Finally, it is proposed that the present genetic code evolved 1930's for the protection of balloon pilots, and for high-altitude by a process of codon length refinement. A.L.W. airplane flights. The Mercury project space suit is presented as A82-20024 A neutral theory of biogenesis. A. Ferracin essentially similar to those for high-altitude military aircraft devel- (Policlinico Umberto I, Rome, Italy). Origins of Life, vol. 11, Dec. oped since World War II, providing pressurization and oxygen as a 1981, p. 369-385. 170 refs. backup to the capsule systems. Modifications to the suit allowing it The selective Darwinian theory of chemical evolution is criti- to be worn without discomfort during work outside the spacecraft, cally reviewed and the tentative conclusion is reached that neither which were stimulated by experience in Gemini missions, are the theoretical analyses nor the experiments with phages can really considered, which culminated in the suits of the Apollo and Skylab prove it. An alternative proposal is put forth which considers the programs which provided insulation, cooling and life support for possibility that the biogenetic process has been driven by stochastic periods of up to eight hours. Finally, changes to suit design made forces, e.g. it took place in the absence of Darwinian selection which, necessary by the increasing numbers of men and women to perform in turn, started only when the first protocells came into existence. Space Shuttle flights and space construction operations are consid- The dynamics of the early self-organization of living structures ered. A.L.W. should be understood in terms of self-assembly. The complexifica- tion of living matter is thus not represented as a gradual phenomenon A82-20301 t Investigation of the otolithic membrane of the but as a series of abrupt and relatively fast transitions consisting in utricle of the guinea pig (Issledovanie otolitovoi membrany utri- the aggregation of pre-systetns which had evolved by their own. The kuliusa morskoi svinki). la. A. Vinnikov, D. V. Lychakov, K. A. shift towards new and variegated states proposed by the bifurcation Koichev, A. Boiadzhieva-Mikhailova, I. Khristov, and E. A. Lavrova theory are not considered particularly relevant for reasons reported (Akademiia Nauk SSSR, Institut Evoliutsionnoi Fiziologii i Bio-

91 A82-20302

khimii, Leningrad, USSR; Meditsinska Akademiia, Pleven; B'lgarska A82-20305 t The effect of the motor activity regime on the Akademiia na Naukite, Institut po Morfologiia, Sofia, Bulgaria). development, conservation, and regeneration of defensive con- Zhurnal Evoliutsionnoi Biokhimii i Fiziologii. vol. 17, Sept.-Oct. ditioned reflexes in rats (Vliianie rezhima dvigatel'noi aktivnosti na 1981, p. 474-479. 16 refs. In Russian. vyrabotku, sokhranenie i vosproizvedenie oboronitel'nykh ustovnykh A study is presented of the structure and composition of the refleksov u krys). N. G. Zhuravleva and lu. G. Shirokov (Akademiia guinea pig otolithic membrane at various stages of development. The Nauk SSSR, Institut Vysshei Nervnoi Deiatel'nosti i Neirofiziologii, scanning and transmission electron microscopy reveal several mor- Moscow, USSR). Akademiia Nauk SSSR, Izvestiia. Seriia Biologi- phological classes of otoconia, the most common being smooth, cheskaia, Sept.-Oct. 1981, p. 790-793. 12 refs. In Russian. transitional and rough otoconia, with rhombohedral shapes less frequently encountered. The smooth and rough otoconia appear to A82-20306 t The influence of some triterpenic gly cos ides be independent morphological forms, with transition from one type on C-14-alanine inclusion into the bone-marrow cells of rats (Vliianie to the next not taking place and the numerical ratio between them nekotorykh triterpenovykh glikozidov na vkliuchenie C-14-alanina v not changing over course of development. The mean sizes of the kletki kostnogo mozga krys). N. G. Prokof'eva, lu. N. Loenko, and otoconia are observed to increase only during embryological develop- M. M. Anisimov (Akademiia Nauk SSSR, Tikhookeanskii Institut ment. A linear relation is found between otoconial length and Bioorganicheskoi Khimii, Vladivostok, USSR). Akademiia Nauk diameter. Chemical analysis reveals the presence of small amounts of SSSR, Izvestiia, Seriia Biologicheskaia, Sept.-Oct. 1981, p. 794-797. Na and Mg in addition to Ca, and trace amounts of Ca in the 20 refs. In Russian. membrane; the chemical composition does not change in the course of development. The results may be used in the study of the effects A82-20307 t Acute experimental emotional stress in rabbits of prolonged weightlessness on the vestibular apparatus of verte- in a modulated electromagnetic field (Ostryi eksperimental'nyi brates. A.L.W. emotsional'nyi stress u krolikov v usloviiakh modulirovannogo elektromagnitnogo polia). A. V. Gorbunova, N. V. Petrova, V. V. Portugalov, and S. K. Sudakov (Akademiia Nauk SSSR, Institut A82-20302 t Some indicators of carbohydrate metabolism Normal'noi Fiziologii, Moscow, USSR). Akademiia Nauk SSSR, in rat lung during repeated and chronic hypoxia (Nekotorye Izvestiia, Seriia Biologicheskaia, Sept.-Oct. 1981, p. 774-780. 15 refs. pokazateli uglevodnogo obmena v legkikh krys pri povtornoi i In Russian. khronicheskoi gipoksii). N. N. Pribylova (Khabarovskii Meditsinskii The effects of a modulated electromagnetic field on the state of Institut, Khabarovsk, USSR). Voprosy Meditsinkoi Khimii, vol. 27, emotional stress induced by alternating or combined stimulation of Sept.-Oct. 1981, p. 634-636. 26 refs. In Russian. the ventromedial nuclei of the hypothalamus and electrocutaneous The effects of prolonged chronic exposure to hypoxia on stimulation are investigated in rabbits. Experimentally stressed carbohydrate metabolism in the rat lung are investigated. Determi- animals and unstressed, restrained controls, were placed in a field of nations of glucose and glycogen levels, proteins, lactate and pyruvate intensity 30 V/m, carrier frequency 39 mHz and modulation concentrations and hexokinase and lactate dehydrogenase activities frequency 7 Hz, and arterial pressure and heart rate, water soluble were made in male and female rats following 7 and 35 days of 6-hr protein levels in various extramural autonomic and sympathetic exposures to a simulated altitude of 9000 m. The 7-day exposures ganglia, and lactate dehydrogenase isoenzyme spectra were deter- are found to be accompanied by increases in lactic acid concentra- mined. Application of the modulated electromagnetic field is found tions and the lactate/pyruvate ratio and reductions in glycogen levels, to reduce the number of rabbits susceptible to the harmful effects of indicative of the activation of the glycolitic pathway in the lung. A stresses, as well as reverse the decrease in protein content and reduction in hexokinase activity is observed associated with the eliminate the tendency towards increased aerobic metabolism in the increased glucose, possibly due to an increase in glucocorticoid cardiac conductive system. The stressed rabbits in the electromag- secretion. The decrease in hexokinase activity and increase in glucose netic field also exhibited slightly greater activities of the fast LDH content are observed to be more marked in the females than in the fractions in the superior cervical, stellate and nodose ganglia. A.L.W. males during both stages of hypoxia, which may explain the greater hypoxia tolerance of females. With longer exposure to hypoxia, it is observed that lung glycogen stores are depleted, and glucose levels A82-20308 t The functional condition of the ampullar increase paralleled by a drop in hexokinase activity. A.L.W. apparatus in Meniere's disease (Funktsional'noe sostoianie ampuliar- nogo apparata pri bolezni Men'era). Z. I. Munchaev, A. 0. Radzha- bov, and lu. 0. Bulaev (II Moskovskii Meditsinskii Institut, Moscow, A82-20303 t Physiology and pathology of respiration and USSR). Vestnik Otorinolaringologii, July-Aug. 1981, p. 7-9. 20 refs. means of correcting oxygen deficiencies in an organism /Meeting of In Russian. the Interdepartmental Commission on the Coordination of Studies in The functional characteristics of Meniere's disease are investi- Medicine of the Academy of Sciences of the Ukrainian SSR and the gated in tests involving graded threshold and subthreshold stimula- Ministry of Health of the Ukrainian SSR/ (Fiziologiia i patologiia tion of the ampullar receptors. Clinical examination of 50 patients dikhannia ta zasobi korektsii staniv kisnevogo goloduvannia organi- reveals the disease to be characterized by a definite sequence of zmu /Narada Mizhvidomchoi Komisii po Koordinatsii Doslidzhen' u injury to inner ear receptors, in the first stages involving the cochlea Galuzi Meditsini AN URSR i MOZ URSR/I. M. M. Seredenko. and ampulla and in the final stage the sacculus vestibuli. It is found Akademiia Nauk Ukrains'koi RSR, Visnik, vol. 45, Aug. 1981, p. 86. that the longer a patient has had the disease, the greater are the In Ukrainian. chances for the second ear to be affected. Threshold stimulation studies on a rotating chair reveal a decline in vestibular function, A82-20304 t EEG description algorithm for use in clinical progressing with the duration of the disease. Vestibular recruitment practice and studies of work capacity (Algoritm opisaniia EEG dlia was discovered in 73% of the cases. A.L.W. ispol'zovaniia v klinicheskoi praktike i ekspertize trudosposobnosti). A. G. Povorinskii, V. A. Zabolotnykh, and N. N. Lebedeva A82-20309 t Vestibular responses of neurons in the feline (Leningradskii Institut Ekspertizy Trudosposobnosti i Trudoustroi- anterior suprasylvian gyrus and their interaction with responses to stva Invalidov; Leningradskii Institut Usovershenstvovaniia Vrachei- acoustic and facial stimuli (Vestibuliarnye reaktsii neironov perednei Ekspertov, Leningrad, USSR). Zhurnal Nevropatologii i Psikhiatrii suprasil'vievoi oblasti kory koshki i ikh vzaimodeistvie s reaktsiiami im. S. S. Korsakova, vol. 81, no. 8, 1981, p. 1130-1133. In Russian. na zvukovoe razdrazhenie i razdrazhenie litsevogo nerva). V. S. An EEG description algorithm based on the quantitative Dem'ianenko (Akademiia Nauk SSSR, Institut Fiziologii, Leningrad, assessment of the bioelectric activity of the brain is proposed. In USSR). Neirofiziologiia, vol. 13, no. 4, 1981, p. 353-358. 9 refs. In describing a given rhythm, attention is given to its distribution, Russian. pattern, degree of distortion by other signals, the presence of generalized manifestations, and local outbreaks and paroxysms. The algorithm includes a description of the orientation reaction, re- A82-20310 t Laws governing readaptation for seamen after sponses to rhythmic and trigger photostimulation, hyperventilation, a low-latitude cruise (Nekotorye zakonomernosti protsessa readap- and pharmocological loads. The algorithm makes a more complete tatsii u moriakov posle plavaniia v nizkikh shirotakh). V. V. use of EEG information and can serve as the basis of special-purpose Berdyshev. Voenno-Meditsinskii Zhurnal, Aug. 1981, p. 50-52. In computer programs. B.J. Russian.

92 A82-20321

A82-20311 t Natural resistance of the organisms of seamen The conference on the special and clinical physiology of during postcruise rest (Estestvennaia rezistentnost' organizma moria- hypoxic states held in October 1979 at the Bogomol'tz Institute of kov vo vremia poslepokhodovogo otdykha). V. S. Novikov. Voenno- Physiology in Kiev is briefly described. Particular consideration is MeditsinskiiZhurnal, Sept. 1981, p. 51, 52. 8 refs. In Russian. given to the new classification of hypoxic states proposed by Kolchinskaia. B.J.

A82-20312 t Deontology in the practice of otorhinolaryn- A82-20318 t The measurement of oxygen and carbon gology (Deontotogiia v praktike otorinolaringologa). N. G. Chichkin. dioxide partial pressures in tissues by the gas depot method Voenno-MeditsinskiiZhurnal, Sept. 1981, p. 54, 55. In Russian. (Izmerenie partsial'nogo napriazheniia kisloroda i uglekislogo gaza v tkaniakh organizma po metodu gazovogo depo). V. L. Popkov A82-20313 t Functional condition and work capacity under (Ministerstvo Zdravookhraneniia SSSR, Institut Mediko- mountain conditions (Funktsional'noe sostoianie organizma i rabo- Biologicheskikh Problem, Moscow, USSR). Patologicheskaia Fiziolo- tosposobnost' v gornykh usloviiakh). I. D. Kudrin. R. N. Korobov, V. giia i Eksperimental'naia Terapiia, July-Aug. 1981, p. 87-89. 6 refs. A. Mozin, and V. A. Ivanov. Voenno-Meditsinskii Zhurnal, Sept. In Russian. 1981, p. 45-47. 7 refs. In Russian. The use of the gas depot method of Campbell (1926) and Van The dynamics of changes in human functional condition and Liew (1962) in the determination of the partial pressures of oxygen work capacity during the process of adaptation to middle and carbon dioxide in the tissues of an organism is discussed. The (2200-2400 m) and high (3200-3400 m) altitudes is investigated. In method involves the introduction of a gas of any composition into a persons not previously adapted to hypoxia, altitude exposure is tissue so that a gas cavity is formed which eventually comes into found to lead to decreases in work capacity as measured by the equilibrium with the gases in the surrounding tissue, followed by the accuracy of visual-motor responses, and in the quality and tempo of extraction and analysis of cavity gases. The slow response time of the professional activities, particularly those connected with intense method makes it most suitable for studies of long duration, such as physical exercise. Fatigue is found, accompanied by an impairment experiments on acclimatization over several months to altitude in cardiovascular and respiratory capacities. These changes in hypoxia, the effects of hypoxic, hypercapnic and hyperoxic breath- functional condition and work capacity are noted to be especially ing mixtures over several hours or days and prolonged hypergravity, marked in the 7 days following ascent to altitude, and to persist for where the responses of polarographic electrodes become unstable. at least 2 months. A.L.W. The gas depot method may also be used in studies of the tensions of N2 and other gases dissolved in body tissues. A.L.W. A82-20314 t Frequency characteristics of visual evoked potentials in different regions of the human cerebral cortex (Osobennosti chastotnoi struktury vyzvannykh potentsialov na svet v A82-20319 t Elevation of hypoxia resistance with the use of razlichnykh otdelakh kory bol'shogo mozga cheloveka). G. A. gutimine (Povyshenie rezistentnosti k gipoksii s pomoshch'iu guti- Shchekut'ev (Akademiia Nauk -SSSR, Institut Vysshei Nervnoi mina). V. M. Vinogradov, L. V. Pastushenkov, and E. N. Sumina. Deiatel'nosti i Neirofiziologii, Moscow, USSRI and lu. M. Koptelov Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia, July-Aug. (Akademiia Nauk SSSR, Institut Problem Upravleniia, Moscow, 1981, p. 81-85. 43 refs. In Russian. USSR). Zhurnal Vysshei Nervnoi Deiatel'nosti, vol. 31, July-Aug. Experimental data demonstrating the protection from the 1981, p. 845-847. 8 refs. In Russian. adverse effects of hypoxia offered by the antioxidant gutimine and its analogs is presented. The experiments included preliminary A82-20315 t Electroencephalographic correlates of the dif- studies of hypoxia resistance and recovery under simulated altitude, ferentiation between verbal stimuli during natural night sleep in studies of circulatory hypoxia in the brain and in intrauterine humans (Elektroentsefalograficheskie korreliaty razlicheniia sloves- fetuses, studies of myocardial ischemia during acute and chronic nykh razdrazhitelei vo vremia estestvennogo nochnogo sna chelo- experiments and studies where cardiac, kidney and limb circulation is veka). E. K. Arons and V. M. Vasil'eva (Moskovskii Gosudarstvennyi cut off. The compound was also found to be effective in cases of Universitet, Moscow, USSR). Zhurnal Vysshei Nervnoi Deiatel'nosti, hemorrhagic hypotension, complex hypoxia in peritonitis, menin- vol.31, July-Aug. 1981, p. 839-841.9 refs. In Russian. gococcal meningitis, and the weakening of uterine muscle contrac- tility during prolonged deliveries, and in cranial-cerebral trauma. Mechanisms of the antihypoxic action of gutimine and its analogs A82-20316 t The effects of narcotic analgesics on animal have been found to include the reduction of oxygen utilization, the sensitivity to hypoxia (Vliianie narkoticheskikh anal'getikov na activation of aerobic and anaerobic metabolism, the acceleration of chuvstvitel'nost' zhivotnykh k gipoksii). 8. G. Volynskii, L. A. lactate utilization, the inhibition of lipolysis in fat tissue, and Martynov, and N. S. Solun (Saratovskii Meditsinskii Institut, Saratov, stabilization of cell membranes. Clinical observations also support USSR). Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia, the experimental data. A.L.W. Sept.-Oct. 1981. p. 65-68. 14 refs. In Russian. A comparative study is presented of the effects of morphine and A82-20320 t The influence of adaptation on the periodic promedol on the sensitivity of the mouse to hypoxic hypoxia and effect of hypoxia on the poststress activation of the primary immune the state of glycolysis under conditions of oxygen insufficiency. response (Vliianie adaptatsii k periodicheskomu deistviiu gipoksii na Determinations of blood glucose, lactate, pyruvate and excess lactate poststressornuiu aktivatsiiu pervichnogo immunnogo otveta). G. T. levels, redox potentials, free energy and lactate dehydrogenase Sukhikh, B. A. Frolov, and F.Z. Meerson (Akademiia Meditsinskikh isoenzyme activities were performed in animals injected with 25 Nauk SSSR, Moscow; Orenburgskii Meditsinskii Institut, Orenburg, mg/kg morphine or promedol and exposed to a stimulated altitude of USSR). Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia, 10 km for 1 hour. Whereas morphine had no effect on survival July-Aug. 1981, p. 73-77. 8 refs. In Russian. relative to uninjected controls, promedol is observed to increase The present work studies the influence of emotional-pain stress mortality from 55 to 72%. These differences are reflected in the (EPS) on the primary immune response and lymphocyte blast effects of the two drugs on carbohydrate metabolism, with morphine transformation (LBT) in Wistar rats adapted or nonadapted to the leading to increases in blood pyruvate, redox potential and free periodic effect of hypoxia. It is found that EPS in nonadapted energy, creating favorable conditions for the oxygen utilization, animals caused intensification of the immune response, manifested in which are not found with promedol. Analysis of lactate dehydro- the number of antibody-producing cells (ABPC). The LBT indices genase isoenzyme distributions reveals that promedol favors the final did not change significantly in such cases. In animals adapted to the stage of glycolysis in organs with aerobic metabolism, while periodic effect of hypoxia the total force of the immune response morphine favors it in anaerobic organs. Finally, observations that increased but the formation of ABPC was delayed and their relative adrenalin does not induce an elevation in blood sugar levels are noted and absolute maximum values were reached on the eighth and not as evidence for the depletion of glycogen and glucose stores. A.L.W. the fifth day after immunization. The LBT was reduced by 33.4-52.4% as compared with that in nonadapted animals. B.J. A82-20317 t Special and clinical physiology of hypoxic states (Spetsial'naia i klinicheskaia fiziologiia gipoksicheskikh sosto- ianii). M. M. Filippov. Patologicheskaia Fiziologiia i Eksperimen- A82-20321 t A combined method for the study of tissue tal'naia Terapiia, July-Aug. 1981, p. 91, 92. In Russian. respiration under conditions corresponding to natural gas homeo-

93 A82-20322

stasis (Kombinirovannyi metod izucheniia tkanevogo dykhaniia v (Akademiia Nauk SSSR, Nauchno-lssledovatel'skii Institut Fiziologii, usloviiakh estestvennogo gazovogo gomeostaza). E. S. Mailian, E. A. Leningrad, USSR). Fiziologiia Cheloveka, vol. 7, July-Aug. 1981, p. Kovalenko, and L. B. Buravkova. Patologicheskaia Fiziologiia i 616-622. 25 refs. In Russian. Eksperimental'naia Terapiia, July-Aug. 1981, p. 85-87. 6 refs. In The effects of supplementary respiratory resistance on pulmo- Russian. nary ventilation and inspiratory muscle work during the progressively A method based on a combination of the Warburg flask with a increasing hypercapnia are investigated. Measurements of inspiratory polarographic electrode has been developed for the study of tissue flow velocity and intrasternal pressure and calculations of ventilation respiration which enables the oxygen tension in the incubation and inspiratory work were performed for awake subjects exposed to medium to be maintained at levels corresponding to those in the in 12, 20 and 28 cm H20/I per sec during controlled alveolar vivo tissue. The polarographic electrode placed in the flask is used to hypercapnia. Resistive loading is shown to reduce ventilatory monitor the oxygen tension in the incubation medium, while the reactions to CO2, and induce a more rapid increase in inspiratory manometer of the Warburg apparatus measures the respiration rate muscle work that is not proportional to the magnitude of the under the prescribed oxygen tension. The combined method has increased resistance. The characteristics of the ventilatory response been used to measure tissue respiration in rats following exposure to are indicative of cortical influences. A.L.W. slowly increasing hypoxia and to combined hypoxia and hypercapnia. When compared to experiments performed in air, the A82-20328 t The role of biofeedback in the adaptive variations in the oxygen consumption of brain tissue homogenates regulation of pathological bioelectric brain activity (Znachenie taken from animals at three stages of hypoxia exhibit more marked obratnoi sviazi pri adaptivnom regulirovanii patologicheskoi bioelek- variation, becoming greatest at the second stage (70-50 mm Hg). tricheskoi aktivnosti mozga). A. A. Vereshchagina (Akademiia Nauk A.L.W. SSSR, Institut Fiziologii, Leningrad, USSR) and E. A. Kaidanova (Akademiia Meditsinskikh Nauk SSSR, Leningrad, USSR). Fiziolo- A82-20322 t Contractile dysfunction of vascular wall giia Cheloveka, vol. 7, July-Aug. 1981, p. 579-585. 12 refs. In smooth muscle undSr emotional nociceptive stress (Narusheniia Russian. sokratitel'noi funktsii gladkoi myshtsy sosudistoi stenki pod vliianiem emotsional'no-bolevogo stressa). F. Z. Meerson, M. I. Gurevich, A82-20329 t The effects of an aqueous potassium loading S. A. Bershtein, A. I. Solov'ev, V. A. Saltykova, and O. V. Baziliuk test on kidney function (Vliianie vodno-kalievoi nagruzochnoi proby (Akademiia Meditsinskikh Nauk SSSR, Moscow, USSR; Akademiia na funktsiiu pochek). R. I. Aizman (Novosibirskii Gosudarstvennyi Nauk Ukrainskoi SSR, Institut Fiziologii, Kiev, Ukrainian SSR). Pedagogicheskii Institut, Novosibirsk, USSR). Fiziologiia Cheloveka, Kardiologiia, vol. 21, Aug. 1981. p. 108-110. 9 refs. In Russian. vol. 7, July-Aug. 1981, p. 687-692. 26 refs. In Russian. Normal human kidney functioning in response to aqueous potassium loading is investigated with particular attention given to A82-20323 t Changes in microcirculatory flow with respira- the specificity of the potassiouretic response. Blood and urine tory insufficiency (Izmeneniia mikrotsirkuliatornogo krovo- samples were taken from 28 healthy subjects before and after loading obrashcheniia pri dykhatel'noi nedostatochnosti). 0. V. Aleksandrov, with 50 mg KCI/kg body weight in a 20% aqueous solution, or water I. S. Ezhova, R. M. Alekhina, lu. A. Gubin, V. N. Raibman, S. M. alone. The ingestion of KCI, while not inducing any variation in Larionov, I. I. Savchenkov, and A. M. Shenshina (II Moskovskii circulatory cation concentrations, is found to cause a two-phase Meditsinskii Institut, Moscow, USSR). Kardiologiia, vol. 21, Aug. diuretic reaction, a marked increase in potassium excretion, and a 1981, p. 95-100. 15 refs. In Russian. shorter-duration and lower elevation in natriuresis as compared with the controls. The magnitude of the potassiouretic reaction is A82-20324 t Microcirculation, tolerance to physical strain, observed to depend on the initial level of ion excretion. Results and certain homeostasis parameters in patients with angina pectoris suggest the presence of a reflex mechanism of potassium balance, and (Mikrotsirkuliatsiia, tolerantnost' k fizicheskoi nagruzke i nekotorye demonstrate specificity in kidney ionouretic responses. A.L.W. pokazateli gomeostaza u bol'nykh so stenokardiei). V. V. Anikin and V. V. Trotsiuk (Kalininskii Meditsinskii Institut, Kalinin, USSR). Kardiologiia, vol. 21, Aug. 1981, p. 92-95. 6 refs. In Russian. A82-20330 t Investigation of recurrent inhibition in the human spinal cord during static skeletal muscle activity (Issledovanie vozvratnogo tormozheniia v spinnom mozge cheloveka pri statiche- A82-20325 t Models of a functional lapse in one hemisphere skoi deiatel'nosti skeletnykh myshts). I. N. Pleshchinskii and V. I. and of the neuropharmocological effects on the deep structures of Alatyrev (Kazanskii Gosudarstvennyi Universitet, Kazan, USSR). the brain (Model! funktsional'nogo vykliucheniia odnogo polushariia Fiziologiia Cheloveka, vol. 7, July-Aug. 1981, p. 737-742. 17 refs. In i neirofarmakologicheskikh vozdeistvii na glubokie struktury mozga). Russian. V. V. Menshutkin (Akademiia Nauk SSSR, Institut Evoliutsionnoi The characteristics of recurrent inhibition in the human spinal Fiziologii i Biokhimii, Leningrad, USSR), T. P. Suvorova (Akademiia cord during and after static activity of the skeletal muscles are Nauk SSSR, Institut Fiziologii, Leningrad, USSR), and L. la. investigated. Determinations were made of the relation of the Balonov (Psikhiatricheskaia Bol'nitsa, Leningrad, USSR). Fiziologiia amplitudes of the H responses of the soleus muscle obtained during Cheloveka, vol. 7, Sept.-Oct. 1981, p. 880-888. 23 refs. In Russian. paired and single stimulation of the tibial nerve by stimuli of various intensities in subjects exerting force on a foot pedal. Static muscle A82-20326 t The use of linear models for EEG analysis activity is found to be accompanied by a reduction in the recurrent (Ispol'zovanie lineinykh modelei dlia issledovaniia EEG). V. K. inhibition of the motoneurons innervating the muscle. Cessation of Bochkarev and A. I. Nikiforov (Akademiia Meditsinskikh Nauk the muscle work leads to an initial decline in motoneuron reflex SSSR, Moscow, USSR). Fiziologiia Cheloveka, vol. 7, Sept.-Oct. excitability and enhancement in recurrent inhibition, which is 1981, p. 868-879. 36 refs. In Russian. followed by an elevation in excitability as the inhibition continues to The method of main components and the method of canonical increase. Muscle rest during analogous activity of opposing muscles correlations are used to study the organization of the background induces less marked changes in motoneuron excitability, and no EEG of healthy subjects and those suffering from paranoid schizo- response in the level of recurrent inhibition. In addition, voluntary phrenia. Nonspecific forms of EEG organization are obtained which muscular activity in one extremity is found not to influence neural reflect the state of the activating and synchronizing mechanisms of activity in the spinal center of the other extremity. A.L.W. the brain. These forms of organization were found to be informative with respect to the action of neuroleptics, and can be used in the A82-20331 t Pulse rate evaluation of the relative physiologi- prognosis of the effectiveness of therapy on a statistically confident cal intensity of aerobic muscular work (Pul'sovaia otsenka otnosi- level. Forms of EEG organization which correlate with psychopatho- tel'noi fiziologicheskoi napriazhennosti aerobnoi myshechnoi ra- logical disorders are also obtained. B.J. boty). V. M. Alekseev and la. M. Kots (Gosudarstvennyi Tsentral'nyi Institut Fizkul'tury, Moscow, USSR). Fiziologiia Cheloveka, vol. 7, A82-20327 t The significance of airflow resistance to July-Aug. 1981, p. 728-736. 20 refs. In Russian. changes in responses to increasing hypercapnia (O rnachenii rezistiv- Relations between absolute and relative indicators of heart rate nogo soprotivleniia v izmeneniiakh reaktsii na narastaiushchuiu and oxygen uptake as measures of physiological work intensity are giperkapniiu). M. A. Pogodin, A. M. Shmeleva, and E. L. Kalacheva investigated in athletes and nonathletes during aerobic muscular

94 A82-20539

activity. Bicycle ergometer exercise at the same absolute aerobic Nauk SSSR, Laboratoriia Funktsional'noi Neirokhimii, Leningrad, Power (equal oxygen uptake) is found to be accompanied by USSR). Fiziologicheskii Zhurnal SSSR, vol. 67, Sept. 1981, p. different absolute exercise heart rates in subjects with different 1324-1328. 20 refs. In Russian. characteristic maximal oxygen uptakes and maximal heart rates. In work at the same relative aerobic power (percentage of maximal oxygen uptake equal), the differences in exercise heart rates between A82-20337 t The myenteric plexus - Basic principles of groups are reduced, and are a function primarily of maximal heart modeling neuronal organization (Mienteral'noe spletenie - Bazisnye rate and heart rate reserve (the difference between actual and printsipy modelirovaniia neironnoi organizatsii). A. V. Gnetov, A. D. maximal rates). Relative pulse rate indicators (percentage maximal Nozdrachev, and S. V. Reiman (Akademiia Nauk SSSR, Laboratoriia rate and exercise increase) remained approximately the same at equal Fiziologii Vegetativnoi Nervnoi Sistemy, Leningrad, USSR). Fiziolo- relative aerobic powers in subjects of different capacities. It is gicheskii Zhurnal SSSR. vol. 67, Aug. 1981, p. 1268-1272. 11 refs. concluded that the percent maximal heart rate and the relative In Russian. increase in heart rate are the most suitable indicators of the Comparative physiological intensities of aerobic work. A.L.W. A82-20S29 Flight simulation - The military need. P. D. M. Moore (RAF, London, England). In: Experience and needs of civil A82-20332 t Parameters of the interaction of bradykinin and military flight simulator users; Proceedings of the Flight with cardiovascular system receptors (Parametry vzairnodeistuiia Simulation Symposium, London, England, April 7, 8, 1981. bradikinina s retseptorami serdechno-sosudistoi sistemy). V. I. London, Royal Aeronautical Society, 1981. 4 p. Kiselev and A. L. Panchenko (Altaiskii Meditsinskii Institut, Barnaul, Military applications of simulators for helicopter and jet pilot USSR). Fiziologicheskii Zhurnal SSSR, vol. 67, Sept. 1981, p. training are reviewed. Experience in simulators which mock the VC 1342-1347. 12 refs. In Russian. 10, Hercules, and Nimrod helicopters is intended to eliminate much A quantitative investigation is presented of cardiovascular airborne training, noting that simulation of all known threat radars is receptor stimulation by bradykinin to produce a lowering of arterial now possible. Although the RAF currently uses 23 simulators for jet Pressure. Dose-response curves were constructed to express the flight, emphasis is placed on the fact that the simulators allow relation between intravenous and intraarterial injections of brady- practice at emergency conditions, procedures, and instrumentation, kinin and arterial pressure in dogs and albino rats. The resulting while only with new Tornado simulators will there be full handling equation is found to resemble that obtained describing depressor capability simulation. The use of g seats, the length of an adrenergic and certain cholinergic reactions. The greatest hypotensive acceleration impulse, and the possibilities for full-image motion response to bradykinin injection is obtained when the peptide is generation by computer are discussed. The instructor's instrument administered intraaortically, and the kininergic reaction is noted to panel is criticized, and suggestions are made for improving switch be significantly more pronounced in dogs than in rats. A.L.W. spacing, more accurate feedback instrumentation from the trainee's panel, and a more advantageous viewing position. M.S.K. A82-20333 t Changes of the aggregation and orientation structure of blood in pulsating flow (Ob izmenenii agregatsionnoi i A82-20534 Flight simulation in the current Australian orientatsionnoi struktury krovi pri pul'siruiushchem techenii). V. A. airline scene. A. R. Gray (Transport Australia, Australia). In: Levtov, N. I. Nikiforuv, and N. Kh. Shadrina (Akademiia Nauk Experience and needs of civil and military flight simulator users; SSSR, Laboratoriia Fiziologii Krovoobrashcheniia, Leningrad, Proceedings of the Flight Simulation Symposium, London, England, USSR). Fiziologicheskii Zhurnal SSSR, vol. 67, Sept. 1981, p. April 7, 8, 1981. London, Royal Aeronautical 1336-1341. 8 refs. In Russian. Society, 1981. 7 p. Reflection photometry was used to investigate erythrocyte The use of simulators by the two nationally and one interna- suspensions in a rigid glass tube in an effort to examine structural tionally franchised Australian airlines is described. The simulators for changes of blood as a function of hydrodynamic pulsation fre- 747 aircraft flying are considered to be sufficient for credit for all quency. It is shown that the aggregation-orientation structure of the air-work sequences, for engine failure in take-off, and for all erythrocytes distinctly changes as a function of the hydrodynamic instrument flight sequences and two- and three-engine approaches, Oscillation frequency of blood flow within the range of natural heart but not for landing and flare. Accreditation levels for the internal rate. B.J. operators are reviewed, noting that thus far no pilot has received landing credits in a simulator, and the near term arrival of six A82-20334 t Bioenergetic characteristics of various kinds of degrees-of-freedom simulators with wraparound visuals is mentioned. physical loads (Bioenergeticheskaia kharakteristika fizicheskikh nag- Personnel isolation and formal radio conversations are used to ruzok razlichnogo kharaktera). S. V. Usik and R. I. Lenkova maintain the fidelity of the simulations, and pilots are frequently (Leningradskii Nauchno-lssledovatel'skii Institut Fizicheskoi Kul'- employed to judge the effectiveness of the simulators in giving the tury, Leningrad, USSR). Fiziologicheskii Zhurnal SSSR, vol. 67, actual feel of a real aircraft. M.S.K. Sept. 1981, p. 1370-1374. 12 refs. In Russian. Bioenergetic characteristics of physical loads of various intensi- A82-20538 Visual technology and the future. D. Shorrock ties and durations were obtained from experiments on adult white (Redifon Simulation, Inc., Arlington, TX). In: Experience and needs rats. These characteristics were used to classify the loads with respect of civil and military flight simulator users; Proceedings of the Flight to the character of the energy maintaining muscle activity and the Simulation Symposium, London, England, April 7, 8, 1981. Use of hydrocarbon and nonhydrocarbon sources of energy. This London, Royal Aeronautical Society, 1981. 4 p. approach can be used to evaluate the character and degree of The development of visual reproductions with high realism adaptation of animals subjected to various types of loads. B.J. fidelity for flight simulators is traced, and attention is given to regulatory requirements. Computer generated imagery reached the A82-20335 t Functional condition of the rat sympato- stage of two-window, full color landing maneuvers in about 1980, adrenal system during emotional and nociceptive stress (Funktsio- and the 747 simulator features four-window, three channel projec- nal'noe sostoianie simpato-adrenalovoi sistemy keys pri tion, in line with FAA Phase II requirements. Flight through low emotsional'no-bolevom stresse). B. N. Manukhin, V. I. Pavlova, T. G. cloud layers and the matching of a variable coefficient of friction to Putintseva, E. V. Volina, L. V. Berdysheva, G. D. Kurbanova, G. P. visual representation of a contaminated runway are reviewed, and a Selivanova, and F. Z. Meerson (Akademiia Nauk SSSR, Laboratoriia Fiziologii; Akademiia Meditsinskikh Nauk SSSR, Moscow; Chelia- distinction is made between the necessities of normal flight training binskii Gosudarstvennyi Pedagogicheskii Institut, Chelyabinsk, simulators and the task-oriented complexities of military simulators. USSR). Fiziologicheskii Zhurnal SSSR, vol. 67, Aug. 1981, p. The installation of redundant architecture and parallel processing 1182-1188. 16 refs. In Russian. units in a modular approach to simulator computer design is asserted to be the means for highly complex, realistic. Phase III simulators. M.S.K. A82-20336 t Respiration of brain synaptosomes under conditions of depolarization in rats deprived of paradoxal sleep (Dykhanie sinaptosom golovnogo mozga krys, lishennykh paradoks- A82-20539 The semi-automatic instructional system. W. S. al'noi fazy sna, v usloviiakh depoliarizatsii). N. S. Nilova (Akademiia Reese and R. A. Hansen (Singer Co., Link Div., Binghamton, NY).

95 A82-20772

In: Experience and needs of civil and military flight simulator users; for panspermia, limits to life posed by extreme environments, and Proceedings of the Flight Simulation Symposium, London, England, the status of cometary space missions as of 1980. A.L.W. April 7, 8, 1981. London, Royal Aeronautical Society, 1981. 17 p. The requirements and operational characteristics of the B-52 A82-20863 Chemical evolution of interstellar dust - A Weapon System Trainer are discussed. The WST has functional source of prebiotic material. J. M. Greenberg (Leiden, Rijksuniver- simulation for six crew members in two groups of three, with six siteit, Leiden, Netherlands). In: Comets and the origin of life; degrees-of-freedom and the option of separate operation by any Proceedings of the Fifth College Park Colloquium on Chemical two-man team in their own segment. Noting that many of the WST Evolution, College Park, MD, October 29-31, 1980. functions cannot be performed for practice on board the aircraft, the Dordrecht, D. Reidel Publishing Co., 1981, p. system has been designed to easily accommodate changes in the 111-127. 12 refs. Research supported by the Stichting voor weapons and avionics of the actual B-52. Provisions have been made Fundamenteel Onderzoek der Materie and Nederlandse Organisatie for instructor data gathering and scoring of trainee performance, and voor Zuiver-Wetenschappelijk Onderzoek. the requirements for software development are outlined. The The chemical evolution of interstellar matter is examined in instructor is provided with a three module console with access to the relation to the possibility of an extraterrestrial origin for prebiotic views being displayed in the WST, and is given broad selection in molecules. Theoretical and laboratory studies of the chemical choosing the flight environment to which the trainees are subjected. evolution of interstellar dust grains are summarized which indicate a M.S.K. chemical composition at the time of the early pre-solar nebula of complex nonvolatile molecular mixtures of oxygen, carbon and nitrogen with hydrogen in addition to volatiles, which may be the A82-20772 ff Working in space. G. V. Butler (McDonnell predominant constituents of an accreting comet. The photoprocess- Douglas Astronautics Co., Huntington Beach, CA). Research spon- ing of interstellar material is found capable of converting on the sored by the American Institute of Aeronautics and Astronautics. order of 10% of all available carbon, oxygen and nitrogen into large New York, American Institute of Aeronautics and Astronautics molecules after 10 million years. Consideration of the possible (AIAA Aerospace Assessment Series. Volume 5), 1981. 134 p. 17 mechanisms for the transport of interstellar organic molecules to the refs. Members, $20; nonmembers, $24. primitive earth indicates that direct accretion during the passage of The developing capability of human beings to work in space are the solar system through a dense interstellar cloud is a more likely examined, with consideration given to the lessons learned from source of prebiotic molecules than accretion from cometary material. previous U.S. and Soviet space missions. Noting the innovative A.L.W. measures taken by the crewmembers of the Apollo 13 flight to avert disaster, the equipment and procedures for spending extended periods of time in space which were developed and tested during the A82-20864 Comets and the origin of life - The stable Skylab and Salyut missions are reviewed. Repairs were effected on isotope approach. P. I. Abell (Cambridge University, Cambridge, the Skylab solar panels and psychological and physical requirements England; Rhode Island, University, Kingston, Rl), A. E. Fallick, N. J. were defined, as were spacecraft re-entry profiles when the Skylab McNaughton, and C. T. Pillinger (Cambridge University, Cambridge, finally came down. The functions and the experimental packages England). In: Comets and the origin of life; Proceedings of the Fifth designed for the Space Shuttle are described, with particular College Park Colloquium on Chemical Evolution, College Park, MD, attention given to the equipment intended to provide a greater range October 29-31, 1980. Dordrecht, D. Reidel of activity and usefulness for space activities. Finally, projections are Publishing Co., 1981, p. 129-139. 31 refs. Research supported by the made for future, expanded space missions, including the construction Science Research Council, Natural Environment Research Council of of large space structures, the use of manned orbit transfer vehicles, England, and Nuffield Foundation. and the colonization of space and the moon. M.S.K. An improved knowledge of the carbon isotopic composition of comets would be important in the establishment of links between A82-20778 ff Flow visualization techniques in medical and comets and the origin of life on earth. The paper presents suggestions biological applications. W.-J. Yang (Michigan, University, Ann Arbor, concerning a possible method for measuring stable isotope ratios in Ml). In: International Symposium on Flow Visualization, Bochum, presumed terrestrial cometary debris or in situ. The method under West Germany, September 9-12, 1980, Preprints of Contributed development for carbon isotope measurements on Brownlee particles Papers. Bochum, West Germany, Ruhr- collected in the stratosphere involves static mass spectrometry with Universitat Bochum, 1981, p. 13-25. 60 refs. all carbon samples converted to CD4 by a gas phase process using D2 The application of flow visualization techniques to medicine, and a nickel catalyst. A cometary isotope front end reactor is also pharmacology, and biology are reviewed. Contrast media, in liquid or under development which would perform the same function on a gas state, or as fine particles suspended in solution, are used to space probe on a cometary fly-by mission. A.L.W. intensify the image in contrast to its surrounding tissues through dyes, fluorescein, radioactive contrast media, and radioisotope- labeling. Dyes and optical methods are used most often, whereas A82-20865 * Are comets connected to the origin of life. A. photography and radiology are commonly used in either a single or H. Delsemme (Toledo, University, Toledo, OH). In: Comets and the sequential recordings. The morphology and functions of many origin of life; Proceedings of the Fifth College Park Colloquium on biological systems may be observed by the unaided eye or with the Chemical Evolution, College Park, MD, October 29-31, 1980. aid of an optical instrument. A magnified image may also be Dordrecht, D. Reidel Publishing Co., 1981, p. produced by either (1) photographic or optical magnification; (2) 141-159. 27 refs. NSF Grant No. AST-80-18919; Grant No. direct geometric magnification; or (3) electronic magnification. J.F. NsG-7381. Possible connections between comets and the origin of life on A82-20853 * Comets and the origin of life; Proceedings of earth are discussed. The orbital evolution of comets and their origin the Fifth College Park Colloquium on Chemical Evolution, Univer- are considered within a framework for the origin of the solar system, sity of Maryland, College Park, MD, October 29-31, 1980. Collo- with particular attention given to the origin of the biosphere, and the quium supported by NASA. Edited by C. Ponnamperuma (Maryland, origin of the Oort cloud. Evidence suggesting that cometary nuclei University, College Park, MD). Dordrecht, D. Reidel Publishing Co., are undifferentiated throughout is considered, and a model of the 1981. 287 p. $39.50. average composition of a mean new comet is obtained from observational data which is similar to that of an interstellar frost. The Papers are presented concerning the characteristics of comets chemistry of the model composition giving rise to the species and their possible role in the origin of life. Specific topics include the observed in cometary spectra is considered, as well as the relations of characteristics, origin and structure of the cometary nucleus, cometary to cosmic abundances of oxygen, carbon and sulfur. The cometary chemical abundances, the nature of interplanetary dust and characteristics of possible sites for prebiotic chemistry, including its entry into terrestrial planet atmospheres, and the mechanism of interstellar clouds, the protosolar nebula, comets in the Oort cloud, ray closure in comet tails. Attention is also given to chemically periodic comets and the primitive earth, are examined, and a possible evolved interstellar dust as a source of prebiotic material, the relation role of comets in bringing the interstellar prebiotic chemistry to of comets to paleoatmospheric photochemistry, comets as a vehicle earth is suggested. A.L.W.

96 A82-20901

A82-20866 * Comets and the photochemistry of the paleo- and the origin of life; Proceedings of the Fifth College Park atmosphere. J. S. Levine, R. E. Boughner (NASA, Langley Research Colloquium on Chemical Evolution, College Park, MD, October Center, Hampton, VA), T. R. Augustsson (Old Dominion University, 29-31, 1980. Dordrecht, D. Reidel Publishing Norfolk, VA), M. Natarajan (Joint Institute for Advancement of Co., 1981, p. 241-248. 24 refs. Flight Sciences, Hampton, VA), and L. J. Sacks (Christopher Limits to the environments in which microorganisms can survive Newport College, Newport News, VA). In: Comets and the origin of and grow are considered in relation to the possibility of the existence life; Proceedings of the Fifth College Park Colloquium on Chemical and evolution of life on comets. Microbial growth in boiling and Evolution, College Park, MD, October 29-31, 1980. freezing water, conditions of high salinity, extreme acidity and Dordrecht, D. Reidel Publishing Co., 1981, p. alkalinity up to pH 11.5 and high radiation is discussed, and it is 161-190. 56 refs. noted that the mechanisms of life under these extreme conditions Ozone (03) is a key atmospheric gas in considerations of the appear similar to those under more normal conditions. It is observed photochemistry/chemistry of the paleoatmosphere, chemical evolu- that all growth requires relatively abundant amounts of liquid water, tion, and the origin and evolution of life. The photochemistry/ as growth does not take place within ice or water activities below 0.6 chemistry of atmospheric 03 in the paleoatmosphere is investigated although organisms may survive much drier or colder conditions. It is using a one-dimensional photochemical model that includes the concluded that unless comets have substantial zones of liquid water, chemistry of oxygen, nitrogen, hydrogen, carbon, and chlorine gases. terrestrial-type life cannot exist or arise there. A.L.W. The role of cometary influx of H20 on the photochemistry of the paleoatmosphere is also examined. Recently, it has been suggested A82-20871 * Comets and the origin of life - Bibliography. L. that the planet received a significant portion of the volatiles G. Pleasant (George Washington University, Medical Center, Washing- presently in the atmospheric/oceanic/biospheric system from come- ton, DC). In: Comets and the origin of life; Proceedings of the Fifth tary volatile influx. Several consequences of a cometary H2O influx College Park Colloquium on Chemical Evolution, College Park, MD, on the photochemistry and structure of the paleoatmosphere are October 29-31, 1980. Dordrecht, D. Reidel presented. (Author) Publishing Co., 1981, p. 255-268. 168 refs. Contract No. NASw- 3165. A82-20867 * Cometary material and the origins of life on earth. A. Lazcano-Araujo (Universidad Nacional Autonoma de Mexico, Villa Obregon, Mexico) and J. Oro (Houston, University, A82-20891 Measurement of radio frequency permittivity Houston, TX). In: Comets and the origin of life; Proceedings of the of biological tissues with an open-ended coaxial line. I. T. W. Athey Fifth College Park Colloquium on Chemical Evolution, College Park, (U. S. Food and Drug Administration, Bureau of Radiological MD, October 29-31, 1980. Dordrecht, D. Reidel Health, Rockville, MD), M. A. Stuchly (Department of National Publishing Co., 1981, p. 191-225. 160 refs. Research supported by Health and Welfare, Radiation Protection Bureau; Ottawa, Univer- the Consejo Nacional de Ciencia y Tecnologia; Grant No. sity, Ottawa, Canada), and S. S. Stuchly (Ottawa, University, NGR-44-005-002. Ottawa, Canada). IEEE Transactions on Microwave Theory and The role of cometary material in determining the environmental Techniques, vol. MTT-30, Jan. 1982, p. 82-86. 11 refs. Research conditions of the prebiotic earth is reviewed. The organic synthesis supported by the Natural Sciences and Engineering Research Council pathways that occur in dense interstellar clouds and in comets are of Canada and Ontario Ministry of Labor. examined, and complex organic molecules believed to exist (amino acids, carboxylic acids, purines, pyrimidines and hydrocarbons) A82-20892 Measurement of radio frequency permittivity based on spectral detections of degradation products are noted. of biological tissues with an open-ended coaxial line. II - Experi- Estimates of the amount of terrestrial volatiles of cometary origin mental results. M. A. Stuchly (Department of National Health and that may have been acquired in collisions during the early history of Welfare, Radiation Protection Bureau; Ottawa, University, Ottawa, the earth are considered, and shown to dominate any estimated Canada), T. W. Athey (U.S. Food and Drug Administration, Bureau contributions to terrestrial carbon from other extraterrestrial of Radiological Health, Rockville, MD), G. M. Samaras, and G. E. sources. Current evidence that the origin and early evolution of life Taylor (Maryland, University, Baltimore, MD). IEEE Transactions on began about four billion years ago is discussed in relation to the Microwave Theory and Techniques, vol. MTT-30, Jan. 1982, p. cometary bombardment processes occurring at the time and the 87-92. 9 refs. resultant shock waves, reducing atmospheres and reactive chemical species. It is thus concluded that comets contributed significantly to A82-20893 Waveguide technique for the calibration of the processes of chemical evolution necessary for the emergence of miniature implantable electric-field probes for use in microwave- life on earth. A.L.W. bioeffects studies. D. A. Hill (Defence Research Establishment, Protective Sciences Div., Ottawa, Canada). IEEE Transactions on A82-20868 Comets - A vehicle for panspermia. F. Hoyle Microwave Theory and Techniques, vol. MTT-30, Jan. 1982, p. and C. Wickramasinghe (University College, Cardiff, Wales). In: 92-99. 17 refs. Comets and the origin of life; Proceedings of the Fifth College Park Colloquium on Chemical Evolution, College Park, MD, October 29-31, 1980. Dordrecht, D. Reidel Publishing A82-20901 Origin of life; Proceedings of the Third ISSOL Co., 1981, p. 227-239. 12 refs. Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, Arguments are presented for the panspermia hypothesis, accord- 1980. Meetings sponsored by the International Society for the Study ing to which life is a phenomenon inherent in the cosmos, and for of the Origin of Life, Israel Academy of Sciences and Humanities, the role of comets in the transport, amplification and dispersal of life Weizmann Institute of Science, and Hebrew University of Jerusalem. throughout the universe. Panspermia is shown to be a consequence of Edited by Y. Wolman (Jerusalem, Hebrew University, Jerusalem, the observation that life is always derived from life, which Israel). Dordrecht, D. Reidel Publishing Co., 1981. 626 p. $73.50. observation is supported by the fossil record up to 3.83 billion years Papers are presented on various aspects of the origin of life as ago, when the Isua sediments were deposited. Problems with the they relate to interstellar molecules, meteorites, the abiotic synthesis probability of specifying the information necessary for living of small molecules, prebiotic polymerization, the origin of optical processes from an initially chaotic assemblage of biological activity and the genetic code, early biochemical evolution, and monomers are discussed as evidence that life could not have arisen fossils. Specific topics include the origin of organic molecules in independently on earth, and astronomical evidence for the possibility interstellar space, the role of comets in the origin of life, the of the interstellar dispersal of spores is noted. It is argued, however, nitrogenous compounds in carbonaceous meteorites, the role of UV that a more efficient process for the amplification and dispersal of light and electric discharges in the chemical evolution of a reducing atmosphere, the role of clays as prebiotic photocatalysts and the life on a cosmic scale would be .development and transport within comets. It is also shown that the properties of interstellar extinction formation of amino acids from sugars and ammonia in an ocean medium. Attention is also given to metal ion catalysis of the may be explained by the bacterial nature of the interstellar grains. template-directed synthesis of oligoguanylic acids, the cold theory of A.L.W. the origins of life, the amplification of optical activity by crystalliza- A82-20869 Extreme environments - Are there any limits tion processes, evolutionary processes of the genetic code, a search to life. D. Kushner (Ottawa, University, Ottawa, Canada). In: Comets for primitive replication, the phylogentic sequence of metabolic

97 A82-20902

pathways in the Precambrian, and the evolution of Rhodospirillaceae Co., 1981, p. 33-42. 29 refs. NSF Grant No. AST-79-14789; Grant and mitochondria. A.L.W. No. NsG-7301. The organic molecules sublimating from the cometary nucleus either represent the 'frost' of interstellar molecules that condensed A82-20902 Interstellar molecules and the origin of life. R. onto those interstellar grains that have later accreted into comets, or D. Brown (Monash University, Clayton, Victoria, Australia). In: they represent the 'snows' that condensed onto silicate grains during Origin of life; Proceedings of the Third ISSOL Meeting and Sixth the cooling phase of the presolar nebula. Even if one does not accept ICOL Meeting. Jerusalem, Israel, June 22-27, 1980. the speculations of Hoyle and Wickramashinghe (1977), the fact that Dordrecht, D. Reidel Publishing Co., 1981, p. 1-9. 11 prebiotic chemistry could have been brought from the interstellar refs. space or from the solar nebula to the Earth by comets is an intriguing The hypothesis that life on earth arose not as a consequence of possibility that cannot be ruled out at this stage. (Author) in situ chemical evolution but instead arrived at earth from interstellar space is considered. Problems with the orthodox view related to the probable nature of the original earth atmosphere and A82-20907 Liquid water on a planet over cosmic periods. the accumulation of prebiotic molecules in the presence of solar UV M. D. Papagiannis (Boston University, Boston, MA). In: Origin of radiation are first noted. The complex organic molecules detected in life; Proceedings of the Third ISSOL Meeting and Sixth ICOL dark nebulae, from which stars and planetary systems are believed to Meeting, Jerusalem, Israel, June 22-27, 1980. be formed, are listed, and studies of the spectroscopic properties of Dordrecht. D. Reidel Publishing Co., 1981, p. 43-50. 13 refs. gaseous forms of urea and glycine are noted. The collapse and From the equation that determines the average temperature of a heating of a dark cloud are considered, and evidence from carbona- planet, it is seen that even small changes in the distance, albedo and ceous chondrites that some cloud material is never heated above 100 greenhouse effect of the planet, if not properly compensated, can C during star formation is noted. Hypotheses for the transport of eliminate liquid water from the surface of the planet through either complex organic material to earth in meteorites and the transport of runaway glaciation or a runaway greenhouse effect. Since active life life evolved in cometary nuclei to earth in micrometeorites are also requires the presence of liquid water, and since its evolution to considered. A. L.W. higher intelligence seems to require billions of years, it follows that the ability of planets to maintain liquid water over cosmic periods is A82-20904 On the origin of organic molecules in inter- probably the critical factor that determines the abundance of stellar space and some of its consequences. K. L. V. Johansson advanced civilizations in the cosmos. (Author) (Astronomiska Observatoriet. Uppsala, Sweden). In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, A82-20908 * Organic analysis of the Antarctic carbonaceous Jerusalem, Israel, June 22-27, 1980. Dordrecht, chondrites. R. K. Kotra, A. Shimoyama, C. Ponnamperuma (Mary- D. Reidel Publishing Co., 1981, p. 1%25. land, University, College Park, MD), P. E. Hare (Carnegie Institution Possible sources for the complex organic molecules observed in of Washington, Washington, DC), and K. Yanai (National Institute of interstellar space are examined, and consequences of the likley Polar Research, Tokyo, Japan). In: Origin of life; Proceedings of the sources for the origin of life on earth are discussed. Calculations are Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, presented which show that the amount of molecules that may have June 22-27, 1980. Dordrecht, D. Reidel Pub- escaped from lifebearing planets such as earth is insufficient to lishing Co., 1981, p. 51-57. 14 refs. NSF Grants No. DPP-77-06993; account for the observed quantities of organic molecules in inter- No. DPP-79-00991; Grant No. NGR-21-002-317. stellar space. Rather, the molecules must have formed in interstellar Thus far, organic analysis of carbonaceous chondrites has proven clouds, either free in space or on the surfaces of grains. Such the only fruitful means of examining complex organic matter ot interstellar clouds may have been a source of organic compounds in extraterrestrial origin. The present paper presents the results of the formation of the solar system, or may have deposited a organic analysis of two Antarctic meteorites, Allan Hills (77306) and substantial amount of organic molecules on earth as the solar system Yamato (74662), which may be considered free from terrestrial passed through a cloud. The subsequent chemical evolution of this contamination. Ion-exchange chromatography, gas chromatography material into biological molecules may be investigated by Urey-Miller and mass spectrometery of meteorite samples reveal the presence in type experiments with more complex starting mixtures than usual. Yamato of 15 and in Allan Hills of 20 protein and nonprotein amino A.L.W. acids, the most abundant of which are glycine and alanine. Abundances of the D and L enantiomers of each amino acid are also A82-20905 * Comets and the origin of life. W. M. Irvine found to be nearly equal. Data thus indicate an abiotic extra- (Onsala Space Observatory, Onsala, Sweden), S. B. Leschine, and F. terrestrial origin for the matter, and confirm a lack of terrestrial P. Schloerb (Massachusetts, University, Amherst, MA). In: Origin of contamination. A. L.W. life; Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. A82-20909 Nitrogen compounds in carbonaceous meteor- Dordrecht, D. Reidel Publishing Co., 1981, p. 27-32. 38 refs. Grant ites - A reassessment. P. G. Stoks and A. W. Schwartz (Nijmegen, No. NGL-22-010-023. Katholieke Universiteit,-Nijmegen, Netherlands). In: Origin of life; The possible role of comets as sites for chemical and/or Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, biological evolution is considered from both the positive and the Jerusalem, Israel, June 22-27, 1980. Dordrecht, negative viewpoints. On the negative side, it is pointed out that direct D. Reidel Publishing Co., 1981, p. 59-64. 28 refs.. evidence for the chemical composition and size of cometary nuclei is A reinvestigation of the presence of N-heterocyclic compounds lacking and the thermal history of comets is unknown, so that the in the Murray, Murchison and Orgueil carbonaceous meteorites has length of time that liquid water could have been available ranges been undertaken. The positive identification of the pyrimidine uracil from zero to over a billion years. On the positive side, there remains and the purines adenine, guanine, xanthine and hypoxanthine is the possibility that there may have been comets which retained reported. The s-triazines melamine, ammeline, ammelide and cyan- liquid water in their interior for a sufficient time and that have more uric acid could not be detected in any meteorite, above a detection complex molecules than the amino acids and nucleic acid bases limit of 50 ppb. These results, together with laboratory data on the found in carbonaceous chondrities, and that the cometary environ- formation of s-triazines, are discussed in relation to proposed ment may have been more favorable to the origin of life than the mechanisms of formation of organic compounds in carbonaceous terrestrial. It has also been demonstrated that cometary material falls meteorites. (Author) to earth at a significant rate. Problems in understanding the course of chemical evolution on earth may thus have a solution in cometary A82-20910 Abiotic organic synthesis in space. M. R. Bloch processes. A. L.W. (Max-Planck-lnstitut fiir Kernphysik, Heidelberg, West Germany) and H. L. Wirth (Negev, University, Beersheba, Israel). In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, A82-20906 * Nature and origin of organic molecules in Jerusalem, Israel, June 22-27, 1980. Dordrecht, comets. A. H. Delsemme. In: Origin of life; Proceedings of the Third D. Reidel Publishing Co., 1981, p. 65-71. 14 refs. ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June An experimental model for the formation of iron meteorites in 22-27, 1980. Dordrecht, D. Reidel Publishing space is presented which may also account for the presence of

98 A82-20919 organic substances in comets and meteorites. The model consists of A82-20915 * Possible role of phosphine in chemical evolu- passing iron carbonyl and nickel carbonyl gas mixtures with H2S at tion. F. Raulin (Paris XII, Universite, Creteil, Val-de-Marne, France) 180 C between the poles of a permanent magnet. Strings of and C. Ponnamperuma (Maryland, University, College Park, MD). In: iron-nickel globules are formed which are similar in structure and Origin of life; Proceedings of the Third ISSOL Meeting and Sixth chemical composition to the kamacite, taenite, troilite and pent- ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. landite phases of meteorites. The carbonyl groups may then react in Dordrecht. D. Reidel Publishing Co., 1981, p. a Fischer-Tropsch-type reaction to form graphite and hydrocarbons, 107-114. 18 refs. Research supported by the Centre National de la as observed in commercial processes. It is suggested that temperature Recherche Scientifique and NSF; Grant No. NGR-21-002-317. gradients produced as comets near the sun may lead to the collection Experiments simulating the formation of organic molecules in of metal carbonyls in the cometary interior, and that the resultant model reducing atmospheres including phosphine show that a variety synthesis in a magnetic field may account for the optical activity of of organic molecules can be synthesized. From the experiments using organic compounds. A.L.W. UV light as an energy source, it appears that the presence of phosphine drastically increases the yield of photolysis of methane A82-20911 Formation of prebiotic precursors from model and, thus, the yield of the formation of organic matter. The presence reducing atmospheres - Role of hydrogen escape. D. Mourey, F. of phosphine enhances the formation of organophosphorous com- Raulin, and G. Toupance (Paris XII, Universite, Creteil, Val-de- pounds, such as methyl and dimethylphosphine. (Author) Marne, France). In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, A82-20916* Clays as prebiotic photocatalysts. L. M. 1980. Dordrecht, D. Reidel Publishing Co., Coyne, J. Lawless (NASA, Ames Research Center, Moffett Field, 1981, p. 73-82. 12 refs. Research supported by the Centre National CA), N. Lahav (Jerusalem, Hebrew University, Rehovot, Israel), S. d'Etudes Spatiales; Centre National de la Recherche Scientifique Sutton (Washington University, St. Louis, MO), and M. Sweeney Grant No. 3721. (Santa Clara, University, Santa Clara, CA). In: Origin of life; The influence of the atmospheric escape of hydrogen on the Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, chemical evolution of a reducing atmosphere and on the synthesis of Jerusalem, Israel, June 22-27, 1980. Dordrecht, organic compounds within it is investigated. Experiments were D. Reidel Publishing Co., 1981, p. 115-124. 24 refs. performed in the absence of liquid water in a discharge chamber Clay minerals catalyze peptide bond formation in fluctuating containing 50 torr CH3 and 100 torr gaseous H20 with palladium environments. A number of plausible mechanisms have been pro- membranes to permit the escape of the H2 formed. In experiments posed and tested. The possibility that clays may actually be performed without H2 escape, H2 rapidly becomes the most energizing the reaction by means of electronic excitation, creating abundant product, and a steady-state CO/C02 concentration ratio of mobile or trapped holes and electrons in the lattice, is explored. It about 7 is reached by the end of the experiment. In contrast, has been discovered that clays emit light upon dehydration. The hydrogen escape during the course of the reaction causes a more correlation between dehydration-induced, or thermoluminescent, rapid decline in CH4 concentration, decreases in CO and H20 processes and the yield of glycine oligomers after treatments known concentration, and a steady state characterized by greater levels of to affect the luminescent yields is being tested, in an effort to C02 than CO. The hydrocarbons formed are also observed to be understand the catalytic mechanism. (Author) more rapidly destroyed in the oxidizing atmosphere resulting from hydrogen escape, although hydrogen escape has no effect on the A82-20917 * Clay-mediated reactions of HCN oligomers - synthesis of oxygen-containing organics. A.L.W. The effect of the oxidation state of the clay. J. P. Ferris, K. W. Alwis, E. H. Edelson, N. Mount, and W. J. Hagan, Jr. (Rensselaer A82-20912 Organic chemical evolution of reducing model Polytechnic Institute, Troy, NY). In: Origin of life; Proceedings of of the atmosphere of the primitive earth - Role of UV light and the Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, electric discharges. A. Bossard, F. Raulin, D. Mourey, and G. June 22-27, 1980. Dordrecht, D. Reidel Publish- Toupance (Paris XII, Universite, Creteil, Val-de-Marne, France). In: ing Co., 1981, p. 125-128. 12 refs. NSF Grant No. CHE-76-11000; Origin of life; Proceedings of the Third ISSOL Meeting and Sixth Grant No. NGR-33-018-148. Montmorillonite clays which contain Fe(lll) inhibit the oligo- ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. merization of aqueous solutions of HCN. The inhibitory effect is due Dordrecht, D. Reidel Publishing Co., 1981, p. 83-92. to the rapid oxidation of diaminomaleonitrile, a key intermediate in 24 refs. Research supported by the Centre National d'Etudes Spatiales. HCN oligomerization, by the Fe(lll) incorporated into the aluminc- silicate lattice of the clay. The Fe(lll) oxidizes diaminomaleonitrile A82-20913 Far UV photolysis of methane-water gaseous to diiminosuccinonitrile, a compound which is rapidly hydrolyzed to mixtures and the prebiotic synthesis of aldehydes. A. Bossard and G.. HCN and oxalic acid derivatives. Diaminomaleonitrile is not oxidized Toupance (Paris XII, Universite, Creteil, Val-de-Marne, France). In: when Fe(lll) in the montmorillonite is reduced with hydrazine. The Origin of life; Proceedings of the Third ISSOL Meeting and Sixth oxidation state of the clay is an important variable in experiments ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. designed to simulate clay catalysis on the primitive earth. (Author) Dordrecht, D. Reidel Publishing Co., 1981, p. 93-100. 18 refs. Research supported by the Centre National d'Etudes A82-20918 Chemical evolution and plate tectonics. D. E. Spatiales. Ingmanson (California, University, La Jolla, CA) and M. J. Dowler (San Diego State University, San Diego, CA). In: Origin of life; A82-20914 * Photolysis of CH4-IMH3 mixtures and PH3 as Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, models for the photochemical transformations on the primitive earth Jerusalem, Israel, June 22-27, 1980. Dordrecht, and Jupiter. J. P. Ferris, J. Y. Morimoto, and R. Benson (Rensselaer D. Reidel Publishing Co., 1981, p. 129-134. 25 refs. Polytechnic Institute, Troy, NY). In: Origin of life; Proceedings of Laboratory analysis of Red Sea Atlantis II Deep brine solutions the Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, revealed a significant thiocyanate concentration (0.000024 M). June 22-27, 1980. Dordrecht, D. Reidel Publish- Amino acid analysis revealed large quantities of glycine (about 1 ing Co., 1981, p. 101-105. 13 refs. Grant No. IMGR-33-018-148. micromole per liter), and no other dissolved free amino acids. This Methane, ammonia and phosphine are some of the possible brine and the underlying sediment constitute a reducing, acidic, constituents of the atmospheres of the Jovian planets and -their clay-rich, anhydrous-to-hydrous gradient system that can vary in satellites. Photolysis of NH3 in the presence of CH4 at 185 nm in the temperature from 1100 C underlying magma to 63 C water. Since temperature range of 25 C to -100 C results in the decomposition of these conditions occur along a sea floor spreading zone, there may be CH4. The reaction is inhibited by added H2 or SF6. These findings an important link between the origin and evolution of the earth's are consistent with the reaction of hot hydrogen atoms with CH4 to crust and chemical evolution. (Author) give the CH3 radical. P2H4 is the initial product formed by the photolysis of PH3 at 206 nm. Kinetic studies established that it is the intermediate in the formation of P4 from PH3. The potential A82-20919 The Strecker synthesis in the primitive ocean. significance of these reactions to the atmospheric photochemistry of S. L. Miller and J. E. Van Trump (California, University, La Jolla, the Jovian planets and moons is discussed. (Author) CA). In: Origin of life; Proceedings of the Third ISSOL Meeting and

99 A82-20920

Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. and pyrimidine. The organic phosphate formed from 2- Dordrecht, D. Reidel Publishing Co., 1981, p. methylimidazole has been shown to be an alkali-labile phosphoric 135-141. 6 refs. acid ester of a 4,5-dihydroxyimidazoline. Results emphasize the Most prebiotic amino acid syntheses proceed through the amino importance of reactions, such as those involving coupling between nitrile (Strecker synthesis). The equilibrium constants for the energy and group transfer, in the first steps of chemical organization formation of glycine nitrile and alanine nitrile have measured as well in open systems capable of generalized Darwinian evolution. A.L.W. as the kinetics of their hydrolysis to the amides and amino acids. From the data the yields of amino and hydroxy acids can be A82-20923 Abiotic synthesis of phosphoric esters of calculated as a function of pH, temperature and ammonia concentra- monosaccharides according to the 'cold model'. C. I. Simionescu, S. tion. It can also be shown that amino acids can be synthesized at Dumitriu and A. Constantinescu (lasi, Institutul Politehnic, lasi, high dilutions in the primitive ocean. (Author) Rumania). In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. Dordrecht, D. Reidel Publishing Co., 1981, p. A82-20920 * Photoassisted carbon dioxide reduction and formation of two- and three-carbon compounds. M. Halmann, B. 165-172. 13 refs. Aurian-Blajeni (Weizmann Institute of Science, Rehovot, Israel), and A82-20924 Synthesis and degradation of amino acids by S. Bloch (Paris XII, Universite, Creteil, Val-de-Marne, France). In: contact glow discharge electrolysis, a possible route for prebiotic Origin of life; Proceedings of the Third ISSOL Meeting and Sixth formation of bio-organic compounds. K. Harada, J.-l. Terasawa, and ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. H. Gunji (Tsukuba, University, Sakura, Ibaraki, Japan). In: Origin of Dordrecht, D. Reidel Publishing Co., 1981, p. life; Proceedings of the Third ISSOL Meeting and Sixth ICOL 143-150. 25 refs. Research supported by the U.S.-lsrael Binational Meeting, Jerusalem, Israel, June 22-27, 1980. Science Foundation and NASA. Dordrecht, D. Reidel Publishing Co., 1981, p. 173-180. 13 refs. The photoassisted reduction of aqueous carbon dioxide in the presence of naturally occurring minerals is investigated as a possible abiotic precursor of photosynthesis. Aqueous carbon dioxide saturat- A82-20925 Genesis of amino acids in the primeval sea - ed suspensions or surfaces of the minerals nontronite, bentonite, Formation of amino acids from sugars and ammonia in a modified anatase, wolframite, molybdenite, minium, cinnabar and hematite sea medium. H. Yanagawa, Y. Kobayashi, and F. Egami (Mitsubishi- were irradiated with high-pressure mercury lamps or sunlight. Kasei Institute of Life Sciences, Tokyo, Japan). In: Origin of life; Chemical analyses reveal the production of formic acid, formal- Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, dehyde, methanol and methane, and the two and three-carbon Jerusalem, Israel, June 22-27, 1980. Dordrecht, compounds glyoxal (CHOCHO) and malonaldehyde (CH2(CHO)2). D. Reidel Publishing Co., 1981, p. 181-187. 11 refs. It is suggested that such photosynthetic reactions with visible light in the presence of semiconducting minerals may provide models for A82-20926 Porphyrin-like compounds genesis under simu- prebiological carbon and nitrogen fixation in both oxidized and lated abiotic conditions. C. I. Simionescu, B. C. Simionescu, M. reduced atmospheres. A.L.W. Leanca, C. Ananiescu, and R. Mora (lasi, Institutul Politehnic, lasi, Rumania). In: Origin of life; Proceedings of the Third ISSOL Meeting A82-20921 Melanoidin polymers as possible oxygen sinks and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. in the pre-biotic oceans. A. Serban and A. Nissenbaum (Weizmann Dordrecht, D. Reidel Publishing Co., 1981, p. Institute of Science, Rehovot, Israel). In: Origin of life; Proceedings 189-196. 16 refs. of the Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Investigations into the synthesis of porphyrins, carried out Israel, June 22-27, 1980. Dordrecht, D. Reidel according to 'the cold theory' of the appearance and evolution of the Publishing Co., 1981, p. 151-156. 8 refs. first living forms, showed that porphyrin-like pigments are formed in An environment in which oxygen is lacking, or at least depleted, abiotic simulated conditions. Parallel studies on the classical organic is generally believed to be a prerequisite for abiotic organic synthesis. synthesis of porphyrins indicated that pyrrole and formaldehyde The present paper proposes melanoidin scavenging as an alternative were involved in their abiogenesis. The ready formation of these to ferrous ion reactions as a sink for oxygen in the prebiotic- compounds • and especially that of their metallic chelates - in abiotic atmosphere. Results are presented of experiments in which melano- conditions is significant, suggesting the possibility of their appear- idins, formed by the Maillard reaction between carbohydrates and ance and intervention during the early stage of chemical evolution. amino acids, are allowed to react with molecular oxygen. In all (Author) glucose-amino acid mixtures investigated, oxygen concentration in the gas phase above the reacting mixture is found to decrease as the A82-20927 The role of' analytical procedures in the reaction proceeds, with the oxygen consumption rate dependent on formation of biochemicals from experiments simulating the chemical the nature of the amino acid as well as the temperature. Variations in evolution of primeval earth. F. Stoetzel, A. Shimoyama, C. Pon- the oxygen consumption rate also indicate the presence of several namperuma, and R. Buvet (Paris XII, Universite, Creteil, Val-de- intermediates in melanoidin-polymer synthesis. It is concluded that Marne, France; Maryland, University, College Park, MD). In: Origin the prebiotic formation of amine and carbohydrate monomers of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL should lead to the generation of melanoidin-like polymers which, as Meeting, Jerusalem, Israel, June 22-27, 1980. they condense, would remove oxygen into ocean sediments. A.L.W. Dordrecht, D. Reidel Publishing Co., 1981, p. 197^199.

A82-20922 Formation of energy rich phosphate in Fenton's reaction. 0. Saygin and P. Decker (Hannover, Tierarztliche A82-20928 * Reduction of thionucleosides - A prebiotic Hochschule, Hanover, West Germany). In: Origin of life; Proceedings pathway to deoxyribonucleosides. A. D. Patel, W. H. Schrier, M. A. of the Third ISSOL Meeting and'Sixth ICOL Meeting, Jerusalem, Hrncir, and J. J. Nagyvary (Texas A & M University, College Station, Israel, June 22-27, 1980. Dordrecht, D. Reidel TX). In: Origin of life; Proceedings of the Third ISSOL Meeting and Publishing Co., 1981, p. 157-164. 28 refs. Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. The oxidation of various substrates by a-modified Fenton's Dordrecht, D. Reidel Publishing Co., 1981, p. reagent is examined as a possible source of radical intermediates 201-207. 14 refs. NASA-supported research. capable of incorporating phosphate or acylate ions into energy-rich A mechanism is proposed for the prebiotic synthesis of compounds, under prebiotic conditions. Experiments were per- deoxyribonucleotides and possible nucleic acid analogs from ribo- formed in systems of Na2HPO4.2H20, FeSO4.7H2O, ascorbic acid, nucleotides by a pathway involving 2'-thio-2'-deoxyribonucleosides. amd EDTA at 0 C with H202 or O2 added as the oxidant and The mechanism is supported by laboratory experiments in which substrates including imidazoles, purines, pyrimidines, cyanamide, and 2'-thio-2'-deoxycytidine was synthesized from anhydro arabinosyl formamide. Yields of up to 32% inorganic phosphate transformed cytosine in dithiophosphate and CS2. The subsequent reduction of into organic form are obtained with 2-methylimidazole as the the thio-analogs has been achieved with ferrous ion, and photo- substrate, with positive results also found in reactions with imi- chemically. It is noted that the proposed pathway for prebiotic dazole, 1-methylimidazole, 4-hydroxymethylimidazole, histamine. deoxyribonucleotide synthesis is in harmony with the Principle of

100 A82-20937

Continuity, as both the proposed and present pathways rely on the exchange resin. S. Morimoto, K. Kawashiro, H. Yoshida, and K. reduction of a 2' functional group. A.L.W. Sugiura (Tokushima University, Tokushima, Japan). In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL A82-20929 * Factors influencing the rate of non-enzymatic Meeting, Jerusalem, Israel, June 22-27, 1980. activation of carboxylic and amino acids by ATP. D. W. Mullins, Jr. Dordrecht, D. Reidel Publishing Co., 1981, p. 247-254. and J. C. Lacey, Jr. (Alabama, University, Birmingham, AL). In: The separation of the products of the polymerization of Origin of life; Proceedings of the Third ISSOL Meeting and Sixth alpha-aminopropionitrile (APN) on Amberlite CG-50 cation- ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. exchange resin is discussed. The polymerization products, which Dordrecht, D. Reidel Publishing Co., 1981, p. were formed from the reaction of APN with alpha, alpha-prime- 209-215. 12 refs. Grant No. NGR-01-010-001. iminodipropionitrile at 0 C over the course of eight years, underwent The nonenzymatic formation of adenylate anhydrides of car- batch separation with Amberlite CG-50 equilibrated with water to boxylic and amino acids is discussed as a necessary step in the origin yield the acidic and neutral component, equilibrated with aqueous of the genetic code and protein biosynthesis. Results of studies are acetic acid to yield the weakly basic component, and equilibrated presented which have shown the rate of activation to depend on the with ammonia to yield the basic component. Each component was pKa of the carboxyl group, the pH of the medium, temperature, the then fractionated through a Sephadex G-10 column to separate divalent metal ion catalyst, salt concentration, and the nature of the polymer and oligomer sections. Amino acid analysis was performed amino acid. In particular, it was found that of the various amino on the gel-filtration fractions of each component, indicating the acids investigated, phenylalanine had the greatest affinity for the peptide, peptide amide and peptide nitrile nature of the acidic and adenine derivatives adenosine and ATP. Results thus indicate that neutral, weakly basic, and basic components, respectively, as well as selective affinities between amino acids and nucleotides were the presence of imino compounds in each component. A.L.W. important during prebiotic chemical evolution, and may have played a major role in the origin of protein synthesis and genetic coding. A82-20935 The cold theory of the origins of life - A.L.W. Assumptions for the theory and experimental evidence. C. I. A82-20930 HCN oligomerization - Isolation and prelim- Simionescu and F. Denes (Institute of Macromolecular Chemistry, inary characterization of a new precursor of adenine. A. B. Voet and lasi, Rumania). In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, A. W. Schwartz (Nijmegen, Katholieke Universiteit, Nijmegen, 1980. Dordrecht, D. Reidel Publishing Co., Netherlands). In: Origin of life; Proceedings of the Third ISSOL 1981, p. 255-262. 13 refs. Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, Experimental results obtained in low temperature conditions 1980. Dordrecht, D. Reidel Publishing Co., and using a cold plasma as an energy source are presented as a basis 1981, p. 217-223. 22 refs. for a cold theory of the origins of life. Reasoning that a recombination of active species does not occur in chemical thermo- A82-20931 * Cyanamide mediated syntheses of leu, ala, and dynamics, experiments were performed to find evidence that phe peptides under plausible primitive earth conditions. J. R. macromolecular precursors to living matter accumulated on ice- Hawker, Jr. and J. Oro (Houston, University, Houston, TX). In: covered surfaces. Polypeptide-like and polysaccharide-like materials Origin of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. were formed when a feed composition of NH3 was injected into an Dordrecht, D. Reidel Publishing Co., 1981, p. apparatus which modeled the early earth's environment by having ice 225-232. 20 refs. Grant No. NGR-44-005-002. at -60 deg at the bottom of a reactor and an RF electrode to create a plasma on the top. Protobiopolymers were found to form lipid-like A82-20932 * Template-directed synthesis of oligoguanylic structures which self-assembled and exhibited membrane-like struc- acids - Metal ion catalysis. P. K. Bridson, H. Fakhrai, R. Lohrmann, tures with electrical properties suggestive of reversible transducers of L. E. Orgel, and M. van Roode (Salk Institute for Biological Studies, various kinds of energies. M.S.K. San Diego, CA). In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, A82-20936 The appearance of protobiopolymers and 1980. Dordrecht. D. Reidel Publishing Co., protomembranes in accordance with the 'cold theory' of the origins 1981, p. 233-239. 7 refs. Grants No. NGR-05-067-001; No. of life. C. I. Simionescu, F. Denes, and M. Totolin (Institute of NIH-GM-13435. Macromolecular Chemistry, lasi, Rumania). In: Origin of life; The effects of Zn(2+), Pb(2+) and other metal ions on the Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, efficiency and stereo-selectivity of the template-directed oligomeriza- Jerusalem, Israel, June 22-27, 1980. Dordrecht, tion of guanosine 5'-phosphorimidazolide are investigated. Reactions D. Reidel Publishing Co., 1981, p. 263-269. .14 refs. were run in the presence of a polyC template in a 2,6-lutidine buffer, Analyses of the reaction products of an RF cold plasma and products analyzed by high-performance liquid chromatography discharge in a mixture of CH4, NH3, and H2O gases which formed on an RPC-5 column. The presence of the Pb(2+) ion is found to lead protobiopolymers are reported. Polypeptide and polysaccharide type to the formation of 2'-5' linked oligomers up to the 40-mer, while substances were formed in the presence of dominant concentrations Zn(2+) favors the formation of predominantly 3'-5' linked oligomers of NH3 and H20, while methane dominated mixtures yielded up to the 35-mer. When amounts of uracil, cytidine or adenosine lipid-like structures. Spectral analyses, chromatography, gel permea- 5'-phosphorimidazole equal to those of the guanosine derivative are tion measurements, elemental analysis, electron microscopy, SEM, included in the reaction mixture, the incorrect base is incorporated and optical microscopy were employed, and it is noted that the into the oligomer about 10% of the time with a Pb(2+) catalyst, but lipid-like materials are induced to form specific orientations to the less than 0.5% of the time with Zn(2+). The Sn(2+), Sb(3+) and fluid medium and form organized entities with protomembranes. Bi(3+) ions are also found to promote the formation of 2'-5' Double layers were found in the microspheres, which had a oligomers, although not as effectively as Pb(2+), while no metal ions membrane potential of 30 mV. Microsphere-assisted phosphorylation other than Zn(2+) promote the formation of the 3'-5' oligomers. The was investigated starting from KH2P04, and yielded a polyphos- results may be important for the understanding of the evolution of phate, which is considered significant for early bioenergetical nucleic acid replication in the absence of enzymes. A.L.W. processes. M.S.K.

A82-20933 Chemical evolution of model systems of primeval earth periphery and thermal polymerisation of aqueous A82-20937 * Terrestrial evolution of polymerization of solutions of cyanides. F. Stoetzel and R. Buvet (Paris XII, Universite, amino acids - Heat to ATP. S. W. Fox and T. Nakashima (Miami, Creteil, Val-de-Marne, France). In: Origin of life; Proceedings of the University, Coral Gables, FL). In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. Dordrecht, D. Reidel Pub- June 22-27, 1980. Dordrecht, D. Reidel Publish- lishing Co., 1981, p. 241-246. 6 refs. ing Co., 1981, p. 271-276. 10 refs. Grant No. NCR-10-007-008. Sets of amino acids containing sufficient trifunctional monomer A82-20934 The polymerization products of alpha- are thermally polymerized at temperatures such as 65 deg; the amino aminopropionitrile - The component separation using cation- acids order themselves. Various polymers have diverse catalytic

101 A82-20938 activities. The polymers aggregate, in aqueous solution, to cell-like Dordrecht, D. Reidel Publishing Co., 1981, p. structures having those activities plus emergent properties, e.g. 309-312. 5 refs. proliferatability. Polyamino acids containing sufficient lysine cata- Highly organized particles, 'marigranules', were found to be lyze conversion of free amino acids, by ATP, to small peptides and a produced from glycine and acidic, basic, and aromatic amino acids in high molecular weight fraction. The lysine-rich proteinoid is active in a modified sea medium. The marigranules had membrane-like solution, within suspensions of cell-like particles, or in other particles structures and were packed with polymers having molecular weights composed of lysine-rich proteinoid and homopolyribonucleotide. of 1,800, 6,800, 15,000, and 82,000 daltons. It is considered that Selectivities are observed. An archaic polyamino acid prelude to these marigranules represent a new type of protocell-like structures coded protein synthesis is indicated. (Author) that were present on the primitive earth. The environmental conditions for the formation of marigranules are described and A82-20938 Potentiometric titration behavior of poly- kinetic studies made on them are presented. Among amino acids, amino acids prepared by thermal polycondensation. E. Kokufuta and tryptophan was an essential amino acid for the formation of K. Harada (Tsukuba, University, Sakura, Ibaraki, Japan). In: Origin marigranules and among the metal components of modified sea of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL medium, cupric ion was absolutely necessary for the formation of Meeting, Jerusalem, Israel, June 22-27, 1980. marigranules. The form of marigranules was dependent on tempera- Dordrecht, D. Reidel Publishing Co., 1981, p. 277-284.10 refs. ture and time. The time course for the formation of these Potentiometric titrations of thermally prepared polyamino acids marigranules was oscillatory. (Author) were carried out at different ionic strengths. The intrinsic dissociation constants of carboxyl groups or amino groups in the polymers A82-20943 * Membrane lipids and the origin of life. J. Oro, were evaluated by the curves of the apparent dissociation constant G. Holzer, M. Rao (Houston, University, Houston, TX), and T. G. against the degree of dissociation and the Henderson-Hasselbalch Tornabene (Colorado State University, Fort Collins, CO). In: Origin plots. The ratio of alpha- and omega-linkages of amino acid residues of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL was also evaluated bythe analysis of the titration data. (Author) Meeting, Jerusalem, Israel, June 22-27, 1980. Dordrecht, D. Reidel Publishing Co., 1981, p. 313-322. 36 refs. A82-20939 On the polycondensation of amino acid adeny- Grant No. NGR-44-005-002. Contract No. EE-77-5-02-4478. lates on montmorillonites. F. R. Eirich (New York, Polytechnic The current state of knowledge regarding the development of Institute, Brooklyn, NY). In: Origin of life; Proceedings of the Third biological systems is briefly reviewed. At a crucial stage concerning ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June the evolution of such systems, the mechanisms leading to more 22-27, 1980. Dordrecht, D. Reidel Publishing complex structures must have evolved within the confines of a Co., 1981, p. 285-293. 9 refs. protected microenvironment, similar to those provided by the A number of studies on the mechanisms of adsorption under- contemporary cell membranes. The major components found nor- lying the catalysis mechanism show, at least, three types of mally in biomembranes are phospholipids. The structure of the adsorption, i.e. two ion exchange mechanisms on clay faces and biomembrane is examined, and attention is given to questions edges, and a general, possibly ion-pair mediated, polar adsorption. concerning the availability of the structural components which are X-ray data on dry clay-peptide sandwiches show clearly adsorption in necessary in the formation of primitive lipid membranes. Two well defined layers, while analysis of rates of polymerization, of approaches regarding the study of protomembranes are discussed. blocking experiments of clay agglomeration, and of the effects of The probability of obtaining ether lipids under prebiotic conditions polypeptide preadsorption show that the clay faces and edges are is considered, taking into account the formation of cyclic and acyclic involved in the enhancement of the polycondensation which also isoprenoids by the irradiation of isoprene with UV. G.R. requires that the clay platelet stacks can expand by interlayer adsorption during the reaction. . (Author) A82-20944 Resolution of underivatized amino acids by high pressure liquid chromatography, using chiral eluants. E. Gil-Av, A82-20940 * Polymerization of serine guanylate in the A. Tishoee, S. Weinstein (Weizmann Institute of Science, Rehovot, presence of montmorillonite. M. Paecht-Horowitz (Jerusalem, Israel), and P. E. Hare (Carnegie Institution of Washington, Washing- Hebrew University, Rehovot, Israel). In: Origin of life; Proceedings ton, DC). In: Origin of life; Proceedings of the Third ISSOL Meeting of the Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. Israel, June 22-27, 1980. Dordrecht, D. Reidel Dordrecht, D. Reidel Publishing Co., 1981, p. Publishing Co., 1981, p. 295-299. 7 refs. Grant No. 323-330. 15 refs. NGR-33-006-070. Chiral recognition through coordination to a metal ion used in Serine guanylate was prepared and its polymerization studied in conjunction with a chromatographic mode of operation is reported the presence of montmorillonite and in its absence. In water, without as a method of improving the techniques of enantiometric analysis. clay, serine guanylate polymerizes in the same way as does serine Dissolving a chiral coordination complex in an aqueous mobile phase adenylate. In the presence of montmorillonite, serine guanylate led to resolution of underivatized amino acids obtained by using as a polymerizes to a lesser extent and produces also lower degrees of support either a cation exchange resin or a reversed phase silica gel. polymerization than does serine adenylate. It is postulated that the reason for this difference in behavior might lie in the fact that Eluates are detected by post-column derivatization to fluorescent compounds. A reversed phase column was found to be more efficient guanylic acid is much more acidic than adenylic acid; hence would bind much more strongly to the edges of montmorillonite and thus, for determining the resolution factor for enantiomer emergence than by use of an exchange resin, and chiral recognition was discovered to by blocking these sites, would inhibit the catalytic activity of the clay. (Author) occur mainly in the mobile phase. Picomoles of eluate were observable, but only with primary, rather than secondary amino groups. M.S.K. A82-20941 Quantum mechanical conformations! analysis of aminoacyladenylates - Implication in the origin of life. H. Broch, A82-20945 Stereoselective interactions of small biological D. Cabrol, and D. Vasilescu (Nice, Universite, Nice, France). In: molecules. Y. H. Kim, A. Tishbee, and E. Gil-Av (Weizmann Institute Origin of life; Proceedings of the Third ISSOL Meeting and Sixth of Science, Rehovot, Israel). In: Origin of life; Proceedings of the ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, Dordrecht, D. Reidel Publishing Co., 1981, p. June 22-27, 1980. Dordrecht, D. Reidel Publish- 301-308. 16 refs. Research supported by the Centre National de la ing Co., 1981, p. 331-336. 19 refs. Recherche Scientifique and Direction des Recherches, Etudes et Work being done on charge transfer complexation and chiral Techniques. recognition is surveyed, with attention given to its extension to stationary phases consisting of relatively small biological molecules. A82-20942 Environmental conditions for the formation of The experiments reported deal with the resolution of synthetic marigranules and kinetic studies on the formation. H. Yanagawa and molecules, the helicenes, not found in nature. They focus attention F. Egami (Mitsubishi-Kasei Institute of Life Sciences, Tokyo, Japan). on the discrimination of certain optical isomers by biological In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth substances through the combined effect of charge transfer complexa- ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. tion and chiral recognition through a sugar residue. These observa-

102 A82-20956 tions are thought to be of considerable interest since modern Histidyl-histidine is a remarkably effective catalyst of peptide carbohydrate chemistry puts much emphasis on the information bond formation in the reaction of glycine in a fluctuating (hot-dry, content of sugars and their functions in molecular recognition. It is cold-wet) clay environment. It has shown turnover numbers (mole- noted that, by examining, as stationary phases, a systematically cules of glycine incorporated in oligoglycines per molecule of modified series of compounds, the influence of structural factors on catalyst) as high as 18 in a single cycle and as high as 52 overall. A chiral recognition could be investigated and eventually a model for number of other dipeptides were tested, as well as monomeric the mechanism evolved. C. R. histidine, N-acetyl histidine, and imidazole, none of which showed turnover numbers greater than one. Histidyl-histidine is a model for a A82-20946 * Possible selective adsorption of enantiomers prebiotic protoenzyme, and implications for the development of a by Na-montmorillonite. E. Friebele, A. Shimoyama, and C. Pon- simple translation mechanism are discussed. (Author) namperuma (Maryland, University, College Park, MD). In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth ICOL A82-20953 A mathematical method for the enumeration Meeting, Jerusalem, Israel, June 22-27, 1980. of doublet codes. G. Cullmann (Institut Georges Gamow, Clermont- Dordrecht, D. Reidel Publishing Co., 1981, p. 337-346. 13 refs. NSF Ferrand, France). In: Origin of life; Proceedings of the Third ISSOL Grant No. EAR-77-00013; Grant No. NGR-21-002-317. Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, Racemic amino acids including (D,L) alpha-alamine, (D,U 1980. Dordrecht, D. Reidel Publishing Co., alpha-aminobutyric acid, (D,L) valine, and (D,L) norvaline were 1981, p. 405-413. 7 refs. incubated with Na-montmorillonite at 100% CEC at three hydrogen A single nonsense mutation is a mutation of a codon outside its ion concentrations, and amino acid adsorption was determined by code, wherein only one base changes under the mutation. The best ion exchange chromatography. Enantiomers were analyzed by gas code is one which has the minimum number of single nonsense chromatography. Differences in the quantities of D and L enan- mutations and, therefore, a definite Hamming's distance. The tiomers in any of the fractions was no larger than a few percent. Hamming's distance (Hamming, 1950) represents the maximum Although a large difference in the adsorption of the amino acid number of codons which differ in one base only. All the codes for a enantiomers was not observed, the analysis may indicate a small given Hamming's distance can be listed by a process known as preferential adsorption (0.5-2%) of L-amino acids by Na- combinatory analysis. A simple example of theoretical doublet codes montmorillonite. V.L. with four bases is presented; it is maintained, however, that the method can be extended to any length, and in particular, to triplet A82-20949 Asymmetrical radical formation in beta- codes. J.F. irradiated D- and L-alanines. M. Akaboshi, M. Noda, K. Kawai, H. Maki, aid K. Kawamoto (Kyoto University, Osaka, Japan). In: A82-20954 * Evolving nucleotide binding surfaces. T. Origin of life; Proceedings of the Third ISSOL Meeting and Sixth Kieber-Emmons and R. Rein (Roswell Park Memorial Institute, ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. Buffalo, NY). In: Origin of life; Proceedings of the Third ISSOL Dordrecht. D. Reidel Publishing Co., 1981, P. Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 373-378. 5 refs. 1980. Dordrecht, D. Reidel Publishing Co., It was demonstrated that the relative radical concentration was 1981, p. 415-422. 14 refs. Grant No. NsG-7305. distinguishably higher in D-alanine than in L-alanine when irradiation An analysis is presented of the stability and nature of binding of was carried out by using a yttrium-90 beta-ray source. On the other a nucleotide to several known dehydrogenases. The employed hand, when irradiation was carried out by using non-polarized approach includes calculation of hydrophobic stabilization of the beta-rays derived from a Van de Graaf generator, no such difference binding motif and its intermolecular interaction with the ligand. The was observed in the radical formation of both alanines. The results evolutionary changes of the binding motif are studied by calculating suggested that some process being involved in the parity non- the Euclidean deviation of the respective dehydrogenases. Attention conservation in a beta-decay must play an important role in the is given to the possible structural elements involved in the origin of observed phenomenon. (Author) nucleotide recognition by non-coded primordial polypeptides. (Author) A82-20951 Competition, coexistence and irreversibility in models of early molecular evolution. C. Blomberg, G. von Heijne, A82-20955 Origin and evolution of the genetic code. M. and 0. Leimar (Kungl. Tekniska Hogskolan, Stockholm, Sweden). Shimizu (Tokyo, University, Tokyo, Japan). In: Origin of life; In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. Jerusalem, Israel, June 22-27, 1980. Dordrecht, Dordrecht, D. Reidel Publishing Co., 1981, p. D. Reidel Publishing Co., 1981, p. 423-430. 23 refs. 385-392. 5 refs. A hole on a complex of anticodon and discriminator base on a Mathematical models of prebiotic systems are considered for tRNA has a key hole - key relation to the side chain of the particular applications to the cases of irreversibility and coexistence corresponding amino acid. The protein synthesis system might have in early molecular evolution. It is found that irreversibility in evolved so that it could have continuously utilized the above biologic systems is not well defined, and several models are stereochemical discrimination scheme. 'Half tRNA' might have been considered which are limited by monomer availability. Attention is the form of the primitive tRNA and the primitive ribosome might paid to a linear model, where fitness results in the survival of a have had a hairpin structure with two CAAGR on both sides of it. specific polymer over another through more successful use of (Author) available monomers, to a model of hypercycle growth, where evolution must occur within a cycle by species which require fewer monomers. Consideration is also given to a dimerization model, A82-20956 The origin and evolution of the genetic code. where different species will coexist while monomer concentrations A. Figureau (Lyon I, Universite, Villeurbanne, Rhone, France) and will decrease, to a model for the incorporation of monomers by one J.-M. Labouygues (Institut Georges Gamow, Clermont-Ferrand, species to form another species, to coexistent hypercycle systems in France). In: Origin of life; Proceedings of the Third ISSOL Meeting niches beside one another, and to a steady-state existence between and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. two species unable to eliminate one another, implying coexistence in Dordrecht, D. Reidel Publishing Co., 1981, p. prebiotic conditions. M.S.K. 431-437. 13 refs. A quantitative model is examined, which suggests that the A82-20952 * Histidyl-histidine catalysis of glycine conden- present genetic code appeared under the influence of mutations and sation in fluctuating clay environments. D. H. White and J. C. evolved by optimizing its resistance to their effects. The number of Erickson (Santa Clara, University, Santa Clara, CA). In: Origin of sense codons grew progressively, whereas the number of terminators life; Proceedings of the Third ISSOL Meeting and Sixth ICOL decreased. The most important constraint is due to the selection Meeting, Jerusalem, Israel, June 22-27, 1980. against the appearance of nonsense codons. The competition Dordrecht, D. Reidel Publishing Co., 1981, p. 393-397. Research between ancestor codes favors those which best resist mutational supported by the Research Corp.; Grants No. NCA2-OR-685-708; effects leading to nonsense. The structure of the selected systems No. NCA2-OR-685-806. converges towards that of the present genetic code. (Author)

103 A82-20957

A82-20957 Evolutionary processes of the genetic code. T. ing Co., 1981, p. 473-479. 21 refs. NSF Grants No. DPP-77-06993, Noguchi (Tokyo College of Economics, Kokubunji, Japan). In: No. DPP-79-00991. Origin of life; Proceedings of the Third ISSOL Meeting and Sixth The Isua supracrustals of western Greenland are the oldest ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. terrestrial rocks known, dated at greater than 3,750 m.y. Metamor- Dordrecht, D. Reidel Publishing Co., 1981, p. phosed to lower amphibolite facies, they still can provide indications 439-446. 7 refs. of their original environment of deposition. Graphite is widely Evolution of the genetic code is analyzed in terms of codon- dispersed throughout the meta-sediments, particularly within the reading ability and amino-acid-recognizing ability. Three basic rules ironstones. Most of the graphite is very well ordered. However, are formulated in relation to the codon-reading ability of tRNAs several samples show a marked disorder of crystallinity. These which make it possible to classify the evolution of this ability into samples, when pyrolyzed at high temperatures, liberate organic seven stages according to the degree of perceptivity of codon- fragments of low molecular weight (m/e less than 200). The anticodon interaction. Evolutionary trees are presented for tRNAs fragments suggest that at least some of the Isua graphite is derived which show how tRNAs are related to one another. V. L. from condensation of kerogen. Carbon isotope data has been interpreted as indication of photosynthetic fractionation. Whether A82-20958 * Summary of evidence for an anticodonic basis the original organics, which are now seen as graphite, were for the origin of the genetic code. J. C. Lacey, Jr. and D. W. Mullins, biologically produced has not yet been unequivocally established. Jr. (Alabama, University, Birmingham, AL). In: Origin of life; The pyrolyzed organics detected within the meta-sediments may well Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, be the oldest molecular fossils yet found on the earth. (Author) Jerusalem, Israel, June 22-27, 1980. Dordrecht, D. Reidel Publishing Co., 1981, p. 447-456. 27 refs. Grant No. A82-20962 Secondary structures of polypeptides as evolu- NGR-01-010-001. tionary growing points. H. Baltscheffsky (Stockholm, Universitet, This article summarizes data supporting the hypothesis that the Stockholm, Sweden). In: Origin of life; Proceedings of tne Third genetic code origin vJSs based on relationships (probably affinities) ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June between amino acids and their anticodon nucleotides. Selective 22-27, 1980. Dordrecht, D. Reidel Publishing activation seems to follow from selective affinity and consequently, Co., 1981, p. 481-486. 9 refs. Statens Naturvetenskapliga Forsknings- incorporation of amino acids into peptides can also be selective. It is rad Grant No. 2292-100. suggested that these selectivities in affinity and activation, coupled The formation of beta-pleated sheet structures in experiments with the base pairing specificities, allowed the origin of the code and on Clostridia-type ferredoxin apoproteins has revealed secondary the process of translation. (Author) structures which may serve to orient appropriate cysteine sulfur residues to bind 2 Fe atoms in two 4(Fe + S) cubes. The A82-20959 Primitive transfer RNA and origin of Dar- beta-structures then disappear, yielding a hydrogen bond change winian system. M. Ishigami (Jichi Medical School, Minamikawachi, which holds significance in the protein function. Three-dimensional Tochigi, Japan) and M. Kinjo (Utsunomiya University, Utsunomiya, structures are formed by concerted hydrogen bond formation, some Japan). In: Origin of life; Proceedings of the Third ISSOL Meeting in which reversible, functionally useful changes are regarded as and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. evolutionary growing points that are a basis for more complex Dordrecht, D. Reidel Publishing Co., 1981, p. three-dimensional patterns found in present-day proteins. M.S.K. 457-464. 22 refs. The effect of polynucleotide and polypeptide on the formation A82-20963 Search for primitive replicative properties on of polypeptide is tested in order to support the theory that the early polypeptides. A. Brack and G. Spach (CNRS, Centre de protein synthesis mechanism originated in the stepwise evolution of Biophysique Moleculaire, Orleans, France). In: Origin of life; polynucleotides, which not only activate amino acids, but evolve to Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, produce better polypeptides for probionts as well (Ishigami et al., Jerusalem, Israel, June 22-27, 1980. Dordrecht, 1977). The basic protein, histone, is found to promote the reaction D. Reidel Publishing Co., 1981, p. 487-493. 9 refs. of polypeptide formation from aminoacyl adenylate. The relation- The sequences of polypeptide chains which are built up with ship between the origin and development of the genetic code and the alternating hydrophilic-hydrophobic residues concentrate themselves increase of the invariable site in protein in the course of molecular in the beta-pleated sheet conformation when dissolved in salted evolution is discussed. Finally, an analogy is drawn between the water. The sheets are more stable than the alpha-helix and are shown learning system and Darwinian evolution. J. F. to constitute a pathway to the enrichment in one enantiomer. They are considered as a single system with potential template activity. A82-20960 Evolution of the terrestrial atmosphere and its (Author) fossils in biosystems. M. Shimizu (Tokyo, University, Tokyo, Japan). In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth A82-20964 Emergence of flavin catalysis - An approach ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. based on the concept of bioorganic evolution. C. M. Visser Dordrecht, D. Reidel Publishing Co., 1981, p. (Groningen, Rijksuniversiteit, Groningen, Netherlands). In: Origin of 465-471. 18 refs. life; Proceedings of the Third ISSOL Meeting and Sixth ICOL Various fossil vestiges of C3O2 and HCHO polymers can be Meeting, Jerusalem, Israel, June 22-27, 1980. found in the living biosystem, and are thought to have resulted from Dordrecht, D. Reidel Publishing Co., 1981, p. 495-504. 37 refs. the presence of CO in the primitive earth atmosphere. The possible Bioorganic chemical analysis of present-day coenzyme mech- evolutional route of the genetic code is derived by combining the anisms (via chemical models) can reveal something about the stage of discussion of Eigen and Schuster (1978) for the formation of mRNA evolution of life in which those cofactors were introduced (and vice and that of Egami (1979) for the classification of amino acids and versa). Some cofactors date back to the time before the origin of the nucleic acid bases in relation to the genetic code. The codes are genetic code (RNA-like metabolism) whereas others are relatively specified by a series of 3rd-2nd-1st anticodons, and the C4N holes recent. Flavin prosthetic groups are anomalous however, in that they for the terminators are both small. It is found that fossil vestiges of have pre-genetic code structures but a great number of post-genetic C3O2 appear most clearly in the sequence serine-leucine- code functions (oxygen handling) and reaction mechanisms. The phenylalanine, while those of HCHO appear most clearly in the recent isolation of a deazaflavin cofactor from one of the Archae- sequence glycine-alanine-asparatic acid. Thus, the classified evolu- bacteria suggests a possible way out of this dilemma. The significance tional route of the genetic code provides good evidence for a of this for present-day flavoenzyme mechanisms is discussed. primitive environment, especially for a primitive atmosphere consist- (Author) ing of CO and N2. J.F.

A82-20961 Organic geochemistry of the Isua supra- A82-20965 Selective acylability of amino acids by non- crustals. C. Walters, A. Shimoyama, and C. Ponnamperuma (Mary- enzymic model reactions of biochemical transacylations. D. Brice, L. land, University, College Park, MD). In: Origin of life; Proceedings of Le Port, and R. Buvet (Paris XII, Universite, Creteil, Val-de-Marne, the Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, France). In: Origin of life; Proceedings of the Third ISSOL Meeting June 22-27, 1980. Dordrecht, D. Reidel Publish- and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980.

104 A82-20972

Dordrecht, D. Reidel Publishing Co., 1981, p. experimentation should look for photochemical reactions with 505-511. 18refs. autocatalytic feedback which yield an organization into cycles in a The results of experiments on the acylability of various amino steady state scenario. The oxidation of methane is mentioned for the acids by differing acyl donors to study the reactions of biochemical production of formaldehyde and the autocatalytic formation of transacylations are reported. The reactions were performed in sugars from the formaldehyde, and experiments on a nonenzymatic aqueous solutions with no enzymes and a small presence of hydroxyl photophosphorylation is described as an example of the synthesis of ions. Data on the acetylation yield obtained from acetylthiogly- energy rich intermediates. M.S.K. colate, acetvlthiocholine, and acetylphosphate show that the acetylation yields of hydrocarbonated~side chain amino acids are highest A82-20969 Ultraviolet selection pressure in the Prephaner- with acetylthioglyconates, an inversion of the acetylation yields ozoic. M. B. Rambler (Boston University, Boston, MA). In: Origin of between two thioesters occurs for amino acids which have a thiol life; Proceedings of the Third ISSOL Meeting and Sixth ICOL function, reactions from the hydroxylated side chain amino acids Meeting, Jerusalem, Israel, June 22-27, 1980. result in lower acetylation yields, and specifically high acetylation Dordrecht, D. Reidel Publishing Co., 1981, p. 537-542. 34 refs. yields are obtained in the case of cysteine and homocysteine The late appearance of metaphyta and metazoa in the fossil acetylation. Finally, it was found that, in the nonenzymatic record has often been attributed to low concentrations of ambient conditions in primitive synthesis of polypeptides, the hydrophobic oxygen and restriction of organisms to shielded habitats due to character of the amino acid chains influences the IMH2 reactivities of intense ultraviolet selection pressure (Berkner-Marshall hypothesis). the compounds with respect to their acetylation with acetyl donors. Microorganisms examined for survival as a function of UV dosage M.S.K. consistantly exhibit a capacity for radiation resistance and repair. Comparisons of lethal UV dosages of various microbes to calculations A82-20966 Experiments on transfer of organic molecular of present solar UV fluxes at 253.7 nm result in an average radiation information into crystal lattice superstructures. P. Decker and H. tolerance of 30 minutes. However, inspection of survival of protected Schweer (Hannover, Tierarztliche Hochschule, Hanover, West Ger- cells increases radiation tolerance by three orders of magnitude or 24 many). In: Origin of life; Proceedings of the Third ISSOL Meeting hours of continual radiation exposure. The observation of protective and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. mechanisms in extant microbes may be legacies from UV exposure in Dordrecht, D. Reidel Publishing Co., 1981, p. the Prephanerozoic. Radiation resistance taken together with the 513-520. 22 refs. well preserved microbiota known from the Prephanerozoic suggests Evolution in bioids, open systems which can exist in several the Berkner-Marshall hypothesis to be indefensible. (Author) steady states involves the accumulation of information relevant to its selection value, i.e. in the simplest case, the choice by mutation of A82-20970 DNA-protein complex from an extreme the most stable steady state (species). Therefore it appears problem- halophile - A histone-like protein in archaebacteria. M. Ohba and T. atical how alien information like nonstatistical structures arising in Oshima (Mitsubishi-Kasei Institute of Life Sciences, Tokyo, Japan). mineral crystallization or in interplanetary carbon compounds found In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth in meteorites could become incorporated into the terrestrial bio- ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. sphere. In contrast, an interaction of evolving biosystems with Dordrecht, D. Reidel Publishing Co., 1981, p. inorganic matter, involving temporal storage of bioinformation in 543-549. 17 refs. crystal structures, appears more compatible with the bioid concept. A model of how three independent messages can be stored in a A82-20971 * The evolution of blue-greens and the origins of three-dimensional lattice is presented. As a first experimental chloroplasts. R. M. Schwartz (National Biomedical Research Founda- approach, attempts to induce information from linear biomolecules tion, Washington, DC) and M. O. Dayhoff (Georgetown University, into a nonstatistical distribution of components of mixed crystals are Washington, DC). In: Origin of life; Proceedings of the Third ISSOL reported. (Author) Meeting and Sixth ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. Dordrecht, D. Reidel Publishing Co., A82-20967 * Phylogenetic sequence of metabolic pathways 1981, p. 551-558. 26 refs. Contract No. NASw-3317; Grants No. in Precambrian cellular life. J. Barnabas (Ahmednagar College, NIH-GM-08710; No. NIH-RR-05681. Ahmednagar, India), R. M. Schwartz (National Biomedical Research All of the available molecular data support the theory that the Foundation, Washington, DC), and M. 0. Dayhoff (Georgetown chloroplasts of eukaryote cells were originally free-living blue-greens. University, Washington, DC). In: Origin of life; Proceedings of the Of great interest is what the relationships are between contemporary Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, types of blue-greens and eukaryote chloroplasts and whether the June 22-27, 1980. Dordrecht, D. Reidel Publish- chloroplasts of the various eukaryotes are the result of one or more ing Co., 1981, p. 521-528. 55 refs. Grant No. NIH-GM-08710; than one symbiosis. By combining information from phylogenetic Contract No. NASw-3317. trees based on cytochrome c6 and 2Fe-2S ferredoxin sequences, it is A sequence of major metabolic events is presented as they may shown that the chloroplasts of a number of eukaryote algae as well as have appeared during prokaryote evolution. This is based on (1) the the protist Euglena are polyphyletic; the chloroplasts of green algae phylogenetic schema derived from sequences of bacterial ferredoxin, and the higher plants may be the result of a single symbiosis. 2Fe-2S ferredoxin, 5S ribosomal RIMA, and c-type cytochromes; (2) (Author) metabolic settings in which these macromolecules are found; and (3) A82-20972 * Evolution of the rhodospirillaceae and mito- metabolic capabilities of the prokaryotes that carry these molecules. chondria - A view based on sequence data. M. 0. Dayhoff (Author) (Georgetown University, Washington, DC) and R. M. Schwartz (National Biomedical Research Foundation, Washington, DC). In: A82-20968 Coupling to solar energy: Sensitized photo- Origin of life; Proceedings of the Third ISSOL Meeting and Sixth reactions - The primary source of self-organization. P. Decker ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. (Hannover, Tierarztliche Hochschule, Hanover, West Germany). In: Dordrecht, D. Reidel Publishing Co., 1981, p. Origin of life; Proceedings of the Third ISSOL Meeting and Sixth 559-566. 22 refs. Contract No. NASw-3317; Grant No. NIH-GM- ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. 08710. Dordrecht, D. Reidel Publishing Co., 1981, p. New sequence data from several protein families and from 5S 529-536. 31 refs. ribosomal RNA confirm and elaborate a previously proposed Life is modelled as a thermodynamically dissipative mechanism, description of the phylogenetic connections between a variety of and the chemical reactions most amenable to the formation of bacteria and the eukaryotes. Probably, the first organisms were 'bioids' which form and change from one generation to the next are nonphotosynthetic anaerobic prokaryotes, which were followed soon examined. The self-organization is assumed to occur on a planetary by photosynthetic anaerobes. From this photosynthetic stock, the surface exposed to 6000 deg light quanta, in the availability of aerobic line to Pseudomonadacae, Rhodospirillaceae, and blue-greens reactive chemicals, with nonenzymatic catalysts being present, and arose. The eukaryotes derived genetic material from the symbioses of with macromolecules able to mediate the reactivity through catalytic at least three separate bacterial lines. Ancestors of Rhodopseudo- concentration of metal ions. The model is taken to indicate that monas globiformis gave rise to the eukaryote mitochondria, probably

105 A82-20973 through at least three separate symbioses, one early on the flagellate determined from the physico-chemical properties of the car- line, one on the ciliate line, and one on the stem to the multicellular bonaceous compounds in aqueous media. M.S.K. forms. (Author) A82-21208 * Organic and inorganic interpretations of the A82-20973 On the origin of photosynthetic eukaryotic Martian UV-IR reflectance spectrum. K. D. Pang, J. M. Ajello cells - Cyanidium catdarium as a 'bridge' alga between prokaryotic (California Institute of Technology, Jet Propulsion Laboratory, cyanobacteria and eukaryotic rhodophytes: Evidence from environ- Pasadena, CA), S. F. S. Chun (California, University, San Francisco, mental, polysaccharide biochemistry and ultrastructural studies. J. CA), Z. Nansheng (Beijing Planetarium, Beijing, People's Republic of Seckbach (Jerusalem, Hebrew University, Jerusalem, Israel) and J. F. China), and L. Minji (Beijing Glass Institute, Beijing, People's Fredrick (Dodge Chemical Co., Bronx, NY). In: Origin of life; Republic of China). Nature, vol. 295, Jan. 7, 1982, p. 43-46. 45 refs. Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, NASA-sponsored research. Jerusalem, Israel, June 22-27, 1980. Dordrecht, Viking Lander biology experiment gas chromatography-mass D. Reidel Publishing Co., 1981, p. 567-574. 43 refs. spectrometer analysis has detected no organic molecules above a concentration of parts per billion. The questions considered here include the reason for the lack of organic molecules at the landing A82-20974 Microbial life in cold saline environments. S. sites, whether the sterility of the two sites is representative of the B. Leschine, K. J. Miller, and R. L. Huguenin (Massachusetts, whole of Mars, and whether there may be locations more conducive University, Amherst, MA). In: Origin of life; Proceedings of the to organic compound formation and preservation. After simulating Third ISSOL Meeting and Sixth ICOL Meeting, Jerusalem, Israel, the destruction of organic compounds in Mars-like laboratory June 22-27, 1980. Dordrecht, D. Reidel Publish- conditions and examining whether the destructive mechanism might ing Co., 1981, p. 575-582. 22 refs. obtain throughout the planet, UV and IR reflectance spectra are Microorganisms form Dry Valley (Antarctica) soils, from Great re-examined for any evidence of organic molecules and an upper Salt Lake (Utah, USA) water, and from refrigerated salt codfish were limit is determined for organic carbon content of average Martian enriched and isolated at 5 C in media containing high concentrations soil. It is found that the average Martian soil is poor in inorganics, of salts. The microbial flora that developed varied considerably presents a poor habitat for carbon chemistry-based life forms, and is depending on the source of the inoculum. A variety of morphologi- not likely to preferentially preserve such organisms anywhere on the cally distinct microorganisms was isolated. Most isolated strains grew over a wide range of temperature (e.g., 0-25 C) and salt concentra- planet. O.C. tion (e.g., 0.1-2 M NaCI) suggesting that the evolutionary strategy for adaptation of these organisms to low temperature and high salt A82-21213 Body temperature changes during the practice involved an increased tolerance of (rather than dependance on) these of g Tum-mo yoga. H. Benson, J. W. Lehmann (Beth Israel Hospital, extreme conditions. (Author) Boston, MA), M. S. Malhotra (IMetaji Subhas National Institute of Sports, Patiala, India), R. F. Goldman (U.S. Army, Research Institute of Environmental Medicine, Natick, MA), J. Hopkins A82-20975 * Mutagens and carcinogens - Occurrence and (Virginia, University, Charlottesville, VA), and M. D. Epstein role during chemical and biological evolution. A. Giner-Sorolla (Harvard University, Boston, MA). Nature, vol. 295, Jan. 21, 1982, (Sloan-Kettering Institute for Cancer Research, New York, NY) and p. 234-236. 16 refs. Research supported by the American Institute of J. Oro (Houston, University, Houston, TX). In: Origin of life; Indian Studies, Fleischmann Foundation, and Fetzer Foundation; Proceedings of the Third ISSOL Meeting and Sixth ICOL Meeting, NSF Grant No. INT-80-16982; Grants No. NIH-HL-22727; No. Jerusalem, Israel, June 22-27, 1980. Dordrecht, NIH-HL-07374. D. Reidel Publishing Co., 1981, p. 583-588. 28 refs. Grants No. It is reported that three practitioners of the Tibetan Buddhist NIH-CA-08748; No. NGR-44-005-002. meditational practice known as g Tum-mo, or heat yoga, have The roles of mutagenic and carcinogenic substances in early exhibited the capacity to deliberately increase the temperature of biologic evolution is examined, along with terrestrial and extra- their fingers and toes by as much as 8.3 C. Skin temperatures were terrestrial sources of mutagens and carcinogens. UV solar radiation is measured in the area of the navel and lumbar region, the nipple, the noted to have served to stimulate prebiotic life while also causing left forearm, the left fifth finger' nailbed, the left calf, the left toe harmful effects in plants and animals. Aromatic compounds have nailbed, and the forehead. The ages of the three subjects were 46, 50 been found in meteorites, and comprise leukemogens, polycyclic and 59 years. It is suggested that the physiological mechanism hydrocarbons, and nitrasamine precursors. Other mutagenic sources responsible for the marked increase of finger and toe temperature are volcanoes, and the beginning of evolution with mutagenic recorded is vasodilation. O.C. substances is complicated by the appearance of malignancies due to the presence of carcinogens. The atmosphere of the Precambrian period contained both mutagens and early carcinogens and, com- A82-21268 Microelectronics and computers in medicine. bined with volcanic activity discharges, formed an atmospheric J. D. Meindl (Stanford University, Stanford, CA). Science, vol. 215, chemical background analogous to the background ionizing radia- Feb. 12, 1982, p. 792-797. 56 refs. tion. Carcinogenesis is concluded to be intrinsic to nature, having Computer use in medicine and medical research is discussed, initiated evolution and, eventually, cancer cells. M.S.K. along with the applications of microelectronics in biosystems. Systems for experimentation demand consideration of the uses of microelectronic sensors for acquiring data bases and for implantable A82-20976 Could the biochemical metabolism be differ- telemetry. Data gathered from 'under the skin' are much harder than ent. R. Buvet (Paris XII, Universite, Creteil, Val-de-Marne, France). personal descriptions of medical history, and can be directly input to In: Origin of life; Proceedings of the Third ISSOL Meeting and Sixth a computer for analysis. The computer's role in medical decision- ICOL Meeting, Jerusalem, Israel, June 22-27, 1980. making processes is examined, including the implications of CAT Dordrecht, D. Reidel Publishing Co., 1981, p. scans as an effective diagnostic tool. Numerous routine and specially 589-599. 8 refs. ordered hospital tests can be automatically performed under compu- The inevitableness of life having formed from the reactivities of ter control, and the data stored, correlated, and selectively displayed carbonaceous molecules with derivatives of oxygen, sulfur, nitrogen, on demand. Additionally, results which are regarded as abnormal can phosphorus, and some metallic ions and complexes is examined. be scanned for automatically and the physician notified. M.S.K. Consideration is given to redox processes, condensations, the synthesis of chemical bonds, additional bonds, reciprocal elimina- tions, enol-oxo polymerizations, and the isoprenyl pyrophosphate A82-21454 t Electroencephalographic correlates of the polycondensations. Restrictions for biochemical processes are de- hemispheric functional asymmetry in the human brain (Elektroentse- fined, and standard potentials which define the transition from a falograficheskie korreliaty funktsional'noi asimmetrii bol'shikh polu- nonoxydized carbon atom to an alcohol or ethylenic group, alcohol sharii mozga cheloveka). E. A. Zhirmunskaia, V. S. Losev, and T. P. to an aldehydic or ketonic group, and an aldehydic group to a Evpakova (Kaunasskii Meditsinskii Institut, Kaunas, Lithuanian carboxylic group are explored. The transitions are found to occur at SSR). Uspekhi Fiziologicheskikh Nauk, vol. 13, Jan.-Mar. 1982, p. the lowest energy levels possible, considering that they take place at 42-65. 58 refs. In Russian. room temperature. Life then formed from reactions which were Recent work concerning the background electro-

106 A82-21679 encephalographic correlates of the functional asymmetry of the left parasympathetic hormones on the activity of the phosphorylase and right cerebral hemispheres connected with speech, visual, enzyme, which activates the cellular breakdown of glycogen. A.L.W. auditory or spatial perception, and other forms of mental activity is reviewed. Following a brief summary of current formulations of the A82-21470 t Filtration properties of receptive fields of problems of the relation of psychological and physiological phe- visual-cortex neurons (Fil'tratsionnye svoistva retseptivnykh polei nomena and hemispheric asymmetry in performing the same func- neironov zritel'noi kory). lu. E. Shelepin (Akademiia Nauk SSSR, tions on different levels, a review is presented of the goals, methods Institut Fiziologii, Leningrad, USSR). Akademiia Nauk SSSR, and results of experimental studies in the literature of the past 3-4 Doklady, vol. 261. no. 6, 1981, p. 1506-1509. 8 refs. In Russian. years. Attention is then given to the results of three series of An analysis is presented of the amplitude spatial-frequency experiments conducted by the present authors concerning the characteristics of the neuron receptive fields in the visual cortexes of general characteristics of EEC changes during changes in cerebral 35 cats. The general filtration properties (i.e., the isolation of spatial functional condition, EEC changes in different regions of the brain, frequency and image orientation) were determined for receptive and EEC changes in different cerebral functional conditions. The fields situated in various projection zones of the visual cortex, and a potential of electroencephalography for further studies of hemi- relationship between image orientation, spatial frequency, and spheric functional asymmetry and interactions is also discussed. neuron response was established, B.J. A.L.W.

A82-21455 t The structural and functional organization of A82-21676 Effects of long-term exposure to low levels of the ventrolateral nucleus of the thalamus' (Strukturno- ozone - A review. C. E. Melton (FAA, Civil Aeromedical Institute, funktsional'naia organizatsiia ventrolateral'nogo iadra talamusa). L. Oklahoma City, OK). Aviation, Space, and Environmental Medicine, V. Cherenkova and A. S. Batuev (Leningradskii Gosudarstvennyi vol. 53, Feb. 1982, p. 105-111. 39 refs. Universitet, Leningrad, USSR). Uspekhi Fiziologicheskikh Nauk, vol. Available literature regarding long-term effects of ozone on 13, Jan.-Mar. 1982, p. 66-88. 163 refs. In Russian. animals and humans is reviewed. This review shows that ozone Literature data concerning the structure and functional organi- concentration is more important than duration of exposure in zation of the ventrolateral nucleus (VLN) of th? thalamus and its determining the effects of an ozone exposure. This conclusion calls connections with various brain structures engaged in the processing into question the validity of the time-weighted average as an index of of information necessary for the integration of motor activity is severity of ozone exposure. The literature review further reveals a reviewed. The three types of neurons making up two zones of the wide variation in susceptibility of different animal species to ozone, VLN are distinguished, and connections of the VLN are examined, making it difficult to apply results of animal experiments to humans. including somatic afferents, afferents from the cerebellum, fornix, It further appears that a dose of ozone that is acutely innocuous is thalamic nuclei and cortex, and efferents to the sensorimotor cortex. also innocuous over the long term. The effects of a symptom- The structural data are noted to suggest that the VLN plays an producing dose of ozone are initially cumulative for the first two or important role in the organization of the cerebellar-thalamic-cortical three exposures; then an adaptive response may ensue that involves a system. Physiological data on neuronal activity, the control of plateau of response or even a reversal. These effects are shown by cerebellar impulse transmission, control on the part of the cortex and both animals and humans. The mechanisms are unknown. Ozone the role of the VLN in motor organization is considered, and the role probably causes damage by free radical formation. Free radical of the structure in filtering sensory information to allow the scavengers, such as vitamins E and C, may provide protection against initiation and realization of motion is.emphasized. A.L.W. ozone damage. (Author)

A82-21456 t Cellular mechanisms of the Frank-Starling A82-21677 A study of treadmill exercise protocols for phenomenon (Kletochnye mekhanizmy fenomena Franka-Starlinga). Chinese males. B.-L. Ho (Institute of Aviation Medicine, Taipei, V. la. Izakov, V. S. Markhasin, lu. L. Protsenko, and O. N. Republic of China). Aviation, Space, and Environmental Medicine, Bershitskaia (Sverdlovskii Nauchno-lssledovatel'skii Institut Gigieny vol. 53, Feb. 1982, p. 112-116. 14 refs. Research supported by the Tcuda i Profzabolevami, Sverdlovsk, USSR). UspeKUt Fizi- National Science Council of the Republic of China. ologicheskikh Nauk, vol. 13, Jan.-Mar. 1982, p. 89-108. 109 refs. In Russian. A82-21678 The effect of two years' training of aerobic Recent data concerning the cellular basis for the relation power and muscle strength in male and female cadets. W. L. Daniels, between length and tension discovered in skeletal and myocardial J. E. Wright, D. S. Sharp, D. M. Kowal, R. P. Mello, and R. S. muscle by Frank and serving as the basis of Starling's law of the heart Stauffer (U.S. Army, Research Institute of Environmental Medicine, is reviewed. The general characteristics of the relation between initial Natick, MA; U.S. Military Academy, West Point, NY). Aviation, muscle length and isometric contraction in skeletal muscle and the Space, and Environmental Medicine, vol. 53, Feb. 1982, p. 117-121. myocardium are discussed, and ultrastructural evidence is presented 10 refs. which shows that changes in the overlap between the thick and thin The considered investigation is concerned with a comparison of sarcomeric filaments are insufficient to explain the length-tension the responses of male and female cadets to extended military training relation. Studies of the influence of initial length on the calcium at the U.S. Military Academy. During the course of the study, the activation of myofibrils are then presented which demonstrate that training program of both male and female cadets was similar and, in inotropic factors act through both electromechanical coupling and some respects, identical. Volunteer cadets, 11 males and 7 females, calcium activation to influence contractile forces. A.L.W. completed all phases of this study. On all strength measures, the values for female cadets averaged approximately 30-40% lower than A82-21457 t Change in the cytochemical indicators of for males. The female cadets did not significantly narrow the gap carbohydrate metabolism in the peripheral blood neutrophils of with male cadets in terms of muscle strength and aerobic power, even pilots (Izmenenie tsitokhimicheskikh pokazatelei uglevodnogo ob- after 2 years of similar training. These results indicate that fnena neitrofilov perifericheskoi krovi letchikov). P. S. Pashchenko. post-pubertal females are unable to reduce the difference between Voenno-MeditsinskiiZhurnal, Dec. 1981, p. 52, 53. In Russian. themselves and males, even after extended training in a situation Glycogen levels and phosphorylase enzyme activities in the where many social, cultural, and environmental factors are very peripheral blood neutrophils of pilots are measured as indicators of similar. G.R. the effects of flight stress on carbohydrate metabolism and physiological condition in general. Blood samples were taken from 21 pilots A82-21679 Psychological testing at high altitudes. M. 1 to 1 1/2 hours before and 10 to 15 min after flight, and compared Nelson. Aviation, Space, and Environmental Medicine, vol. 53, Feb. with those of age-matched healthy controls. In 52% of the subjects, 1982, p. 122-126. 20 refs. preflight glycogen levels are found to be about equal to or even Psychological testing was done on 20 subjects at various exceed control values. Post-flight glycogen levels are observed to altitudes (sea level, 3,810 m, and 5,000 m) during a 35-d moun- depend on the preflight values, increasing in those with initially low taineering expedition to Denali (Mt. McKinley). Intellectual func- values, decreasing in those with slightly higher levels, and remaining tioning and personality changes were studied. While little variation the same for those with normal or greater than normal values. The was noted at the lower altitude, at 5,000 m there was a marked results are explained in terms of the effects of sympatho-adrenal and deterioration in cognitive ability. This was accompanied by a sharp

107 A82-21680

increase in paranoia and obsessive-compulsiveness and smaller in- A82-21684 Posturography of ataxia induced by Coriolis- creases in depression and hostility. (Author) and Purkinje-effects. C. Fitger and T. Brandt (Alfried Krupp von Bohlen und Halbach Krankenhaus, Essen, West Germany). Aviation, Space, and Environmental Medicine, vol. 53, Feb. 1982, p. 153-161. A82-21680 Effects of relative metabolic rate and heart 33 refs. Research supported by the Deutsche Forschungs- rate variation on the performance of flight attendants. T. Yoshioka, gemeinschaft. M. Narusawa, K. Nagami, C. Yabuki, Y. Nakahara, S. Nakano (Tokai One aim of the study is to provide information on clinical University, Isehara, Japan), C. Sekiguchi (Japan Air Self-Defense vertigo symptoms. Standing on a rotatable stabilometer, 25 healthy Force, Aeromedical Laboratory, Tachikawa, Japan), K. Noda (Japan subjects execute lateral head tilts during (Coriolis), or after (Pur- Air Line Co., Ltd., Health Control Service Div., Tokyo, Japan), T. kinje), rotation with different constant velocities. The conditions are Nagai, and Y. Kobayashi (Jikei University, Tokyo, Japan). Aviation, varied with respect to eyes open vs eyes closed, head upright vs head Space, and Environmental Medicine, vol. 53, Feb. 1982, p. 127-132. tilted to the right and left, direction of rotation (clockwise vs 15 refs. counterclockwise), head tilt (active vs passive), and body rotation (active vs passive). The results are as expected in that destabilization is less severe with open than closed eyes and that sway amplitudes A82-21681 Regional distribution of cardiac output in are increased after head tilt as well as with a higher velocity of unanesthetized baboons during +Gz stress with and without an rotation. The direction of the induced body shift is also as expected, anti-G suit. M. H. Laughlin, J. W. Burns, and M. J. Parnell (USAF, opposite to the initial vestibular stimulus. A forward shift after stop School of Aerospace Medicine, Brooks AFB, TX). Aviation, Space, without head tilt is frequently found, being independent of the and Environmental Medicine, vol. 53, Feb. 1982, p. 133-141. 43 refs. previous direction of rotation. Reported perceptions coincide mostly The F-16 and other recently developed high-performance not with the initial vestibular signal but with the actual movement of aircraft can produce levels of +Gz (head-to-foot acceleration) which compensation. C.R. may exeed man's physiologic tolerance for +Gz stress. In this connection, it is pointed out that the effects of +Gz on regional flow A82-21685 A statistical examination of three approaches and resistance in humans have remained a subject for conjecture. An for predicting motion sickness incidence. D. E. Smith (Desmatics, investigation was, therefore, conducted to obtain information regard- Inc., State College, PA). Aviation, Space, and Environmental ing this important subject. Eight female baboons were used in the Medicine, vol. 53, Feb. 1982, p. 162-165. 6 refs. Contract No. experiments, because the baboon is a subhuman primate which is N00014-74-C-0154. NR Project 207-037. phylogenetically close to man. The results of the experiments This paper examines three approaches which have been sug- demonstrate that, in baboons, +Gz stress causes a significant decrease gested for predicting motion sickness incidence (MSI) for actual or in cardiac output and a redistribution of blood flow away from simulated broadband ship motion. Although only a small amount of visceral organs. Acceleration exposure had no statistically significant empirical MSI data exists for motion other than that produced by a effect on blood flow to the cerebrum, cerebellum, or brain stem. single sinusoid, this data provides strong statistical evidence that two G.R. approaches based on single sinusoid models fail to produce accurate predictions. Statistical judgments about a least-squares weighting A82-21682 * The effects of horizontal body casting on approach must be reserved until enough data exists to provide an blood volume, drug responsiveness, and +Gz tolerance in the rhesus adequate test. In view of these results, it must be concluded that monkey. D. T. Dickey, G. E. Billman, K. Teoh, H. Sandier, and H. L. much empirical research remains to be done in order to develop a Stone (Oklahoma, University, Oklahoma City, OK). Aviation, Space, reasonably accurate method of predicting motion sickness incidence and Environmental Medicine, vol. 53, Feb. 1982, p. 142-146. 18 refs. for broadband motion. (Author) Grant No. NsG-2282. To simulate the weightless condition, eight rhesus monkeys, A82-21686 Difference between eye closure and visual instrumented with solid-state pressure transducers, were horizontally stabilization in the control of posture in man. P. P. Vidal, A. restrained in body casts for 28 days. Blood volume decreased an Berthoz, and M. Millanvoye (CNRS, Laboratoire de Physiologie average of 13% after 14 days of restraint, due mainly to a drop in Neurosensorielle; Conservatoire National des Arts et Metiers, Paris, plasma volume. Aortic pressure and heart rate responses to norepi- France). Aviation, Space, and Environmental Medicine, vol. 53, Feb. nephrine and phenylephrine decreased after 14 days of restraint. The 1982, p. 166-170. 11 refs. monkeys did not show a statistically significant decreased tolerance Stabilizing the visual surroundings of human subjects influences to a 90 deg sudden upright tilt after horizontal restraint. During the postural control during perturbations of their equilibrium. The fifth week of casting, four animals were subjected to +Gz accelera- latency of the first EMG burst is increased and its amplitude is tion tests on a centrifuge. The acceleration tolerance of the casted reduced. Body pitch is 36 percent stronger than with normal vision. monkeys was significantly reduced compared to four similarly Eye closure does not produce any significant modification of instrumented control animals. These findings indicate that the muscular responses and postural performance. This result explains cardiovascular deconditioning associated with simulated weight- why vision is not considered a rapid source of postural reaction. Eye lessness results from an inability to maintain central blood volume closure cannot be considered to be visual deprivation. (Author) during orthostatic stress. (Author) A82-21687 Cardiovascular origins of heatstroke pathophysiology - An anesthetized rat model. A. J. Kielblock, N. B. A82-21683 Acceleration induced voltage variations in the Strydom (Chamber of Mines Research Organization, Johannesburg, electrocardiogram during exhaustive simulated aerial combat maneu- Republic of South Africa), F. J. Burger, M. Manjoo (Durban- vering. J. E. Whinnery (USAF, School of Aerospace Medicine, Westville, University, Durban, Republic of South Africa), and P. J. Brooks AFB, TX). Aviation, Space, and Environmental Medicine, Pretorius (Potchefstroom University for Christian Higher Education, vol. 53, Feb. 1982, p. 147-152. 34 refs. Potchefstroom, Republic of South Africa). Aviation, Space, and A description is presented of the effects of exhaustive simulated Environmental Medicine, vol. 53, Feb. 1982, p. 171-178. 43 refs. aerial combat +Gz stress on the amplitudes of the P, QRS, and T A reappraisal of the nature and sequence of early circulatory waveforms as seen on the surface electrocardiogram. Twenty-two responses to heat stress is undertaken by subjecting male albino rats healthy males were exposed to an exhaustive simulated aerial combat to an environmental temperature of 45 C at 15% relative humidity maneuver (SACM) +Gz profile. It was found that marked changes in until overt circulatory failure occurs. Although the initial circulatory the electrocardiographic amplitudes occur as a result of exhaustive responses are normal for mild exertion, an inapparent circulatory SACM + Gz stress. Positional, pressure/volume, humoral and electro- crisis develops, which is thought to be a result of the abolishment of lyte changes may all be significant causative factors either alone or in compensatory splanchnic vascoconstriction. The impending threat of combination. Attention is given to T-wave response to exercise and functional hypovolemia is, temporarily at least, obscured by cardiac training, hyperkalemia as an etiology for T-wave changes, T-wave compensation; the extent of cardiovascular commitments may, response to +Gz stress, catecholamines as an etiology for T-wave therefore, have been underestimated. This also indicates that changes, QRS response to exercise and clinical considerations, and cardiovascular adjustments during the stress of heat may prove to be QRS response to+Gz stress. G.R. an essential feature of heatstroke pathophysiology. C.R.

108 A82-21709

A82-21688 The prevalence of visual deficiencies among sostavu). M. M. Ogievetskaia (Akademiia Nauk SSSR, Institut 1979 general aviation accident airmen. J. R. Dille and C. F. Booze, Khimicheskoi Fiziki, Moscow, USSR), O. D. Maslov (Ob'edinennyi Jr. (FAA. Civil Aeromedical Institute, Oklahoma City, OK). Avia- Institut ladernykh Issledovanii, Dubna, USSR), and N. S. Shelud'ko tion, Space, and Environmental Medicine, vol. 53, Feb. 1982, p. (Akademiia Nauk SSSR, Institut Biologii Moria, Vladivostok, USSR). 179-182. 5 refs. Biofizika, vol. 26, May-June 1981, p. 512-516. 7 refs. In Russian. The reported study of 1979 accidents shows that the relatively X-ray fluorescence analysis was used to perform a comparative small number of pilots with aphakia and artificial lens implants, as evaluation of the compositions of trace elements in phasic and tonic well as the total eye pathology population, had significantly higher muscles of the scallop Patinopecten Yessoensis. It is shown that the accident rates, but the monocular pilots did not. There are questions phasic muscles are richer in Fe and Cu, while the tonic muscles are about the functional importance of 20/30 and 20/40 best corrected richer in Zn, Br, and Sr; there is no difference in Rb content. The visual acuity in one case, and entry of 'no fusion' in another, and the results make it possible to classify Fe, Cu, Zn, Br, and Sr according dynamic, peripheral, depth and accommodative performance of to their properties connected with various homeostatic requirements several with appreciable pathology who have a corrected central of the muscles with respect to the trace elements. B.J. acuity of 20/20. It is recommended to continue investigations of the considered type. The obtained findings should be taken into account A82-21705 t Rhodopsin aggregation under the damaging in the design of research on contemporary problems in aviation effects of light on the photoreceptor membranes (Agregatsiia medicine. Meanwhile, continuing emphasis must be placed on the molekul rodopsina pri povrezhdaiushchem deistvii sveta na foto- accurate measurement of visual functions required for medical retseptornye membrany). I. D. Pogozheva, V. A. Kuznetsov, I. B. certification in communications with FAA aviation medical examin- Fedorovich, V. A. Livshits, M. A. Ostrovskii, and N. M. Manoshkina ers. G.R. (Akademiia Nauk SSSR, Institut Khimicheskoi Fiziki, Moscow, USSR). Biofizika, vol. 26, July-Aug. 1981, p. 692-700. 20 refs. In A82-21701 t The economy of muscular work during un- Russian. fused tetanus (Ekonomichnost' raboty myshts v rezhime zubchatogo Rhodopsin aggregation and structural changes in the photo- tetanusa). V. S. Gurfinkel' and lu. S. Levik (Akademiia Nauk SSSR, receptor membranes under the damaging effects of visible light are Institut Problem Peredachi Informatsii, Moscow, USSR). Biofizika, investigated. The rotational mobility of spin-labeled rhodopsin in the vol. 26, Mar.-Apr. 1981, p. 371-373. In Russian. photoreceptor membrane was studied by means of saturation- The economy of skeletal muscle work, defined as the relation transfer ESR spectroscopy, and concentrations of various rhodopsin between tension produced and energy utilized in a given time, during oligomers, rhodopsin SH-group oxidation levels and the degree of the three stages of unfused tetanus in humans is investigated. lipid membrane peroxidation were determined in suspensions of frog Measurements of intramuscular temperature were made under local outer segment rods irradiated at 100,000 lux. Photooxidation of the blood arrest during sustained isometric tetanus of the flexor photoreceptor membrane is found to lead to a reduction in digitorum superficialis stimulated at a frequency of 9.5 pulses/sec, rhodopsin mobility within the membrane which is attributed to the and compared with measurements of the tension of the second irreversible molecular aggregation as a result of the formation of phalange of the fourth finger. The rate of temperature rise is found disulphide bonds between hydrophobic SH groups on the rhodopsin to be greatest in tetanus phase II, which is characterized by the molecule. A decrease in lipid micrqviscosity and degree of order is largest tension oscillations and extends from the 5th to the 30th observed upon membrane photodestruction, in contrast to the second of contraction. The economy of muscle contraction is significant increase in microviscosity observed upon oxidation in the accordingly 1.3 to 1.7 times lower at this stage than at the beginning presence of Fe ions. Lipid oxidation is also shown to accelerate of tetanus. In phase III, where increased mechanical efficiency is protein aggregation, which in turn influences the lipid bilayer. A. LW. obtained, the muscle economy is also found to rise progressively, reaching a final level 3.5 times greater than initial by the 40-50th A82-21706 t The relationship between carbohydrate and second of contraction. A.L.W. lipid metabolisms in muscle cell energetics under the influence of ATPase loading - Mathematical model (Sootnoshenie uglevodnogo i lipidnogo obmenov v energetike myshechnykh kletok pri deistvii A82-21702 t A mathematical model of cell populations ATFaznoi nagruzki - Matematicheskaia model). V. V. Dynnik with stem cells (Matematicheskaia model' kletochnoi populiatsii so (Akademiia Nauk SSSR, Institut Biologicheskoi Fiziki, Pushchino, stvolovymi kletkami). A. IM. Zhabotinskii (Nauchno-lssledovatel'skii USSR). Biofizika, vol. 26, July-Aug. 1981, p. 712-718. 17 refs. In Institut po Biologicheskim Ispytaniiam Khimicheskikh Soedinenii, Russian. Kupavna, USSR). Biofizika. vol. 26, Mar.-Apr. 1981, p. 329-332. 7 refs. In Russian. The principal properties of stationary tissue populations are A82-21707 t The dynamics of muscular relaxation follow- explained within the framework of a hypothesis stating that the ing unfused tetanuses of different durations (Dinamika myshechnogo binding of chalone, a tissue inhibitor, by a stem cell results in rasslableniia posle zubchatykh tetanusov razlichnoi dlitel'nosti). V. S. asymmetric cell division with the formation of a daughter stem cell Gurfinkel' and lu. S. Levik (Akademiia Nauk SSSR, Institut Problem and a partially differentiated cell. A chalone-free stem cell divides Peredachi Informatsii, Moscow, USSR). Biofizika, vol. 26, July-Aug. symmetrically yielding two daughter stem cells. V.L 1981, p. 709-711.10 refs. In Russian.

A82-21703 t Functional model of the conversion of station- A82-21708 t Effect of calcium on the temporal character- ary signals in the auditory analyzer (Funktsional'naia model' istics of muscle contraction (Vliianie kal'tsiia na vremennye kharak- preobrazovaniia statsionarnykh signalov v slukhovom analizatore). E. teristiki myshechnogo sokrashcheniia). A. E. Bukatina, M. F. Chaplii, G. Karnitskaia (Akademiia Nauk SSSR, Institut Fiziologii, Lenin- and L. L. Alievskaia (Akademiia Nauk SSSR, Institut Biologicheskoi grad, USSR). Biofizika, vol. 26, May-June 1981, p. 517-521. 14 refs. Fiziki, Pushchino, USSR). Biofizika, vol. 26, July-Aug. 1981, p. In Russian. 749-751. 15 refs. In Russian. A model for spectral processing in the auditory analyzer is It is shown that the time constant of the delayed tension of m. developed which consists of three layers: (1) a layer of filters whose psoas fibers in rabbits increases with calcium concentration in the characteristics imitate the masking curves; (2) a layer of nonlinear medium, this dependence becomes less pronounced in the presence converters whose nonlinearity parameters are chosen in such a way of inorganic phosphate. Results of the study suggest a possible link that the calculated results correspond to the basic characteristics of between bridges via a reaction product. V.L. the perception of stationary-signal loudness; and (3) a layer of lateral inhibition. This model can distinguishthe formant structure of sound in a synthetic speechlike signal; at low-frequencies up to 1000 Hz the A82-21709 t The possibility of using mathematical methods first harmonics are distinguished in addition to the formants. B.J. for predicting the results of the surgical treatment of patients with vasorenal hypertension (O vozmozhnosti ispol'zovaniia matemati- cheskikh metodov dlia prognozirovaniia rezul'tatov khirurgicheskogo A82-21704 t Differentiation of muscles on the basis of lecheniia bol'nykh vazorenal'noi gipertoniei). G. S. Krotovskii, M. M. trace-element composition (Razlichiia myshts po mikroelementnomu Ellanskii, A. N. Shcherbiuk, S. A. Turpitko, and S. V. Suris (I

109 A82-21710

Moskovskii Meditsinskii Institut, Moscow, USSR). Kardiologiia. vol. (Osobennosti stroeniia srednego ukha gryzunov kak pokazatel' 21, Mar. 1981, p. 32-35. In Russian. chastotnoi nastroiki slukhovoi sistemy). V. N. Movchan and I. N. Orlova. Leningradskii Universitet, Vestnik, Biologiia, Aug. 1981, p. A82-21710 t Investigation and evaluation of cardiac 85-90. 17 refs. In Russian. arrhythmias in healthy young persons (Issledovanie i otsenka narushenii ritma serdtsa u molodykh zdorovykh liudei). A. G. A82-21715 t Adaptation to high-altitude hypoxia at dif- Dembo and E. V. Zemtsovskii (Leningradskii Institut Fizicheskoi ferent ambient temperatures /before and during adaptation/ (Ad- Kul'tury, Leningrad, USSR). Kardiologiia, vol. 21, Oct. 1981, p. aptatsiia k gornoi gipoksii v usloviiakh raznykh /predvariaiushchei i 51-55. 23 refs. In Russian. soprovozhdaiushchei/ temperatur vneshnei sredy). I. B. Khodzham- The incidence of cardiac arrhythmias in athletes was investigated berdiev, N. M. lartsev, A. A. Altymyshev. and A. A. Aidaraliev by performing EKG examinations (continuous recording of 100 (Akademiia Nauk Kirgizskoi SSR, Institut Organicheskoi Khimii, cardiac cycles) on 1293 young athletes and 482 young nonathletes. Frunze, Kirgiz SSR). Akademiia Nauk Kirgizskoi SSR, Izvestiia, The athletes were found to have disorders of the heart rhythm in a Mar.-Apr. 1981, p. 55, 56. 6 refs. In Russian. statistically significant higher proportion of cases. Depressed activity Rats and male rabbits were tested for adaptation to high-altitude of the sinus pacemaker was especially common, indicating arrhyth- hypoxia at ambient temperature ranges of 9-13 C and 22-27 C. It is mias of the depressed sinus node and extrasystoles. These disorders found that distrophic processes in the myocardium, kidneys, and are due to pathological changes related to the foci of chronic skeletal muscles are exacerbated during adaptation in the lower- infections, myocardial dystrophy due to chronic physical overexer- temperature range. BJ. tion, and marked myoeardial hypertrophy. B.J. A82-21716 t Functional characteristics of receptors con- A82-21711 t Changes in the main characteristics of the nected with sustaining the flight of the roach Periplaneta Americana central hemodynamics of healthy individuals and hypertension L (Funktsional'nye osobennosti retseptorov, sviazannykh s podder- patients during physical exercise (Izmenenie osnovnykh pokazatelei zhaniem poleta tarakana Periplaneta Americana L). S. V. lagodin and tsentral'noi gemodinamiki u zdorovykh i bol'nykh gipertonicheskoi V. L. Sviderskii (Akademiia Nauk SSSR, Institut Evoliutsionnoi bolezn'iu pri fizicheskoi nagruzke). A. I. Minovich and T. G. Fiziologii i Biokhimii, Leningrad, USSR). Akademiia Nauk SSSR, Vatsadze (Akademiia Nauk Gruzinskoi SSR, Institut Klinicheskoi i Doklady, vol. 250, no. 5, 1980, p. 1277-1280. 14 refs. In Russian. Eksperimental'noi Kardiologii, Tiflis, Georgian SSR). Kardiologiia, vol. 21, Mar. 1981, p. 44-47. 17 refs. In Russian. A82-21717 t Evaluation of safety of decompression from A82-21712 t The role of natriuresis in the prophylactic the critical volume of gas bubbles formed in the organism (Printsip effect of adaptation to hypoxia in the case of hereditary hyperten- otsenki bezopasnosti dekompressii po kriticheskomu ob'emu gazo- sion (Rol' natriiureza v profilakticheskom effekte adaptatsii k vykh puzyr'kov, obrazovavshikhsia v organizme). V. P. Nikolaev gipoksii pri nasledstvennoi gipertonii). F. Z. Meerson, N. A. (Ministerstvo Zdravookhraneniia SSSR, Institut Mediko- Barbarash, G. la. Dvurechenskaia, and N. S. Prokina (Akademiia Biologicheskikh Problem, Moscow, USSR). Akademiia Nauk SSSR, Meditsinskikh Nauk SSSR, Moscow; Kemerovskii Meditsinskii Insti- Doklady, vol. 255, no. 1, 1980, p. 246-249. 12 refs. In Russian. tut, Kemerovo, USSR). Kardiologiia, vol. 21, July 1981, p. 25-32. 27 A decompression safety criterion is proposed whereby decom- refs. In Russian. pression is considered safe if no tissue of the human organism Experiments on male Wistar rats and rats with spontaneous contains more than the critical amount of gas bubbles which varies hereditary hypertension (SHH) showed that the development of SHH with tissue types. The proposed criterion is shown to be valid for was accompanied by a significant decrease in the renal excretion of both multiple-step and single-step decompression. V.L. water and sodium. Acute hypoxia in Wistar rats resulted in a significant decrease in diuresis, glomerular filtration, and K and (insignificantly) Na excretion, while in SHH rats acute hypoxia A82-21718 t The dynamics of protein and nucleic acid increased diuresis significantly and enhanced Na and K excretion. content in rat raphe nucleus cells after total deprivation of sleep /in a Adaptation to hypoxia during six hours per day resulted in an rotating cylinder/ and selective deprivation of its paradoxical phase increase of diuresis, glomerular filtration, Na excretion, and the Na/K (Dinamika soderzhaniia belkov i nukleinovykh kislot v kletkakh iader coefficient of urine in both Wistar and SHH rats. During the first shva krysy pri polnom lishenii sna /v tretbane/ i selektivnom lishenii month of adaptation changes were more pronounced in SHH rats ego paradoksal'noi fazy). U. M. Malikov and A. N. Panov (Akademiia than in Wistar rats; as a consequence, the hypertension did not Nauk SSSR, Institut Fiziologii, Leningrad, USSR). Akademiia Nauk develop in SHH rats. It is concluded that the natriuretic effect is SSSR, Doklady, vol. 257, no. 2, 1981, p. 501-503. 15 refs. In probably the main mechanism of the prophylactic effect of Russian. adaptation to hypoxia on the development of hereditary hypertension. B.J. A82-21719 t Oxygen transport in dogs native to high A82-21713 t The effect of motor activity on the develop- altitudes during exercise (Transport kisloroda u sobak-aborigenov ment of cardiac arrhythmias in experimental emotional stress vysokogor'ia pri fizicheskikh nagruzkakh). M. V. Balykin (Akademiia (Vliianie dvigatel'noi aktivnosti na vozniknovenie serdechnykh Nauk Kirgizskoi SSR, Institut Fiziologii i Eksperimental'noi Patologii aritmii pri eksperimental'nom emotsional'nom stresse). L. S. Ul'ia- Vysokogor'ia, Kirgiz SSR). Akademiia Nauk Kirgizskoi SSR, Izve- ninskii, T. G. Urmancheeva, E. P. Stepanian, A. A. Fufacheva, A. V. stiia, Mar.-Apr. 1981, p. 66-72. 24 refs. In Russian. Gritsak, B. A. Kuznetsova, and A. A. Kvitka (Akademiia Meditsin- Parameters characterizing oxygen transport during exercise of skikh Nauk SSSR; Moskovskii Inzhenerno-Fizicheskii Institut, Mos- stepwise increasing intensity are investigated in dogs native to high cow, USSR; Akademiia Meditsinskikh Nauk SSSR, Sukhumi, Geor- altitudes. Measurements of blood pH, oxygen and carbon dioxide gian SSR). Kardiologiia, vol. 21, Oct. 1981, p. 64-67. 18 refs. In tensions, acid-base balance, temperature and hemoglobin concentra- Russian. tion in arterial and venous blood were made in dogs native to Investigations on monkeys and rabbits have shown that emo- altitudes of 760 m and 2700 m at rest and during 10-min recovery tional stress can produce various disorders of the heart rhythm: sinus periods between treadmill exercise at speeds of 5, 10, 15 and 20 tachycardia, atrial fibrillation, ventricular extrasystoles, and paroxys- km/h. At rest, the high-altitude dogs exhibit a shift in acid mal ventricular tachysystoles. Under these conditions the adrenaline base-balance towards the side of respiratory alkalosis with respect to content in the blood and myocardium increases three-to-four times, the controls, as well as high arterial blood oxygenation and oxygen while the noradrenaline level increases in the blood and decreases in utilization in the presence of reduced oxygen transport. Moderate the myocardium. Marked motor activity leads to an increase of the exercise under low-altitude conditions is observed not to decrease adrenaline and noradrenaline level in the myocardium and to the arterial blood oxygenation, while intense muscular work may lead to development of disorders of cardiac rhythm including ventricular arterial hypoxemia. Exercise in mountain natives, however, induces a fibrillation. B.J. slight reduction in arterial oxygenation and a marked venous hypoxemia. Results demonstrate the efficiency of the respiratory A82-21714 t Peculiarities of the middle ear structure in and circulatory systems of high-altitude natives during exercise. rodents as an index of the frequency tuning of their auditory system A.L.W.

110 A82-21730

A82-21720 t Disturbances in biological rhythms as a result Meditsinskii Institut, Odessa, Ukrainian SSR). Radiobiologiia, vol. of a conflict of incompatible stimuli (Narusheniia biologicheskikh 21, July-Aug. 1981, p. 598-602. 12 refs. In Russian. ritmov kak rezul'tat konflikta nesovmestimykh pobuzhdenii). V. A. Zotov and V. A. Nepomniashchikh (Moskovskii Gosudarstvennyi A82-21726 t Changes in morphological and cytogenetic Universitet, Moscow, USSR). Zhurnal Obshchei Biologii, vol. 42, hematopoietic indicators in hamadryas baboons exposed to chronic July-Aug. 1981, p. 622-627. 5 refs. In Russian. low-level radiation (Izmeneniia morfologicheskikh i tsitogeneti- The organization of the groups of oscillators believed to control cheskikh pokazatelei krovetvornoi sistemy u pavianov gamadrilov pri the rhythmic activities of an organism is investigated in studies of the khronicheskom obluchenii v malykh dozakh). E. K. Dzhikidze, M. I. consequences of the superposition of incompatible stimuli. The Kuskova, and L. P. Kosichenko (Akademiia Meditsinskikh Nauk characteristics of foreleg cleaning behavior in the mite Varroa SSSR, Sukhumi, Georgian SSR). Radiobiologiia, vol. 21, Sept.-Oct. jacobsoni and of the circadian motility cycle in the beetle Tri- 1981, p. 705-711. 9 refs. In Russian. gonoscelis gigas were observed under stressful conditions: isolation from the host in the first case and constant temperature and A82-21727 t Auditory depth perception - Localization of illumination in the second. The experiments have shown the nonmoving and moving sound sources (Prostranstvennyi slukh - behavioral acts consisting of the cleaning of the right and left limbs Lokalizatsiia nepodvizhnykh i dvizhushchikhsia istochnikov zvuka). in mites and burrowing into the soil and emerging from it in beetles la. A. Al'tman (Akademiia Nauk SSSR, Institut Fiziologii, Lenin- to be under the control of separate oscillators, as they are grad, USSR). Uspekhi Fiziologicheskikh Nauk, vol. 12, Oct.-Dec. characterized by different periodicities. As the phases of the rhythms 1981, P. 28-51. 76 refs. In Russian. controlled by these oscillators begin to overlap, conflict behavior is The literature on the localization of nonmoving and moving observed, and arrhythmias and other disturbances of the rhythm sound sources is surveyed in an effort to study the basic characteris- appear. A.L.W. tics of the depth perception of moving sources. It is shown that there is a critical time interval for the formation of the perception of A82-21721 t Characteristics and patterns of the individual development of male and female rats in the light of the energy rule moving sources. The differential sensitivity of the auditory system of skeletal muscles (Osobennosti i zakonomernosti 'mdividual'nogo for the perception of moving sources is higher than for the razvitiia samtsov i samok krys v svete energeticheskogo pravila localization of nonmoving sources. The neurophysiological aspects of skeletnykh myshts). I. A. Arshavskii, V. D. Rozanova, and T. G. the spatial localization of moving sound sources are examined with Savkiv (Akademiia Meditsinskikh Nauk SSSR, Moscow, USSR). particular attention given to the role of central auditory neurons. B.J. Zhurnal Obshchei Biologii, vol. 42, Sept.-Oct. 1981, p. 698-707. 21 refs. In Russian. A82-21728 t Pulmonary shunting and its regulation (Legochnyi shunt i ego reguliatsiia). L. G. Dukov (Smolensk!! A82-21722 t Introduction prognosis and its methodological Meditsinskii Institut, Smolensk, USSR). Uspekhi Fiziologicheskikh aspects (Introduktsionnyi prognoz i ego metodicheskie aspekty). S. Nauk, vol. 12, Oct.-Dec. 1981, p. 112-128. 104 refs. In Russian. E. Korovin and A. S. Demidov (Akademiia Nauk SSSR, Glavnyi On the basis of studies of ventilation-perfusion relationships, Botanicheskii Sad. Moscow, USSR). Zhurnal Obshchei Biologii, vol. recent data on the mechanisms governing the development and 42, Sept.-Oct. 1981, p. 673-679. 17 refs. In Russian. regulation of pulmonary shunting are presented. The ability of The present status, together with the prospects for development existing techniques to measure and separate the shunting is discussed of introduction prognosis is considered. Factual material is presented in detail. It is found that in healthy subjects shunting derives from showing the possibility of predicting the reactions of subtropical two causes. The first is an anatomic shunting, that is, the discharge of plants to the conditions under which they are introduced. The venous blood through bronchial veins into the pulmonary veins and predictions are based on a method of ecological and geographical along the thebesian channels into the left heart. The second is a comparisons. C.R. ventilation-perfusion irregularity, that is, the perfusion of hypoven- tilated alveoli. Attention is also given to the mechanisms controlling A82-21723 t Absence of the additive effect in the combined pulmonary shunting, namely collateral ventilation, pulmonary hy- irradiation of Crepis capillaris seeds and seedlings by gamma rays and poxic vasoconstriction, and bronchoconstriction from hypocapnia. neutrons (Otsutstvie additivnogo effekta pri kombinirovannom oblu- C.R. chenii semian i prorostkov Crepis capillaris gamma-luchami i neitro- nami). E. V. Fesenko and N. V. Luchnik (Akademiia Meditsinskikh A82-21729 t A systems analysis of human motor reactions Nauk SSSR, Obninsk, USSR). Radiobiologiia, vol. 21, July-Aug. in various modes of operation of goal-directed behavioral acts 1981, p. 630-632. 11 refs. In Russian. (Sistemnyi analiz dvigatel'nykh reaktsii cheloveka v raznykh rezhi- makh raboty tselenapravlennogo povedencheskogo akta). 0. la. A82-21724 T Some indicators of protein metabolism in Bokser (Akademiia Meditsinskikh Nauk SSSR, Moscow, USSR) and erythrocytes during radiation sickness and following cystamine K. V. Sudakov (Ivanovskii Meditsinskii Institut, Ivanovo, USSR). injection (Nekotorye pokazateli belkovogo obmena v eritrotsitakh Uspekhi Fiziotogicheskikh Nauk, vol. 12, Jan.-Mar. 1981, p. 3-31. pri luchevoi bolezni i vvedenii tsistarnina). I. A. Serebrennikova and 125 refs. In Russian. N. I. Kolesova (Tomskii Meditsinskii Institut, Tomsk, USSR). The way in which goal-directed activity in humans is ensured Radiobiologiia, vol. 21, July-Aug. 1981, p. 577-581. 17 refs. In somatically and autonomically on the basis of a temporal organiza- Russian. tion of start and stop signals is investigated. Laws are established for The effects of high-energy betatron irradiation and the pre- the programming of the results of the working of the space-time liminary injection of cystamine on erythrocyte protein metabolism continuum of stage results and effector components directed toward are investigated. Determinations of total, amine, urea and residual the attainment of a finite adaptive effect that is characteristic of each nitrogen, free amino acid, and proteolytic enzyme activities were type of behavioral act investigated. C.R. made in rabbits before and up to 30 days after exposure to 10 gram-roentgens of 25-MeV betatron radiation. Ionizing radiation is found to lead to the activation of erythrocyte proteolytic enzymes, A82-21730 t The dynamics of forming a prediction system resulting in the breakdown of endogenous proteins and an increase in in goal-directed behavior (Dinamika formirovaniia apparata prog- the nitrogenous products of protein metabolism. The preliminary nozirovaniia v tselenapravlennom povedenii). G. N. Rychkova (Aka- intravenous injection of cystamine reduces the deleterious effects of demiia Meditsinskikh Nauk SSSR, Moscow, USSR). Uspekhi Fiziolo- radiation on protein metabolism, and increases the survival rate after gicheskikh Nauk, vol. 12, Oct.-Dec. 1981, p. 99-111. 37 refs. In 30 days from 67 to 82%. A. LW. Russian. A hypothesis describing a dynamic principle at work in the A82-21725 t Characteristics of the relations of the primary formation of a system for prediction is elaborated. The stage of responses of the pentose phosphate pathway to glycolysis in the generalization involves the setting up of an inexact and redundant bone marrow of irradiated rats (Osobennosti vzaimosviazi vazhnei- reinforcement model in the acceptor for evaluating the results of shikh reaktsii pentozofosfatnogo puti s glikolizom v kostnom mozge actions; here, ineffective methods of attaining goals prevail. In the obluchennykh krys). I. V. Savitskii and V. K. Napkhaniuk (Odesskii stage of concentration, a precise reinforcement model is set up, and

111- A82-21731 there are effective means of attaining goals. The system for pronitsaemost' membran eritrotsitiv, rekonstruirovannykh v sredakh prediction evolves by means of a mechanism of orienting and razlichnogo ionnogo sostava). A. K. Gulevskii (Akademiia Nauk exploratory reactions; these arise from discrepancies between the Ukrainskoi SSR, Institut Problem Kriobiologii i Kriomeditsiny, predicted and the actual. The evolution also depends on a system of Kharkov, Ukrainian SSR). Biulleten' Eksperimental'noi Biologii i positive and negative emotions that operates simultaneously. C.R. Meditsiny, vol. 91, May 1981, p. 551-553. 9 refs. In Russian.

A82-21731 t Study of the electrical activity of the extra- A82-21738 t The effect of blood pressure in the pulmonary ocular muscles (Issledovanie elektricheskoi aktivnosti vneshnikh artery on gas exchange in functionally heterogeneous lungs (Vliianie glaznykh myshts). R. B. Nebieridze (Akademiia Nauk Gruzinskoi davleniia krovi v legochnoi arterii na gazoobmen v funktsional'no SSR, Institut Kibernetiki, Tiflis, Georgian SSR). Uspekhi Fiziologi- neodnorodnykh legkikh). A. I. D'iachenko (Moskovskii Fiziko- cheskikh Nauk, vol. 12, Jan.-Mar. 1981, p. 119-132. 84 refs. In Tekhnicheskii Institut, Moscow, USSR). Biulleten' Eksperimental'noi Russian. Biologii i Meditsiny, vol. 91, May 1981, p. 564-566. 6 refs. In The characteristics of the electrical activity associated with the Russian. extraocular muscles in tonus and during tracking and saccadic eye The blood pressure in the common pulmonary artery in humans movements are discussed on the basis of experimental and literature is determined on the basis of measurements of the alveolar-arterial data. Electromyographic studies of the motor units of the ocular difference in oxygen pressures and the arterial-alveolar difference in muscles are considered, and morphological and physiological evi- carbon dioxide pressures. The study is carried out for a variety of gas dence for the existence of two types of motor units, tonic and compositions of mixed venous blood and at different levels of lung phasic, in the extraocular muscles is reviewed. On the basis of this ventilation. A mathematical model for the operation of hetero- evidence, it is proposed that rather than there being units functioning geneous lungs is used. The model consists of three parts, describing either to maintain tonus or induce movements, there exists one type blood flow, ventilation, and gas exchange in individual lobules; it also of motor unit functioning at rest and during the fast and slow phases includes equations of the gas composition average of arterial blood of nystagmus, and a second type functioning only during the fast and alveolar air. C.R. phase of nystagmus, primarily during large-amplitude saccades. The characteristics of motorneuron control of tracking and saccadic eye A82-21739 t Change in the nature of the psychotropic movements are also discussed. A.L.W. effect on the emotional reactivity and behavior in stress situations depending on the state of the catecholaminergic systems of the brain A82-21732 t The effect of cold stress on the level and (Izmenenie kharaktera psikhotropnogo effekta na emotsional'nuiu activity of microsomal cytochrome P-450 in the rat liver (Vliianie reaktivnost' i povedenie v stress-situatsii v zavisimosti ot sostoianiia kholodovogo stressa na soderzhanie i aktivnost' mikrosomal'nogo katekholaminergicheskikh sistem mozga). N. A. Bondarenko, A. V. tsitokhroma P-450 pecheni krys). L. I. Deev, M. la. Akhalaia, and lu. Validman, and V. A. Kamysheva (Akademiia Meditsinskikh Nauk B. Kudriashov (Moskovskii Gosudarstvennyi (Jniversitet, Moscow, SSSR, Moscow, USSR). Biulleten' Eksperimental'noi Biologii i USSR). Biulleten' Eksperimental'noi Biologii i Meditsiny, vol. 92, Meditsiny, vol. 92, July 1981, p. 35-38. 15 refs. In Russian. Aug. 1981, p. 28-30. 15 refs. In Russian.

A82-21733 t The correlation between hematologic and bio- A82-21740 t Effect of cooling of the rhythmo-inotropic chemical indicators in the turtles Testudo horsfieldi (Korre- ratio in a pathologically altered myocardium (Vliianie okhlazhdeniia liatsionnye sviazi mezhdu gematologicheskimi i biokhimicheskimi na ritmo-inotropnye otnosheniia v patologicheski izmenennom pokazateliami u cherepakh Testudo horsfieldi). L. A. Tiunov, V. A. miorarde). E. G. Vornovitskii, V. B. Ignat'eva, A. N. Kaidash, A. D. Ivanova, A. I. Kliorin, A. A. Turdyev, and V. P. Timofeev. Biulleten' Arapov, and E. B. Mogilevskii (Akademiia Meditsinskikh Nauk SSSR, Eksperimental'noi Biologii i Meditsiny, vol. 92, July 1981, p. 47-49. Moscow, USSR). Biulleten' Eksperimental'noi Biologii i Meditsiny, 12 refs. In Russian. vol. 92, July 1981, p. 10-14. 12 refs. In Russian. Experiments are described showing that.the blood, even though having a low level of erythrocytes, has a high content of hemoglobin. A82-21741 t The effect of synaptically active drugs on the This is interpreted to mean that the low number of erythrocytes is hyperthermic effect of prostaglandin E2 in rats (Vliianie sinapti- balanced by a high degree of hemoglobin saturation. The concen- cheski aktivnykh veshchestv na gipertermicheskii effekt prostaglan- tration of leukocytes in the blood is found to be relatively high. C.R. dina E2 u krys). V. N. Gurin, f. E. Vismont, and V. V. Tsariuk (Minskii Meditsinskii Institut, Minsk, Belorussian SSR). Biulleten' A82-21734 t Activation of succinate dehydrogenation in rat Eksperimental'noi Biologii i 'Meditsiny, vol. 91, Mar. 1981, p. 304, liver by noradrenalin, cAMP and acute cooling (Aktivatsiia degidriro- 305. 14 refs. In Russian. vaniia suktsinata v pecheni krys pod vliianiem noradrenalina, tsAMF i ostrogo okhlazhdeniia). V. I. Kulinskii, A. K. Kuntsevich, and L. V. A82-21742 t An investigation of the biological activity of Trufanova (Krasnoiarskii Meditsinskii Institut, Krasnoyarsk, USSR). chalones separated from normal livers and from livers that are Deing Biulleten' Eksperimental'noi Biologii i Meditsiny, vol. 92, Aug. 1981, regenerated (Izuchenie biologicheskoi aktivnosti keilonov, vydelen- p. 33, 34. 15 refs. In Russian. nykh iz normal'noi i regeneriruiushchei pecheni). S. A. Ketlinskii and E. V. Parfenova (Akademiia Meditsinskikh Nauk SSSR, Leningrad, A82-21735 t The effect of low temperature on the activity USSR). Biulleten' Eksperimental'noi Biologii i Meditsiny, vol. 92, and substrate specificity of monoamine oxidases in rat brain July 1981, p. 96-98. 6 refs. In Russian. mitochondria (Vliianie nizkoi temperatury na aktivnost' i substrat- nuiu speksifichnost' monoaminoksidaz v mitokhondrial'noi fraktsii A82-21743 t The circadian rhythm of activity of adrenergic mozga krys). I. A. Goroshinskaia, A. A. Krichevskaia, and Z. G. nerve fibers in the dura mater of rats (Sutochnyi ritm aktivnosti Bronovitskaia (Rostovskii Gosudarstvennyi Universitet, Rostov-on- adrenergicheskikh nervnykh volokon tverdoi mozgovoi obolochki Don, USSR). Biulleten' Eksperimental'noi Biologii i Meditsiny, vol. krys). V. S. Karedina (Vladivostokskii Meditsinskii Institut, Vladi- 91, Apr. 1981, p. 431-433. 14 refs. In Russian. vostok, USSR). Biulleten' Eksperimental'noi Biologii i Meditsiny, vol. 92, Oct. 1981, p. 485, 486. 5 refs. In Russian. A82-21736 t Peroxidation of lipids in the liver and lungs of rats during prolonged adaptation to the cold (Reaktsii perikisnogo okisleniia lipidov v pecheni i legkikh krys pri dolgovremennoi A82-21744 t A histochemical investigation of the micro- adaptatsii k kholodu). N. G. Kolosova, lu. P. Shorin, and V. lu. vascular effectors regulating the supply of blood to the cerebral Kulikov (Akademiia Meditsinskikh Nauk SSSR, Novosibirsk, USSR). cortex (Gistokhimicheskie issledovaniia mikrovaskuliarnykh ef- Biulleten' Eksperimental'noi Biologii i Meditsiny, vol. 91, Apr. 1981, fektorov regulirovaniia krovosnabzheniia kory golovnogo mozga). D. p. 436, 437. 10 refs. In Russian. G. Baramidze, R. Gadamskii, and G. Szumanska (Akademiia Nauk Gruzinskoi SSR, Institut Fiziologii, Tiflis, Georgian SSR; Polish A82-21737 t Effect of low-temperature on the membrane Academy of Sciences, Experimental and Clinical Medicine Centre, permeability of erythrocytes reconstituted in media of different Warsaw, Poland). Biulleten''Eksperimental'noi Biologii i Meditsiny, ionic composition (Vliianie nizkotemperaturnogo vozdeistviia na vol. 91, Feb. 1981, p. 228-231. 9 refs. In Russian.

112 A82-21756

A82-21745 t A three-dimensional model for the arrange- ruiushchei radiatsii i tepla na protsess antiteloobrazovaniia). I. A. ment of the vascular and tubular components of the renal osmo- Gamzaeva, N. S. Gabai, R. F. lagubov, and D. Kh. Aivazova regulatory apparatus (Ob'emnaia model' zakladki sosudistogo i (Ministerstvo Zdravookhraneniia Azerbaidzhanskoi SSR, Respubli- kanal'tsevogo komponentov osmoreguliruiushchego apparata kanskii Nauchno-lssledovatel'skii Institut Virusologii, Mikrobiologii i pochki). V. I. Proniaev (Chernovitskii Meditsinskii Institut, Cher- Gigieny, Baku, Azerbaidzhan SSR). Gigiena i Sanitariia, Jan. 1981, p. novtsy, Ukrainian SSR). Biulleten' Eksperimental'noi Biologii i 35, 36. 8 refs. In Russian. Meditsiny, vol. 92, Aug. 1981, p. 114-116. 13 refs. In Russian. The responses of antibody formation processes to prolonged successive exposures to low doses of ionizing radiation and hyper- A82-21746 t Activation of the metabolism of the gamma- therm ia are investigated. Rats were exposed to a constant Co-60 aminobutyric acid system in the cerebral hemispheres under various gamma-ray source at dose rates of 0.0000305 to 0.0000292 A/kg for types of stress (Aktivatsiia metabolizma GAMK-sistemy v polu- 7 hours daily, temperatures of 40 C for 4 hours daily or radiation shariiakh golovnogo mozga pri deistvii razlichnykh stressornykh followed by heat for the course of 1 month, following which the faktorov). f. Z. Meerson, V. I. Pavlova, V. S. lakushev, and S. P. numbers of antibody forming cells in the spleen were determined by Sinitsyn (Akademiia Meditsinskikh Nauk SSSR, Moscow; Chelia- the method of lerne and Nordin (1963). Prolonged exposure to binskii Pedagogicheskii Institut; Cheliabinskii Meditsinskii Institut, radiation is found to lead to an 18.3% reduction in the number of Chelyabinsk, USSR). Biulleten' Eksperimental'noi Biologii i Me- antibody-forming cells, while hyperthermia has little influence on ditsiny, vol. 91, Jan. 1981, p. 23, 24. 10 refs. In Russian. antibody production in unirradiated animals. Successive exposure to The activation of the gamma-aminobutyric acid system's metab- both radiation and heat is observed to result in an even more olism is thought to occur through a nonspecific mechanism which pronounced suppression of antibody-forming cell production in the responds to a variety of extreme irritants. By limiting the stress spleen. A.L.W. syndrome, the mechanism prevents harmful effects. To test this hypothesis, the main parameters of the gamma-aminobutyric acid A82-21752 t The effects of elevated environmental tem- system are compared in four groups of animals. It is found that perature combined with radiation on the organism (Deistvie povy- activation can be brought about by an extremely wide range of shennoi temperatury okruzhaiushchei sredy v sochetanii s radiatsion- irritants. C.R. nym faktorom na organizm). M. M. Tsapkov. Gigiena i Sanitariia, Jan. 1981, p. 50-53. 24 refs. In Russian. Literature data concerning the combined effects of ionizing A82-21747 t Noise and vibration effects on vestibular and radiation and elevated temperatures on the physiological functions of visual functions in teenagers (Shumovibratsionnye vozdeistviia na laboratory animals is reviewed. The data demonstrate effects of vestibuliarno-zritel'nye funktsii u podrostkov). Ts. Popivanova combined exposures on the cardiovascular system, impairments in (Meditsinska Akademiia, Sofia, Bulgaria). Gigiena i Sanitariia, Sept. the enzymatic activity of various tissues and the inactivation of 1981, p. 58, 59. In Russian. chromosomal repair processes following radiation damage. The The purpose is to assess the effects of noise and vibration on the degree of radiation damage depends both on the radiation dose and activity of the vestibular and visual analyzers of teenagers receiving the duration of the temperature factor, although elevated tempera- training in the textile and machine-building industries. Special tures accelerate the elimination of radioactive substance from the attention is given to the vestibular effect on the visual system when body. A need for further experimental data for the evaluation of the vestibular analyzer is in a noninertial state. It is found that these human working conditions and radiation safety is expressed. A.L.W. teenagers are more susceptible, in terms of both frequency and severity, to impaired spatial perception. These disorders are found to A82-21753 t Echoencephalographic indices in patients with be independent of the amount of attention paid to the task at hand. hypertensive disease under the effect of functional loads C.R. (Ekhoentsefalograficheskie pokazateli u bol'nykh gipertonicheskoi bolezn'iu pod vliianiem funktsional'nykh nagruzok). lu. S. Gaiduk A82-21748 t Complex physiological-hygienic characteristics (Ukrainskii Nauchno-lssledovatel'skii Institut Kardiologii, Kiev, of a new work-rest regime for seamen (K kompleksnoi fiziologo- Ukrainian SSR). Vrachebnoe Delo, June 1981, p. 56-58. 8 refs. In gigienicheskoi kharakteristike novogo rezhima truda i otdykha Russian. plavsostava). lu. M. Sten'ko, D. S. Slutsker, L. M. Shafran, and V. N. Evstaf'ev (Ministerstvo Zdravookhraneniia SSSR, Nauchno- A82-21754 t Phasic energy analysis of rheoencephalograms Issledovatel'skii Institut Gigieny Vodnogo Transporta, Moscow, in the detection of the decompensation of cerebral hemodynamics USSR). Gigiena i Sanitariia, Jan. 1981, p. 27-29. In Russian. (Fazovo-energeticheskii analiz reoentsefalogramm pri raspoznavanii dekompensatsii tserebral'noi gemodinamiki). 0. N. Keller (Zapo- A82-21749 t Physiological-hygienic substantiation of admis- rozhskaia Oblastnaia Klinicheskaia Bol'nitsa, Zaporozhe, Ukrainian sible noise level in school rooms in a hot climate (Fiziologo- SSR) and I. la. Eingorn (Proizvodstvennoe Ob'edinenie Zaporozh- gigienicheskoe obosnovanie dopustimogo urovnia shuma v ucheb- transformator, Zaporozhe, Ukrainian SSR). Vrachebnoe Delo, Mar. nykh pomeshcheniiakh shkol i vuzov v usloviiakh zharkogo klimata). 1981, p. 99-102. 5 refs. In Russian. M. P. Magai (Uzbeksii Nauchno-lssledovatel'skii Institut Sanitarii, Gigieny i Profzabolevanii, Tashkent, Uzbek SSR) and I. L. Karago- dina (Moskovskii Nauchno-lssledovatel'skii Institut Gigieny, Moscow, A82-21755 t Clinical results on thymectomy in patients USSR). Gigiena i Sanitariia, Mar. 1981, p. 26-28. 12 refs. In Russian. with myopathy in relation to the degree of muscular weakness (Klinicheskie rezul'taty timektomii u bol'nykh miopatiei v zavisimosti ot stepeni myshechnoi slabosti). T. A. Valikova (Tomskii A82-21750 t Summary of a discussion on the problem of Meditsinskii Institut, Tomsk, USSR). Vrachebnoe Delo, May 1981, the 'biological norm' /in relation to an assessment of criteria of the p. 89-92. 6 refs. In Russian. harmfulness of chemical effects/ (Itogi diskussii po probleme 'biologicheskaia norma' /k otsenke kriteriev vrednosti khimicheskikh vozdeistvii/). I. M. Trakhtenberg and M. N. Korshun (Ministerstvo A82-21756 t Mechanisms of compensation and adaptation Zdravookhraneniia Ukrainskoi SSR, Nauchno-lssledovatel'skii Insti- in relation to the hyperfunction of the heart (Mekhanizmy kompen-. tut Gigieny Truda i Profzabolevanii, Kiev, Ukrainian SSR). Gigiena i satsii i adaptatsii pri giperfunktsii serdtsa). V. N. Dziak and S. F. Sanitariia, May 1981, p. 49-52. 21 refs. In Russian. Valevskii (Dnepropetrovskii Meditsinskii Institut, Dnepropetrovsk, The concept of the biological norm is discussed in relation to Ukrainian SSR). Vrachebnoe Delo, Mar. 1981, p. 88-92. 9 refs. In criteria of harmfulness in hygiene and toxicology. Ways of deter- Russian. mining this norm are considered, and particular attention is given to Results of a study of 167 patients with ischemic heart disease the development of quantitative and qualitative criteria of the are presented. It is found that, under conditions of urgent adaptation harmfulness of chemical (and other pollution-related) effects on the to physical stress, a process of latent decomposition occurs during organism. B.J. the early preclinical stage of cardiac insufficiency. This stage is characterized by a reduction of the diastolic relaxation rate of the A82-21751 t The effects of successive ionizing radiation and heart, a reduction of ejection fractions, stroke volume, and oxygen heat on antibody formation (Posledovatel'noe deistvie ionizi- pulse, and an increase in terminal diastolic and systolic volume. B.J.

113 A82-21757

A82-21757 t The effect of physical training on the lipid and kruglosutochnom ogranichenii podvizhnosti). M. K. Karimov lipoprotein metabolism in people of various ages (Vliianie fizicheskoi (Tadzhikskii Gosudarstvennyi Meditsinskii Institut, Dyushambe, Tad- trenirovki na obmen lipidov i lipoproteidov u liudei raznogo zhik SSR). Arkhiv Anatomii, Gistologii i Embriologii, vol. 81, Aug. vozrasta). S. V. Gogush, P. P. Chaialo, T. A. Kirienko, L. V. 1981, p. 82-86. 9 refs. In Russian. Riabokon' (Kievskii Nauchno-lssledovatel'skii Institut Meditsinskikh Various histological and morphometric methods were used to Problem Fizicheskoi Kul'tury, Kiev, Ukrainian SSR; Akademiia study vascular and tissue structures in the lungs of 49 dogs whose Meditsinskikh IMauk SSSR, Moscow, USSR), and V. P. Perfilov. movement was completely restricted for 1, 3, 7, 15, 30, 60, and 90 Vrachebnoe Delo, Sept. 1981, p. 51-53. 9 refs. In Russian. days. In nearly every period of the experiment, edema was found in the bronchial wall, perivsal and peribronchial tissue, and interalveolar septa. As the time of hypokinesia increases, the connective tissue A82-21758 t Metabolic change in test animals as an indi- becomes coarse and the collagenous fiber fasciculi become thicker cator of the biological effect of an electromagnetic field having a along the vascular bed. All the components are subject to mor- frequency of 50 Hz (Izmenenie metabolizma v organizme podopyt- phological alterations due to hypokinesia, which in turn affects the nykh zhivotnykh kak odin iz pokazatelei biologicheskogo deistviia gas-exchange function. B.J. EMP chastotoi 50 GTs). L. A. Tomashevskaia and lu. D. Dumanskii (Kievskii Nauchno-lssledovatel'skii Institut Obshchei i Kommunal'- A82-21766 t Age morphofunctional characteristics of chro- noi Gigieny, Kiev, Ukrainian SSR). Vrachebnoe Delo, July 1981, p. maffin tissue in the celiac nodes, both in the norm and with 98-100. In Russian. hypokinesia (Vozrastnaia morfofunktsional'naia kharakteristika khromaffinnoi tkani chrevnykh uzlov v norme i pri gipokinezii). S. A82-21759 t Certain features of cerebral hemodynamics in A. Kakabadze (Severo-Osetinskii Meditsinskii Institut, doing mental work at different air temperatures (Nekotorye osoben- Ordzhonikidze, USSR). Arkhiv Anatomii, Gistologii i Embriologii, nosti tserebral'noi gemodmamiki pri vypolnenii umstvennoi raboty v vol. 81, Aug. 1981, p. 57-64. 14 refs. In Russian. usloviiakh razlichnykh temperatur vozdukha). A. A. Lashchuk (Kievskii Nauchno-lssledovatel'skii Institut Gigieny Truda i Profza- A82-21767 t Features of the reaction to noise of the spinal bolevanii, Kiev, Ukrainian SSR). Vrachebnoe Delo, Aug. 1981, p. capillaries of white rats (Osobennosti reaktsii krovenosnykh kapil- 102-104. 8 refs. In Russian. liarov spinnogo mozga beloi krysy pri vozdeistvii shuma). G. A. Ivanenko (Khabarovsk!) Gosudarstvennyi Meditsinskii Institut, Kha- A82-21760 t The physical activity of humans as a social and barovsk, Ukrainian SSR). Arkhiv Anatomii, Gistologii i Embriologii, biological problem (Fenomen fizicheskoi aktivnosti cheloveka kak vol. 81, July 1981, p. 54-58. 5 refs. In Russian. sotsial'nc-biologicheskaia problema). V. K. Bal'sevich. Voprosy Filosofii, no. 8, 1981, p. 78-89. 18 refs. In Russian. A82-21768 t The source of reparative regeneration in skeletal muscle tissue (Ob istochnike reparatiunoi regeneratsii skelet- A82-21761 t Changes in the structure and cellular composi- nomyshechnoi tkani). A. A. Klishov and V. N. Vinogradova tion of the inguinal lymph nodes of white rats subjected to static and (Voenno-Meditsinskaia Akademiia, Leningrad, USSR). Arkhiv Ana- dynamic stresses (Izmenenie struktury i kletochnogo sostava pakho- tomii, Gistologii i Embriologii, vol. 81, Aug. 1981, p. 72-77. 16 refs. vykh limfaticheskikh uzlov belykh krys pod vliianiem dinamicheskoi In Russian. i staticheskoi nagruzok). T. I. Bikhruk (Leningradskii Institut Experiments were performed on 30 white rats to investigate the Fizicheskoi Kul'tury, Leningrad; Akademiia Meditsinskikh Nauk source of reparative regeneration in skeletal muscle tissue. Anterior SSSR, Moscow, USSR). Arkhiv Anatomii, Gistologii i Embriologii, tibial muscle was cut open and studied using light and electron vol. 80, May 1981, p. 23-29. 7 refs. In Russian. microscopy. The source of regeneration was found to be type I satellite cells which are transformed into type II satellite cells and, A82-21762 t Decussations in the human muscular system further, into myoblasts. These myoblasts are able to divide mytoti- (Perekresty v myshechnoi sisteme cheloveka). P. M. Petrova and G. cally and fuse with each other, forming myosymplasts. B.J. D. Keis (Minskii Meditsinskii Institut, Minsk, Belorussian SSR). A82-21769 t Neuronal-glial alterations in the cerebral cor- Arkhiv Anatomii, Gistologii i Embriologii, vol. 80, Apr. 1981, p. tex of animals under the influence of white noise (Neirono-glial'nye 32-38. 11 refs. In Russian. izmeneniia v kore bol'shogo mozga zhivotnykh pri vozdeistvii belogo A classification is presented which divides decussations of the shuma). N. I. Artiukhina, K. K. Hecht, I. P. Levshina, and 0. F. human muscular system into three groups: (1) decussations of Kubaeva (Akademiia Nauk SSSR, Institut Vysshei Nervnoi Deiatel'- muscles situated in neighboring layers of the same topographic area; nosti i Neirofiziologii, Moscow, USSR; Berlin, Humboldt-Universitat, (2) decussations of muscle-synergists; and (3) decussations of fibers Berlin, East Germany). Arkhiv Anatomii, Gistologii i Embriologii, of one muscle as well as of tendons of one muscle. It is proposed that vol. 81, Sept. 1981, p. 27-33. 20 refs. In Russian. decussation in a particular muscle group always presupposes decussation in the antagonistic group. The conformity of decussations in antagonistic groups of muscles is morphological evidence of their A82-21770 t Lysosomes under conditions of stress (Lizo- functional unity. B.J. somy v usloviiakh stressa). N. N. Maianskaia and L. E. Panin (Akademiia Meditsinskikh Nauk SSSR, Novosibirsk, USSR). Uspekhi A82-21763 t Dynamics of the condition of granulation Sovremennoi Bio/ogii, vol. 92, July-Aug. 1981, p. 64-80. 161 refs. In tissue after injuries sustained at different times of the day (Dinamika Russian. sostoianiia granuliatsionnoi tkani posle travmy, nanesennoi v raznoe Changes in the characteristics of lysosomes under conditions of vremia sutok). Kh. M. A. Marrades and L. P. Sapozhnikova (I stress are reviewed in relation to the role of lysosomes in stress Leningradskii Meditsinskii Institut, Leningrad, USSR). Arkhiv Ana- adaptation. Experimental data demonstrating changes in lysosome tomii; Gistologii i Embriologii, vol. 81, Oct. 1981, p. 47-51. 27 refs. enzyme activities, membrane permeability, numbers, sizes and In Russian. cellular locations upon organism exposure to stress factors including cooling, physical exercise, hypoxia, ionizing radiation, hyperbaric oxygenation, nutritional insufficiencies and altitude hypoxia training A82-21764 t An electron microscope study of hyperplasia is presented, and the hormonal regulation of lysosomal functions in fibers of the skeletal muscles of athletes (Elektronno- under stressful conditions is discussed. The role of the lysosome in mikroskopicheskoe issledovanie proiavlenii giperplazii myshechnykh adaptive responses to subextremal and extremal environmental volokon skeletnykh myshts sportsmenov). V. F. Kondalenko, lu. P. factors is then considered in the areas of metabolic adjustment, the Sergeev, and V. V. Ivanitskaia (Vsesoiuznyi Nauchno-lssledovatel'skii provision of cells with energy and material substrates, intracellular Institut Fizicheskoi Kul'tury, Moscow, USSR). Arkhiv Anatomii, regeneration, proliferative processes and stromal-parenchymal inter- Gistologii i Embriologii, vol. 80, June 1981, p. 66-70. 15 refs. In actions. A. L.W. Russian. A82-21771 t The state of the vegetative functions during A82-21765 t The morphology of the lungs of dogs whose sleep (Sostoianie vegetativnykh funktsii vo vremia sna). N. A. Vlasov movement is completely restricted (Morfologiia legkikh sobak pri (I Moskovskii Meditsinskii Institut, Moscow, USSR). UspekhiSoure-

114 A82-21781 me/mo/ Biologii, vol. 92, July-Aug. 1981, p. 127-139. 158 refs. In A82-21777 t The effect of piracetam on the body's resis- Russian. tance to hypoxia (Vliianie piratsetama na ustoichivost' organizma k Recent studies on vegetative functions and the dynamics of their gipoksii). L. F. Roshchina (Vsesoiuznyi Nauchno-lssledovatel'skii changes during various stages of night sleep are reviewed. Particular Khimiko-Farmatsevticheskii Institut, Moscow, USSR) and R. U. attention is given to the vegetative regulation during sleep of the Ostrovskaia (Akademiia Meditsinskikh Nauk SSSR, Moscow, USSR). cardiovascular, respiratory, and gastrointestinal systems, brain and Farmakologiia i Toksikologiia. vol. 44, Mar.-Apr. 1981, p. 210-213. skin temperature, electrodermal resistance, and the cutaneogalvanic 16 refs. In Russian. reflex. B.J. Experiments show that piracetam increases the resistance of animals to various types of hypoxia: hypoxic in mice and cats, A82-21772 t Nucleic acid and protein metabolism in cardiac circulatory in rats, and histotoxic in cats. But the drug does not exert muscle (Metabolizm nukleinovykh kislot i belkov v serdechnoi protective action in cats, rats, and mice with hemic hypoxia induced myshtse). M. P. lavich (Akademiia Meditsinskikh Nauk SSSR, by the injection of sodium nitrite. B.J. Moscow, USSR). Uspekhi Sovremennoi Biologii, vol. 91, May-June 1981, p. 334-349. 141 refs. In Russian. A82-21778 t Effects of dioxalim and oxamide on succinate and lactate dehydrogenase activities in rat liver, kidney and brain A82-21773 t Cellular and molecular bases of local immunity tissues and on the chromosomal apparatus of bone marrow cells (Kletochnye i molekuliarnye osnovy mestnogo immuniteta). A. E. (Vliianie dioksalima i oksamida na aktivnost' suktsinat- i laktatdegi- Vershigora and V. V. Ovod (Kievskii Gosudarstvennyi Universitet, drogenazy v tkaniakh pecheni, pochek, golovnogo mozga i na Kiev, Ukrainian SSR). Uspekhi Sovremennoi Biologii, vol. 91, khromosomnyi apparat kletok kostnogo mozga krys). I. P. Fo- May-June 1981, p. 393-408. 163 refs. In Russian. mochkin, A. I. Beketov, G. T. Pis'ko, I. R. Bariliak, IM. P. Barsukov, Experimental investigations of the last five years concerned with V. I. Bondarenko, G. F. Gusev, V. B. Levandovskii, T. G. the mechanisms of cellular and humoral immunity are reviewed with Prokopenko, and V. V. Svistov (Krymskii Meditsinskii Institut, particular emphasis on the local immunity of the mucous mem- Simferopol, Ukrainian SSR). Farmakologiia i Toksikologiia, vol. 44, branes. The origin, antigen induction and migration pathways of the Mar.-Apr. 1981, p. 611-616. 9 refs. In Russian. cells synthesizing class A immunoglobulins (IgA) are examined. Mechanisms controlling the relative populations of the plasmacytes A82-21779 t The effect of the prolonged administration of synthesizing IgA in the lymphoid formations associated with the sodium hydroxybutyrate on the physical work capacity and muscle mucous membranes and exocrine glands and the differentiation of tissue state of rats (Vliianie natriia oksibutirata pri prodolznitel'nom cells producing IgA dimers are discussed. Attention is also given to wedenii na fizicheskuiu rabotosposornost' i sostoianie myshechnoi results of studies of the integration of separate polypeptides, the tkani u krys). R. U. Ostrovskaia, N. N. Kleimenova, and V. A. physical and chemical properties of secretory molecules IgA, and Arefolov (Akademiia Meditsinskikh Nauk SSSR, Moscow, USSR). mechanisms of IgA dimer transport through the granular epithelium. Farmakologiia i Toksikologiia, vol. 44, Sept.-Oct. 1981, p. 534-539. A.L.W. 13 refs. In Russian. Experiments on albino rats involving the administration of A82-21774 t Mechanisms for the regulation of the intracel- sodium hydroxybutyrate for a two-month period (100 and 1000 lular calcium distribution (Mekhanizmy reguliatsii vnutrikletochnogo mg/kg daily) are described. It is found that such administration raspredeleniia kal'tsiia). S. N. Orlov (Ministerstvo Zdravookhraneniia increased the work capacity and body weight of the rats and SSR, IV Glavnoe Upravlenie - Tsentral'naia Nauchno- produced marked changes in the mitochondrial apparatus of cardiac Issledovatel'skaia Laboratoriia, Moscow, USSR). Uspekhi Sovremen- myocytes and skeletal muscles. Prolonged administration of the drug noi Biologii, vol. 92, July-Aug. 1981, p. 19-34. 151 refs. In Russian. resulted in an increased amount of mitochondria, polyploidy of Mechanisms involved in the hormonal and ionic regulation of cardiomyocyte nuclei (for a dose of 100 mg/kg) and marked cellular calcium levels and calcium binding by the various cellular hypertrophy (for a dose of 1000 mg/kg). It is suggested that this membranes are reviewed. Consideration is given to the regulation of drug has a specific anabolic effect based on hormonal control and an the calcium intake through changes in the potential-dependent and effect on protein synthesis. B.J. potential-independent membrane channels and the channels controlling sodium intake, and of calcium outflow through Ca-Na exchange A82-21780 t Adaptogenic effect of mebicar during emo- and Ca-ATPase which serve to maintain cellular calcium levels an tional stress, exercise, and hypoxia (Adaptogennyi effekt mebikara order of magnitude lower than those of the extracellular fluid. Also pri emotsional'nom napriazhenii, fizicheskoi nagruzke i gipoksii). M. examined are the kinetics of calcium bonding to the interior plasma M. Kozlovskaia, R. U. Ostrovskaia, N. N. Kleimenova, V. A. membrance, mitochondria and the endoplasmic reticulum. A.L.W. Kamysheva, and S. N. Sudareva (Akademiia Meditsinskikh Nauk SSSR, Moscow, USSR). Farmakologiia i Toksikologiia, vol. 44, A82-21775 t The application of bicycle ergometry to the Nov.-Dec. 1981, p. 654-657. 13 refs. In Russian. early detection of ischemic heart disease (0 primenenii veloer- Experiments on cats, mice, and rats disclosed the adaptogenic gometrii dlia rannego vyiavleniia ishemicheskoi bolezni serdtsa). V. effect of mebicar. The drug decreased emotional stress and removed la, Grigorov, E. G. Tarasik, and L. V. Mel'nikova. Voenno- the stupor-like state in cats induced by stress and pain stimulation. Meditsinskii Zhurnal, Aug. 1981, p. 56, 57. In Russian. The drug slightly increased the life span of animals under hypoxic A clinical study on the application of exercise cardiography to hypoxia and raised the limits of maximum tolerable physical load. It the detection of latent ischemic heart disease in apparently healthy reduced the accumulation of hypoxic lactate, and produced an persons is presented. The study involved the measurement of three- increase in glycogen content in muscle cells of the myocardium and and six-channel EKGs in 400 subjects undergoing submaximal skeletal muscles. B.J. bicycle ergometer exercise. Indicators of coronary insufficiency were found in 17.8% of persons considered to be practically healthy, A82-21781 t The effect of cholinomimetics on the develop- 66.2% of persons considered to be at high risk for ischemic heart ment of hypothermia (Vliianie kholinomimetikov na skorost' razvi- disease, 56.4% of persons with unusual resting EKGs characteristics tiia gipotermii). N. 0. Bazhanov and V. N. Saliaev (laroslavskii of ischemia and 46.1% of persons with cardialgia. Results thus Meditsinskii Institut, Yaroslavl, USSR). Farmakologiia i Toksikolo- demonstrate the usefulness of exercise cardiography in clinical giia, vol. 44, Jan.-Feb. 1981, p. 40-43. 8 refs. In Russian. situations for the detection of latent ischemic heart disease in Experiments were performed on 120 male rats to study the rate otherwise healthy persons or persons at high risk undergoing close of hypothermia development in different stages: mild, medium, and medical surveillance. A.L.W. deep; corresponding to rectal temperatures of 33, 26, and 19 C. This rate decreased significantly in mild hypothermia induced by nicotine A82-21776 t Effects of pyrroxane and methylapogalanta- (4 mg/kg), in medium hypothermia induced by nicotine and mjne on cerebral blood circulation and oxygen regime (Vliianie pilocarpine (25 mg/kg), and methacine (20 mg/kg) combined with pirroksana i metilapogalantamina na krovoobrashchenie i kislorodnyi arecoline (20 mg/kg), and in deep hypothermia induced by metha- rezhim golovnogo mozga). V. E. Pogorelyi (Piatigorskii Farmatsev- cine combined with arecoline. However, the rate of development was ticheskii Institut, Pyatigorsk, USSR). Farmakologiia i Toksikologiia, found to rise in deep hypothermia induced by methacine (20 mg/kg) vol.44, Mar.-Apr. 1981, p.167-170. 14 refs. In Russian. combined with proserine (0.45 mg/kg). B.J.

115 A82-21782

A82-21782 t The infrastructure of the liver sinusoids of The effect of prolonged light stimulation on different parts of mice under conditions of acute stress • Morphometric study the visual analyzer was investigated in cats. The adaptation process (Ul'trastruktura sinusoidov pecheni myshei v usloviiakh ostrogo was found to be very complex as manifested in the diverse parallel stressa - Morfometricheskoe issledovanie). V. A. Shkurupii (Novosi- processes in the hierarchic structure of the analyzer. Adaptive birskii Meditsinskii Institut, Novosibirsk, USSR). Tsito/ogiia i Geneti- reorganization in the distal parts of the retina is directed towards the ka, vol. 15, May-June 1981, p. 3-8. 8 refs. In Russian. regulation of general sensitivity, while in the optic channel and An analysis is presented of structural changes in the endothelial lateral geniculate body this reorganization is directed towards the and Kupffer liver cells of male mice after acute physical stress. It is reduction of the dependence of cortical process on fluctuations of found that these changes are evidence of the intensification of the illumination level. The predominance of inhibitory processes in endocytose processes and the inhibition of protein synthesis. B.J. the cortex characterizes the increasing complexity of cortical processes. It is also shown that the reorganization of electrical activity expresses not only a change of sensitivity but also adaptation A82-21783 t The existence of an endogenous biorhythm in to many parameters which characterize the transition from darkness chromatin-positive cells of the buccal epithelium in women (0 to light. B.J. sushchestvovanii endogennogo bioritma khromatinpolozhitel'nykh kletok bukkal'nogo epiteliia zhenshchin). T. A. Zaletaeva and lu. E. A82-21789 t Types of spontaneous discharges in muscle Ershikova (Tsentral'nyi Institut Usovershenstvovaniia Vrachei, Mos- receptors (Tipy spontannykh razriadov myshechnykh retseptorov). cow, USSR). Tsito/ogiia i Genetika, vol. 15, July-Aug. 1981, p. 7-9. V. I. Zalkind (Akademiia Nauk SSSR, Institut Fiziologii, Leningrad, 14 refs. In Russian. USSR). Neirofiziologiia, vol. 13, no. 3, 1981, p. 315-321. 12 refs. In Russian. A82-21784 t EEG evaluation of mental stress (K EEG- Based on an analysis of spontaneous and induced discharges otsenke umstvennogo napriazheniia). I. M. Volkova and S. I. from the receptors of passive m. triceps muscle spindles in cats, three Gorshkov (Akademiia Meditsinskikh Nauk SSSR, Moscow, USSR). types of responses have been identified: (1) continuous pulse train Zhurnal Vysshei Nervnoi Deiatel'nosti, vol. 31, Sept.-0ct. 1981, p. with unimodal symmetric intervals between pulses; (2) bunched 1071-1075. 7 refs. In Russian. action potentials with bimodal interval distribution; and (3) sporadic The paper reviews several EEG studies of mental stress and pulses with long intervals between pulses. Comparison of the mental work capacity involving visual search. The search perfor- characteristics of spontaneous discharges and discharges induced by mance was studied as a function of the duration of the preparation static muscle stretching indicates that both types of responses have period, and the electrophysiological correlates of this search activity the same mechanism. It is suggested that spontaneous activity may were investigated along with its efficiency, the state of preparedness, be viewed as a static response of receptors to internal factors related and the associated intercentral relations. B.J. to interaction between extrafusal and intrafusal muscular fibers. V. L A82-21790 t Comparative neurophysiological characteristics A82-21785 t The effects of emotional activation on the of cold and caudate tremors (Sravnitel'naia neirofiziologicheskaia spatial synchronization of human brain biopotentials (Vliianie kharakteristika kholodovogo i kaudatnogo tremora). lu. V. Lupandin emotsional'noi aktivatsii na prostranstvennuiu sinkhronizatsiiu bio- (Petrozavodskii Gosudarstvennyi Universitet, Petrozavodsk, USSR). potentsialov golovnogo mozga cheloveka). M. N. Rusalova (Akade- Neirofiziologiia, vol. 13, no. 3, 1981, p. 257-263. 21 refs. In Russian. miia Nauk SSSR, Institut Vysshei Nervnoi Deiatel'nosti i Neirofizio- In experiments carried out on cats, comparisons are made logii, Moscow, USSR). Zhurnal Vysshei Nervnoi Deiatel'nosti, vol. between two models of postural tremor, one induced by exposure to 31, Mar.-Apr. 1981, p. 403-405. 9 refs. In Russian. cold, the other by an injection of oxotremorine into the caudate nucleus. The electromyograms of both models are identical; the frequency of activity of the motor units, which operate independent- A82-21786 t Functional state of the hippocampal-reticular ly, is 4-12 pulses/sec. C.R. complex under submaximal physical load and fatigue (Funktsional'- noe sostoianie gippokampo-retikuliarnogo kompleksa pri submaksi- mal'noi fizicheskoi nagruzke i utomlenii). V. M. Boev (Orenburgskii A82-21791 t Poststimulatory auditory adaptation in Gosudarstvennyi Meditsinskii Institut, Orenburg, USSR) and V. A. humans according to computer audiometry (Poststimuliatsionnaia Krauz (Dnepropetrovsk ii Meditsinskii Institut, Dnepropetrovsk, slukhovaia adaptatsiia u cheloveka po dannym kompiuternoi audio- Ukrainian SSR). Zhurnal Vysshei Nervnoi Deiatel'nosti, vol. 31, metrii). B. M. Sagalovich and G. G. Melkumova (Ministerstvo Sept.-Oct. 1981, p. 1029-1037. 27 refs. In Russian. Zdravookhraneniia SSSR, Moskovskii Nauchno-lssledovatel'skii Insti- Results are presented on 22 rabbits with bipolar electrodes tut Ukha, Nosa i Gorla, Moscow, USSR). Vestnik Otorinolaringo- implanted in the dorsal hippocampus and the midbrain reticular logii, Mar.-Apr. 1981, p. 15-20. 27 refs. In Russian. formation. It is shown that a submaximal physical load in nontrained animals results in a stable reduction in the excitability of the structures studied. In the course of a 30-day training program, the A82-21792 t Cochlear analysis of sound intensity and some excitability of the hippocampus was reduced, while the excitability mechanisms of auditory sensations (Kokhlearnyi analiz sily zvuka na of the reticular formation underwent a short-term increase but then nekotorye mekhanizmy slukhovykh oshchushchenii). V. N. Akimov returned to the initial level on the 20th day of training. High- (Kazanskii Meditsinkii Institut, Kazan, USSR). Vestnik Otorinolarin- amplitude activity predominated in the EEG of the structures gologii, May-June 1981, p. 15-18. 21 refs. In Russian. studied, while local blood flow increased only in the reticular formation. B.J. A82-21793 t Methods for diagnosing hearing loss in workers A82-21787 t The relationship between cardiac and motor exposed to high noise levels in accordance with state standards components of a conditioned reflex upon the local cooling of various (Metody opredeleniia poter' slukha u rabochikh 'shumovykh' pro- zones of the cerebral cortex in cats (O sootnoshenii serdechnogo i fessii v sootvetstvii s gosudarstvennym standartom). V. E. Ostapko- dvigatel'nogo komponentov uslovnogo refleksa pri lokal'nom vich, G. A. Suvorov, L. N. Shkarinov, N. I. Ponomareva, and E. I. okhlazhdenii razlichnykh zon kory bol'shikh polusharii u koshek). E. Denisov (Akademiia Meditsinskikh Nauk SSSR, Moscow, USSR). M. Berdichevskaia, lu. M. Perov, and V. M. Pokrovskii (Kubanskii Vestnik Otorinolaringologii, July-Aug. 1981, p. 12-16. 5 refs. In Meditsinskii Institut, Krasnodar, USSR). Zhurnal Vysshei Nervnoi Russian. Deiatel'nosti, vol. 31, Jan.-Feb. 1981, p. 64-69. 23 refs. In Russian.

A82-21788 t Coordination of processes in the hierarchic A82-21794 t Hygienic standards for industrial noise structure of the visual analyzer (Koordinatsiia protsessov v ierar- (Gigienicheskoe normirovanie proizvodstvennogo shuma). G. A. khicheskoi strukture zritel'nogo analizatora). V. B. Val'tsev (Akade- Suvorov, L. N. Shkarinov, V. G. Ovakimov, and E. I. Denisov miia Nauk SSSR, Institut Vysshei Nervnoi Deiatel'nosti i Neirofizio- (Akademiia Meditsinskikh Nauk SSSR, Moscow, USSR). Akademiia logii, Moscow, USSR). Zhurnal Vysshei Nervnoi Deiatel'nosti, vol. Meditsinskikh Nauk SSSR, Vestnik, no. 1, 1981, p. 62-66. 10 refs. In 31, no. 3, 1981, p. 598-604. 21 refs. In Russian. Russian.

116 A82-21809

A82-21795 t A comparative evaluation of the hemodynamic at the moment when sharp changes in indicator gas concentration effects of large doses of morphine, dipidolor, pentazocine, and signal the onset of phase IV of the single breath curve, were obtained phentanyl (Sravnitel'naia otsenka gemodinamicheskikh effektov in 10 subjects with normal spirographic data by both oxygraphic and bol'shikh doz morfina, dipidolora, pentazotsina i fentanila). F. F. nitrographic techniques. A high degree of correlation between the Beloiartsev, B. I. Islamov, and V. G. Stranin (Akademiia Nauk SSSR, results of the techniques is found, indicating the oxygraphic method Institut Biologicheskoi Fiziki, Pushchino; Akademiia Meditsinskikh to be as useful as nitrography for the examination of the small IMauk SSSR, Moscow, USSR). Akademiia Meditsinskikh Nauk SSSR, respiratory ducts. In addition, the use of oxygen as a test gas Vestnik. no. 8, 1981, p. 22-28. 10 refs. In Russian. facilitates the detection of the inflection point in the single breath Four series of experiments are carried out on 84 mongrel dogs curve, increasing test accuracy. A. L.W. to study the effect of morphine (3 mg/kg), dipidolor (4.5 mg/kg), pentazocine (2.5 mg/kg), and phentanyl (0.0084 mg/kg) on systemic A82-27802 t Seasonal rhythm of the immune reactivity and and pulmonary hemodynamics, on myocardial contraction, and on heart tolerance to physical load in patients with ischemic heart coronary blood flow and microcirculation. It is found that in disease (Sezonnyi ritm tolerantnosti serdtsa k nagruzke i immunnoi contrast to general anesthetics, large doses of the narcotic analgesics reaktivnosti u bol'nykh ishemicheskoi bolezn'iu serdtsa). I. E. used clinically for anesthetic purposes in operations do not suppress Oranskii, V. P. Ditiatev, I. M. Kheinonen, I. S. Golod, and E. I. hemodynamics. C. R. Solov'eva (Sverdlovskii Nauchno-lssledovatel'skii Institut Kuror- tologii i Fizioterapii; Sverdlovskii Meditsinskii Institut, Sverdlovsk, A82-21796 t Emotional stress as a factor in cardiovascular USSR). Sovetskaia Meditsina, no. 7, 1981, p. 11-14. 9 refs. In disorders (Emotsional'nyi stress kak faktor serdechno-sosudistykh Russian. narushenii). K. V. Sudakov (Akademiia Meditsinskikh Nauk SSSR, Moscow, USSR). Akademiia Meditsinskikh Nauk SSSR, Vestnik, no. A82-21803 t Evaluation of the functional state of the 9, 1981, p. 10-18. 27 refs. In Russian. cardiovascular system in patients with ischemic heart disease with It is shown in experiments on animals that conflict can bring on reference to the nature of their occupational activity (Otsenka serious cardiovascular orders, including ischemia and myocardial funktsional'nogo sostoianiia serdechno - sosudistoi sistemy bol'nykh infarction. The roles played by limbic structures and by the reticular iskhemicheskoi bolezn'iu serdtsa v zavisimosti ot kharaktera ikh formation of the brain stem in mechanisms responsible for arterial trudovoi deiatel'nosti). B. M. Kogan, L. E. Kuz'mishin, D. I. Lavrova, hypertension and disturbances in cardiac activity in times of D. A. Sokolova, and 0. S. Andreeva (Tsentral'nyi Nauchno- emotional stress are established. Genetic characteristics of resistance lssledovatel'skii Institut Ekspertizy Trudosposobnosti i Organizatsii and of predisposition to stress-induced cardiovascular disorders are Truda Invalidov, Moscow, USSR). Sovetskaia Meditsina, no. 8, 1981, identified. Attention is also given to the distribution of cate- p. 9-13. 13 refs. In Russian. cholamines in the brain stem structures of the animals that are either resistant or predisposed to these disorders. C. R. A82-21804 t Emotions, sleep, and health (Emotsii, son i zdorov'e). V. Rotenberg (I Moskovskii Meditsinskii Institut, Moscow, A82-21797 t Computer-aided analysis of the effect of the USSR). Nauka iZhizn', Aug. 1981, p. 86-91. In Russian. initial narcosis on the central hemodynamics (Komp'iuternyi analiz The paper reviews some of the topics discussed at the Baku vliianiia razlichnykh variantov vvodnogo narkoza na tsentral'nuiu symposium (held in October 1981) on search performance, motiva- gemodinamiku). A. A. Buniatian, M. N. Seleznev, E. V. Flerov, G. I. tion, and sleep. Particular consideration is given to harmful types of Kalina, and la. A. Solomka (Ministerstvo Zdravookhraneniia SSSR, stress and the protective function of sleep. B.J. Vsesoiuznyi Nauchnyi Tsentr Khirurgii, Moscow, USSR). Akademiia Meditsinskikh Nauk SSSR, Vestnik, no. 8, 1981, p. 33-40. 20 refs. In A82-21805 t Physical health of truck drivers in the open-pit Russian. mining industry of the far north (Sostoianie zdorov'ia voditelei avtotransporta kar'erov dobyvaiushchei promyshlennosti Krainego Several. G. N. German (lakutskii Gosudarstvennyi Universitet, A82-21798 t LDH isoenzyme spectrum in intact and dener- Yakutsk, USSR). Zdravookhranenie Rossiiskoi Federatsii, no. 9, vated skeletal muscles of rats of various age during cold adaptation 1981, p. 14, 15. In Russian. (Izofermentnyi spektr LDG v intaktnykh i denervirovannykh skeletnykh myshtsakh krys razlichnogo vozrasta pri adaptatsii k kholodu). A82-21806 t A study of tropomyosins in human muscular L. F. Shcherbak (Kievskii Meditsinskii Institut, Kiev, Ukrainian and nonmuscular organs (Izuchenie tropomiozinov myshechnykh i SSR). Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia, nemyshechnykh organov cheloveka). A. A. Davydov, G. F. Sycheva, Jan.-Feb. 1981, p. 69-72. 5 refs. In Russian. and A. B. Zborovskii (Volgogradskii Meditsinskii Institut, Volgograd, USSR). Voprosy Meditsinskoi Khimii, vol. 27, May-June 1981, p. A82-21799 t The role of urokinase in the regulation of the 330-334. 15 refs. In Russian. fibrinolytic activity of blood under normal conditions (RoT uro- kinazy v reguliatsii fibrinoliticheskoi aktivnosti krovi v estestvennykh A82-21807 t The multiple forms of tyrosine amino- usloviiakh). V. I. Kuznik and D. V. Vasil'ev (Chitinskii Meditsinskii transferase in rat liver cells and their role in cellular homeostasis Institut, Chita, USSR). Patologicheskaia Fiziologiia i Eksperimental'- (Mnozhestvennye formy tirozinaminotransferazy v kletkakh pecheni naia Terapiia, May-June 1981, p. 45-47. 7 refs. In Russian. krys i ikh roT v gomeostaze kletki). N. P. Mertvetsov (Glavmikrobio- prom, Spetsial'noe Konstruktorsko-Tekhnologicheskoe Biuro Biolo- A82-21800 t The role of CO2 in the mechanism of the gicheski Aktivnykh Veshchestv, Novosibirsk, USSR). Voprosy reparative regeneration of bone tissue /a radioisotopic study/ (RoK Meditsinskoi Khimii, vol. 27, Mar.-Apr. 1981, p. 154-166. 57 refs. In C02 v mekhanizme reparativnoi regeneratsii kostnoi tkani /radio- Russian. izotopnoe issledovanie/). I. M. Dmitriev (Odesskii Meditsinskii Institut, Odessa, Ukrainian SSR) and lu. A. Petrovich (Moskovskii A82-21808 t The dynamics and physiological importance of Meditsinskii Stomatologicheskii Institut, Moscow, USSR). Patologi- the activation of the gamma-amino-butyric acid system in the brain cheskaia Fiziologiia i Eksperimental'naia Terapiia, May-June 1981, p. and cardiac muscle under pain and emotional stress (Dinamika i 28-32. 14 refs. In Russian. fiziologicheskoe znachenie aktivizatsii GAMK-sistemy v golovnom mozge i serdechnoi myshtse pri emotsional'no-bolevorn stresse). F. 7.. A82-21801 t The use of oxygen as the test gas in the Meerson (Akademiia Meditsinskikh Nauk SSSR, Moscow, USSR). R. determination of the closing volume of respiratory ducts (Primenenie I. Lifshits (Cheliabinskii Gosudarstvennyi Pedagogicheskii Institut, kisloroda kak test-gaza dlia opredeleniia ob'ema zakrytiia dykhatel'- Chelyabinsk, USSR), and V. I. Pavlova (Cheliabinskii Meditsinskii nykh putei). V. E. Bagdat'ev, V. I. Platonov, I. lu. Lapshina, and lu. Institut, Chelyabinsk, USSR). Voprosy Meditsinskoi Khimii, vol. 27, V. Andreev (II Moskovskii Meditsinskii Institut, Moscow, USSR). Jan.-Feb. 1981, p. 35-39. 7 refs. In Russian. Sovetskaia Meditsina, no. 5, 1981, p. 28-31. 13 refs. In Russian. The use of oxygen as the indicator gas in the determination of pulmonary closing volumes in the single breath expiration test is A82-21809 t Nonesterified fatty acid metabolism during investigated. Closing volumes, calculated as the volume of gas expired exercise in humans (Obmen neesterifitsirovannykh zhirnykh kislot

117 A82-21810

pri fizicheskikh nagruzkakh u cheloveka). S. P. Anikeeva and lu. M. Moscow, USSR). Teoriia i Praktika Fizicheskoi Ku/'tury, Aug. 1981, Shternberg (Gosudarstvennyi Tsentral'nyi Institut Fizicheskoi Kul'- p. 39, 40. In Russian. tury, Moscow, USSR). Voprosy Meditsinskoi Khimii, vol. 27, July-Aug. 1981, p. 435-441. 72 refs. In Russian. A82-21817 t Trial on the use of stabilography in the The characteristics of nonesterified fatty acid metabolism during medical supervision of boxers (Opyt ispol'zovaniia stabilografii v exercise and physical training in humans are discussed. The mobiliza- meditsinskom kontrole za bokserami). E. 6. Liubchinskii and R. Z. tion of nonesterified fatty acids due to the action of sympathetic Kravets (Orenburgskii Gosudarstvennyi Meditsinskii Institut, Oren- intermediaries during exercise is discussed, and the importance of the burg, USSR). Teoriia i Praktika Fizicheskoi Kul'tury, Aug. 1981, p. nonesterified fatty acids as an energy source is emphasized. Problems 23, 24. 13 refs. In Russian. in the understanding of the mechanisms by which physical training A clinical trial is presented on the application of stabilography increases the capability of the muscles to utilize nonesterified fatty to the detection and subsequent monitoring of vestibular impair- acids are examined, and it is pointed out that the degree of fatty acid ments resulting from cranio-cerebral trauma in boxers. Oscillations of mobilization is determined by the intensity of the exercise relative to subject center of gravity while standing in the Romberg position in maximal oxygen uptake. Data on the variations in plasma fatty acid the frontal and sagittal planes were measured in 112 subjects over the levels during work is reviewed, and the concepts of the plasma pool course of six years, with 27 serving as controls and 89 boxers having and its turnover rate are introduced as quantitative indicators of undergone head trauma as the result of a knockout. Measurements metabolic processes. Finally, attention is given to the factors made before and after injuries reveal the vestibular apparatuses of determining the transport, oxidation rate and de nova synthesis of boxers having had previous equilibrium training to be more resistant single fatty acids, carbon, and to changes in the quantitative and to athletic trauma, indicative of a need for the development of a qualitative characteristics of nonesterified fatty acid metabolism method for training the organs of equilibrium during the preparation upon the cessation of exercise. A.L.W. of a boxer. Head traumas are also found to be occasionally accompanied by evident and persistent disorders in static coordination. The method of stabilography is thus recommended for use in A82-21810 t Approaches to the removal of G2-chalone the medical supervision of boxers. A.L.W. from the liver of rats (Nekotorye podkhody k ochistke G2-khalona pecheni krys). V. M. Rodionov, N. A. Kuz'micheva, A. V. Pospelova, and M. V. Pleskova (Akademiia Meditsinskikh Nauk SSSR, Moscow, A82-21818 T Rationalizing physical regimen of sedentary USSR). Voprosy Meditsinskoi Khimii, vol. 27, July-Aug. 1981, p. workers (Obosnovanie ratsional'nogo dvigatel'nogo rezhima liuder 569-572. 15 refs. In Russian. umstvennogo truda). V. V. Mitrokhina (Moskovskii Tekhnologi- cheskii Institut Bytovogo Obsluzhivaniia Naseleniia RSFSR, Moscow, A82-21811 t The effects of daily blood sampling on USSR). Teoriia i Praktika Fizicheskoi Ku/'tury, Aug. 1981, p. 32-34. creatine phosphokinase, aspartate aminotransferase and alanine 8 refs. In Russian. aminotransferase activities in the blood serum of the monkey (Vliianie ezhednevnogo vziatiia krovi na aktivnost' kreatinfosfokina- A82-21819 t Effect of the functional properties of the zy, AST i ACT v syvorotke krovi obez'ian). N. E. Lemondshava and vestibular analyzer on the effectiveness of instruction in gymnastics Sh. L. Dzhalagoniia (Akademiia Meditsinskikh Nauk SSSR, Sukhumi, (Vliianie funktsional'nykh svoistv vestibuliarnogo analizatora na Georgian SSR). Voprosy Meditsinskoi Khimii, vol. 27, Jan.-Feb. effektivnost' obucheniia gimnasticheskim uprazhneniiam). A. I. 1981, p. 64-67. 11 refs. In Russian. Popugaev (Udmurtskii Gosudarstvennyi Universitet, Izhevsk, USSR). Teoriia i Praktika Fizicheskoi Kul'tury, Aug. 1981, p. 30, 31. 8 refs. A82-21812 t Temperature dependence of alanine and aspar- In Russian. tate aminotransferase activities in rat brain during hypothermia of various durations and adrenalectomy (Temperaturnaia zavisimost' A82-21820 t Mechanisms of adaptation to ergothermic aktivnosti alanin- i asparat-aminotransferaz v mozge krys pri gipoter- hypoxemia in athletes specializing in different sports (Mekhanizmy mii raznoi dlitel'nosti i pri adrenalektomii). T. N. Daudova, I. S. adaptatsii k ergotermicheskoi gipoksemii u sportsmenov razlichnykh Meilanov, and E. Z. Emirbekov (Dagestanskii Gosudarstvennyi spetsializatsii). V. A. Romanenko (Nauchno-lssledovatel'skii Institut Universitet, Makhachkala, USSR). Voprosy Meditsinskoi Khimii, vol. Gigieny Truda i Profzabolevanii, Donetsk, Ukrainian SSR). Teoriia i 27, May-June 1981, p. 359-362. 7 refs. In Russian. Praktika Fizicheskoi Kul'tury, Aug. 1981, p. 22, 23. 18 refs. In Russian. The effects of athletic training for speed, endurance or strength A82-21813 t Blood serum nuclease activity in healthy per- on physiological responses to hypoxemia resulting from physical sons and patients with various hematological diseases (Nukleaznaia exercise under thermal stress are investigated, along with the role of aktivnost' syvorotki krovi zdorovykh liudei i bol'nykh s nekotorymi these responses in establishing the elevated heat tolerance of athletes. gematologicheskimi zabolevaniiami). M. N. Blinov, I. S. Luganova, Measurements of heart rate, blood oxygenation, oxygen uptake, and and A. 0. Vladimirova (Leningradskii Nauchno-lssledovatel'skii respiratory minute volume and rate were made during ergometer Institut Gematologii i Perelivaniia Krovi, Leningrad, USSR). Voprosy exercise at an ambient temperature of 50 C and relative humidity of Meditsinskoi Khimii, vol. 27, Mar.-Apr. 1981, p. 211-215. 17 refs. In 50% in sprinters, distance runners and weightlifters, and a control Russian. group of students. Ergothermic stress is found to produce a less marked decrease in blood oxygenation in the athletes than in the A82-21814 t. Predicting the potentials of young swimmers controls which is associated with a hyperfunction of the oxygen based on clinical and physiological data (Prognozirovanie perspek- transport system in the weightlifters, and improvements in the tivnosti iunykh plovtsov s uchetom kliniko-fiziologicheskikh dan- mechanisms of oxygen utilization and transport in the runners. In nykh). I. P. Nikitin (Smolenskii Meditsinskii Institut, Smolensk, the sprinters, improved heat tolerance is related to mechanisms USSR). Teoriia iPraktika Fizicheskoi Ku/'tury, Sept. 1981, p. 22-24. counteracting the effects of ergothermic hypoxemia, while the 16 refs. In Russian. distance runners are better able to tolerate the hypoxemia. A.L.W. A82-21815 t The dynamics of heart rate recovery following A82-21821 t Stress and immunity in athletes (Stress i work of various aerobic intensities (Dinamika vosstanovleniia chastc- immunitet u sportsmenov). I. D. Surkina (Vsesoiuznyi Nauchno- ty serdechnykh sokrashchenii posle rabot raznoi aerobnoi moshch- lssledovatel'skii Institut Fizicheskoi Kul'tury, Moscow, USSR). nosti). V. M. Alekseev (Gosudarstvennyi Tsentral'nyi Institut Fizi- Teoriia i Praktika Fizicheskoi Kul'tury, Mar. 1981, p. 18-20. 9 refs. cheskoi Kul'tury, Moscow, USSR). Teoriia i Praktika Fizicheskoi In Russian. Ku/'tury, July 1981, p. 24-26. 11 refs. In Russian. The effects of the physical, and emotional stresses encountered during competition on the immune status of athletes are investigated. A82-21816 t Development of an automatic data bank for Experiments involving a functional test (maximal exercise) and managing physical education of students (Razrabotka avtomatiziro- evaluation of the levels and activities of T and B lymphocytes were vannogo banka dannykh dlia upravleniia fizicheskim vospitaniem performed on healthy young athletes from different sports during studentov). S. S. Prapor, I. G. Sokolov, V. A. Soldatov, A. L. competitive periods of various durations, at various stages of Galitskii, and R. M. Nosova (Moskovskii Institut Stali i Splavov, preparation and following the competitive seasons. Changes irt

118 A82-21929 immune processes, particularly the T system of immunity, were and sleep. Responses to auditory and visual stimuli, electrocar- observed in all types of sports and in all times of the year. The diograms, electrooculograms, electroencephalograms, as well as suppression of the immune reaction found under the influence of the evoked potentials and contingent negative variation were observed in training stresses in the preparatory period is observed to be transient, nurses immediately following work on the night shift or a night's and alternates with a recovery following rest. Changes in immunity sleep preceding work on the evening shift. The neurophysiological are indicative of a general adaptive stress syndrome resulting in an tests as well as the more routine techniques reveal a reduction in the exhaustion phase, which leads to an increased morbidity risk. general activity level in nurses foflowing the night shift, which is Immunological monitoring may thus be used to predict individual particularly evident as a reduction in attention. Results suggest the likelinesses of becoming ill, and to develop training schedules potential applications of the techniques employed in the establish- minimizing health risks. A.L.W. ment of optimal work-rest cycles. A.L.W.

A82-21822 t Radiometric determination of potassium con- A82-21893 t Mathematical model of a human operator tent in athletes (Radiometricheskoe opredelenie soderzhaniia kaliia v detecting a signal on a noise background (Matematicheskaia model' organizme sportsmenov). O. Z. Paikin, E. V. Ivanov, V. A. cheloveka-operatora, obnaruzhivaiushchego signal na fone shuma). N. Plakhtienko, and lu. N. Shishmarev (Voennyi Institut Fizicheskoi M. Novikova. Radioelektronika, vol. 25, Jan. 1982, p. 91-93. In Kul'tury, Leningrad, USSR). Teoriia i Praktika Fizicheskoi Kul'tury, Russian. July 1981, p. 26, 27. In Russian. In the problem considered, the human operator must detect a signal with an unknown arrival time on a background of Gaussian A82-21823 t Characteristics of the structure and functions noise. It is shown that the functioning of the operator can be of the middle ear of lizards (Osobennosti stroeniia i funktsii srednego described by a nonparametric sign detector model. The probability ukha iashcherits). S. V. Smirnov (Akademiia Nauk SSSR, Institut of correct detection is examined as a function of signal-to-noise ratio, Evoliutsionnoi Morfologii i Ekologii Zhivotnykh, Moscow, USSR). and the effectiveness of the model is confirmed by experimental Zhurnal Evoliutsionnoi Biokhimii i Fiziologii, vol. 17, July-Aug. results. B.J. 1981, p. 395-400. 14 refs. In Russian. A82-21926 An asymmetrical model of the airways of the A82-21824 t The mathematics of immunity (Matematika dog lung. K. Horsfield, W. Kemp, and S. Phillips (Midhurst Medical immuniteta). A. Galeva. Nauka i Zhizn', Mar. 1981, p. 66-74. In Research Institute, Midhurst, Sussex, England). Journal of Applied Russian. Physiology: Respiratory, Environmental and Exercise Physiology, The mathematical modeling of immune responses to a viral vol. 52, Jan. 1982, p. 21-26. 16 refs. intrusion is discussed. Following a review of the functions and major An asymmetrical model is developed for the branching of the components of the immune system and its interactions with the brachial tree in dog lung. The model is based on measurements made processes occurring during the course of a disease infection, a on a resin cast of the bronchial tree of a 25-kg dog, for which mathematical model of infection and immune responses to it is dimensions and branching relationships were obtained in branches presented which is formulated in terms of viral growth, the responses down to 0.5-mm diameter. The branches were ordered, the number of plasma cells and antibody production, and damage to the target in each order was counted, and the mean diameter and length in an organs. Possible applications of the model in clinical practice and to order was calculated. The model was then constructed according to the understanding of the nature of disease are then examined. A.L.W. delta, the difference in order between the two daughter branches at a bifurcation, with delta taken as identical for all parent branches of a given order. The model is thus especially useful for computer analysis A82-21825 t Acute experimental emotional stress in rabbits /physiological and cytochemical aspects/ (Ostryi eksperimental'nyi of such variables as input impedance. A.L.W/ emotsional'nyi stress u krolikov /fiziologo-tsitokhcmicheskie A82-21927 Increased excretion of urea and N/tauA aspekty/). A. V. Gorbunova, N. V. Petrova, V. V. Portugalov, and S. methylhistidine by rats and humans after a bout of exercise. G. L. K. Sudakov (Akademiia Meditsinskikh Nauk SSSR, Moscow, USSR). Dohm, R. T. Williams, G. J. Kasperek, and A. M. van Rij (East Akademiia Nauk SSSR. Izvestiia, Seriia Biologicheskaia, Jan.-Feb. Carolina University, Greenville, IMC). Journal of Applied Physiology: 1981, p. 45-53. 17 refs. In Russian. Respiratory, Environmental and Exercise Physiology, vol. 52, Jan. Cardiovascular and autonomic neuronal responses to acute emotional stress induced by the electrical stimulation of the 1982, P. 27-33. 30 refs. hypothalamus and skin are investigated in immobilized chinchilla rabbits. Measurements of arterial pressure and heart rate were A82-21928 * Phase V of the single-breath washout test. G. obtained as a function of time during the experiment, along with M. Nichol, 0. B. Michels, and H. J. B. Guy (Christchurch Clinical determinations of water-soluble protein content, neuronal cell body School of Medicine, Christchurch, New Zealand; California, Univer- and nuclear volume and weight in neurons of the superior cervical sity, La Jolla, CA). Journal of Applied Physiology: Respiratory, ganglion, nodose ganglion, stellate ganglion and sympathetic chain. Environmental and Exercise Physiology, vol. 52, Jan. 1982, p. 34-43. From the cardiovascular responses it was possible to identify three 34 refs. Research supported by the Medical Research Council of New types of reactions: resistance, adaptation, and the development of Zealand and North Canterbury Hospital; Grant No. NsG-9075. stress effects. Various metabolic changes were observed in the A downward-deflecting phase V is often seen following the extramural autonomic neurons of the stress-susceptible animals, the terminal rise (phase IV) in single-breath washout tests. To investigate most marked being an enhancement of catabolism in the nodose the nature of phase V, experiments using simultaneous washouts of ganglion. A tendency towards increased activity of the fast isoen- N2 and tracer boluses of Ar were performed on eight normal zymes of lactate dehydrogenase is also observed in the conductive nonsmoking subjects aged 27-41 who exhibited a phase V. Phase V is system of the heart. A.L.W. found to occur in all subjects at expiratory flow rates between 0.1 and 2.0 I/sec shortly after expiration became flow limited. Volumes A82-21826 t Comparative study of several physiological of both phases IV and V increase with increasing flow rate. The parameters in the evaluation of functional condition in nurses difference between the exhaled volumes at which flow became (Sravnitel'noe izuchenie nekotrykh fiziologicheskikh pokazatelei pri limited and phase V appeared is shown to be approximately equal to otsenke funktsional'.nogo sostoianiia u meditsinskikh sester). P. the anatomic dead space. Results support a model of lung emptying Ullsperger, H.-G. Gille, E. Otto, M. Pietschmann, B. Weickmann in a gravitational field in which flow limitation occurs first in the (Ministerstvo Zdravookhraneniia GDR, Tsentral'nyi Institut Rabo- lower lung regions and then progresses toward the upper regions, chei Meditsiny, Berlin, East Germany), and L. la. Zybkovets causing phase IV. A decrease in the amount of flow from the upper (Akademiia Meditsinskikh Nauk' SSSR, (Moscow, USSR). Gigiena relative to the lower regions after all regions have become flow Truda i Professional'nye Zabolevaniia, July 1981, p. 23-27. 11 refs. limited then causes phase V. A.L.W. In Russian. The effects of night work on psychophysiological reactions are A82-21929 A computational model for expiratory flow. investigated together with the usefulness of several neurophysiologi- R. K. Lambert, T. A. Wilson, R. E. Hyatt, and J. R. Rodarte cal methods in assessing functional condition following night work (Minnesota, University, Minneapolis; Mayo Clinic and Mayo Founda-

119 A82-21930

tion, Rochester, MM). Journal of Applied Physiology: Respiratory, A82-21933 Sum ma ted circulatory responses of thermal Environmental and Exercise Physiology, vol. 52, Jan. 1982, p. 44-56. and baroreflexes in humans. T. J. Ebert, D. F. Stowe, J. A. Barney, J. 18 refs. Grant No. NIH-HL-21584. H. Kalbfleisch, and J. J. Smith (U.S. Veterans Administration A mathematical model of maximal expiratory flow was de- Medical Center, Wood; Wisconsin Medical College, Milwaukee. Wl). veloped. Coupled equations describing the pressure losses in the flow Journal of Applied Physiology: Respiratory, Environmental and and the pressure-area behavior of the airway were integrated along Exercise Physiology, vol. 52, Jan. 1982, p. 184-189. 35 refs. the airway from the periphery to the flow-limiting site. Equations Interactions between thermal and baroreceptor inputs in the describing pressure losses in the flow were adapted from studies of elicitation of cardiovascular reflexes are investigated in a study of the bronchial casts. The bronchial anatomy utilized was that described integration of multiple afferent information by the vasomotor by Weibel. Bronchial mechanical properties were obtained from centers. Noninvasive techniques were used to monitor variations in measurements in excised human lungs for the central airways and by blood flow parameters induced by changes in central blood volume extrapolations of these data for the peripheral airways. The maximal created by lower body negative pressure and leg elevation in the flow for air and helium predicted by the model agrees with that of presence or absence of local thermal receptor stimulation by hand five lungs from which mechanical properties were obtained. The immersion in 10 C water. LBNP at -10, -25, and -40 Torr and leg model predictions agree with published values of density and elevation are found to result in changes in forearm vascular viscosity dependence of maximal flow. At high and midlung volumes, resistance, while the two high levels of LBNP are accompanied by maximal flow is determined primarily by the wave-speed mechanism. decreases in stroke volume, caridac index and blood pressure and At low lung volumes, maximal flow is primarily determined by the increases in heart rate and total peripheral resistance. Total periph- coupling of viscous pressure losses and airway mechanical properties. eral resistance, forearm vascular resistance and blood pressure are (Author) also observed to increase during hand immersion. Combined stimuli induced simple additive responses in all variables except heart rate, A82-21930 Rate of uptake of carbon monoxide at where a central interaction between thermal and baroreflex control different inspired concentrations in humans. H. A. Jones, J. C. Clark, of heart rate is indicated. A.L.W. E. E. Davies, R. E. Forster, and J. M. 8. Hughes (Royal Postgraduate Medical School, London, England; Pennsylvania, University, Philadel- A82-21934 Effects of temperature on the duration of phia, PA). Journal of Applied Physiology: Respiratory, Environ- arousal episodes during hibernation. A. R. French (California, mental and Exercise Physiology, vol. 52, Jan. 1982, p. 109-113. 15 University, Riverside, CM. Journal of Applied Physiology: Respira- refs. Grants No. NIH-HL-19737; No. NIH-5-P50-HL-15061-10. tory, Environmental and Exercise Physiology, vol. 52, Jan. 1982, p. 216-220. 23 refs. Research supported by the University of California; A82-21931 Air embolism - Possible role of surfactant on NSF Grant No. DEB-80-03513. recompression. B. A. Hills and R. E. Barrow (Texas, University, Houston, TX). Journal of Applied Physiology: Respiratory, Environ- A82-21935 Pulmonary gas exchange during altered density mental and Exercise Physiology, vol. 52, Jan. 1982, p. 119-123. 25 gas breathing. S. K. Christopherson and M. P. Hlastala (Washington, refs. University, Seattle, WA). Journal of Applied Physiology: Respira- The influence of lung surfactants on the passage of venous gas tory, Environmental and Exercise Physiology, vol. 52, Jan. 1982, p. emboli through the pulmonary circulation into arterial blood during 221-225. 21 refs. Grants No. NIH-HL-12174; No. NIH-HL-06081-02. recompression treatment is investigated. Relationships between The role of changes in the alveolar ventilation/perfusion apparent surface tension and surface area were determined with a distribution in determining the improvement in alveolar-arterial gas Wilhelmy balance for the first compression of films of the pulmonary exchange observed during breathing of carrier gases with increased surfactants dipalmitoyl lecithin (DPL), dipalmitoyl phosphatidyle- density is investigated. The alveolar ventilation/perfusion distribution thanolamine (DPPE) and sphyngomyelin under simulated physiolog- was measured directly by the multiple inert gas elimination tech- ical conditions. Results show that DPL reduces apparent surface nique and compared to changes in the alveolar-arterial 02 partial tension appreciably more than DPPE or sphygomyelin at the same pressure difference in dogs ventilated with room air alone or with a surface concentration, producing tensions below 8 dyn/cm, the 20.9% 02 in He mixture. While no difference between air and heliox highest level at which normal pulmonary systeolic pressure could is observed in the overall cardiorespiratory parameters, oxygen force trapped air into systemic arterial blood. Additional experi- exchange is observed to worsen with heliox breathing, as the alveolar ments in which compression was stopped for 1-min intervals as soon ventilation/perfusion distribution improved slightly. It is thus con- as surface tension fell below 15 dyn/cm demonstrate the possibility cluded that the improvement in oxygen exchange cannot be of reaching compression levels of up to 30% without accompanying explained by an improvement in ventilation/perfusion distribution; excessively low surface tension. Results support the rule of stopping an alternative mechanism involving the interaction of diffusion and compression in cases of limb bends at 60 fsw, and suggests the convection on inspiration is suggested. A.L.W. advisability of stopping at the depth of relief. A.L.W. A82-21936 Cardiac output increase and gas exchange at A82-21932 Erythrocyte indices during a competitive start of exercise. M. L. Weissman, P. W. Jones, A. Oren, N. Lamarra, marathon. M. A. Kolka, L. A. Stephenson, and J. E. Wilkerson B. J. Whipp, and K. Wasserman (California, University, Torrance, (Indiana University, Bloomington, IN). Journal of Applied Physiol- CA). Journal of Applied Physiology: Respiratory, Environmental and ogy: Respiratory, Environmental and Exercise Physiology, vol. 52, Exercise Physiology, vol. 52, Jan. 1982, p. 236-244. 17 refs. Grants Jan. 1982, p. 168-172. 32 refs. No. NIH-HL-07388; No. NIH-HL-11907. Changes in erythrocyte count, plasma osmolality and erythro- The dynamics of the increase in alveolar gas exchange induced cyte indicators occurring within the course of long-duration exercise by increasing cardiac output pursuant to the onset of exercise is are investigated. Measurements of the hematocrit, whole blood investigated. Temporal patterns of gas exchange were measured hemoglobin concentration and erythrocyte counts were made in during the first 10-20 sec of cycle ergometer exercise with minute blood drawn from three healthy adult males immediately prior to ventilation constant at the resting level and during a single prolonged and at 4.8-km intervals during a competitive marathon (42.2 km). constant airflow exhalation. A rapid response of increased gas Despite running times of 3, 4 and 5 hr, the erythrocyte count is exchange following the beginning of exercise is evidenced by a found to decrease linearly for the first 15 km of the race in all progressive elevation in alveolar C02 tension and fall in 02 tension in subjects, reaching a level 4.7% below the prerace control, then to rise the controlled ventilation experiment, and by a steepening of the back to control levels by 19.3 km, where it remained for the slope of the alveolar phase of 02 and C02 in the prolonged remainder of the race. Calculated values of the mean corpuscular exhalation experiment. These changes, which would occur during the hemoglobin concentration, mean corpuscular hemoglobin, and total first one to two breaths of exercise in free-breathing subjects, are red blood cell volume did not change significantly during the race, attributable to a reduction in overall pulmonary ventilation/ while plasma osmolality increased linearly and mean corpuscular perfusion ratio as cardiac output rapidly increased. A.L.W. volume displayed a negative linear correlation with osmolality. Data demonstrate the value of obtaining sequential blood samples during an exercise bout, as well as the ability of the organism to maintain A82-21987 Possible impact of cosmochemistry on ter- erythrocyte indices within narrow limits. A.L.W. restrial biology - Historical introduction. N. W. Pirie (Rothamsted

120 A82-22249

Experimental Station, Harpenden, Herts., England). (Royal Society, cue fidelity and for imposing realistic workload and attentional Discussion on Molecules in Interstellar Space, London, England, May demands on the simulator pilot. (Author) 20, 21, 1981.) Royal Society (London), Philosophical Transactions, Series A, vol. 303, no. 1480, Dec. 24, 1981, P. 589-594. 29 refs. A82-22200 Genetic damage in Escherichia coli K12 Attention is given to opinions held by prominent men regarding AB2480 by broad-spectrum near-ultraviolet radiation. R. B. Webb the existence of life on celestial bodies other than earth, taking into and M. S. Brown (Argonne National Laboratory, Argonne, IL). account philosophers in ancient Greece, and scientists and non- Science, vol. 215, Feb. 19, 1982, p. 991-993. 26 refs. Contract No. scientist intellectuals in Europe. It is found that pluralism was the W-31-109-eng-38. dominant outlook during the last few centuries. The separation of a belief in life elsewhere from a belief in intelligence elsewhere had to await the resolution of the spontaneous generation controversy. A82-22206 *' The thermal response of a human in the Extraterrestrial intrusion had been postulated to explain specific near-zone of a resonant thin-wire antenna. R. J. Spiegel (U.S. biological phenomena. The general proposition that all life came here Environmental Protection Agency, Health Effects Research Lab- from elsewhere seems to have originated with Richter (1865). The oratory, Research Triangle Park, NC). IEEE Transactions on Micro- concepts of an introduction of 'seeds' from space to earth is wave Theory and Techniques, vol. MTT-30, Feb. 1982, p. 177-185. considered along with the impact which components of meteorites 14 refs. and cosmic dust may have on biology. G.R. The thermal response of a human in the near-zone of a resonant thin-wire antenna has been determined using a model consisting of a series of transient conduction equations with internal heat generation A82-21988 Organic matter in meteorites and Precambrian due to metabolism, internal convective heat transfer due to blood rocks - Clues about the origin and development of living systems. J. flow, external reaction by convection and radiation, and cooling of Brooks (British National Oil Corp., Exploration Div., Glasgow, the skin by sweating and evaporation. Numerical results are Scotland). (Royal Society, Discussion on Molecules in Interstellar presented for two cases: a human in the near-zone of a quarter-wave Space, London, England, May 20, 21, 1981.1 Royal Society monopole and a half-wave dipole operating at 45 and 200 MHz, (London), Philosophical Transactions, Series A, vol. 303, no. 1480, respectively. It is found that thermal effect is negligible for antennas Dec. 24, 1981, p. 595-608; Discussion, p. 608, 609. 77 refs. with input power levels of less than 50 W. V.L. Modern hypotheses about the origin of life on earth follow suggestions made originally by Oparin (1924) and Haldane (1929) A82-22248 * Enzymatic capacities of skeletal muscle - about a chemical synthesis in which precursors of biomolecules could Effects of different types of training. F. W. Booth (Texas, University, be formed from a primitive early atmosphere. The current knowledge Houston, TX) and G. R. Hugman (Baylor College of Medicine, of the abiogenesis of organic molecules is derived from the Houston, TX). Medicine and Sport, vol. 13, 1981, p. 153-164. 39 identification of organic molecules in astronomical spectra, the refs. Research supported by the Muscular Dystrophy Association of presence of organic compounds in carbonaceous chondrites, studies America; Grant No. PHS-AM-19393; Contract No. NAS9-15388. of the organic contents in early Precambrian rocks, and laboratory Long-term adaptation mechanisms to maintain homeostasis at experiments. The considered investigation is concerned with an increased levels of exertion such as those caused by regular exercise evaluation of the available information against the Oparin-Haldane are described. Mitochondrial changes have been found to be a result hypothesis, taking into account the ancient geological record and of endurance exercises, while mitochondrial responses to other types information contained in carbonaceous chondrites. G.R. of exercise are small. Further discussion is devoted to long-term changes in glucose transport, hexokinase, phosphofructokinase, A82-21989 Problems in the rate of evolution in biological pyruvate kinase, and the increased sensitivity of an endurance trained systems. F. R. Whatley (Oxford University, Oxford, England). muscle to insulin. Less lactate has been found to be produced by the (Royal Society, Discussion on Molecules in Interstellar Space, skeletal muscles at the same work rate after adaptation to endurance London, England, May 20, 21, 1981.) Royal Society {London), exercise training, and the capacity for the flux of the two-carbon Philosophical Transactions, Series A, vol. 303, no. 1480, Dec. 24, acetyl chain through the citric acid cycle increases in skeletal muscles 1981, p. 611-622; Discussion, p. 622, 623. 18 refs. in response to endurance training. Finally, endurance training is Questions regarding the earliest organization of systems leading noted to result in glycogen sparing and an increase in the capacity to to the evolution of life are considered, taking into account the amino utilize fatty acids. M.S.K. acids of the prebiotic soup, and the adenine molecule as a component of the energy carrier ATP. Aspects of the biochemical A82-22249 * In vitro Ca-45/++/ uptake and exchange by evolution are examined, giving attention to living systems based on otoconial complexes in high and low K/+/Na/+/ fluids. M. D. Ross, proteins or nucleic acids, living systems based on nucleic acids, and K. G. Pole, P. L. Cloke, and C. Corson (Michigan, University, Ann living systems based on nucleic acids and proteins. The origin of Arbor, Ml). Physiologist, vol. 23, Dec. 1980, p. S-129, S-130. 10 refs. enzymatic systems is discussed. It is pointed out that a modern Grant No. NsG-9047. example of the self-assembly of a catalytic protein from its Recently, data have been accumulating to indicate that saccular constituent parts can be seen in the enzyme ferredoxin. The greatest and utricular otoconial complexes of the gravity receptor organs are single discontinuity in the evolution of living systems is thought to dynamic and interact constantly with their environment. This study be the attainment of the eukaryotic state of organization. According investigates the possibility that the ionic composition of the to the theory of serial endosymbiosis, the characteristic eukaryotic surrounding fluid influences calcium ion binding and release, and organelles are derived from unicellular symbionts. Attention is also explores the importance of the K(+)/Na(+) ratio. Two in-vitro given to the origin of chloroplasts. G.R. methods were developed, the first of which employed artificial endolymph and perilymph while ionically balanced fluids in which only the K(+)/Na(+) was altered were used in the second. The ability A82-22078 *,'••' A program for assessing pilot mental state in of rat complexes to take up Ca-45(++) during incubation with these flight simulators. A. T. Pope and R. L. Bowles (NASA, Langley fluids was assessed using liquid scintillation spectrometry. In vitro Research Center, Hampton, MM. American Institute of Aeronautics uptake of Ca-45(++) was greater in fluids with a high K(+)/Na(+) and Astronautics, Aerospace Sciences Meeting, 20th, Orlando, FL, ratio than in fluids in which the ratio was low. The ability of the Jan. 11-14, 1982. Paper 82-0257. 16 p. 17 refs. complexes to take up Ca-45(++) appeared to decline with age. A program to apply proposed measures of pilot mental state in (Author) the simulator flight deck environment has been undertaken at NASA Langley Research Center. Literature survey identified a promising subset of methods for assessing workload, attention and vigilance, and task-related stress, and revealed a need for improved analytical techniques in the physiological area. An effort to apply functional modelling techniques has been initiated. A psychophysiological laboratory has been designed for simulator application. The program is designed to develop improved techniques for evaluating simulator

121 N82-16706

N82-16703$ Cincinnati Univ., Ohio. Inst. of Environmental Health. MECHANISMS OF CADMIUM ABSORPTION IN RATS Ernest. C. Foulkes, D. R. Johnson, Naoki Sugawara, Roland F. Bonewitz. and Cathleen Voner Sep. 1981 59 p refs (Grant EPA-R-805840) STAR ENTRIES (PB82-108184; EPA-600/1-81-063) Avail: NTIS HC A04/MF A01 CSCL 06T The study was undertaken in order to help clarify the factors which determine the fractional absorption of an oral load of cadmium (Cd) from the intestine of the rat. The experiments N82-16700$ Oak Ridge National Lab., Tenn. Biology Div. utilized intact segments of intestine, perfused or incubated in POSSIBLE MECHANISM FOR CHEMICAL INDUCTION OF situ, with their blood supply intact. Absorption of Cd from the CHROMOSOME ABERRATIONS IN MALE MEIOTIC AND jejunal lumen can be ascribed to a saturable membrane system, POSTMEIOTIC GERM CELLS OF MICE that is after short periods of exposure essentially all the metal Walderico M. Generoso 1981 16 p refs Presented at 4th removed from the lumen was recovered in mucosal issue (Step Intern. Symp. of the Radiation Biol. Center. Kyoto, 28 Sep. 1981 1). The second step in Cd absorption, i.e.. transfer of the metal Sponsored in part by EPA from mucosa into blood, proceeded at only 1-2% of the rate of (DE81-031999: CONF-810966-1) Avail: NTIS uptake from the lumen (Step 1). No evidence was obtained for HC A02/MF A01 a role of metal lothionein in the mucosal retention of Cd. Step The mechanisms by which chemically induced lesions in 1 of Cd absorption was inhibited by a variety of exogenous and the chromosomes of mammalian germ cells are actually converted endogenous factors. Thus, zinc was found to depress Cd transport to aberrations and transmitted to progeny are investigated. An in an apparently competitive manner. Addition of milk to the attempt is made to explain how dominant-lethal mutations and lumen also inhibited Cd uptake, an effect entirely due to the Ca heritable translocations are produced from chemical treatment content. Bile salts act as endogenous modulators of Cd of meiotic and postmeiostic germ cells of male mice. DOE absorption: their effect may be related to micelle formation. The research also included studies of duodenal and ileal Cd transport. GRA

N82-16701$ Environmental Protection Agency, Corvallis. Oreg. Environmental Research Lab. VARIATION IN PLANT RESPONSE TO OZONE: A N82-16704$ Joint Publications Research Service, Arlington. CONCEPTUAL MODEL OF PHYSIOLOGICAL EVENTS D. T Tingey and G. E. Taylor, Jr. 1980 47 p refs Presented Va. at 32nd Symp on Effects of Gaseous Air Pollution in Agr. and USSR REPORT: SPACE BIOLOGY AND AEROSPACE Hort, Nottingham. England. 1 Sep. 1980 Prepared in cooperation MEDICINE. VOLUME 15, NO. 6. NOVEMBER - DECEMBER with Oak Ridge National Lab. 1981 12 Jan. 1982 154 p refs Transl. into ENGLISH of Kosm. (Contract W-7405-eng-26) (DE81-029692: CONF-8009172-1) Avail: NTIS Biol. Aviakosm. Med (Moscow), v. 15, no. 6, Nov - Dec. 1981 HC A03/MF A01 (JPRS-79849) Avail: NTIS HC A08/MF A01 The environment and genotype exert profound influences on Articles are presented which address life support systems; a plant's ozone response. Based on the multiplicity of physiological human and animal physiological responses to spacecraft environments, radiation and weightlessness; and flight fatigue in mechanisms responsible for variable response, a common progression of events is proposed: ozone conductance (gas and helicopter crews. liquid phase), perturbation, homeostasis, and injury. Injury is the repercussion of the preceeding events. Gas and liquid phase conductances are significant sources of variable ozone response. Genie expression and environmental stimuli affect ozone N82-16705$ Joint Publications Research Service, Arlington, conductance and homeostasis and thereby the extent of injury. Va. Based on conceptual model, gas phase conductance would be QUESTION OF REDISTRIBUTION OF BLOOD IN ORTHO- the decisive factor controlling injury only if it were the rate STATIC POSITION limiting step. Any physiologically significant intervening event G. S. Belkaniya In its USSR Rept: Space Biol. and Aerospace between gas-phase conductance and injury would reduce the Med., Vol. 15, No. 6, Nov. - Dec. 1981 (JPRS-79849) 12 Jan. association between them. Either liquid phase conductance of 1982 p 1-9 refs Transl. into ENGLISH from Kosm. Biol. homeostasis could reduce that association. DOE Aviakosm. Med. (Moscow), v. 15, no. 6. Nov. - Dec 1981 p 4-9

Avail: NTIS HC A08/MF A01 N82-16702$ Colorado State Univ.. Fort Collins. Dept. of The concept of two interacting constituents involved in the Microbiology. redistribution of the circulating blood volume in orthostasis. MICROBIOLOGICALLY MEDIATED MUTAGENIC ACTIVITY redistribution along the vertical (hydrostatic) and functional OF CRUDE OIL Final Report. 1976 - 1979 (metabolic) gradients, is discussed. On this basis, the possible Bruce A. Cummings and Ronald C. Gordon Sep. 1981 302 p mechanism responsible for orthostatic circulatory intolerance refs following an exposure to bed rest or weightlessness is de- (Grant EPA-R-805041) scribed. Author (PB82-105131: EPA-600/3-81-053) Avail: NTIS HC A14/MF A01 CSCL 06T Crude oil was incubated with raw and sterile river water samples and assayed for mutagenic activity for the Ames test N82-16706$ Joint Publications Research Service, Arlington, to determine the ability of naturally occurring freshwater Va. microorganisms to form mutagenic biodegradation products from WAYS AND MEANS OF MAINTAINING HEAT BALANCE crude oil. River water samples supplements with inorganic salts IN PILOTS AND COSMONAUTS were incubated with one percent crude oil in Erlenmeyer flasks A. S. Barer In its USSR Rept.: Space Biol. and Aerospace for 1-6 weeks and 4 and 20 C with shaking. Replicate flasks Med., Vol. 15, No. 6. Nov. - Dec. 1981 (JPRS-79849) 12 Jan. were extracted at various time intervals with 1,1-2 trichloro-1,2,2- 1982 p 10-18 refs Transl. into ENGLISH from Kosm. Biol. trifluoroethane, the solvent evaporated and the residues taken Aviakosm. Med. (Moscow), v 15, no. 6, Nov.- Dec. 1981 p 9-15 up in dimethyl sulfoxide for mutagenicity testing. The extracts were assayed for mutagenic activity by the plate incorporation Avail: NTIS HC A08/MF A01 method of the Ames test with Salmonella tester strains TA 100. Different principles used in systems ensuring thermal balance TA 1535. TA 1537, TA 1538 and TA 98. Mammalian liver of pilots and cosmonauts are discussed. Physiological and hygienic microsomes were not used in the mutagenicity test system as characteristics of the passive thermal insulation, ventilation the oil degrading microorganisms constituted the enzyme systems, and liquid cooling (heating) suits are presented. A activation system in the study. GRA classification of the means and methods is proposed. Author

123 N82-16707

N82-16707# Joint Publications Research Service, Arlington. To'Obtain reference data for a statistically substantiated Va. evaluation of man's tolerance to the local pressure on the head SYSTEMIC AND CEREBRAL HEMODYNAMICS IN FLIGHT (as applied to protective helmets kept on for a long time). PERSONNEL EXPOSED TO MODERATE HYPOXIA 86 experiments were carried out in which 11 test subjects V. N. Denisov. S. F. Rayev, and I. I. Antufyev In its USSR participated. The local pressure of 0.05 to 0.5 kg/sq cm was Rept.: Space Biol. and Aerospace Med.. Vol. 15. No. 6. Nov. - applied to eight areas of the head. The tolerance time was Dec. 1981 (JPRS-79849) 12 Jan. 1982 p 19-23 Transl. measured as the time interval from the beginning of the exposure into ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15. to the emergence of localized sensations of the type: unpleasant, no. 6. Nov. - Dec. 1981 p 16-19 painful, very painful, or intolerable. As a result, statistically significant relationships between the tolerance.time and the level Avail: NTIS HC A08/MF A01 of the local pressure were obtained for the eight locations and For the purposes of medical expertise the state of systemic four grades of subjective sensations. These data can be used in and cerebral hemodynamics was investigated in 66 pilots with evaluating protective helmets to be worn for a long time as autonomic-vascular instability and in 36 healthy subjects exposed well as in developing hygienic requirements for the advanced to moderate hypoxia (in an altitude chamber). The pilots showed helmet-like devices. Author noticeable tachycardia or systolic hypertension, as well as certain changes in cardiac output and stroke volume. These alterations N82-16711$ Joint Publications Research Service, Arlington. were accompanied by rheoencephalographic changes of two types Va. one of which can be regarded as an adverse response of cerebral EFFECT OF TRANSMERIDIONAL FLIGHTS ON BIORHYTHM circulation to hypoxia. It is concluded that the study of systemic OF ZONE FORMATION BY STREPTOMYCES LEVORIS and cerebral circulation in hypoxia yields important diagnostic information that allows better estimates. M.G. A. P. Savelyev. A. Kh. Akhmadiyeva, and I. G. Akoyev In its USSR Rept.: Space Biol. and Aerospace Med.. Vol 15, No. 6, N82-16708$ Joint Publications Research Service, Arlington. Nov. - Dec. 1981 (JPRS-79849) 12 Jan. 1982 p 38-41 Va. refs Transl. into ENGLISH from Kosm. Biol. Aviakosm. Med. CAUSES OF FATIGUE AMONG CREWS OF CIVIL AVIATION (Moscow), v. 15. no. 6. Nov. - Dec. 1981 p 28-31 HELICOPTERS Yu. N. Kamenskjy In its USSR Rept.. Space Biol. and Aerospace Avail: NTIS HC A08/MF A01 Med., Vol. 15, No. 6. Nov. - Dec. 1981 (JPRS-79849) 12 Jan. The transmeridioneal transportation of the temperature 1982 p 24-27 refs Transl. into ENGLISH from Kosm. Biol. controlled colonies of Streptomyces levoris exerted a marked Aviakosm. Med. (Moscow), v. 15. no. 6. Nov. - Dec. 1981 effect on its biorhythms. This included changes in the growth p 19-22 and zone formation rates and differences in the vector of changes Avail: NTIS HC A08/MF A01 as related to the flight direction. The vector of changes during The role of vibration and noise in the development of fatigue an east-oriented airborne flight coincided with that in orbital in helicopter crews was assessed. The exposure to these factors flight with a similar direction of transportation. These findings during the flying shift results in an early and marked fatigue of as well as the results of studies of seasonal and diurnal rhythms pilots the level of which depends on the vibration effects to a of the actinomycete zone formation suggest the synchronizing larger extent than on the noise effects. The fatigue is followed effect of the periodicity of geophysical factors. M.G by a decline of the psychophysiological parameters characterizing N82-16712$ Joint Publications Research Service, Arlington, the visual and motor functions as well as the ratio of the basic Va. processes in the central nervous system M.G. SIMULATION OF SOME OF MAN'S MOVEMENTS IN DIFFERENT GRAVITY FIELDS N82-16709$ Joint Publications Research Service. Arlington. A. V. Zinkovskiy, I. A. Trofimova. and V. A. Chistyakov In its Va. USSR Rept.: Space Biol. and Aerospace Med., Vol. 15. No. 6. PHYSIOLOGICAL AND HYGIENIC EVALUATION OF Nov. - Dec. 1981 (JPRS-79849) 12 Jan. 1982 p 42-45 VIBRATION IN THE COCKPIT OF A CARGO HELICOPTER refs Transl. into ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15, no. 6, Nov. - Dec. 1981 p 31-33 Yu. G. Matveyev and Yu. N. Kamenskiy In its USSR Rept.: Space Biol. and Aerospace Med.. Vol. 15. No. 6. Nov. - Dec. Avail: NTIS HC A08/MF A01 1981 (JPRS-79849) 12 Jan. 1982 p 28-32 refs Transl. The control of man's movements during adaptation to an into ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15. altered gravity field was modeled by mathematical methods. Two no. 6. Nov. - Dec. 1981 p 22-25 types of movements were investigated: forearm displacement with various loads and repulsions from a support in zero-G and Avail: NTIS HC A08/MF A01 at high G's. It was shown that movement coordination in altered The correlations between statistical parameters of vibration gravity fields can be maintained due to a rearrangement of the in the work place, work schedules, and functional state of subjects control over muscle contraction which includes changes in the when performing commercial flights were studied. In the cockpit amplitude and pattern of joint momenta in harmony with the of five helicopters the floor and the chair vibrated in a band of gravity changes. M.G. 8 Hz at a frequency of 112.5 and 114.0 dB, respectively. Before and after the flying shift 66 crewmembers were interviewed N82-16713$ Joint Publications Research Service. Arlington. and examined. Vibration was referred to as the most unpleasant Va factor by 30.4% of them, noise was defined as the most unpleasant POSITIONS. MOVEMENTS AND EQUILIBRIUM OF RATS factor by 6.5% of them; 63.1% described both factors as similarly AFTER FLIGHTS ABOARD BIOSATELLITES adverse. The level of psychophysiological changes was proportional G. S. Ayzikov and A. S. Markin In its USSR Rept.: Space to the flight time. The first signs of fatigue were seen after Biol. and Aerospace Med.. Vol. 15. No. 6, Nov. - Dec. 1981 flights of up to 5 hours in duration, to increase drastically after (JPRS-79849) 12 Jan. 1982 p 46-53 refs Transl. into flights of 6 and 7 hours. • M.G. ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15. no. 6. Nov. - Dec. 1981 p 33-38 N82-16710$ Joint Publications Research Service. Arlington, Va. Avail: NTIS HC A08/MF A01 EVALUATION OF MAN'S ENDURANCE OF LOCAL PRES- An examination of the Wistar-SPF rats flown onboard the SURE TO THE HEAD AND OBJECTIVE ASSESSMENT OF biosatellites Cosmos 782. 936 and 1129 demonstrated significant HYGIENIC SPECIFICATIONS FOR PROTECTIVE HELMETS changes in their postural, motor, and equilibrium reactions. The use of artificial gravity inflight produced a beneficial effect on V. M. Sinigin, Yu. G. Konakhevich, L. N. Sholpo. and A. I. Uglanov the health state, motor activity, and simple reflex acts of the In its USSR Rept.: Space Biol. and Aerospace Med., Vol. 15. animals but worsened their movement coordination and equilib- No. 6. Nov. - Dec. 1981 (JPRS-79849) 12 Jan. 1982 p 33-37 rium function. M.G. Transl. into ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15. no. 6. Nov. - Dec. 1981 p 25-28 N82-16714$ Joint Publications Research Service, Arlington. Va. Avail: NTIS HC A08/MF A01 CATHEPSIN ACTIVITY OF SKELETAL MUSCLE AND

124 N82-16721

MYOCARDIA MYOFIBRILS AFTER EXPOSURE TO WEIGHT- The hygienic principles used in the evaluation of the quality LESSNESS AND ACCELERATIONS of reclaimed water onboard the spacecraft are presented. The S. S. Oganesyan and M. A. Eloyan In its USSR Rept.: Space parameter required for operational control and their hygienic Biol. and Aerospace Med.. Vol. 15. No. 6. Nov. - Dec. 1981 significance are discussed. Author (JPRS-79849) 12 Jan. 1982 p 54-59 refs Transl. into ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15. N82-16718# Joint Publications Research Service. Arlington. no. 6. Nov. - Dec. 1981 p 38-42 Va. TOXICOLOGICAL AND HYGIENIC ASPECTS OF IMPROV- Avail: NTIS HC A08/MF A01 ING ADDITIONAL PURIFICATION OF WATER RECLAIMED The rats flown onboard Cosmos-605 and exposed to a FROM URINE synchronous experiment for 22 days showed an increased activity Z. P. Pak. G. V. Lobacheva, M. M. Spiryayeva. Yu. Ye. Bezumova. of myofibrillar cathepsins in skeletal muscles of different groups. T. P. Korotkova. V. P. Petina. and Ye. S. Yevdokimova In its In the flight rats the increase was greater than in the synchronous USSR Rept.. Space Biol. and Aerospace Med.. Vol. 15. No. 6. ground-based animals. This suggests a significant effect of Nov. - Dec. 1981 (JPRS-79849) 12 Jan. 1982 p 73-78 weightlessness on the cathepsic activity. The parameter was refs Transl. into ENGLISH from Kosm. Biol. Aviakosm. Med. partially normalized at R + 25 or 26 days. The exposure of rats (Moscow), v. 15. no. 6. Nov. - Dec. 1981 p 51-54 to accelerations of 4 and 5 G for 2 min daily during 2 weeks also increased the cathepsic activity of skeletal and myocardial Avail: NTIS HC A08/MF A01 myofibers. The parameter returned to normal a month after Comparative toxicological and hygienic studies of samples completion of acceleration exposures. Thus, changes in the of reclaimed water obtained from urine with the use of different proteolytic activity of myofibers of different muscles induced by final purification variants were conducted. The sorption-catalytic weightlessness and acceleration are reversible. The significance method of urine condensate repurification using a platinum-carbon of changes in the muscle tension as related to the mechanism catalyst proved to be the most promising since it can ensure of stimulation of proteolytic reactions is discussed. M.G. the production of lexicologically safe potable water. It was shown experimentally that the quality of reclaimed water as related to N82-16715# Joint Publications Research Service, Arlington. its chemical and toxicological parameters depends on the efficiency Va. of the repurification unit. B.W. CYTOKINETIC EVALUATION OF ERYTHROPOIESIS DUR- ING LONG-TERM ORBITAL FLIGHTS N82-16719# Joint Publications Research Service. Arlington, A. V. llyukhin and T. Ye. Vurkovskaya In its USSR Rept.: Space Va. Biol. and Aerospace Med., Vol. 15, No. 6, Nov. - Dec. 1981 POSSIBLE USE OF HOUSE FLY LARVAE FOR UTILIZATION (JPRS-79849) 12 Jan. 1982 p 60-64 refs Transl. into OF ORGANIC WASTE IN BIOLOGICAL LIFE-SUPPORT ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15. SYSTEMS no. 6. Nov. - Dec. 1981 p 42-46 Ye. G. Golubeva and T. V Yerofeyeva In its USSR Rept.: Space Biol. and Aerospace Med, Vol. 15, No. 6, v. - Dec. 1981 Avail: NTIS HC A08/MF A01 (JPRS-79849) 12 Jan. 1982 p 79-83 refs Transl. into The mechanisms of erythropoietic changes at the cellular ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15, level during a prolonged exposure to weightlessness were no. 6, Nov. - Dec. 1981 p 54-57 investigated. Following 96-, 140- and 175-day space flights cytokinetic and morphological changes in erythropoiesis were Avail: NTIS HC A08/MF A01 observed. The count of circulating erythrocytes decreased inflight Musca domestica larvae were grown in organic substrates and their life time reduced postflight. The shortening of the life of three types. The larval density was shown to influence certain time of erythrocytes postflight was paralleled by increased parameters characterizing the fly life cycle and the larval utilization proliferative activity of erythroid cells. The erythrocytic balance of the substrate. The larval development led to a decrease of was not reached as late as R + 36 days. B.W. the substrate mass, humidity and the content of organic matter. Man's native excrements were found to be the best substrate N82-16716# Joint Publications Research Service. Arlington. for M. domestica larvae. Author Va. NOREPINEPHRINE AND ENZYMES OF SYNTHESIS AND DEGRADATION THEREOF IN THE RAT HYPOTHALAMUS N82-16720# Joint Publications 'Research Service, Arlington, FOLLOWING FLIGHT ABOARD THE COSMOS 936 BIOSAT Va. ELLITE DISTINCTIONS OF REGENERATION OF CONFINED T. Torda. R. Kvetnyanski. R. A. Tigranyan. Yu. Chulman, and A. ATMOSPHERE BY MEANS OF PHOTOSYNTHESIS OF M. Genin In its USSR Rept.: Space Biol. and Aerospace Med.. UNICELLULAR ALGAE Vol. 15. No. 6, Nov. - Dec. 1981 (JPRS-79849) 12 Jan. G. I. Meleshko, L. M Krasotchenko, and Ye. K. Lebedeva In its 1982 p 65-68 refs Transl. into ENGLISH from Kosm. Biol. USSR Rept.: Space Biol. and Aerospace Med.. Vol. 15, No. 6. Aviakosm. Med. (Moscow), v. 15. no. 6, Nov. - Dec. 1981 Nov. - Dec. 1981 (JPRS-79849) 12 Jan. 1982 84-90 refs p 46-48 Transl. into ENGLISH from Kosm. Biol. Aviakosm. Med (Moscow). Avail: NTIS HC A08/MF A01 v. 15. no. 6, Nov. - Dec. 1981 p 58-62 In the hypothalamus of weightless and centrifuged rats flown for 18.5 days onboard the biosatellite Cosmos-936, the noradren- Avail: NTIS HC A08/MF A01 aline concentration and activity of the enzymes involved in the Systems of biological air regeneration using photosynthesis catecholamine synthesis and degradation were measured. It was of unicellular algae are examined. An oxygen-carbon dioxide found that under the space flight 'influence the noradrenaline mismatch associated with the difference in gas exchange concentration and tyrosine hydroxylase. dopamine-beta- coefficients of man and algae is shown. The value and vector hydroxylase. and monoamine oxidase activities remained unaltered. of the mismatch depend on the degree of the above difference. These findings indicate that a prolonged exposure to weightless- In the system balanced with respect to oxygen consumption ness was not a stressogenic agent that could activate the and carbon dioxide production, the rate of the mismatch equals adrenergic system in the rat hypothalamus. B.W. to 1 per cent of either process per each unit of the difference of the gas exchange coefficients in the second decimal point. Methods for regulating the algal assimilation coefficient based N82-16717# Joint Publications Research Service. Arlington, on the use of various nitrogen forms for algal nutrition and Va. controlled biosynthesis are discussed. Optimal variants of gas HYGIENIC PRINCIPLES OF ONGOING MONITORING OF exchange balance in the semi-closed biological life support systems QUALITY OF RECYCLED WATER DURING SPACE are described. B.W. FLIGHTS V. M. Skuratov. V. B. Gaydadymov, and S. V. Chizhov In its USSR Rept.: Space Biol. and Aerospace Med., Vol. 15. No. 6. . N82-16721# Joint Publications Research Service, Arlington. Nov. - Dec. 1981 (JPRS-79849) 12 Jan. 1982 p 69-72 Va. refs Transl. into ENGLISH from Kosm Biol. Aviakosm Med. PHENOMENA OF FLUCTUATION OF HUMAN REACTION (Moscow), v. 15. no. 6. Nov. - Dec. 181 p 48-51 TO ANTIORTHOSTATIC POSITION L. Lkhagva In its USSR Rept.: Space Biol. and Aerospace Avail: NTIS HC A08/MF A01 Med., Vol. 15. No. 6. Nov. - Dec. 1981 (JPRS-79849) 12 Jan.

125 N82-16722

1982 p 91-94 refs Transl. into ENGLISH from Kosm. Biol. from the heart, thus, together with other factors, leading to Aviakosm. Med. (Moscow), v. 15, no. 6. Nov. - Dec. 1981 disorders in the heart energetics. These findings indicate an p 63-65 important role of hypoxic hypoxia in the disturbances of lipid Avail: NTIS HC A08/MF A01 metabolism of the myocardium. This needs to be taken into The biorhythmological analysis of the data obtained from consideration in the diagnostics and treatment of such states. seven healthy male test subjects in the head-down position at Author -8 deg revealed phemonena of sine-shaped reactions. This pattern was seen in the range (the difference between mean day-time N82-16725$ Joint Publications Research Service. Arlington, and mean night-time values) of heart rate, amplitude (the difference Va. between the maximum and minimum) of variations of body STATIONARY MAGNETIC FIELDS AND RETICULAR temperature and renal potassium excretion, and the evening- INFLUENCES ON ADRENERGIC AND CHOLINERGIC morning difference of body temperature variations. Author SYSTEMS L. D. Klimovskaya and A. F. Maslova In its USSR Rept.: Space N82-16722$ Joint Publications Research Service, Arlington, Biol. and Aerospace Med. Vol. 15, No. 6, Nov. - Dec. 1981 Va. (JPRS-79849) 12 Jan. 1982 p 109-112 refs Transl. into RESULTS OF STUDY OF HEMOOYNAMICS AND PHASE ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15, STRUCTURE OF THE CARDIAC CYCLE DURING FUNC- no. 6, Nov. - Dec. 1981 p 74-76 TIONAL TEST WITH LOWER BODY NEGATIVE PRESSURE DURING 140-DAY SALYUT-6 STATION FLIGHT Avail: NTIS HC A08/MF A01 A. D. Yegorov. 0. G. Itsekhovskiy, I. I. Kasyan, A. P. Polyakova, An exposure of rabbits to a constant magnetic field of 0.4 T V. F. Turchaninova. I. V. Alferova. V. G. Savelyeva. M. V. for one hour caused increases in the blood content of adrenaline, Domracheva. V. G. Doroshev. Ye. A. Kobzev et al In its USSR noradrenaline, and acetylcholine. and in the adrenal content of Rept.: Space Biol. and Aerospace Med. Vol. 15. No. 6. Nov. - adrenaline. Stimulation of the midbrain reticular formation led Dec. 1981 (JPRS-79849) 12 Jan. 1982 p 95-100 refs to a significant increase of the blood concentration of catechola- Transl. into ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), mines and acetylcholine. After an exposure to the constant v. 15. no. 6, Nov. - Dec. 1981 p 65-69 magnetic field the stimulatory effects of the reticular formation on the adrenergic systems diminished and on the cholinergic Avail: NTIS HC A08/MF A01 systems remained elevated. R.J.F. The two members of the 140-day permanent Salyut-6 space N82-16726$ Joint Publications Research Service, Arlington, flight were exposed to five lower body negative pressure (LBNP) tests at -25 and -35 mm Kg for 2 and 3 min. respectively. Va. Circulation responses to the LBNP tests were measured with CLINICAL DISTINCTIONS OF RADIATION SICKNESS WITH respect to the heart rate, arterial pressure, chronocardiogram. EXPOSURE OF DIFFERENT PARTS OF THE HUMAN BODY TO RADIATION and cardiac output. As compared to the preflight data, inflight G. F. Nevskaya, G. M. Abramova. M. A. Volkova. Ye. V. Kavlycheva. responses were characterized by a greater tachycardia, preload A S. Skorik. and V. V. Yurogov In its USSR Rept.: Space insufficiency, and vascular tone in the absence of orthostatic intolerance. Possible mechanisms of the changes in the circulation Biol. and Aerospace Med.. Vol. 15. No. 6. Nov. - Dec. 1981 responses are discussed. Author (JPRS-79849) 12 Jan. 1982 p 113-118 refs Transl. into ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15. no. 6. Nov. - Dec. 1981 p 77-80 N82-16723| Joint Publications Research Service. Arlington, Va. Avail: NTIS HC A08/MF A01 SUCCINATE DEHYDROGENASE AND CYTOCHROME The clinical picture of radiation sickness of 139 radiological OXIDASE ACTIVITY IN TISSUES OF RATS SUBMITTED patients exposed to local irradition of the head, chest, and TO LONG-TERM HYPOKINESIA stomach with efficient doses of 210 rad was examined. It was V. V. Smirnov and P. P. Potapov In its USSR Rept: Space found that at fractionated local irraditions the clinical symptom- Biol. and Aerospace Med.. Vol. 15, No. 6. Nov. - Dec. 1981 complex of radiation sickness was identifical to that seen as a (JPRS-79849) 12 Jan. 1982 p 101-103 refs Transl. into result of total-body irradiation. During head irradiation the major ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15. symptom was headache and during stomach irradiation nausea. no. 6. Nov. - Dec. 1981 p 69-71 The severity level of radiation damage measured with respect to the clinical symptom-complex as a whole with the aid of the Avail: NTIS HC A08/MF A01 bioinformation model was similar during irradiations of the head The activity of cytochrome oxidase in th* liver, skeletal and stomach, much higher during irradiation of the chest. During muscles, kidneys, brain and lungs of 56 white rats decreased head and stomach irradiations the severity level of radiation on days 15 and 60 of the hypokinetic study. The activity of damage was proportional to the efficient dose. During chest succinate dehydrogenase significantly lowered in the brain and irradiation there was no correlation between the severity level slightly diminished in the lungs and skeletal muscles on the and the exposure to doses of 210 rad. Author same days. The activity of succinate dehydrogenase in the liver increased on the 90th hypokinetic day. Author N82-16727$ Joint Publications Research Service. Arlington, Va. N82-16724$ Joint Publications Research Service, Arlington, METHOD OF RECORDING ROTATORY EYE REFLEXES Va. LIPID SPECTRUM OF THE MYOCARDIUM OF WHITE RATS M. M. Levashov and A. V. Dmitriyev In its USSR Rept.: Space EXPOSED TO HYPOXIC HYPOXIA Biol. and Aerospace Med., Vol. 15. No. 6. Nov. - Dec. 1981 S. A. Sergeyev and G. A. Gribanov In its USSR Rept.: Space (JPRS-79849) 12 Jan. 1982 p 119-122 refs Transl. into Biol. and Aerospace Med.. Vol. 15, No. 6, Nov. - Dec. 1981 ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15. (JPRS-79849) 12 Jan. 1982 p 104-108 refs Transl. into no. 6. Nov. - Dec 1981 p 80-82 ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15. no. 6. Nov. - Dec. 1981 p 71-74 Avail: NTIS HC A08/MF A01 A method of recording rotatory eye reflexes in real time Avail: NTIS HC A08/MF A01 using polarized light is described. When a beam of light going By a modified microthin-layer chromatography the total lipid to the photodetector is passed successively through two polarizers, spectrum of the cardiac muscle of white rats exposed to acute illumination of the detector will depend on reciprocal orientation oxygen deficiency in an altitude chamber was investigated. It of polarization planes. Reciprocal rotation of polarization planes was found that the content of total lipids. phospholipids. free alters illumination proportionally to the cosine of angle of rotation. cholesterol, free fatty acids and triglycerides decreased during When the planes are parallel (0 degree angle), illumination is at acute hypoxia. The exposure induced changes in the amount of a maximum, and when one of the planes is rotated 90 degrees glycerophosphatids. phosphatid acids and polyglycerophosphatids in relation to the other, it is minimal. A miniature photoresistor whose content diminished significantly. The concentration of is used as a 'detector, and it is covered with polarizing layer. phosphatidyl serines and phosphatidyl ethanol amines lowered The detector is placed on the anesthetized eyeball with suction to a lesser extent while that of sphyngomyelins increased. Acute cups. The light source and miniaturized amplifier unit were oxygen deficiency accelerates the release of inorganic phosphate assembled on a mask worn over the subject's head. R.J.F.

126 N82-16735

N82-16728# Joint Publications Research Service, Arlington. five intact animals of the same ages and weight served as a Va. control. Nervous elements were demonstrated by means of silver ELECTRODE UNIT FOR TESTING HUMAN H REFLEX nitrate impregnation according to Bielschowsky, in various V. I. Zborovskaya and E. A. Skiba In its USSR Rept.: Space modifications, followed by gold-plating and additional staining Biol. and Aerospace Med.. Vol. 15. No. 6. Nov. - Dec. 1981 with nuclear-plasma stains. R.J.F. (JPRS-79849) 12 Jan. 1982 p 123-124 refs Transl. into ENGLISH from Kosm. Biol. Aviakosm. Med. (Moscow), v. 15. no. 6. Nov. - Dec. 1981 p 82-83 N82-16732*# Electro-Optics Consultants. Inc.. Huntsville. Ala. DETECTION OF AMBLYOPIA UTILIZING GENERATED RETINAL REFLEXES Final Report Avail: NTIS HC A08/MF A01 J. H. Kerr and S. H. Hay 13 Nov. 1981 52 p refs Use of a method of recording H reflexes that makes it possible (Contract NAS8-33819) to test the level of reflex activity of spinal motoneurons at rest (NASA-CR-161944: Rept-5153-33819) Avail: NTIS and during movement, as well as to make qualitative and HC A04/MF A01 CSCL 06E quantitative evaluations of various supraspinal and afferent factors Investigation confirmed that GRR images can be consistently is discussed. An electrode unit for electrostimulation of peripheral obtained and that these images contain information required to nerves or muscles was made. It has 6 electrodes 8-10 mm in detect the optical inequality of one eye compared to the fellow diameter, which are mounted on en elastic dielectric plate. eye. Digital analyses, electro-optical analyses, and trained Rounded corners of the plate protect the skin from trauma when observers were used to evaluate the GRR images. Two and the electrode unit is secured firmly. The electrode unit is secured three dimensional plots were made from the digital analyses firmly to the region of the popliteal fossa, connected to the results. These plotted data greatly enhanced the GRR image electrosimulator through a selector which connects the unit content, and it was possible for nontrained observers to correctly electrodes one after the other. The stimulation point is determined from the nature and magnitude of responses elicited in the identify normal vs abnormal ocular status by viewing the plots. muscle innervated by the stimulated nerve. R.J.F. Based upon the criteria of detecting equality or inequality of ocular status of a person's eyes, the trained observer correctly identified the ocular status of 90% of the 232 persons who N82-16729# Joint Publications Research Service, Arlington, participated in this program. T.M. Va. COMPARATIVE ANTIHYPOXIC EFFICACY OF PRESSURE N82-16733# Civil Aeromedical Inst., Oklahoma City, Okla. CHAMBER CONDITIONING AND FASTING OF MAN A. Yu. Katkov, Ye. A. Kovalenko, R. N. Chabdarova, G. A. Davydov. FATIGUE IN FLIGHT INSPECTION FIELD OFFICE (FIFO) S. A, Vtoryy, and N. M. Utkina In its USSR Rept: Space Biol. FLIGHT CREWS and Aerospace Med., Vol. 15, No. 6, Nov. - Dec. 1981 C. E. Melton, J. M. McKenzie, S. M. Wicks, and J. T. Saldivar Apr. 1981 51 p refs (JPRS-79849) 12 Jan. 1982 p 125-128 refs Transl. into ENGLISH from Kosm. Biol. Aviakosm Med (Moscow), v. 15. (AD-A106791: FAA-AM-81-13) Avail: NTIS HC A04/MF A01 CSCL 06/19 no. 6, Nov. - Dec. 1981 p 84-86 Studies related to FIFO aircrew stress and fatigue were carried Avail: NTIS HC A08/MF A01 out at seven FIFO's in the Continental U.S. Forty-one men served Two theoretically possible means of enhancing man's as subjects and all crew positions were presented. Each crewmember was studied during flight activities and during office resistance to rapidly increasing hypoxia. pressure chamber based activities. Generally, crews were in travel status during conditioning and fasting, are studied Eleven essentially healthy flight inspection activities and away from the office for 5 d. men were divided into two groups. The first group of subjects was submitted to 10-day pulsed pressure chamber conditioning. Crewmembers completed fatigue checklists before and after each duty on every workday. Urine specimens were collected that The second group of subjects spent 14 days on a total fast, without limiting water intake. Endurance of hypoxia in the first represented the night sleep period and the work period; they group was determined before pressure chamber conditioning and were analyzed for 17 ketogenic steroids, epinephrine, and immediately after it, and in the second group before the fast norepinephrine, and values were expressed as weight per hundred and on the 14th day of food deprivation. The subject was raised milligrams of urinary creatinine. Ambulatory electrocardiograms continuously in the chamber at the rate of 20 m/s at rest, to were recorded for determination of heart rate (HR) during work. maximum tolerance of altitude. The subject was raised again at The data indicate that office work is distinctly less fatiguing the same speed 30 minutes after descending to 'Earth', but than flight work. This finding is supported by the HR data that with concurrent performance of exercise on a bicycle ergometer indicate a lower workload in the office than in flight. The statement constituting 200 kg-m/minutes In both cases, the subject had is commonly made by crewmembers that office work is more to report the current 'altitude when so instructed. In the course fatiguing than flight work. It is probable that such statements of the test, a continuous recording of oxygen tension in the are based on work preference rather than work level, Some skin of the left forearm was made by the polarographic method. crewmembers at Oklahoma City, Atlanta, Los Angeles, and At normal barometric pressure, body weight, gas exchange, Battle Creek show severe fatigue associated with flight work. morphological and gas composition, and acid-base equilibrium GRA of capillary blood was determined. R.J.F. N82-16734# Desmatics. Inc., State College. Pa. N82-16730# Joint Publications Research Service. Arlington, ACCELERATION MEASURES AND MOTION SICKNESS Va. INCIDENCE CONDITION OF MENINGEAL NERVOUS SYSTEM DURING Carl A. Mauro and Dennis E. Smith Nov. 1981 24 p refs REPEATED EXPOSURE TO TRANSVERSE ACCELERA- Presented at the Intern. Workshop on Res. Methods in Human TIONS Motion and Vibration Studies, New Orleans 16-18 Sep. 1981 G. A. Konstantinovskiy In its USSR Rept.: Space Biol. and (Contract N00014-79-C-0128; NR Proj. 207-037) Aerospace Med.. Vol. 15. No. 6. Nov. - Dec 1981 (JPRS-79849) (AD-A107996: TR-112-10) Avail: NTIS HC A02/MF A01 12 Jan. 1982 p 129-132 refs Transl. into ENGLISH from CSCL 06/19 Kosm. Biol. Aviakosm. Med. (Moscow), v. 15, no. 6, Nov. - An important aspect of motion sickness research is to establish Dec. 1981 p 86-88 quantitative relationships between sickness incidence and various parameters of the motions that induce sickness. At present, Avail: NTIS HC A08/MF A01 however, only wholebody vertical sinusoidal motion has been The nerve elements of the dura and pia mater of the brain studied to any reasonable degree. The purpose of this report is of 19 puberal cats weighing 2 to 3 kg were examined following to examine the predictive utility of six different characterizations repeated exposure to transverse accelerations (chest-back) for of sinusoidal motion and to investigate their possible extension 20 minutes at 24-hour intervals, for 6 days. A force of 8 units to dual frequency motion. Author (GRA) with a gradient of acceleration build-up and decline of 0.5 to 0.4 unit/s was generated on a centrifuge with, a 5 m arm, N82-16735# Oak Ridge National Lab., Tenn. Chemical Effects equipped with specially molded containers, in which the animals Information Center. were immobilized in their physiological position. The cats were CHEMICALS IDENTIFIED IN HUMAN BIOLOGICAL sacrificed using ether fumes at different times after the MEDIA experiments: 1, 3, 7. 30 and 90 days, which enabled experimenters M. Virginia Cone and Cindy Stroup (EPA) 1981 6 p refs to track the dynamics of recovery processes. The meninges of Presented at 2nd EPA/NCI Ann. Collaborative Workshop Environ.

127 N82-16736

and Occupational Cancer Studies. Rockville, Md.. 9-11 Sep. Shanta P. Kerkar and William C. Howell Aug. 1981 45 p 1981 refs (Contract W-7405-eng-26) (Contract N00014-78-C-0555: NR Proj. 197-050) (OE81-030813: CONF-810959-1) Avail: NTIS (AD-A106143: TR-81-2) Avail: NTIS HC A03/MF A01 CSCL HC A02/MF A01 05/1 Sources of data are from the world literature, retrospective Previous investigations by the authors have shown that to 1974. Information from approximately 1500 documents is in judgments of frequency or probability have a facilitatory influence the data base at the present time. The data base contains on subsequent predictive choice performance. The present study information on 750 chemicals. Approximately 10% of the total examined both these judgement processes more closely in an documents in the file concerned pesticides; 30% drugs: and attempt to understand how they affect choices. Five groups of 40% metals. The remaining 20% were about other substances, subjects served as emergency vehicle dispatchers for a hypothetical including industrial chemicals and organics which are of interest city. The experimental design involved a 2x2 factorial combination to NCI and EPA. T.M. of response set and estimation task. More specifically, response set. defined as expectation of a frequency or probability response N82-16736# Michigan Univ.. Ann Arbor. Highway Safety requirement, was crossed with actual response requirement, either Research Inst. frequency or probability estimation, in a between-groups design. REVIEW OF LITERATURE AND REGULATION RELATING Author (GRA) TO THORACIC IMPACT TOLERANCE AND INJURY CRITE- RIA Final Report. Jul. 1980-Jun. 1981 N82-16740# RAND Corp., Santa Monica. Calif. Robert L. Hess. Kathleen Weber, and John W. Melvm Jul. AN ANALYSIS OF COGNITIVE MAPPING SKILL Interim 1981 281 p refs Sponsored in part by Motor Vehicle Report Manufacturers Association Perry W. Thorndyke and Sarah E. Goldin Mar. 1981 66 p (PB82-108697: UM-HSRI-81-38) Avail: NTIS refs HC A13/MF A01 CSCL 06S (Contract MDA903-79-C-0549) The technical and scientific literature dealing with thoracic (AD-A106145: RAND/N-1664-ARMY) Avail: NTIS injury to or within the rib cage, from blunt loading is reviewed. HC A04/MF A01 CSCL 08/2 The history of the development of associated Federal Motor Vehicle Compares the performance of good and poor cognitive Safety Standards is reviewed from the aspect of its relationship mappers on a variety of spatial knowledge acquisition and to the history of development of the research information. Field judgment tasks. Cognitive mapping skill was assessed by case data from car-to-car and car-to-tree/pole crashes has been measuring subjects' knowledge of a highly overlearned environ- examined and summarized. This study suggests that the laboratory ment, their home community. Subjects categorized as good or research has not adequately covered the principal variables found poor cognitive mappers participated in a series of experiments to exist in actual injury cases. Specifically more research attention that examined learning a novel environment from navigation should be given to the shape of the impactor, to the loading experience, map learning, map using and map interpretation, location and directory, and to injuries in the contusion and/or spatial judgments based on a memorized map, and navigation laceration family. Correspondingly, the accident investigation in a novel environment based on a memorized map. Good mappers process needs to be more sensitive to occupant/vehicle interior performed more accurately than poor mappers in learning a novel interaction variables so that laboratory research can be properly environment, learning maps, and making spatial judgments based guided. GRA on a memorized map. Map using, map interpretation, and navigation tasks did not distinguish good from poor mappers. N82-16737# Applied Physics Lab.. Johns Hopkins Univ.. Laurel. We conclude that, relative to poor mappers, good cognitive Md. mappers are better able to encode and retain spatial information HUMAN REACTIONS TO ELF ELECTRIC AND MAGNETIC in memory and to mentally transform or manipulate spatial FIELDS: AN ANNOTATED BIBLIOGRAPHY OF CURRENT information in order to make spatial judgements, and we LITERATURE hypothesize that differences in spatial visualization and visual J. Patrick Reilly Jul. 1981 42 p memory abilities may underlie these variations in task perfor- (PB82-102567; PPSP/JHU/PPSE-T-20) Avail: NTIS mance. Author (GRA) HC A03/MF A01 CSCL 06P This annotated bibliography lists current literature (since 1960) N82-16741# RAND Corp.. Santa Monica. Calif. which applies to human reactions to electric and magnetic fields ABILITY DIFFERENCES AND COGNITIVE MAPPING SKILL from 10 Hz to 100 Hz, with an emphasis on power frequency Interim Report fields. This includes direct experimental work with humans, Perry W. Thorndyke and Sarah E. Goldin Mar. 1981 66 p epidemiological studies, work which uses animal studies to draw refs interferences about human reactions, studies concerning human (Contract MDA903-79-C-0549) dosimetry, and works which discuss means for human protec- (AD-A106389; RAND/N-1667-Army) Avail: NTIS tion. GRA HC A04/MF A01 CSCL 08/2 Compares good and poor cognitive mappers on a number N82-16738$ Centra Informazioni Studi Esperienze, Milan (Italy). of individual difference variables potentially related to cognitive IN VIVO RECORDING OF BLOOD VELOCITY PROFILES AND mapping skill: spatial abilities, visual/verbal processing style, STUDIES IN VITRO OF PROFILE ALTERATIONS INDUCED motivation, and experience. Good and poor mapper groups were BY KNOWN STENOSES given several assessment tests for each of these categories. M. Bassini. E. Gatti (Politecnico di Milano). T. Longo (Milan Comparisons of good and poor mappers' performance on these Univ.), G. M. Martinis, P. Pignoli (Milan Univ.), and P. L. Pizzolati tests indicated that only spatial abilities reliably distinguished 1980 36 p refs Presented at the 4th Intern. Conf. of the good mappers from poor mappers. Good cognitive mappers Cardiovascular System Dyn. Soc. Peripheral Vascular Hemodyn.: showed greater visualization ability, spatial orientation ability, Basic and Clinical Aspects. Miami. Fla . 12-15 Nov. 1980 visual memory, and field independence. Other measures showed (PB81-244139: CISE-1655) Avail. NTIS HC A03/MF A01 no between-group differences. It is concluded that spatial ability CSCL 068 is a major determinant or cognitive mapping skill and that spatial Measurements were obtained with a pulsed ultrasonic ability tests can be used to select personnel for tasks requiring instrument based on the analysis of the cross-correlation function navigation, orientation, and spatial judgment skills. Author (GRA) of blood diffused echoes. The alterations and velocity in the time domain were studied in vitro as function of the distance between stenosis and measuring point, and position of the sample N82-16742*# Minnesota Univ.. St. Paul. Dept. of Food Science volume along the diameter. These studies may be useful for a and Nutrition. better comprehension of blood velocity measurements made with STORAGE STABILITY AND IMPROVEMENT OF INTERME- ultrasound equipments for clinical non-invasive diagnostic DIATE MOISTURE FOODS. PHASE 5 Final Report. 1 Oct. purposes. T.M. 1976 - 28 Feb. 1978 Theodore P. Labura 28 Feb. 1978 399 p refs N82-16739# Rice Univ., Houston. Tex. Dept. of Psychology. (Contract NAS9-12560) CHOOSING AMONG ALTERNATIVES WITH UNCERTAIN (NASA-CR-167503) Avail: NTIS HC A17/MF A01 CSCL OUTCOMES: EFFECT OF PRIOR CURING AND ESTIMA- 06H TION REQUIREMENTS A method for measuring water binding la sub w) in gels

128 N82-17811 which was developed and applied to various macromolecular PROBLEMS Final Technical Report. Apr. 1979 - Sep. 1980 geling agents in order to elucidate their mechanism of water Larry Butterbaugh, Debra Warner, Peter Lovering, and Sam Herron binding was confirmed with concurrent studies using NMR. X-ray Wright-Patterson AFB AFWAL Aug. 1981 186 p refs diffraction and dye diffusion. The vapor pressure manometric (Contract F33615-78-C-3614; AF Proj. 2403) method for a sub w was further refined to give a sub w to + (AD-A107758; AFWAL-TR-81-3011) Avail: NTIS or - 0.0001 units, and a new fiber cup procedure was tested HC 09/MF A01 CSCL 01/3 against it. The effectiveness of low a sub w on inhibiting potential Five hundred and seventy three USAF pilots responded to a toxin production by S. aureus was demonstrated. In addition, survey which had as its objective the identification of operational, ethanol. was shown to be an effective antimicrobial agent at crew station design related causes of high pilot workloads. The low concentration in lowered a sub w systems. The results of a survey consisted of mailed survey forms and personal interviews study of vitamin C loss during processing at high temperature structured to conform with the critical incident technique of (60-150C) show a change to zero order kinetics due to poor collecting user-provided data. The survey canvassed over 50 USAF oxygen solubility. Steady state temperature data can be used to organizations in collecting data for more than 30 currently flown predict losses during unsteady state processing. Non-enzymatic USAF aircraft types. The role control/display design, crew station browning can be reduced at higher process temperature if design, and equipment malfunctions play in contributing to cockpit residence time decreases. A shelf stable IMF processed cheese workload is unique to each aircraft. Other factors, such as weather, food was developed and shown to be acceptable in storage flight schedules, and mission phase appear to contribute to cockpit A R.H. workloads in most all the aircraft surveyed. Further, the reported situations, or critical incidents, indicate that high workloads result from the simultaneous occurrence or existence of several causes. N82-16743*# National Aeronautics and Space Administration. For example, a high workload situation reported for the FB-111 Lewis Research Center. Cleveland, Ohio. consisted of an equipment failure while flying the low level A HYDRODYNAMIC MODEL OF AN OUTER HAIR CELL penetration portion of a mission at night. All data collected has Bo O. Jacobson 1982 14 p refs To be presented at the been catalogued for the establishment of an information base, 19th Ann. Northeast Bioengr. Conf, Hanover, New Hampshire. and available for future use in conjunction with aircraft develop- 15-16 Mar. 1982; sponsored by the Thayer School of Engineering ment programs or modernization/retrofit oroqrams. Author (GRA) Dartmouth Med. School. IEEE. ASME. and the American Society for Engineering Education (NASA-TM-82773; E-1098) Avail: NTIS HC A02/MF A01 N82-17239# Joint Publications Research Service, Arlington. CSCL 06P Va. On the model it is possible to measure the force and the STATUS OF SPACE BIOMEDICAL PROGRAMS force direction for each individual hair as a function of the flow Avadalik Ignatyevich Burnazyan In its USSR Rept.: Space, direction and velocity. Measurements were made at the man No. 14 (JPRS-79711) 22 Dec. 1981 p 29-33 Transl. into flow velocity .01 m/s, which is equivalent to a flow velocity in ENGLISH from Pravda (Moscow), 15 Jun. 1981 p3 the real ear of about 1 micrometer/s. The kinematic viscosity of the liquid used in the model was 10.000 times higher than Avail: NTIS HC A05/MF A01 the viscosity of perilymph to attain hydrodynamic equality. Two Four specialized biological satellites in the Cosmos series different, geometries for the sterocilia pattern were tested First conducted research to study the mechanisms of the effect of the force distribution for a W-shaped sterocilia pattern was weightlessness, the combined effect of weightlessness and ionizing recorded. This is the sterocilia pattern found in all real ears. It radiation, and the biological effect of artificial gravity on living is found that the forces acting on the hairs are very regular and systems. Devices developed included: a centrifuge for the creation perpendicular to the legs of the W when the flow is directed of artificial gravity, an irradiator, instruments for rowing and fixing from the outside of the W. When the flow is reversed, the plant organisms. The cardiovascular system as studied during forces are not reversed, but are much more irregular. This can the so-called period of acute adaptation to weightlessness (the eventually explain the half wave rectification of the nerve first 7 days of a flight). Special features of central and peripheral signals. As a second experiment, the force distribution for a blood circulation and blood circulation in the brain were studied. V-shaped sterocilia pattern was recorded. Here the forces were A ballistic cardiography method judged the contractive function irregular both when the flow was directed into the V and when of the evaluated dynamics of blood flow, and detected functional it was directed against the edge of the V. T.M. disruptions in the cardiovascular system. A densiotography method was also used. An 'Oxygen' physiological experiment was N82-16744# Lincoln Lab., Mass. Inst. of Tech., Lexington. performed utilizing a portable 'Oxymeter' instrument to determine THE EFFECTS OF MICROPHONES AND FACEMASKS ON oxygen pressure level changes and its consumption by body LPC VOCODER PERFORMANCE tissues. Radiation safety tests were also conducted using Elliot Singer 25 Sep. 1981 26 p refs thermoluminescent dosimeters. Results of these tests are given. (Contract F19628-80-C-0002; AF Proj. 2283) A center for processing of the data and hygienic and biophysical (AD-A107908: TR-584: ESD-TR-81-277) Avail: NTIS information that serves as a consultative-prognostic group is also described. M.D.K. HC A03/MF A01 CSCL 05/8 The effects of oxygen facemasks and noise cancelling microphones on LPC vocoder performance were analyzed and evaluated. N82-17810 Rush Univ.. Chicago. III. Likely sources of potential vocoder performance degradation in- SOME MECHANISMS OF CALCIUM TRANSPORT BY THE cluded the non-ideal frequency response characteristics of the mi- CARDIAC SARCOLEMMA Ph.D. The«i» crophone, the acoustic alterations of the speech waveform due to Ronald F. Ledvora 1981 80 p the addition of the facemask cavity, and the presence of breath Avail: Univ. Microfilms Order No. 8124733 noise imposed by the'close-talking requirement. It is shown that Purified sarcolemmal membrane vesicles were prepared from the presence of the facemask produces a vowel-dependent frozen dog heart ventricles by a combination of differential and reduction in the bandwidths of the upper speech formants. In sucrose step gradient ultracentrifugation. The Ca ++ flux addition, the low frequency emphasis normally associated with measurements were made using a rapid filtration technique. About small enclosures is shown to occur when a pressure microphone 80 percent of the Ca( + + ) accumulated by Na(+)/Ca(+ + ) is employed for transduction. Noise cancelling microphones, which exchange or Ca(++ )/Ca(++ ) exchange could be released as are sensitive to the pressure gradient, do not exhibit this effect. free Ca(+ + ), while up to 20 percent was probably bound. The Finally, an acoustic tube model of the vocal tract and facemask mechanisms for Na( +)/Ca( + +) exchange and Ca( + +)/Ca( + +) is presented which predicts the absence of spurious resonances exchange are located in the sarcolemmal membrane of cardiac within the frequency band of typical narrowband vocoders. muscle cells. Both processes transport freely-exchangeable Evidence supporting these assertions is presented based on Ca(++) across the membrane. Electrogenic Na(+)/Ca(+ + ) observed vowel spectra. Evaluations performed using Diagnostic exchange may influence the excitability of the cardiac muscle Rhyme Tests indicate that the presence of the oxygen facemask cell. Both processes are probably carrier mediated transport and noise cancelling microphone does not result in a significant mechanisms, although not by the same carrier. Both Na( + )/ increase in the LPC vocoder processing loss. Author (GRA) Ca(++) exchange and Ca( + + )/Ca( + ) exchange probably play important roles as Ca( + +1 homeostatic mechanisms in the cardiac muscle cell. Dissert. Abstr. N82-16745# Bunker-Ramo Corp.. Westlake Village. Calif. Electronics Systems Div. N82-17811 Illinois Univ. at Urbana-Champaign. PILOT WORKLOAD: A SURVEY OF OPERATIONAL THE STRUCTURE AND FUNCTION OF CHLOROPHYLL

129 N82-17812

PROTEINS IN PHOTOSYSTEM 1 AND THE LIGHT HAR- Sep. - Oct. 1981 pJ7-20 VESTING COMPLEX OF PHOTOSYSTEM 2 Ph.D. Thesis Avail: NTIS HC A07/MF A01 John Emerson Mullet 1980 150 p The advanced space diets of three prime crews who made Avail: Univ. Microfilms Order No. 8127654 96-. 140- and 175-day flights aboard Salyut-6 are described. It The functional units of chloroplast membranes which mediate is concluded that the diets facilitated maintenance of a good photosynthetic electron transport from water to NADP are nutrient status, high work capacity and normal health condition. structurally organized into integral complexes. Two of these J.M.S. membrane-bound complexes, Photosystem I (PSD and Pho- tosystem II (PS II). consist in part of chlorophyll proteins. N82-17816# Joint Publications Research Service. Arlington. Photosystem I complexes were isolated by a technique which Va. allowed purification of PSI which retained characteristics attributed AMINO ACID METABOLISM DURING PROLONGED to PS I in vivo. The purified PS I complexes were further INTAKE OF DEHYDRATED FOODS AND SIMULATION OF fractionated by detergent treatment and PS I complexes which SOME SPACE FLIGHT FACTORS were depleted of chlorophyll proteins were isolated. The major V. P. Bychkov, I. I. Borodulina. and T. F. Vlasova In its USSR chlorophyll-protein of chloroplast membranes which is structurally Rept.: Space Biol. and Aerospace Med., V. 15, No. 5. Sep. - organizing into light harvesting complexes associated with PS II Oct. 1981 (JPRS-79346) 2 Nov. 1981 p 26-29 refs Transl. was isolated and characterized and its role in thylakoid adhesion into ENGLISH from Kosm. Biol. Aviakosmich. Med. (USSR).v. 15. tested. The chlorophyll-protein complex, termed LHC-II, were no. 5. Sep. Oct. 1981 p 21-23 incorporated into lipid vesicles: this preparation was used to demonstrate the involvement of LHC-II in cross-membrane Avail: NTIS HC A07/MF A01 adhesion between thylakoid membranes. Dissert. Absrt. Forty-two healthy volunteers, aged 19 to 49, participated in three bed rest studies of 69 to 180 days in duration. The test N82-17812# Joint Publications Research Service, Arlington. subjects were kept on the diet consisting of dehydrated foods: Va. fresh, stored for up to 2 years, and exposed to proton irradiation USSR REPORT: SPACE BIOLOGY AND AEROSPACE at a dose of 24.000 rad. Metabolism of amino acids was MEDICINE. VOL. 15. NO. 5. SEP. - OCT. 1981 investigated under these conditions. It was concluded that during 0. G. Gazenko, ed 2 Nov. 1981 146 p refs Transl. into prolonged storage and irradiation proteins of dehydrated foods ENGLISH of Kosm. Biol. Aviakosmich. Med. (USSR), v. 15. retained their biological value. This allows their use in long term no, 5, Sep. - Oct. 1981 space flights. Author UPRS-79346) Avail: NTIS HC A07/MF A01 The varied effects of space flight factors on the human body are addressed. Results of simulation studies as well as data N82-17817# Joint Publications Research Service. Arlington. gathered in-flight are presented. Experimental studies performed Va. on rats flown onboard various Cosmos satellites are also included. EFFECT OF SPACE FLIGHTS OF DIFFERENT DURATION ON ENERGY METABOLISM OF HUMAN ERYTHROCYTES

N82-17813# Joint Publications Research Service, Arlington, A. S. Ushakov, S. M. lyanova. S. S. Brantqva, and 0. I. Labetskaya Va, In its USSR Rept.: Space Biol. and Aerospace Med.. V. 15. No. 5. Sep. - Oct. 1981 (JPRS-79346) 2 Nov. 1981 p 30-34 IN-FLIGHT DIETS AND QUANTITATIVE ADEQUACY refs Transl. into ENGLISH from Kosm. Biol. Aviakosmich. Med. THEREOF TO PILOT EXPENDITURE I. G. Popov In its USSR Rept.: Space Biol. and Aerospace (USSR), v. 15, no. 5, Sep. - Oct. 1981 p 23-27 Med.. V. 15. No. 5, Sep. - Oct. 1981 (JPRS-79346) 2 Nov. Avail: NTIS HC A07/MF A01 1981 p 1-13 refs Transl. into English from Kosm. Biol. The energy metabolism of red blood cells of cosmonauts Aviakosmich. Med. (USSR), v. 15. no. 5. Sep. - Oct. 1981 p 4-14 was investigated before and after flights of varying duration. Certain changes in red blood metabolism were found after Avail: NTIS HC A07/MF A01 prolonged space flights. Author Nutrition of aircraft crews in prolonged flights is discussed. Meal arrangements in flights of up to 4 hours, physiological- hygienic requirements to flight diets and, on this basis, possible N82-17818# Joint Publications Research Service, Arlington. improvement of crew nutrition through a better utilization of Va. meals on the ground are addressed. The Soviet and foreign PREVENTION OF STAPHYLOCOCCAL INFECTIONS data on pilot energy expenditures and caloric value of diets in DURING SPACE FLIGHTS flights over 4 hours are reviewed with emphasis on potential S. N. Zaloguyev, A. N. Viktorov. V. P. Gorshkov. T. Yu Norkina, development of excessive food intake with symptoms of acute and M. M. Shinkareva In its USSR Rept.: Space Biol. and overeating in prolonged flights. J.M.S. Aerospace Med., V. 15. No. 5. Sep. - Oct. 1981 (JPRS-79346) 2 Nov. 1981 p 35-38 refs Transl. into ENGLISH from Kosm. N82-17814| Joint Publications Research Service. Arlington. Biol. Aviakosmich. Med. (USSR), v. 15, no. 5. Sep. - Oct. 1981 Va. p 27-29 EFFECT OF STATIONARY MAGNETIC FIELD ON THE Avail: NTIS HC A07/MF A01 ENDOCRINE SYSTEM The incidence of carriers of photogenic staphylococci among Ye. A. Zagorskaya In its USSR Rept.: Space Biol. and Aerospace cosmonauts and candidates (applicants) for positions of crew Med.. V. 15. No. 5, Sep. - Oct. 1981 (JPRS-79346) 2 Nov. members in spacecraft was investigated. The staphylococcal flora 1981 p 14-20 refs Transl. into ENGLISH from Kosm. Biol. of carriers were assessed while they participate in space flights Aviakosmich. Med. (USSR), v, 15. no. 5, Sep. - Oct. 1981 varying in duration. Samples of microflora were taken from people p 14-17 in their ordinary habitat by means of cotton swabs. To collect Avail: NTIS HC A07/MF A01 samples of miroflora from cosmonauts while in the cabin of a It is indicated that endocrine glands react to the constant spacecraft, specially developed test tubes containing a preservative magnetic field (CMF). The phasic pattern of the hypophyseal- were used. The material was analyzed under laboratory conditions adrenal reaction and GMF effects on the sympathoadrenal system after delivering specimens to .Earth. Pathogenic staphylococci and thyroid are discussed. The potential therapeutic applications (Staph. aureus) were identified by testing the capacity to of the CMF is addressed with emphasis on the fact that most decompose mannitol under anaerobic conditions, production of morphological data available need biochemical support. J.M.S. the enzymes, coagulase and lecithinase. as well as on the basis of presence and intensity of toxin production, in the isolated N82-17815# Joint Publications Research Service. Arlington, cultures. The strains of pathogenic staphylococci were submitted to phage typing using the international set of staphylococcal Va. DIET OF CREWS OF THREE MAIN EXPEDITIONS ABOARD bacteriophages J.M.S. SALYUT-6 ORBITAL STATION V. P. Bychkov. S. Kalandarov. M. V. Markaryan. N. 0. Radchenko, N82-17819# Joint Publications Research Service, Arlington, K. A. Stepchkov. and M. L. Frumkin In its USSR Rept.: Space Va. Biol. and Aerospace Med.. V. 15. No. 5, Sep. - Oct. 1981 HUMAN ADRENOSYMPATHETIC SYSTEM DURING (JPRS-79346) 2 Nov. 1981 p 21-25 refs Transl. into ENGLISH IMMERSION IN WATER from Kosm. Biol. Aviakosmich. Med. (USSR), v. 15. no. 5. N. A. Davydova, R. A. Tigranyan. and Ye. B. Shulzhenko In its

130 N82-17827

USSR Rept.: Space Biol. and Aerospace Med., V. 15. No. 5. V. P. Bychkov and V. A. Korshunova In its USSR Rept.: Space Sep. - Oct. 1981 (JPRS-79346) 2 Nov. 1981 p 39-44 refs Biol. and Aerospace Med.. V. 15. No. 5. Sep. - Oct. 1981 Transl. into ENGLISH from Kosm. Biol. Aviakosmich. Med. (USSR), (JPRS-79346) 2 Nov. 1981 p 63-67 refs Transl. into ENGLISH v. 15. no. 5. Sep. - Oct. 1981 p 30-34 from Kosm. Biol. Aviakosmich. Med. (USSR), v. 15. no. 5. Sep. - Oct. 1981 p 46-49 Avail: NTIS HC A07/MF A01 The activity of the sympathoadrenal system (SAS) of Avail: NTIS HC A07/MF A01 12 volunteers exposed to water immersion for 7 days was studied. Renal excretion of ascorbic acid, thiamin. and 4-pyridoxic Before and after water immersion, six of the test subjects were acid was studied in 18 test subjects exposed for 182 days to exposed to acceleration of +3 Gz for 15 min. It was demonstrated head-down tilt. Two groups of subjects (6 subjects in each) that water immersion increased the hormonal activity and performed exercises of different work load and the third control decreased the transmitter activity of the SAS. Exposure to group was exposed to hypokinesia as such. It is shown that acceleration stimulated the SAS. thus increasing immersion exercises produced a beneficial effect on vitamin metabolism. It tolerance. Author is recommended to develop preliminary adaptation to the work load planned as a countermeasure in real or simulated weightless- N82-17820# Joint Publications Research Service. Arlington, ness. Author Va. COMBINED EFFECT OF SIMULATED WEIGHTLESSNESS N82-17825# Joint Publications Research Service, Arlington. AND ACCELERATIONS ON ENERGY METABOLISM Va. ENZYMES JUGULAR. RIGHT ATRIAL PRESSURE AND CEREBRAL Ye. G. Vetrova. T. Ye. Drozdova, R. A. Tigranyan. and Ye. B. HEMODYNAMICS OF HEALTHY MAN SUBMITTED TO Shulzhenko In its USSR Rept.: Space Biol. and Aerospace POSTURAL TESTS Med.. V. 15. No. 5. Sep. - Oct. 1981 (JPRS-79346) 2 Nov. V. Ye. Katkov. V. V. Chestukhin. V. V. Rumyantsev. A. 2. Troshin, 1981 p 45-49 refs Transl. into ENGLISH from Kosm. Biol. and 0. Kh. Zybin In its USSR Rept.: Space Biol. and Aerospace Aviakosmich. Med. (USSR), v. 15. no. 5, Sep. - Oct. 1981 Med.. V 15, No. 5, Sep. - Oct. 1981 (JPRS-79346) 2 Nov. p 34-38 1981 p 6873 refs Transl. into ENGLISH from Kosm. Biol. Avail: NTIS HC A07/MF A01 Aviakosmich. Med. (USSR), v. 15, no. 5, Sep. - Oct. 1981 Exposure to simulated weightlessness (7 day water immersion p 49-53 and 7 day head-down tilt) caused a decrease in the activity of Avail: NTIS HC A07/MF A01 malate (MDH) and isocitrate dehydrogenase (ICDH), and creatine Ten test subjects were catheterized and exposed to head phosphokinase (CPK) at the expense of its MM isoform whereas up and head down tilts at 10, 30, and 75 deg for 5 min each the activity of alanine (ALT) and aspartate aminotransferase (AST) to measure blood pressure in the upper bulb of the internal and pattern of distribution of MDH isoforms remained unchanged. jugular vein and right atrium. Blood acid base equilibrium, Exposure to acceleration of +3 Gz before and after simulated hemoglobin content, and oxygen saturation were also deter- weightlessness revealed similar changes in the activity of MDH, mined. In the head up position at 75 deg the jugular pressure ICDH. ALT, AST and MDH cytoplasmic fractions. However, the decreased, remaining positive (2.8 mm Hg) in most cases, whereas higher increase in the enzyme activity after simulated weightless- the atrial pressure fell down to reach the subatmospheric level. ness may give evidence for a greater change in cell membrane In the head down position the jugular pressure increases in permeability during acceleration effects that followed simulated proportion to the tilt angle, amounting to 32.2 mm Hg at 75 deg weightlessness. Author the atrial pressure changed in a different fashion: in 7 cases it increased and in 3 cases decreased. Throughout the test the N82-17821# Joint Publications Research Service, Arlington. oxygen arteriovenous difference in the brain and the acid base Va. equilibrium in the outflowing blood remained essentially un- CARDIAC OUTPUT AND CARDIAC CYCLE PHASE changed. This reflects autoregulation of the cerebral blood flow STRUCTURE OF PILOTS DURING FLIGHTS and its adequacy to metabolic requirements. Author V. A. Degtyarev, V. S. Bednenko, A. B. Vasilyev, A. N. Kozlov, V. Ya. Kolyagin, and A. P. Yarunin In its USSR Rept.: Space Biol. and Aerospace Med., V. 15, No. 5. Sep. - Oct. 1981 N82-17826# Joint Publications Research Service. Arlington. (JPRS-79346) 2 Nov. 1981 p 50-54 refs Transl. into ENGLISH Va. from Kosm. Biol. Aviakosmich. Med. (USSR), v. 15, no. 5. EFFECTS OF EMBIENT PARAMETERS ON MAN Sep. -.Oct. 1981 p 38-41 R. M. Arslanova, I. Ye. Ganelina, V. Ye. Manoylov. L K. Sapozhkov, and S. K. Churina In its USSR Rept: Space Biol. and Aerospace Avail: NTIS HC A07/MF A01 Med., V. 15, No. 5, Sep - Oct. 1981 (JPRS-79346) 2 Nov Changes in cardiac output and systolic time intervals of pilots 1981 p 74-77 refs Transl into ENGLISH from Kosm. Biol. in-flight were examined by the Doppler ultrasound method. The Aviakosmich. Med. (USSR), v. 15, no. 5. Sep. - Oct. 1981 changes were related to the degree of complexity of different p 53-55 flight stages. It is recommended that the above parameters be Avail: NTIS HC A07/MF A01 monitored during flight training in order to standardize professional The effects of meteogeophysical parameters on the incidence loads. Author of cardiovascular disorders were studied. It is shown that geomagnetic activity has a negative effect on the incidence and that at certain seasons this effect is minimal Author N82-17822jjl Joint Publications Research Service. Arlington. Va. HUMAN LIPID METABOLISM DURING CONFINEMENT IN N82-17827# Joint Publications Research Service, Arlington, PRESSURE CHAMBER Va. V. P. Bychkov and 0. S. Khokhlova In its USSR Rept.: Space ANTIHYPOXIC EFFICACY OF INTERMITTENT MODE OF Biol. and Aerospace Med.. V. 15, No. 5. Sep. - Oct. 1981 PRESSURE CHAMBER CONDITIONING OF MAN (JPRS-79346) 2 Nov. 1981 p 55-58 refs Transl. into ENGLISH A. Yu. Katkov, Ye. A. Kovalenko, G. A. Davydov, R. N. Chabdarova. from Kosm. Biol. Aviakosmich. Med. (USSR), v. 15. no. 5, S. A. Vtoryy. A. P. Manik, Yu. A. Spasskiy, Yu. P. Starshinov, Sep. - Oct. 1981 p 41-43 and N. M. Utkina In its USSR Rept.: Space Biol. and Aerospace Med.. V. 15, No. 5, Sep. - Oct. 1981 (JPRS-79346) 2 Nov. Avail: NTIS HC A07/MF A01 1981 p 78-81 refs Transl. into ENGLISH from Kosm. Biol. The effect of prolonged enclosure, changed diet, atmosphere, Aviakosmich. Med. (USSR), v 15, no. 5, Sep. - Oct. 1981 and hypolinesia on lipid metabolism was investigated in 115 test p 56-58 subjects during 27 experimental runs. It was conducted that Avail: NTIS HC A07/MF A01 the changes in lipid metabolism occurred primarily due to reduced It is shown that a 10-day altitude chamber training in an work load. Author intermittent mode can increase the maximum altitude man tolerates from 8,400 to 9,500 m and maximum time of exposure N82-17824# Joint Publications Research Service. Arlington. to increasing hypoxia (from 5,000 m) from 37 to 49 min. The Va. antihypoxic effect of the above training persists for 10 days VITAMIN C. B SUB 1 AND B SUB 6 EXCRETION IN URINE after its completion, leading to a better oxygen supply to various DURING 182-DAY ANTIORTHOSTATIC HYPOKINESIA tissues. Author

131 N82-17828

N82-17828# Joint Publications Research Service, Arlington. pool of flight and synchronous rats were found. The changes Va. seem to be associated with the selective rate of incorporation INFORMATIVENESS OF ULTRASONIC DOPPLER CAR of free amino acids into the biosynthetic processes during acute DIOGRAPHY IN EVALUATION OF CORONARY CIRCULA- adaptation and with alterations in the protein synthesis rate. TION J.M.S. V. S. Bednenko. V. A. Degtyarev. A. N. Kozlov. N. N. Popov, and G. K. Chizhov In its USSR Rept.: Space Biol. and Aerospace N82-17832# Joint Publications Research Service. Arlington. Va. Med.. V. 15. No. 5. Sep. - Oct. 1981 (JPRS-79346) 2 Nov. 1981 p 82-86 refs Transl. into ENGLISH from Kosm. Biol. MYOCARDIAL PROTEIN FRACTIONS AND ENZYMATIC Aviakosmich. Med. (USSR), v. 15. no. 5. Sep. - Oct. 1981 ACTIVITY THEREOF IN EXPERIMENTAL RATS FLOWN ABOARD COSMOS 936 BIOSATELLITE p 58-61 Avail: NTIS HC A07/MF A01 R. A. Tigranyan. Ye. A. Nosova. Ye. V. Kolchina, N. A. Veresotskaya. The use of ultrasonic Doppler cartography (with respect to L. M. Kurkina. and N. S. Kolganova In its USSR Rept.: Space the integral values of the signal at systole) to determine efficient Biol. and Aerospace Med., V. 15. No. 5. Sep. - Oct. 1981 coronary circulation was investigated in acute dog experiments (JPRS-79346) 2 Nov. 1981 p 98-102 refs Transl. into (in comparison to the electromagnetic method) and in biophysical ENGLISH fom Kosm Biol. Aviakosmich. Med. (USSR), v. 15. models. On the basis of the comparative studies it is concluded no. 5. Sep. - Oct. 1981 p 68-71 that ultrasonic Ooppler cardiography can be applied to measure relative changes in the efficient coronary circulation. Author Avail: NTIS HC A07/MF A01 The effect of artificial gravity on protein fractions and their enzyme activity in the myocardium of rats flown onboard N82-17829# Joint Publications- Research Service. Arlington, Cosmos-936 was studied. In weightless rats the content of Va. sarcoplasmatic proteins increased at R + 0 and that of T fraction AGE RELATED DISTINCTIONS OF COSMONAUTS REGION- proteins decreased at R + 25. In centrifuged rats such changes AL HEMODYNAMICS were not seen. In centrifuged rats the enzyme activity of I. D. Vasilyeva. Kh. Kh. Yarullin. and V. I. Zhuyko In its USSR sarcoplasmatic proteins did not alter. In weightless rats ATPase Rept.: Space Biol. and Aerospace Med.. V. 15. No. 5. Sep. - activity of myosin decreased significantly, and in centrifuged rats Oct. 1981 (JPRS-79346) 2 Nov. 1981 p 82-90 ref Transl. it remained almost unchanged. Author into ENGLISH from Kosm. Biol. Aviakosmich. Med. (USSR), v. 15, no. 5. Sep. - Oct. 1981 p 61-64 N82-17833# Joint Publications Research Service. Arlington, Va. Avail: NTIS HC A07/MF A01 METABOLIC PROCESSIS IN RAT SKELETAL MUSCLES Hemodynamics of the large hemispheres of the brain, vertebral AFTER FLIGHT ABOARD COSMOS-936 basilar system, lungs and legs of 60 cosmonauts aged 30-37 and Ye A. Nosova. N. A. Veresotskaya. Ye. V. Kolchina, L. M. Kurkina. 38-47. were investigated rheographically. Measurements were R. A. Belitskaya. and R. A. Tigranyan In its USSR Rept.: Space made in the morning, under conditions of basal metabolism and Biol. and Aerospace Med., V. 15. No. 5. Sep. - Oct. 1981 in the daytime, before orthostatic tests. Comparison of hemody- (JPRS-79346) 2 Nov. 1981 p 103-107 refs Transl. into namic parameters recorded in the morning and at the daytime ENGLISH from Kosm. Biol. Aviakosmich. Med. (USSR), v. 15. and in the two age groups showed significant differences revealing no. 5. Sep. - Oct. 1981 p 71-75 the effects of different factors, first of all psychoemotional tension, on the vasomotor regulation, and greatest resistance of cerebral Avail: NTIS HC A07/MF A01 and pulmonary vascular systems of older cosmonauts to those The study of skeletal muscles of rats flown on Cosmos-936 effects. These investigations emphasize great importance of studies demonstrated different metabolic reactions in muscle fibers of of regional hemodynamics. especially rheoencephalography, not different function and type to weightlessness and Earth gravity. only before provocative tests but also under conditions of basal The data obtained gave evidence that artificial gravity may metabolism. Author considerably prevent metabolic changes in muscles developing in response to specific effects of weightlessness. Author N82-17830# Joint Publications Research Service. Arlington. N82-17834$ Joint Publications Research Service. Arlington. Va. Va. COMPARATIVE EVALUATION OF ANTIMICROBIAL ACTIVITY OF SOME ENZYMES OF CARBONHYDRATE ACTIVITY OF SOME URINE PRESERVATIVES METABOLISM IN RAT SKELETAL MUSCLES AFTER SPACE T. Ye. Lebedeva, I. V. Yakimova. N. M. Nazarov, and S. V. Chizhov FLIGHT In its USSR Rept.: Space Biol. and Aerospace Med.. V. 15, V. P. Nesterov. N. A. Veresotskaya. and R. A. Tigranyan In its No. 5. Sep. - Oct. 1981 (JPRS-79346) 2 Nov. 1981 p 91-94 USSR Rept.: Space Biol. and Aerospace Med.. V. 15. No. 5. refs Transl. into ENGLISH from Kosm. Biol. Aviakosmich. Med. Sep. - Oct. 1981 p 108-112 refs Transl. into ENGLISH from (USSR), v. 15. no. 5. Sep. - Oct. 1981 p 64-66 Kosm. Biol. Aviakosmich. Med. (USSR), v 15. no. 5, Sep. - Oct. 1981 p 75-78 Avail: NTIS HC A07/MF A01 Antiseptics were examined for their antimicrobial activity with Avail: NTIS HC A07/MF A01 respect to the microorganisms that are most likely to occur in Space flight factors did not influence activity of glycogen the urine subject to prolonged storage. Chlorine and iodine phosphorylase and adenylate cyclase in skeletal muscles of rats. containing compounds were found to have the highest antimicro- Activity of glucose-6-phosphate and 6-phosphogluconate dehy- bial activity combined with a wide spectrum of antimicrobial drogenases increased noticeably in the most active muscles action. The antimicrobial effect of these compounds was mostly (gastrocnemius and tibialis anterior muscles). Activation of expressed in regard to the typical representatives of urobacteria enzymes involved in the pentosephosphate pathway of glucose that actively hydrolyze urea to yield ammonia during prolonged conversion may be associated with compensatory processes storage of urine. Author induced by muscle changes due to diminished motor activity of animals in space flight. Author N82-17831# Joint Publications Research Service, Arlington, Va. N82-17835$ Joint Publications Research Service, Arlington. RAT AMINO ACID COMPOSITION AFTER FLIGHT ABOARD Va. COSMOS 1129 BIOS ATE LLITE ULTRASTRUCTURE OF BLOOD VESSELS AND MUSCLE T. F. Vlasova. Ye. B. Miroshnikova. T. A. Smirnova. and I. A. FIBERS OF RAT SKELETAL MUSCLES AFTER FLIGHTS Dmitriyeva In its USSR Rept.: Space Biol. and Aerospace ABOARD COSMOS 605 AND COSMOS 782 BIOSATEL- Med.. V. 15. No. 5, Sep. - Oct. 1981 (JPRS-79346) 2 Nov. LITES 1981 p 95-97 refs Transl. into ENGLISH from Kosm. Biol. Z. F. Davik and K. D. Rokhlenko In its USSR Rept.: Space Aviakosmich. Med. (USSR), v. 15. no. 5. Sep. - Oct. 1981 Biol. and Aerospace Med.. V. 15, No. 5. Sep. - Oct. 1981 p 66-68 (JPRS-79346) 2 Nov. 1981 p'113-118 refs Transl. into Avail: NTIS HC A07/MF A01 ENGLISH from Kosm. Biol. Aviakosmich. Med. (USSR), v. 15. Data concerning the amino acid pool of rats flown onboard no. 5. Sep. - Oct. 1981 p 78-83 Cosmos-1129 and exposed to the ground based synchronous experiment are presented. Certain changes in the amino acid Avail: NTIS HC A07/MF A01

132 N82-17843

Electron microscopy was used to study infrastructures of which the principal component of the Earth's magnetic field has the wall of blood vessels and muscle fibers of the red (soleus) an absolute minimum, providing a situation in which the gradient and mixed gastrocnemius) muscles of rats flown, on Cosmos of total intensity is zero in all directions, is also reported. T.M. 605 for 22.5 days and on Cosmos 782 for 195 days and sacrificed 4 to 6 hours. 48 hours and 25 to 27 days postflight. N82-17840$ Litton Bionetics. Inc.. Kensington. Md. It was demonstrated that the orbital flight did not induce significant MAMMALIAN TOXICOLOGICAL EVALUATION OF DIMP changes in the ultrastructure of blood vessels of the soleus and AND DCPD (PHASE 3 - IMPA) Final Report. Dec. 1976 - gastrocnemius muscles but caused atrophy of muscle fibers and Apr. 1980 reduction of the number of functioning capillaries. Readaptation Francis J. Mecler May 1981 277 p of the soleus vascular system to 1 g led to degradation of (Contract DAMD17-77-C-7003: DA Proj. 3E1-62720-A-835) permeability of capillary and venular walls and development of (AD-A107574) Avail: NTIS HC A13/MF A01 CSCL 06/20 edema of the perivascular connective tissue. This may be one IMPA (Isopropyl Methylphosphonic Acid) had oral LDSO's of the factors responsible for dystrophic changes in muscle of 7650 and 6070 mg/kg in male and female rats, respectively, fibers. Author and of 5620 and 6550 mg/kg in male and female mice. It was not irritant to rabbit eyes. It was mildly irritant to rabbit skin N82-17836# Joint Publications Research Service, Arlington. but produced no systemic toxicity at a dose of 2 mg/kg. IMPA Va. did not induce dermal sensitization in guinea pigs. No evidence BLOOD FIBRINOGEN AS RELATED TO IMMERSION IN of toxicity followed administration of IMPA in the drinking water WATER FOR SEVEN DAYS AND SHORT-TERM SPACE at levels up to 30OO ppm to rats for 90 days. IMPA was not FLIGHT mutagenic to five strains of Salmonella indicator organisms in A. N. Fomin In its USSR Rept.. Space Biol. and Aerospace the Ames assay both with and without rat liver activation. GRA Med.. V. 15. No. 5. Sep. - Oct. 1981 (JPRS-79346) 2 Nov. 1981 p 119-122 refs Transl. into-ENGLISH from Kosm. N82-17841# California Univ.. Irvine, Dayton. Ohio. Biol. Aviakosmich. Med. (USSR), v. 15. no. 5. Sep. - Oct. 1981 RESPIRATORY TOXICOLOGY. 1981 Annual Technical p 83-85 Report. Jun. 1980 - May 1981 Avail: NTIS HC A07/MF A01 Paul E. Newton Wright-Patterson AFB. Ohio AFAMRL Aug. A scrutiny of the literature dealing with hemocoagulation 1981 45 p refs under hypokinetic conditions revealed that blood fibrinogen was (Contract F33615-80-C-0512: AF Proj. 6302) studied exclusively in conjunction with other parameters character- (AD-A107672: AFAMRL-TR-81-81) Avail: NTIS izing the blood clotting system. Increase in fibrinogen concentration HC A03/MF A01 CSCL 06/20 in blood was demonstrated in individuals submitted to prolonged The Respiratory Toxicology research programs conducted at hypokinesia. patients restricted to bed rest and animals used in the Toxic Hazards Research Unit (THRU). Wright-Patterson Air experiments with hypokinesia. Blood tests were made on six Force Base by the University of California, Irvine are reviewed healthy men before, during, and after seven days of immersion in this annual report. Preliminary results are presented of in water as well as cosmonauts before and after seven and four studies concerning: (1) the effect of propylene glycol dinitrate day flights. The microtechnique for measuring the concentration on the cardiovascular system in the dog; (2) the evaluation of of fibrinogen in blood is based on the phenomenon of heat pulmonary clearance after exposure to 1.2 ppm of ozone, and denaturation of this protein at a temperature of 56 C. Results (3) the evaluation of small airway test sensitivity in enzyme indicate that the fibrinogen increased during the four to six days induced emphysema. Author (GRA) of the study. J.M.S. N82-17842# California Univ., Irvine. Dept. of Community N82-17837$ Joint Publications Research Service, Arlington, and Environmental Medicine. Va. COMPARATIVE BIOCHEMISTRY AND METABOLISM. METHOD OF ASSESSING INDIVIDUAL RESISTANCE OF PART 2: NAPHTHALENE LUNG TOXICITY Annual Report, HATS TO HYPOXIC HYPOXIA Jun. 1980 - May 1981 Yu. V. Farber, A. Yu. Grigoryev. and A. I. Yelfimov In its USSR Alan R. Buckpitt Wright-Patterson AFB, Ohio Aerospace Medical Rept.: Space Biol. and Aerospace Med.. V. 15. No. 5. Sep. - Research Labs. Oct. 1981 43 p refs Oct. 1981 (JPRS-79346) 2 Nov. 1981 p 123-125 refs (Contract F33615-80-C-0512; AF Proj. 6302) Transl. into ENGLISH from Kosm. Biol. Aviakosmich. Med. (USSR), (AD-A107673: AFAMRL-TR-81-84) Avail: NTIS v. 15. no. 5, Sep. - Oct. 1981 p 85-86 HC A03/MF A01 CSCL 06/20 Earlier studies have shown that intraperitoneal administration Avail: NTIS HC A07/MF A01 of naphthalene causes selective pulmonary bronchiolar necrosis The question of screening experimental animals according in mice and have suggested a role for reactive naphthalene to resistance to hypoxia is addressed in view of the need to metabolites in the tissue damage. These studies have been investigate individual distinctions with regard to resistance to extended to show that covalent binding of reactive naphthalene the body to various extreme factors, including a shortage of metabolites to tissue macromolecules in lung, liver and kidney oxygen. There are some methodological approaches to the study is dose-dependent. High levels of covalent binding occur only of this question. In particular, one determines coefficient K as after tissue glutathione levels are depleted substantially and only the ratio of rat survival time at an altitude of 12,000 m to at doses of 200 mg/kg and above. The 200 mg/kg dose is the restitution time. Experimental data on individual reactions to acute lowest dose at which lung lesions are observed. Piperonyl hypoxic hypoxia, which are obtained by determining the time of butoxide pretreatment decreases pulmonary damage and retention of the postural reflex with a static load are presented. covalent binding and partially blocks glutathione depletion by J.M.S. 400 mg/kg naphthalene. In comparison, SKF 525 A pretreatment decreased covalent binding levels to a much smaller extent and N82-17839# Institute de Pesquisas Espaciais, Sao Jose dos failed to alter glutathione depletion or pulmonary damage after Campos (Brazil). 400 mg/kg naphthalene. When compared to vehicle pretreated controls, phenobarbital or 3-methylcholanthrene pretreatment STUDY OF HOMING PIGEONS IN BRAZIL: SOME PRELIMINARY RESULTS produced no change in the severity of lung damage after doses R. Ranvaud Oct. 1981 16 p refs Presented at Intern. Symp. of naphthalene ranging from 50 to 400 mg/kg nor did these inducers alter covalent binding at doses of naphthalene of on Avian Navigation, Tirrenia, Italy, 14-18 Sep. 1981 (INPE-2248-PRE/032) Avail: NTIS HC A02/MF A01 200 mg/kg or less. Pretreatment of mice with p-xylene Observations of vanishing bearings are described. The ability preferentially inactivated pulmonary cytochrome p450 and of pigeons to home quite well under some rather unfavorable blocked naphthalene induced lung damage but failed to selectively conditions, namely with the Sun not too far from the zenith decrease covalent binding of reactive metabolites in the lung. and under total overcast in relatively weakly inclined magnetic Current studies are continuing to examine the role of cytochrome P450 dependent metabolic activation of naphthalene in the lung fields, as well as in cases where the inclination of the magnetic field actually reverses during the flight home is discussed. in the bronchiolar damage. Author (GRA) Homing in regions where the apparent diurnal motion of the Sun's azimuth reverses during the year, the midday Sun being N82-17843# Messerschmitt-Boelkow-Blohm G.m.b.H., Otto- to the north in June and to the south in December, is reported. brunn (West Germany). Abt. Angewandte Physik. Homing right across the so called south atlantic anomaly, at BIOPHYSICAL FUNDAMENTALS AND INSTRUMENTATION

133 N82-17844

FOR THE ENDOVESICAL Nd:YAG LASER APPLICATION p 11-16 refs Transl. into ENGLISH from Biol. Nauki (USSR), T. Halldorsson 5 Jun. 1981 25 p refs In GERMAN: ENGLISH no. 5. May 1981 p 24-28 summary Avail: Issuing Activity (MBB-UA-581-81-0) Avail: NTIS HC A02/MF A01 The effect of electromagnetic waves in the millimeter band The laser irradiation power needed (or tumor therapy was on the synthesis and activity of pencillinase produced by strains investigated. From considerations of the absorptivity of cellwater of Staphylococcus aureus and Escherichia coli is examined. and blood as well as the multiple scattering of the radiation Experiments demonstrated that wave lengths of 6,478 and and heat conduction in tissue, a theoretical model was developed 6.468 mm inhibit the induction of the enzyme by St. aureus. which enabled an accurate calculation of the temperature However, this type of radiation does not affect the activity of distribution up to the denaturation point as well as the percentage the exoenzyme released from the St. aureus strain, and also of the radiation power lost through backward and forward does not affect the constitutive synthesis of the penicillinase by scattering of light. The theoretical calculations were experimentally E. coli. The relationship of effect of the duration of irradiation, verified in animal experiments and measurements on specimens bacterial population, and the strength of current density is of human bladder tissue performed with a thermocamera. elucidated. Author According to the requirements of endoscopic laser therapy, a medical Nd:YAG laser system was developed. For the beam N82-17849# Joint Publications Research Service. Arlington. transport into the urinary bladder, flexible light pipes made from thin quartz fibers were used. A.R.H. Va. EFFECTS ON BIOLOGICAL SYSTEMS OF ELECTROMAG- NETIC OSCILLATIONS IN MILLIMETER RANGE OF N82-17844$ Joint Publications Research Service, Arlington, WAVELENGTHS Va. N. D. Devyatkov, 0. V. Betskiy, E. A. Gelvich. M. B. Golant. A. USSR REPORT: LIFE SCIENCES EFFECTS OF NONIONIZ- M. Makhov. T. B. Rebrova. L. A. Sevastyanova. and A. Z. ING ELECTROMAGNETIC RADIATION. NO. 4 Smolyanskaya In its USSR Rept.: Life Sci. Effect on Nonionizing 4 Jan. 1982 62 p refs Transl. into ENGLISH of various Electromagnetic Radiation. No. 4 (JPRS-79780) 4 Jan. 1982 Russian articles p 27-36 refs Transl. into ENGLISH from Radiobiol. (USSR), (JPRS-79780) Copyright. Avail: Issuing Activity v. 21. no. 2, Mar. - Apr. 1981 p 163-171 The effects of nonionizing electromagnetic radiation on Avail: Issuing Activity organisms and tissues are discussed. The main patterns of the effects of millimeter radiation of nonthermal intensity on various biological objects are discussed N82-17845$ Joint Publications Research Service, Arlington. on the molecular, cellular levels, as well as on the.level of Va. complex living organisms. The main objects of the studies were EFFECT OF COMMERCIAL FREQUENCY ELECTROMAG- hemoglobin and erythrocytes and human blood, E. coli. Staphylo- NETIC FIELD ON ANDROGEN FUNCTION OF RAT TESTS coccus aureus. Aspergilla mold, mice and rats. Author A. G. Reznikov and L. V. Tarasenko In its USSR Rept.: Life Sci. Effect on Nonionizing Electromagnetic Radiation, No. 4 N82-1785O# Joint Publications Research Service, Arlington, (JPRS-79780) 4 Jan. 1982 p 1-5 refs Transl. into ENGLISH Va. from Fiz. Zh. (USSR), v. 27. no. 1, Jan. - Feb. 1981 p 121-124 CURRENT PROBLEMS OF RADIOBIOLOGY OF ELECTRO- Avail: Issuing Activity MAGNETIC RADIATION OF RADIO-FREQUENCY RANGE The biological effects of commercial frequency electromagnetic fields (CFEMF) generated by high voltage electric power lines I. G. Akoyev In its USSR Rept.: Life Sci. Effect on Nonionizing on the gonads of male rats were investigated. The effect of Electromagnetic Radiation. No. 4 (JPRS-79780) 4 Jan. 1982 CFEMF on the endocrine function of rat tests consists of an p 37-43 refs Transl. into ENGLISH from Radiobiol. (USSR), v. intensification of steroidogenetic processes and a corresponding 20. no. 1, Jan. - Feb. 1980 p 3-8 increase in the activity of the steroid delta(5)-3 beta-o1 Avail: Issuing Activity dehydrogenase. No appreciable changes in testosterone levels in On the basis of analysis of the current state of the radiobiology peripheral blood plasma were observed following CFEMF of nonionizing radiation, the need for accelerated development irradiation for a period of four months. J.D.H. of basic research on the biological action of these radiations, especially in the radio-frequency range, is substantiated. An N82-17846# Joint Publications Research Service, Arlington, objective is set for accumulation of experimental data on questions Va. of reversibility and cumulative effects, selectivity, specificity and FEATURES OF METABOLIC DISTURBANCES IN RAT additivity. direct and indirect action, sensitivity, adaptation and MYOCARDIUM UNDER EFFECT OF ALTERNATING stability in regard to radiation, species differences, and possible MAGNETIC FIELDS OF DIFFERENT PARAMETERS mechanisms of operation of radiation. Author F. A. Kolodub. 0. N. Chemysheva. and G. I. Yevtushenko In its USSR Rept.: Life Sci Effect on Nonionizing Electromagnetic N82-17851# Joint Publications Research Service. Arlington. Radiation. No. 4 (JPRS-79780) 4 Jan. 1982 p 6-10 refs Va. Transl. into ENGLISH from Kardiologiya (USSR), v. 21, no. 4. PARTICULAR FEATURES OF CONDITIONED ELECTRODE- Apr. 1981 p 82-85 FENSIVE REFLEX IN WHITE RATS ON BACKGROUND OF Avail: Issuing Activity CONSTANT MAGNETIC FIELD The effect of alternating magnetic fields of various voltages I. V. Shust. S. I. Galantyuk, and Yu. V. Cheretyanko In its and exposures on the metabolism of carbohydrates, macroergic USSR Rept.: Life Sci. Effect on Nonionizing Electromagnetic phosphates, and low molecular nitrogen compounds in the rat Radiation. No. 4 (JPRS-79780) 4 Jan. 1982 p 44-50 refs heart was investigated. The direction and degree of metabolic Transl. into ENGLISH from Fiz. Zh. (USSR), v. 26. no. 2. Mar. - disturbances in the myocardium after exposure to industrial Apr. 1980 p 264-268 frequency alternating magnetic fields depend on the voltage of Avail: Issuing Activity the field and the length of exposure. An alternating magnetic The formation of a conditioned electrodefensive reflex in white field with a voltage of 32 kA/m delays oxidation and phosphoryla- rats exposed to a 1.000 Oe constant magnetic field was tion processes without affecting their coupling, and the proportion investigated. The influence of the vitamin preparation galascorbin of oxidized carbohydrates increases as compared with fatty acids. on the formation of the reflex was also studied. The tenacity of The conversion of carbohydrates and of nitrogen substances are the conditioned reflex was reduced by exposure to the CMF. stimulated by an alternating magnetic field with a voltage of with a greater reduction observed in the initial phase of its 7.5 kA/m. J.D.H. development. Changes in conditioned reflex activity were observed during exposure and during the aftereffect period. The threshold N82-17847# Joint Publications Research Service, Arlington, of the avoidance reaction initially increased, then decreased, with Va. normalization of the indicator observed until the end of the INFLUENCE OF ELECTROMAGNETIC WAVES IN MILLIME- experiment. Administration of galascorbin promoted tenacious TER BAND ON INDUCTOPROTEIN SYNTHESIS OF development of the conditioned reflex, which remained more PENICILUNASE BY STAPHYLOCOCCUS AUREUS pronounced in the CMF aftereffect period. J.D.H. A. Z. Smolyanskaya, A. M. Makhov, E. A. Gelvich. and M. B. Golant In its USSR Rept.: Life Sci. Effect on Nonionizing N82-17852# Joint Publications Research Service. Arlington, Electromagnetic Radiation. No. 4 (JPRS-79780) 4 Jan. 1982 Va.

134 N82-17859

MORTALITY IN ACUTE MYOCARDIAL INFARCTION AS (presumably through the lipid) portion of urea equilibrium exchange FUNCTION OF GEOMAGNETIC FIELD ACTIVITY IN was .0000258 cm/s which is 3.2 percent of the maximal rate. YEREVAN Dissert. Abstr. N. N. Karazyan and L. A. Akhverdyan In its USSR Rept.: Life Sci. Effect on Nonionizing Electromagnetic Radiation. No. 4 N82-178S6 Columbia Univ.. New York. (JPRS-79780) 4 Jan. 1982 p 51-55 Transl. into ENGLISH TEMPORAL INTEGRATION OF ACOUSTIC POWER FOR from Dokl. Akad. Nauk Arm. SSR (USSR), v. 22, no. 3. 1981 INTERRUPTED STIMULI AT SUPRATHRESHOLD LEVELS p 188-191 Ph.D. Thesis Avail: Issuing Activity Joyce Rodriguez-Arrufat 1981 132 p The medical history of patients who died from acute Avail: Univ. Microfilms Order No. 8125375 myocardial infarction in the city of Yerevan. Armenian SSR. during Threshold and suprathreshold temporal integration data 1974-1978 was analyzed and compared with records of employing experimental variables were investigated. Data were geomagnetic field activity. The basic causes of death from collected to experimental conditions: three stimulus types, nine complications of myocardial infarction were also evaluated. A signal durations and four presentation levels including threshold. direct connection was observed between the mortality rate and Subjects were three normal hearing listener who participated in increased magnetic activity, with men exhibiting a greater 20 practice sessions and 12 test sessions of 20 minutes each. sensitivity to high geomagnetic field activity than women. J.D.H. Mean threshold and point of subjective equality (PSE) values were calculated for each subject and each experimental N82-17863$ Joint Publications Research Service. Arlington, condition. It is indicated that the constants of the function are Va. a product of the interaction between stimulus type and intensity EFFECT OF HYPOGEOMAGNETIC FIELD ON ACTIVITY OF as incorporated in a two part linear regression model. It is SOME CEREBRAL ENZYMES suggested that critical duration decreases with intensity and is A. V. Shakula and G. M. Chernyakov In its USSR Rept.: Life essentially independent of stimulus type at 50 db and 80 dB Sci. Effect on Nonionizing Electromagnetic Radiation, No. 4 SPL. The slope of the function varies as a function of intensity (JPRS-79780) 4 Jan. 1982 p 56-59 refs Transl. into and stimulus type, being largest for 1000 Hz and smallest for ENGLISH from Gig. Sanit. (USSR), no. 9. Sep. 1981 p 11-13 white noise. These findings are discussed in terms of Zwislocki's Avail: Issuing Activity exponential theory of loudness summation. Dissert. Abstr. The activity of key brain enzymes of rabbits whose embryonic and early postnatal development occurred during exposure to a N82-17857 Ohio Univ.. Athens. hypogeomagnetic field was investigated. The activity of succinate QUANTIFICATION OF PSYCHOACOUSTIC TUNING CURVE denydrogenase (SDH), glucose-6-phosphate dehydrogenase SHARPNESS: AN ANALYSIS OF FREQUENCY RESOLU- (G-6-PDH), tetrazolium oxyreductanse (NAD-H), and hexokinase TION IN CHILDREN AND ADULTS Ph.D. Thesis (HK) as determined. Histological examination of neuronal bodies Neal Alan Sloane 1981 120 p of the cortex, of astroglia and oligodendroglia revealed very high Avail: Univ. Microfilms Order No. 8126067 G-6-PDH and NAD-H activity, moderate SDH activity, and mild Probe tone frequencies were pulsed with a rise/fall time of HK activity. A hypogeomagnetic field was found to be a 50 msec., duration of 400 msec., and were delivered at 10 dB biologically active factor having an adverse effect on the enzymes SL using a simultaneous masking paradigm. Masked threshold regulating energy metabolism. J.D.H. was determined using a modified Hughson-Westlake technique. After the first set of tuning curves was obtained, each subject N82-17854 Washington Univ., St. Louis. Mo. returned in 24 hours to replicate the test. Results, show that MUSCLE. MOTOR CORTEX, CEREBELLAR NUCLEAR. AND the main effect for age is nonsignificant, the main effect for SPINDLE AFFERENT DURING SLOW HOLD-RAMP-HOLD sessions also is nonsignificant, the main effect for frequency is POSITION-TRACKING MOVEMENTS OF THE MONKEY'S significant, and all possible interactions are nonsignificant. A Tukey WRIST Ph.D. Thesis Test, calculated for the main effect of frequency, established Marc Hudson Schieber 1982 469 p that all three tuning curves differ significantly from one another Avail: Univ. Microfilms Order No. 8122756 in sharpness, it is concluded that within the age range under Two Rhesus monkeys were trained to perform flexion and study, age does not influence tuning curve sharpness, d sub extension wrist movements guided by a tracking display. The 1 oct. values do not change significantly across experimental monkey used a wrist position control to operate a cursor with sessions, and tuning curves increase significantly in sharpness which he pursued a visual target. The target, and therefore the across probe tone frequencies of 500, 1000. and 2000 Hz. monkey's wrist, moved in slow hold-ramp-hold (HRH) trajectories. Dissert. Abstr. By changing parameters of the target's trajectory, changes were produced in the parameters of the monkey's wrist movement. N82 17858 Florida State Univ., Tallahassee. The second monkey was trained additionally to perform self-spaced A STUDY OF THE ACOUSTIC REFLEX AS ELICITED BY alternating wrist movements and to receive occasional pulses of SELECTED ENVIRONMENTAL NOISE STIMULI torque about the wrist. It is hypothesized that during slow HRH Ph.D. Thesis wrist movements, two parallel motor systems operated in relative Marshall Melvin Smith 1981 114 p dissociation. The first system included class I motor cortex neurons, Avail: Univ. Microfilms Order No. 8125790 alpha motoneurons, and extrafusal muscle. The second system The acoustic reflex thresholds (ARTs) for the environmental included class II motor cortex neurons, nearly all related noise ranged from 78.83 through 81.78 db SPL. The ARTs for dentate and interposed neurons, gamma motoneurons, and spindle the white noise, and the pure-tone were 81.38 and 95.19 dB afferents. This system could have provided for the continuous SPL, respectively. For all practical purposes (19%) the ARTs for acquisition of dynamically sensitive spindle afferent feedback the environmental noises lie within + or - 5 db of the ART for constantly maintained in the face of widely varying peripheral the white noise. The latency at threshold for the environmental conditions. Dissert. Abstr. noises ranged from 452.5 through 552.50 msec. Similarly, the latencies were 402.5 and 487.5 msec for the white noise and N82-17855 Minnesota Univ.. Minneapolis. the pure-tone, respectively. The latency at dB SL sub R (20 dB FACILITATED DIFFUSION OF SMALL NON-ELECTROLYTES above the threshold) for the environmental noises ranged from IN THE HUMAN RED BLOOD CELL 152 through 180 msec. There was a decrease in latency at Robert Ray Mayrand 1981 136 p 20 dB SL sub R compared to that at threshold across all the Avail: Univ. Microfilms Order No. 8125991 stimuli. The contraction rate at 20 dB SL sub R for all stimuli The design of a new simple continuous flow system for the ranged from .0009 through .0011 cc/msec. The contraction analysis of rates of permeation of small non-electrolytes across magnitude at 20 dB SL sub R for all the environmental noises human red cell membranes is described. With this system it and the white noise ranged from .669 through .816 cc. was demonstrated that ethylene glycol equilibrium exchange is Dissert. Abstr. saturable, KM = 175 mM, and inhibitable. glycerol K1 = 1200 mM. Ethylene glycol yielded a permeability coefficient of N82-17859 North Carolina Univ. at Chapel Hill. P sub s = .000336 cm/s. Urea equilibrium exchange was also STUDIES ON STRUCTURE AND FUNCTION RELATIONSHIP examined with the continuous flow system. Saturation was again IN FIBHINOGEN Ph.D. Thesis observed, KM = 218 mM. The maximal rate of urea exchange Nadia Aldyth Carrell 1981 160 p was P sub s = .000808 cm/s. The estimated non-inhibitable Avail: Univ. Microfilms Order No. 8125561

135 N82-17860

The literature concerning the chemical properties of fibrinogen MARINES OPERATING IN A DESERT ENVIRONMENT and the mechanisms of fibrinogen function was reviewed. The Paul 0. Davis, Arthur V. Curtis, Jr., and Steven A. Bixby Nov. experimental work was aided by the availability of two patients 1981 62 p refs with congenital molecular variants of fibrinogen and one patient (Contract N00014-80-C-0473) with an inhibitor to fibrin polymerization. The fibrinogen level in (AD-A107866: TR-7) Avail: NTIS HC A04/MF A01 CSCL the first patient was found to be about one third of the normal 15/7 level by both coagulation and immunologic methods. The second Nine representatives of the Institute of Human Performance patient had a low plasma level of clot able protein with normal were integrated into a marine battalion during a CAX (combined antigen concentration, high amounts of fibrinogen related material arms exercise) for the purpose of gathering descriptive and in serum, and prolonged thrombin and reptilase clotting times. objective information regarding the nature and types of physical The third patient developed an inhibitor which markedly prolonged performance tasks encountered by marine infantrymen (MOS the thrombin and reptilase times of both patient and normal 0311) during desert combat. Through the use of minicassette plasmas. A procedure was developed to direct chemical recorders, scales, cameras and other data collection equipment, modifications selectively at lysine residues which function in scenarios were described which typify the critical, frequent and polymerization. An assay to measure the binding of fibrinogen strenuous types of tasks indigenous to marines in this environment. to fixed washed platelets was developed. Dissert. Abstr. Distances covered on foot, loads carried, rates of travel and grades encountered are detailed and described as well as other environmental overlays which impact on troop performance. It N82 17860 Florida Univ.. Gainesville. was determined that for the most part, a mechanized, motorized FORWARD MASKING OF AUDITORY NERVE (N SUB 1) combat scenario does not require high levels of physical ability: AND BRAINSTEM RESPONSES (WAVE V) IN HUMANS however, fire team rushes represent a critical scenario, with Ph.D. Thesis high levels of aerobic and anaerobic power, particularly when Steven John Kramer 1981 186 p performed in ambient temperatures of 100-107 F. A taxonomy Avail: Univ. Microfilms Order No. 8127440 of physical tasks from this environment will be added to physical The influence of a response to one sound (probe) another performance data from other Marine Corps theaters of operations sound (masker) when the two sounds occur simultaneously or for the purpose of developing a complete job analysis of in a temporal relation was demonstrated. The effects of forward activities involving strength and endurance factors. Author (GRA) masking on wave-V of the ABR along with N responses recorded simultaneously (on a separate channel) from the ear canal were N82-17864# California Univ., Irvine. Dept. of Community investigated. Postmasking recovery functions were measured for different masker durations, masker levels, and masker low and Environmental Medicine. frequency cutoffs (high-pass masking). The effects on wave-V CYTOLOGIC AND BIOCHEMICAL GENETIC EFFECTS OF were different than on N1. The primary effects of forward masking CHEMICAL CARCINOGENS Annual Report. 1 Jul. 1980 - 30 Jun. 1981 on the probe responses were decreases in N1 amplitude and Ronald E. Rasmussen Wright-Patterson AFB, Ohio Aerospace increases in wave-V latency. Characteristic changes in the recovery functions for variations on masker parameters were found. It is Medical Research Lab. Oct. 1981 43 p refs suggested that the relation between wave-V latency and N1 (Contract F33615-80-C-0512: AF Proj. 6302) (AD-A107615: AFAMRL-TR-81-82) Avail: NTIS amplitude, along with other characteristics of underlying mechan- HC A03/MF A01 CSCL 06/20 isms include a recording of the neutral input (N1) within the brainstem pathways generating the wave-V potential. The first project is concerned with the relationship between initiation of cancer by chemicals and the damage and repair of Dissert. Abstr. DNA in cells and tissues susceptible to the carcinogenic action of the chemicals. The working hypothesis is that interaction of N82-17861 Ohio Univ.. Athens. the carcinogen with cellular DNA is a necessary step in HUMAN AUDITORY BRAINSTEM ELECTRIC RESPONSES carcinogenesis and that this interaction may cause DNA damage TO BINAURAL AND MONAURAL STIMULI Ph.D. Thesis which is then followed by DNA repair synthesis. The second Paul Alfred Lobaugh 1981 149 p project was conducted with the cooperation of the staff of the Avail: Univ. Microfilms Order No. 8126058 Toxic Hazards Research Unit at AMRL. WPAFB. Rats and hamsters The auditory brainstem electric response (ABER) is recorded were exposed by inhalation to hydrazine at 7 SO ppm for one from electrodes attached to the scalp of humans and consists hour. Groups of animals which had been exposed only once or of a series of sub-microvolt peaks which occur in the 10 ms which had been exposed 10 times were shipped to UC Irvine period following presentation of simple auditory stimuli such as for study. The factors studied were (1) DNA replication in the clicks. The ABER differences due to binaural and monaural lung; (2) DNA repair synthesis in the lung: (3) Cellular replication stimulation which are defined as binaural interaction are in the lung and nasal turbinat.es; and (4) Metabolism of a known investigated. It is also possible that binaural signal processing, lung carcinogen, 3H-Benzo(a)pyrene, by lung slices from the if reflected by the ABER. may occur in an asymmetric manner. treated animals. The third project was initiated during the current The effects of a stimulus variable, click polarity, and a subject year with the goal of developing an animal model in which variable, headsize. upon the ABER are studied. Click-evoked ABERs biochemical and cytogenetic factors could be studied during the were acquired from 44 normally hearing adolescent and adult process of tumorigenesis. Range-finding studies are underway subjects. Responses to binaural and monaural stimulation were at the Toxic Hazards Research Unit (THRU) to establish the analyzed. It is concluded that polarity of the stimulus does not intratracheal dosage of 3-methylcholanthrene (MCA) necessary affect ABERs in response to 60 and 70 dB SL clicks. For 80 dB to produce a high yield of lung tumors in Fischer 344 rats SL stimulation, negative polarity clicks evoke shorter latency waves within 12 months. GRA than do positive polarity clicks. Dissert. Abstr. N82-17865# California Univ., Irvine. Dept. of Community and Environmental Medicine. N82-17862*# Narco Scientific. Houston. Tex. COMPARATIVE BIOCHEMISTRY AND METABOLISM. PORTABLE MEDICAL STATUS AND TREATMENT SYSTEM PART 1: CARCINOGENESIS Annual Report. Jun. 1980 • Final Report May 1981 Dec. 1981 25 p Robert C. Shank Wright-Patterson AFB. Ohio Aerospace Medical (Contract NAS9-15821) Research Lab. Oct. 1981 38 p refs (NASA-CR-167496) Avail: NTIS HC A02/MF A01 CSCL (Contract F33615-80-C-0512; AF Proj. 6302) 06E (AD-A107614; AFAMRL-TR-81-83-PM) Avail: NTIS A portable medical status and treatment system is discussed. HC A03/MF A01 CSCL 06/20 The vital signs monitor includes electrocardiogram, respiration, Oral administration of the inorganic hepatotoxin, hydrazine. temperature, blood pressure, alarm, and power subsystems, which to male Fischer 344 or Sprague Dawley rats results in the are described. A DC defibrillator module, a radio module, and endogenous methylation of liver DNA at the 7- and 06-positions their packaging are also described. These subsystems were of guanine. At doses below the LD50 (45. 60 or 75 mg evaluated and the results and recommendations are presented. hydrazine/kg body weight), methylation levels varied little and S.L. averaged about 500 micromol 7-methylguanine/mol guanine.and N82-17863# Institute of Human Performance, Fairfax. Va. 20 micromol 06-methylguanine/mol guanine. At 90 mg PHYSICAL PERFORMANCE TASKS REQUIRED OF U. 8. hydrazine/kg body weight (approximately the 7-day LD50) the

136 N82-17873 methylation levels were 869 micromol 7-methylguanine and local intestinal nerves may participate in producing this hyperemia. 58 micromol 06-methylguanine/mol guanine 24 hours after The venous outflow of isolated canine jejunal segments, the toxicant administration. A single dose of 3 mg hydrazine/kg arteriovenous oxygen difference, and the rate of oxygen body weight did not result in detectable levels of methylguanines consumption were measured before and after administration of in liver DNA: however, after three or four daily administrations a local anesthetic and several neurotransmitter antagonists. of hydrazine at this dose, liver damage was evident, and liver Intestinal nerves do not appear to play a role in the intestinal ONA contained 50-100 micromol 7-methylguanine/mol gua- hyperemia produced by luminal placement of nutrient solutions. nine, about the limit of analytical detection. Following a single On the basis of the magnitude of hyperemic and metabolic oral administration of 90 mg hydrazine/kg body weight, liver responses, the hyperemia produced by glucose appears to be DNA guanine rapidly became methylated. The time for half- metabolically mediated. The oleic acid induced hyperemia more maximum alkylation at 7-guanine was 30 minutes and at closely resembles that produced by vasodilator chemicals. The 06-guanine, 45 minutes. The rates of removal of these methylated hyperemia produced by food would likely involve a combination bases were consistent with published values from experiments of these mechanisms. Dissert. Abstr. using methylating carcinogens and with values obtained in this laboratory with the model compound, 1,2-dimethylhydrazine. N82-17870 Yale Univ.. New Haven. Conn. GRA REGULATION OF CALCIUM CURRENT AND CALCIUM ACTIVITY IN HEART CELLS Ph.D. Thesis N82-17866$ Environmental Protection Agency, Ann Arbor, Mich. Eduardo Marban 1981 152 p Inspection and Maintenance Staff. Avail: Univ. Microfilms Order No. 8125689 HEALTH EFFECTS OF CARBON MONOXIDE AND OZONE The regulation of calcium current in mammalian ventricular Jul. 1981 20 p refs Prepared in cooperation with Energy muscle and Purkinje fibers was studied by voltage clamp technique. and Environmental Analysis, Inc., Arlington, Va. The effects of changes in intracellular calcium on the size of (PB82-114265; EPA-AA-IMS-81-8) Avail: NTIS the slow inward calcium current (I sub si) were found to explain HC A02/MF A01 CSCL 06T the digitalis-induced increase in this current, as well as some The information known about the health effects of carbon properties of the inactivatidn of I sub si. The involvement of monoxide (CO) and ozone (03) is summarized. How that K+ as a charge carrier of the transient outward current is shown information is used by EPA to set National Ambient Air Quality Ca entry leads to inactivation. as previously suggested for Standards is discussed. The sources most likely to contribute to Paramecium, Aplysia neurons, and stick insect skeletal muscle. high levels of CO and O3 and how EPA control programs will Enhancement of I sub si is observed in association with the reduce emissions from these sources in the future are discussed. positive inotropic effect of digitalis. It is suggested that a rise in The health effects on humans and plants are discussed. Na sub I leads to increased I sub si possibly through a secondary Author (GRA) rise in Ca. Quiescent ventricular muscle, a mean free Ca2 + concentration of micro is found. During contractures, transients N82-17867 American Univ., Washington. D. C. rising up to 10 micro are reported. In studying the effects of A MODEL FOR ESSENTIAL HYPERTENSION: METABOLIC catecnolamines on free Ca2+ and force, it is evidenced that STUDIES Ph.D. Thesis epinephrine reduces myofibrillar Ca2+ sensitivity in hetfrt James Patterson Church 1981 101 p muscle. Dissert. AbStr. Avail: Univ. Microfilms Order No. 8126862 The extent to which blood pressures and tissue lipid levels N82-17871*# National Aeronautics and Space Administration. are manipulated by dietary control of low levels of essential Langley Research Center, Hampton, Va. fatty acids in rat strains used as models of hypertensive and AN EVALUATION OF HELICOPTER NOISE AND VIBRATION normotensive man were determined. Procedures included RIDE QUALITIES CRITERIA gravimetric total lipids, colonmetric cholesterol and phospholipids, C. E. Hammond. D. D. Hollenbaugh, S. A. Clevenson. and J. D. fluorimetric triglycerides and gas liquid chromatographic fatty Leatherwood Dec. 1981 14 p refs Presented at the Technol. acids. Samples were taken from plasma liver and kidney. Total for the Jet Smooth Ride. A Natl. Specialists' Meeting on Helicopter lipids were lower in plasma, liver, and kidney of the SHR than Vibration. Hartford. Conn., 2-4 Nov. 1981: sponsored by the the WKY. Liver triglyceride and kidney cholesterol and phospholipid American Helicopter Society Prepared in cooperation with Army (PL) were lower with liver PL higher in SHR than in WKY. Research and Technology Lab., Fort Eustis, Va. Total individual fatty acids in plasma and in neutral lipid and PL (NASA-TM-83251) Avail: NTIS HC A02/MF A01 CSCL fractions of liver and kidney exhibited several strain and diet 05H differences. A high metabolic rate in the SHR suggests defective Two methods of quantifying helicopter ride quality: absorbed transport of essential fatty acids from the liver. Dissert. Abstr. power for vibration only and the NASA ride comfort model for both noise and vibration are discussed. Noise and vibration N82-17868 California Univ., San Diego. measurements were obtained on five operational US Army CEREBRAL HEMISPHERIC ACTIVITY AND AUTOMONIC helicopters. The data were converted to both absorbed power NERVOUS FUNCTION Ph.D. Thesis and DISC'S (discomfort units used in the NASA model) for Deborah Ann Werntz 1981 130 p specific helicopter flight conditions. Both models indicate Avail: Univ. Microfilms Order No. 8125444 considerable variation in ride quality between the five helicopters An otherwise unknown relationship between cerebral and between flight conditions within each helicopter. T.M. hemispheric activity, as exhibited by the EEC, and the autonomic nervous system as exhibited by the nasal cycle and its self-induced N82-17872*# Singer Co., Sunnyvale, Calif. alteration as regulated by forced uninostril respiration is VTOL/STOL VISUAL STUDY Final Report demonstrated. It is proposed that the correlation of the nasal Frank P. Lewandowski Jun. 1980 38 p cycle with alternating relative EEC amplitude asymmetry is (Contract NAS2-10222) indicative of and consistent with a single ultradian ocillator system. (NASA-CR-166292) Avail: NTIS HC A03/MF A01 CSCL It is also proposed that the nasal cycle is controlled via a central 051 mechanism, whereby the hypothalamus regulates the sympathet- The development of data bases and real time techniques to ic/parasympathetic balance and the vasomotor tone throughout improve the realism of sea state, bow and stern wake, and ship the body. The 'feedback' effect of nasal airflow on EEC asymmetry motion is addressed. This system was designed for use with is mediated through the olfactory system and its connecting the Vertical Motion Simulator to perform basic studies on pathways to the hypothalamus. The data demonstrate the VTOL/STOL aircraft. B.W. individual's ability to noninvasively and predictably after cortical activity and possibly other autonomic functions. Dissert. Abstr. N82-17873| Ounlap and Associates. Inc.. La Jolla, Calif. DEVELOPMENT OF THE AUTOMATED PERFORMANCE N82-17869 Michigan State Univ.. East Lansing. ASSESSMENT AND REMEDIAL TRAINING SYSTEM THE ROLE OF INTESTINAL NERVES IN THE NUTRIENT (APARTS): A LANDING SIGNAL OFFICER TRAINING AID INDUCED INTESTINAL HYPEREMIA Ph.D. Thesis Final Report. Sep. 1979 - Mar. 1981 Richard Arlan Nyhof 1981 124 p Steven T. Breidenbach and Clyde A. Brictson Orlando. Fla. Naval Avail: Univ. Microfilms Order No. 8126536 Training Equipment Center Jun. 1981 53 p refs The blood flow to the small intestine increases following a (Contract N61339-79-D-0105) meal, and this hyperemia appears to be localized to those portions (AD-A106224; NAVTRAEQUIPC-79-D-0105-1) Avail: NTIS of the intestine exposed to nutrients. Evidence indicates that HC A04/MF A01 CSCL 05/9

137 N82-17874

Development of the automated performance assessment and remedial training system (APARTS) is described. The APARTS is an automated training aid designed to assist the landing signal officer (LSO) in training pilots during the acquisition of carrier landing skills. The APABTS is based on general principles of learning and provides graphic displays of pilot landing technique problems for LSO evaluation and pilot feedback. The APARTS also integrates field carrier landing practice, conducted in the aircraft, with night carrier landing training (NCLT) instruction. Once landing problems are identified and feedback is provided to the pilot, remedial instruction is given in the NCLT. An improved APARTS conceptual model along with two computer programs designed to process, store and graphically display pilot performance data are described. Future APARTS developments are outlined for improved carrier landing effectiveness. GRA

N82-17874*# Purdue Univ., Lafayette, Ind. School of Aeronautics and Astronautics. TIME DOMAIN IDENTIFICATION OF AN OPTIMAL CONTROL PILOT MODEL WITH EMPHASIS ON THE OBJECTIVE FUNCTION David K. Schmidt 1982 22 p refs Presented at AFFTC/NASA Dryden/AIAA Workshop on Flight Testing to Identify Pilot Workload and Pilot Dynamics, Edwards, Calif., 19-21 Jan. 1981 (Grant NAG4-1) (NASA-CR-168487) Avail: NTIS HC A02/MF A01 CSCL 05H A method for the identification of the pilot's control compensation using time domain techniques is proposed. From this information we hope to infer a quadratic cost function, supported by the data, that represents a reasonable expression for the pilot's control objective in the task being performed, or an inferred piloting strategy. The objectives for this method are: (]) obtain a better understanding of the fundamental piloting techniques in complex tasks, such as landing approach; (2) the development of a metric measuurable in simulations and flight test that correlate with subjective pilot opinion: and (3) to further validate pilot models and pilot vehicle analysis methods. E.A.K.

N82-17875*# National Aeronautics and Space Administration. Goddard Space Flight Center, Greenbelt. Md. HUMAN-MACHINE INTERFACE ISSUES IN THE MULTI- SATELLITE OPERATIONS CONTROL CENTER 1 (MSOCC-1) Technical Memorandum, 1 Jun. - 7 Aug. 1981 Christine M. Mitchell (George Mason Univ.) Aug. 1981 68 p refs (NASA-TM-83826) Avail: NTIS HC A04/MF A01 CSCL 05H An analysis of the Multisatellite Operations Control Center facilities (MSOCC-1) is presented. The analysis focuses on the human machine interfaces and interactions present in the data operations control area, the computer support operations, and the mission operations rooms in both current facilities and the proposed automated MSOCC-1. An alternative approach to the design of the automated MSOCC-1, which highlights human factors and human machine interaction dimensions of the design process, is also presented. S.L.

N82-17876$ Federal Aviation Administration, Washington, D.C. DOT/FAA HUMAN FACTORS WORKSHOP ON AVIATION. TRANSCRIPT, VOL 1 Nov. 1980 112 p Workshop held at Cambridge, Mass., 24-25 Nov. 1980 2 Vol. (AD-A107802) Avail: NTIS HC A06/MF A01 CSCL 01/2 The opinions of airline pilots are considered in a presentation of aviation human factors safety issues. Human behavior is considered in the design, operation, and maintenance of aviation man machine systems. GRA

N82-17877# Federal Aviation Administration, Washington, D.C. DOT/FAA HUMAN FACTORS WORKSHOP ON AVIATION. TRANSCRIPT, VOLUME 2 25 Nov. 1980 219 p refs Workshop held at Cambridge. Mass.. 24-25 Nov. 1980 (AD-A107803) Avail: NTIS HC A10/MF A01 CSCL 01/2 Training issues and flight fatigue are considered in a presentation of aviation human factors safety issues. Human behavior is considered in the design, operation, and maintenance of aviation man machine systems. GRA

138 SUBJECT INDEX AEROSPACE MEDICINE AND BIOLOGYM Continuing Bibliography (Suppl. 232) MAY 1982

Typical Subject Index Listing

SUBJECT HEADING | Possible iopact of cosmochemistry on terrestrial biology - Historical introduction 482-21987 AL6AB Organic matter in meteorites and Precambrian rocks [—Laser induced fluoroescence from algae: Results - Clues about the origin and development of of a ship-borne field test living systems [NASA-TH-76626] N82-11758 482-21988 Problems in the rate of evolution in biological systems 482-21989 ACCEIBBAIIOH (PHYSICS) Acceleration measures and motion sickness incidence [4D-4107996] H82-16734 ACCE1BHAJI08 STBBSSES (PBISIOLOGX) The title is used to provide a description of the subject matter. When the Acceleration induced voltage variations in the title is insufficiently descriptive of the document content, a title extension electrocardiogram during exhaustive simulated is added, separated from the title by three hyphens. The NASA or AIAA aerial combat maneuvering accession number is included in each entry to assist the user in locating 482-21683 the abstract in the abstract section of this supplement. If applicable, a report Cathepsin activity of skeletal muscle and number is also included as an aid in identifying the document. myocardia myofibrils after exposure to weightlessness and accelerations H82-16714 Condition of meningeal nervous system during repeated exposure to transverse accelerations ABU.I1IBS H82-16730 Ability differences and cognitive napping skill ACCELBHATIOS TOIBBAJCB [AD-A106389] N82-16741 Regional distribution of cardiac output in ABIOGEIBSIS unanesthetized baboons during +Gz stress with Hew data on abiogenic synthesis of prebiological and without an anti-G suit compounds in volcanic processes 482-21681 482-20017 The effects of horizontal body casting on blood A theory of the origin of life volume, drug responsiveness, and +Gz tolerance 482-20023 in the rhesus monkey 4 neutral theory of biogenesis 482-21682 482-20024 Acceleration measures and motion sickness incidence Cooets and the origin of life - Bibliography [AD-A107996] N82-16734 482-20871 Combined effect of simulated weightlessness and Origin of life; Proceedings of the Third ISSOL accelerations on energy metabolism enzymes Meeting and sixth ICOL fleeting, Jerusalen, H82-17820 Israel. June 22-27, 1980 MXLIH&TIZA1TOB 482-20901 Lavs governing readaptation for seamen after a Abiotic organic synthesis in space low-latitude cruise 482-20910 482-20310 Far DV photolysis of methane-water gaseous ACIDS mixtures and the prebiotic synthesis of aldehydes Hamoalian toxicological evaluation of DIHP and 482-20913 DCPO (Phase 3 - Id PA) Chemical evolution and plate tectonics £4D-4107574] H82-17840 482-20918 ACOOSIIC FAIIGOB Photoassisted carbon dioxide reduction and Heuronal-glial alterations in the cerebral cortex fomation of tvoand three-carbon compounds of animals under the influence of white noise prebiological photosynthesis A82-21769 482-20920 ACOOSIIC fEtOCIlt Abiotic synthesis of phosphoric esters of Temporal integration of acoustic power for monosaccharides according to the 'cold model1 interrupted stimuli at suprathreshold levels 482-20923 H82-17856 Synthesis and degradation of amino acids by ACTIVATIOi BBBBGI contact glow discharge electrolysis, a possible The temperature dependence of the kinetics of route for prebiotic formation of bio-organic isometric myocardium relaxation compounds 482-19748 482-20924 ACTIVITY (BIOLOGY) Genesis of aaino acids in the primeval sea - The effect of motor activity on the development of Formation cf amino acids from sugars and ammonia cardiac arrhythmias in experimental emotional in a modified sea medium stress 482-20925 A82-21713 Porphyrin-like compounds genesis under simulated Activation of succinate dehydrogenation in rat abiotic conditions liver by noradrenalin, cAHP and acute cooling 482-20926 482-21734 Potentiometric titration behavior of polyaaino An investigation of the biological activity of acids prepared by thermal polycondeusation chalones separated from normal livers and from 482-20938 livers that are being regenerated Primitive transfer BH4 and origin of Darwinian 482-21742 system ACliriXI CICIBS (BIOL06I) 482-20959 Cerebral hemispheric activity and automonic nervous function H82-17868

1-1 4CTIAIIOI SUBJECT IBDBI

ACII.ATIOI Siaulation of soae of man's movements in different Quantua mechanical conformational analysis of gravity fields aminoacyladen;lates - Inplication in the origin 882-16712 of life Positions, movements and equilibrium of rats after 482-20941 flights ab.oard biosatellites Selective acylability of anino acids by H82-16713 nou-enzymic nodel reactions of biocheaical Cathepsin activity of skeletal muscle and transacylations myocardia oyofibrils after exposure to A82-20965 weightlessness and accelerations ADAPTATION 882-16714 Psychological problems in the mutual adaptation of Cytokinetic evaluation of erythropoiesis during man and machine in control systems Russian long-term orbital flights book H82-16715 482-19000 Norepinephrine and enzymes of synthesis and Contractile dysfunction of vascular vail smooth degradation thereof in the rat hypothalamus muscle under emotional nociceptive stress following flight aboard the Cosmos-936 482-20322 biosatellite Changes in the structure and cellular composition H82-16716 of the inguinal lymph nodes of white rats Hygienic principles of ongoing monitoring of subjected to static and dynamic stresses quality of recycled vater during space flights 482-21761 H82-16717 Poststimulatory auditor; adaptation in humans Toxicological and hygienic aspects of improving according to computer audiometry additional purification of vater reclaimed from 482-21791 urine ADAPTIVE COHTBOL 882-16718 Psychological problems in the mutual adaptation of Possible use of house fly larvae for utilization man and machine in control systems Bnssian of organic vaste in biological life-support book systems 482-19000 B82-16719 ADB1I1ES Distinctions of regeneration of confined HCH oligomerization - Isolation and preliminary atmosphere by means of photosynthesis of characterization of a new precursor of adenine unicellular algae 482-20930 1182-16720 ADIPOSE TISSUES Phenomena of fluctuation of human reaction to 6lycogee and nonspecific adaptation to cold antiorthostatic position 482-19494 882-16721 ADBEIA1 G1AMD Besnlts of study of hemodynamics and phase Functional condition of the rat sympato-adrenal structure of the cardiac cycle during functional system during emotional and nociceptive stress test vith lover body negative pressure during 482-20335 140-day Salyut-6 station flight ADBBIAi BETABOLISH 882-16722 Stationary magnetic fields and reticular Succinate dehydrogenase and cytochrome oxidase influences on adrenergic and cholinergic systems activity in tissues of rats submitted to H82-16725 long-term hypokinesia Human adrenosyopathetic system during immersion in 882-16723 vater Lipid spectrum of the myocardium of vhite rats 1182-17819 exposed to hypoxic hypoxia ADSOBPIIOI 882-16724 Possible selective adsorption .of enactiomers by Stationary magnetic fields and reticular Na-montmorillonite influences on adrenergic and cholinergic systems 482-20916 882-16725 AEHOEBBOLISH Clinical distinctions of radiation sickness vith Air embolism - Possible rcle of surfactant on exposure of different parts of the human body to recompression radiation 482-21931 H82-16726 ABB01AUTICAL E16IHEEBIB6 Electrode unit for testing human H reflex DOT/F4A Human factors iorkshop on Aviation. 882-16728 Transcript, vol 1 Comparative antihypoxic efficacy of pressure [4D-4107802] 882-17876 chamber conditioning and fasting of man DOT/FAA Human Factors lockshop on Aviation. 882-16729 Transcript, volume 2 Condition of meniugeal nervous system during IAD-4107803] 882-17877 repeated exposure to transverse accelerations AEROSPACE ElVIEOHaEiSS 882-16730 * Could life have evolved in cometary nuclei 4FFEBEHI BEB70DS SISTEHS 482-20025 Muscle, motor cortex, cerebellar nuclear, and Survival in space spacesuit development spindle afferent during slov hold-ramp-hold 482-20257 position-tracking movements of the monkey's vrist Bat amino acid composition after flight aboard 882-17854 Cosmos-1129 biosatellite AGE FACIOB 882-17831 Phasic energy analysis of rheoencephalograms in 4EBOSP4CE HBDICIHB the detection of the decompensation of cerebral Investigation of the otclithic membrane of the heaodyhamics utricle of the guinea pig 482-21754 182-20301 The effect of physical training on the lipid and Special and clinical physiology of hypoxic states lipoprotein metabolism in people of various ages 482-20317 482-21757 The prevalence of visual deficiencies among 1979 Age morphofunctional characteristics of chromaffin general aviation accident airmen tissue in the celiac nodes, both in the norm and 482-21688 vith hypokinesia Honesterified fatty acid metabolism daring 482-21766 exercise in humans LDH isoenzyme spectrum in intact and denervated 482-21809 skeletal muscles of rats of various age during OSSB report: Space biology and aerospace cold adaptation medicine, volume 15, no. 6, November - December 482-21798 1981 4ge related distinctions of cosmonauts regional [JPBS-79849] 882-16704 heaodynamics Question of redistribution of blood in orthostatic 882-17829 position H82-16705

1-2 SOBJECT I8DBX iHIHO ACIDS

AGHICULTOBB ALGAE Variation in plant response to ozone: A . Distinctions of regeneration of confined conceptual model of physiological events atmosphere by means of photosynthesis of [DE81-029692] 882-16701 unicellular algae AIB FLOi 882-16720 A computational model for expiratory flow ALKALOSIS A82-21929 Variability of oxygen affinity of blood - Hunan AIB EOLLDTIOS subjects native to high altntude Variation in plant response to ozone: A A82-19493 conceptual model of physiological events ALTITDDE ACCLIBAIIZATIOI [DE81-029692] 882-16701 Alterations in responses to drugs of atria from Health effects of careen monoxide and ozone white rats acclimated to hypobaric hypoxia [PB82-114265] H82-17866 A82-19497 AIB QUALITY Functional condition and work capacity under Health effects of carbon aonoxide and ozone mountain conditions [PB82-114265] 882-17866 A82-20313 AIB TRAFFIC COBIEOL The role of natriuresis in the prophylactic effect Computer simulation as a visual aid in a video of adaptation to hypoxia in the case of coarse for ATC system performance hereditary hypertension A82-19248 A82-21712 AIB TBAISPOBTATIOB Adaptation to high-altitude hypoxia at different Physical and physiological features of long-range ambient temperatures /before and during flight and its inpact on patients adaptation/ A82-19012 A82-21715 AIRCRAFT ACCIOB11 IBVBSTIGATIOI Lysosomes under conditions of stress Tie prevalence of visual deficiencies among 1979 A82-21770 general aviation accident airmen Mechanisms of adaptation to ergothermic hypoxemia A82-21688 in athletes specializing in different sports AIRCRAFT IHDDSTBI A82-21820 DOT/FAA Human Factors iorkshop on Aviation. Comparative antihypoxic efficacy of pressure Transcript, volaae 2 chamber conditioning and fasting of man [AD-A107803] 882-17877 882-16729 AIRCRAFT LAIDIIIG ALTITUDE SIHOLAIIOB Development of the intonated Performance Comparative antihypoxic efficacy of pressure Assessment and Bemedial Training System chamber conditioning and fasting of man (APABTS): A landing signal officer training aid 882-16729 [AD-A106224] 882-17873 ALTITUDE TOLEBAHCE Time domain identification of an optimal control Method of assessing individual resistance of rats pilot model with emphasis on the objective to hypoxic hypoxia function 882-17837 [BASA-CB-168487] 882-17874 ALVEOLAI AIB AIBCBAFI IOISB Breath-by-breath measurement of true alveolar gas An evaluation of helicopter noise and vibration exchange ride qualities criteria A82-19498 [HASA-TH-83251] 1182-17871 The significance of airflow resistance to changes AIBCBAFI PILOTS in responses to increasing hypercapnia The prevalence of visual deficiencies among 1979 A82-20327 general aviation accident airmen Rate of uptake of carbon monoxide at different A82-21688 inspired concentrations in humans iays and means of maintaining heat balance in A82-21930 pilots and cosmonauts AHBIBBT TEMPBBATOHB 882-16706 Adaptation to high-altitude hypoxia at different In-flight diets and quantitative adequacy thereof ambient temperatures /before and during to pilot expenditure adaptation/ 882-17813 A82-21715 Cardiac output and cardiac cycle phase structure The effects of elevated environmental temperature of pilots during flights combined with radiation on the organism .882-17821 A82-21752 Time domain identification of an optimal control Effects of temperature on the duration of arousal pilot model nith emphasis on the objective episodes daring hibernation function A82-21934 [BASA-CB-168487] 882-17874 AHBOLABCES DOT/FAA Human Factors iorkshop on Aviation. Physical and physiological features of long-range Transcript, vol 1 flight and its impact on patients [AD-A107802] 882-17876 A82-19012 AIBLIIB OPBBATIOBS AHIBBS Flight simulation in the current Australian Brain monoamine oxidase activity during cold airline scene adaptation and under the combined effects of A82-20534 cold and hyperbaric oxygenation Effects o£ long-term exposure to Ipv levels of A82-19746 ozone - A review The effect of Ion temperature on the activity and A82-21676 substrate specificity of monoamine oxidases in ALAIIIB rat brain mitochondria The influence of some triterpenic glycosides on A82-21735 C-14-alanine inclusion into the bone-narrow AHIBO ACIDS cells of rats Amino acids derivatives synthesis from nitrogen, A82-20306 carbon and water by electric discharges Asymmetrical radical formation in beta-irradiated 482-20018 D- and L-alanines Search for effect of longitudinally polarized A82-20949 protons on optically active amino acids The effects of daily blood sampling on creatine A82-20021 phosphokinase, aspartate aminotransferase and Origin of translation - The hypothesis of alanine aminotransferase activities in the blood permanently attached adaptors proposed serum of the monkey prebiotic amino acid synthesis A82-21811 A82-20022 ALDEHIDBS A theory of the origin of life Far DV photolysis of methane-water gaseous A82-20023 mixtures and the prebiotic synthesis of aldehydes A82-20913

1-3 AHHOIIA SUBJECT IBDSX

The Strecker synthesis in the primitive ocean 4BESTBESI4 chenical evolution Computer-aided analysis of the effect of the £82-20919 initial narcosis on the central hemodynamics Synthesis and degradation of anino acids by 482-21797 contact glow discharge electrolysis, a possible 4BES1HBTICS route for prebiotic fornation of bio-organic 4 comparative evaluation of the hemodynamic compounds effects of large doses of morphine, dipidolor, 482-20924 pentazocine. and phentanyl Genesis of amino acids in the primeval sea - 482-21795 Fornation of amino acids from sugars and ammonia AHGIBA PEC10BJS in a modified sea medium Hicrocirculation, tolerance to physical strain, 482-20925 and certain homeostasis parameters in patients Factors influencing the rate of non-enzymatic with angina pectoris activation of carboxylic and amino acids by ATP 482-20324 182-20929 ABTABC3IC BEGIOBS Cyanamide mediated syntheses of leu, ala, and phe Organic analysis of. the Antarctic carbonaceous peptides under plausible primitive earth chondrites conditions 482-20908 482-20931 ABTIBODIES The polymerization products of The effects of successive ionizing radiation and alpha-aaincpropionitiile - The component heat on antibody formation separation using cation-exchange resin 482-21751 482-20934 AHXIDIOBBIICS Terrestrial evolution of polymerization of amino Effects of vasopressin administration on diuresis acids - Heat to 4TP of vater immersion in normal humans 482-20937 482-19491 Potentiometric titration behavior pf polyamino AiTIGBBS acids prepared by thermal polycondensation 4 study of tropomyosins in human muscular and 482-20938 nonmuscular organs On the polycondensation of amino acid adenylates 482-21806 on montmorillcnites ABTIOIIDABTS 482-20939 Elevation of hypoxia resistance with the use of Polymerization of serine guanylate in the presence gutimine of montmorillonite A82-20319 482-20940 AHT1SEPIICS Quantum mechanical conformational analysis of Comparative evaluation of antimicrobial activity aminoacyladenylates - Implication in the origin of some urine preservatives of life B82-17830 482-20941 ABOOSAl Environmental conditions for the formation of Effects of temperature on the duration of arousal marigranules and kinetic studies on the formation episodes during hibernation chemical evolution of amino acids in sea A82-21934 medium ABBHTXHBIA 482-20942 Investigation and evaluation of cardiac Resolution of underivatized amino acids by high arrhythmias in healthy young persons pressure liquid chromatography, using chiral 482-21710 elnants The effect of motor activity on the development of 482-20944 cardiac arrhythmias in experimental emotional Possible selective adsorption of enantiomers by stress Ba-montfflorillonite 482-21713 482-20946 ABTBBIBS Origin and evolution of the genetic code The role of extracellular O2 and C02 tensions in 482-20955 membrane mechanisms of cerebral arterial smooth Evolutionary processes of the genetic code muscle regulation 482-20957 482-19747 Summary of evidence for an anticodonic basis for Parameters of the interaction of bradykinin with the origin of the genetic code cardiovascular system receptors 482-20958 482-20332 Selective acylability of amino acids by The effect of blood pressure in the pulmonary non-enzymic model reactions of biochemical artery on gas exchange in functionally trahsacylations heterogeneous lungs 482-20965 482-21738 The multiple forms of tyrosine aninotransferase in ABTBBIOSCIEBOSIS rat liver cells and their role in cellular Phasic energy analysis of rheoencephalograms in homeostasis the detection of the decompensation of cerebral 482-21807 hemodynamics The dynamics and physiological importance of the A82-21754 activation of the ganma-anino-butyric acid ASCOBBIC ACID HBIABOLISH system in the brain and cardiac muscle under Vitamin C, B sub 1 and B sub 6 excretion in urine pain and emotional stress during 182-day antiorthostatic hypokinesia 482-21808 B82-17824 Temperature dependence of alanine and aspartate ASSBSSHEMS aminotransferase activities in rat brain during Development of the Automated Performance hypothermia of various durations and adrenalectomy Assessment and Bemedial Training System 482-21812 (4P4BTS): 4 landing signal officer training aid 4BBOII4 [AD-1106224] H82-17873 Photolysis of CH4-BH3 mixtures and PH3 as models ASTBOHADT TBAIHIBG for the photochemical transformations on the Staying sane in space primitive earth and Jupiter A82-19743 482-20914 ATAXIA Genesis of aaino acids in the primeval sea - Postnrography of ataxia induced by Coriolis- and Formation of amino acids from sugars and ammonia Purkinje-effects in a modified sea medium 482-21684 182-20925 ATHLETES ABALGESIA An electron microscope study of byperplasia in The effects of narcotic analgesics on animal fibers of the skeletal muscles of athletes sensitivity to hypoxia A82-21764 182-20316

1-4 SOBJBCI IBDBI B4CIBBI*

The dynamics of heart rate recovery following work Peculiarities of the middle ear structure in of various aerobic intensities rodents as an index of the frequency tuning of 482-21815 their auditory system Trial on the use of stabilography in the oedical 482-21714 supervision of boxers Auditory depth perception - Localization of A82-21817 nonnoving and moving sound sources Effect of the functional properties of the A82-21727 vestibular analyzer on the effectiveness of Cochlear analysis of sound intensity and some instruction in gymnastics mechanisms of auditory sensations 482-21819 A82-21792 Hechanisms of adaptation to ergothetnic hypoxemia Temporal integration of acoustic power for in athletes specializing in different sports interrupted stimuli at suprathreshold levels A82-21820 H82-17856 Stress and immunity in athletes Quantification of psychoacoustic tuning curve A82-21821 sharpness: An analysis of frequency resolution Badiometric determination of potassium content in in children and adults athletes H82-17857 482-21822 Forward masking of auditory nerve (H sub 1) and AIHOSPHBBIC CHBBISTBY brainstem responses (Rave V) in humans Comets and the photochemistry of the paleoatmosphere H82-17860 482-20866 Human auditory brainstem electric responses to Formation of prebiotic precursors from model binaural and monaural stimuli reducing atmospheres Bcle of hydrogen escape H82-17861 482-20911 AODITOBI SIGHALS Photolysis of CH4-HH3 mixtures and PH3 as models Forward masking of auditory nerve (H sub 1) and for the photochemical transformations on the brainstem responses (Have V) in humans prinitive earth and Jupiter H82-17860 482-20914 AODITOBI SXXBOLI Possible role of phosphine in chemical evolution vestibular responses of neurons in the feline 482-20915 anterior suprasylvian gyrns and their ATflOSPHEBIC HODBIS interaction with responses to acoustic and Abiotic synthesis of phosphoric esters of facial stimuli monosaccharides according to the 'cold model' 482-20309 482-20923 ElectrOencephalographic correlates of the 4TBOSPHBEIC TBHPBBA10BE differentiation between verbal stimuli during Certain features of cerebral hemodynamics in doing natural night sleep in humans mental vork at different air temperatures 482-20315 482-21759 Poststimulatory auditory adaptation in humans ATBOPHI according to computer audiometry ' Oltrastructure of blood vessels and muscle fibers A82-21791 of rat skeletal muscles after flights aboard 4 study of the acoustic reflex as elicited by Cosaos-605 and Cosmos-782 biosatellites selected environmental noise stimuli N82-17835 N82-17858 AXXBBXIOB Human auditory brainstem electric responses to Control and automatic processing daring tasks binaural and monaural stimuli requiring sustained attention - 4 neu approach H82-17861 to vigilance ADXOHAXIC COSTBOL 482-19225 Control and automatic processing during tasks ATTITUDE (IBCLIIAXI01) requiring sustained attention - A new approach Phenomena of fluctuation of human reaction to to vigilance autiorthostatic position 482-19225 H82-16721 Development of an automatic data bank for managing AODIO FBBQOEBCIES physical education of students Peculiarities of the middle ear structure in A82-21816 rodents as an index of the frequency tuning of Human-machine interface issues in the their auditory system Hultisatellite Operations Control Center-1 A82-21714 (BSOCC-1) AODIO10GX [HASA-TH-83826] H82-17875 Characteristics of the structure and functions of AUTOMOBILE ACCIDEBTS the middle ear of lizards Review of literature and regulation relating to 482-21823 thoracic impact tolerance and injury criteria AODIOBEXBI [PB82-1086S7] H82-16736 Poststimnlatory auditory adaptation in humans AOTOHOBIC BEBVOOS SISTBH according to computer audiometry The state of the vegetative functions during sleep 482-21791 A82-21771 Methods for diagnosing bearing loss in workers The relationship between cardiac and motor exposed to high noise levels in accordance with components of a conditioned reflex upon the state standards local cooling of various zones of the cerebral 482-21793 cortex in cats Hygienic standards for industrial noise A82-21787 482-21794 Acute experimental emotional stress in rabbits Temporal integration of acoustic power for /physiological and cytochemical aspects/ interrupted stimuli at suprathresbcld levels A82-21825 N82-17856 Cerebral hemispheric activity and automonic AOOIXOBI DEFECTS nervous function The functional condition of the ampullar apparatus N82-17868 in Beniere's disease 482-20308 Methods for diagnosing hearing loss in workers B exposed to high noise levels in accordance with B-52 AIBCB4FT state standards The semi-automatic instructional system of 482-21793 B-52 weapon system trainers AOOIXOBI PBBCBPTIOH A82-20539 Functional model of the conversion of stationary BACTEBI4 signals in the auditory analyzer Comets - 4 vehicle for pauspermia 482-21703 482-20868

1-5 BiLAiCB SUBJECT IB DEI

BALABCB Distinctions of regeneration of confined Positions/ movements and equilibrium of cats after atmosphere by means of photosynthesis of flights aboard biosatellites unicellular algae H82-16713 H82-16720 BABOBBCBPTOHS Phenomena of fluctuation of human reaction to Summated circulator; responses of thermal and antiorthostatic position baroreflexes in humans H82-16721 A82-21933 Eesults of study of hemodynamics and phase BBHAflOB structure of the cardiac cycle during functional The dynamics of forming a prediction system in test with lover body negative pressure during goal-directed behavior 110-day Salyut-6 station flight 482-21730 H82-16722 Change in the nature of the psychotropic effect on BIOCBEHISIBI the emotional reactivity and behavior in stress Ben data on abiogenic synthesis of prebiological situations depending on the state of the compounds in volcanic processes catecholaminergic systems of the brain A82-20017 A82-21739 Bioenergetic characteristics of various kinds of BETA PAHTICLBS physical loads Asymmetrical radical formation in beta-irradiated 482-20334 D- and L-alanines The role of analytical procedures in the formation A82-20949 of biochemicals from experiments simulating the BIBLIOGBAPHIES chemical evolution of primeval earth Human reactions to elf electric and magnetic A82-20927 fields: An annotated bibliography of current Chemical evolution of model systems of primeval literature earth periphery and thermal polymerisation of [PB82-102567] B82-16737 aqueous solutions of cyanides BICICLE 482-20933 The application of bicycle ergometry to the early The appearance of protobiopolymers and detection of ischemic heart disease protomembranes in accordance with the 'cold A82-21775 theory' of the origins of life EISADEAL HEAEIBG 482-20936 Human auditory brainstem electric responses to Emergence of flavin catalysis - An approach based binanral and monaural stimuli on the concept of bioorganic evolution 1182-17861 482-20964 BIOACOOSTICS Selective acylability of amino acids by Auditory depth perception - localization of non-enzymic model reactions of biochemical nonmoving and moving sound sources transacylations A82-21727 A82-20965 Features of the reaction to noise of the spinal On the origin of photosyuthetic enkaryotic cells - capillaries of unite rats Cyanidium caldarinm as a 'bridge* alga between A82-21767 prokaryotic cyanobacteria and eukaryotic Characteristics of the structure and functions of rhodophytes: Evidence 'from environmental, the middle ear of lizards polysaccharide biochemistry and ultrastrnctural A82-21823 studies BIOASTBOBAUTICS 182-20973 OSSB report: Space biology and aerospace Could the biochemical metabolism be different medicine, volume 15, no. 6, November - December A82-20976 1981 Differentiation of muscles on the basis of tJPBS-79849] H82-16704 trace-element composition Question of redistribution of blood in orthostatic A82-21704 position The dynamics of protein and nucleic acid content S82-16705 in rat raphe nucleus cells after total Bays and means of maintaining heat balance in deprivation of sleep /in a rotating cylinder/ pilots and cosmonauts and selective deprivation of its paradoxical phase 882-16706 A82-21718 Systemic and cerebral hemodynamics in flight The correlation between hematologic and personnel exposed to moderate hypozia biochemical indicators in the turtles Testndo B82-16707 horsfieldi Effect of transmeridional flights .on biorhythm of 482-21733 zone formation by Streptomyces levoris Metatolic change in test animals as an indicator B82-16711 of the biological effect of an electromagnetic simulation of some of man's movements in different field having a freguency of 50 Hz gravity fields 482-21758 H82-16712 The multiple forms of tyrosine aminotransferase in Positions, movements and eguilibrinm of rats after rat liver cells and their role in cellular flights aboard biosatellites homeostasis H82-16713 482-21807 Cytokinetic evaluation of erythropoiesis during Comparative biochemistry and metabolism. Part 2: long-term orbital flights naphthalene lung toxicity H82-16715 £40-4107673] B82-17812 Borepinephrine and enzymes of synthesis and Cytologic and biochemical genetic effects of degradation thereof in the rat hypothalamns chemical carcinogens following flight aboard the Cosmos-936 [AD-4107615] B82-17864 biosatellite Comparative biochemistry and metabolism. Part 1: H82-16716 Carcinogenesis Hygienic principles of ongoing monitoring of [AD-A107614] 882-17865 quality of recycled water during space flights BIOCOBP4IIBJLITI H82-16717 Disturbances in biological rhythms as a result of lexicological and hygienic aspects of improving a conflict of incompatible stimuli additional purification of vater reclaimed from 482-21720 urine BIOCOHTBOL SISTEHS B82-16718 The role of biofeedback in the adaptive regulation Possible use of house fly larvae for utilization of pathological bioelectric brain activity of organic waste in biological life-support 482-20328 systems Pulmonary shunting and its regulation N82-16719 482-21728

1-6 SOBJBCX IBDBI BIOLOSIC4L BfOLOTKMt

A histochemical investigation of the microvascular Particular features of conditioned effectors regulating the supply of blood to the electrodefensive reflex in white rats on cerebral cortex background of constant magnetic field A82-21744 H82-17851 A three-dimensional model for the arrangement of Mortality in acute myocardial infarction as the vascular and tabular components of the renal function of geomagnetic field activity in Yerevan osmoregulatory apparatus H82-17852 A82-21745 Effect of hypogeomagnetic field on activity of BIODIB1BICS some cerebral enzymes Functional characteristics of receptors connected B82-17853 Hith sustaining the flight of the roach BIOLOGICAL BVOL01IOI Periplaueta Americana L A neutral theory of biogenesis A82-21716 A82-20024 BIOBLBCTBICIIX Could life have evolved in cometary nuclei The role of biofeedback in the adaptive regulation A82-20025 of pathological bioelectric brain activity Comets and the origin of life; Proceedings of the 182-20328 Fifti College Par* Colloquium on Chemical Electroencephalographic correlates of the Evolution, University of Maryland, College Park, hemispheric functional asymmetry in the human MD, October 29-31, 1980 brain A82-20853 182-21451 Cometary material and the origins of life on earth The effects of emotional activation on the spatial A82-20867 synchronization of human brain biopotentials Comets - A vehicle for panspermia A82-21785 482-20868 Electrode unit for testing human H reflex Extreme environments - Are there any limits to life N82-16728 A82-20869 Human auditory brainstem electric responses to Comets and the origin of life - Bibliography binaural and monaural stimuli A82-20871 S82-17861 Origin of life; Proceedings of the Third ISSOL BIOGBOCHBBISTBI Meeting and Sixth ICOL Meeting, Jerusalem, Organic geochemistry of the Isna snpracrustals Israel, June 22-27, 1980 482-20961 A82-20901 Effect of transmeridional flights on biorhythm of Interstellar molecules and the origin of life zone formation by Streptcnyces levoris A82-20902 H82-16711 On the origin of organic molecules in interstellar BIOIISTBUHEITATIOB space and some of its consequences Waveguide technique for the calibration of 482-20904 miniature implantable electric-field probes for Comets and the origin of life use in microuave-bioeffects studies A82-20905 A82-20893 Liquid water on a planet over cosmic periods BIOLOGICAL BPFBCTS A82-20907 The biological effects cf Ion-level ionizing Abiotic organic synthesis in space radiation A82-20910 682-20146 Helanoidin polymers as possible oxygen sinks in Summary of a discussion on the problem of the the pre-biotic oceans 'biological norm' /in relation to an assessment A82-20921 of criteria of the harmfnlness of chemical Formation of energy rich phosphate in Fenton's effects/ reaction for prebiotic conditions A82-21750 A82-20922 Metabolic change in test animals as an indicator Corphyrin-like compounds genesis under simulated of the biological effect of an electromagnetic abiotic conditions field having a frequency of 50 Hz A82-20926 A82-21758 Seduction of thionucleosides - A prebiotic pathway Genetic damage in Escherichia coli K12 AB2480 by to deoxyribonucleosides broad-spectrum near-ultraviolet radiation A82-20928 A82-22200 Factors influencing the rate of non-enzymatic DSSB report: Space biology and aerospace activation of carboxylic and amino acids by ATP medicine, vol. 15, no. 5. Sep. - Oct. 1981 A82-20929 [JPBS-79346] H82-17812 Template-directed synthesis of oligoguanylic acids Effect of stationary magnetic field on the - Metal ion catalysis endocrine system A82-20932 H82-17814 The polymerization products of Oltrastructure of blood vessels and muscle fibers alpha-aminopropionitrile - The component of rat skeletal muscles after flights aboard separation using cation-exchange resin Cosaos-605 and Cosmos-782 biosatellites A82-20934 H82-17835 The cold the.ory of the origins of life - USSB report: Life sciences effects of uonionizing Assumptions for the theory and experimental electromagnetic radiation, no. 4 evidence [JPBS-79780] H82-17844 A82-20935 Effect of commercial frequency electromagnetic Polymerization of serine guanylate in the presence field on androgen function of rat tests of montmorillonite B82-17845 A82-20940 Features of metabolic disturbances in rat Quantum mechanical conformational analysis of myocardium under effect of alternating magnetic aminoacyladenylates - Implication in the origin fields of different paraaeters of life H82-17846 A82-20941 Influence of electromagnetic naves in millimeter Membrane lipids and the origin of life band on inductoprotein synthesis of A82-20943 penicillinase by staphylococcns aureus Besolution of underivatized amino acids by high H82-17847 pressure liquid chromatography, using chiral Effects on biological systems of electromagnetic elnants oscillations in millimeter range of wavelengths A82-20944 S82-17849 Possible selective adsorption of enantiomers by Current problems of radiobiology of Na-Bontmorillonite electroaagnetic radiation of radio-frequency range A82-20946 H82-17850 A mathematical method for the enumeration of doublet codes in genetic coding theory A82-20953

1-7 BIOLOGICAL HODEIS (HiTHEHillCS) SUBJECT IHDEX

Origin and evolution of the genetic code Simulation of some of man's movements .in different A82-20955 gravity fields tiie origin and evolution of the genetic code H82-16712 A82-20956 BIOLOGX Evolutionary processes of the genetic code Flow visualization techniques in medical and A82-20957 biological applications Summary of evidence for an anticodonic basis for 482-20778 the origin of the genetic code BIOHEDICAL DATA 482-20958 Conputer-aided analysis of the effect of the Primitive transfer BHA and origin of Darwinian initial narcosis on the central hemodynamics system 482-21797 A82-20959 Status of space biomedical programs Organic geochemistry of the Isua supracrustals H82-17239 482-20961 BIOHEIBICS Search for primitive replicative properties on The measurement of oxygen and carbon dioxide early pclyfeptides partial pressures in tissues by the gas depot 482-20963 method Emergence of flavin catalysis - AD approach based 482-20318 on the concept of bioorganic evolution BIOHICS 482-20964 Biped walking - Hodel problems of dynamics and Experiments on transfer of organic molecular control information into crystal lattice superstructures 482-18977 A82-20966 Coupling to solar energy: Sensitized Fhylogenetic seguence of metabolic pathways in photoreactions - The primary source of Precambrian cellular life self-organization 482-20967 A82-20968 Coupling to solar energy; Sensitized BIOPHISICS photoreactions - The primary source of Bioenergetic characteristics of various kinds of self-organization physical loads 482-20968 A82-20334 The evolution of blue-greens and the origins of Cellular mechanisms of the Frank-Starling phenomenon chloroplasts 482-21456 A82-20971 Functional model of the conversion of stationary Evolution of the rhodospirillaceae and signals in the auditory analyzer mitochondria - A vie* based on sequence data 482-21703 A82-20972 BIOSPHEBE On the origin of photosynthetic eukaryotic cells - Are comets connected to the origin.of life Cyanidiuo caldarinm as a 'bridge' alga between 482-20865 prokaryotic cyanobacteria and eukaryotic BIOSYHTHESIS rhodophytes: Evidence from environmental, Reduction of taionncleosides - A prebiotic pathway polysaccharide biochemistry and oltrastructnral to deoxyribonucleosides studies A82-20928 482-20973 Factors influencing the rate of non-enzymatic Hicrobial life in cold saline environments activation of carboxylic and amino acids by ATP A82-20S74 482-20929 Hutagens and carcinogens - Occurrence and role Template-directed synthesis of oligoguanylic acids during chenical and biological evclution - Metal ion catalysis 482-20975 482-20932 The physical activity of humans as a social and Origin and evolution of the genetic code biological problem A82-20955 482-21760 On the origin of photosynthetic eukaryotic cells - problems in the rate of evolution in biological Cyanidium caldarium as a 'bridge* alga between systems prokaryotic cyanobacteria and enkaryotic A82-21989 rhodophytes: Evidence from environmental, BIOLOGICAL HODEIS (BATHEHATICS) polysaccharide biochemistry and ultrastructural EEG description algorithm for use in clinical studies practice and studies of work capacity 482-20973 482-20304 Bat amino acid composition after flight aboard Models of a functional lapse in one hemisphere and Cosmos-1129 biosatellite o'f the neurofharmocological effects on the deep H82-17831 structures of the brain BLOOD CIBC01ATIOH A82-20325 Changes in microcircnlatory flow with respiratory The use of linear models for EEG analysis insufficiency A82-20326 482-20323 The myenteric plexus - Basic principles of Microcirculation, tolerance to physical strain, modeling neuronal organization and certain homeostasis parameters in patients 482-20337 with angina pectoris Competition, coexistence and irreversibility in 482-20324 models of early molecular evolution Features of the reaction to noise of the spinal A82-20951 capillaries of white rats The origin and evolution of the genetic code 482-21767 482-20956 Question of redistribution of blood in ortbostatic A mathematical model of cell populations with stem position cells H82-16705 482-21702 Systemic and cerebral hemodynamics in flight Ibe relationship between carbohydrate and lipid personnel exposed to moderate hypoxia metabolisms in muscle cell energetics under the N82-16707 influence of ATPase loading - Bathematical model Results of study of hemodynamics and phase 482-21706 structure of the cardiac cycle during functional The possibility of using mathematical methods for test with lower body negative pressure during predicting the results of the surgical treatment 140-day Salyat-6 station flight of patients with vasorenal hypertension H82-16722 482-21709 BLOOD COAGOLATIOI The mathematics of immunity response to viral The role of urokinase in the regulation of the intrusion fibrinolytic activity of blood under normal A82-21824 conditions 4 computational model for expiratory flow A82-21799 482-21929

1-8 SOBJECT IIDBX BBAIB

Blood fibrinogen as related to immersion in water Positions, movements and egnilibrium of rats after for seven days and short-tern space flight flights abpard biosatellites H82-17836 H82-16713 Studies on structure and function relationship in BODI TBHEBBATOBB fibrinogen Enhanced heat production in physically restrained H82-17859 rats in hypoxia BLOOD FLOI A82-19496 Changes of the aggregation and orientation Body temperature changes during the practice of g structure of blood in pulsating flow Tui-mo yoga A82-20333 A82-21213 Regional distribution of cardiac output in The effect of synaptically active drugs on the unanesthetized baboons during *Gz stress with hyperthermic effect of prostaglandin £2 in rats and without an anti-G suit A82-21711 A82-21681 Effects of temperature on the duration of arousal In vivo recording of blood velocity profiles and episodes during hibernation studies in vitro of profile alterations induced A82-2193K by known stenoses Hays and means of maintaining heat balance in [PB81-244139] H82-16738 pilots and cosmonauts The role of intestinal nerves in the nutrient H82-16706 induced intestinal hjpereaia BONE HABBOi H82-17869 The influence of some triterpenic glycosides on BLOOD PLASH4 C-14-alanine inclusion into the bone-marrow The effects of daily blood sampling on creatine cells of rats phosphokinase, aspartate aminotransferase and 482-20306 alanine aminotracsferase activities in the blood Characteristics of the relations of the primary serum of the monkey responses of the pentose phosphate pathway to A82-21811 glycolysis in the bone marrow of irradiated rats Blood seruo nuclease activity in healthy persons A82-21725 and patients with various hematological diseases Effects of dioxalim and oxamide on succinate and A82-21813 lactate dehydrogenase activities in rat liver, BLOOD PBESSOBE kidney and brain tissues and on the chromosomal Parameters of the interaction of bradykinin with apparatus of bone marrow cells cardiovascular system receptors A82-21778 A82-20332 BOiE HIIEBAL C011EIT The possibility of using mathematical methods for The role of C02 in the mechanism of the reparative predicting the results of the surgical treatment regeneration of bone tissue /a radioisotopic of patients with vasorenal hypertension study/ A82-21709 A82-21800 The effect of blood pressure in the pulmonary BBAIB artery on gas exchange in functionally The healthy, and the diseased human brain heterogeneous lungs Bussian book A82-21738 A82-18872 Summated circulatory responses of thermal and Brain monoamine oxidase activity during cold baroreflezes in humans adaptation and under the combined effects of A82-21933 cold and hyperbaric oxygenation Jugular, right atrial pressure and cerebral A82-19746 heoodynamics of healthy man submitted to Electroencephalographic correlates of the postural tests differentiation between verbal stimuli during H82-17825 natural night sleep in humans Portable medical status and treatment system A82-20315 [HASA-CB-167496] H82-17862 The use of linear models for EBG analysis A model for essential hypertension: Metabolic A82-20326 studies Electroencephalographic correlates of the S82-17867 hemispheric functional asymmetry in the human BLOOD VESSELS brain A three-dimensional model for the arrangement of A82-21454 the vascular and tubular components of the renal The structural and functional organization of the osmoregulatory apparatus ventrolateral nucleus of the thalamus A82-21745 A82-21155 Oltrastructure of blood vessels and muscle fibers Change in the nature of the psychotropic effect on of rat skeletal muscles after flights aboard the emotional reactivity and behavior in stress Cosmos-605 and Cosmos-782 biosatellites situations depending on the state of the H82-17835 catecholaminergic systems of the brain BLOOD VOLUME A82-21739 Effect of blood volume on sweating rate and body The circadian rhythm of activity of adrenergic fluids in exercising humans nerve fibers in the dura mater of rats A82-19495 A82-21743 The effects of horizontal body casting on blood Effects of dioxalim and oxamide on succinate and volume, drug responsiveness, and + Gz tolerance lactate dehydrogenase activities in rat liver, in the rhesus monkey kidney and brain tissues and on the chromosomal 482-21682 apparatus of bone marrow cells BLOB GBEBI ALGAE A82-21778 The evolution of blue-greens and the origins of The effects of emotional activation on the spatial chloroplasts synchronization of human brain biopotentials A82-20971 A82-21785 BODf FLUIDS The dynamics and physiological importance of the Effects of vasopressin administration on diuresis activation of the gamma-amino-butyric acid of water immersion in normal humans system in the brain and cardiac muscle under A82-19U91 pain and emotional stress Orthostatic fluid-electrolyte and endocrine A82-21808 responses in fainters and nonfainters Temperature dependence of alanine and aspartate A82-19H92 aminotransferase activities in rat brain during Effect of blood volume on sweating rate and body hypothermia of various durations and adrenalectomy fluids in exercising humans A82-21812 A 82-19495 Condition of meningeal nervous system during BODZ KIHEHATICS repeated exposure to transverse accelerations Simulation of some of man's movements in different H82-16730 gravity fields B82-16712

1-9 BB1IB CIBCOUIIOI SOBJBCT IIDEX

BBAI1 CIECOLA1IOH CALCIOfl SEIABOLISH Models of a functional lapse in one hemisphere and The temperature dependence of the kinetics of of the neuropharaocological effects on the deep isometric myocardium relaxation structures of the brain 482-19748 482-20325 Effect of calcium on the temporal characteristics Bespiration cf brain sjnaptosomes under conditions of muscle contraction of depolarization in rats deprived of paradoxal 482-21708 sleep Mechanisms for the regulation of the intracellular 482-20336 calcium distribution Changes in the main characteristics of the central 482-21770 hemodynamics of health; individuals and In vitro Ca-45/++/ uptake and exchange by hypertension patients during physical exercise otoconial complexes in high and low K/+/Ha/+/ 482-21111 fluids The effect of low teoperatore on the activity and 482-22249 substrate specificity of nonoamine oxidases in Begulation of calcium current and calcium activity rat brain nitochondria in heart cells 482-21735 H82-17870 A histochemical investigation of the nicrovascnlar C4LIBB4TIHG effectors regulating the supply of blood to the Waveguide technique for the calibration of cerebral cortex miniature implantable electric-field probes for 482-21744 use in microvave-bioeffects studies Echoencephalographic indices in patients vita 482-20893 hypertensive disease under the effect of CABCEB functional loads Cytologic and biochemical genetic effects of 482-21753 chemical carcinogens Phasic energy analysis of rheoencephalograns in [40-4107615] H82-17864 the detection of the decompensation of cerebral Comparative biochemistry and metabolism. Part 1: hemodynamics Carcinogenesis A82-21754 [AD-A107614] H82-17865 Certain features of cerebral hemodynamics in doing CAEI1IAHIES (4I4TOBI) mental work at different air temperatures Features of the reaction to noise of the spinal A82-21759 capillaries of white rats Effects of pyrroxane and methylapogalantamine on 482-21767 cerebral blood circulation and oxygen regime CABBOaiDBATB BEIiBOLISH A82-21776 Soae indicators of carbohydrate metabolism in rat BBAIB DABA6E lung during repeated and chronic hypoxia The role of biofeedback in the adaptive regulation 482-20302 of pathological bioelectric brain activity Change in the cytochemical indicators of 482-20328 carbohydrate metabolism in the peripheral blood Trial on the use of stabilography in the medical nentrophils of pilots supervision of boxers 482-21457 482-21817 The relationship between carbohydrate and lipid BBAIB STBB metabolisms in muscle cell energetics under the Forward masking of auditory nerve (H sub 1) and influence of ATPase loading - Mathematical model brainsteu responses (Have V) in humans A82-21706 H82-17860 Characteristics of the relations of the primary Human auditory brainsteo electric responses to responses of the pentose phosphate pathway to binaural and monaural stimuli glycolysis in the bone marrow of irradiated rats H82-17861 482-21725 BBBATHIBG Activity of some enzymes of carbonhydrate Phase V of the single-breath washout test metabolism in rat skeletal muscles after space 482-21928 flight Pulmonary gas exchange during altered density gas H82-17834 breathing Features of metabolic disturbances in rat 482-21935 myocardium under effect of alternating magnetic BBOBCBI fields of different parameters An asymmetrical model of the airways of the dog lung 882-17846 482-21926 C4BBOH BUBBLES Amino acids derivatives synthesis from nitrogen, Evaluation of safety of decompression from the carbon and water by electric discharges critical volume of gas bubbles formed in the 482-20018 organism CAEBO1 COBPOOBOS 482-21717 Bates of fixation by lightning of carbon and BOXXBIC ACID nitrogen in possible primitive atmospheres Activation of the metabolism of. the 482-20016 gamma-aminobutyric acid system in the cerebral Evolution of the terrestrial atmosphere and its hemispheres under various types of stress fossils in biosystems 4 82-217 If, 482-20960 The dynamics and physiological impprtance of the Experiments on transfer of organic molecular activation of the gamma-anino-butyric acid information into crystal lattice superstructures system in the brain and cardiac auscle under 482-20966 pain and emotional stress CABBOH DIOXIDE 482-21808 Photoassisted carbon dioxide reduction and BYPASSES formation of twoand three-carbon compounds Pulmonary shunting and its regulation prebiological photosynthesis 482-21728 482-20920 The role of C02 in the mechanism of the reparative regeneration of bone tissue /a radioisotopic study/ CADHIDH 482-21800 Mechanisms of cadmium absorption in rats Distinctions of regeneration of confined [PB82-108184J H82-16703 atmosphere by means of photosynthesis of C4LCIOH unicellular algae Some mechanisms of calcium transport by the H82-16720 cardiac sarcoleaea CABBOB DIOXIDE COHCBBTBATIOB H82-17810 Breath-by-breath measurement of true alveolar gas exchange 482-19498

1-10 SUBJECT IHBBI CELL DIVISIOH

CABfiOI DIOXIDE IBJSIOI Emotional stress as a factor in cardiovascular The role of extracellular 02 and C02 tensions in disorders membrane mechanisms of cerebral arterial smooth A82-21796 muscle regulation Evaluation of the functional state of the 482-19747 cardiovascular system in patients with ischemic The measurement of oxygen and carbon dioxide heart disease with reference to the nature of partial pressures in tissues by the gas depot their occupational activity method A82-21803 A82-20318 Acute experimental enotional stress in rabbits C4BB01 ISOTOPES /physiological and cytochemical aspects/ Comets and the origin of life - The stable isotope 482-21825 approach Sumoated circulatory responses of thermal and A82-20864 baroreflexes in humans C4BBO» flOSOXIDE A82-21933 Bate of uptake of carbon oonoxide at different Besults of study of hemodynamics and phase inspired concentrations in hunans structure of the cardiac cycle during functional 482-21930 test with lower body negative pressure during CABBOB HOIOZIOE FOISOBIBG 140-day Salyut-6 station flight Health effects of carbon monoxide and ozone H82-16722 [PB82-114265] H82-17866 Cardiac output and cardiac cycle phase structure CABB01 14 of pilots during flights The influence of some triterpenic gljcosides on 1182-17821 C-14-alanine inclusion into the bone-marrow Effects of embient parameters on man cells of rats H82-17826 A82-20306 Age related distinctions of cosmonauts regional • The role of C02 in the mechanism of the reparative heiodynamics regeneration of bone tissue /a radioisotopic 882-17829 study/ CAS3S A82-21800 The effects of horizontal body casting on blood CABBOBACEODS CHOBDBIIES volume, drug responsiveness, and +Gz tolerance Organic analysis of the Antarctic carbonaceous in the rhesus monkey chondrites A82-21682 482-20908 CATABOLISH CARB01ACEOOS HAIBBIAIS Increased excretion of urea and Could the biochemical cetabolism be different N/tau/-methylhistidine by rats and humans after 482-20976 a bout of exercise CABBOIACBOOS HBTBOBITBS A82-21927 Hitrogen compounds in carbonaceous meteorites - A CATAJ.ISIS reassessment Template-directed synthesis of oligoguanylic acids 482-20909 - Hetal ion catalysis CABBOXIL GBOOP A82-20932 Potentiometric titration behavior of polyamino On the polycondensation of amino acid adenylates acids prepared by thermal polycondensation on montmorillonites A82-20938 A82-20939 CABBOXIIIC ACIDS Emergence of flavin catalysis - An approach based Pactors influencing the rate of non-enzymatic on the concept of bioorganic evolution activation of carboxylic and anino acids by 41P A82-20964 482-20929 CATAIITIC ACSITI1I CABCIBOGEIS Clays as prebiotic photocatalysts The biological effects of low-level ionizing 482-20916 radiation Template-directed synthesis of oligoguanylic acids 482-20116 - Hetal ion catalysis flutagens and carcinogens - Occurrence and role 482-20932 during chenical and biological evolution Terrestrial evolution of polymerization of amino A82-20975 acids - Heat to ATE Cytologic and biochemical genetic effects of 482-20937 chemical carcinogens Polymerization of serine guanylate in the presence [AD-4107615] H82-17864 of montaorillonite Comparative biocheaistry and metabolism. Part 1: 482-20940 Carcinogenesis Histidyl-histidine catalysis of glycine [4D-4107614] 882-17865 condensation in fluctuating clay environments CABDIAC ADBIC1ES 482-20952 Alterations in responses to drugs of atria from Experiments on transfer of organic molecular white rats acclimated to hypobaric hypoxia information into crystal lattice superstructures 482-19497 A82-20966 CABDIAC VBBXBICLES CATECaOLAHIIB Begulation of calcium current and calcium activity Activation of succinate dehydrogenation in rat in heart cells liver by noradrenalin, cAHP and acute cooling H82-17870 AS2-21734 CABDIOGB4PHI Change in the nature of the psychotropic effect on Informativeness of ultrasonic Doppler cardiograph/ the emotional reactivity and behavior in stress in evaluation of coronary circulation situations depending on the state of the H82-17828 catecholaminergic systems of the brain CABDIOLOGI 482-21739 The dynamics of heart rate recovery following work CAIIOIS of various aerobic intensities Mechanises for the regulation of the intracellular A82-21815 calcium distribution CABDIO?ASCOLAB SISTEH 482-21774 Parameters of the interaction of bradykinin with C4TS cardiovascular system receptors Condition of meuingeal nervous system during A82-20332 repeated exposure to transverse accelerations Cardiovascular origins of heatstroke K82-16730 pathophysiclogy - An anesthetized rat model CELL DIVISIOH A82-21687 4 mathematical model of cell populations with stem Investigation and evaluation of cardiac cells arrhythmias in healthy young persons 482-21702 A82-21710 An electron microscope study of hyperplasia in The state of the vegetative functions during sleep fibers of the skeletal muscles of athletes A82-21771 482-21764

1-11 CELLS (BIOLOGY) SOEJECT IIDEI

The source of reparative regeneration in skeletal Certain features of cerebral hemodynamics in doing muscle tissue mental work at different air temperatures 482-21768 482-21759 Approaches to the removal of G2-chalone from the Cerebral heaispheric activity and automonic liver of rats nervous function 482-21810 S82-17868 CELLS (BIOLOGI) CH4BGB IB4HSFBB The influence of some triterpenic glycosides. on Stereoselective interactions of snail biological C-14-alanine inclusion into the bone-marrow molecules cells of rats 482-20945 482-20306 CBEM1C4L BOIDS Phylogeoetic sequence of metabolic pathways in Clays as prebiotic photocatalysts Precambrian cellular life 482-20916 482-20967 Evolving nucleotide binding surfaces DH4-protein complex frcn an eztreoe halopbile - 4 482-20954 histone-like protein in archaebacteria CBEBIC4L COHPOSITIOI 482-20970 Investigation of the otolithic membrane of the On the origin of photosynthetic eukaryotic cells - utricle of the guinea pig Cyanidiua caldarina as a 'bridge* alga between 482-20301 prokaryotic cyanobacteria and eukaryotic Chemical evolution of interstellar dust - 4 source rhodophytes: Evidence froa environmental, of prebiotic material polysaccharide biocheaistry and ultrastructural 482-20863 studies Comets and the origin of life - The stable isotope 482-20973 approach Cellular mechanisms of the Frank-Starling phenomenon 482-20864 482-^21456 Are comets connected to the origin of life Changes in the structure and cellular composition 482-20865 of the inguinal lynph nodes of white rats The role of analytical procedures in the formation subjected to static and dynamic stresses of biochemicals from experiments simulating the 482-21761 chemical evolution of primeval earth Cellular and molecular bases of local immunity 482-20927 482-21773 Approaches to the removal of G2-chalone from the Mechanisms for the regulation of the intracellular liver of rats calcium distribution 482-21810 482-21774 Chemicals Identified in Human Biological Bedia The existence of an endogenous biorhythm in [DE81-030813] H82-16735 chromatic-positive cells of the buccal CHEHIC4L COSPOOBDS epithelium in women Cytologic and biochemical genetic effects of 482-21783 chemical carcinogens The multiple forms of tyrosine aminotransferase in [AD-4107615] H82-17864 rat liver cells and their role in cellular CBBBICAL EFFECTS homeostasis Summary of a discussion on the problem of the 482-21807 'biological norm* /in relation to an assessment 4 hydrodynamic model of an outer hair cell of criteria of the harmfulness of chemical [H4S4-TB-82773] H82-16743 effects/ Some mechanisms of calcium transport by the 482-21750 cardiac sarcclemma CHEBIC4L EVOLOTIOI H82-17810 4 model for the ehantiomeric enrichment of CEITBAl IBBVOOS SISTBB polypeptides on the primitive earth Computer-aided analysis of the effect of the 482-20020 initial narcosis on the central hemodynamics Search for effect of longitudinally polarized 482-21797 protons on optically active amino acids Stationary magnetic fields and reticular 482-20021 influences on adrenergic and cholinergic systems 4 neutral theory of biogenesis 1182-16725 482-20024 CBBBBH4L COBIBX Could life have evolved in cometary nuclei Frequency characteristics of visual evoked 482-20025 potentials in different regions of the human Comets and the origin of life; Proceedings of the cerebral cortex Fifth College Park Colloquium on Chemical 482-20314 Evolution, University of Maryland, College Park, Models of a functional lapse in one hemisphere and BD, October 29-31, 1980 of the neuropharmocological effects on the deep 482-20853 structures of the brain Chemical evolution of interstellar dust - 4 source 482-20325 of prebiotic material 4 histochemical investigation of the microvascular 482-20863 effectors regulating the supply of blood to the Comets and the origin of life - The stable isotope cerebral cortex approach 482-21744 482-20864 Heuronal-glial alterations in the cerebral cortex Are comets connected to the origin of life of animals under the influence of white noise 482-20865 482-21769 Cometary material and the origins of life on earth The relationship between cardiac and ootor 482-20867 components of a conditioned reflex upon the Comets and the origin of life - Bibliography local cooling of various zones of the cerebral 482-20871 cortex in cats On the origin of organic molecules in interstellar 482-21787 space and some of its conseguences Huscle, motor cortex, cerelellar nuclear, and 482-20904 spindle afferent during slow hold-ramp-hold Comets and the origin of life position-tracking movements of the monkey's wrist 482-20905 H82-17854 nature and origin of organic molecules in comets CEBEBBDB 482-20906 The role of extracellular 02 and C02 tensions in Organic analysis of the Antarctic carbonaceous aembrane mechanisms cf cerebral arterial smooth chondrites nuscle regulation 482-20908 482-19747 nitrogen compounds in carbonaceous meteorites - 4 Activation of the metabolism of the reassessment gamoa-aninobntyric acid system in the cerebral 482-20909 hemispheres under various types of stress 482-21746

1-12 SUBJECT I1D1I CLAIS

Formation of prebiotic precursors from model Search for primitive replicative properties on reducing atmospheres Bole of hydrogen escape early polypeptides 482-20911 A82-20963 Organic chemical evolution of reducing aodel of Evolution of the rhodospirillaceae and the atnosphere of the primitive earth - Bole of mitochondria - 4 view based on sequence data 0V light and electric discharges 482-20972 482-20912 Butagens and carcinogens - Occurrence and role Far 0V photolysis of methane-water gaseous during chemical and biological evolution aiitures and the prebiotic synthesis of aldehydes 482-20975 482-20913 Could the biochemical metabolism be different Possible cole of phosphine in chemical evolution 482-20976 A82-20915 CHBHICAI FBACIIOHAIIOI Clay-mediated reactions of BCH oligomers - The HCS oligomerization - Isolation and preliminary effect of the oxidation state of the clay characterization of a nev precursor of adenine A82-20917 A82-20930 Chemical evolution and plate tectonics The polymerization products of 482-20918 alpha-aminopropionitrile - The component The Strecker synthesis in the primitive ocean separation using cation-exchange resin chemical evolution A82-20934 482-20919 CBBHICAL BBACXIOBS Foraation of energy rich phosphate in Fenton's Possible mechanism for chemical induction of reaction -— for prebiotic conditions chromosome aberrations in male meiotic and 482-20922 postmeiotic germ cells of mice Synthesis and degradation of anino acids by [DB81-031999] H82-16700 contact glow discharge electrolysis, a possible CHLOBIBB COHPOOHDS • route for prebiotic formation of bio-organic Comparative evaluation of antimicrobial activity compounds of some urine preservatives 482-20924 H82-17830 Genesis of amino acids in the primeval sea - CBLOHOPBT.L1S Formation of amino acids from sugars and ammonia The structure and function of chlorophyll-proteins in a modified sea medium in photosystem 1 and the light harvesting 482-20925 complex of photosystem 2 The role of analytical procedures in the formation H82-17811 of biochemicals from experiments simulating the CBLOBOPL4S1S chemical evolution of primeval earth The evolution of blue-greens and the origins of 482-20927 chloroplasts HCH oligomerization. - Isolation and preliminary 482-2097J characterization of a new precursor of adenine CBOLIRB 482-20930 The effect of cholinomimetics on the development Cyanaaide mediated syntheses of leu, ala, and phe of hypothermia peptides under plausible primitive earth 482-21781 conditions CHOLIHEBGICS 482-20931 Stationary magnetic fields and reticular Chemical evolution of model systems of primeval influences on adrenergic and cholinergic systems earth periphery and therial [olymerisation of H82-16725 agueous solutions of cyanides CHBOB4IOGB4PHY 482-20933 4 model for essential hypertension: Hetabolic She cold theory of the origins of life - studies Assumptions for the theory and experimental H82-17867 evidence CHBOHOSOHBS 482-20935 Possible mechanism for chemical induction of The appearance of protcbiopolymers and chromosome aberrations in male meiotic and protomembranes in accordance with the 'cold postmeiotic germ cells of mice theory' of the origins of life £OB81-031999] H82-16700 482-20936 CIBCADIAB BHITHHS Terrestrial evelation of polymerization of amino The circadian rhythm of activity of adrenergic acids - Heat to 4TF nerve fibers in the dura oater of rats 482-20937 482-21743 On the polycondensation of amino acid adenylates Dynamics of the condition of granulation tissue on montmorillcnites after injuries sustained at different times of 482-20939 the day Environmental conditions for the formation of 482-21763 marigranules and kinetic studies on the formation The existence of an endogenous biorhythm in chemical evolution of aoino acids in sea chromatin-positive cells of the buccal medial epithelium in women 482-20912 482-21783 Membrane lipids and the origin of life Comparative study of several physiological 482-20943 parameters in the evaluation of functional Besolution of underivatized amino acids by high condition in nurses pressure liquid chromatcgraphy, using chiral &82-21826 eluants CIVII. AVIATIOB 482-20944 Effects of relative metabolic rate and heart rate Stereoselective interactions of small biological variation on the performance of flight attendants molecules 482-21680 482-20945 Causes of fatigue among crews of civil aviation Competition, coexistence and irreversibility in helicopters models of early molecular evolution H82-16708 482-20951 CLAIS Evolving nucleotide binding surfaces Clays as prebiotic photocatalysts 482-20954 482-20916 Summary of evidence for an anticodonic basis for Clay-mediated reactions of HCN oligomers - The the origin of the genetic code effect of the oxidation state of the clay 482-20958 482-20917 Evolution of the terrestrial atmosphere and its Bistidyl-histidine catalysis of glycine fossils in biosystems condensation in fluctuating clay environments 482-20960 482-20952 Secondary structures of pclypeptides as evolutionary growing points 482-20962

1-13 CUBICAL BBDICIiB SOBJBCT IBDEI

CUBICAL HBDICIIB COLO PLASHAS EEG description algorithm for use in clinical The cold theory of the origins of life - practice and studies of work capacity Assumptions for the theory and experimental A82-20304 evidence The functional condition of the ampnllar apparatus A82-20935 in Heniere's disease The appearance of protobiopolymers and 482-20308 protomembraues in accordance with the 'cold Deontology in the practice of otorhinolaryngology theory1 of the origins of life A82-20312 482-20936 Special and clinical physiology of hypoxic states COLD TOLEBABCB 482-20317 Adaptation to high-altitude hypoxia at different Elevation of hypoxia resistance with the use of ambient temperatures /before and during gutiBine adaptation/ 482-20319 482-21715 Some indicators of protein netabolisa in COLLAGBIS erythrocytes daring radiation sickness and Dynamics of the condition of granulation tissue following cystamine injection after injuries sustained at different times of A82-21724 the day Clinical results on thymectcmy in patients with A82-21763 myopathy in relation to the degree of muscular COLOB VISIOB weakness psychophysical evidence for more than two kinds of 482-21755 cone in dichromatic color blindness Mechanisms of compensation and adaptation in 482-19608 relation to the hyperfunction of the heart COBBAf 482-21756 Acceleration induced voltage variations in the The role of nrokinase in the regulation of the electrocardiogram during exhaustive simulated • fibrinolytic activity of blood under nornal aerial combat maneuvering conditions 482-21683 482-21799 COMET HOCIEI Predicting the potentials of young swimmers based Could life have evolved in cometary nuclei on clinical and physiological data 482-20025 A82-21814 Bature and origin of organic molecules in comets COAGULATIOB 482-20906 Biophysical fundamentals and instrumentation for COMETS the endovesical Bd:YAG-laser application Coiets and the origin of life; Proceedings of the tuaor therapy Fifth College Park Colloquium on Chemical [HBB-OA-581-81-0] H82-17843 Evolution, University of Maryland, College Park, COAXIAL CABLES flD, October 29-31, 1980 Measurement of radio frequency permittivity of 482-20853 biological tissues vith an open-ended coaxial Cosets and the origin of life - The stable isotope line. I approach A82-20891 482-20864 Measurement of radio frequency permittivity of Are comets connected to the origin of life biological tissues vith, an open-ended coaxial A82-20865 line. II - Experimental results Comets and the photochemistry of the paleoatmosphere A82-2C892 482-20866 COCHLEA Cometary material and the origins of life on earth Cochlear analysis of sound intensity and some 482-20867 mechanisms of auditory sensations Coiiets - 4 vehicle for panspermia 482-21792 482-20868 COCKPITS Extreme environments - Are there any limits to life Physiological and hygienic evaluation of vibration A82-20869 in the cockpit of a cargo helicopter Comets and the origin of life - Bibliography B82-16709 482-20871 COCKBO1CBBS Comets and the origin of life Functional characteristics of receptors connected 482-20905 with sustaining the flight of the roach COMFOB1 Periplaneta Americana L An evaluation of helicopter noise and vibration 482-21716 ride qualities criteria COGBITIOB [HASA-TH-83251] H82-17871 An analysis of cognitive mapping skill COHPOfAXEOBAL FLUID DIBABICS [AD-A106145] B82-16740 4 computational model for expiratory flow COLO ACCLIflATIZATIOH 482-21929 Glycogen and nonspecific adaptation to cold COMPUTES ASSISTED IBSTBOCTIOB 482-19494 Development of the Automated Performance Brain monoamine oxidase activity during cold Assessment and Bemedial Training System adaptation and under the combined effects of (4P4BTS): 4 landing signal officer training aid cold and hyperbaric oxygenation [40-4106224] H82-17873 482-19746 COMPOTES TECHHIQDES The influence of muscular work on the vestigial Microelectronics and computers in medicine effects of ccld acclimation 482-21268 482-19749 Poststimnlatory auditory adaptation in humans Hicrobial life in cold saline environments according to computer audiometry 482-20974 482-21791 The effect of cold stress on the level and Computer-aided analysis of the effect of the activity of micrcsomal cytochrome F-450 in the initial narcosis on the central hemodynamics rat liver 482-21797 482-21732 COMPUTERIZED SIBOLATIOB Peroxidation of lipids in the liver and lungs of Computer simulation as a visual aid in a video rats during prolonged adaptation to the cold course —• for ATC system performance 482-21736 A82-19248 Lysosomes under conditions of stress Advanced aviation concepts evaluation through A82-21770 computer driven simulation human factors LOB isoenzyme spectrum in intact and denervated consideration in flight training simulator design skeletal muscles of rats of various age during A82-19258 cold adaptation A82-21798

1-14 SOBJECT IBDEI DECISION THEOBI

COIDITIOBED BEPLEXES CBITBBIA The effect of the motor activity regime on the An evaluation of helicopter noise and vibration development, conservation, and regeneration of ride qualities criteria defensive conditioned reflexes in rats £BASA-TB-83251J H82-17871 482-20305 CBDDB OIL The. relationship between cardiac and motor Hicrobiologically-mediated mntagenic activity of components of a conditioned reflex upon the crude oil local cooling of various zones of the cerebral [PB82-105131] B82-16702 cortex in cats CBISZAL LAStlCES A82-21787 Experiments on transfer of organic molecular Particular features of conditioned information into crystal lattice superstructures electrodefensive reflex in white rats on A82-20966 background of constant magnetic field CYAJA BIDES H82-17851 Cyanamide mediated syntheses of leu, ala, and phe COIPBBBICBS peptides under plausible primitive earth Comets and the origin of life; Proceedings of the conditions Fifth College Park Colloquium on Chemical A82-20931 Evolution, University of Maryland, College Park, CIABIDES BD, October 29-31, 1980 Chemical evolution of model systems of primeval 482-20853 earth periphery and thermal polymerisation of Origin of life; Proceedings of the Third ISSOL agneous solutions of cyanides Meeting and Sixth ICOL Meeting, Jerusalem, A82-20933 Israel, June 22-27, 1980 CYCLIC COBPOUSDS A82-20901 Emergence of flavin catalysis - An approach based DOT/FAA Human Factors Workshop on Aviation. on the concept of bioorganic evolution Transcript, vol 1 A82-20964 [AD-1107802] S82-17876 CISIBABISB DOT/FAA Human Factors workshop on Aviation. Some indicators of protein metabolism in Transcript, volume 2 erythrocytes during radiation sickness and [AD-A107803] B82-17877 following cystamine injection COITBACXIOB A82-21724 Effect of calcium on the temporal characteristics CIIOCBBOBES of muscle contraction The evolution of blue-greens and the origins of A82-21708 chloroplasts COBTBOL SIHU1ATIOB A82-20971 Computer simulation as a visual aid in a video The effect of cold stress on the level and course for ATC system performance activity of microsooal cytochrome P-450 in the A82-19248 rat liver COBTBOL THEOBI A82-21732 Time domain identification of an optimal control Succinate dehydrogenase and cytochrome oxidase pilot model with emphasis on the objective activity in tissues of rats submitted to function long-term hypokinesia £HASA-CB-168*87] H82-17874 N82-16723 COBIOLIS EFFECI CTTOGEBESIS Posturography of ataxi a induced by Coriolis- and Changes in morphological and cytogenetic Purkinje-effects hematopoietic indicators in hamadryas baboons A82-21684 exposed to chronic low-level radiation COBIEA A82-21726 Differences in eye movement data recorded by CITOLOSY electro-oculography and corneal reflection The source of reparative regeneration in skeletal techniques Buscle tissue A82-19224 A82-21768 COBOBABX ABTBBI DISEASE Possible mechanism for chemical induction of The effects of daily blood sampling on creatine chromosome aberrations in male meiotic and phosphokinase, aspartate aminotransferase and postueiotic germ cells of mice alanine aminotransferase activities in the blood [DE81-031999] H82-16700 serum of the monkey Cytologic and biochemical genetic effects of A82-21811 chemical carcinogens COBOBABI CIBCOLATIOB [AD-A107615] H82-17864 Informativeness of ultrasonic Doppler cardiography in evaluation of coronary circulation H82-17828 COSBIC DOST DATA BASES Comets and the origin of life - The stable isotope Bicroelectronics and computers in medicine approach A82-21268 482-20864 Development of an automatic data bank for managing COSHOCHEBISTBY physical education of students Possible impact of cosaochemistry on terrestrial A82-21816 biology - Historical introduction DATA PBOCBSSIBG A82-21987 Control and automatic processing during tasks COSBOBA01S requiring sustained attention - A new approach iays and means of maintaining heat balance in to vigilance pilots and cosmonauts A82-19225 N82-16706 DATA STOBAGE COSHOS SATELLITES Development of an automatic data bank for managing Status of space biomedical programs physical education of students B82-17239 482-21816 CBASHES DECISIOH BAKIBG Beview of literature and regulation relating to Microelectronics and computers in medicine thoracic impact tolerance and injury criteria A82-21268 [PB82-108697] B82-16736 Choosing among alternatives with uncertain CBEATIBE outcomes: Effect of prior curing and estimation The effects of daily blood sampling on creatine requirements phosphokinase, aspartate aminotransferase and [AD-A106143] H82-16739 alanine aminotransferase activities in the blood DECISIOB THBOBY serum of the monkey Choosing among alternatives with uncertain A82-21811 outcomes: Effect of prior curing and estimation requirements [AD-A106143] H82-16739

1-15 DBCODIIG SUBJECT IHDEX

DBCODIHG DIOBB1ICS A mathematical method for the enumeration of Effects of vasopressin administration on diuresis doublet codes in genetic coding theory of water immersion in normal humans' A82-20953 482-19491 DECOBPBESSIOH SICBBBSS DB06S Evaluation of safety of decompression from the The effect of piracetam on the body's resistance critical volume of gas bubbles formed in the to hypoxia organism 482-21777 482-21717 The effect of the prolonged administration of Air embolism - Possible rcle of surfactant on sodium hydroxybutyrate on the physical work recompression capacity and muscle tissue state of rats A82-21931 482-21779 DBGBADATIOi Chemicals Identified in Human Biological Media Norepiuephrine and enzymes of synthesis and [DE81-030813] B82-16735 degradation thereof in the rat hypothalamus DIBAflIC CHABACTEBISIICS following flight aboard the Cosmos-936 The dynamics of forming a prediction system in biosatellite goal-directed behavior B82-16716 A82-21730 DBHIDBAIBD FOOD DIIAUC CCHIBOL Amino acid metabolism during prolonged intake of Biped walking - Hodel problems of dynamics and dehydrated foods and simulation of some space control flight factors 482-18977 B82-17816 Development of an integrated walking robot DBHTDBOGBI4XIOB A82-18988 Activation of succinate dehydrogenation in rat DTBiHIC BBSPOBSB liver by noradrenalin, c4HP and acute cooling In vitro Ca-45/+*/ uptake and exchange by A82-21734 otoconial complexes in high and low K/+/Ba/+/ DEOXIBIBQHOCLEIC ACID fluids OHA-proteiu complex from an extreme halophile - A A82-22249 histone-like protein in archaebacteria DIBAHIC STABILITY A82-20970 Development of an integrated walking robot Genetic damage in Escherichia coli K12 4B2480 by 482-18988 broad-spectrum near-ultraviolet radiation A82-22200 Cytologic and biochenical genetic effects of chemical carcinogens BAB [4D-4107615] B82-17864 The functional condition of the ampnllar apparatus DBPOLABIZAMOB in Heniere's disease Respiration of brain synaitosomes under conditions 482-20308 of depolarization in rats deprived of paradoxal A hydrodynamic model of an outer hair cell sleep [SASA-TH-82773] B82-16743 A82-20336 EABDBOflS DBSEBIS Characteristics of the structure and functions of Physical performance tasks reguired of 0. S. the middle ear of lizards Marines operating in a desert environment A82-21823 [AD-A107866] H82-17863 EATIBG DIAGNOSIS Comparative antihypoxic efficacy of pressure Detection of amblyopia utilizing generated retinal chamber conditioning and fasting of man reflexes H82-16729 [BASA-CB-161944] H82-16732 ECBOEBCEPHALOGBAPHI DIETS Echoencephalographic indices in patients with In-flight diets and quantitative adequacy thereof hypertensive disease under the effect of to pilot expenditure functional loads H82-17813 482-21753 DXFFOSIOH BCOSISIBHS Facilitated diffusion of small non-electrolytes in Introduction prognosis and its methodological the human red blood cell aspects plant growth in new habitats B82-17855 A82-21722 DIGITAL COHPUTEBS BDOCAXIOB Microelectronics and computers in medicine The physical activity of humans as a social and 482-21268 biological problem DIGITAL SlflULATIOB A82-21760 VTOL/STOL visual study Development of an automatic data bank for managing (BASA-CB-166292] H82-17872 physical education of students DIGITALIS A82-21816 Regulation of calcium current and calcium activity Rationalizing physical regimen of sedentary workers "in heart cells 482-21818 H82-17870 BFFBBBH1 BBBVOOS SISTEBS DISEASES The effect of the motor activity regime on the The functional condition of the ampnllar apparatus development, conservation, and regeneration of in Heniere's disease defensive conditioned reflexes in rats 482-20308 A82-20305 DISPLAY DEVICES A systems analysis of human motor reactions in Visual technology and the future for flight various modes of operation of goal-directed simulators behavioral acts 482-20538 A82-21729 VTOL/STCL visual study The relationship between cardiac and motor [BASA-CB-166292] B82-17872 components of a conditioned reflex upon the DIDBBSIS local cooling of various zones of the cerebral Effects of vasopressin administration on diuresis cortex in cats of water immersion in normal humans A82-21787 482-19491 BLBCTBIC DISCHABGES The role of natrinresis in the prophylactic effect Amino acids derivatives synthesis from nitrogen, of adaptation to hypoxia in the case of carbon and water by electric discharges hereditary hypertension A82-20018 482-21712 Organic chemical evolution of reducing model of the atmosphere of the primitive earth - Bole of DV light and electric discharges A82-20912

1-16 SOBJECX IIDBX EiDOCBIBE SBCBETIOHS

ELBCTBIC FIELDS BLECIBOBAGHBIIC BADIATIOH ttavegaide technique for the calibration of OSSB report: Life sciences effects of nonionizing miniature inplan table electric-field probes for electromagnetic radiation, no. 4 use in microvave-bioeffects studies [JPBS-79780] 1182-17844 .282-20893 Effect of commercial frequency electromagnetic Human reactions to elf electric and nagnetic field on androgen function of rat tests fields: in annotated bibliography of current M82-17845 literature Features of metabolic disturbances in rat [PB82-102567] S82-16737 myocardium under effect of alternating magnetic ELECTBIC EOTBHTIAL fields of different parameters Acceleration induced voltage variations in the H82-17846 electrocardiograa daring exhaustive siaulated Influence of electcoaagnetic waves in millimeter aerial combat maneuvering band on inductoprotein synthesis of A82-21683 penicillinase by staphylococcus aureus ELECIBIC POBEB JBAISBISSIOH H82-17847 Effect of commercial frequency electromagnetic Effects on biological systems of electromagnetic field on andxogen function of rat tests oscillations in millimeter range of wavelengths 1182-17845 H82-17849 ELECTBIC SXIBOLI Current problems of radiobiology of Acute experimental emotional stress in rabbits in electromagnetic radiation of radio-frequency range a modulated electromagnetic field H82-17850 A82-20307 Particular features of conditioned Acute experimental emotional stress in rabbits electrodefensive reflex in white rats on /physiological and cytochemical aspects/ background of constant magnetic field A82-21825 H82-17851 ELECIBIC BIBB Mortality in acute myocardial infarction as The thermal response of a human in the near-zone function of geomagnetic field activity in Yerevan of a resonant thin-Hire antenna 882-17852 A82-22206 Effect of hypogeomagnetic field on activity of ELBCXBOCABDIOGBAPBI some cerebral enzymes Acceleration induced voltage variations in the 1182-17853 electrocardiogram during exhaustive simulated ELECTBOBXQGBAPBI aerial combat maneuvering Study of the electrical activity of the A82-21683 extraocnlar muscles Investigation and evaluation of cardiac A82-21731 arrhythmias in healthy young persons BLBCSBOB BTCBOSCOPBS A82-21710 An electron microscope study of hyperplasia in Portable medical status and treatment system fibers of the skeletal muscles of athletes [HASA-CB-167496] H82-17862 A82-21764 ELECIBODBS BLBCTBOBISTAGflOGBAPBI Electrode unit for testing human H reflex Differences in eye movement data recorded by H82-16728 electro-oculography and corneal reflection ELBCIBOEBCBPBALOGBAPH7. techniques EEG description algorithm for use in clinical A82-19224 practice and studies of work capacity EBEBGBBCIBS A82-20304 First aid for thorax traumas: Thorax drainage Electroencephalographic correlates of the through suction - Beport on 25 cases differentiation between verbal stimuli during A82-19016 natural night sleep in humans BBOXIOBAL FACTOBS A82-20315 Acute experimental emotional stress in rabbits in The use of linear models for EEG analysis a modulated electromagnetic field A82-20326 A82-20307 Electroencephalographic correlates of the Contractile dysfunction of vascular wall smooth hemispheric functional asymmetry in the human muscle under emotional nociceptive stress brain A82-20322 A82-21454 Functional condition of the rat sympato-adrenal EEG evaluation of mental stress system during emotional and nociceptive stress A82-21784 A82-20335 Cerebral hemispheric activity and automonic The effect of motor activity on the development of nervous function cardiac arrhythmias in experimental emotional H82-17868 stress ELECTBOLISIS A82-21713 Synthesis and degradation of amino acids by Change in the nature of the psychotropic effect on contact glow discharge electrolysis, a possible the emotional reactivity and behavior in stress route for prebiotic formation of bio-organic situations depending on the state of the compounds catecholaminergic systems of the brain A82-20924 A82-21739 BLECIBOLIIBS Adaptogenic effect of mebicar during emotional Orthostatic fluid-electrolyte and endocrine stress, exercise, and hypoxia responses in fainters and nonfainters A82-21780 A82-19492 The effects of emotional activation on the spatial BLBC1BOBAGBETIC FIELDS synchronization of human brain biopotentials Acute experimental emotional stress in rabbits in A82-21785 a modulated electromagnetic field Emotional stress as a factor in cardiovascular A82-20307 disorders Metabolic change in test animals as an indicator A82-21796 of the biological effect of an electromagnetic The dynamics and physiological importance of the field having a frequency of 50 Hz activation of the gamma-aoino-butyric acid A82-21758 system in the brain and cardiac muscle under ELECIBOHAGBEIIC BB4SOBBHBHT pain and emotional stress Beasurement of radio frequency permittivity of A82-21808 biological tissues with an open-ended coaxial BHOTIOHS line. I Emotions, sleep, and health A82-20891 A82-21804 Heasurement of radio frequency permittivity of BBOOCBIBB SBCBETIOHS biological tissues with an open-ended coaxial Orthostatic fluid-electrolyte and endocrine line. II - Experimental results responses in faiuters and nonfainters A82-20892 A82-19492

1-17 BBDOCBIBB SJSIBHS SOBJECT IBDBX

BBDOCEI8E SISIBBS Combined effect of simulated weightlessness and Effect of stationary magnetic field on tie accelerations on energy metabolism enzymes endocrine system H82-17820 H82-17814 Hyocardial protein fractions and enzymatic EIDOSCQPBS activity thereof in experimental rats flowa Biophysical fundamentals and instrumentation for aboard Cosmos-936 biosatellite the endovesical Hd:!AG-laser application H82-17832 tumor therapy Metabolic processis in rat skeletal muscles after [SBB-OA-581-81-0] H82-17843 flight aboard Cosmos-936 EIDOTHBLIOfl H82-17833 The ultrastructure of the liver sinusoids of mice Activity of some enzymes of carbonhydrate under conditions of acute stress - Horphonetric metabolism in rat skeletal muscles after space study flight 482-21782 H82-17834 EIEBSY BBQOIBEHBBTS BBZYHES Characteristics and patterns of tie individual Emergence of flavin catalysis - An approach based development of male and female rats in the light on the concept of bioorganic evolution of the energy rule of skeletal muscles 482-20964 482-21721 On the origin of photosynthetic eukaryotic cells.- EiBBGI TBASSFBB Cyanidinm caldarinm as a 'bridge* alga between Bioenergetic characteristics of various kinds of prokaryotic cyanobacteria and eukaryotic physical loads rhodophytes: Evidence from environmental, A82-20331 polysaccharide biochemistry and nltrastructural EMUHBBATIOI studies A mathematical method for the enumeration of 482-20973 doublet codes in genetic coding theory Characteristics of the relations of the primary A82-20953 responses of the pentose phosphate pathway to EHVIB01HEBI HODBLS glycolysis in the bone marrow of irradiated rats Cyanamide mediated syntheses of leu, ala, and pie A82-21725 peptides under plausible primitive earth Norepinephrine and enzymes of synthesis and conditions degradation thereof in the rat hypothalamus A82-20931 following flight aboard the Cosmos-936 EBTIBOHBEBT SIHOIiTIOl biosatellite Chemical evolution of model systeos of primeval N82-16716 earth periphery and thermal polymerisation of Succinate dehydrogenase and cytochrome oxidase aqueous solutions of cyanides activity in tissues of rats submitted to A82-20933 long-term hypokinesia The cold theory of the origins of life - H82-16723 Assumptions for the theory and experimental Influence of electromagnetic waves in millimeter evidence band on inductoprotein synthesis of A82-20935 penicillinase by staphylococcus aureas Environmental conditions for the formation of H82-17847 oarigranules and kinetic studies on the formation Effect of hypogeomagnetic field on activity of chemical evolution of amino acids in sea some cerebral enzymes medium H82-17853 A82-20912 BBZYHOLO6Y EBZTBE ACTIVITY LOB isoenzyme spectrum in intact and denervated Could the biochemical metabolism be different skeletal muscles of rats of various age during A82-20976 cold adaptation Change in the cytochemical indicators of A82-21798 carbohydrate metabolism in the peripheral blood BPICABDIOS neutrophils of pilots Hucleic acid and protein metabolism in cardiac A82-21U57 muscle The relationship between carbohydrate and lipid 482-21772 metabolisms in muscle cell energetics under the EPILEPSY influence of ATPase loading - flathematical oodel The role of biofeedback in the adaptive regulation A82-21706 of pathological bioelectric brain activity Lysosomes under conditions of stress A82-20328 A82-21770 BPITHBLIOB Effects of diozalim and oxamide on succinate and Dynamics of the condition of granulation tissue lactate dehydrogenase activities in rat liver, after injuries sustained at different times of kidney and brain tissues and on the chromosomal the day apparatus of bone marrow cells A82-21763 A82-21778 The existence of an endogenous biorhythm in The role of nrokinase in the regulation of the chromatin-positive cells of the bnccal fibrinolytic activity of blood under normal epithelium in women conditions A82-21783 A82-21799 EB60METBBS The effects of daily blood sampling on creatine The application of bicycle ergometry to the early phosphokinase, aspartate aminotransferase and detection of ischemic heart disease alanine aminotransferase activities in the blood A82-21775 serum of the monkey EBYTHBOCYTBS A82-21811 Changes of the aggregation and orientation Temperature dependence of alanine and aspartate structure of blood in pulsating flow aoinotransferase activities in rat brain during A82-20333 hypothermia of various durations and adrenalectomy Some indicators of protein metabolism in 182-21812 erythrocytes during radiation sickness and Enzymatic capacities of skeletal muscle - Effects following cystamine injection of different types of training 482-21724 482-22248 The correlation between hematologic and Cathepsiu activity of skeletal muscle and biochemical indicators in the turtles Testudo oyocardla myofibrils after exposure to horsfieldi weightlessness and accelerations 482-21733 H82-16714 Effect of low-temperature on the membrane Borepinepnrine and enzymes of synthesis and permeability of erythrocytes reconstituted in degradation thereof in the rat hypothalamus media of different ionic composition following flight aboard the Cosmos-936 482-21737 biosatellite Erythrocyte indices during a competitive marathon H82-16716 A82-21932

1-18 SUBJECT IBDBZ FLIGHT CBEiS

Cytokinetic evaluation cf erythropoiesis during BYE DISEASES long-tern.orbital flights Detection of amblyopia utilizing generated retinal B82-16715 reflexes Effect of space flights cf different duration on [ HASA-CB-161944] H82-16732 energy metabolism of human erythrocytes BIB HOVBBEBIS B82-17817 Method of recording rotatory eye reflexes Facilitated diffusion of snail non-electrolytes in H82-16727 the .human red blood cell H82-17855 ESCHBBICBIA Genetic damage in Escherichia coli K12 AB2480 by FACE (AHATOHX) broad-spectrun near-ultraviolet radiation Vestibular responses of neurons in the feline 482-22200 anterior suprasylvian gyrus and their ESTEBS interaction with responses to acoustic and Abiotic synthesis of phosphoric esters of facial stimuli monosaccharides according to the 'cold model* A82-20309 A82-20923 The existence of an endogenous biorhythm in ESTIBATES chroaatin-positive cells of the buccal Choosing among alternatives with uncertain epithelium in women outcomes: Effect of prior curing and estimation A82-21783 requirements FAB ULTRAVIOLET BADIATIOI [AD-A106143] H82-16739 Far 0V photolysis of methane-water gaseous EVACUATISG (TfiilSPOBTATIOS) mixtures and the prebiotic synthesis of aldehydes Physical and physiological features of long-range A82-20913 flight and its impact on patients FATIGOB (BIOLOGY) A82-19012 Certain features of cerebral hemodynamics in doing EVOKED BBSPOBSB (CSICBOPBISICIOGT.) mental work at different air temperatures Freguency characteristics of visual evoked A82-21759 potentials in different regions of the human Functional state of the hippocampal-reticular cerebral cortex complex under submaximal physical load and fatigue A82-20314 A82-21786 Coordination of processes in the hierarchic Fatigue in Flight Inspection Field Office (FIFO) structure of the visual analyzer flight crews A82-21788 [AD-A106791] H82-16733 EXCBBTIOB FATTY ACIDS Increased excretion of urea and Nonesterified fatty acid metabolism during H/tau/-methylhistidine iy rats and humans after exercise in humans a bout of exercise A82-21809 A82-21927 A model for essential hypertension: Hetabolic Vitamin C, B sub 1 and B sub 6 excretion in urine studies during 182-day antiorthostatic hypokinesia N82-17867 H82-17824 FBBALES EXBBCISB PHYSIOLOGY. Comparative study of several physiological Erythrocyte indices during a competitive marathon parameters in the evaluation of functional A82-21932 condition in nurses Cardiac output increase and gas exchange at start A82-21826 of exercise FIBBIH A82-21936 Studies on structure and function relationship in Enzymatic capacities of skeletal muscle - Effects fibrinogen of different types of training H82-17859 A82-22248 FIBBISOGBH Comparative antihypoxic efficacy of pressure The role of urokinase in the regulation of the chamber conditioning and fasting of man fibrinolytic activity of blood under normal H82-16729 conditions EXOBIOLOGY A82-21799 OSSB report: Space biology and aerospace Blood fibrinogen as related to immersion in water medicine, volume 15, no. 6, November - December for seven days and short-term space flight 1981 B82-17836 [JPBS-79849] H82-16704 Studies on structure and function relationship in Positions, movements and eguilibrinm of rats after fibrinogen flights aboard biosatellites B82-17859 H82-16713 FIBBOBLAS1S Cathepsin activity of skeletal muscle and Dynamics of the condition of granulation tissue nyocardia myofibrils after exposure to after injuries sustained at different times of weightlessness and accelerations the day H82-16714 A82-21763 EXPIBATIOl FINGBBS A computational model for expiratory flow The economy of muscular work during unfused tetanus A82-21929 A82-21701 EXPIBED AIB The dynamics of muscular relaxation following Breath-by-breath measurement of true alveolar gas unfused tetanuses of different durations exchange A82-21707 A82-19498 FIBST AID The use of oxygen as the test gas in the First aid for thorax traumas: Thorax drainage determination of the closing volume of through suction - Report on 25 cases respiratory ducts A82-19016 A82-21801 FLIGHT BITBAIBBBBSIBIAl EBVIBOBflEBIS Functional characteristics of receptors connected Extreme environments - Are there any limits to life with sustaining the flight of the roach A82-20869 Periplaneta Americana L BXXBAIEBBESTBIAL LIFE A82-21716 Organic analysis of the Antarctic carbonaceous FLIGHT CLOTHIBG chondrites iays and means of maintaining heat balance in A82-20908 pilots and cosmonauts Possible impact of cosnochenistry on terrestrial N82-16706 biology.- Historical introduction FLIGHT CBBBS A82-21987 The reliability of flight personnel during the operation of the Hi-4 helicopter A82-19014

1-19 FLIGHT FAII60B SUBJECT IIOBZ

Effects of relative metabolic rate and heart rate Flight simulation in the current Australian variation on the perfor nance of flight attendants airline scene 482-21680 482-20534 Causes of fatigue anong crews of civil aviation Visual technology and the future for flight helicopters simulators H82-16708 482-20538 Physiological and hygienic evaluation of vibration Antihypoxic efficacy of intermittent mode of in the cockpit of a cargo helicopter pressure chamber conditioning of man H82-16709 N82-17827 Fatigue in Flight Inspection Field Office (FIFO) Development of the Automated Performance flight crevs Assessment and Bemedial Training System [AD-1106791] 1182-16733 (4P4BTS): A landing signal officer training aid FLIGHT FATIGUE [AD-A106224] H82-17873 Causes of fatigue among crevs of civil aviation FLO! DISIBIBOIIOH helicopters Begional distribution of cardiac output in N82-16708 unanesthetized baboons during +Gz stress with Physiological and hygienic evaluation of vibration and without an anti-G suit in the cockpit of a cargo helicopter 482-21681 H82-16709 FLOB 7ISU4LIZATIOH DOT/FAA Human Factors Rorkshop on Aviation. Flow visualization techniques in medical and Transcript, volume 2 biological applications [AD-A107803] U82-17877 482-20778 FLIGHT FITBBSS FLUID FLO! A study of treadmill exercise protocols for 4 hydrodynamic model of an outer hair cell Chinese males [SASA-TH-82773] H82-16743 A82-21677 FLIBI BISSI01S FLIGHT HAZABDS Comets and the origin of life - The stable isotope Effects of long-tern exposure to low levels of approach ozone - A review 482-20864 482-21676 FOOD PBOCESSIB6 FLIGHT SAFBTI Storage stability and improvement of intermediate Flight simulation.- The military need moisture foods, phase 5 A82-20529 [HASA-CB-167503] H82-16742 FLIGHT SIHOLATIOH FOBHALDEHIDB Advanced aviation concepts evaluation through Photoassisted carbon dioxide reduction and computer driven simulation human factors formation of twoand three-carbon compounds consideration in flight training simulator design prebiological photosynthesis 482-19258 A82-20920 Flight simulation in the current Australian FOSSILS airline scene Evolution of the terrestrial atmosphere and its A82-20534 fossils in biosystems Visual technology and the future for flight 482-20960 simulators 482-20538 Acceleration induced voltage variations in the electrocardiogram during exhaustive simulated G4HHA BAIS aerial combat maneuvering The radiolysis and radioracemization of amino 482-21683 acids on silica surfaces FLIGHT SIHOLATOBS 482-20019 Flight simulation - The military need Absence of the additive effect in the combined A82-20529 irradiation of Crepis capillaris seeds and Flight simulation in the current Australian seedlings by gamma rays and neutrons airline scene 482-21723 482-20534 G4S CHBOHATOGBAPHI The semi-automatic instructional system of The radiolysis and radioracemization of amino B-52 weapon system trainers acids on silica surfaces 482-20539 482-20019 A program for assessing pilot mental state in GAS COBPOSITIOH flight simulators The use of oxygen as the test gas in the [4144 PAPEB 82-0257] 482-22078 determination of the closing volume of FLIGHT STBESS (BIOLOGT) respiratory ducts The reliability of flight personnel during the 482-21801 operation of the Hi-4 helicopter GAS DB1SITX A82-19014 Pulmonary gas exchange during altered density gas Change in the cytochemical indicators of breathing carbohydrate metabolism in the peripheral blood 482-21935 neutrophils of pilots GAS EICHAHGB 482-21457 Breath-by-breath measurement of true alveolar gas Effects of relative metabolic rate and heart rate exchange variation oc the performance of flight attendants A82-19498 482-21680 Evaluation of safety of decompression from the Begional distribution cf cardiac output in critical vclnme of gas bubbles formed in the unanesthetized babogjis during +Gz stress with organism and without an anti-G suit A82-21717 482-21681 The effect of blood pressure in the pulmonary 4 program for assessing pilot mental state in artery on gas exchange in functionally flight simulators heterogeneous lungs [4144 P4PEB 82-0257] 482-22078 A82-21738 Effect of transmeridional flights on biorhythm of Pulmonary gas exchange during altered density gas zone formation by Streptomyces levoris breathing 1182-16711 A82-21935 Cardiac output and cardiac cycle phase structure Cardiac output increase and gas exchange at start of pilots during flights of exercise H82-17821 A82-21936 FLIGHT TBAIIIIG Distinctions of regeneration of confined Flight simulation - The ailitary need atmosphere by means of photosynthesis of 482-20529 unicellular algae H82-16720

1-20 SUBJECT IHDBX BBABI DISEASES

GAS PBBSSOHE GLICOLISIS The measurement of oxygen and carbon dioxide Characteristics of the relations of the primary partial pressures in tissues by the gas depot responses of the pentose phosphate pathway to netbod glycolysis in the bone marrow of irradiated rats A82-20318 A82-21725 GAS TEABSPOBT GOALS Oxygen transport in dogs native to high altitudes A systems analysis of human motor reactions in during exercise various nodes of operation of goal-directed A82-21719 behavioral acts 6ASEODS DIFPDSIOH A82-21729 Bate of uptake of carbon aonoxide at different G£A?IBECEHOBS inspired concentrations in hunans In vitro Ca-45/++/ uptake and exchange by A82-21930 otoconial complexes in high and low K/+/Ba/+/ GBLATI1S fluids Storage stability and improvement of intermediate 482-22249 moisture foods, phase 5 GB4?ITATIOBA1 EFFECTS [BASA-CB-167503] 882-16742 Simulation of some of man's movements in different GBHBBAL iflATIOi AIBCBAFT gravity fields The prevalence of visual deficiencies among 1979 882-16712 general aviation accident airnen GBAVITAIIOHAL FIELDS A82-21688 Simulation of some of man's movements in different GEIEXIC CODE gravity fields Origin of translation. - The hypothesis of N82-16712 permanently attached adaptors proposed GBOOHD BASED COBIBOl prebiotic amino acid synthesis Human-machine interface issues in the A82-20022 Hultisatellite Operations Control Center-1 A theory of the origin of life (MSOCC-1) A82-20023 [SASA-TM-83826] 882-17875 A mathematical method for the enumeration of GBOiTB doublet codes in genetic coding theory Characteristics and patterns of the individual A82-20953 development of sale and female rats in the light Origin and evolution of the genetic code of the energy rule of skeletal muscles A82-20955 A82-21721 The origin and evolution of the genetic code GOABOSIIES A82-20956 Template-directed synthesis of qligoguanylic acids Evolutionary processes of the genetic code - Metal ion catalysis 482-20957 482-20933 Summary of evidence for an anticodonic basis for the origin of the genetic code A82-20958 H Evolution of the terrestrial atmosphere and its HABIIA1S fossils in biosystems Introduction prognosis and its methodological A82-20960 aspects -•— plant growth in new habitats Emergence of flavin catalysis - An approach based A82-21722 on the concept of bioorganic evolution BAIB 482-20961 A hydrodynamic model of an outer hair cell GEIEIICS [BASA-TM-82773] H82-16743 Genetic damage in Escherichia coli K12 AB2480 by BALOPHILES broad-spectrum Dear-ultraviolet radiation DBA-protein complex from an extreme halophile - A A82-22200 histone-like protein in archaebacteria Possible mechanism for cheiical induction of 482-20970 chromosome aberrations in male aeiotic and BAZABDS postmeiotic germ cells of mice Methods for diagnosing hearing loss in workers [DE81-031999] H82-16700 exposed to high noise levels in accordance with Cytologic and biochemical genetic effects of state standards chemical carcinogens A82-21793 [AD-A107615] 882-17864 HEAD (ABATOHY) GBOHA6BBTISH Evaluation of man's endurance of local pressure to Mortality in acute uyocardial infarction as the head and objective assessment of hygienic function of geomagnetic field activity in Yerevan specifications for protective helmets 882-17852 882-16710 Effect of hypogeomagnetic field on activity of HEALTH some cerebral enzymes Emotions, sleep, and health B82-17853 A82-21804 6LO1 DISCHARGES Physical health of truck drivers in the open-pit Synthesis and degradation of amino acids by mining industry of the far north contact glow discharge electrolysis, a possible A82-21805 route for prebiotic formation of bio-organic BEALIH EHISICS compounds Mechanisms of cadmium absorption in rats A82-20924 [PB82-108184] 882-16703 GLDCOSIDES Clinical distinctions of radiation sickness with The influence of some triterpenic glycosides on exposure of different parts of the human body to C-14-alanine inclusion into the bone-marrow radiation cells of rats 882-16726 A82-20306 HBABIBG GLICIIE Characteristics of the structure and functions of Histidyl-histidine catalysis of glycine the middle ear of lizards condensation in fluctuating clay environments A82-21823 A82-20952 HEABI DISEASES GLICOGEIS A study of treadmill exercise protocols for Glycogeu and nonspecific adaptation to cold Chinese males A82-19494 A82-21677 Change in the cytochemical indicators of Investigation and evaluation of cardiac carbohydrate metabolism in the peripheral blood arrhythmias in healthy young persons neutrophils of pilots A82-21710 A 82-21457 The effect of motor activity on the development of cardiac arrhythmias in experimental emotional stress A82-21713

1-21 HEABT F01CTIOB SOBJECT IIDBX

Effect of coding of the rhythmo-inotropic ratio HEHODIHABIC EESPOISES in a pathological!; altered myocardium Changes of the aggregation and orientation 482-21740 structure of blood in pulsating flow Mechanisms of compensation and adaptation in 482-20333 relation to the hyperinflation of the heart Changes in the main characteristics of the central 182-21756 henodynamics of healthy individuals and The application of bicycle ergometry to the early hypertension patients during physical exercise detection of ischemic heart disease 482-21711 A82-21775 Mechanisms of compensation and adaptation in Emotional stress as a factor in cardiovascular relation to the hyperfunction of the heart disorders A82-21756 482-21796 A comparative evaluation of the heoodynamic Seasonal rhythm of the immune reactivity and heart effects of large doses of morphine, dipidolor, tolerance to physical load in patients vith pentazocine, and phentanyl ischemic heart disease A82-21795 482-21802 Computer-aided analysis of the effect of the Evaluation of the functional state of the initial narcosis on the central hemodynaoics cardiovascular systen in patients uith ischenic A82-21797 heart disease with reference to the nature of Question of redistribution of blood in orthostatic their occupational activity position 482-21803 H82-16705 HEABT FOBC1IOB Systemic and cerebral hemodynamics in flight Mechanisms of compensation and adaptation in personnel exposed to moderate hypoxia relation to the hyperfunction of the heart H82-16707 482-21756 Besults of study of hemodynamics and phase The relationship between cardiac and motor structure of the cardiac cycle during functional components of a conditioned reflex upon the test with lower body negative pressure during local cooling of various zones of the cerebral 140-day Salyut-6 station flight cortex in cats H82-16722 482-21787 Jugular, right atrial pressure and cerebral Cardiac output increase and gas exchange at start hemodynamics of healthy man submitted to of exercise postural tests 482-21936 H82-17825 BEAUX BATE HEHODIHABICS Pulse rate evaluation.of the relative Pulmonary shunting and its regulation physiological intensity of aerobic muscular work 482-21728 482-20331 Echoencephalographic indices in patients with Effects of relative metabolic rate and heart rate hypertensive disease under the effect of variation on the perfcraance of flight attendants functional loads 482-21680 482-21753 The dynamics of heart rate recovery following vork Phasic energy analysis of rheoencephalograms in of various aerobic intensities the detection of the decompensation of cerebral 482-21815 hemodynamics Fatigue in Flight Inspection Field Office (FIFO) 482-21754 flight ereus Certain features of cerebral hemodynamics in doing [AD-4106791] H82-16733 mental work at different air temperatures HEAI ACCUBATIZAIIOH 482-21759 Mechanisms of adaptation to ergothernic hypoxemia Effects of pyrroxane and methylapogalantamine on in athletes specializing in different sports cerebral blood circulation and oxygen regime A82-21820 482-21776 Physical performance tasks required of 0. s. Age related distinctions of cosmonauts regional Marines operating in a desert environment hemodynamics [AD-A107866] N82-17863 H82-17829 HEAT STBQEE HEHOGLOBIi Cardiovascular origins of heatstroke Variability of oxygen affinity of blood - Human pathophysiology - An anesthetized rat model subjects native to high altutnde 482-21687 A82-19493 BELICOPTBB PEBFOBBAHCE The correlation between hematologic and The reliability of flight personnel during the biochemical indicators in the turtles Testudo operation of the Mi-4 helicopter horsfieldi 482-190H* 482-21733 HELICOPIBBS Effect of low-temperature on the membrane Causes of fatigue among crews of civil aviation permeability of erythrocytes reconstituted in helicopters media of different ionic composition 082-16708 482-21737 Physiological and hygienic evaluation of vibration BEBEDIII in the cockpit of a cargo helicopter Possible mechanism for chemical induction of M82-16709 chromosome aberrations in male meiotic and An evaluation of helicopter noise and vibration postmeiotic germ cells of mice ride qualities criteria [DE81-031999] H82-16700 £NASA-TM-83251] H82-17871 BBTEBOCIC1IC COHPOOHDS HE1HBIS Hitrogen compounds in carbonaceous meteorites - 4 Evaluation of man's endurance of local pressure to reassessment the head and objective assessment of hygienic A82-20909 specifications for protective helmets HBIOKIBASB H82-16710 Some indicators of carbohydrate metabolism in rat HBHAIOLOGI lung during repeated and chronic hypoxia Changes in morphological and cytogenetic A82-20302 hematopoietic indicators in hamadryas baboons BIBEBBATIOB exposed to chronic low-level radiation Effects of temperature on the duration of arousal 482-21726 episodes dnriag hibernation The correlation between hematologic and A82-21934 biochemical indicators in the turtles Testudo HIGH ALTITODE BBBATHIHG horsfieldi Oxygen transport in dogs native to high altitudes 482-21733 during exercise Blood serum nnclease activity in healthy persons 482-21719 and patients with various hematological diseases 482-21813

1-22 SUBJECT IBDBI HOB4B PBBFOBB4BCB

HIGH ALTITUDE BBVIBOHHEBIS HOBAB BODI Variability of oxygen affinity of blood - Hunan Difference between eye closure and visual subjects native to high altotude stabilization in the control of posture in man 482-19493 482-21686 Adaptation to high-altitude hypoxia at different The economy of muscular work during unfnsed tetanus ambient temperatures /before and daring 482-21701 adaptation/ Oecussations in the human muscular system A82-21715 482-21762 HIGH 41IITODB TESTS Clinical distinctions of radiation sickness with Psychological testing at high altitudes exposure of different parts of the human body to 482-21679 radiation HIGH PBESSOBB H82-16726 Evaluation of safety of decompression from the Chemicals Identified in Human Biological fledia critical volume of gas bubbles formed in the [DE81-030813] B82-16735 organism HOHAI FACIOBS EHGIBEEBIBS A82-21717 Psychological problems in the mutual adaptation of HIGH TEBPBBATOBB EHflBOBHEIXS man and machine in control systems Russian The effects of elevated environmental temperature book combined uith radiation on the organism 482-19000 482-21752 Evaluation of maximal and snbmaximal static muscle HIPPOCAMPUS exertions Functional state of the hippocamtal-reticnlar 482-19223 complex under submaximal physical load and fatigue Control and automatic processing during tasks 482-21786 requiring sustained attention - 4 new approach HISTIDIIB to vigilance Histidyl-histidine catalysis of glycine 482-19225 condensation in fluctuating clay environments Advanced aviation concepts evaluation through A82-20952 computer driven simulation human factors Increased excretion of area and consideration in flight training simulator design N/tau/-methylhistidine by rats and humans after 482-19258 a bout of exercise Survival in space spacesuit development 482-21927 482-20257 HISTOCHEHICAL AIALISIS A program for assessing pilot mental state in 4 histochemical investigation of the microvascular flight simulators effectors regulating the supply of blood to the [4IA4 P4PEB 82-0257] 482-22078 cerebral cortex Evaluation of man's endurance of local pressure to A82-21744 the head and objective assessment of hygienic HOBEOSTiSIS specifications for protective helmets An investigation of the biological activity of B82-16710 chalones separated from normal livers and from Pilot workload: A survey of operational problems livers that are being regenerated [AD-4107758] H82-16745 482-21742 Human-machine interface issues in the The multiple forms of tyrosine aminotransferase in Hultisatellite Operations Control Center-1 rat liver cells and their role in cellular (BSOCC-1) homeostasis [B4S4-TH-83826] H82-17875 482-21807 DOT/F44 Human Factors Workshop on Aviation. Enzymatic capacities of skeletal muscle - Effects Transcript, vpl 1 of different types of training [AD-A107802] N82-17876 482-22248 OOT/FAA Human Factors Workshop on Aviation. Hays and means of maintaining heat balance in Transcript, volume 2 pilots and cosmonauts IAD-4107803] N82-17877 H82-16706 HOB4H P4THOIOGI BOHIBG The healthy and the diseased human brain Study of homing pigeons in Brazil: £ome Bussian book preliminary results 482-18872 [IBPE-2248-PHE/032] N82-17839 Changes in microcirculatory flow with respiratory HOBHOBE BBTABOLISHS insufficiency The effect of the prolonged administration of 482-20323 sodium hydroxybutyrate on the physical vork The role of biofeedback in the adaptive regulation capacity and muscle tissue state of rats of pathological bioelectric brain activity A82-21779 482-20328 The multiple forms of tyrosine aminotransferase in Investigation and evaluation of cardiac rat liver cells and their role in cellular arrhythmias in healthy young persons homeostasis 482-21710 482-21807 Effect of cooling of the rhythmo-inotropic ratio HOBH01ES in a pathologically altered myocardium Effects of vasopressin administration on diuresis 482-21740 of Hater immersion in normal humans Summary of a discussion on the problem of the A82-19491 'biological norm1 /in relation to an assessment Bechanisms for the regulation of the intracellular of criteria of the harmfolness of chemical calcium distribution effects/ A82-21774 482-21750 HDBAB BBBAVIOB Clinical results on thymectomy in patients with Emotions, sleep, and health myopathy in relation to the degree of muscular 482-21804 weakness HUHAI BEIBGS 482-21755 Functional condition and work capacity under Hygienic standards for industrial noise mountain conditions 482-21794 482-20313 Blood serum nuclease activity in healthy persons Frequency characteristics of visual evoked and patients with various hematological diseases potentials in different regions of the human A82-21813 cerebral cortex Trial on the use of stabilography in the medical 482-20314 supervision of boxers The effects of an agueous potassium loading test 482-21817 on kidney function HOBAB PEBFOBBABCB 482-20329 Differences in eye movement data recorded by Human auditory brainstem electric responses to electro-oculography and corneal reflection binaural and monaural stimuli techniques B82-17861 482-19224

1-23 HOHAH BE4CTIOHS SUBJECT IHOBZ

Control and automatic processing daring tasks BIDBOCIAHIC AGIO requiring sustained attention - A new approach Clay-mediated reactions of HCH oligomers - The to vigilance effect of the oxidation state of the clay 482-19225 A82-20917 Effects of relative metabolic rate and heart rate HCH oligomerization - Isolation and preliminary variation on the perforaance of flight attendants characterization of a new precursor of adenine £82-21680 A82-20930 Changes in the main characteristics of the central HIDBODIMAHICS hemodynamics of health; individuals and A hydrodynamic model of an outer hair cell hypertension patients during physical exercise [BASA-TH-82773] H82-16743 482-21711 HIDHOGEi The effects of elevated environmental temperature Formation of prebiotic precursors from model combined with radiation on the organism reducing atmospheres Bole1 of hydrogen escape 482-21752 A82-20911 The physical activity of humans as a social and HYGIEBE biological problem Complex physiological-hygienic characteristics of 482-21760 a new work-rest regime for seamen The effects of emotional activation on the spatial A82-21748 synchronization of human brain biopotentials Summary of a discussion on the problem of the 482-21785 'biological norm* /in relation to an assessment 4 study of tropomyosins in human muscular and of criteria of the harmfainess of chemical nonmuscular organs effects/ 482-21806 A82-21750 Predicting the potentials of young swimmers based Physiological and hygienic evaluation of vibration on clinical and physiclcgical data in the cockpit of a cargo helicopter 482-2181H 1182-16709 ' Comparative antihypoxic efficacy of pressure Evaluation of man's endurance of local pressure to chamber conditioning and fasting of man the head and objective assessment of hygienic H82-16729 specifications for protective helmets An analysis of cognitive mapping skill H82-16710 I4D-4106145] H82-16740 Hygienic principles of ongoing monitoring of Ability differences and cognitive mapping skill quality of recycled water during space flights f4D-4106389] H82-16741 H82-16717 Pilot workload: 4 survey of operational problems Toxicological and hygienic aspects of improving [AD-A107758] H82-16745 additional purification of water reclaimed from Physical performance tasks regnired of 0. S. urine Marines operating in a desert environment H82-16718 [AD-A107866] H82-17863 HIPEBBABIC CHAHBEBS HO 114 H BEACTIOBS Brain monoamine oxidase activity during cold Electroencephalographic correlates of the adaptation and under the combined effects of differentiation between verbal stiiuli during cold and hyperbaric oxygenation natural night sleep in humans A82-19746 482-20315 HIPEBCAPBIA The effects of narcotic analgesics on animal The role of extracellular 02 and C02 tensions in sensitivity to hypoxia membrane mechanisms of cerebral arterial smooth 482-20316 muscle regulation 4 systems analysis of human motor reactions in 482-19747 various modes of operation of goal-directed The significance of airflow resistance to changes behavioral acts in responses to increasing hypercapnia 482-21729 482-20327 The thermal response of a human in tie near-zone HYPEBKIHESIA of a resonant thin-wire antenna The effect of the motor activity regime on the 482-22206 development, conservation, and regeneration of Phenomena of fluctuation of human reaction to defensive conditioned reflexes in rats antiorthostatic position 482-20305 H82-16721 HIPBBISSSIOB Human reactions to elf electric and magnetic The possibility of using mathematical methods for fields: An annotated bibliography of current predicting the results of the surgical treatment literature of patients with vasorenal hypertension [PB 82-102567] B82-16737 A82-21709 HOB41 TOLEBAHCES Changes in the main characteristics of the central Natural resistance of the organisms of seamen hemodynamics of healthy individuals and during postcruise rest hypertension patients during physical exercise 482-20311 A82-21711 Hicrocirculation, tolerance to physical strain, The role of natriuresis in the prophylactic effect and certain homeostasis parameters in patients of adaptation to hypoxia in the case of with angina pectoris hereditary hypertension 482-20324 A82-21712 Evaluation of safety of decompression from the Echoencephalographic indices in patients with critical volume of gas bubbles fomed in the hypertensive disease under the effect of organism functional loads 482-21717 A82-21753 Seasonal rhythm of the immune reactivity and heart Emotional stress as a factor in cardiovascular tolerance to physical load in patients with disorders ischemic heart disease A82-21796 482-21802 A model for essential hypertension: Metabolic Evaluation of man's endurance of local pressure to studies the head and objective assessment of hygienic N82-17867 specifications for protective helmets HIPBBTBBBHIA 1182-16710 The effect of synaptically active drugs on the HOHAB WASTES hyperthermic effect of prostaglandin E2 in rats Possible use of house fly larvae for utilization A82-21741 at organic waste in biological life-support The effects pf successive ionizing radiation and systems heat on antibody formation M82-16719 A82-21751 HIDBOCABBOBS BIPODISAHIA Formation of prebiotic precursors from model Combined effect of simulated weightlessness and reducing atmospheres Bcle of hydrogen escape accelerations on energy metabolism enzymes 482-20911 H82-17820

1-24 SUBJECT IBDBI IBPACT DAH1GE

Betabolic process!£ in rat skeletal muscles after Special and clinical physiology of hypoxic states flight aboard Cosmos-936 482-20317 B82-17833 Elevation of hypoxia resistance with the use of Activity of soBe enzjnes cf carbonhydrate gatimine metabolism in rat skeletal nuscles after space 482-20319 flight The influence of adaptation on the periodic effect H82-17834 of hypoxia on the poststress activation of the BIEOKIHBSIA primary immune response The effect of the notor activity regime on the 482-20320 development, conservation, and regeneration of 4 combined method for the study of tissue defensive conditioned reflexes in rats respiration under conditions corresponding to 482-20305 natural gas homeostasis The morphology of the lungs of dogs whose movement 482-20321 is completely restricted Psychological testing at high altitudes A82-21765 482-21679 age Borphofunctional characteristics of chromaffin The role of natrinresis in the prophylactic effect tissue in the celiac nodes, both in the norm and of adaptation to hypoxia in the case of vith hypokinesia hereditary hypertension A82-21766 482-21712 nationalizing physical regimen of sedentary workers Adaptation to high-altitude hypoxia at different A82-21818 ambient temperatures /before and during Succinate dehydrogenase and cytochrone ozidase adaptation/ activity in tissues of rats submitted to 482-21715 long-term hypokinesia The effect of piracetam on the body's resistance H82-16723 to hypoxia Human lipid metabolism daring confinement in 482-21777 pressure chamber 4daptogenic effect of mebicar during emotional H82-17822 stress, exercise, and hypoxia Vitamin C, B sub 1 and B sub 6 excretion in urine 482-21780 during 182-day antiorthostatic hypokinesia Systemic and cerebral hemodynamics in flight H82-17824 personnel exposed to moderate hypoxia HIPOTHAJ.AHUS N82-16707 Acute- experimental emotional stress in rabbits in lipid spectrum of the myocardium of white rats a nodulated electromagnetic field exposed to hypoxic hypoxia 482-20307 H82-16724 Horepinephrine and enzymes of synthesis and Comparative antihypoxic efficacy of pressure f degradation thereof in the rat hypothalamus chamber conditioning and fasting of man following flight aboard the Cosmos-936 H82-16729 biosatellite Antihypoxic efficacy of intermittent mode of H82-16716 pressure chamber conditioning of man HIPOTBEMIA H82-17827 Effect of cooling of the rhythmo-inotropic ratio Method of assessing individual resistance of rats in a pathologically altered myocardium to hypoxic hypoxia 482-21740 H82-17837 The effect of cholinomimetics on the development of hypothermia A82-21781 The relationship between cardiac and motor IHAGE COBXBASX components of a conditioned reflex upon the Flow visualization technigues in medical and local cooling of various zones of the cerebral biological applications cortex in cats A82-20778 A82-21787 IHAGIHG IECHHIQOBS Temperature dependence of alanine and aspartate Visual technology and the future for flight aminotransferase activities in rat brain during simulators hypothermia of various durations and adrenalectomy A82-20538 A82-21812 IHBOBILIZATIOH HIPOVCLBBIA Succinate dehydrogenase and cytochrome oxidase Effect of blood volume on sweating rate and body activity in tissues of rats submitted to fluids in exercising humans long-term hypokinesia A82-19195 H82-16723 HIPOXEH1A IBBOHITY Bechanisms of adaptation to ergothermic hypoxemia The influence of adaptation on the periodic effect in athletes specializing in different sports of hypoxia on the poststress activation of the A82-21820 primary immune response HIEOXIA A82-20320 Enhanced heat production in physically restrained Stress and immunity in athletes rats in hypoxia A82-21821 482-19496 IHBOBOLOGI Alterations in responses to drugs of atria from Natural resistance of the organisms of seamen white rats acclimated to hypobaric hypoxia during postcruise rest 482-19497 A82-20311 The role of extracellular C2 and C02 tensions in Cellular and molecular bases of local immunity membrane mechanisms of cerebral arterial smooth A82-21773 muscle regulation Seasonal rhythm of the immune reactivity and heart 482-19747 tolerance to physical load in patients with Some indicators of carbohydrate metabolism in rat ischemic heart disease lung during repeated and chronic hypoxia A82-21802 A82-20302 A study of tropooyosins in human muscular and Physiology and pathology of respiration and means nonmuscular organs of correcting oxygen deficiencies in an organism 482-21806 /Meeting of the Interdepartmental Commission on The mathematics of immunity response to viral the Coordination of Studies in Medicine of the intrusion Academy of Sciences of the Ukrainian SSB and the 482-21824 Ministry of Health of the Ukrainian SSB/ IBPACT DABAGE A82-20303 Trial on the use of stabilography in the medical The effects of narcotic analgesics on animal supervision of boxers sensitivity to hypoxia A82-21817 482-20316

1-25 IttPLilTBD ELECTBODBS (BI010GI) SDBJECT IHDKX

Beview of literature and regulation relating to IOB EICHAIGB BBSIBS thoracic impact tolerance and in jar; criteria The polymerization products of [PB82-108697] H82-16736 alpha-aainopropionitrile - The component IHPLABTBD BLECTEODES (BI0106I) separation using cation-exchange resin Waveguide technigue for the calibration of A82-20930 miniature implantable electric-field probes for IOB EXCHABGIIG use in microwave-bioeff€Cts studies Soae mechanisms of calcium transport by the 482-20893 cardiac sarcolemma IS-FLIGHT BOBITOBIHG B82-17810 Cardiac output and cardiac cycle phase structure IOBIZIH6 BADIATIOi of pilots during flights The biological effects of low-level ionizing H82-17821 radiation IBDOSIBIAL SAFETY 482-20116 Hethods for diagnosing hearing loss in workers The effects of successive ionizing radiation and exposed to high noise levels in accordance with heat on antibody formation state standards A82-21751 A82-21793 IBOB COEFOOIDS Hygienic standards for industrial noise Clay-nediated reactions of BCD oligomers - The A82-2179U effect of the oxidation state of the clay IBFOBHATIOH FLO! A82-20917 Control and automatic processing during tasks IBOB HEIEOBIfBS requiring sustained attention - A nev approach Abiotic organic synthesis in space to vigilance A82-20910 A82-19225 IBBAOIATIOB IHFBABED SPBCTBA Asymmetrical radical formation in beta-irradiated Organic and inorganic interpretations of the D- and L-alanines Martian DV-IB reflectance spectrum A82-209U9 A82-21208 Biophysical fundamentals and instrumentation for IBBIBITOBS the endovesical Bd:YAG-laser application A mathematical model of cell populations vith stem tuner therapy cells [HBB-DA-581-81-0] N82-178U3 A82-21702 IBBEVBBSIBLE PBOCBSSBS Approaches to the removal of G2-chalone from the Competition, coexistence and irreversibiiity in liver of rats models of early molecular evolution A82-21810 A82-20951 I1JDBJBS IBBIIAIIOB Dynamics of .the condition of granulation tissue Mammalian toxicological evaluation of DIHP and after injuries sustained at different tines of DCPD (Phase 3 - IflPA) the day [AD-A10757U] H82-17840 A82-21763 ISCBEBIA IBOBGAHIC COHPOOHDS Hicrocirculation, tolerance to physical strain, Organic and inorganic interpretations of the and certain homeostasis parameters in patients Martian DV-IE reflectance spectrum vith angina pectoris A82-21208 482-2032U IBIBBBOLBCUIAB FOBCBS Mechanisms of compensation and adaptation in Evolving nucleotide binding surfaces relation to the hyperfunction of the heart A82-2095U A82-21756 IBTBBSTEU.AB CHEHISTBI The application of bicycle ergometry to the early Chemical evolution of interstellar dust - A source detection of ischemic heart disease of prebiotic material A82-21775 A82-20863 Seasonal rhythm of the immune reactivity and heart Nature and origin of organic molecules in comets tolerance to physical load in patients with 682-20906 ischemic heart disease IMIEBSTBU.AB EZIIBCTIOH A82-21802 Comets - A vehicle for panspermia Evaluation of the functional state of the 482-20868 cardiovascular system in patients with ischemic IBTEBSTEUAB HATTEB heart disease with reference to the nature of Chemical evolution of interstellar dust - A source their occupational activity of prebiotic material A82-21803 482-2C863 Lipid spectrum of the myocardium of white rats Cooetary material and the origins of life on earth exposed to hypoxic hypoxia A82-20867 B82-1672H Interstellar molecules and the origin of life ISOHBHS A82-20902 A model for the enantiooeric enrichment of On the origin of organic molecules in interstellar polypeptides on the primitive earth space and some of its consequences A82-20020 482-20901 Search for effect of longitudinally polarized Hatare and origin of organic molecules in comets protons on optically active amino acids A82-20906 482-20021 IBIBSHMS Stereoselective interactions of small biological The oyeuteric plexus - Basic principles of nolecules modeling nenronal organization 482-20915 A82-20337 Possible selective adsorption of enantiomers by The role of intestinal nerves in the nutrient Ha-Bontmorillonite induced intestinal hypereoia 482-20916 082-17869 IODISE CQHPOUBDS Comparative evaluation of antimicrobial activity of some urine preservatives JODGHBHTS H82-17830 Choosing among alternatives with uncertain IOB BICHAHGB BEBBBAHE B1BCIBC1IIBS outcomes: Effect of prior curing and estimation in vitro Ca-45/+V uptake and exchange by requirements otoconial complexes in high and Ion K/+/Ha/+/ [AD-A106143] B82-16739 fluids JUPITBB AISOSPHEBB A82-22249 Photolysis of CH4-HH3 mixtures and PH3 as models for the photochemical transformations on the primitive earth and Jupiter A82-2091*

1-26 SUBJECT IHDBI LOB6 DUBATIOI SPACE FLIGHT

Activation of the metabolism of the gamma-aminobutyric acid system in the cerebral K hemispheres under various types of stress KEB06BB A82-21746 Organic geochemistry of the Isua snpracrastals The effect of physical training on the lipid and A82-20961 lipoprotein metabolism in people of various ages KIDBBIS 482-21757 The effects of an aqueous potassian loading test Nonesterified fatty acid metabolism during on kidney function exercise in humans A82-20329 482-21809 The possibility of using mathematical methods for Lipid spectrum of the myocardium of white rats predicting the results cf the surgical treatment exposed to hypoxic hypoxia of patients uith vasorenal hypertension N82-16724 482-21709 Hunan lipid metabolism during confinement in A three-dimensional model for the arrangement of pressure chamber the vascular and tabular components of the renal N82-17822 osnoregulatory apparatus A model for essential hypertension: Metabolic 482-21745 studies Effects of dioxalim and oxamide on succinate and H82-17867 lactate dehydrogenase activities in rat liver, LIPIDS kidney and brain tissues and on the chromosomal Hembrane lipids and the origin of life apparatus of bone marrow cells 482-20943 A82-21778 Peroxidation of lipids in the liver and lungs of KliBTICS rats during prolonged adaptation to the cold Cytokinetic evaluation of erythropoiesis during 482-21736 long-term orbital flights Lipid spectrum of the myocardium of white rats H82-16715 exposed to hypoxic hypoxia H82-16724 LIPOPBOTBIBS The effect of physical training on the lipid and lABIAB lipoprotein metabolism in people of various ages Possible use of house fly larvae for utilization 482-21757 of organic waste in biological life-supRort LIQUID CHfiOHATOGBAPBT systems Resolution of underivatized anino acids by high H82-16719 pressure lignid chromatography, using chiral LASBB APPLICATIONS eluauts Biophysical fundamentals and instrumentation for A82-20944 the endovesical 8d:IAG-laser application LIQUID PHASES tumor therapy Liquid water on a planet over cosmic periods [HBB-04-581-81-0] N82-17843 A82-20907 LEOCIIB LI7BB The radiolysis and radioracemization of amino The effect of cold stress on the level and acids on silica surfaces activity of microsomal cytochrome P-450 in the 482-20019 rat liver LEUKOCYTES A82-21732 Hataral resistance of the organisms of seamen Activation of succinate dehydrogenation in rat during postcruise rest liver by noradrenalin, cAHP and acute cooling 482-20311 482-21731 LIFE SOPPOSI SISTEHS Peroxidation of lipids in the liver and lungs of Survival in space spacesuit development rats during prolonged adaptation to the cold 482-20257 A82-21736 DSSB report: Space biology and aerospace An investigation of the biological activity of medicine, volume 15, no. 6, Hovember - December chalones separated from normal livers and from 1981 livers that are being regenerated [JPBS-79849] S82-1670U 482-21742 lexicological and hygienic aspects of improving Effects of dioxalim and oxamide on snccinate and additional purification of water reclaimed from lactate dehydrogenase activities in rat liver, urine kidney and brain tissues and on the chromosomal H82-16718 apparatus of bone marrow cells Possible use of house fly larvae for utilization 482-21778 of organic waste in biological life-support The ultrastructnre of the liver sinusoids of mice, systems under conditions of acute stress - aorphometric H82-16719 study Distinctions of regeneration of confined A82T-21782 atmosphere by means of photosynthesis of The multiple forms of tyrosine aminotransferase in unicellular algae rat liver cells and their role in cellular H82-16720 homeostasis LIGHT {VISIBLE BADIATIOB) A82-21807 Bhodopsin aggregation under the damaging effects Approaches to the removal of G2-chalone from the of light on the photcreceptbr membranes liver of rats A82-21705 A82-21810 LIGBTIIBG LOHG DOBATIOB SPACE FLIGHT Bates of fixation by lightning of carbon and Cytokinetic evaluation of erythropoiesis during nitrogen in possible primitive atmospheres long-term .orbital flights 882-20016 N82-16715 LIHBS (ABATOBT) Besults ,of study of hemodynamics and phase Disturbances in biological rhythms as a result of structure of the cardiac cycle during functional a conflict of incompatible stimuli test with lover body negative pressure during A82-21720 140-day Salyut-6 station flight LIPID HBTABOLISH N82-16722 Ehodopsin aggregation under the damaging effects Diet of crews of three main expeditions aboard of light on the photoreceptor membranes Salyut-6 orbital station 482-21705 N82-17815 The relationship between carbohydrate and lipid Effect of space flights of different duration on metabolisms in muscle cell energetics under the energy metabolism of human erythrocytes influence of ATPase loading.- Mathematical model H82-17817 482-21706 Prevention of staphylococcal infections during space flights H82-17818

1-27 LORG IBM EFFECTS SOBJECI IBDBI

Human adrenosympathetic system daring immersion in LISOZYHB Hater Lysosoaes under conditions of stress H82-17819 482-21770 LOIG IEBH EFFECTS The influence of muscular vork on the vestigial effects of ccld acclimation M A82-19749 H468EIIC BIPBCTS Effects of long-term exposure to Ion levels of Stationary magnetic fields and reticular ozone - A review influences on adrecergic and chblinergic systems A82-21676 H82-16725 Eeroxidation of lipids in the liver and lungs of H4GBE5IC FIELDS rats during prolonged adaptation to the cold Stationary magnetic fields and reticular 482-21736 influences on adrenergic and cholinergic systems Amino acid metabolism during prolonged intake of H82-16725 dehydrated foods and simulation of some space Human reactions to elf electric and magnetic flight factors fields: An annotated bibliography of current S82-17816 literature LOODBBSS [PB82-102567] H82-16737 Temporal integration of acoustic power for Effect of stationary magnetic field on the interrupted stimuli at snprathreshold levels endocrine system H82-17856 H82-17814 LOB TBHPBB4TOBB BALES The effect of cold stress on the level and 4 study of treadmill exercise protocols for activity of oicrosonal cjtochrome P-450 in the Chinese males rat liver 482-21677 482-21732 Phenomena of fluctuation of human reaction to Effect of low-temperature on the membrane . antiortbostatic position permeability of erythrocytes reconstituted in H82-16721 media of different ionic composition HAHHALS 482-21737 flammalian toxicological evaluation of DIHP and LOB TEHPEB4TOBE BBVIBOBBEBTS OCPO (Phase 3 - IdPA) Activation of succinate dehydrogenation in rat [AD-A107574] 882-17840 liver by noradrenalin, cAUP and acute cooling US HACHIBB SISTBHS 182-21734 Psychological problems in the mutual adaptation of The effect of low temperature on the activity and man and machine in control systems Bussian substrate specificity of monoamine oxidases in book rat brain mitochondria A82-19000 482-21735 Advanced aviation concepts evaluation through Comparative neurophysiclogical characteristics of computer driven simulation human factors cold and caudate tremors consideration in flight training simulator design 482-21790 A82-19258 LOIEB BOOX BEGAIIVB PBESSOHB Hunan-machine interface issues in the Besults of study of hemodynamics and phase Hultisatellite Operations Control Center-1 structure of the cardiac cycle during functional (HSOCC-1) test Kith lower body negative pressure during IHASA-TB-83826] H82-17875 140-day Salyut-6 station flight HAPPIHG S82-16722 An analysis of cognitive mapping skill LOHG HOBPHOLOG7. [AD-4106145] N82-16740 The effect of blood pressure in the pulmonary Ability differences and cognitive mapping skill artery on gas exchange in functionally [4D-4106389] H82-16741 heterogeneous lungs HABIBE CHEHISTBI 482-21738 Chemical evolution and plate tectonics The morphology of the lungs of dogs whose movement 482-20918 is completely restricted HABIHE Ei»IBOHBBHTS 482-21765 The Strecker synthesis in the primitive ocean The use of oxygen as the test gas in the chemical evolution determination of the closing volume of 482-20919 respiratory ducts Helanoidin polymers as possible oxygen sinks in 482-21801 the pre-biotic oceans An asymmetrical model of the airways of the dog lung 482-20921 482-21926 Environmental conditions for the formation of LONGS marigranules and kinetic studies on the formation Some indicators of carbohydrate metabolism in rat chemical evolution of aaino acids in sea lung during repeated and chronic hypoxia medium 482-20302 482-20942 Changes in microcirculatory flow with respiratory A statistical examination of three approaches for insufficiency predicting motion sickness incidence 482-20323 A82-21685 Peroxidation of lipids in the liver and lungs of UBS SURFACE SAHP1BS rats during prolonged adaptation to the cold Organic and inorganic interpretations of the 482-21736 Martian DV-IB reflectance spectrum 4 computational model for expiratory flow A82-21208 482-21929 HASKIBG Bate of uptake of carbon monoxide at different Forward masking of auditory nerve (H sab 1) and inspired concentrations in humans brainstem responses (Bave V) in humans 482-21930 H82-17860 Comparative biochemistry and metabolism. Part 2: HATBBIAL ABSOBPIIOH naphthalene lung toxicity Hechanisms of cadmium absorption in rats £40-4107673] H82-17842 [PB82-1C8184] B82-16703 LIHPH BAIHBH4IICAL HODEIS Changes in the structure and cellular composition The mathematics of immunity response to viral of the inguinal lymph nodes of white rats intrusion subjected to static and dynamic stresses A82-21824 482-21761 A computational model for expiratory flow LTHPHOCITES A82-21929 The influence of adaptation on the periodic effect BBDICAL BLBCTBOBICS of hypoxia on the poststress activation of the Hicroelectronics and computers in medicine primary innune response A82-21268 482-20320

1-28 SUBJECT IBDBX BIBIATOBB E1ECTBOBIC BQOIPBEIT

HEDIC1L BQDIPHBHT HBTHABB Portable medical status and treatment system Photolysis of CH4-HH3 mixtures and PH3 as models [HASA-CB-1 67496] B82-17862 for the photochemical transformations on the BBDICA1 PBBSOBBBL primitive earth and Jupiter Coaparative study of several physiological A82-20914 parameters in the evaluation of functional BBIBIL ALCOHOLS condition In nurses Photoassisted carbon dioxide reduction and A82-21826 formation of twoand three-carbon compounds BBDICAl SCIEiCE prebiological photosynthesis Flow visualization technignes in medical and A82-20920 biological applications BICE A82-20778 Possible mechanism for chemical induction of BEDICiL SBBVICBS chromosome aberrations in male meiotic and Physical and physiological features of long-range postmeiotic germ cells of mice flight and its impact on patients [DE81-031999] H82-16700 482-19012 MICBOBIOLOGI First aid for thorax traumas: Thorax drainage Extreme environments - Are there any limits to life through suction - Beport on 25 cases A82-20869 A82-19016 Bicrobial life in cold saline environments MB1ABOIDII A82-20974 Belanoidin polymers as possible oxygen sinks in Effect of transmeridional flights on biorhythm of the pre-bictic oceans zone formation by Streptomyces levoris A82-20921 B82-16711 BEBBBAHB STBOCXOBBS BICBOELBCTBOSICS Investigation of the otolithic membrane of the Bicroelectronics and computers in medicine utricle of the guinea pig A82-21268 A82-20301 BICBOOBGABISBS Membrane lipids and the origin of life Extreme environments - Are there any limits to life 482-20943 A82-20869 HEHBBABES Ultraviolet selection pressure in the Prephanerozoic Condition of meningeal nervous system during ancient microorganism survival repeated exposure to transverse accelerations 482-20969 B82-16730 Bicrobiblogically-mediated mutagenic activity of Facilitated diffusion of snail non-electrolytes in crude oil the human red blood cell [PB82-105131] B82-16702 H82-17855 BICBOPBOBBS BBBI4L PEBFOBBAHCB The effects of microphones and facemasks on LPC ' Electroencephalographic correlates of the vocoder performance hemispheric functional asymmetry in the human [AD-A107908] N82-16744 brain BICBOSIBOCTOBB 482-21454 Oltrastructure of blood vessels and muscle fibers Certain features of cerebral hemodynaaics in doing of rat skeletal muscles after flights aboard mental work at different air temperatures Cosmos-605 and Cosmos-782 biosatellites A82-21759 H82-17835 EEG evaluation of mental stress BICBOiA»B 4BTBHB4S A82-21784 The thermal response of a human in the near-zone Bationalizing physical regimen of sedentary workers of a resonant thin-wire antenna A82-21818 482-22206 A program for assessing pilot mental state in BICBOBAVE PBOBBS flight simulators Beasurement of radio freguency permittivity of [AIAA PAPEB 82-0257] A82-22078 biological tissues with an open-ended coaxial BE TAB Oil SB line. I Phylogenetic sequence of netabolic pathways in 482-20891 Precambrian cellular life Measurement of radio freguency permittivity of A82-20967 biological tissues with an open-ended coaxial Metabolic change in test animals as an indicator line. II - Experimental results of the biological effect of an electromagnetic 482-20892 field having a frequency of 50 Hz Waveguide technique for the calibration of 482-21758 miniature implantable electric-field probes for Effects of temperature on the duration of arousal use in microwave-bioeffects studies episodes during hibernation 482-20893 A82-21934 BIDDLB BAB Hetabolic processis in rat skeletal muscles after Peculiarities of the middle ear structure in flight aboard Cosmos-936 rodents as an index of the freguency tuning of B82-17833 their auditory system Comparative biochemistry and metabolism. Part 2: A82-21714 Naphthalene lung toxicity Characteristics of the structure and functions of [AD-A107673] B82-17842 the middle ear of lizards Comparative biochemistry and metabolism. Part 1: A82-21823 Carcinogenesis HILIT&BI AIBCHAFT [AD-A107614] M82-17865 Flight simulation - The military need BB1AJ. I01S 482-20529 Template-directed synthesis of oligoguanylic acids BILIT4BI OPBBATICBS .- Betal ion catalysis Physical performance tasks required of 0. S. A82-20932 Marines operating in a desert environment BBTEOBITIC COBPOSITIOH £40-4107866] 1182-17863 Organic analysis of the Antarctic carbonaceous BIBBS (BXCAfATIOBS) chondrites Physical health of truck drivers in the open-pit A82-20908 mining industry of the far north Abiotic organic synthesis in space A82-21805 482-20910 BIBIATOBE ELECTB01IC EQOIPBBBT Organic matter in meteorites and Precambrian rocks Haveguide technique for the calibration of - Clues about the origin and development of miniature implantable electric-field probes for living systems use in microwave-bioeffects studies 482-21988 A82-20893 BETBOBOL06IC4L PABABBTBBS Effects of embient parameters on man H82-17826

1-29 HIOSIS SUBJECT IBDEX

BIOSIS HOHOS4CCHABIDES Possible mechanism foe chenical induction of Abiotic synthesis of phosphoric esters of chromosome aberrations in male meiotic and nonosaccharides according to the 'cold model' postmeiotic gem cells of mice 482-20923 [DE81-03 1999] B82-16700 HOSTBOBILLOBITB aiTOCHOBDfiJA Clay-mediated reactions of HCH oligomers - The Evolution of the rhodospirillaceae and effect of the oxidation state of the clay mitochondria - A view based oil sequence data 482-20917 482-20972 On the polycondensation of amino acid adenylates lie effect of low temperature on the activity and on montmorillonites substrate specificity cf nonoamine oxidases in 482-20939 rat brain mitochondria Polymerization of serine gnanylate in the presence 482-21735 of montmorillonite Mechanisms for the regulation of the intracellular 482-20940 calcium distribution Possible selective adsorption of enantiomers by 482-21774 Ba-montmorillonite Enzymatic capacities of skeletal muscle - Effects 482-20946 of different types of training HOBPHIHB 482-22248 The effects of narcotic analgesics on animal HOISIDBE COBTBBT sensitivity to hypoxia Storage stability and improvement of intermediate 482-20316 moisture foods, phase 5 4 comparative evaluation of the hemodynamic [HAS4-CB-167503] H82-16742 effects of large doses of morphine, dipidolor, HOLBCOLAB BIOLOGY pentazocine, and phentanyl Resolution of underivatized amino acids by high 482-21795 pressure liquid chromatcgraphy, using chiral aOBPHOLOGI eluants The structural and functional organization of the 482-20914 ventrolateral nucleus of the thalamns Stereoselective interactions of small biological 482-21455 molecules Peculiarities of the middle ear structure in 482-20915 rodents as an index of the frequency tuning of Evolving nucleotide binding surfaces their auditory system 482-20954 482-21714 Organic geochemistry of the Isua supracrustals Changes in the structure and cellular composition 482-20961 of the inguinal lymph nodes of white rats Experiments on transfer of organic molecular subjected to static and dynamic stresses information into crystal lattice superstructures A82-21761 A82-20966 Oecussations in the human muscular system Phylogenetic sequence of metabolic pathways in 482-21762 Precambrian cellular life Cytokinetic evaluation of erythropoiesis during A82-20967 long-term orbital flights The evolution of blue-greens and the origins of B82-16715 chloroplasts Condition of meningeal nervous system during 482-20971 repeated exposure to transverse accelerations Cellular and molecular bases of local immunity B82-16730 482-21773 HOTIOH FEBCBPTIOB HOLECOL4B CLOUDS auditory depth perception - localization of Interstellar molecules and the origin of life nonmoving and moving sound sources 482-20902 482-21727 On the origin of organic molecules in interstellar HOTIOH SICKHESS space and some of its consequences 4 statistical examination of three approaches for A82-20904 predicting motion sickness incidence H01ECOLAB SIBOCIOBE 482-21685 The radiolysis and radioracenization of amino Acceleration measures and motion sickness incidence acids on silica surfaces [4D-A107996] B82-16734 482-20019 flOIIOB STABILITY A model for the enantiomeric enrichment of Biped walking - Model problems of dynamics and polypeptides on the primitive earth control 482-20020 A82-18977 Stereoselective interactions of small biological HODBTAIB IBHABITAHTS molecules Oxygen transport in dogs native to high altitudes 482-20945 during exercise Competition, coexistence and irreversibility in A82-21719 models of early molecular evolution HOOHTAIBS 482-20951 Functional condition and work capacity under Evolving nncleotide binding surfaces mountain conditions 482-20954 A82-20313 Secondary structures of pclypeptides as HDSCLES evolutionary growing points Cellular mechanisms of the Frank-Starling phenomenon 482-20962 482-21456 BOBAOB4L SIGBALS Differentiation of muscles on the basis of Human auditory brainstea electric responses to trace-element composition binaural and monaural stimuli 482-21704 H82-17861 The relationship between carbohydrate and lipid HOIKEIS metabolisms in muscle cell energetics under the Muscle, motor cortex, cerebellar nuclear, and influence of 4TPase loading - Mathematical model spindle afferent during slow hold-ranp-hold 482-21706 position-tracking movements of the monkey's wrist Decussations in the human muscular system S82-17854 482-21762 HOIOCHBOUIZC BADIATIOB 4 study of tropomyosins in human muscular and Genetic damage in Escherichia coli K12 4B2480 by nonmuscular organs broad-spectrum near-ultraviolet radiation 482-21806 482-22200 Cathepsin activity of skeletal muscle and aOBOCOLAB ?ISIOB myocardia myofibrils after exposure to The prevalence of visual deficiencies among 1979 weightlessness and accelerations general aviation accident airmen B82-16714 482-21688

1-30 SUBJECT IBDEX HABCOSIS

Activity of some enzymes of carbonbydrate Characteristics and patterns of the individual metabolism ID rat skeletal muscles after space development of male and female rats in the light flight of the energy rule of skeletal muscles H82-17834 A82-21721 Oltrasttucture of blood vessels and auscle fibers Oecussations in the human muscular system of rat skeletal muscles after flights aboard A82-21762 Cosmos-605 and Cosmos-782 biosatellites An electron microscope study of hyperplasia in H82-17835 fibers of the skeletal muscles of athletes Muscle, motor cortex, cerstellar unclear, and A82-21764 spindle afferent during slow hold-ramp-hold The source of reparative regeneration in skeletal position-tracking movements of the monkey's wrist muscle tissue N82-17854 A82-21768 HOSCOLAB F&TI6UE 1DH isoeuzyne spectrum in intact and denervated Clinical results on thymectomy in patients with skeletal muscles of rats of various age during myopathy in relation to the degree of muscular cold adaptation weakness A82-21798 A82-21755 Enzymatic capacities of skeletal muscle - Effects HOSCOLAB FOBCTIOB of different types of training Alterations in responses to drugs of atria from A82-22248 white rats acclimated to hypobaric hypoxia BOXAGEHS A82-19497 Hutagens and carcinogens - Occurrence and role The role of extracellular 02 and C02 tensions in during chemical and biological evolution membrane mechanisms of cerebral arterial smooth A82-20975 muscle regulation Hicrobiologically-mediated mntagenic activity of A82-19747 crude oil The influence of muscular work on the vestigial [PB82-105131] H82-16702 effects of cold acclimation BOTAXIOBS A82-19749 A mathematical method for the enumeration of Contractile dysfunction of vascular wall smooth doublet codes in genetic coding theory muscle under emotional nociceptive stress A82-20953 A82-20322 Possible mechanism for chemical induction of Investigation of recurrent inhibition in the human chromosome aberrations in male meiotic and spinal cord during static skeletal muscle activity postmeiotic germ cells of mice A 82-2 0330 [DE81-031999J B82-16700 Pulse rate evaluation of the relative Bicrobiologically-nediated mntagenic activity of physiological intensity of aerobic muscular work crude oil A82-20331 [PB82-105131] N82-16702 .The economy of muscular work during unfused tetanus BIOCABDIA1 IBFABCTIOB A82-21701 Mortality in acute myocardial infarction as Effect of calcium on the temporal characteristics function of geomagnetic field activity in Yerevan of muscle contraction N82-17852 A82-21708 BIOCABDIDB Study of the electrical activity of tie The temperature dependence of the kinetics of extraocular muscles isometric myocardium relaxation A82-21731 A82-19748 Nucleic acid and protein metabolism in cardiac Cellular mechanisms of the Frank-Starling phenomenon muscle A82-21456 A82-21772 Effect of cooling of the rhythmo-inotropic ratio The effect of the prolonged administration of in a pathologically altered myocardium sodium hydroxybutyrate on the physical work A82-21740 capacity and muscle tissue state of rats Clinical results on thymectomy in patients with A82-21779 myopathy in relation to the degree of muscular Types of spontaneous discharges in muscle receptors weakness A82-21789 A82-21755 Metabolic processes in rat skeletal muscles after Nucleic acid and protein metabolism in cardiac flight aboard Cosmos-936 muscle N82-17833 A82-21772 Muscle, motor cortex, cerefcellar nuclear, and The dynamics and physiological importance of the spindle afferent during slow hcld-ramp-hold activation of the gamma-amino-butyric acid position-tracking movements of the monkey's wrist system in the brain and cardiac muscle under N82-17854 pain and emotional stress HOSCDLAB STBBBGIB A82-21808 Evaluation of maximal and submaximal static muscle Lipid spectrum of the myocardium of white rats exertions exposed to hypoxic hypoxia A82-19223 N82-16724 Bioenergetic characteristics of various kinds of Myocardial protein fractious and enzymatic physical loads activity thereof in experimental rats flown A82-20334 aboard Cosmos-936 biosatellite The effect of two years' training of aerobic power N82-17832 and muscle strength in male and female cadets Features of metabolic disturbances in rat A82-21678 myocardium under effect of alternating magnetic Clinical results on thymectomy in patients with fields of different parameters myopathy in relation to the degree of muscular N82-17846 weakness HIOELBCTBIC POTEHTIA1S A82-21755 Begulation of calcium current and calcium activity Regulation of calcium current and calcium activity in heart cells in heart cells N82-17870 H82-17870 BOSCOLAB TOBOS The dynamics of muscular relaxation following N unfused tetanuses of different durations BAPBIHALBBE A82-21707 Comparative biochemistry and metabolism. Part 2: study of the electrical activity of the Naphthalene lung toxicity extraocular muscles [AD-A107673] N82-17842 A82-21731 BABCOSIS aOSCOLOSKELETAL SISTBH Computer-aided analysis of the effect of the Investigation of recurrent inhibition in the human initial narcosis on the central hemodynamics spinal cord during static skeletal muscle activity A82-21797 A82-20330

1-31 BABCOTICS SUBJECT IBDBZ

•ABCOIICS The use of linear models for EEG analysis The effects of narcotic analgesics on animal A82-20326 sensitivity to hypoxia HBOBOTBABSHITTBBS A82-20316 Hechanisns for the regulation of the iotracellnlar & comparative evaluation of the hemodynauic calcium distribution effects of large doses cf morphine, dipidolor, A82-21774 pentazocine, and phentanyl IEOTBOH IBBADIATIOB 482-21795 Absence of the additive effect in the combined BAVIG&XIOB irradiation of Cre pis capillaris seeds and Study of homing pigeons in Brazil: Some seedlings by gamna rays and neutrons preliminary results A82-21723 [IHPE-2248-PBE/032] H82-17839 HITBIiES HA VI The Strecker synthesis in the primitive ocean Complex physiological-hygienic characteristics of chemical evolution a new work-rest regine for seamen A82-20919 A82-21748 The polymerization products of HEAB OLIBAVIOLET BADIATIOB alpha-aminopropionitrile - The component Genetic damage in Escherichia coli K12 AB2480 by separation using cation-exchange resin broad-spectrum near-ultraviolet radiation A82-20934 A82-22200 SITBOGEH HEBDLAE Amino acids derivatives synthesis from nitrogen, Interstellar molecules and the origin of life carbon and Hater by electric discharges A82-20902 A82-20018 NEODIBIOH LASEBS HITBOGEB COHPOOBDS Biophysical fundamentals and instrumentation for Bates of fixation by lightning of carbon and the endovesical Bd:IAG-laser application nitrogen in possible primitive atmospheres tumor therapy A82-20016 [HBB-OA-581-81-0] H82-17843 Hitrogen compounds in carbonaceous meteorites - A BEEVES reassessment LOH isoenzyme spectrum in intact and denervated A82-20909 skeletal muscles of rats of various age during BITBOGBB BEXABOLISn cold adaptation Features of metabolic disturbances in rat A82-21798 myocardium under effect of alternating magnetic The role of intestinal nerves in the nutrient fields of different parameters induced intestinal hyperemia B82-17846 N82-17869 BOISE (SODHD) HBUBOHUSCOLAB TBAHSBISSI01 The reliability of flight personnel during the Investigation of recurrent inhibition in the human operation of the Si-4 helicopter spinal cord daring static skeletal muscle activity A82-19014 A82-20330 BOISE IBIEBSITI XEOBOBS Cochlear analysis of sound intensity and some Vestibular responses of neurons in the feline mechanisms of auditory sensations anterior suprasylvian gyrus and their A82-21792 interaction vith responses to acoustic and BOISE HBASOBEHEBI facial stimuli flethods for diagnosing hearing loss in workers A82-20309 exposed to high noise levels in accordance with The myenteric plexus - Basic principles of state standards modeling neuronal organization A82-21793 A82-20337 A study of the acoustic reflex as elicited by Filtration properties of receptive fields of selected environmental noise stimuli visual-cortex neurons H82-17858 A82-21470 BOISE POLLOTIOH A histochemical investigation of the microvascnlar Hygienic standards for industrial noise effectors regulating the supply of blood to the A82-21794 cerebral cortex BOISE BEDDCTIOH A82-21744 The effects of microphones and facemasks on LFC Acute experimental emotional stress in rabbits vocoder performance /physiological and cjtochemical aspects/ {AD-A107908J H82-16744 A82-21825 HOISB THBESBOLD Electrode unit for testing human H reflex Temporal integration of acoustic power for H82-16728 interrupted stimuli at suprathreshold levels BEOB0PHYSIOLOGY N82-17856 The healthy and the diseased human brain A study of the acoustic reflex as elicited by Bussian book selected environmental noise stimuli A82-18872 H82-17858 The myenteric plexus - Basic principles of BOISE TOLEBAHCE modeling neuronal organization Noise and vibration effects on vestibnlar and A82-20337 visual functions in teenagers The structural and functional organization of the A82-21747 ventrolateral nucleus of the thalanus Physiological-hygienic substantiation of A82-21455 admissible noise level in school rooms in a hot Filtration properties of receptive fields of climate visual-cortex neurons A82-21749 A82-21470 Features of the reaction to noise of the spinal The circadian rhythm of activity of adrenergic capillaries of white rats nerve fibers in the dura mater of rats A82-21767 A82-21743 BOBELEC1BOLI1ES Neuronal-glial alterations in the cerebral cortex Facilitated diffusion of small non-electrolytes in of animals under the influence of vhite noise the human red blood cell A82-21769 N82-17855 Comparative neurophysiological characteristics of BOBADBEBA1IBE cold and caudate tremors Functional condition of the rat sympato-adrenal A82-21790 system during emotional and nociceptive stress BBOBOPSYCHIATBI A82-20335 Models of a functional lapse in one hemisphere and Activation of succinate dehydrogenation in rat of the neuropharmocological effects on the deep liver by noradrenalin, cAHP and acute cooling structures of the brain A82-21734 A82-20325

1-32 SOBJECT IBDBI OfilHOSIiTIC T01BHAHCB

Norepiaephrine and enzymes of synthesis and OPBBAIOBS (EEBSOHHBL) degradation thereof in the rat hypothalamus Time domain identification of an optimal control following flight aboard the Cosu.os-936 pilot model with emphasis on the objective biosatellite function H82-16716 [HAS4-CB-168487] N82-17874 BOBBPIBEPHBIHB OPHIBA1BOLOGI Horepinephrine and enzymes of synthesis and Method of recording rotatory eye reflexes degradation thereof in the rat hypothalamus N82-16727 following flight aboard the Cosmos-936 OPIICAL ACIITI1I biosatellite 4 model for the enantiomeric enrichment of H82-16716 polypeptides on the primitive earth Stationary magnetic fields and reticalar 482-20020 influences on adrenergic and cholinergic systems Search for effect of longitudinally polarized H82-16725 protons on optically active amino acids IOCLE4SE 482-20021 Blood serum cuclease activity in healthy persons Besolntion of underivatized amino acids by high and patients with various hematological diseases pressure liquid chromatography, using chiral 182-21813 eluants HOCLEIC ACIDS 482-20944 A theory of the origin of life Stereoselective interactions of small biological 482-20023 molecules Beduction of thionucleosides - A prebiotic pathway 482-20945 to deoxyribonucleosides OPIICAL 1BACKIHG A82-20928 Study of the electrical activity of the The dynamics of protein and nucleic acid content extraocular muscles in rat raphe nucleus cells after total 482-21731 deprivation of sleep /in a rotating cylinder/ OPTIHAL COBTBOL and selective deprivation of its paradoxical phase Biped walking - Hodel problems of dynamics and 482-21718 control 10CLEOSIDBS A82-18977 Beduction of thionucleosides - A prebiotic pathway OBBITAL ASSBBBLI to deoxyribonucleosides lorking in space Book 482-20928 482-20772 IOCLBOTIDBS ORBITAL 10BKEBS Polymerization of serine guauylate in the presence working in space Book of montmorillonite 482-20772 482-20940 OBGABIC CUEBIS1BI f Evolving nucleotide binding surfaces Organic chemical evolution of reducing model of A82-20954 the atmosphere of the primitive earth - Bole of Summary of evidence for an anticodonic basis for UV light and electric discharges the origin of the genetic code 482-20912 482-20958 Experiments on transfer of organic molecular DHA-protein complex from an extreme halophile - 4 information into crystal lattice superstructures histone-like protein in archaebacteria A82-20966 482-20970 0EGABIC COHEOUBDS •OTBIBBIS New data on abiogenic synthesis of prebiological The role of intestinal nerves in the nutrient compounds in volcanic processes induced intestinal hyperemia A82-20017 B82-17869 Cometary material and the origins of life on earth •UIBITI01AL BEQOIBEBEH1S 482-20867 In-flight diets and guantitative adequacy thereof On the origin of organic molecules in interstellar to pilot expenditure space and some of its conseguences N82-17813 482-20904 Diet of crews of three main expeditions aboard Nature and origin of organic molecules in comets Salyut-6 orbital station 482-20906 H82-17815 Formation of prebiotic precursors from model reducing atmospheres Bole of hydrogen escape 482-20911 Organic and inorganic interpretations of the OASES Martian DV-IB reflectance spectrum Microbial life in cold saline environments 482-21208 482-20974 OBGAHIC MAIEBIALS OCEAH HODBLS Organic analysis of the Antarctic carbonaceous Genesis of amino acids in the primeval sea - chondrites Formation of amino acids from sugars and ammonia 482-20908 in a modified sea medium Abiotic organic synthesis in space A82-20925 482-20910 OCOLOBEIEBS Organic matter in meteorites and Precambrian rocks Differences in eye movement data recorded by - Clues about the origin and development of electro-ocnlography and corneal reflection living systems technigues 482-21988 A82-19224 OBGABIC EBOSPHOBOS COHPOOBDS OCDLOBOIOB BEEVES Formation of energy rich phosphate in Fenton's Study of the electrical activity of the reaction for prebiotic conditions extraocnlar muscles A82-20922 482-21731 OBGAHOBEIAILIC COHPOOiDS OPBBATOB PEBFOBBABCE Porphyrin-like compounds genesis under simulated Computer simulation as a visual aid in a video abiotic conditions course for ATC system performance A82-20926 A82-19248 OE1BOSTAIIC T01BHABCE Physical health of truck drivers in the open-pit Orthostatic fluid-electrolyte and endocrine mining industry of the far north responses in fainters and nonfainters A82-21805 A82-19492 Mathematical model of a human operator detecting a Postnrography of ataxia induced by Coriolis- and signal on a noise background Purkinje-effects A82-21893 ' A82-21684 Question of redistribution of blood in orthostatic position H82-16705

1-33 OSCILLATIOBS SOBJBCI IBDBX

Jugular, right atrial pressure and cerebral The measurement of oxygen and carbon dioxide bemodynamics of healthy aan submitted to partial pressures in tissues by the gas depot postural tests method 882-17825 A82-20318 OSCILLATIOHS A combined method for the study of tissue Effects on biological systems of electromagnetic respiration under conditions corresponding to oscillations in millimeter range of wavelengths natural gas homeostasis H82-17819 A82-20321 OTOLABIIGOLOGI OXIGBB4TIOH The functional condition of the ampullae apparatus Variability of oxygen affinity of blood - Human in Heniere's disease subjects native to high altutude A82-20308 A82-19493 Deontology in the practice of otorhinolaryngology OZOHE 482-20312 Comets and the photochemistry of the paleoatmosphere OT01ITH OBGAIS A82-20866 Investigation of the otolithic membrane of the Effects of long-term exposure to low levels of utricle of the guinea pig ozone - A review A82-20301 A82-21676 OXIDASB Variation in plant response to ozone: A Brain monoamine ozidase activity during cold conceptual model of physiological events adaptation and under the combined Effects of [DE81-029692] H82-16701 cold and hyperbaric ozygenation Health effects of carbon monoxide and ozone A82-19746 £PB82-114265] H82-17866 The effect of low temperature on the activity and substrate specificity of monoamine ozidases in rat brain mitochondria A82-21735 PAIEOBIOLOGI Succinate dehydrogenase and cytochrome ozidase Ultraviolet selection pressure in the Prephanerozoic activity in tissues of rats submitted to ancient microorganism survival long-term hypokinesia A82-20969 882-16723 PATHOGEHESIS OXIDATIOI Cardiovascular origins of heatstroke Clay-mediated reactions of HCH oligcmers - The pathophysiology - An anesthetized rat model effect of the oxidation state of the clay A82-21687 A82-20917 Emotional stress as a factor in cardiovascular Formation of energy rich phosphate in Fenton's disorders reaction for prebiotic conditions A82-21796 A82-20922 Prevention of staphylococcal infections during OXIGBS space flights Helanoidin polymers as possible oxygen sinks in 882-17818 the pre-biotic oceans PATHOLOGICAL EFFECTS A82-20921 Physiology and pathology of respiration and means The use of oxygen as the test gas in the of correcting oxygen deficiencies in an organism determination of the closing volume of /Meeting of the Interdepartmental Commission on respiratory ducts the Coordination of Studies in Medicine of the A82-21801 Academy of Sciences of the Ukrainian SSB and the Distinctions of regeneration of confined Ministry of Health of the Ukrainian SSB/ atmosphere b; means of photosynthesis of A82-20303 unicellular algae PATIBBTS 882-16720 Physical and physiological features of long-range OXYGEB COISDHPTIOH flight and its impact on patients Brain monoamine oxidase activity during cold A82-19012 adaptation and under the combined effects of PEHTOBABBITAL SODIUH cold and hyperbaric oxygenation Alterations in responses to drugs of atria from A82-19746 white rats acclimated to hypobaric hypoxia The role of extracellular 02 and C02 tensions in 482-19497 membrane mechanisms of cerebral arterial smooth PBPTIDES muscle regulation Parameters of the interaction of bradykinin with A82-19747 cardiovascular system receptors Elevation of hypoxia resistance with the use of A82-20332 gutimine Clays as prebiotic photocatalysts A82-20319 A82-20916 Pulse rate evaluation of the relative Histidyl-histidine catalysis of glycine physiological intensity of aerobic muscular work condensation in fluctuating clay environments 182-20331 A82-20952 The effect of two years' training of aerobic power PBBCEPTIOB and muscle strength in male and female cadets An analysis of cognitive mapping skill A82-21678 {AD-A106145] 882-16740 Oxygen transport in dogs native to high altitudes Ability differences and cognitive mapping skill daring exercise [AD-A106389] 882-16741 A82-21719 PEBFOBHABCB PBBDICTIOI OXTGEI BASES Predicting the potentials of young swimmers based The effects of microphones and facenasks on LPC on clinical and physiological data vocoder performance A82-21814 [AD-A107908] H82-16744 PEBIPBEBAL CIBCOLATIOH OXYGEB HETABO1ISH Change in the cytocheoical indicators of Peroxidation of lipids in the liver and lungs of carbohydrate metabolism in the peripheral blood rats during prolonged adaptation to the cold neutrophils of pilots A82-21736 A82-21457 Effects of pyrroxane and methylapogalantaoine on EEBIPBEBAL BEBVOOS SISIEH cerebral blood circulation and oxygen regime Condition of meningeal nervous system during A82-21776 repeated exposure to transverse accelerations OXIGBB TBISIOi H82-16730 Variability of oxygen affinity of blood - Human FEBHITTIVIXI subjects native to high altutude Measurement of radio frequency permittivity of A82-19493 biological tissues with an open-ended coaxial line. I A82-20891

1-34 SUBJECT IBDBI PHISIC4L EXEHCISB

Heasurement of radio frequency permittivity of Possible role of phosphine in chemical evolution biological tissues with an open-ended coaxial 482-20915 line. II - Experimental results PHOTOOXIB4TIOi 482-20892 Bhodopsin aggregation under the damaging effects PEBOXIDES of light on the photoreceptor membranes Peroxidation of lipids in the liver and lungs of 482-21705 rats during prolcnged adaptation to the cold PHOTOBBCBETOBS 482-21736 Psychophysical evidence for more than two kinds of PEBSOIHEL cone in dichromatic color blindness Lavs governing readaptaticn for seamen after a 482-19608 low-latitude cruise Bhodopsin aggregation under the damaging effects 482-20310 of light on the photoreceptor membranes PESTICIDES 482-21705 Chemicals Identified in Hunan Biological Media CHOSOSEBSIIIVI1I [DE81-030813] H82-16735 Psychophysical evidence for more than two kinds of PETBOLOGi cone in dichromatic color blindness Organic matter in meteorites and Precambrian rocks 482-19608 - Clues about the origin and development of PHOTOSYSTHBSIS living systems Photoassisted carbon dioxide reduction and 482-21988 formation of twoand three-carbon compounds PH4BH4COL06I prebiological photosynthesis Elevation of hypoxia resistance Kith the use of 482-20920 gutimine Evolution of the rhodospirillaceae and 482-20319 mitochondria - 4 view based on sequence data Models of a functional lapse in one hemisphere and 482-20972 of the neuropharmocological effects on the deep On the origin of photosynthetic eukaryotic cells - structures of the brain Cyanidium caldarium as a 'bridge* alga between 482-20325 prokaryotic cyanobacteria and eukaryotic Plow visualization techniques in medical and rhodophytes: Evidence from environmental, biological applications polysaccharide biochemistry and ultrastructural 482-20778 studies The effects of horizontal body casting on blood 482-20973 volume, drug responsiveness, and »6z tolerance Distinctions of regeneration of confined in the rhesus monkey atmosphere by means of photosynthesis of 482-21682 unicellular algae Effects of pyrroxane and oethylapogalantamine on H82-16720 cerebral blood circulation and oxygen regime The structure and function of chlorophyll-proteins 482-21776 in photosystem 1 and the light harvesting The effect of piracetam on the body's resistance complex of photosystem 2 to hypoxia N82-17811 482-21777 PHYSICAL CHEHISTBI Comparative neurophysiological characteristics of Storage stability and improvement of intermediate cold and caudate tremors moisture foods, phase 5 482-21790 [H4S4-CB-167503] 8.82-16742 PHOSPH4TES PHISICAL EXEBCISB Formation of energy rich phosphate in Fenton's Effect of blood volume on sweating rate and body reaction for prebiotic conditions fluids in exercising humans 482-20922 482-19495 Characteristics of the relations of the primary Enhanced heat production in physically restrained responses of the pentose phosphate pathway to rats in hypoxia glycolysis in the bone marrow of irradiated rats 482-19496 482-21725 The influence of muscular work on the vestigial PflOSPBIMES effects of cold acclimation Photolysis of CB4-HB3 mixtures and PB3 as models 482-19749 for the photochemical transformations on the Microcirculation, tolerance to physical strain, primitive earth and Jupiter and certain homeostasis parameters in patients 482-20914 with angina pectoris Possible role of phosphine in chemical evolution 482-20324 482-20915 Pulse rate evaluation of the relative PHOSPHOBOS COHP008DS physiological intensity of aerobic muscular work Abiotic synthesis of phosphoric esters of 482-20331 monosaccharides according to the 'cold model* Bioenergetic characteristics of various kinds of 482-20923 physical loads Mammalian toxicological evaluation of DIHP and 482-20334 DCPD (Phase 3 - IBP4) 4 study of treadmill exercise protocols for [4D-4107574] 882-17840 Chinese males PHOSPHOBOS METABOLISM 482-21677 Features of metabolic disturbances in rat The effect of two years' training of aerobic power myocardium under effect of alternating magnetic and muscle strength in male and female cadets fields of different parameters 482-21678 N82-17846 Changes in the main characteristics of the central PHOTOCHEHIC4L BE4CTIOBS hemodynamics of healthy individuals and Comets and the photochemistry of the paleoatmosphere hypertension patients during physical exercise 482-20866 482-21711 Clays as prebiotic photocatalysts Oxygen transport in dogs native to high altitudes 482-20916 during exercise Coupling to solar energy: Sensitized 482-21719 photoreactions - The primary source of The effect of physical training on the lipid and self-organization lipoprotein metabolism in people of various ages 482-20968 482-21757 PHOTOLYSIS The physical activity of humans as a social and Far 0V photolysis of methane-water gaseous biological problem mixtures and the prebiotic synthesis of aldehydes 482-21760 482-20913 Changes in the structure and cellular composition Photolysis of CH4-SH3 mixtures and PH3 as models of the inguinal lymph nodes of white rats for the photochemical transformations on the subjected to static and dynamic stresses primitive earth and Jupiter 482-21761 482-20914

1-35 PHYSICAL FiCtOBS SDBJECT IHDEX

An electron nicroscope study of hyperplasia in The influence of adaptation on the periodic effect fibers of the skeletal muscles of athletes of hypoxia on the poststress activation of the A82-21764 primary immune response 4daptogenic effect of mebicar daring emotional 482-20320 stress, exercise, and hypoxia The effects of successive ionizing radiation and 482-21780 heat on antibody formation Functional state of the hippocampal-reticular A82-21751 complex under snbmaximal physical load and fatigue The effect of piracetam on the body's resistance 482-21786 to hypoxia Seasonal rhythm of the immune reactivity and heart A82-21777 tolerance to physical load in patients irith The mathematics of immunity response to viral ischemic heart disease intrusion 482-21802 482-21824 Semesterified fatty acid netabolisn during PHYSIOLO6IC4L EFFECTS exercise in humans Physical and physiological features of long-range 482-21809 flight and its impact on patients The dynamics of heart rate recovery following work 482-19012 of various aerobic intensities Enhanced heat production in physically restrained 482-21815 rats in hypoxia Development of an autonatic data bank for managing A82-19U96 physical education of students The influence of muscular work on the vestigial 482-21816 effects of cold acclimation Rationalizing physical regimen of sedentary workers A82-19749 482-21818 Laws governing readaptation for seamen after a Effect of the functional properties of the low-latitude cruise vestibular analyzer on the effectiveness of 482-20310 instruction in gyanasties The effects of narcotic analgesics on animal 482-21819 sensitivity to hypoxia Mechanisms of adaptation to ergotheraic hypoxemia 482-20316 in athletes specializing in different sports The effects of an aqueous potassium loading test 482-21820 on kidney function Badiometric determination of potassium content in 482-20329 athletes Effects of long-term exposure to low levels of 482-21822 ozone - A review Increased excretion of urea and 482-21676 M/tau/-methylhistidine by rats and humans after Cardiovascular origins of heatstroke a bout of exercise pathophysiology - An anesthetized rat model 482-21927 482-21687 PHYSICAL F4CTOBS Changes in morphological and cytogenetic Fatigue in Flight Inspection Field Office (FIFO) hematopoietic indicators in hamadryas baboons flight crews exposed to chronic low-level radiation [4D-4106791] B82-16733 482-21726 PHYSICAL PITIESS Physiological-hygienic substantiation of EEC description algorithm for use in clinical admissible noise level in school rooms in a hot practice and studies of work capacity climate 482-2030IJ A82-217U9 The effect of two years' training of aerobic power The nltrastructure of the liver sinusoids of mice and muscle strength in male and female cadets under conditions of acute stress - Horphometric A82-21678 study Physical health of truck drivers in the open-pit A82-21782 nining industry of the far north The existence of an endogenous biorhythm in A82-21805 chromatin-positive cells of the buccal Stress and immunity in athletes epithelium in women 482-21821 482-21783 Comparative antihypoxic efficacy of pressure Variation in plant response to ozone: 4 chamber conditioning and fasting of man conceptual model of physiological events N82-16729 [DE81-029692] H82-16701 Physical performance tasks required of 0. S. Physiological and hygienic evaluation of vibration Marines operating in a desert environment in the cockpit of a cargo helicopter [AD-4107866] H82-17863 H82-16709 PHYSICAL IOBK Human reactions to elf electric and magnetic Evaluation of maximal and submaximal static muscle fields: An annotated bibliography of current exertions literature 482-19223 [PB82-102567] H82-16737 The economy of muscular work during unfused tetanus OSSB report: Space biology and aerospace 482-21701 medicine, vol. 15, no. 5, Sep. - Oct. 1981 The application of bicycle ergometry to the early £JPBS-793U6] H82-17812 detection of ischemic heart disease Effects of embient parameters on man A82-21775 H82-17826 Evaluation of the functional state of the Method of assessing individual resistance of rats cardiovascular system in patients with ischemic to hypoxic hypoxia heart disease with reference to the nature of N82-17837 their occupational activity Bespiratory toxicology, 1981 A82-21803 £40-4107672] H82-178U1 Fatigue in Flight Inspection Field Office (FIFO) Forward masking of auditory nerve (H sub 1) and flight crews brainstem responses (Have V) in humans [AD-A106791] 1182-16733 H82-17860 PHYSIOCHEBISZBY Health effects of carbon monoxide and ozone A study of tropouyosins in human muscular and £PB82-11«265] H82-17866 nonmuscular organs PHYSIOLOGICAL F4CTOBS A82-21806 Complex physiological-hygienic characteristics of PHYSIOLOGICAL DEFENSES a new work-rest regime for seamen The effect of the motor activity regime on the 482-217U8 development, conservation, and regeneration of Predicting the potentials of young swimmers based defensive conditioned reflexes in rats on clinical and physiological data 482-20305 482-2181U Natural resistance of the organisms of seamen during postcruise rest 482-20311

1-36 SUBJECT IBDBX POLLDTIOH C08TBOL

PHYSIOLOGICAL BBSP08SBS PHYSIOLOGICAL TBSIS Effects of vasopressin administration on diuresis Orthostatic fluid-electrolyte and endocrine of vater immersion in normal booans responses in fainters and nonfainters 482-19491 482-19492 Orthostatic fluid-electrolyte and endocrine Acute experimental emotional stress in rabbits in responses in fainters and nonfainters a modulated electromagnetic field 482-19492 482-20307 Variability of oxygen affinity of blood. - Huaan Difference between eye closure and visual subjects native to high altntude stabilization in the control of posture in man 482-19493 482-21686 Alterations in responses to drugs of atria from Neuronal-glial alterations in the cerebral cortez white rats acclimated to hypobaric hypoxia of animals under the influence of white noise 482-19497 482-21769 Vestibular responses of neurons in the feline The state of the vegetative functions during sleep anterior saprasylvian gyrns and their 482-21771 interaction with responses to acoustic and Phase ¥ of the single-breath washout test facial stimuli 482-21928 482-20309 PI6EOBS Special and clinical physiology of hypozic states Study of homing pigeons in Brazil: Some 482-20317 preliminary results Contractile dysfunction of vascular nail smooth [IBEE-2248-PBB/032] H82-17839 muscle under emotional nociceptive stress PILOT PBBFOBB4HCB 482-20322 The reliability of flight personnel during the The significance of airflov resistance to changes operation pf the ni-4 helicopter in responses to increasing hypercapnia 482-19014 482-20327 Change in the cytocheaical indicators of Parameters of the interaction of bradykinin with carbohydrate metabolism in the peripheral blood cardiovascular system receptors neutrophils of pilots 482-20332 482-21457 Functional condition of the rat sympato-adreaal 4 program for assessing pilot mental state in system during emotional and nociceptive stress flight simulators 482-20335 £4144 P4PEB 82-0257] 482-22078 Regional distribution cf cardiac output in Causes of fatigue among crews of civil aviation unanesthetized baboons during +Gz stress with helicopters and without an auti-G suit N82-16708 482-21681 Time domain identification of an optimal control Acceleration induced voltage variations in the pilot model with emphasis on the objective electrocardiogram daring exhaustive simulated function aerial combat maneuvering [H4S4-CH-168487] H82-17874 482-21683 PILOT II4IHISG Adaptation to high-altitude hypozia at different Advanced aviation concepts evaluation through ambient temperatures /before and during computer driven simulation human factors adaptation/ consideration in flight training simulator design 482-21715 482-19258 Metabolic change in test animals as an indicator Flight simulation - The military need of the biological effect of an electromagnetic 482-20529 field having a frequency of 50 Hz The semi-automatic instructional system of 482-21758 B-52 weapon system trainers The morphology of the lungs of dogs whose movement A82-20539 is completely restricted Development of the Automated Performance 482-21765 Assessment and Remedial Training System Features of the reaction to noise of the spinal (AP4B1S): 4 landing signal officer training aid capillaries of white rats [AD-4106224] H82-17873 482-21767 PLAHEIAHI ATMOSPHERES Lysosomes under conditions of stress Possible role of phosphine in chemical evolution 482-21770 482-20915 Adaptogenic effect of aebicar during emotional PL4HBT4BI EVOLUTION stress, exercise, and hypozia Liquid water on a planet over cosmic periods 482-21780 482-20907 The effect of chclinomimetics on the development PLASETABI SOBFACES of hypothermia Coupling to solar energy: Sensitized 482-21781 photoreactions - The primary source of The effects of emotional activation on the spatial self-organization synchronization of human brain biopotentials 482-20968 A82-21785 PL4BBTOLOGI Coordination of processes in the hierarchic Liquid water on a planet over cosmic periods structure of the visual analyzer 482-20907 A82-21788 PL4HT S1BBSS Types of spontaneous discharges in muscle receptors Variation in plant response to ozone: 4 482-21789 conceptual model of physiological events Acute experimental emotional stress in rabbits [DB81-029692] N82-16701 /physiological and cytochemical aspects/ PL4HTS (BOT4HI) A82-21825 Introduction prognosis and its methodological Comparative study of several physiological aspects plant growth in new habitats parameters in the evaluation of functional 482-21722 condition in nurses Absence of the additive effect in the combined A82-21826 irradiation of Crepis capillaris seeds and Erythrocyte indices during a competitive marathon seedlings by gamma rays and neutrons 482-21932 482-21723 Enzymatic capacities of skeletal muscle - Effects PHEDHOGB4PHI of different types of training Portable medical status and treatment system 482-22248 [HASA-CB-167496] H82-17862 In vitro Ca-45/++/ uptake and exchange by POLABIZAIIOH (SPIB ALIGHHEIT) otoconial complezes in high and low K/+/Sa/+/ Search for effect of longitudinally polarized fluids protons on optically active amino acids 482-22249 482-20021 Human auditory bcainstem electric responses to POLLOTIOH COBTBOL binaural and monaural stimuli Health effects of carbon monoxide and ozone H82-17861 £PB82-114265] H82-17866

1-37 POLIBBB CHBttlSTBI SOBJBCC IBDEX

POLIBEB CHEHISTBI Organic matter in meteorites and Frecambrian rocks Helajioidin polymers as possible oxygen sinks in - Clues about the origin and development of the pre-bictic oceans living systems A82-20921 A82-21988 The polymerization products of PBEDICTIOH AHAllSIS TBCHHIQOBS alpha-amincpropionitrile - The component A statistical examination of three approaches for separation using cation-exchange resin predicting motion sickness incidence A82-20934 A82-21685 P01THEBJZATIOB Introduction prognosis and its methodological Terrestrial evolution of polymerization of amino aspects plant growth in new habitats acids - Heat to ATP A82-21722 A82-20937 The dynamics of forming a prediction system in On the polycondensation of amino acid adenylates goal-directed behavior on montmorillonites A82-21730 A82-20939 PBESEBflHG Polymerization of serine gaanylate in the presence Storage stability and improvement of intermediate of montmorillonite moisture foods, phase 5 A82-20940 [NASA-CB-167503] H82-16742 Environmental conditions for the formation of PBESSOBE CBAHBEBS marigranules and kinetic studies on the formation Comparative antihypoxic efficacy of pressure • chemical evolution of amino acids in sea chamber conditioning and fasting of man medium H82-16729 A82-20942 Antihypoxic efficacy of intermittent mode of POLIBBBS pressure chamber conditioning of man Potentiometric titration behavior of polyamino H82-17827 acids prepared by thermal polycondensation PBBSSDBE DISTBIBOTIOS A82-20938 Evaluation of man's endurance of local pressure to POLYBDCI.EOIIDES the head and objective assessment of hygienic Origin of translation - The hypothesis of specifications for protective helmets permanently attached adaptors proposed H82-16710 prehiotic amino acid synthesis PBESSOBE HBASOBBHBST A82-20022 The measurement of oxygen and carbon dioxide POilPEPI'IDES partial pressures in tissues by the gas depot A model for the enanticmeric enrichment of method polypeptides on the priuitive earth A82-20318 A82-20020 PBESSOBE SOUS Secondary structures of polypeptides as Begional distribution of cardiac output in evolutionary growing pcints unanesthetized baboons during +Gz stress with A82-20962 and without an anti-G suit Search for primitive replicative properties on A82-21681 early polypeptides PBIHI1ITE BABTH ATHOSPHBBE A82-20963 Bates of fixation by lightning of carbon and An investigation of the biological activity of nitrogen in possible primitive atmospheres chalones separated from normal livers and from A82-20016 livers that are being regenerated Amino acids derivatives synthesis from nitrogen, A82-21742 carbon and water by electric discharges POPOLATIOH THEOBI A82-20018 A mathematical model of cell populations vith stem A theory of the origin of life cells A82-20023 A82-21702 Comets and the photochemistry of the paleoatmosphere POBPHIBIBS A82-20866 Porphyrin-like compounds genesis under simulated Organic chemical evolution of reducing model of abiotic conditions the atmosphere of the primitive earth - Bole of A82-20926 0V light and electric discharges POBTABLB EOOIPHEHT A82-20912 Portable medical status and treatment system Far DV photolysis of methane-water gaseods [HASA-CB-167496] H82-17862 mixtures and the prebiotic synthesis of aldehydes POSTOBB A82-20913 Posturography of ataxia induced by Coriolis- and Photolysis of CH4-HH3 mixtures and PH3 as models Purkinje-effects for the photochemical transformations on the A82-21684 primitive earth and Jupiter Difference between eye closure and visual A82-20914 stabilization in the control of posture in man Abiotic synthesis of phosphoric esters of A82-21686 monosaccharides according to the 'cold model* Positions, movements and egnilibrinm of rats after A82-20923 flights aboard biosatellites The role of analytical procedures in the formation 1182-16713 of biochemicals from experiments simulating the POTABLE iATBB chemical evolution of primeval earth Hygienic principles of ongoing monitoring of A82-20927 quality of recycled water during space flights Cyanamide mediated syntheses of leu, ala, and phe N82-16717 peptides under plausible primitive earth POT A SSI OH conditions Badiometric determination of potassium content in A82-20931 athletes Chemical evolution of model systems of primeval A82-21822 earth periphery and thermal polymerisation of POTASSIDH CHIOBIDBS aqueous solutions of cyanides The effects of an aqueous potassium loading test A82-20933 on Kidney function The cold theory of the origins of life - A82-20329 Assumptions for the theory and experimental POTEHMOHETBIC 1HALISIS evidence Potentiometric titration behavior of polyamino A82-20935 acids prepared by thermal polycondensation The appearance of protobiopolymers and A82-20938 protomembranes in accordance with the 'cold PBECAHBBIAI PEBJOD theory' of the origins of life Phylogenetic sequence of metabolic pathways in A82-20936 Precambrian cellular life Membrane lipids and the origin of life A82-20967 A82-20943

1-38 SPBJECI IIDBI PBOIOBIOLOGI

Evolution of the terrestrial atmosphere and its Cyanamide mediated syntheses of leu, ala, and phe fossils in biosystems peptides under plausible primitive earth 482-20960 conditions Hutagens and carcinogens - Occnrrence and role 482-20931 daring chemical and biological evolution Terrestrial evolution of polymerization of amino 482-20975 acids - Heat to ATP PBOBABILITI IBEOBI 482-20937 Choosing among alternatives vith uncertain Quantum mechanical conformational analysis of outcomes: Effect of prior curing and estimation aminoacyladenylates - Implication in the origin requirements of life [AD-4106143] B82-16739 482-20941 PBOBIBB S017IIG Evolutionary processes of the genetic code Pilot workload: A survey of operational problems 482-20957 [4D-4107758] 882-16745 Summary of evidence for an anticodonic basis for PHOGBOSIS the origin of the genetic code The possibility of using mathematical methods for 482-20958 predicting the results of the surgical treatment Primitive transfer ENS and origin of Darwinian of patients with vasorenal hypertension system 482-21709 482-20959 PBOPHIL4XIS Secondary structures of polypeptides as The role of natrinresis in the prophylactic effect evolutionary growing points of adaptation to hypoxia in the case of 482-20962 hereditary hypertension Search for primitive replicative properties on 482-21712 early polypeptides PBOSI4GLAHDIBS 482-20963 The effect of synaptically active drugs on the DMA-protein complex from an extreme halophile - 4 hyperthermic effect of prcstaglandin E2 in rats histone-like protein in archaebacteria . 482-21741 482-20970 PBOTBH HETABOLISH The structure and function of chlorophyll-proteins Could the biochemical metabolism be different in photosystem 1 and the light harvesting 482-20976 complex of photosystem 2 Some indicators of protein metabolism in H82-17811 erythrocytes during radiation sickness and Influence of electromagnetic waves in millimeter following cystamine injection band on inductoprotein synthesis of 482-21724 penicillinase by staphylococcus aureus Nucleic acid and protein metabolism in cardiac H82-17847 muscle PBOTEIBS 482-21772 The dynamics of protein and nucleic acid content The ultrastructure of the liver sinusoids of mice in rat raphe nucleus cells after total under conditions of acute stress - Horphometric deprivation of sleep /in a rotating cylinder/ study and selective deprivation of its paradoxical phase 482-21782 482-21718 Increased excretion of urea and An investigation of the biological activity of H/tan/-methylhistidine by rats and humans after chaloaes separated from normal livers and from a bout of exercise livers that are being regenerated 482-21927 482-21742 Cathepsin activity of skeletal muscle and 4 study of tropomyosins in human muscular and myocardia myofibrils after exposure to nonmuscular organs weightlessness and accelerations 482-21806 H82-16714 PBOTHBOHBIH Amino acid metabolism during prolonged intake of The role of urokinase in the regulation of the dehydrated foods and simulation of some space fibrinolytic activity of blood under normal flight factors conditions S82-17816 482-21799 Effect of space flights cf different duration on PBOTOBIOIOGY energy metabolism of human erythrocytes 4 model for the enantiomeric enrichment of S82-17817 polypeptides on the primitive earth Bat amino acid composition after flight aboard 482-20020 Cosmos-1129 biosatellite Search for effect of longitudinally polarized H82-17831 protons on optically active aoino acids Hyocardial protein fractions and enzymatic 482-20021 activity thereof in experimental rats flown Origin of translation - The hypothesis of aboard Cosmos-936 biosatellite permanently attached adaptors proposed 1182-17832 prebiotic amino acid synthesis Blood fibrinogen as related to immersion in water 482-20022 for seven days and short-term space flight 4 theory of the origin of life H82-17836 482-20023 PBOTBIB SIIXBESIS 4 neutral theory of biogenesis Origin of translation - The hypothesis of 482-20024 permanently attached adaptors —— proposed Comets and the origin of life; Proceedings of the prebiotic amino acid synthesis Fifth College Park Colloquium on Chemical 482-20022 Evolution, Dniversity of Maryland, College Park, 4 theory of the origin of life HD, October 29-31, 1980 482-20023 482-20853 Synthesis and degradation of amino acids by Chemical evolution of interstellar dust - 4 source contact glow discharge electrolysis, a possible of prebiotic material route for prebiotic formation of bio-organic 482-20863 compounds Are comets connected to the origin of life 482-20924 482-20865 Genesis of amino acids in .the primeval sea - Cometary material and the origins of life on earth Formation of amino acids from sugars and ammonia 482-20867 in a modified sea medium Comets - A vehicle for panspermia 482-20925 482-20868 Factors influencing the rate of non-enzymatic Origin of life; Proceedings of the Third ISSOL activation of carboxylic and amino acids by ATP Meeting and Sixth ICOL Meeting, Jerusalem, 482-20929 Israel, June 22-27, 1980 482-20901 Interstellar molecules and the origin of life 482-20902

1-39 PSICHO4COOSTICS SOBJECT IHDEX

Clays as prebiotic photocatalysts Psychological testing at high altitudes A82-20916 482-21679 The Strecker synthesis in the primitive ocean PSICHOHOTOB PBBFOBHAHCE chemical evolution Causes of fatigue among crews of civil aviation A82-20919 helicopters Chemical evolution of model systems of primeval H82-16708 earth periphery and thermal polymerisation of PSICHOPHISICS aqueous solutions of cyanides Psychophysical evidence for more than two kinds of 482-20933 cone in dichromatic color blindness The cold theory of the origins of life - 482-19608 Assumptions for the theory and experimental PSICHOPHJSIOLOGI evidence Psychological testing at high altitudes 482-20935 482-21679 The appearance of protobiopolvmers and Complex physiological-hygienic characteristics of protomembranes in accordance with the 'cold a new work-rest regime for seamen theory1 of the origins of life 482-21748 482-20936 Comparative study of several physiological Terrestrial evolution of polymerization of amino parameters in the evaluation of functional acids - Heat to 4IP condition in nurses 482-20937 482-21826 On the polycondensation of amino acid adenylates Cerebral hemispheric activity and automonic on montmorillcnites nervous function 482-20939 H82-17868 Quantum mechanical confoxmational analysis of PSICHOTBOPIC DBOGS aminoacyladenylates - Implication in the origin Change in the nature of the psychotropic effect on of life the emotional reactivity and behavior in stress 482-20941 situations depending on the state of the Environmental conditions for the formation of catecholaminergic systems of the brain marigranules and kinetic studies on the formation 482-21739 chemical evolution of amino acids in sea PDBLIC BE4LTH medium The biological effects of low-level ionizing 482-20942 radiation Hembrane lipids and the origin of life 482-20146 482-20943 The physical activity of hnmans as a social and Competition, coexistence and irreversibility in biological problem models of early molecular evolution 482-21760 482-20951 Health effects of carbon monoxide and ozone Histidyl-histidine catalysis of glycine [PB82-114265] H82-17866 condensation in fluctuating clay environments POLHOHABI CIBCOLATIOI 482-20952 The effect of blood pressure in the pulmonary Primitive transfer BH4 and origin of Darwinian artery on gas exchange in functionally system heterogeneous lungs 482-20959 482-21738 Evolution of the terrestrial atmosphere and its 4 comparative evaluation of the hemodynamic fossils in biosystems effects of large doses of morphine, dipidolor, 482-20960 pentazocine, and phentanyl Organic geochemistry of the Isua supracrustals 482-21795 482-20961 Air embolism - Possible role of surfactant on Search for primitive replicative properties on recompression early polypeptides 482-21931 482-20963 POLHOHABI FOHCTIOIS Selective acylability of amino acids by Changes in microcirculatory flow with respiratory non-enzymic model reactions of biochemical insufficiency transacylations 482-20323 482-20965 The significance of airflow resistance to changes DBA-protein complex from an extreme halophile - 4 in responses to increasing hypercapnia histone-like protein in archaebacteria 482-20327 482-20970 Pulmonary shunting and its regulation Evolution of the rhodospirillaceae and 482-21728 mitochondria - 4 vied based on sequence data Pulmonary gas exchange during altered density gas 482-20972 breathing Hutagens and carcinogens - Occurrence and role 482-21935 during chemical and biological evolution Cardiac output increase and gas exchange at start 482-20975 of exercise Could the biochemical metabolism be different 482-21936 482-20976 PIBIDOJIBE PSTCaOACOOSTICS Vitamin C, B sub 1 and B sub 6 excretion in urine Quantification of psychoacoustic tuning curve during 182-day antiorthostatic hypokinesia sharpness: An analysis of frequency resolution H82-17824 in children and adults PIBOLIXIC GBAPHITE N82-17857 Organic geochemistry of the Isua supracrustals Forward masking of auditory nerve (N sub 1) and 482-20961 brainstem responses (lave T) in humans B82-17860 PSYCHOLOGICAL EFFECTS Q Psychological problems in the mutual adaptation of Q04BTIT1TIVE ABALXSIS man and machine in control systems Bussian 4 model for essential hypertension: Metabolic book studies 482-19000 H82-17867 Particular features of conditioned QD48TDB BECH4HICS electrodefensive reflex in white rats on Quantum mechanical conformational analysis of background of constant magnetic field aminoacyladenylates - Implication in the origin H82-17851 of life PSYCHOLOGICAL F4CTOBS 482-20941 The use of linear models for EEC analysis 482-20326 PSYCHOLOGICAL TESIS Staying sane in space 482-19743

1-40 SOBJECT IHDEI BECEPTOBS (PHYSIOLOGY)

Characteristics of the relations of the primary responses of the pentose phosphate pathway to glycolysis in the bone marrow of irradiated rats B1BBITS A82-21725 Stationary magnetic fields and reticalar Changes in morphological and cytogenetic influences on adrenergic and cholinergic systems hematopoietic indicators in hamadryas baboons H82-16725 exposed to chronic low-level radiation BADIAIT BEiTIIG A82-21726 The thermal response of a human in the near-zone The effects of successive ionizing radiation and of a resonant thin-Hire antenna heat on antibody formation A82-22206 A82-21751 BADIAXIOB DOSA6E The effects of elevated environmental temperature The biological effects of low-level ionizing combined with radiation on the organism radiation A82-21752 A82-20146 Metabolic change in test animals as an indicator Changes in morphological and cytogenetic of the biological effect of an electromagnetic hematopoietic indicators in haaadryas baboons field having a frequency of 50 Hz exposed to chronic lov-level radiation A82-21758 A82-21726 The role of C02 in the mechanism of the reparative Genetic damage in Escherichia coli K12 AB2480 by regeneration of bone tissue /a radioisotopic broad-spectrum near-ultraviolet radiation study/ A82-22200 A82-21800 Clinical distinctions of radiation sickness with The thermal response of a human in the near-zone exposure of different parts of the human bod; to of a resonant thin-wire antenna radiation A82-22206 H82-16726 Current problems of radiobiology of BAOIATIOI EFFECTS electromagnetic radiation of radio-frequency range Absence of the additive effect in the combined H82-17850 irradiation of Crepis capillaris feeds and BADIOLISIS seedlings by gamma rays and neutrons The radiolysis and radioracemization of amino A82-21723 acids on silica surfaces Changes in morphological and cytogenetic A82-20019 hematopoietic indicators in haaadryas baboons BADIOHBSBBS exposed to chronic Ion-level radiation Badiometric determination of potassium content in A82-21726 athletes The effects of successive ionizing radiation and A82-21822 beat on antibody formation BABDOB BOISE A82-21751 Mathematical model of a human operator detecting a. USSB report: Life sciences effects cf nonionizing signal on a noise background electromagnetic radiaticn, no. 4 A82-21893 [JPBS-79780] H82-17844 BATES (PBB TIBE) BADIATIOB IHJuBIES Problems in the rate of evolution in biological Clinical distinctions of radiation sickness with systems exposure of different parts of the human bod; to A82-21989 radiation BA1S N82-16726 Positions, movements and equilibrium of rats after BADIAIIOI SICKHESS flights aboard biosatellites Some indicators of protein metabolisa in 1182-16713 erythrocytes during radiation sickness and Norepinephrine and enzymes of synthesis and following cystamine injection degradation thereof in the rat hypothalamus A82-21724 following flight aboard the Cosmos-936 The effects of elevated environmental temperature biosatellite combined with radiation on the organism N82-16716 . A82-21752 Succinate dehydrogenase and cytochrome oxidase Clinical distinctions of radiation sickness with activity in tissues of rats submitted to exposure of different parts of the human bod; to long-term hypokinesia radiation H82-16723 N82-16726 Lipid spectrum of the myocardium of white rats BADIATIOB IOLBBABCE exposed to hypoxic hypoxia Ultraviolet selection pressure in the Erephanerozoic N82-16724 ancient microorganism survival BBACTIOI KIHEIICS A82-20969 Bates of fixation by lightning of carbon and BAOICALS nitrogen in possible primitive atmospheres Asymmetrical radical formation in beta-irradiated A82-20016 D- and L-alanines BEACTIOS PBODDCTS A82-20949 The appearance of protobiopolymers and BADIO FBBflUBiCIES protomeubranes in accordance with the 'cold Current problems of radiotiology of theory* of the origins of life electromagnetic radiaticn of radio-frequency range A82-20936 H82-17850 BBBBBAIBI1G BADIOBI010GI Bate of uptake of carbon monoxide at different Measurement of radio frequency permittivity of inspired concentrations in humans biological tissues with an open-ended coaxial A82-21930 line. I BECEPIOBS (PHYSIOLOGY) A82-20891 Parameters of the interaction of bradykinin with Measurement of radio frequency permittivit; of cardiovascular system receptors biological tissues vith an open-ended coaxial A82-20332 line. II ' Experimental results Filtration properties of receptive fields of A82-20892 visual-cortex neurons Ultraviolet selection pressure in the Prephanerozoic A82-21470 -:— ancient microorganism survival Bhodopsin aggregation under the damaging effects A82-20969 of light on the photoreceptor membranes Absence of the additive effect in the combined A82-21705 irradiation of Crepis capillaris seeds and Functional characteristics of receptors connected seedlings by gamma rays and neutrons with sustaining the flight of the roach A82-21723 Periplaneta Americana L A82-21716 Types of spontaneous discharges in muscle receptors A82-21789

1-41 BBDOCTIOH (CHBHISTBI) SUBJECT IBDEX

BBDOCTIOB (CHBHISIBI) The use of oxygen as the test gas in the Organic chemical evolution of reducing model of determination of the closing volume of the atmosphere of the priaitive earth - Bole of respiratory ducts DV light and electric discharges A82-21801 482-20912 An asymmetrical model of the airways of the dog lung Fhotoassisted carbon dioxide reduction and 482-21926 formation of tuoand three-carbon compounds Phase ? of the single-breath washout test prebiological photosynthesis A82-21928 A82-20920 Pulmonary gas exchange during altered density gas Seduction of thionucleosides - 4 prebiotic pathway breathing to deoxyribonucleosides 482-21935 482-20928 Cardiac output increase and gas exchange at start BEFLBXBS of exercise Summated circulatory responses of thermal and 482-21936 baroreflezes in humans BESPIB4TOBI SISTEfl A82-21933 The state of the vegetative functions during sleep Electrode unit for testing human H reflex 482-21771 H82-16728 Bespiratory toxicology, 1981 BEGEIEBATIOH (PHYSIOLOGY) [4D-A107672] H82-17841 The source of reparative regeneration in skeletal BEST muscle tissue Natural resistance of the organisms of seamen 482-21768 during postcruise rest The role of CO2 in the mechanism of the reparative A82-20311 regeneration of bone tissue /a radioisotopic BE1ESTIOB (PSYCHOLOGY) study/ Ability differences and cognitive mapping skill 482-21800 [AD-4106389] B82-16741 Distinctions of regeneration of confined BBTIBAL IBAGES atmosphere by means of photosynthesis of Detection of amblyopia utilizing generated retinal unicellular algae reflexes H82-16720 [HAS4-CB-1619t'(] H82-16732 BBLAXATIOI (PHYSIOLOGY) BHEOEBCEEH4LOGBASHY The temperature dependence of the kinetics of Phasic energy analysis of rheoencephalograms in isometric myocardium relaxation the detection of the decompensation of cerebral 482-19718 hemodynamics The dynamics of muscular relaxation following 482-2175U unfused tetanuses of different durations BHEUH4TIC DISEASES 482-21707 4 study of tropomyosins in human muscular and Effect of calcium on the temporal characteristics nonmuscular organs of muscle contraction 482-21806 482-21708 BHITHfl (BIOLOGY) BE14L FOBCTIOB The effect of motor activity on the development of The effects of an aqueous potassium loading test cardiac arrhythmias in experimental emotional on kidney fnncticn stress 482-20329 482-21713 4 three-dimensional model for the arrangement of Disturbances in biological rhythms as a result of the vascular and tubular components of the renal a conflict of incompatible stimuli osmoregulatory apparatus 482-21720 482-217<»5 Seasonal rhythm of the immune reactivity and heart The role of urokinase in the regulation of the tolerance to physical load in patients with fibrinolytic activity of blood under normal ischemic heart disease conditions 482-21802 482-21799 Effect of transmeridional flights on biorhythm of BESPIB4TOBI DISEASES zone formation by Streptomyces levoris changes in microcirculatory flow with respiratory H82-16711 insufficiency Phenomena of fluctuation of human reaction to 482-20323 antiorthostatic position BESPIBATOBY PHYSIOLOGY H82-16721 Breath-by-breath measurement of true alveolar gas Cerebral hemispheric activity and antomonic exchange nervous function 482-19498 H82-17868 Physiology and pathology of respiration and means BIBOHDCLEIC ACIDS of correcting oxygen deficiencies in an organism Origin of translation - The hypothesis of /Meeting of the Interdepartmental Connission on pernanently attached adaptors proposed the Coordination of Studies in Medicine of the prebiotic amino acid synthesis Academy of Sciences of the Ukrainian SSB and the 482-20022 Ministry of Health of the Dkrainian SSB/ Origin and evolution of the genetic code 482-20303 482-20955 Special and clinical physiology of hypoxic states Evolutionary processes of the genetic code 482-20317 482-20957 A combined method for the study of tissue Primitive transfer BH4 and origin of Darwinian respiration under conditions corresponding to system natural gas homeostasis 482-20959 482-20321 Nucleic acid and protein metabolism in cardiac The significance of airflow resistance to changes muscle in responses to increasing hypercapnia 482-21772 482-20327 BIDIH6 QUALITY Bespiration of brain synaptosomes under conditions An evaluation of helicopter noise and vibration of depolarization in rats deprived of paradoxal ride qualities criteria sleep [NASA-TH-83251] H82-17871 482-20336 BOBOTS Pulmonary shunting and its regulation Biped walking - Model problems of dynamics and 482-21728 control The effect of blood pressure in the pulmonary 482-18977 artery on gas exchange in functionally Development of an integrated walking robot heterogeneous lungs 482-18988 482-21738 BOTATIOH Method of recording rotatory eye reflexes H82-16727

I-K2 SOBJECT IBDEZ SOLAB SZSTBB

BDIIIIG SEBOBS Erythrocyte indices daring a competitive marathon The effects of daily blood sampling on creatine 482-21932 phosphokinase, aspartate aminotransferase and alanine aminotransferase activities in the blood serum of the monkey 482-21811 SACCAOIC EIE BOVBBEBIS Blood serum nuclease activity in healthy persons Differences in eye movement data recorded by and patients with various hematological diseases electro-oculography and corneal reflection 482-21813 techniques SEZ FACMB 482-19224 The effect of two years' training of aerobic power Study of the electrical activity of the and muscle strength in male and female cadets extraocular muscles 482-21678 482-21731 Characteristics and patterns of the individual SAFETZ FACTOBS development of male and female rats in the light Evaluation of safety of decompression from the of the energy rule of skeletal muscles critical volume of gas cubbies formed in the 482-21721 organism SHIPS 482-21717 4 statistical examination of three approaches for Review of literature and regulation relating to predicting motion sickness incidence thoracic impact tolerance and injury criteria 482-21685 [PB82-108697] H82-16736 SHIVEBISG S4LI8ITT. Comparative neurophysiological characteristics of Hicrobial life in cold saline environments cold and caudate tremors 482-20974 482-21790 SALI01 SPACE STATIOI SIGHAL DBTECCIOH Status of space biomedical programs Mathematical model of a human operator detecting a H82-17239 signal on a noise background SATELLITE COMTBOL 482-21893 Human-machine interface issues in the SIGHAL EBOCBSSIBG flultisatellite Operations Control Center-1 Functional model of the conversion of stationary (HSOCC-1) signals in the auditory analyzer [NAS4-TH-83826] H82-17875 482-21703 SCHI20PHBEBIA The effects of microphones and facemasks on LPC The use of linear models for EEG analysis vocoder performance 482-20326 £40-4107908] B82-16744 SCHOOLS SIGHAL TO BOISE BATIOS Physiological-hygienic substantiation of Mathematical model of a human operator detecting a admissible noise level in school rcoms in a hot signal on a noise background climate A82-21893 482-21749 SILICOH DIOXIDE SEEDS The radiolysis and radioracemization of amino Absence of the additive effect in the combined acids on silica surfaces irradiation of Crepis capillaris seeds and 482-20019 seedlings by gamma rays and neutrons SIHE WAVES 482-21723 Acceleration measures and motion sickness incidence SELF ABSOBPTIOH [AD-A107996] H82-16734 Mechanises of cadmium absorption in rats SLEEP [PB82-108184] 882-16703 Electroencephalographic correlates of the SELF OBGABI2IIG SISIEBS differentiation between verbal stimuli during Coupling to solar energy: Sensitized natural night sleep in humans photoreactions - The primary source of 482-20315 self-organization Bespiration .of brain synaptosomes under conditions 482-20968 of depolarization in rats deprived of paradoxal SEMSITIVI1I sleep Quantification of psychoaconstic tuning curve A82-20336 sharpness: An analysis of freguency resolution The state of the vegetative functions during sleep in children and adults 482-21771 U82-17857 Emotions, sleep, and health SEHSOfllHOTOB fEBFOBBABCE 482-21804 The effect of the motor activity regime on the SLEEP DEPBIVAIIOH development, conservation, and regeneration of The dynamics of protein and nucleic acid content defensive conditioned reflexes in rats in rat raphe nucleus cells after total 482-20305 deprivation of sleep /in a rotating cylinder/ 4 systems analysis of human motor reactions in and selective deprivation of its paradoxical phase various modes of operation of goal-directed A82-21718 behavioral acts SOCIAL FACTORS 482-21729 The physical activity of humans as a social and Huscle, motor cortex, cerebellar nuclear, and biological problem spindle afferent during slow hold-ramp-hold A82-21760 position-tracking movements of the monkey's wrist SODIDB H82-17854 The role of natrinresis in the prophylactic effect SBHSOBZ FEEDBACK of adaptation to hypoxia in the case of The role of biofeedback in the adaptive regulation hereditary hypertension of pathological bioelectric brain activity 482-21712 482-20328 SODIOB COBPOOHDS SEHSOBZ SIIHOLATIOB Possible selective adsorption of enantiomers by Disturbances in biological rhythms as a result of Ha-montmorillonite a conflict of incompatible stimuli 482-20946 482-21720 SOLAB BHEBGI COBVBBSIOB 4 systems analysis of human motor reactions in Coupling to solar energy: Sensitized various modes of operation of goal-directed photoreactions - The primary source of behavioral acts self-organization 482-21729 A82-20968 SOLAB SISTB8 Are comets connected to the origin of life A82-20865

1-43 SOLID BLBCIBODES SUBJECT IBDEI

SOLID ELBCfBODBS Activity of some enzymes of carbonhydrate Amino acids derivatives synthesis from nitrogen, metabolism in rat skeletal muscles after space carbon and water by electric discharges flight £82-20018 B82-17834 SOOHO LOCALIZATION SPACECBEIS Auditor; depth perception - Localization of working in space Book nonnoviog and moving sound sources A82-20772 A82-21727 SPBCTBAL BBFLECTAHCE SOOBD TfiABSfllSSIOB Organic and inorganic interpretations of the Characteristics of the structure and functions of flartian DV-IE reflectance spectrum the niddle ear of lizards A82-21208 A82-21823 SPBCTBAL SBBSITIVIXZ SOOBD BAVBS Psychophysical evidence for more than two kinds of Forward masking of auditor; nerve (H sub 1) and cone in dichromatic color blindness brainsteo responses (lave T) in humans A82-19608 H82-17860 SPEECH BECOGMITIOl SOIOZ SPACECBAFI The effects of microphones and facemasks on LPC Status of space biomedical programs vocoder performance H82-17239 {AD-A107908] B82-16744 SPACE SPBBBATOZOA Borepinephrine and enzymes of synthesis and Possible uecbanism for chemical induction of degradation thereof in the rat hypothalamus chromosome aberrations in male meiotic and following flight aboard the Cosmos-936 postmeiotic germ cells of mice biosatellite [DE81-031999] B82-16700 H82-16716 SPIRAL COED SPACE FLIGHT Investigation of recurrent inhibition in the human Hygienic principles of ongoing monitoring of spinal cord daring static skeletal muscle activity gualit; of recycled water during space flights A82-20330 H82-16717 Features of the reaction to noise of the spinal SPACE FLIGHT fBBDIHG capillaries of white rats Diet of crews of three main expeditions aboard A82-21767 Salyut-6 orbital station Electrode unit for testing human B reflex H82-17815 N82-16728 Amino acid metabolism during prolonged intake of STAHDABDS dehydrated foods and simulation of some space Health effects of carbon monoxide and ozone flight factors [PB82-114265] B82-17866 1182-17816 STAPHILOCOCCDS SPACE FLIGHT STBBSS Prevention of staphylococcal infections during Staying sane in space space flights A82-19743 H82-17818 USSB report: Space biology and aerospace STATIC LOADS medicine, vol. 15, no. 5, Sep. - Oct. 1981 Investigation of recurrent inhibition in the human £JPBS-79346] N82-17812 spinal cord during static skeletal muscle activity Effect of space flights of different duration on A82-20330 energ; metabolism of human erythrocytes STATISTICAL ABALISIS N82-17817 Evaluation of maximal and submaximal static muscle Human lipid netabclism during confinement in exertions pressure chamber A82-19223 H82-17822 STEBEOCBEBISTBI Oltrastructure of blood vessels and muscle fibers Besolution of underivatized amino acids b; high of rat skeletal muscles after flights aboard pressure liguid chromatography. using chiral Cosmos-605 and Cosmos-782 biosatellites elnants H82-17835 A82-20944 Blood fibrinogen as related to immersion in water Stereoselective interactions of small biological for seven days and short-term space flight molecules B82-17836 A82-20945 SPACE FLIGHT TBAIHIS6 STOCHASTIC CBOCESSBS Staying sane in space A neutral theor; of biogenesis A82-19743 A82-20024 SPACE HAHUFACTOHIHG STOBA6E STABILITY If or king in space Book Storage stability and improvement of intermediate A82-20772 moisture foods, phase 5 SPACE PEBCEPTIOS [BASA-CB-167503] N82-16742 Auditory depth perception - Localization of Comparative evaluation of antimicrobial activit; nonmoving and moving sound sources of some urine preservatives A82-21727 H82-17830 SPACE PBOGBAHS STBEPTOHICEIES Status of space biomedical programs Effect of transmeridional flights on biorh;tho of H82-17239 zone formation b; Streptomvces levoris SPACE SOUS H82-16711 Survival in space spacesuit development STBESS (BIOLOGI) A82-20257 Disturbances in biological rhythms as a result of Ways and means of maintaining heat balance in a conflict of incompatible stimuli pilots and cosmonauts A82-21720 M82-16706 The effect of cold stress on the level and SPACEBOBIE BXPEEIBEHTS activity of microsomal cytochrome P-450 in the Positions, movements and equilibrium of rats after rat liver flights aboard biosatellites A82-21732 B82-16713 Emotional stress as a factor in cardiovascular Bat a mino acid composition after flight aboard disorders Cosmos-1129 biosatellite A82-21796 H82-17831 STBESS (PHISIOLOGZ) Hyocardial protein fractions and enzymatic Glycogen and nonspecific adaptation to cold activity thereof in eiperimental rats flown A82-19494 aboard Cosmos-936 biosatellite The influence of adaptation on the periodic effect H82-17832 of hypoxia on the poststress activation of the Metabolic processis in rat skeletal muscles after primary immune response flight aboard Cosmos-S36 A82-20320 H82-17833

1-44 SUBJECT I1DBI SIBIHESIS (CHBBISIBI)

Hicrocirculation, tolerance to physical strain, Acute experimental emotional stress in rabbits and certain homeostasis parameters in patients /physiological and cytochemical aspects/ Kith angina pectoris 482-21825 482-20321 STODEHSS Functional condition of the rat sympato-adrenal The effect of two years' training of aerobic power system daring emotional and nociceptive stress and muscle strength in male and female cadets 482-20335 482-21678 The effect of motor activity on the developBent of Development of an automatic data bank for managing cardiac arrhythmias in eiperimental emotional physical education of students stress 482-21816 182-21713 SOG4BS Activation of the metabolism of the Genesis of anino acids in the primeval sea - gaoina-amiuobutyric acid system in the cerebral Formation of anino acids from sugars and ammonia hemispheres under various types of stress in a modified sea medium 482-21746 482-20925 Echoencephalcgraphic indices in patients with SOBF4CI4BTS hypertensive disease under the effect of Air embolism - Possible role of surfactant on functional loads recompression 482-21753 482-21931 Changes in the structure and cellular composition SOBGBBY of the inguinal lymph nodes of white rats The possibility of using mathematical methods for subjected to static and dynamic stresses predicting the results of the surgical treatment 482-21761 of patients with vasorenal hypertension Heuronal-glial alterations in the cerebral cortex 482-21709 of animals under the influence of white noise SOSPESDIBG (BIIIBG) 482-21769 Changes of the aggregation and orientation Lysosomes under conditions of stress structure of blood in pulsating flow 482-21770 482-20333 The effect of the prolonged administration of SBE4I sodium hydroxybutyrate on the physical work Effect of blood volume on sweating rate and body capacity and muscle tissue state of rats fluids in exercising humans 482-21779 482-19495 Adaptogenic effect of mebicar during emotional SBIHHIBG stress, exercise, and hypoxia Predicting the potentials of young swimmers based 482-21780 on clinical and physiological data The ultrastructure of the liver sinusoids of nice 482-21814 under conditions of acute stress - Horphometric SYMBIOSIS study The evolution of blue-greens and the origins of 482-21782 chloroplast's The dynamics and physiological importance of the 482-20971 activation of the gasma-amino—butvric acid Evolution of the rhodospirillaceae and system in the brain and cardiac auscle under mitochondria - 4 view based on sequence data pain and emotional stress 482-20972 482-21808 SYHP4THETIC BEBVOOS SYSTEH Mechanisms of adaptation to ergothermic hypoxemia Functional condition of the rat sympato-adrenal in athletes specializing in different sp.orts system during emotional and nociceptive stress 482-21820 482-20335 Stress and immunity in athletes The myenteric plexus - Basic principles of 482-21821 modeling neuronal organization Fatigue in Flight Inspection Field Office (FIFO) 482-20337 flight crews Human adrenosympathetic system during immersion in [4D-4106791] S82-16733 water STBESS (PSYCHOLOGY.) B82-17819 Staying sane in space SYH4PSES 482-197113 The effect of synaptically active drugs on the Acute experimental emotional stress in rabbits in hyperthernic effect of prostaglandin E2 in rats a modulated electromagnetic field 482-21741 482-20307 SIBCHBOBISH The influence of adaptation on the periodic effect The effects of emotional activation on the spatial of hypoxia on the poststress activation of the synchronization of human brain biopotentials primary immune response 482-21785 482-20320 SIBCOPB Contractile dysfunction of vascular wall smooth Orthostatic fluid-electrolyte and endocrine muscle under emotional ncciceptive stress responses in fainters and nonfainters 482-20322 482-191(92 Functional condition of the rat sympato-adrenal SYBTHESIS (CHBSISTBI) system during emotional and nociceptive stress Abiotic organic synthesis in space 482-20335 482-20910 Change in the nature of the psychotropic effect on Formation of prebiotic precursors from model the emotional reactivity and behavior in stress reducing atmospheres Bole of hydrogen escape situations depending on the state of the 482-20911 catecholaminergic systems of the brain The Strecker synthesis in the primitive ocean 482-21739 chemical evolution Activation of the metabolism of the 482-20919 gamma-amiuobutyric acid system in the cerebral Belanoidin polymers as possible oxygen sinks in hemispheres under various types of stress the pre-biotic oceans 482-21746 482-20921 Adaptogenic effect of mebicar during emotional Abiotic synthesis of phosphoric esters of stress, exercise, and hypoxia monosaccharides according to the 'cold model* 482-21780 482-20923 BEG evaluation of mental stress Porphyrin-like compounds genesis under simulated 482-21784 abiotic conditions Emotions, sleep, and health 482-20S26 482-21804 HCH oligomerization - Isolation and preliminary The dynamics and physiological importance of the characterization of a new precursor of adenine activation of the gamma-amino-butyric acid 482-20930 system in the brain and cardiac muscle under pain and emotional stress 482-21808

1-45 SISfEHS I1TBGBAIIOB SOBJECT liDEX

Selective acylability of amino acids by TBEBSISTOBS non-enzymic model reactions of biocheoical Portable medical status and treatment system transacylations [HASA-CE-167496] H82-17862 A82-20965 TflBBHOCBBBISIBT SYSIEHS IHIEGBA1IOB Bates of fixation by lightning of carbon and Development of an integrated walking robot nitrogen in possible primitive atmospheres A82-18988 A82-20016 SISTEHS SIHOLATIOS THEBHODIBABIC CODPLIHG Conpater simulation as a visual aid in a video Coupling to solar energy: Sensitized coarse for ATC system performance photoreactions. - The primary source of £82-19248 self-organization A82-20968 THEBaOBBGOLATIOB Enhanced heat production in physically restrained TASKS rats in hypoxia Pilot workload: A survey of operational problems A82-19496 [AD-A1Q7758] N82-16745 The influence of muscular work on the vestigial TECBIOLOGICAL FOBECASIJBG effects of cold acclimation Visaal technology and the future for flight A82-19749 simulators Body temperature changes during the practice of g A82-20538 Tun-mo yoga IBCTOHICS A82-21213 Chemical evolution and plate tectonics The effect of synaptically active drugs on the A82-20918 hyperthermic effect of prostaglandin E2 in rats IE8PEBAIDBE DEPEBDBBCE A82-21741 The temperature dependence of the kinetics of Hays and means of maintaining heat balance in isooetric myocardium relaxation pilots and cosmonauts A82-19748 H82-16706 Temperature dependence of alanine and aspartate THIAHIBE aminotransferase activities in rat brain during Vitamin C, B sub 1 and B sub 6 excretion in urine hypothermia of various durations and adrenalectomy during 182-day antiorthostatic hypokinesia 482-21812 N82-17824 TEHPBBATOBE EFFECTS THOBAI dicrobial life in cold saline environments First aid for thorax traumas: Thorax drainage A82-20974 through suction - Beport on 25 cases The effect of cold stress on the level and 182-19016 activity of microsomal cytochrome P-450 in the Beviev of literature and regulation relating to rat liver thoracic impact tolerance and injury criteria A82-21732 [PB82-1086S7] 1182-16736 The effect of low temperature on the activity and TBBESBOLDS (PBBCBPTIOH) substrate specificity of aonoamine ozidases in Temporal integration of acoustic power for rat brain mitochondria interrupted stimuli at suprathreshold levels A82-21735 H82-17856 Effect of low-temperature on the membrane THIBOS G1ASD permeability of erythrocjtes reconstituted in Clinical results on thyoectomy in patients with media of different icnic composition myopathy in relation to the degree of muscular A82-21737 weakness The effects of elevated environmental temperature A82-21755 combined with radiation on the organism TIHE LAG A82-21752 Effect of calcium on the temporal characteristics Mechanisms of adaptation to ergothermic hypoxemia of muscle contraction in athletes specializing in different sports A82-21708 A82-21820 TISSUES (BIOLOGY) Effects of temperature on the duration of arousal The measurement of oxygen and carbon dioxide episodes during hibernation partial pressures in tissues by the gas depot A82-21934 method TEHP1ATES A82-20318 Origin of translation - The hypothesis of A combined method for the study of tissue permanently attached adaptors proposed respiration under conditions corresponding to prebiotic aaino acid synthesis natural gas homeostasis A82-20022 A82-20321 Search for primitive replicative properties on Measurement of radio freguency permittivity of early polypeptides biological tissues with an open-ended coaxial A82-20963 line. I TBBBBSTBIAL PLABBTS A82-20891 Evolution of the terrestrial atmosphere and its Measurement of radio freguency permittivity of fossils in biosystems biological tissues with an open-ended coaxial A82-20960 line. II - Experimental results TESTES A82-20892 Effect of comaercial freguency electromagnetic A mathematical model of cell populations with stem field on androgen function of rat tests cells H82-17845 A82-21702 THA1AHDS Evaluation of safety of decompression from the The structural and functional organization of the critical volume of gas bubbles formed in the ventrolateral nucleus of the thalamus organism A82-21455 Ad2-21717 THEBAPI Age morphofnnctional characteristics of chromaffin physiology and pathology of respiration and means tissue in the celiac nodes, both in the norm and of correcting oxygen deficiencies in an organism with hypokinesia /Meeting of the Interdepartmental Commission on A82-21766 the Coordination of Studies in Medicine of the The source of reparative regeneration in skeletal Academy of Sciences of the Ukrainian SSB and the muscle tissue Ministry of Health of the Ukrainian SSB/ A82-21768 A82-20303 The role of C02 in the mechanism of the reparative THEBHAt ABSOBPTIOB regeneration of bone tissue /a radioisotopic The thermal response of a human in the near-zone study/ of a resonant thin-wire antenna A82-21800 A82-22206

1-46 SUBJECT IBDBX VASCULAB SISTEfl

Saccinate dehydrogenase and cytochrome oxidase TBABSPOBT PBOPEBTIBS activity in tissues of rats submitted to Some mechanisms of calcium transport by the long-term hypokinesia cardiac sarcolemma B82-16723 B82-17810 Ultrastructure of blood vessels and muscle fibers TBEADHILLS of rat skeletal muscles after flights aboard A stud; of treadmill exercise protocols for Cosmos-605 and Cosmos-782 biosatellites Chinese males H82-17835 A82-21677 Biophysical fundamentals and instrumentation for TBBHOBS the ecdovesical Nd:!AG-laser application Comparative neurophysiological characteristics of tumor therapy cold and caudate tremors [MBB-UA-581-81-0] 882-17843 A82-21790 TITHAII01 TBOPICAL BEGIOBS Potentiometric titration behavior ,of polyamino Laws governing readaptation for seamen after a acids prepared by thermal polycondeusation low-latitude cruise A82-20938 A82-20310 TOLBBAICBS (PHISIOLOGI) Physiological-hygienic substantiation of Antihypoxic efficacy of intermittent mode of admissible noise level in school rooms in a hot pressure chamber conditioning of man climate H82-17827 A82-21749 TOXIC HAZABDS TOHOBS Respiratory toxicology, 1981 Biophysical fundamentals and instrumentation for [AD-A107672] B82-17841 the endovesical Nd:lAG-laser application Health effects of carbon monoxide and ozone tumor therapy [PB82-114265] B82-17866 [HBB-DA-581-81-0] B82-17813 TOUCH! TOBIHG Mammalian toxicological evaluation of OIHP and Peculiarities of the middle ear structure in DCPD (Phase 3 - IB PA) rodents as an index of the frequency tuning of £AD-A107574] B82-17840 their auditory system Comparative biochemistry and metabolism. Part 2: A82-21714 Naphthalene lung toxicity Quantification of psychoacoustic tuning curve [AD-A107673] S82-17842 sharpness: An analysis of frequency resolution Comparative biochemistry and metabolism. Part 1: in children and adults Carcinogenesis B82-17857 [AD-A107614] H82-17865 TOXICOLOGI Summary of a discussion on the problem of the u 'biological norm' /in relation to an assessment D.S.S.B. of criteria of the harmfnlness of chemical Status of space biomedical programs effects/ B82-17239 A82-21750 OLTBASOHIC TES1S Toxicological and hygienic aspects of improving Informativeness of ultrasonic Doppier cardiograph? additional purification of water reclaimed from in evaluation of coronary circulation urine B82-17828 H82-16718 OLTBAVIOLET BADIATIOB Sespiratory toxicology, 1981 Organic chemical evolution of reducing model of [AD-A107672] B82-17841 the atmosphere of the primitive earth - Bole of TRACE BLEBB1TS UV light and electric discharges Differentiation of muscles on the basis of A82-20912 trace-element composition Ultraviolet selection, pressure in the Prephanerozoic A82-21704 ancient microorganism survival XBACKIIG (POSITIOB) 482-20969 Huscle, motor cortex, cerebellar nuclear, and OLTBAVIOLET SPECIBA spindle afferent during slow hold-ramp-hold Organic and inorganic interpretations of the position-tracking movements of the monkey's wrist Martian DV-IB reflectance spectrum B82-17854 A82-21208 TBAIIIIG ABALISIS DBSTEADY FLOi Development of the Automated Performance Changes of the aggregation and orientation Assessment and Benedial Training System structure of blood in pulsating flow (APABTS): A landing signal officer training aid A82-20333 [AD-A106224] B82-17873 OBEAS DOT/FAA Human Factors workshop on Aviation. Increased excretion of urea and Transcript, volume 2 B/tau/-methylhistidine by rats and humans after [AD-A107803] B82-17877 a bout of exercise TEAJIIBG DEVICES A82-21927 The semi-automatic instructional system of OBIHB B-52 weapon system trainers Toxicological and hygienic aspects of improving A82-20539 additional purification of water reclaimed from Development of the Automated Performance urine Assessment and Bemedial Training System B82-16718 (APABTS): A landing signal officer training aid Comparative evaluation of antimicrobial activity £AD-A106224] H82-17873 of some urine preservatives TBAIBI1G EVALUAIIOB 882-17830 Development of the Automated Performance Assessment and Bemedial Training System (APABTS): A landing signal officer training aid [AD-A106224] S82-17873 V/ST01 AIBCBAFT IBAIBIBS SIBOLAIOBS VTOL/STOL visual study Advanced aviation concepts evaluation through [MASA-CB-166292] H82-17872 computer driven simulation human factors VAB DE 6BAAFF ACCELBBATOBS consideration in flight training simulator design Asymmetrical radical formation in beta-irradiated A82-19258 D- and L-alanines Visual technology and the future for flight A82-20949 simulators VASCOLAB SYSTEB A82-20538 Contractile dysfunction of vascular wall smooth Development of the Automated Performance muscle under emotional nociceptive stress Assessment and Bemedial training System A82-20322 (APABTS): A landing signal officer training aid [AD-A106224] 1182-17873

1-47 VELOCITY HEASOBEHBHT SUBJECT liDEI

VELOCITY HEASDBEHEHT Difference between eye closure and visual In vivo recording of blood velocity profiles and stabilization in the control of posture in man studies in vitro of profile alterations induced A82-21686 by known stenoses Boise and vibration effects on vestibular and [PB81-244139] H82-16738 visual functions in teenagers VEBBAl COHHOBIC4TI08 A82-21747 Electroencephalographic correlates of the Coordination of processes in the hierarchic differentiation between verbal stinuli during structure of the visual analyzer natural night sleep in humans A82-21788 A82-20315 VISOAL STIHOLI VEBTICAL HOTIOH SIHOLATOBS Frequency characteristics of visual evoked VTOL/STOL visual study potentials in different regions of the human [HASA-CB-166292] 882-17872 cerebral cortex VEBTIGO A82-20314 Posturography of ataxi a induced by Coriolis- and VISOAL TASKS Purkinje-effects Differences in eye movement data recorded by A82-21684 electro-oculography and corneal reflection VESTIBOLAB BYSTAGHOS technignes The functional condition of the ampullar apparatus A82-19224 in Heniere's disease EE6 evaluation of mental stress A82-20308 A82-21784 Method of recording rotatory eye reflexes VITAHIHS N82-16727 Particular features of conditioned VESTIBOLAfi TESTS electrodefensive reflex in white rats on Vestibular responses of neurons in the feline background of constant magnetic field anterior suprasylvian gjrus and their N82-17851 interaction vith responses to acoustic and VOCODEBS facial stiauli The effects of microphones and facemasks on LPC A82-20309 vocoder performance Posturography of atazia induced by Coriolis- and [AD-A107908] N82-16744 Parkinje-effects VOLCABOBS A82-21684 Bew data on abiogenic synthesis of prebiological Noise and vibration effects on vestitular and compounds in volcanic processes visual functions in teenagers A82-20017 A82-21747 VOLDHB Method of recording rotatory eye reflexes .The use of oxygen as the test gas in the N82-16727 determination of the closing volume of VESTIBULES respiratory ducts Investigation of the otolithic membrane of the A82-21801 utricle of the guinea pig A82-20301 Trial on the use of stabilography in the medical w supervision of boxers BALKIBG HACHIBES A82-21817 Biped walking - Model problems of dynamics and Effect of the functional properties of the control vestibular analyzer on the effectiveness of 482-18977 instruction in gymnastics Development of aa integrated walking robot A82-21819 A82-18988 VIBBATIO1 BASIS DISPOSAL An evaluation of helicopter noise and vibration Possible use of house fly larvae for utilization ride gualities criteria of organic waste in biological life-support [.BASA-TH-83251] N82-17871 systems VIBBATIOB EFFECTS N82-16719 The reliability of flight personnel during the IATEB operation of the Mi-4 helicopter Liquid water on a planet over cosmic periods A82-19014 A82-20907 Functional characteristics of receptors connected Hicrobiologically-mediated mutagenic activity of vith sustaining the flight of the loach crude oil Periplaneta Americana L [PB82-105131] H82-16702 A82-21716 IATEB QUALITY Noise and vibration effects on vestitular and Hygienic principles of ongoing monitoring of visual functions in teenagers guality of recycled water during space flights A82-21747 H82-16717 Physiological and hygienic evaluation of vibration Toxicological and hygienic aspects of improving in the cockpit of a cargo helicopter additional purification of water reclaimed from H82-16709 urine VIBOSES H82-16718 The mathematics of immunity response to viral IAIEB BECLABATIOB intrusion Toxicological and hygienic aspects of improving A82-21824 additional purification of water reclaimed from VISIOI urine Detection of amblyopia utilizing generated retinal N82-16718 reflexes iAVBGOIDES [NASA-CB-16194U] H82-16732 Waveguide technique for the calibration of VISUAL ACUITY miniature implantable electric-field probes for The prevalence of visual deficiencies among 1979 use in microwave-bioeffects studies general aviation accident airmen A82-20893 A82-21688 iEAPOB SYSTEHS VISUAL AIDS The semi-automatic instructional system of Computer simulation as a visual aid in a video B-52 weapon system trainers course for ATC systen performance A82-20539 A82-19248 iBIGHTLBSSBBSS VISDAL DISCBIHIIATIOB Cathepsin activity of skeletal muscle and VTOL/STOL visual study myocardia myofibrils after exposure to [HASA-CB-166292] N82-17872 weightlessness and accelerations VISDAL PEBCEPTIOB B82-16714 Filtration properties of receptive fields of Cytokinetic evaluation of erythropoiesis during visual-cortex neurons long-term orbital flights A82-21470 H82-16715

1-48 SUBJECT I1DEI ZIHC

Status of space biomedical prograas VXCBIOH ISOIOPBS H82-17239 Asymmetrical radical formation in beta-irradiated iBIGBIlBSSIBSS SIHULAIIOH 0- and L-alanines The effects of horizontal body casting on blood 482-20949 volume, drag responsiveness, and *6z tolerance in the rhesus monkey A82-21682 Combined effect of simulated weightlessness and ZIHC accelerations on energy metabolism enzymes Hechanisms of cadmium absorption in rats H82-17820 [PB82-108181] H82-16703 9BI1S BOISE Heuronal-glial alterations in the cerebral cortex of animals under the influence of white noise 482-21769 & study of the acoustic reflex as elicited by selected environmental noise stimuli N82-17858 iOBK CAEACIXI Evaluation of maximal and submaximal static muscle exertions 482-19223 BEG description algorithm for use in clinical practice and studies of work capacity 482-20304 Functional condition and work capacity under mountain conditions 482-20313 Working in space Book 482-20772 The effect of the prolonged administration of sodium hydroxybutyrate on the physical work capacity and muscle tissue state of rats 482-21779 BEG evaluation of mental stress 482-21784 Evaluation of the functional state of the cardiovascular system in patients vita ischeoic heart disease vith reference to the nature of their occupational activity 482-21803 Physical health of truck drivers in the open-pit mining industry of the far north 482-21805 •OBK-BES1 CICLE Complex physiological-hygienic characteristics of a new work-rest regime for seamen 482-21748 iOBKLOADS (PSICHOPBTSIOIOGI) Psychological problems in the mutual adaptation of man and machine in control systems Eussian book 482-19000 Pulse rate evaluation of the relative physiological intensity of aerobic muscular work 482-20331 EEG evaluation of mental stress 482-21784 4 program for assessing pilot mental state in flight simulators [4144 PAPEE 82-0257] 482-22078 Pilot workload: A survey of operational problems [AD-4107758] N82-16745 iODHD HBiilHG Dynamics of the condition cf granulation tissue after injuries sustained at different times of the day 482-21763 •BIST Muscle, motor cortex, cerebellar nuclear, and spindle afferent during slow hold-ramp-hold position-tracking movements of the monkey's wrist 882-17854

BAT. FLOOBESCEHCE Differentiation of muscles on the basis of trace-element composition 482-21704

YOUTH Investigation and evaluation of cardiac arrhythmias in healthy young persons 482-21710 Predicting the potentials of young swimmers based on clinical and physiological data 482-21814

1-49 PERSONAL AUTHOR INDEX AEROSPACE MEDICINE AND BIOLOGYM Continuing Bibliography (Suppl. 232) MAY 1982

Typical Personal Author Index Listing

PERSONAL AUTHOR Current problems of radiobiology of electromagnetic radiation of radio-frequency range N82-17850 ALAIIBEV, V. I. YEGOBOV, I. A. Investigation of recurrent inhibition in the human — Cyclic nucleotides in tissues daring long-term spinal cord during static skeletal muscle activity hypokinesia A82-20330 [NASA-TH-76726] N82-11757 ALBKHIHA, B. H. Changes in microcirculatory flow Hith respiratory I insufficiency REPORT A82-20323 TITLE NUMBER ALEKSABDBOV, 0. V. Changes in microcirculatory flow with respiratory insufficiency The title of the document is used to provide the user with a brief description A82-20323 of the subject matter. The NASA or AIAA accession number is included in ALEKSEET, ?. H. each entry to assist the user in locating the abstact in the abstract section Pulse rate evaluation of the relative of this supplement. If applicable, a report number is also included as an physiological intensity of aerobic muscular work aid in identifying the document. A82-20331 The dynamics of heart rate recovery following work of various aerobic intensities A82-21815 ALFBBOTi, I. V. Besults of study of hemodynamics and phase ABELL, P. I. structure of the cardiac cycle during functional Comets and the origin of life - The stable isotope test with lower body negative pressure during approach 110-day Salyut-6 station flight A82-20864 H82-16722 ABBABOVA, 6. fl. ALIEVSKAIA, L. L. Clinical distinctions of radiation sickness with Effect of calcium on the temporal characteristics exposure of different parts of the human bod; to of muscle contraction radiation A82-21708 S82-16726 ALTMAH, IA. A. AIDAEALIEf, A. A. Auditory depth perception - Localization of Adaptation to high-altitude hypoxia at different uonmoving and moving sound sources ambient temperatures /before and during A82-21727 adaptation/ AL1THISHEV, A. A. A82-21715 Adaptation to high-altitude hypoxia at different AIVAZOVA. 0. KB. ambient temperatures /before and during The effects of successive ionizing radiation and adaptation/ heat on antibody formation A82-21715 A82-21751 A11IS, K. B. AIZBAI, B. I. Clay-mediated reactions of HCH oligomers - The The effects of an aqueous potassium loading test effect of the oxidation state of the clay on kidney function A82-20917 A82-20329 AHAHIBSCD, C. AJEL10. J. fl. Porphyrin-like compounds genesis under simulated Organic and inorganic interpretations of the abiotic conditions Martian OV-IB reflectance spectrum A82-20926 A82-21208 ASDBBE*. ID. ?. AKABOSHI, B. The use of oxygen as the test gas in the Asymmetrical radical formation in beta-irradiated determination of the closing volume of 0- and L-alanines respiratory ducts A82-20949 A82-21801 AKHALAIA, H. IA. AHDBEBVA, 0. S. The effect of cold stress on the level and Evaluation of the functional state of the activity of microsomal cjtochrcme P-150 in the cardiovascular system in patients with ischemic rat liver heart disease with reference to the nature of A82-21732 their occupational activity AKHHADIIEVA. A. K. A82-21803 Effect of transmeridional flights on biorhythm of AHIKBBVA. S. P. zone formation by Streptomyces levoris Nonesterified fatty acid metabolism during N82-16711 exercise in humans AKHVBBDXAB, L. A. A82-21809 Sociality in acute myocardial Infarction as ABIKIH. V. f. function of geomagnetic field activity in Yerevan Hicrocirculation, tolerance to physical strain, N82-17852 and certain homeostasis parameters in patients AKIHOf, V. I. with angina pectoris Cochlear analysis of sound intensity and some A82-20324 mechanisms of auditory sensations AHISIBOV, H. H. A82-21792 The influence of some triterpenic glycosides on AKOIEV, I. 6. C-14-alanine inclusion into the bone-marrow Effect of transmeridional flights on biorhythm of cells of rats zone formation by Streptcnyces levoris A82-20306 N82-16711

1-51 AllOFTB*, I. I. PBBSOBAL AUTHOR IB DEI

&BTDFTE». I. I. BABBABASH. B. A. Systemic and cerebral hemodynamics in flight The role of natriuresis in the prophylactic effect personnel exposed to moderate hypoxia of adaptation to hypoxia in the case of H82-16707 hereditary hypertension AB4PO?. A. 0. A82-21712 Effect of coding of the rhythmo-inotropic ratio BABEB. A. S. in a pathologically altered myocardium Rays and means of maintaining heat balance in A82-217UO pilots and cosmonauts ABBFOLOV, T. A. H82-16706 The effect of the prolonged administration of BABU.IA8, I. £. sodiun hvdroxybutyrate on the physical work Effects of dioxalim and oxamide on saccinate and capacity and muscle tissue state of rats lactate dehydrogenase activities in rat liver, A82-21779 kidney and brain tissues and on the chromosomal ABOBS. B. K. apparatus of bone marrow cells Electroencephalographic correlates of the 482-21778 differentiation between verbal stimuli during BABBABAS, J. natural night sleep in humans Phylogenetic sequence of metabolic pathways in A82-20315 Pcecasbrian cellular life ABSBAVSKII, I. A. A82-20967 Characteristics and patterns of the individual BABBBS, C. D. development of male and feoale rats in the light Alterations in responses to drugs of atria from of the energy rule of skeletal muscles white rats acclimated to hypobaric hypoxia A82-21721 A82-19U97 ABSLAIOV4, B. H. BABBBI, J. A. Effects of embient parameters on man Summated circulatory responses of thermal and H82-17826 baroreflexes in humans ABTIUKBIBA. B. I. 482-21933 Heuronal-glial alterations in the cerebral cortex BABBOi, B. B. of animals under the influence of white noise Air embolism - Possible role of surfactant on A82-21769 recompression • AIHBX, T. H. 482-21931 Heasurement of radio frequency permittivity of BABSOKOV, B. P. biological tissues with an open-ended coaxial Effects of dioxalim and oxamide on succinate and line. I lactate dehydrogenase activities in rat liver, 482-20891 kidney and brain tissues and on the chromosomal Measurement of radio frequency permittivity of apparatus of bone marrow cells biological tissues with an open-ended coaxial A82-21778 line. II - Experimental results BASSIHI, B. A82-20892 In vivo recording of blood velocity profiles and AOGOS3SSOB, T. B. studies in vitro of profile alterations induced Comets and the photochemistry of the paleoatmosphere by known stenoses 482-20866 {PB81-211139] H82-16738 AOBIAB-BLAJEBI, B. BAIOBV, A. S, Photoassisted carbon dioxide reduction and The structural and functional organization of the formation cf tvoand three-carbon compounds ventrolateral nucleus of the thalamus 482-20920 482-21155 AIZIKOV, G. S. BAZBAIOV, B. O. Positions, movements and equilibrium of rats after The effect of cholinomimetics on the development flights aboard biosatellites of hypothermia H82-16713 482-21781 AZIH, A. L. BAZILIOK, 0. V. The role of extracellular 02 and C02 tensions in Contractile dysfunction of vascular wall smooth membrane mechanisms of cerebral arterial smooth muscle under emotional nociceptive stress muscle regulation 482-20322 A82-197H7 BEAVBB, B. I. Breath-by-breath measurement of true alveolar gas exchange B 482-19498 BAGDAIBV, V. B. BEDBBBKO, ?. S. The use of oxygen as the test gas in the Cardiac output and cardiac cycle phase structure determination of the closing volume of of pilots during flights respiratory ducts H82-17821 482-21801 Informativeness of ultrasonic Doppler cardiography BAIOBOV, 1. I A. in evaluation of coronary circulation Hodels of a functional lapse in one hemisphere and H82-17828 of the nenropharmocological effects on the deep BBKEIO?, A. I. structures of the brain Effects of dioxalim and oxamide on succinate and 482-20325 lactate dehydrogenase activities in rat liver, BAtSB?ICB, V. K. kidney and brain tissues and on the chromosomal The physical activity of humans as a social and apparatus of bone narrow cells biological problem A82-21778 482-21760 BESB1EBEVA, H. P. BAITSCHBFFSKI, B. The healthy and the diseased human brain Secondary structures of polypeptides as 482-18872 evolutionary growing points BELEISKII, V. V. 482-20962 Biped walking - Hodel problems of dynamics and BA1IKIH. H. V. control Oxygen transport in dogs native to high altitudes 482-18977 during exercise BBLITSKAIA, B. A. A82-21719 Hetabolic processis in rat skeletal muscles after BAS-BDB, A. flight aboard Cosmos-936 Could life have evolved in cometary nuclei N82-17833 482-20025 BBLKABIIA, 6. S. BABABIDZE, D. fi. Question of redistribution of blood in orthostatic 4 histochemical investigation of the microvascnlar position effectors regulating the supply of blood to the H82-16705 cerebral cortex A82-2174H

1-52 EBBSOBAL iOTBOB IHDBX BBABDT, T.

BELL. G. L. BLOHBEBG, C. Computer simulation as a visual aid in a video Competition, coexistence and irreversibility in coarse models of early molecular evolution 482-19248 482-20951 BELOIABISBV, F. f. BLDIB, B. J. 4 comparative evaluation of the heaodynamic Staying sane in space effects of large doses cf morphine, dipidolor, 482-19743 pentazocine, and phentanyl BOCHK4BEV, V. K. A82-21795 The use of. linear models for EEC analysis BEiSOB, fl. 482-20326 Body temperature changes during the practice of g BOBV, f. H. Tnm-mo yoga Functional state of the hippocampal-reticnlar 182-21213 complex under submaximal physical load and fatigue BEIS01, B. 482-21786 Photolysis of CH4-SH3 mixtures and EH3 as models BOIADZBIEVA-aiKBULOVA, A. for the photochemical transformations on the Investigation of the otolithic membrane of the primitive earth and Jupiter utricle of the guinea pig 482-20911 482-20301 BBBDICHEVSKAIA, B. H. BOKSEB, 0. IA. The relationship between cardiac and motor 4 systems analysis of human motor reactions in components of a conditioned reflex upon the various nodes of operation of goal-directed local cooling of various zones of the cerebral behavioral acts cortex in cats 482-21729 482-21787 BOBDABEBKO, B. A. BEHDISHE?, 1. V. Change in the nature of the psychotropic effect on Lavs governing readaptation for seamen after a the emotional reactivity and behavior in stress . low-latitude cruise situations depending on the state of .the 482-20310 catecholaminergic systems of the brain BEBDTSHEVA, L. V. 482-21739 Functional condition of the rat sympato-adrenal BOHD4BEHKO, V. I. system during emotional and nociceptive stress Effects of dioxalim and oxamide on succinate and 482-20335 lactate dehydrogenase activities in rat liver, BEBGBB. B. L. kidney and brain tissues and on the chromosomal Variability of oxygen affinity of blood - Human apparatus of bone marrow cells subjects native to high altutude 482-21778 482-19493 BOSBilTZ, B. F. BEBSHJISKAIA. O. B. Mechanisms of cadmium absorption in rats Cellular mechanisms of the Frank-Starling phenomenon [PB82-108184] H82-16703 482-21456 BOBBEB. B. A. BBBSHTBIi, S. A. The radiolysis and radioracemization of amino Contractile dysfunction of vascular wall smooth acids on silica surfaces muscle under emotional ncciceptive stress 482-20019 482-20322 4 model for the enantiomeric enrichment of BEBTHOZ, 4. polypeptides on the primitive earth Difference between eye closure and visual 482-20020 stabilization in the control of posture in man Search for effect of longitudinally polarized A82-21686 protons on optically active amino acids BB1SKII, 0. 7. 482-20021 Effects on biological systems of electromagnetic BOOIB, F. B. oscillations in millimeter range of wavelengths Enzymatic capacities of skeletal muscle - Effects H82-17849 of different types of training BEZUHOVi, I.. I. 482-22248 lexicological and hygienic aspects of improving BOOZE, C. F., JB. additional purification of water reclaimed from The prevalence of visual deficiencies among 1979 urine general aviation accident airmen 1182-16718 482-21688 BIESIBG, c. BOBODOLIBA, I. I. First aid for thorax traumas: Thorax drainage Ainino acid metabolism during prolonged intake of through suction - Beport on 25 cases dehydrated foods and simulation of some space 482-19016 flight factors BIKHHUK, I. I. N82-17816 Changes in the structure and cellular composition BOSSABD, A. of the inguinal lymph nodes of white rats Organic chemical evolution of reducing model of subjected to static and dynamic stresses the atmosphere of the primitive earth - Bole of 482-21761 DV light and electric discharges BILLflAB. G. B. 482-20912 The effects of horizontal body casting on blood Far UV photolysis of methane-water gaseous volume, drug responsiveness, and +Gz tolerance mixtures and the prebiotic synthesis of aldehydes in the rhesus monkey 482-20913 482-21682 BOOGHNEB. B. E. BIXBI, S. A. Comets and the photochemistry of the paleoatmosphere Physical performance tasks reguired of 0. S. 482-20866 Hatines operating in a desert environment BOVE, J. B. [40-4107866] N82-17863 Effect of blood volume on sweating rate and body BL4IB, B. E. fluids in exercising humans 4 model for the enanticmeric enrichment of 482-19495 polypeptides on the primitive earth BOBLES, B. L. 482-20020 4 pr.ogram for assessing pilot mental state in BLIHOV, a. B. flight simulators Blood serum nuclease activity in healthy persons [4144 PAPEB 82-0257] A82-22078 and patients with various hematological diseases BH4CK, A. 482-21813 Search for primitive replicative properties on BLOCB, a. B. early polypeptides 4biotic organic synthesis in space 482-20963 482-20910 BBAHDT, 1. BLOCfl, S. Postnrography of ataxia induced by Coriolis- and Photoassisted carbon dioxide reduction and Purkin je-effects formation cf tvoand three-carbon compounds 482-21684 482-20920

1-53 BBA«TO»». S. S. PBBSOBA1 AOIHOB IBDEI

BBA9TOVA, S. S. BOfET, B. Effect of space flights of different duration on The role of analytical procedures in the formation energy metabolism of huaan erythrocytes of biochemicals froo experiments simulating the B82-17817 chemical evolution of prioeval earth BBBIDEBBICH, S. 1. A82-20927 Development of the Autoaated Performance Chemical evolution of model systems of primeval Assessment and Bemedial Training System earth periphery and thermal polymerisation of (&PABTS) : 4 landing signal officer training aid aqueous solutions of cyanides £40-4106224] H82-17873 482-20933 BBICB, 0. Selective acylability of amino acids by Selective acylability of aiino acids by non-enzymic oodel reactions of biochemical non-enzynic model reacticns of biochemical transacylations transacylations 482-20965 A82-20965 Could the biochemical metabolism be different BBICTSO1. C. A. 482-20976 Development of the Aatoaated performance BICHKOf, ». P. Assessment and Bemedial Training System Diet of crews of three main expeditions aboard (APAB1S) : A landing signal officer training aid Salyut-6 orbital station [AD-A106224] H82-17873 H82-17815 BBIDSOI, P. K. Amino acid metabolism during prolonged intake of Template-directed synthesis of oligogaanylic acids dehydrated foods and simulation of some space - Metal ion catalysis flight factors 482-20932 H82-17816 BBOCH. H. Human lipid metabolism during confinement in Quantum mechanical conformational analysis of pressure chamber aminoacyladenylates - Iiplication in the origin H82-17822 of life Vitamin C, B sub 1 and B sub 6 excretion in urine 482-20941 during 182-day antiorthostatic hypokinesia BBOBOVITSKAIA, Z. 6. H82-17824 Brain monoamine ozidase activity daring cold BIKOV, B. L. adaptation and under the combined effects of The temperature dependence of the kinetics of cold and hyperbaric ozygenation isometric myocardium relaxation 482-197i»6 482-19718 The effect of lov temperature on the activity and substrate specificity of lonoamine ozidases in rat brain mitochondria 482-21735 CABHOL, D. BBOOKS, J. Quantum mechanical conformational analysis of Organic matter in meteorites and Precambrian rocks aminoacyladenylates - Implication in the origin - Clues about the origin and development of of life living systems 482-20941 482-21988 CABBELL, B. A. BBOil, B. S. Studies on structure and function relationship in Genetic damage in Eschericbia coli K12 4B2480 by fibrinogen broad-spectrum near-ultraviolet radiation B82-17859 482-22200 CHABDABOVA, B. B. BBOBB, B. D. Comparative antihypoxic efficacy of pressure interstellar molecules and the origin of life chamber conditioning and fasting of man 482-20902 H82-16729 BDCKPIII, A. B. Antihypoxic efficacy of intermittent mode of Comparative biochemistry and metabolism. Part 2: pressure chamber conditioning of man Naphthalene lung toxicity H82-17827 [AD-4107673] 882-17842 CHAIALO, P. P. BOCAIUA, A. S. The effect of physical training on the lipid and Effect of calcium on the temporal characteristics lipoprotein metabolism in people of various ages of nuscle contraction 482-21757 482-21708 CHAHEIDES, i. L. BOLABv, ID. O. Bates of fixation by lightning of carbon and loe functional condition of the ampullar apparatus nitrogen in possible primitive atmospheres in Heniere's disease 482-20016 A82-20308 CHAPLII. B. P. BOUAZIAB, A. A. Effect of calcium on the temporal characteristics Computer-aided analysis of the effect of the of muscle contraction initial narcosis on the central hemodynanics 482-21708 482-21797 CHABACHE. S. BOBAVKOTA, L. B. Variability of oxygen affinity of blood - Hunan 4 combined method for the study of tissue subjects native to high altntude respiration under conditions corresponding to A82-19493 natural gas homeostasis CHBBBHKOVA, i. V. 482-20321 The structural and functional organization of the BOBS BE. r. J. ventrolateral nucleus of the thalamus Cardiovascular origins of heatstroke 482-21155 pathophysiclcgy - An anesthetized rat model CBBBETIASKO. I. ?. 482-21687 Particular features of conditioned BUBBAZIA1, A. I. electrodefensive reflex in white rats on. Status of space biomedical programs background of constant magnetic field H82-17239 1182-17851 BOBBS, J. B. CBBBBIAE07, G. H. Begional distribution of cardiac output in Effect of hypogeoaagnetic field on activity of unauesthetized baboons daring +Gz stress with some cerebral enzymes and without an anti-G suit H82-17853 482-21681 CBEBBISHBVA. O. B. BOTtEB. G. V. Features of metabolic disturbances in rat gorking in space myocardium under effect of alternating magnetic 482-20772 fields of different parameters BUSTEBBAOSH, I. H82-17846 Pilot vorkload: 4 survey of operational problems CAD-&107756] H82-16745

1-54 PBB5O8AL A01BOB IBDBI DELSBHHB, A. H.

CHBSTOKHI1. V. «. COBHIHGS, B. A. Jugular, right atrial pressure and cerebral Hicrobiologically-nediated mutagenic activity of heoodynamics of healthy nan submitted to crude oil postural tests [PB82-105131] H82-16702 M82-17825 CDB1IS. A. V., JR. CHICHKII. I. 6. Physical performance tasks required of 0. S. Deontology in the practice of otorhinolaryngology Marines operating in a desert environment A82-20312 [4D-4107866] 882-17863 CHIBVA, e. I. The influence of muscular work on the vestigial effects of cold acclination 482-19749 DAHIELS, •. I. CHISTfAKOV, ». A. The effect of two years' training of aerobic power Simulation of some of man's movements in different and muscle strength in male and female cadets gravity fields A82-21678 882-16712 DAODOVA. S. H. CHIZHOV, e. K. Temperature dependence of alanine and aspartate Inf oruativeness of ultrasonic Doppler cardiography aminotransferase activities in rat brain daring in evaluation of coronary circulation hypothermia of various durations and adrenalectomy 882-17828 A82-21812 CHIZHO*. S. V. DAYID, A. Hygienic principles of ongoing monitoring of First aid for thorax traumas: Thorax drainage quality of recycled Hater during space flights through suction - Beport on 25 cases H82-16717 A82-19016 Comparative evaluation of antimicrobial activity DAVIES, E. B. of some urine preservatives Bate of uptake of carbon monoxide at different N82-17830 inspired concentrations in humans CHBISiOPflBBSOS. S. K. A82-21930 Pulmonary gas exchange during altered density gas DAVIK, Z. F. breathing Dltrastructure of blood vessels and muscle fibers 482-21935 of rat skeletal muscles after flights aboard CHOLHAS, I. Cosmos-605 and Cosmos-782 biosatellites Sorepinephrine and enzymes of synthesis and 882-17835 degradation thereof in the rat hypothalamus DAVIS, P. 0. following flight aboard the Cosm.os-936 Physical performance tasks required of 0. S. biosatellite Marines operating in a desert environment 882-16716 [AD-A107866] 882-17863 CHUB, S. F. S. DAVIDOV. A. A. Organic and inorganic interpretations of the 4 study of tropomyosins in human muscular and Dartian UV-IB reflectance spectrum nonmuscular organs 482-21208 482-21806 CHUBCH, J. P. DAVIDOV, 6. A. A model for essential hypertension: Metabolic Comparative antihypoxic efficacy of pressure studies chamber conditioning and fasting of man H82-17867 H82-16729 CHDBIBA, S. K. Antihypoxic efficacy of intermittent mode of Effects of embient parameters on man pressure chamber conditioning of man H82-17826 882-17827 CLABK, J. C. DAVIDOVA, 8. A. Bate of uptake of carbon monoxide at different Human adrenosympathetic system during immersion in inspired concentrations in humans water 482-21930 882-17819 CLEVBISOI, S. A. DAIBOFF, H. 0. An evaluation of helicopter noise and vibration Phylogenetic sequence of metabolic pathways in ride gualities criteria Precambrian cellular life £8AS4-TH-83251] B82-17871 482-20967 CLOKE, S. L. The evolution of blue-greens and the origins of In vitro Ca-U5/»*/ uptake and exchange by chloroplasts otoconial complexes in high and low K/+/Na/+/ A82-20971 fluids Evolution of the rbodospirillaceae and 482-2221*9 mitochondria - A view based on sequence data COHE, B. V. A82-20972 Chemicals Identified in Human Biological Media DECKEB. S. [DE81-030813] 882-16735 Formation of energy rich phosphate in Fenton's COBSfABTIBESCO, A. reaction Abiotic synthesis of phosphoric esters of A82-20922 monosaccharides according to the 'cold model1 Experiments on transfer of organic molecular 482-20923 information into crystal lattice superstructures COHVBBTIHO, V. A. A82-20966 Orthostatic fluid-electrolyte and endocrine Coupling to solar energy: Sensitized responses in fainters and nonfainters photoreactions - The primary source of 482-19192 self-organization COBZET1, H. E. 482-20968 Search for effect of longitudinally polarized DEBT, L. I. protons on optically active amino acids The effect of cold stress on the level and 482-20021 activity of microsomal cytochrome P-U50 in the COBS01, C. rat liver In vitro Ca-U5/++/ uptake and exchange by A82-21732 otoconial complexes in high and Ion K/+/Ha/V DEGTTABBV. V. A. fluids Cardiac output and cardiac cycle phase structure 482-22249 of pilots during flights COT8B, L. S. 882-17821 Clays as prebiotic photocatalysts Informativeness of ultrasonic Doppler cardiography 482-20916 in evaluation of coronary circulation COLLflABB, G. 882-17828 A mathematical method for the enumeration of DELSBHHE. A. H. doublet codes Are comets connected to the origin of life 482-20953 A82-20865

1-55 DBBBO, A. G. EEBSOHAL ADTHOB IHDBI

Sature and origin of organic molecules in comets DOBOSHE7, 7. G. A82-20906 Results of study of hemodynamics and phase DEHBO, A. G. structure of the cardiac cycle during functional Investigation and evaluation of cardiac test with lover body negative pressure during arrhythmias in health; jcung persons 140-day Salyut-6 station flight A82-21710 H82-16722 DBBIABEIKO, V. S. DOiLEB, B. J. 7estibnlar responses of nenrons in the feline Chemical evolution and plate tectonics anterior suprasylvian gyros and their A82-20918 interaction with responses to acoustic and DBOZDOfA, I. I. facial stimuli Combined effect of simulated weightlessness and A82-20309 accelerations on energy metabolism enzymes DBBIDO7, A. S. H82-17820 Introduction prognosis and its methodological DOK07, 1. G. aspects Pulmonary shunting and its regulation A82-21722 A82-21728 OKIES, P. DOBAHSKII, ID. D. The cold theory of the origins of life - Metabolic change in test animals as an indicator Assumptions for the theory and experimental of the biological effect of an electromagnetic evidence field having a frequency of SO Hz A82-20935 A82-21758 The appearance of protobicpolymers and DOHIXBIO, S. protooeobranes in accordance Hith the 'cold Abiotic synthesis of phosphoric esters of theory' of the origins of life monosaccharides according to the 'cold model' A82-20936 A82-20923 DBBISO7, E. I. D70BECBBHSKAIA, G. IA. Methods for diagnosing hearing loss in workers The role of natriuresis in the prophylactic effect exposed to high noise levels in accordance with of adaptation to hypoxia in the case of state standards hereditary hypertension 482-21793 A82-21712 Hygienic standards for industrial noise DTIBIK, 7. V. A82-21794 The relationship between carbohydrate and lipid OBBISO7, V. I. metabolisms in muscle cell energetics under the Systemic and cerebral heoodynamics in flight influence of ATPase loading - Mathematical model personnel exposed to moderate hypoxia A82-21706 H82-16707 DZHALAGOHIIA. SB. L. DEHUIZIO. A. G. The effects of daily blood sampling on creatine Effects of vasopressin administration on diuresis phosphokinase, aspartate aminotransferase and of vater immersion in normal humans alanine aminotransferase activities in the blood A82-19191 serum of the monkey DE7IABIB, E. A. A82-21811 Development of an integrated walking robot OZBIKIOZE, E. K. A82-18988 Changes in morphological and cytogenetic DB7IAXKO7, B. 0. hematopoietic indicators in hamadryas baboons Effects on biological systems of electromagnetic exposed to chronic low-level radiation oscillations in lillimeter range of wavelengths A82-21726 H82-17849 DZIAE, 7. H. DIACBEHKO, A. I. flechanisms of compensation and adaptation in The effect of blood pressure in the pulmonary relation to the hyperfunction of the heart artery on gas exchange in functionally A82-21756 heterogeneous lungs A82-21738 OICKEZ, 0. X. The effects of horizontal body casting on blood EBEBT, T. J. volume, drug responsiveness, and *Gz tolerance Snmmated circulatory responses of thermal and in the rhesus monkey baroreflexes in humans A82-21682 A82-21933 DILLS, J. B. EOBLSOH, B. H. The prevalence of visual deficiencies among 1979 Clay-mediated reactions of HCN oligomers - The general aviation accident airmen effect of the oxidation state of the clay A82-21688 A82-20917 DITIAXBV. V. E. EGABI, T. Seasonal rhythm of the imnune reactivity and heart Genesis of amino acids in the primeval sea - tolerance to physical load in patients with Formation of amino acids from sugars and ammonia ischemia heart disease in a modified sea medium A82-21802 A82-20925 DBIIBIB7. I. B. Environmental conditions for the formation of The role of C02 in the mechanism of the reparative marigranules and kinetic studies on the formation regeneration of bone tissue /a radioisotopic A82-20942 study/ EIHGOBB, I. IA. A82-21800 Phasic energy analysis of rheoencephalograms in DHIXHITB7, A. 7- the detection of the decompensation of cerebral Hethod of recording rotatory eye reflexes hemodynamics 1182-16727 A82-21754 DHITBIIB7A. I. A. BIBICH, t. B. Bat amino acid composition after flight aboard On the polycondensation of amino acid adenylates Cosmos-1129 biosatellite on montmorillonites H82-17831 A82-20939 OOBB, G. L. BLLAISKII, B. fl. Increased excretion of urea and The possibility of using mathematical methods for H/tau/-methylhistidine by rats and humans after predicting the results of the surgical treatment a bout of exercise of patients with vasorenal hypertension A82-21927 A82-21709 DOBBACBE7A. H. 7. BLOiAH. B. A. Besnlts of study of hemodynamics and phase Cathepsin activity of skeletal muscle and structure of the cardiac cycle during functional myocardia myofibrils after exposure to test with lower body negative pressure during weightlessness and accelerations 140-day Salyut-6 station flight H82-16714 H82-16722

1-56 PBfiSOlAl ADTBOB JIDBX GALBVA, A.

EHIBBBKOf. E. Z. FLEBOV, B. V. Temperature dependence of alanine and aspartate Computer-aided analysis of the effect of the aminotransferase activities in rat brain daring initial narcosis on the central hemodynamics hypothermia of various durations and adrenalectomy A82-21797 A82-21812 FOaiB. A. H. EPSTRIH, H. Blood fibrinogen as related to immersion in water Effects of vasopressin adiinistration on diuresis for seven days and short-term space flight of Hater immersion in normal humans U82-17836 482-19491 FOHOCBKIB, I. P. EPSTBII, B. O. Effects of dioxalim and oxamide on succinate and Body temperature changes during the practice of g lactate dehydrogenase activities in rat liver, lum-mo yoga kidney and brain tissues and on the chromosomal A82-21213 apparatus of bone marrow cells EBICKSOB, J. C. A82-21778 Bistidyl-histidine catalysis of glycine FOBSXBB, B. B. condensation in fluctuating clay environments Bate of uptake of carbon monoxide at different A82-20952 inspired concentrations in humans BBSBIKO?A, ID. B. A82-21930 The existence of an endogenous biorhythm in FOBTHBI, S. B. chromatin-positive cells of the buccal Effect of blood volume on sweating rate and body epithelium in women fluids in exercising humans A82-21783 A82-19495 EVPAKOVA, 1. B. FOOLKES, B. C. Electroencephalographic correlates of the Mechanisms of cadmium absorption in rats hemispheric functional asymmetry in the human [PB82-108184] H82-16703 brain FOI, S. I. A82-21454 Terrestrial evolution of polymerization of amino BTSTAFBf. V. I. acids - Beat to AIP Complex physiological-hygienic characteristics of A82-20937 a new work-test regime for seamen FEEDHICK, J. F. A82-2171I8 On the origin of photosvnthetic eukaryotic cells - EZBOVA, I. S. Cyanidium caldarinm as a 'bridge* alga between Changes in microcirculatory flow with respiratory prokaryotic cyanobacteria and eukaryotic insufficiency rh.odophytes: Evidence from environmental, A82-20323 polysaccharide biochemistry and ultrastructural studies A82-20973 FBEHCB. A. B. FABBX, J. Effects of temperature on the duration of arousal Advanced aviation concepts evaluation through episodes during hibernation computer driven simulation A82-21934 A82-19258 FBIEBELE. E. FAKHBAI, B. Possible selective adsorption of enantiomers by Template-directed synthesis of oligoguanylic acids Sa-montiiorillonite .- Metal ion catalysis A82-20946 A82-20932 FBOLOV, B. A. FALLICE, A. E. The influence of adaptation on the periodic effect Comets and the origin of life - The stable isotope of hypoxia on the poststress activation of the approach primary immune response A82-20864 482-20320 FABBEB, t. ¥. FBOBB, F. S. Method of assessing individual resistance of rats Psychophysical evidence for more than two kinds of to hypoxic hypoxia cone in dichromatic color blindness H82-17837 A82-19608 FBDOBO¥ICB, I. B. FBUMKIH. H. I. Bhodopsin aggregation.under the damaging effects Diet of crews of three main expeditions aboard of light on the Ehotoreceptor membranes Salyut-6 orbital station A82-21705 882-17815 FEBBACIH, A. FUFACBEVA, A. A. A neutral theory of biogenesis The effect of motor activity on the development of A82-20024 cardiac arrhythmias in experimental emotional FEBBIS, J. P. stress Photolysis of CH4-NH3 mixtures and EB3 as models A82-21713 for the photochemical transformations on the primitive earth and Jupiter A82-20914 Clay-mediated reactions of HCN oligomers - The GABAI, S. S. effect of the oxidation state of the clay The effects of successive ionizing radiation and A82-20917 heat on antibody formation FESEIKO, E. V. A82-21751 Absence of the additive effect in the combined GADABSKII, B. irradiation of Crepis capillaris seeds and A histochemical investigation of the microvascular seedlings by gamma rays and neutrons effectors regulating the supply of blood to the A82-21723 cerebral cortex FIGOBBAO, A. A82-217U4 The origin and evolution of the genetic code GAIDOK, ID. S. A82-20956 Echoencephalographic indices in patients with FIUPPOV, B. B. hypertensive disease under the effect of Special and clinical physiology of hypoxic states functional loads A82-20317 A82-21753 FISK, A. 0. GALABIIOK, S. I. Control and automatic processing during tasks Particular features of conditioned requiring sustained attention - A new approach electrodefensive reflex in white rats on to vigilance background of constant magnetic field A82-19225 H82-17851 FIIGBB, C. GALEVA. A. Posturography of ataxia induced by Coriolis- and The mathematics of immunity Parkinje-effects 482-21821 A82-21684

1-57 GALITSKII, A. 1. PBBSOHAl IDTHOB IBDBX

GALIXSKII, A. L. GOLDBAH, B. I. Development of an automatic data bank for managing Body temperature changes during the practice of g physical education of students Tun-mo yoga A82-21816 A82-21213 GABZAEVA, I. A. 60LOD, I. S. The effects of successive ionizing radiation and Seasonal rhythm of the immune reactivity and heart heat on antibody formation tolerance to physical load in patients with A82-21751 ischemic heart disease G&BELIBA, I. I. A82-21802 Effects of enbient parameters on man GOLOBEVA, I. G. H82-17826 Possible use of house fly larvae for utilization GAXXI, E. of organic waste in biological life-support In vivo recording of blood velocit; profiles and systems studies in vitro of profile alterations induced 1182-16719 by known stenoses GOBBUHOVA, A. V. [PB81-244139J 1182-16738 Acute experimental emotional stress in rabbits in GAXDADIBOV, V. B. a modulated electromagnetic field Hygienic principles of ongoing monitoring of A82-20307 quality of recycled Hater during space flights Acute experimental emotional stress in rabbits S82-16717 /physiological and cytochemical aspects/ GiZEIKO, O. G. A82-21825 OSSB report: Space biology and aerospace GOBDOM. B. C. medicine, vol. 15, no. 5, Sep. - Oct. 1981 Hicrobiologically-mediated mutagenic activity of [JPBS-79346] B82-17812 crude oil GBLVICB, E. A. [PB82-105131] H82-16702 Influence of electromagnetic vaves in millimeter GOBOSHIHSKAIA, I. A. band on inductoprotein synthesis of Brain monoamine oxidase activity during cold penicillinase by staphylococcus aureus adaptation and under the combined effects of 1182-17847 cold and hyperbaric oxygenation Effects on biological systems of electromagnetic A82-19746 oscillations in millimeter range of wavelengths The effect of low temperature on the activity and H82-17849 substrate specificity of monoamine oxidases in GEIEBOSO, i. H. rat brain mitochondria Possible mechanism for chemical induction of A82-21735 chromosome aberrations in male meiotic and GOBSBKOV, S. I. postmeiotic germ cells cf mice EEG evaluation of mental stress [DE81-031999] 1182-16700 A82-21784 GB1II, A. B. GOBSBKOV. V. P. Horepinephrioe and enzymes cf synthesis and Prevention of staphylococcal infections during degradation thereof in the rat hypothalamus space flights following flight aboard the Cosm.os-936 H82-17818 biosatellite GBABOVSKOVA, L. L. 1182-16716 Brain monoamine oxidase activity during cold GEBHAB, G. I. adaptation and under the combined effects of Physical health of truck drivers in the open-pit cold and hyperbaric oxygenation mining industry of the far north A82-19746 A82-21805 GBAI, A. B. GI5SOI, C, 6. Flight simulation in the current Australian Variability of oxygen affinity of blood - Human airline scene subjects native to high altutude A82-20534 A82-19493 GBEEHBEBG. J. B. GIL-A?. E. Chemical evolution of interstellar dust - A source Besolntion of underivatized amino acids by high of prebiotic material pressure liquid chromatcgraphy, using chiral A82-20863 eluants GBIBABOV. G. A. 482-20941 Lipid spectrum of the myocardium of white rats Stereoselective interactions of small biological exposed to hypoxic hypoxia molecules N82-16724 A82-20945 GBIGOBOV, V. IA. GILLB, H.-G. The application of bicycle ergometry to the early Comparative study of several physiological detection of ischemic heart disease parameters in the evaluation of functional A82-21775 condition in nurses GBIGOBIBV. A. I. A82-21826 flethod of assessing individual resistance of rats GIBBB-SOBOLLA, A. to hypoxic hypoxia Hntagens and carcinogens - Occurrence and role H82-17837 during cheiical and biological evolution GBIISAK, A. V. 482-20975 The effect of motor activity on the development of GBEZOV, A. ?. cardiac arrhythmias in experimental emotional The myenteric plexus - Basic principles of stress modeling neuronal organization A82-21713 A82-20337 GBOSSBABB, K. GOGOSB, S. f. Physical and physiological features of long-range The effect of physical training on the lipid and flight and its impact on patients lipoprotein metabolism in people of various ages A82-19012 A82-21757 GUBIB. 10. A. GOLAR, a. B. Changes in microcircnlatory flow with respiratory Influence of electromagnetic vaves in millimeter insufficiency band on inductoprotein synthesis of A82-20323 penicillinase by staphylccoccus aureus GOLBVSKII. A. K. B82-17847 Effect of low-temperature on the membrane Effects on biological systems of electromagnetic permeability of erythrocytes reconstituted in oscillations in millimeter range of wavelengths media of different ionic composition B82-17849 A82-21737 GOLDIB, S. E. An analysis of cognitive mapping skill [AD-A106145] H82-16740 Ability differences and cognitive mapping skill [AD-A106389] B82-16741

1-58 PEBSOBAt AUIHOB IHDEI IAKOSHBV, V. S.

GOHJI, H. BECHT, K. K. Synthesis and degradation of aniuo acids by Heuronal-glial alterations in the cerebral cortex contact glow discharge electrolysis, a possible of animals under the influence of white noise route for prebiotic formation of bio-organic A82-21769 compounds BEBBOB, S. A82-20924 Pilot workload: A survey of operational probleas GOBEVICfl. H. I. [AD-A107758] B82-16745 Contractile dysfunction of vascular vail smooth BBSS, B. L. muscle under emotional nociceptive stress Beview of literature and regulation relating to 182-20322 thoracic impact tolerance and injury criteria GOBFIBKBL, f. S. £PB82-108697] B82-16736 Development of an integrated walking robot HILL, 0. A. 482-18988 Waveguide technique for the calibration of The economy of muscular work during nnfused tetanus miniature iaplantable electric-field probes for 482-21701 use in microwave-bioeffects studies The dynamics of muscular relaxation following 482-20893 unfused tetanuses of different durations HILLS, B. A. 482-21707 Air embolism - Possible role of surfactant on GOBI!, V. I. recompression The effect of synaptically active drugs on the 482-21931 hyperthermic effect cf prostaglandin £2 in rats HLASIALA, fl. P. 482-21741 Pulmonary gas exchange during altered density gas GUSEV, G. t. breathing Effects of dioxalim and oxamide on succiuate and 482-21935 lactate dehydrogenase activities in rat liver, HO, B.-L. kidney and brain tissues and on the chromosomal 4 study of treadmill exercise protocols for apparatus of bone marrow cells Chinese Bales 482-21778 482-21677 GDI, H. J. B. HOLLEBBADGH. D. D. Phase V of the single-breath washout test An evaluation of helicopter noise and vibration 482-21928 ride gualities criteria tHASA-TH-83251] H82-17871 HOLZEB, G. H Membrane lipids and the origin of life H4G4B, I. J., JB. 482-20943 Clay-mediated reactions of HCN oligomers - The HOPKIHS, J. effect of the oxidation state of the clay Body temperature changes during the practice of g 482-20917 Tum-mo yoga HAIIES, B. P. 482-21213 Orthostatic fluid-electrolyte and endocrine HOBSFIELD, K. responses in fainters and nonfainters An asymmetrical model of the airways of the dog lung 482-19192 482-21926 HALLDOBSSOH, 1. HOiBLL, i. C. Biophysical fundamentals and instrumentation for Choosing among alternatives with uncertain the endovesical Bd:ZAG-laser application outcomes: Effect of prior curing and estimation [BBB-04-581-81-0] N82-17843 requirements HALBABB, B. [AD-A106143] B82-16739 Photoassisted carbon dioxide reduction and HOTLE, F. formation of twoand three-carbon compounds Comets - 4 vehicle for panspermia 482-20920 A82-20868 HABBOBD. C. E. HBHCIB, H. A. 4n evaluation of helicopter noise and vibration Beduction of thionucleosides - 4 prebiotic pathway ride gualities criteria to deoxyribonacleosides [H4S4-TH-83251] N82-17871 482-20928 H4BSEI, B. 4. HUGHES, J. I. B. The semi-automatic instructional system Bate of uptake of carbon monoxide at different 482-20539 inspired concentrations in humans HABADA, K. 482-21930 Synthesis and degradation of amino acids by HUGHES, H. J. contact glow discharge electrolysis, a possible Alterations in responses to drugs of atria from route for prebiotic formation of bio-organic white rats acclimated to hypobaric hypoxia compounds 482-19497 482-20924 HOGH4H, G. B. Potentiometric titration behavior of polyamino Enzymatic capacities of skeletal muscle - Effects acids prepared by thernal pclycondensation of different types of training 482-20938 A82-22248 BABE, P. E. HOGDEBIB, B. L. Organic analysis of the Antarctic carbonaceous Hicrobial life in cold saline environments chondrites A82-20974 482-20908 HYATT, B. B. Besolution of underivatized amino acids by high 4 computational model for expiratory flow pressure liguid chromatcgraphy, using chiral 482-21929 eluants A82-20944 HAiKEB, J. B., JB. Cyanamide mediated syntheses of leu, ala, and phe IAGODIN, S. V. peptides under plausible primitive earth Functional characteristics of receptors connected conditions with sustaining the flight of the roach 482-20931 Periplaneta Americana L HAT, S. B. A82-21716 Detection of amblyopia utilizing generated retinal IAGOBOV, B. F. reflexes The effects of successive ionizing radiation and [HAS4-CB-161944] B82-16732 heat on antibody formation HAIASHI, fl. 482-21751 Enhanced heat production in physically restrained XAKUSHEf, Vo S. rats in hypoiia Activation of the metabolism of the A82-19496 gamma-aminobutyric acid system in the cerebral hemispheres under various types of stress 482-21746

1-59 IABTSBV, H. B. PBBSOHil AOTHOB IIDEX

IABISB*. I. fl. JOHES, H. A. Adaptation to high-altitude hypoxia at different Bate of uptake of carbon monoxide at different aobient temperatures /before and daring inspired concentrations in humans adaptation/ A82-21930 A82-21715 JOBES, P. B. IAVICH. a. F. Cardiac output increase and gas exchange at start Bucleic acid and protein metabolism in cardiac of exercise muscle A82-21936 A82-21772 IGHAIBfA, V. B. Effect of cooling of the rhythmo-inotropic ratio K in a pathological!; altered ayocardiam KAIDABOVA, E. A. A82-21740 The role of biofeedback in the adaptive regulation ILTOKHIB, A. V. of pathological bioelectric.brain activity Cytokinetic evaluation of erythrop.oiesis daring A82-20328 long-term orbital flights KAIDASH, A. H. N82-16715 Effect of cooling of the rhythmo-inotropic ratio IBGBABSOB. 0. B. in a pathologically altered myocardium Chemical evolution and plate tectonics A82-21740 A82-20918 KAKABAOZE. S. A. IBOBATA, K. Age morphofunctional characteristics of chromaffin Amino acids derivatives synthesis from nitrogen, tissue in the celiac nodes, both in the norm and carbon and water by electric discharges with hypokinesia 482-20018 A82-21766 IBVIBB, i. B. KALACHEVA, E. 1. Comets and the origin of life The significance of airflow resistance to changes A82-2090S in responses to increasing hypercapnia ISHIGAHI, B. A82-20327 Frinitive transfer BBA and origin of Darwinian KALAHDAHO?, S. system Diet of crews of three main expeditions aboard A82-20959 Salyut-6 orbital station ISLAH07, B. I. H82-17815 A comparative evaluation of the henodynamic KALBF1EISCH, J. H. effects of large doses of morphine, dipidolor, Summated circulatory responses of thermal and pentazocine, and phentanyl baroreflexes in humans A82-21795 A82-21933 ITSEKHOVSKII, O. 6. KALIBA, G. I. Besults of study of hemodynamics and phase Computer-aided analysis of the effect of the structure of the cardiac cycle during functional initial narcosis on the central hemodynamics test with lower body negative pressure daring A82-21797 140-day Salyut-6 station flight KAHEBSKIT, I. H. N82-16722 Causes of fatigue among crews of civil aviation IVABEHKO. 6. A. helicopters Features of the reaction to noise of the spinal H82-16708 capillaries of white rats Fhysiological and hygienic evaluation of vibration A82-21767 in the cockpit of a cargo helicopter IfAIITSKAIA, T. «. N82-16709 An electron microscope study of hyperplasia in KAHYSHB7A, V. A. fibers of the skeletal muscles of athletes Change in the nature of the psychotropic effect on A82-21764 the emotional reactivity and behavior in stress 17AIOV, E. T. situations depending on the state of the Badiometric determination of potassium content in catecholaminergic systems of the brain athletes A82-21739 A82-21822 Adaptogenic effect of mebicar daring emotional IVABOf, ». A. stress, exercise, and hypoxia Functional condition and work capacity under A82-21780 mountain conditions KABAGODIHA, I. L. A82-20313 Physiological-hygienic substantiation of IVABOVA, S. fl. admissible noise level in school rooms in a hot Effect of space flights of different duration on climate energy metabolism of human erythrocytes A82-21749 H82-17817 KABAZYAB, B. B. I7ABOVA, f. A. Hortality in acute myocardial infarction as The correlation between hematologic and function of geomagnetic field activity in Yerevan biochemical indicators in the turtles lestudo H82-17852 horsfieldi KAEEDIHA, ?. S. A82-21733 The circadian rhythm of activity of adrenergic IZAKOV, ?„ IA. nerve fibers in the dura mater of rats The temperature dependence of the kinetics of A82-21743 isometric myocardium relaxation KABIHO?, B. K. A82-19748 The morphology of the longs of dogs whose movement Cellular mechanisms of the Frank-Starling phenomenon is completely restricted A82-21456 A82-21765 KABBTISKAIA, E. 6. Functional model of the conversion of stationary signals in the auditory analyzer JACOBSOI, B. 0. A82-21703 A hydrodynamic model of an outer hair cell KASPEBEE. 6. J. [HASA-IB-82773] H82-16743 Increased excretion of area and JOHABSSOH, E. L. f. H/tau/-methylhistidine by rats and humans after On the origin of organic molecules in interstellar a bout of exercise space and seme of its consequences A82-21927 482-20904 KASIAB, I. I. JOHHSOB. 0. B. Besults of study of hemodynamics and phase Mechanisms of cadmium absorption in rats structure of the cardiac cycle daring functional [FB82-10818I1] H82-16703 test with lower body negative pressure during 140-day Salyut-6 station flight H82-16722

1-60 PEBSOHAL iDTBOB IBDEI KOLG4HOV1. H. S.

KATKOV. A. I. KIB, I. B. Comparative antihypoxic efficacy of pressure Stereoselective interactions of small biological chamber conditioning and fasting of man molecules N82-16729 482-20945 Antihypoxic efficacy of intermittent mode of KIHHELH4H, I. IA. pressure chamber conditioning of man The temperature dependence of the kinetics of N82-17827 isometric myocardium relaxation KATKOV. f. I. 482-19748 Jugular, right atrial pressure and cerebral KIHJO, H. hemodynafflics of healthy man submitted to Primitive .transfer BH4 and origin of Darwinian postural tests system H82-17825 482-20959 KAVLICHE?4. I. V. KIBIEHKO, I. 4. Clinical distinctions of radiation sickness with The effect of physical training on the lipid and exposure of different parts of the human body to lipoprotein metabolism in people of various ages radiation A82-21757 H82-16726 KISELBV, ¥. I. KAiAI. K. Parameters of the interaction of bradykiuin with Asymmetrical radical formation in beta-irradiated cardiovascular system receptors D- and L-alanines A82-20332 482-20949 KLEIBEBOVA, I. H. KABABOTO, K. The effect of the prolonged administration of Asymmetrical radical formation in beta-irradiated sodium hydroxybutyrate on the physical work 0- and L-alanines capacity and muscle tissue state of rats 482-20949 482-21779 KABASHIBO, K. Adaptogenic effect of oebicar .during emotional The polymerization products of stress, exercise, and hypoxia alpha-aminopropionitrile - The component A82-21780 separation using cation-exchange resin KLIBOVSKAIA, L. D. 482-20934 Stationary magnetic fields and reticular KEIL. L. C. influences on adrenergic and cholinergic systems Orthostatic fluid-electrolyte and endocrine N82-16725 responses in fainters and nonfainters KLIOBIH, A. I. 482-19492 The correlation between hematologic and KEIS, 6. 0. biochemical indicators in the turtles Testudo Decussations in the human muscular system horsfieldi 482-21762 482-21733 KELLEB, 0. B. KLISHOV, A. A. Phasic energy analysis of rheoencephalograms in The source of reparative regeneration in skeletal the detection of the decompensation of cerebral muscle tissue hemodynamics 482-21768 482-21754 KOBAIASHI, I. KELLY, D. H. Genesis of amino acids in the primeval sea - Psychophysical evidence for more than two kinds of Formation of amino acids from sugars and ammonia cone in dichromatic color blindness in a modified sea medium A82-19608 482-20925 KEHP. H. Effects of relative metabolic rate and heart rate An asymmetrical model of the airways of the dog lung variation on the performance of flight attendants A82-21926 482-21680 KEBKAB, S. B, KOBZEV, I. A. Choosing among alternatives with uncertain Besults of study of hemodynamics and phase outcomes: Effect of prior curing and estimation structure of the cardiac cycle during functional requirements test with lower body negative pressure during £40-4106113] S82-16739 140-day Salyut-6 station flight KEBB, J. H. H82-16722 Detection of amblyopia utilizing generated retinal KOGAH, B. B. reflexes Evaluation of the functional state of the [H4S4-CB-161944] S82-16732 cardiovascular system in patients with ischemic KETIIISKII. S. A. heart disease with reference to the nature of An investigation of the biological activity of their occupational activity chalones separated from normal livers and from 482-21803 livers that are being regenerated KOICHE?, K. A. 482-21742 Investigation of the otolithic membrane of the KHBIHOBEB, I. B. utricle of the guinea pig Seasonal rhythm of the immune reactivity and heart A82-20301 tolerance to physical lead in patients with KOKOFDIA, E. ischemic heart disease Potentiometric titration behavior of polyamino 482-21802 acids prepared by thermal polycondensation KHODZHAHflEBDIBV. I. B, 482-20938 Adaptation to high-altitude hypoxia at different KOLCHISA, I. V. ambient temperatures /before and during flyocardial protein fractions and enzymatic adaptation/ activity thereof in experimental rats flown 482-21715 aboard Cosmos-936 biosatellite KHOKHLOV4, O. S. H82-17832 Human lipid metabolism during confinement in Metabolic processis in rat skeletal muscles after pressure chamber flight aboard Cosmos-936 N82-17822 H82-17833 KHBISTOV, I. KOLESOTA, H. I. Investigation of the otolithic membrane of the Some indicators of protein metabolism in utricle of the guinea pig erythrocytes during radiation sickness and 482-20301 following cystaaine injection KIEBEB-EHdOHS, 1. 482-21724 Evolving nucleotide binding surfaces KOLGAH07A, H. S. 482-20954 Myocardial protein fractions and enzymatic KIELBLOCK, A. J. activity thereof in experimental rats flown Cardiovascular origins of heatstroke aboard Cosmos-936 biosatellite pathophysiology - An anesthetized rat model H82-17832 482-21687

1-61 KOLKA, H. A. PBBSOBAL AOIHOB IBDEI

KOLKA, fl. A. KOBAL, 0. H. Erythrocyte indices daring a competitive aarathon The effect of two years' training of aerobic power A82-21932 and muscle strength in male and female cadets KOLODOB, f. A. A82-21678 Features of metabolic disturbances io rat KOZLOV, A. B. myocardium under effect of alternating magnetic Cardiac output and cardiac cycle phase structure fields of different paraneters of pilots during flights H82-17846 H82-17821 KOLOSO7A, 1. G. Informativeness of ultrasonic Doppler cardiography Perozidation of lipids in the liver and longs of in evaluation of coronary circulation rats during prolonged adaptation to the cold H82-17828 A82-21736 KOZM7SKAIA. B. B. KOUAGIB, V. I. Adaptogenic effect of nebicar during emotional Cardiac output and cardiac cycle phase structure stress, exercise, and hypoxia of pilots during flights A82-21780 H82-17821 KBABEB. S. J. KOBAKBETICH, I. 6. Forward mashing of auditory nerve (H sub 1) and Evaluation of man's endurance of local pressure to brains tea responses (Have V) in humans the head and objective assessment of hygienic H82-17860 specifications for protective helaets KBASOtCBEBKO. L. B. H82-16710 Distinctions of regeneration of confined KOH0ALESKO, 7. t. atmosphere by means of photosynthesis of An electron nicroscope stud; of hyperplasia in unicellular algae fibers of the skeletal muscles of athletes H82-16720 A82-21764 KBADZ, V. A. KOBSXABTIBO7SKII, 6. A. Functional state of the hippocampal-reticular Condition of meningeal nervous system during complex under snbmaximal physical load and fatigue repeated exposure to transverse accelerations A82-21786 H82-16730 KBA7EIS. B. Z. KOPBIZKI. B. I. Trial on the use of stabilography in the medical Alterations in responses to drugs of atria from supervision of boxers white rats acclimated to hypobaric hypoxia A82-21817 A82-19497 KBICBB1SKAIA, A. A. KOETBLO7, 10. H. Brain monoanine oxidase activity during cold Frequency characteristics of visual evoked adaptation and under the combined effects of potentials in different regions of the human cold and hyper baric oxygenation cerebral cortex A82-19746 A82-20314 The effect of low temperature on the activity and KOBOBOV, B. B. substrate specificity of monoamine oxidases in Functional condition and work capacity under rat brain mitochondria mountain conditions A82-21735 A82-20313 KBOEHBB, K. H. B. KOB01KO7A, I. P. Evaluation of maximal and submaximal static muscle lexicological and hygienic aspects of improving exertions additional purification of water reclaimed froa A82-19223 urine KBOTOVSKII, G. S. H82-16718 The possibility of using oathematical methods for KOBOVIB, S. E. predicting the results of the surgical treatment Introduction prognosis and its methodological of patients with vasorenal hypertension aspects A82-21709 A82-21722 KOBAB7A, O. F. KOBSHOB, H. B. Heuronal-glial alterations in the cerebral cortex Summary of a discussion on the problem of the of animals under the influence of white noise 'biological norm' /in relation to an assessment A82-21769 of criteria of the harnfnlness of chemical KODBIASB07, 10. B. effects/ The effect of cold stress on the level and A82-21750 activity of oicrosomal cytochrome P-450 in the KOBSHOBO1A, 1. A. rat liver Vitamin C, B sub 1 and B sal 6 excretion in urine A82-21732 during 182-day antiorthostatic hypokinesia KODBIB, I. 0. H82-1782U Functional condition and work capacity under KOSICHBHKO, 1. f. mountain conditions Changes in morphological and cytogenetic A82-20313 hematopoietic indicators in hamadryas baboons KOLIKOV, 7. ID. exposed to chronic low-level radiation Peroxidation of lipids in the liver and lungs of A82-21726 rats during prolonged adaptation to the cold KOXBA, B. K. A82-21736 Organic analysis of the Antarctic carbonaceous KOLIBSKII, 7. I. cbondrites Activation of succinate dehydrogenation in rat 482-20908 liver by noradrenalin, cAMP and acute cooling KOXS. IA. fl. A82-21734 Pulse rate evaluation of the relative KOSTSBVICH, A. K. physiological intensity of aerobic muscular work Activation of succinate dehydrogenation in rat A82-20331 liver by noradrenalin, cAHP and acute cooling K07A1BIKO, B. A. A82-21734 A combined method for the study of tissue KOBBAH07A, G. 0. respiration under conditions corresponding to Functional condition of the rat syopato-adrenal natural gas bomeostasis system during emotional and nociceptive stress A82-20321 A82-20335 KO7AJ.BHKO, I. A. KOBKIBA, 1. B. Comparative antihypoxic efficacy of pressure Hyocardial protein fractions and enzymatic chamber conditioning and fasting of nan activity thereof in experimental rats flown H82-16729 aboard Cosmos-936 biosatellite Antihypoxic efficacy of intermittent node of H82-17832 pressure chamber conditioning of man Metabolic prjocessis in rat skeletal muscles after H82-17827 flight aboard Cosmos-936 H82-17833

1-62 PEBSOHA1 ACIflOB IHDBX LEHHOH, B. H.

KOSASO, I. LABIOBOV, S. H. Amino acids derivatives synthesis from nitrogen, Changes., in microcircnlatory flov Kith respiratory carbon and Hater by electric discharges insufficiency A82-20018 A82-20323 KDSBBEB, D. LASHCHOK. A. A. Extreme environments - ire there any limits to life Certain features of cerebral hemodynamics in doing A82-20869 mental vork at different air temperatures KOSKOVA, B. I. A82-21759 Changes in morphological and cytogenetic LAOGHLIH, H. H. hematopoietic indicators in hamadryas baboons Begional distribution of cardiac output in exposed to chronic low-level radiation unanesthetized baboons during +Gz stress Kith 482-21726 and without an anti-G suit KOZHICBBVA, H. A. A82-21681 Approaches to the removal of G2-chalone from the LAfBOYA, 0. I. liver of rats Evaluation of the functional state of the A82-21810 cardiovascular system in patients with ischemic KOZHISHIN, 1. E. heart disease with reference to the nature of Evaluation of the functional state of the their occupational activity cardiovascular system in patients with ischemia A82-21803 heart disease with reference to the nature of LAVBOVA, E. A. their occupational activity Investigation of the otolithic membrane of the A82-21803 utricle of the guinea pig KOZHBISOV, V. A. A82-20301 Bhodopsin aggregation under the damaging effects lAiLESS. J. of light on the photoreceptor membranes Clays as prebiotic photocatalysts A82-21705 A82-20916 KOZBEISOVA, B. A. IAZCASO-ABADJO, A. The effect of motor activity on the development of Could life have evolved in cometary nuclei cardiac arrhythmias in experimental emotional A82-20025 stress Cometary material and the origins of life on earth A82-21713 A82-20867 KOZHTK. V. I. LB POET. L. The role of urckinase in the regulation of the Selective acylability of amino acids by fibrinolytic activity of blood under normal non-enzymic model reactions of biochemical conditions transacylatious A82-21799 A82-20965 KVETBIAHSKI, B. LEAiCA. H. Horepinephrine and enzymes of synthesis and Porphyrin-like compounds genesis under simulated degradation thereof in the rat hypothalamus abiotic conditions following flight aboard the Cosmos-936 A82-20926 biosatellite LEATHBBBOOD, J. 0. H82-16716 An evaluation of helicopter noise and vibration KVIXKA, A. A. ride qualities criteria The effect of motor activity on the development of [HASA-TH-83251] N82-17871 cardiac arrhythmias in experimental emotional LEBEOBVA, H. H. stress EEC description algorithm for use in clinical A82-21713 practice and studies of work capacity A82-20304 LBBEDEVA, I. I. Comparative evaluation of antimicrobial activity LABEXSKAYA, O. I. of some urine preservatives Effect of space flights of different duration on N82-17830 energy metabolism of human erythrocytes LEBEDEVA, I. K. M82-17817 Distinctions of regeneration of confined LABOOIGOES, J.-H. atmosphere by means of photosynthesis of The origin and evolution of the genetic code unicellular algae A82-20956 H82-16720 LABBIE. A. LEBLABC, J. Glycogeo and nonspecific adaptation to cold Glycogen and nonspecific adaptation to cold A82-19494 A82-19494 LABOZA, I. P. LBDVOBA, fi. t. Storage stability and improvement of intermediate Some mechanisms of calcium transport by the moisture foods, phase 5 cardiac sarcolemma [HASA-CB-167503] 1182-16742 N82-17810 LACEY, J. C-, JB. LEHBABH, J. I. Factors influencing the rate of non-enzymatic Body temperature changes during the practice of g activation of carboxylic and amino acids by ATP Tum-mo yoga A82-20929 A82-21213 Summary of evidence for an anticodonic basis for 1EHIEIA, J. the origin of the genetic code Differences in eye movement data recorded by A82-20958 electro-oculography and corneal reflection LAHAV, I. techniques Clays as prebiotic photocatalysts A82-19224 A82-20916 1EIBAB, 0. LABABBA, I. Competition, coexistence and irreversibility in Breath-by-breath measurement of true alveolar gas models of early molecular evolution exchange A82-20951 A82-19498 IEHHOH, B. H. Cardiac output increase and gas exchange at start The radiolysis and radioracemization of amino of exercise acids on silica surfaces A82-21936 A82-20019 LAHBEBI, B. K. Search for effect of longitudinally polarized A computational model for expiratory flow protons on optically active amino acids A82-21929 A82-20021 LAPSHIHA. I. JO. The use of oxygen as the test gas in the determination of the closing volume of respiratory ducts A82-21801

1-63 LBBOIDSBA7A, I. E. PBBSOBAL AOIHOB IHDEI

IEBOBDSHAVA, B. B. LOHGO. I. The effects of daily blood sampling on creatine In vivo recording of blood velocity profiles and pbosphokinase, aspartate aminotrausferase and studies in vitro of profile alterations induced alanine auinotracsferase activities in tie blood by known stenoses serum of the monkey £PB81-2I»1139] H82-16738 A82-21811 LOSBV, T. S. LEBEOfA, B. I. Electroencephalographic correlates of the Bioenergetic characteristics of various kinds of hemispheric functional asymmetry in the human physical loads brain 482-20331 A82-21154 LESCHIBE, S. B. LOOIZEHHISBB, B. D. Comets and the origin of life Effects of vasopressin administration on diuresis A82-20905 of water immersion in normal humans flicrobial life in cold saline environments A82-19«91 A82-20971 L07EBIB6, P. LE7ABD07SKII, V. B. Pilot workload: A survey of operational problems Effects of dioxalim and oxaaide on saccinate and (AD-A107758J B82-167K5 lactate dehydrogenase activities in rat liver, LOCHBIE, 1. 7. kidney and brain tissues and on the chromosomal Absence of the additive effect in the combined apparatus of bone narrow cells irradiation of cre pis capillaris seeds and A82-21778 seedlings by gamma rays and neutrons LE7ASHOV, H. H. A82-21723 Method of recording rotatory eye reflexes 10GAH07A. I. S. B82-16727 Blood serum nuclease activity in healthy persons LE7IK, ID. S. and patients with various hematological diseases The economy of muscular work during onfased tetanus A82-21813 A82-21701 IDPAHDI8. 10; 7; The dynamics of muscular relaxation following Comparative neurophysiological characteristics of nnfused tetanuses of different durations cold and caudate tremors A82-21707 A82-21790 LE7IIB, J. S. LICHAK07, D. 7. Comets and the photochemistry of the paleoatmosphere Investigation of the otolithic membrane of the A82-20866 utricle of the guinea pig LE7SHIBA, I. E. 662-20301 Meuronal-glial alterations in the cerebral cortex of animals under the influence of white noise A82-21769 M LE7SOV, V. A. BAGAI, H. P. Changes of the aggregation and orientation Physiological-hygienic substantiation of structure of blood in pulsating flow admissible .noise level in school rooms in a hot A82-20333 climate LEiABOOHSKI. P. P. A82-21749 7TOL/STOL visual study BAIABSKAIA, B. B. [HASA-CB-166292] B82-17872 Lysosomes under conditions of stress LIFSHITS, B. I. A82-21770 The dynamics and physiological importance of the HAILIAN, E. S. activation of the gamma-amino-bntyric acid A combined method for the study of tissue system in the brain and cardiac muscle under respiration under conditions corresponding to pain and emotional stress natural gas homeostasis A82-21808 A82-20321 LIGHT, E. BAKH07, A. B. Alterations in responses to drugs of atria from Influence of electromagnetic waves in millimeter white rats acclimated to hypobaric hypoxia band on induetoprotein synthesis of A82-19497 penicillinase by staphylococcns aurens LIUBCHIBSKII, E. B. H82-178U7 Trial on the use of stabilography in the medical Effects on biological systems of electromagnetic supervision of b.oxers oscillations in millimeter range of wavelengths A82-21817 H82-17849 II7SHIIS, T. A. HAKI, B. Bhodopsin aggregation under the damaging effects Asymmetrical radical formation in beta-irradiated of light on the photoreceptor membranes D- and L-alanines A82-21705 A82-209U9 LKHAGVA, i. BALBOXBA, H. S. Phenomena of fluctuation of human reaction to Body temperature changes during the practice of g autiorthostatic position Turn-mo yoga H82-16721 A82-21213 LOBACHB7A, G. V. BALIEO7, 0. B. Toxicological and hygienic aspects of improving The dynanics of protein and nucleic acid content additional purification of water reclaimed from in rat raphe nucleus cells after total urine deprivation of sleep /in a rotating cylinder/ H82-16718 and selective deprivation of its paradoxical phase LOBAOGH, P. A. A82-21718 Human auditory brainstem electric responses to BABIE, A. P. binaural and monaural stimuli Antihypoxic efficacy of intermittent mode of H82-17861 pressure chamber conditioning of man LOEBKO, 10. H. B82-17827 The influence of some triterpenic gljcosides on HAHJOQ, B. C-14-alanine inclusion into the bone-narrow Cardiovascular origins of heatstroke cells of rats pathophysiology - An anesthetized rat model A82-20306 A82-21687 LOHBHABB, B. BABOSHKIHA, S. B. Template-directed synthesis of oligognanylic acids Bhodopsin aggregation under the damaging effects - Metal ion catalysis of light on the photoreceptor membranes A82-20932 A82-21705 LOBO7, B. F. BAHOH07. 7. I. Psychological probleas in the mutual adaptation of Effects of embient parameters on man man and machine in ccntrcl systems H82-17826 A82-19000 PBBSOBAL AOIBOB IBDEZ BIBOSBHIKOVA, I. B.

HAHUKflU, B. «. Activation of the metabolism of the Functional condition of the rat syupato-adrenal gaama-aminobntyric acid system in the cerebral system during emotional and nociceptive stress hemispheres under various types of stress A82-20335 A82-217U6 HABBA1, E. The dynamics and physiological importance of the Begulatioii of calcium current and calcium activity activation of the gamma-amino-butyric acid ill heart cells system in the brain and cardiac muscle under H82-17870 pain and emotional stress HABKABTAi. H. V. A82-21808 Diet of creus of three main expeditions aboard BBILABOV. I. S. Salyut-6 orbital station Temperature dependence of alanine and aspartate H82-17815 aminotransferase activities in rat brain during HABKHASIU. V. S. hypothermia of various durations and adrenalectomy Cellular mechanisms of the Prank-Starling phenomenon A82-21812 A82-2K156 BEIBDL. J. D. BABKHIHI8. B. K. Hicroelectronics and computers in medicine New data on abiogenic synthesis at prebiological A82-21268 compounds in volcanic processes HELBSHKO, G. I. A82-20017 Distinctions of regeneration of confined HABKIH, A. s. atmosphere by means of photosynthesis of Positions, movements and equilibrium of rats after unicellular algae flights aboard biosatellites H82-16720 1182-16713 BELKOBOVA, 6. G, BABBADBS, KB. B. A. Poststimulatory auditory adaptation in humans Dynamics of the condition of granulation tissue according to computer audiometry aftec injuries sustained at different times of A82-21791 the day HELLO, B. C. A82-21763 The effect of two years' training of aerobic power HABEAS. I, S. and muscle strength in male and female cadets Evaluation of maximal and submaximal static muscle A82-21678 exertions HELHIKOVA, L. ?. A82-19223 The application of bicycle ergometry to the early HABTIBIS, G. fl. detection of ischemic heart disease In vivo recording of blood velocity profiles and A82-21775 studies, in vitro of profile alterations induced HELTOH, C. E. by known stenoses Effects of long-term exposure to lov levels of [PB81-244139] H82-16738 ozone - A review HABTXHOf, I. A. A82-21676 The effects of narcotic analgesics on animal Fatigue in Flight Inspection Field Office (FIFO) sensitivity to hypoxia flight creus A82-20316 [AD-A106791] H82-16733 HASLO?, 0. D. BBLVIB. J. H. Differentiation of muscles on the basis of Beyiew of literature and regulation relating to trace-element composition thoracic impact tolerance and injury criteria A82-2170* [PB82-1086S7] H82-16736 HASLOVA, A. I. HEBSBOTKIB, V. Y. Stationary magnetic fields and reticular Hodels of a functional lapse in one hemisphere and influences on adrenergic and cholinergic systems of the neuropharmocological effects on the deep M82-16725 structures of the brain HATVEIET, I. G. A82-20325 Physiological and hygienic evaluation of vibration BEBIYBXSOV, B. E. in the cockpit of a cargo helicopter The multiple forms of tyrosine aminotransferase in H82-16709 rat liver cells and their role in cellular HAOBO, C. A. homeostasis Acceleration measures and motion sickness incidence A82-21807 £AD-A107996] N82-16734 HESSIHA, F. HAYBABD, B. B. Alterations in responses to drugs of atria from Facilitated diffusion of small non-electrolytes in white rats acclimated to hypobaric hypoxia the human red blood cell A82-191I97 S82-17855 HICHELS, D. B. BCKBIZIB, J. fl. Phase V of the single-breath washout test Fatigue in Flight Inspection Field Office (FIFO) A82-21928 flight creus BILLABVOIE. H. [AD-A106791] H82-16733 Difference between eye closure and visual BCBAOGBIOI, B. J. stabilization in the control of posture in man Comets and the origin of life - The stable isotope A82-21686 approach HILLEB. K. J. A82-2C86U Hicrobial life in cold saline environments BECLEB. F. J. A82-20974 Mammalian toxicological evaluation of DIHP and HILLEE, S. L. DCPD (Phase 3 - IflPA) The Strecker synthesis in the primitive ocean [AD-A107574] H82-17840 A82-20919 BEEBSOB, F. Z. BIBJI, L. The influence of adaptation on the periodic effect Organic and inorganic interpretations of the of hypoxia on the poststress activation of the flartian DV-IB reflectance spectrum primary immune response A82-21208 A82-20320 HIHOVICH, A. I. Contractile dysfunction of vascular wall smooth Changes in the main characteristics of the central muscle under emotional nociceptive stress hemodynamics of healthy individuals and A82-20322 hypertension patients during physical exercise Functional condition of the rat syapato-adrenal A82-21711 system during emotional and nociceptive stress BIBOSHBIKOVA, I. B. A82-20335 Bat amino acid composition after flight aboard The role of natriuresis in the prophylactic effect Cosmos-1129 biosatellite of adaptation to hypoxia in the case of H82-17831 hereditary hypertension A82-21712

1-65. HJICHBLl, C. 8. PBBSOHiL AOIHOB ISDEX

aiXCBBLL, C. H. HAGASAKA, S. Human-machine interface issues in the Enhanced heat production in physically restrained Bultisatellite Operations Control Center-1 rats in hypoxia (BSOCC-1) A82-19496 [HASA-TB-83826] B82-17875 BA6IVABI, J. J. BITBOKBIBA, V. V. Seduction of thionncleosides - A prebiotic pathway Rationalizing physical regimen of sedentary workers to deoxyribonucleosides 482-21818 A82-20928 HOGILEVSKII. B. B. HAKAHABA. Y. Effect of cooling of the rhythmo-inotropic ratio Effects of relative metabolic rate and heart rate in a pathologically altered myocardium variation on the performance of flight attendants A82-21740 A82-21680 BOBGB. C. C. BASABO. S. Variability of oxygen affinity of blood - Human Effects of relative metabolic rate and heart rate subjects native to high altutude variation on the performance of flight attendants A82-19493 A82-21680 BOOBB, F. O. H. HAKASHIHA. 1. Flight simulation.- The military need Terrestrial evolution of polymerization of amino A82-20529 acids - Heat to ATP BO Hi, B. A82-20937 Porphyrin-like compounds genesis under simulated BABSBBBG, Z. abiotic conditions Organic and inorganic interpretations of the 482-20926 Hartian OV-IB reflectance spectrum BOfilB, O. 482-21208 Variability of oxygen affinity of blood - Human HAPKHA810K. V. K. subjects native to high altutude characteristics of the relations of the primary A82-19U93 responses of the pentose phosphate pathway to BOBIBOTO, J. I. glycolysis in the bone narrow of irradiated rats Photolysis of CH4-HH3 mixtures and PB3 as models A82-21725 for the photochemical transformations on the BABOSABA, fl. primitive earth and Oupiter Effects of relative metabolic rate and heart rate A82-20914 variation on the performance of flight attendants BOBIBOTO, S. A82-21680 The polymerization products of BASABAJAB, B. alpha-aminopropionitrile - The component Comets and the photochemistry of the paleoatmosphere separation using cation-exchange resin 482-20866 A82-20934 BAZABOf. B. B. BOOBS, B. Comparative evaluation of antimicrobial activity Clay-mediated reactions of HCH oligomers - The of some urine preservatives effect of the oxidation state of the clay H82-17830 A82-20917 BBBIEBIDZE, B. B. BOOBBI, D. Study of the electrical activity of the Formation of prebiotic precursors from model extraocular muscles reducing atmospheres Bole of hydrogen escape A82-21731 A82-20911 BELSOB, H. Organic chemical evolution of reducing model of Psychological testing at high altitudes the atmosphere of the primitive earth - Bole of A82-21679 07 light and electric discharges BEPOflSIASHCHIKH. V. A. A82-20912 Disturbances in biological rhythms as a result of BOVCB1B, V. B. a conflict of incompatible stimuli Peculiarities of the middle ear structure in A82-21720 rodents as an index of the freguency tuning of SESTEBOV. V. P. their auditory system Activity of some enzymes of carbonhydrate A82-21714 metabolism in rat skeletal muscles after space BOZIB, f. A. flight Functional condition and work capacity under 882-17834 mountain conditions BBVSKAXA. G. 7. A82-20313 Clinical distinctions of radiation sickness with BOUE1, J. B. exposure of different parts of the human body to The structure and function of chlorophyll-proteins radiation in photosystem 1 and the light harvesting N82-16726 complex of photosystem 2 BBBTOB, P. B. H82-17811 Respiratory toxicology, 1981 HDL1IBS, 0. H., JB. IAD-A107672] H82-178U1 Factors influencing the rate of non-enzynatic BICHOI, G. B. activation of carboxylic and amino acids by ATP Phase V of the single-breath washout test A82-20929 482-21928 Summary of evidence for an anticodonic basis for BIKIFOBOV. A. I. the origin of the genetic code The use of linear models for BEG analysis A82-20958 482-20326 HOBCHAEV, Z. I. BIKIFOBOV, B. I. The functional condition of the ampullar apparatus Changes of the aggregation and orientation in Heniere's disease structure of blood in pulsating flow A82-20308 A82-20333 BIKIIIB, I. P. Predicting the potentials of young swimmers based N on clinical and physiological data IADEL, B. B. 482-21810 Effect of blood volume on sweating rate and body BIKOLABV. V. P. fluids in exercising humans Evaluation of safety of decompression from the A82-19K95 critical volume of gas bubbles formed in the •A6AI. T. organism Effects of relative metabolic rate and heart rate A82-21717 variation on the performance of flight attendants BILOVA, B. S. 482-21680 Respiration of brain synaptosomes under conditions BAGAHI, K. of depolarization in rats deprived of paradoxal Effects of relative metabolic rate and heart rate sleep variation on the performance of flight attendants 482-20336 482-21680

1-66 PBBSOSA1 AUTBOB IBDBX PABOV, A. B.

HISSBIBAOH, A. OB10?A. I. B. Melanoidin polymers as possible oxygen sinks in Peculiarities of the middle ear structure in the pre-biotic oceans rodents as an index of the frequency tuning of A82-20921 their auditory system SODA, K. A82-21714 Effects of relative metabolic rate and heart rate OBO, J. variation on the perfornance of flight attendants Could life have evolved in cometary nuclei 482-21680 482-20025 •OOA, H. Cometary material and the origins of life on earth Asymmetrical radical formation in beta-irradiated A82-20867 D- and L-alanines Cyanamide mediated syntheses of leu, ala, and phe A82-20949 peptides under plausible primitive earth BOGUCHI. I. conditions Evolutionary processes of the genetic code A82-20931 A82-20957 Membrane lipids and the origin of life •OBKIBA, I. I. A82-20913 Prevention of staphylococcal infections daring Hutagens and carcinogens - Occurrence and role space flights during chemical and biological evolution N82-17818 A82-20975 BOSOfA. B. H. OSBIHA, I. Development of an automatic data bank for managing DNA-protein complex from an extreme halophile - A physical education of students histone-like protein in archaebacteria A82-21816 A82-20970 BOSOVA, I. A. OSIAPKO?1CH, V. B. Myocardial protein fractions and enzymatic Methods for diagnosing hearing loss in workers activity thereof in experimental rats flown exposed to high noise levels in accordance with aboard Cosmos-936 biosatellite state standards H82-17832 A82-21793 Metabolic processis in rat skeletal muscles after OSTBOVSKAIA, B. 0. flight aboard Cosmos-936 The effect of piracetam on the body's resistance N82-17833 to hypoxia BOVIKO7, V. S. A82-21777 Natural resistance of the organisms of seamen The effect of the prolonged administration of during postcruise rest sodium hydroxybutyrate on the physical work A82-20311 capacity and muscle tissue state of rats BOVIKOVA, B. fl. A82-21779 Mathematical model of a human operator detecting a Adaptogenic effect of mebicar during emotional signal on a noise background stress, exercise, and hypoxia A82-21893 A82-21780 HOZDBACHEV, A. 0. OSTBOVSKII, B. A. The myenteric plexus - Basic principles of Bhodopsin aggregation under the damaging effects modeling neuronal organization of light on the photoreceptor membranes A82-20337 A82-21705 NIHOF, B. A. OTTO, E. The role of intestinal nerves in the nutrient Comparative study of several physiological induced intestinal hyperemia parameters in the evaluation of functional N82-17869 condition in nurses A82-21826 OVAKIBO?, V. G. Hygienic standards for industrial noise OGAHESYil, S. S. A82-21794 Cathepsin activity of skeletal muscle and OVOD. ?. V. myocardia myofibrils after exposure to Cellular and molecular bases of local immunity weightlessness and accelerations A82-21773 N82-16714 OGIEVETSKAIA, H. fl. Differentiation of muscles on the basis of trace-element composition PAECHT-BOBOilTZ, fl. A82-21704 Polymerization of serine guanylate in the presence OHBA, H. of montmorillonite DNA-protein complex from an extreme halophile - A A82-20940 histone-like protein in archaebacteria PAIKIB, O. Z. A82-20970 Badiometric determination of potassium content in OKH01SIBSKII, 0. E. athletes Development of an integrated walking robot A82-21822 A82-18988 PAR, Z. P. OLSOI, C. B. Toxicological and hygienic aspects of improving A theory of the origin of life additional purification of water reclaimed from A82-20023 urine OBABSKII, I. B. B82-16718 Seasonal rhythm of the immune reactivity and heart PABCBBBKO, A. L, tolerance to physical load in patients with Parameters of the interaction of bradykinin with ischemic heart disease cardiovascular system receptors A82-21802 A82-20332 OBEB. A. PABG, K. 0. Cardiac output increase and gas exchange at start Organic and inorganic interpretations of the of exercise Martian DV-1B reflectance spectrum A82-21936 A82-21208 OBGE1, 1. B. PABIB. L. B. Template-directed synthesis of oligoguanylic acids Lysosomes under conditions of stress - Metal ion catalysis A82-21770 A82-20932 PABOV, A. B. OB10V, S. I. The dynamics of protein and nucleic acid content Mechanisms for the regulation of the intracellular in rat raphe nucleus cells after total calciuo distribution deprivation of sleep /in a rotating cylinder/ A82-21774 and selective deprivation of its paradoxical phase A82-21718

1-67 PAPAGIASBIS, H. 0. PEBSOSAL AOTHQH IIDBI

PAPAGIABBIS, B. 0. PULIBGEB, C. T. Liquid Hater on a planet over cosmic periods Comets and the origin of life - The stable isotope 482-20907 approach PABFEiO?A. B. V. A82-2086t An investigation of the biological activity of EIBIE, B. I. chalones separated from normal livers and fron Possible impact of cosmochemistry on terrestrial livers that are being regenerated biology - Historical introduction A82-21742 A82-21987 PABBBLL. fl. J. PISKO. 6. T. Begional distribution of cardiac output in Effects of dioxalim and oxamide on succinate and nnanesthetized baboons during +Gz stress with 1actate dehydrogenase activities in rat liver, and without an anti-G suit kidney and brain tissues and on the chromosomal A82-21681 apparatus of bone marrow cells PASHCBEBKO, P. S. A82-21778 Change in the cytochemical indicators of PIZZOLATI, P. L. carbohydrate metabolise in the peripheral blood In vivo recording of blood velocity profiles and neutrophils of pilots studies ir vitro of profile alterations induced A82-21457 by known stenoses PAS10SBBBKOV, L. T. [PBS 1-241139] H82-16738 Elevation of hypoxia resistance with the use of PLAKHTIEBKO, V. 1. gatimine Badiometric determination of potassium content in A82-20319 athletes PATBL. A. O. A82-21822 Reduction of thionncleosides - A prebiotic pathway PLATOBOV. A. K. to deoxyribonncleosides Development of an integrated walking robot A82-20928 A82-18988 PAVL01A, V. I. PLATOBOV, V. I. • Functional condition of the rat sympato-adrenal The use of oxygen as the test gas in the system during emotional and nociceptive stress determination of the closing volume of A82-20335 respiratory ducts Activation of the metabolism of the A82-21801 gamua-aminobutyric acid system in the cerebral PLBASABI, L. G. hemispheres under various types of stress Comets and the origin of life - Bibliography A82-21746 482-20871 The dynamics and physiological importance of the PLESHCHIBSKII, I. B. activation of the gamma-amino-bntyric acid Investigation of recurrent inhibition in the human system in the brain and cardiac muscle under spinal cord during static skeletal muscle activity pain and emotional stress 482-20330 A82-21808 PLESKOV4, B. V. PBHFILOV, ». P. Approaches to the removal of G2-chalone from the The effect of physical training on the lipid and liver of rats lipoprotein metabolism in people of various ages A82-21810 A82-21757 PODKLBTHOV, H. K. PBBOV, 10. B. Hew data on abiogenic synthesis of prebiological The relationship between cardiac and motor compounds in volcanic processes components of a conditioned reflex upon the A82-20017 local cooling of various zones of the cerebral POGODIH, B. A. cortex in cats The significance of airflow resistance to changes A82-21787 in responses to increasing hypercapnia PETIHA, V. P. A82-20327 lexicological and hygienic aspects of improving POGOBBLII, ?. B. additional purification of water reclaimed from Effects of pyrroxane and methylapogalantamine on urine cerebral blood circulation and oxygen regime H82-16718 482-21776 PETBOVA, H. ?. POGOZBE?A. I. D. Acute experimental emotional stress in rabbits in Bhodopsin aggregation under the damaging effects a modulated electromagnetic field of light on the photoreceptor membranes A82-20307 A82-21705 Acute experimental emotional stress in rabbits POKBOVSKII. V. B. /physiological and cytochemical aspects/ The relationship between cardiac and motor 482-21825 components of a conditioned reflex upon the PETBOfA. P. B. local cooling of various zones of the cerebral Decussations in the human muscular system cortex in cats 482-21762 482-21787 PBTBOflCH. 10. A. POLIAKOVA, A. P. The role of CO2 in the mechanism of the reparative Besults of study of bemodynamics and phase regeneration of bone tissue /a radioisotopic structure of the cardiac cycle during functional study/ test with lower body negative pressure during A82-21800 140-day Salyut-6 station flight PHILLIPS. S. 1182-16722 An asymmetrical model of the airways of the dog lung POBHAHPEBOBA, C. 482-21926 Comets and the origin of life; Proceedings of the PIABIAJIDA, I. P. fifth College Park Colloquium on Chemical Psychophysical evidence for more than tvo kinds of Evolution, University of Haryland, College Park, cone in dichromatic color blindness HD, October 29-31, 1980 A82-19608 A82-20853 PIBTSCHBAB1, fl. Organic analysis of the Antarctic carbonaceous Comparative study of several physiological chondrites parameters in the evaluation of functional A82-20908 condition in nurses Possible role of phosphine in chemical evolution 482-21826 482-20915 PIGHOLI, P. The. roie of analytical procedures in the formation In vivo recording of blood velocity profiles and of biochemicals from experiments simulating the studies in vitro of profile alterations induced chemical evolution of primeval earth by known stenoses A82-20927 (PB81-244139] H82-16738 Possible selective adsorption of enantiomers by Na-montmorillonite A82-20946

1-68 PEBSOBAL 4UXBOB IHDEI BOOIOBOV. V. B.

Organic geochemistry of tie Isua snpracmstals PBOBIAEV, f. I. 482-20961 A three-dimensional model for the arrangement of POBOHABBVA. B. I. the vascular and tubular components of the renal Methods for diagnosing hearing loss in workers osmoregulatbry apparatus exposed to high noise levels in accordance with A82-217U5 state standards PBOTSEHKO, 10. 1. 482-21793 Cellular mechanisms of the Frank-Starling phenomenon POPE. A. 1. 482-21456 4 program for assessing pilot mental state in PUTISTSB¥A, T. 6. flight simulators Functional condition of the rat sympato-adrenal [4144 PAPEB 82-0257] 482-22078 system daring emotional and nociceptive stress POPI¥ABOVA. IS. 482-20335 Noise and vibration effects on vestihular and visual functions in teenagers 482-21747 COPKOV, V. t. BADCHEBKO, H. O. The measurement of oxygen and carbon dioxide Diet of crews of three main expeditions aboard partial pressures in tissues by the gas depot Salyut-6 orbital station method N82-17815 482-20318 BADZHABOV. A. 0. POPOV, I. G. . The functional condition of the ampullar apparatus In-flight diets and quantitative adequacy thereof in Heniere's disease to pilot expenditure 482-20308 H82-17813 BAIBHAB, f. B. POEOT, B. B. Changes in microcirculatory flow with respiratory Informativeness of ultrasonic Doppler cardiography insufficiency in evaluation of coronary circulation A82-20323 H82-17828 BAHBLEB. fl. B. POPD6AEY. 1. I. Ultraviolet selection pressure in the Prephanerozoic Effect of the functional properties of the 482-20969 vestibular analyzer on the effectiveness of BABVAOD, B. instruction in gymnastics Study of homing pigeons in Brazil: Some 482-21819 preliminary results POBTDGAtOV, V. V. (INPE-2248-PBE/032] N82-17839 Acute experimental emotional stress in rabbits in BAO. H. a modulated electromagnetic field Membrane lipids and the origin of life 482-20307 482-20943 Acute experimental emotional stress in rabbits BASMOSSEB, B. E. /physiological and cytochemical aspects/ Cytologic and biochemical genetic effects of 482-21825 chemical carcinogens POSPE1O»A, 4. V. [AD-A107615] H82-17864 Approaches to the removal of G2-chalone from the BAOLIH, F. liver of rats Formation of prebiotic precursors from model 482-21810 reducing atmospheres Bole of hydrogen escape POT4POV, B. C. 482-20911 Succinate dehydrogenase and cytochrome oxidase Organic chemical evolution of reducing model of activity in tissues of rats submitted to the atmosphere of the primitive earth - Bole of long-term hypokinesia U? light and electric discharges H82-16723 482-20912 POTE, K. G. Possible role of phosphine in chemical evolution In vitro Ca-45/++/ uptake and exchange by 482-20915 otoconial complexes in high/and low K/+/Na/+/ BAIEF, S. S. fluids Systemic and cerebral hemodynamics in flight 482-22249 personnel exposed to moderate hypoxia POTOBIBSKII, 4. 6. H82-16707 EEG description algorithm for use in clinical BBBBOVA, T. B. practice and studies of work capacity Effects on biological systems of electromagnetic A82-20304 oscillations in millimeter range of wavelengths PBAPOB. S. S. M82-17849 Development of an automatic data bank for managing BEBSE, i. S. physical education of students The semi-automatic instructional system 482-21816 482-20539 PBE10BIOS, P. J. BEILLI, J. P. Cardiovascular origins of heatstroke Human reactions to elf electric and magnetic pathophysiology - 4n anesthetized rat model fields: An annotated bibliography of current 482-21687 literature PBIBILOVA, B. B. £PB82-102567] N82-16737 Some indicators of carbohydrate metabolism in rat BBIHAB. S. ?. lung during repeated and chronic hypoxia The myenteric plexus - Basic principles of 482-2C302 modeling neuronal organization PBOKIBA, B. S. 482-20337 The role of natriuresis in the prophylactic effect BEIB, B. of adaptation to hypoxia in the case of Evolving nocleotide binding surfaces hereditary hypertension 482-20954 A82-21712 BBZBIKOV, 4. G. PBOKOFEVA, B. 6. Effect of commercial frequency electromagnetic The influence of some triterpenic glycosides on field on androgen function of rat tests C-14-alanine inclusion into the bone-marrow H82-17845 cells of rats BIABOKOH, 1. f. 482-20306 The effect of physical training on the lipid and PBOKOPEIKO. T. G. lipoprotein metabolism in people of various ages Effects of dioxalim and oxamide on succinate and 482-21757 lactate dehydrogenase activities in rat liver, BODABTB, J. B. kidney and brain tissues and on the chromosomal A computational model for expiratory flow apparatus of bone marrow cells 482-21929 482-21778 BODIOBOf, T. H. Approaches to the removal of G2-chalone from the liver of rats 482-21810

1-69 BODBIGOBZ-ABBDFAT, J. PEBSOH1L AOIBOB IBDEI

BODBI60BZ-ABBOFAT, J. S4¥ELXBV, A. P. Temporal integration of acoustic power for Effect of transmeridional flights on biorhythm of interrupted stimuli at suprathreshold levels zone fornation by Streptomyces levoris B82-17856 B82-16711 BOKHIEBKO, K. 0. SAVELIBV4, ?. 6. Dltrastructure of blood vessels and luscle fibers Besults of study of hemodynamics and phase of rat skeletal muscles after flights aboard structure of the cardiac cycle during functional Cosoos-605 and Cosmos-782 biosatellites test with lower body negative pressure during B82-17835 140-day Salyut-6 station flight BOBABE1KO, V. 4. B82-16722 Bechanisms of adaptation to ergotheriic hypoxemia SAfHSKII, I. f. in athletes specializing in different sports Characteristics of the relations of the primary 482-21820 responses of the pentose phosphate pathway to BOSHCHIB4, I. f. glycolysis in the bone marrow of irradiated rats The effect of piracetaa on the body's resistance A82-21725 to hypoxia SAVKIf, 1. 6. A82-21777 Characteristics and patterns of the individual BOSS, H. 0. development of male and female rats in the light In vitro Ca-45/++/ uptake and exchange by of the energy rule of skeletal muscles otoconial complexes in high and Ion K/+/Ba/+/ A82-21721 fluids SAIGIB, 0. 482-22249 Formation of energy rich phosphate in renten's BOTEBBEBG. ?. reaction Emotions, sleep, and health A82-20922 482-21801 SCHIEBEB, B. H. BOZABOVA, V. 0. Huscle, motor cortex, cerebellar nuclear, and Characteristics and patterns of the individual spindle afferent during slow hold-ramp-hold development of male and female rats in the light position-tracking movements of the monkey's wrist of the energy rule of skeletal muscles B82-17854 482-21721 SCHLOBBB, F. F. BOBIABTSEV. V. V. Comets and the origin of life Jugular, right atrial pressure and cerebral 482-20905 hemodynamics of healthy man submitted to SCHMIDT, 0. K. postural tests Time domain identification of an optimal control B82-17825 pilot model with emphasis on the objective BOS4LOV4, B. I. function The effects of emotional activation on the spatial [NASA-CB-168487] H82-17874 synchronization of human brain biopotentials SCHHEIDEB, 8. 482-21785 Control and automatic processing during tasks BXCHKOTA, G. B. requiring sustained attention - A new approach Ihe dynamics of forming a prediction system in to vigilance goal-directed behavior A82-19225 482-21730 SCHBIEB, 1. H. Seduction of thionucleosides - A prebiotic pathway to deoxyribonucleosides A82-20928 SACKS, L. J. SCHIABTZ, A. B. Comets and the photochemistry of the paleoatmosphere Nitrogen compounds in carbonaceous meteorites - A 482-20866 reassessment SAGAIOVICH, B. H. A82-20909 Poststimulatory auditory adaptation in humans HCH oligomerization - Isolation and preliminary according to computer audiometry characterization of a new precursor of adenine 482-21791 A82-20930 S41DIV4B, J. I. SCH1ABIZ, B. fl. Fatigue in Flight Inspection Field Office (FIFO) Phylogenetic seguence of metabolic pathways in flight crews Precambrian cellular life [AD-A106791] B82-16733 482-20967 SALI4E?, ». B. The evolution of blue-greens and the origins of The effect of cuolinomimetics on the development chloroplasts of hypothermia A82-20971 482-21781 Evolution of the rhodospirillaceae and SALTISOVA, ¥. A. mitochondria - A view based on seguence data Contractile dysfunction of vascular vail smooth 482-20972 muscle under emotional nociceptive stress SCHiEEB, B. 482-20322 Experiments .on transfer of organic molecular SAHABAS. G. B. information into crystal lattice superstructures Heasurement of radio frequency permittivity of 482-20966 biological tissues with an open-ended coaxial SECKBACH, J. line. II - Experimental results On the origin of photosynthetic eukaryotic cells - 482-20892 Cyanidium caldarium as a 'bridge* alga between SABDiEB, H. prokaryotic cyanobacteria and eukaryotic The effects of horizontal body casting on blood rhodophytes: Evidence from environmental, volume, drug responsiveness, and +Gz tolerance polysaccharide biochemistry and ultrastructnral in the rhesus monkey studies A82-21682 A82-20973 SAPOZHKOV, L. K. SEKIGOCHI, C. Effects of embient parameters on man Effects of relative metabolic rate and heart rate H82-17826 variation on the performance of flight attendants SAPOZBBIKOVA, L. P. A82-21680 Dynamics of the condition of granulation tissue SELEZBBV, B. 8. after injuries sustained at different times of Computer-aided analysis of the effect of the the day initial narcosis on the central hemodynamics A82-21763 A82-21797 SAVCBEBBOV, I. I. SELITABOTA. G. F. Changes in microcirculatory flow Kith respiratory Functional condition of the rat sympato-adrenal insufficiency system during emotional and nociceptive stress A82-20323 A82-20335

1-70 PBBSOH1L AUTHOB IBDEI SIHIOHBSCD, C. I.

SBBBAI, 4. The role of analytical procedures in the formation Helanoidin polymers as possible oxygen sinks in of biochemicals from experiments simulating the the pre-biotic oceans chemical evolution of primeval earth 482-20921 482-20927 SEBEBBBBBIKOfA. I. A. Possible selective adsorption of enantiomers by Some indicators of protein metaboliso in Ha-montmorillonite erythrocytes daring radiation sickness and 482-20946 following cystaaine injection Organic geochemistry of the Isua.supracrustals 482-21724 482-20961 SBBEDBBKO, H. H. SBIBKABBfA, fl. H. Physiology and pathology of respiration and means Prevention of staphylococcal infections during of correcting oxygen deficiencies in an organism space flights /Heeting of the Interdepartmental Commission on N82-17818 the Coordination of Studies in Hedicine of the SBIBOKOV, ID. G. Academy of Sciences of the Ukrainian SSB and the The effect of the motor activity regime on the Ministry of Health of the Ukrainian SSB/ development, conservation, and regeneration of 482-20303 defensive conditioned reflexes in rats SEBGEEV, 10. P. A82-20305 An electron microscope study of hyperplasia in SBISBHABBF, ID. B. fibers of the skeletal muscles of athletes Badiometric determination of potassium content in 482-21764 athletes SBBGEY.EV, S. A. 482-21822 Lipid spectrum of the myocardium of white rats SHKABIBOV, I. B. exposed to hypoxic hypoxia Methods for diagnosing hearing loss in workers B82-16724 exposed to high noise levels in accordance with SEVASIY.ABOV4, I. A. state standards Effects on biological systems of electromagnetic 482-21793 oscillations in nillimeter range of wavelengths Hygienic standards for industrial noise H82-17849 482-21794 SBADBIBA, I. KB. SHKOROPII, 7. A. Changes of the aggregation and orientation The ultrastructure of the liver sinusoids of mice structure of blood in pulsating flow under conditions of acute stress - Borphometric 482-20333 study SHAFBAB, i. fl. 482-21782 Complex physiological-hygienic characteristics of SHMELBVA. A. B. a new work-rest regime for seamen The significance of airflow resistance to changes 482-21748 in responses to increasing hypercapnia SH4KDL4. A. ?. 482-20327 Effect of hypogeomagnetic field on activity of SHOLPO, 1. B. some cerebral enzymes Evaluation of man's endurance of local pressure to H82-17853 the head and objective assessment of hygienic SB4BK, B. C. specifications for protective helmets Comparative biochemistry and metabolism. Fart 1: H82-16710 Carcinogenesis SHOBIH, 10. P. [AD-4107614] N82-17865 Peroxidation of lipids in the liver and lungs of SHABP, D. s. rats during prolonged adaptation to the cold The effect of two years' training of aerobic power 482-21736 and muscle strength in uale and female cadets SHOBBOCK, D. 482-21678 Visual technology and the future SHCHBKOTEV, G. A. 482-20538 Frequency characteristics of visual evoked SHXBBBBBBG, ID. H, potentials in different regions of the human Nonesterified fatty acid metabolism during cerebral cortex exercise in humans 482-20314 482-21809 SHCBBBBAK. L. I. SB01ZBBHKO, I. B. LOB isoenzyme spectrum in intact and denervated Buman adrenosympathetic system during immersion in skeletal muscles of rats of various age during water cold adaptation H82-17819 482-21798 Combined effect of simulated weightlessness and SHCBEBBIDK, A. H. accelerations on energy metabolism enzymes The possibility of using mathematical methods for H82-17820 predicting the results cf the surgical treatment SHDSI. I. V. of patients with vasorenal hypertension Particular features of conditioned 482-21709 electrodefensive reflex in white.rats on SHELBPIB, ID. E. background of constant magnetic field Filtration properties of receptive fields of N82-17851 visual-cortex neurons SHVABTZ, B. 482-21470 Orthostatic fluid-electrolyte and endocrine SBBLODKO, B. S. responses in fainters and nonfainters .Differentiation of muscles en the basis of 482-19492 trace-element composition SIfllOHBSCO. B. C. 482-21704 Porphyrin-like compounds genesis under simulated SHEBSHIBA, A. H. abiotic conditions Changes in microcirculatory flow with respiratory 482-20926 insufficiency SIBIOBBSCO, C. I. 482-20323 Abiotic synthesis of phosphoric esters of SHIBIZO, H. monosaccharides according to the 'cold model* Origin and evolution of the genetic code 482-20923 482-20955 Porphyrin-like compounds genesis under simulated Evolution of the terrestrial atmosphere and its abiotic conditions fossils in biosystems 482-20926 482-20960 The cold theory of the origins of life - SHIBOIABA. A. Assumptions for the theory and experimental Organic analysis of the Antarctic carbonaceous evidence chondrites 482-20935 482-20908 The appearance of protobiopolymers and protomembranes in accordance with the 'cold theory* of the origins of life 482-20936

1-71 SIMS EH, E. PEBSOSAL AOTHOB JiDEX

SIBGEB, B. SOLOMKA, IA. A. The effects of microphones and faceaasks on LPC Computer-aided analysis of the effect of the vocoder perfornance initial narcosis on the central hemodynamics [AD-A107908] H82-1674U A82-21797 SIBIGII, V. H. SOLOVBV, A. I. Evaluation of man's endurance of local pressure to Contractile dysfunction of vascular wall smooth the head and objective assessment of hygienic muscle under emotional nociceptive stress specifications for protective helnets A82-20322 882-16710 SOLOVBVA, E. I. SIBITSIB. S. P. Seasonal rhythm of the immune reactivity and heart Activation of the metabolism of the tolerance to physical load in patients with gamma-aminobutyric acid system in the cerebral ischemic heart disease hemispheres under various types of stress A82-21802 A82-21746 SOLUB, B. S. SKIBA. B. A. The effects of narcotic analgesics on animal Electrode unit for testing human H reflex sensitivity to hypoxia H82-16728 A82-20316 SKOBIK, A. S. SPACE, G. Clinical distinctions of radiation sickness vith Search for primitive replicative properties on exposure of .different parts of the human bod; to early polypeptides radiation A82-20963 882-16726 SPASSKII, I. A. SKOBATOl, V. M. Antihypoxic efficacy of intermittent mode of Hygienic principles of ongoing monitoring of pressure chamber conditioning of man quality of recycled vater during space flights H82-17827 H82-16717 SPIEGEL, B. J. SLOA8B, B. A. The thermal response of a human in the near-zone Quantification of psychoacoustic tuning curve of a resonant thin-wire antenna sharpness: An analysis of freguency resolution A82-22206 in children and adults SPIBV.AT.EVA, H. H. H82-17857 Toxicological and hygienic aspects of improving SLOTSKEB, D. S. additional purification of water reclaimed from Complex physiological-hygienic characteristics of urine a new work-rest regiae for seamen 882-16718 A82-21748 STABSHIBOV. I. P. SBIBHOf. S. f. Antihypoxic efficacy of intermittent mode of Characteristics of the structure and functions of pressure chamber conditioning of man the middle ear of lizards N82-17827 A82-21823 STAIBAB. B. J. saifiiov, f. v. Variability of oxygen affinity of blood - Human Succinate dehydrogenase and cytochrcae pxidase subjects native to high altntnde activity in tissues of rats submitted to A82-19493 long-term hypokinesia STAOFFBB. B. S. H82-16723 The effect of two years' training of aerobic power SB1B1OVA, I. A. and muscle strength in male and female cadets Bat amino acid composition after flight aboard A82-21678 Cosmos-1129 biosatellite STBIB, B. S. 882-17831 Advanced aviation concepts evaluation through SHITH. D. B. computer driven simulation A statistical examination of three approaches for A82-19258 predicting motion sickness incidence SCBIKO, 10. B. A82-21685 Complex physiological-hygienic characteristics of Acceleration measures and motion sickness incidence a new work-rest regime for seamen [AD-A107996] 882-16734 A82-217«8 SHITH. J. J. SIBFABIAB, B. F. Summated circulatory responses of thermal and The effect of motor activity on the development of baroreflexes in humans cardiac arrhythmias in experimental emotional A82-21933 stress SHITH, H. H. A82-21713 A study of the acoustic reflex as elicited by STBPCHKOV, S. A. selected environmental noise stimuli Diet of crews of three main expeditions aboard H82-17858 Salyut-6 orbital station SHOLIABSKAIA, A. Z. H82-17815 Influence of electromagnetic waves in aillimeter STEPHBSSOH, L. A. band on inductoprotein synthesis of Erythrocyte indices during a competitive marathon penicilliaase by staphylococcus anrens A82-21932 H82-178U7 STOEIZEL, t. Effects on biological systems of electromagnetic The role of analytical procedures in the formation oscillations in millimeter range of wavelengths of biochemicals from experiments simulating the H82-17849 chemical evolution of primeval earth SOBOUV, I. I. A82-20927 The influence of muscular work on the vestigial Chemical evolution of model systems of primeval effects of cold acclimation earth periphery and thermal polymerisation of A82-197U9 aqueous solutions of cyanides SOKOJ.OV, I. G. A82-20933 Development of an automatic data bank for managing STOKS, P. G. physical education of students 8itrogen compounds in carbonaceous meteorites - A A82-21816 reassessment SOKOLOVA, D. A. A82-20909 Evaluation of the functional state of the STOHB, B. 1. cardiovascular system in patients with ischemic The effects of horizontal body casting on blood heart disease with reference to the nature of volume, drug responsiveness, and +Gz tolerance their occupational activity in the rhesus monkey A82-21803 A82-21682 SO1DATOV. V. A. STOiB, D. f. Development of an automatic data bank for managing Summated circulatory responses of thermal and physical education of students baroreflexes in humans A82-21816 A82-21933

1-72 PEBSOIil AOTflOB IHDEX TIHOFEEV, T. P.

STBABII. V. G. SVIDEBSKII, ?. L. & comparative evaluation of the hemodynamic Functional characteristics of receptors connected effects of large doses of morphine, dipidolor, with sustaining the flight of the roach pentazocine, and phentanyl Periplaneta Americana L 482-21795 482-21716 STBOOP, c. SVISTOV, ?. V. Chemicals Identified in Human Biological Media Effects of dioxalim and oxamide on succinate and [DB81-030813] H82-16735 lactate dehydrogeuase activities in rat liver, STBIDOM, B. B. kidney and brain tissues and on the chromosomal Cardiovascular origins of heatstroke apparatus of bone marrow cells pathophysiclogy - An anesthetized rat model A82-21778 A82-21687 SBEEHEI, B. SIOCHLI, fl. A. Clays as prebiotic photocatalysts Measurement of radio frequency permittivity of 482-20916 biological tissues with an open-ended coaxial SICHEIA. G. F. line. I 4 study of tropomyosins in human muscular and 482-20891 nonmuscular organs Measurement of radio frequency permittivity of 482-21806 biological tissues with an open-ended coaxial SZDMAHSK4, G. line. II - Experimental results 4 histochemical investigation of the microvascular 482-20892 effectors regulating the supply of blood to the STOCHLY, S. S. cerebral c.ortex Measurement of radio frequency permittivity of 482-21744 biological tissues with an open-ended coaxial line. I 482-20891 SOOAKOV, K. V. TABASEHKO, L. V. 4 systems analysis of human motor reactions in Effect of commercial frequency electromagnetic various modes of operation of goal-directed field on androgen function of rat tests behavioral acts H82-17845 482-21729 TABASIK, E. G. Emotional stress as a factor in cardiovascular The application of bicycle ergometry to the early disorders detection of ischenic heart disease 482-21796 482-21775 SODAKOV, S. K. TAU.OB, G. E. Acute experimental emotional stress in rabbits in Measurement of radio frequency permittivity of a modulated electromagnetic field biological tissues with an open-ended coaxial 482-20307 line. II - Experimental results Acute experimental emotional stress in rabbits A82-20892 /physiological and cytochemical aspects/ IAILOB, G. B., Jfi. 482-21825 Variation in plant response to ozone: 4 SODABBVA. S. M. conceptual model of physiological events Adaptogenic effect of mebicar during emotional [DE81-029692] H82-16701 stress, exercise, and hypoxia TEOH, K. 482-21780 The effects of horizontal body casting on blood SOGAiABA, H. volume, drug responsiveness, and +Gz tolerance Mechanisms of cadmium absorption in rats in the rhesus monkey £PB82-108184] 882-16703 482-21682 SDGIOBA, K. TEB4SA1A, J.-I. The polymerization products of Synthesis and degradation of amino acids by alpha-aminopropionitrile - The component contact glow discharge electrolysis, a possible separation using cation-exchange resin route for prebiotic formation of bio-organic 482-20934 compounds SDKHIKH, G. 1. 482-20924 The influence of adaptation on the periodic effect THOBHDIKE, P. I. of hypoxia on the poststress activation of the An analysis of cognitive mapping skill primary immune response [AD-4106145] N82-16740 482-20320 Ability differences and cognitive mapping skill SOHI1A, E. B. [4D-A106389] H82-16741 Elevation of hypoxia resistance with the use of TIGBAHIAH, B. A. gutimine Norepinephrine and enzymes of synthesis and 482-20319 degradation thereof in the rat hypothalamus SOHIS, S. T. following flight aboard the Cosmos-936 The possibility of using mathematical methods for biosatellite predicting the results cf the surgical treatment H82-16716 of patients with vasorenal hypertension Human adrenosympathetic system during immersion in 482-21709 water SOBKIiA, I. D. H82-17819 Stress and immunity in athletes Combined effect of simulated weightlessness and 482-21821 accelerations on energy metabolism enzymes SOITOI, S. H82-17820 Clays as prebiotic photocatalysts Myocardial protein fractions and enzymatic 482-20916 activity thereof in experimental rats flown SOVOBOV, G. A. aboard Cosmos-936 biosatellite Methods for diagnosing hearing loss in workers H82-17832 exposed to high noise levels in accordance with Metabolic pcocessis in rat skeletal muscles after state standards flight aboard Cosmos-936 482-21793 H82-17833 Hygienic standards for industrial noise Activity of some enzymes of carbonhydrate 482-21794 metabolism in rat skeletal muscles after space SOVOBOTA, I. P. flight Models of a functional lapse in one hemisphere and H82-17834 of the neuropharmocolcgical effects on the deep TIHOFBEV. V. P. structures of the brain The correlation between hematologic and A82-20325 biochemical indicators in the turtles Testudo horsfieldi 482-21733

1-73 TIBGBI, D. I. PEBSOBAL AOTHOB 11 DEI

TII6EY, D. I. 10BDIBV, A. A. Variation in plant response to ozone: A The correlation between hematologic and conceptual model of physiological events biochemical indicators in the turtles Testudo [DE81-029692] H82-16701 horsfieldi TISHBEE. A. 482-21733 Resolution of underivatized amino acids by high XOBFIXKO. S. A. pressure liquid chromatography, using chiral The possibility of using mathematical methods for eluants predicting the results of the surgical treatment 482-20944 of patients with vasorenal hypertension Stereoselective interactions of snail biological A82-21709 molecules IIAGI, S. A82-20945 Origin of translation - The hypothesis of XIDBOT, 1. 1. permanently attached adaptors The correlation between heaatologic and 482-20022 biochemical indicators in the turtles lestudo horsfieldi 482-21733 u fOBASBBTSKAIA, 1. A. OGLAIOT. A. I. fletabolic change in test animals as an indicator Evaluation of man's endurance of local pressure to of the biological effect of an electromagnetic the head and objective assessment of hygienic field having a freguency cf 50 Hz specifications for protective helmets A82-21758 H82-16710 TOEDA, 1. OLIABIHSKII, L. S. Norepinephrine and enzyoes of synthesis and The effect of motor activity on the development of degradation thereof in the rat hypothalamus cardiac arrhythmias in experimental emotional following flight atoard the Cosm.os-936 stress biosatellite A82-21713 N82-16716 OLLSPEBSEB, P. IOBBABBBB, T. G. Comparative study of several physiological Membrane lipids and the origin of life parameters in the evaluation of functional 482-20943 condition in nurses TOIOLIS, H. 482-21826 The appearance of protobiopolyoers and OPIOS, A. C. protomembranes in accordance vith the 'cold The biological effects of low-level ionizing theory* of the origins of life radiation A82-20936 482-20146 TOOPABCB, G. OBHAHCHBBV4. 1. G. Formation of prebiotic precursors from model The effect of motor activity on the development of reducing atmospheres Bole of hydrogen escape cardiac arrhythmias in experimental emotional A82-20911 stress Organic chemical evolution of reducing model of 482-21713 the atmosphere of the primitive earth - Bole of OSBAKOf, A. S. UV light and electric discharges Effect of space flights of different duration on A82-20912 energy metabolism of human erythrocytes Far 0V photolysis of methane-water gaseous H82-17817 mixtures and the prebiotic synthesis of aldehydes DSIK, S. V. A82-20913 Bioenergetic characteristics of various kinds of TRAKHIEBBBBG. I. B- physical loads Summary of a discussion on the problen of the 482-20334 'biological nora* /in relation to an assessment OTKIBA, H. B. of criteria of the harmfulness of chemical Comparative antihypoxic efficacy of pressure effects/ chamber conditioning and fasting of man 482-21750 H82-16729 TBOFIBOVA, I. A. Antihypoxic efficacy of intermittent mode of simulation of some of man's movements in different pressure chamber conditioning of man gravity fields H82-17827 H82-16712 IBOSHI1. A. Z. Jugular, right atrial pressure and cerebral henodynamics of healthy man submitted to TALBTSKII, S. F. postural tests flechanisms of compensation and adaptation in H82-17825 relation to the hyperfunction of the heart THOTSIOK. V. T. 482-21756 Hicrocirculation, tolerance to physical strain, VALIDBAB, A. T. and certain homeostasis parameters in patients Change in the nature of the psychotropic effect on with angina pectoris the emotional reactivity and behavior in stress 482-20324 situations depending on the state of the TBOFASOVA, L. 7. catecholaminergic systems of the brain Activation of succinate dehydrogenation in rat 482-21739 liver by noradrenalin, cABP and acute cooling 7ALIKOTA, T. A. 482-21734 Clinical results on thymectomy in patients with TSACKOT, H. B. myopathy in relation to the degree of muscular The effects of elevated environmental temperature weakness combined with radiation on the organism 482-21755 482-21752 VALISE?, I. B. ISABIOK, V. V. Coordination of processes in the hierarchic The effect of synaptically active drugs on the structure of the visual analyzer hypertbermic effect of pxostaglandio E2 in rats 482-21788 A82-21741 TAB BIJ, A. H, TOBCBABIBOTA, V. C. Increased excretion of urea and Results of study of hemodynamics and phase H/tan/-methylhistidine by rats and humans after structure of the cardiac cycle during functional a bout of exercise test with lower body negative pressure during A82-21927 140-day Salyut-6 station flight TAB BOODE, fl. H82-16722 Template-directed synthesis of oligoguanylic acids - Betal ion catalysis A82-20932

1-74 PBBSOHAL AQIBOB IHDBI 1EBEB, K.

?AB TBOBP, J. E. VLADIlUfiOVA, A. D. The Strecker synthesis in the primitive ocean Blood serum nuclease activity in healthy persons A82-20919 and patients with various hematological diseases TASIIBSCO. D. 482-21813 Quantun mechanical COD£ormational analysis of VLASOV, B. A. aminoacyladenylates - Implication in the origin The state of the vegetative functions during sleep of life 482-21771 A82-209U1 VLASOVA, X. F. VASILBV. D. f. Anino acid metabolisa during prolonged intake of The role of urokinase in the regulation of the dehydrated foods and simulation of some space fibrinolytic activity of blood under normal flight factors conditions 882-17816 482-21799 Bat amino acid composition after flight aboard VASILE?A, V. H. Cosmos-1129 biosatellite Electroencephalographic correlates of the N82-17831 differentiation between verbal stimuli during VOET. A. B. natural night sleep in humans HCN oligomerization - Isolation and preliminary 482-20315 characterization of a new precursor of adenine VASILTEf. A. B. 482-20930 Cardiac output and cardiac cycle phase structure VOLIiA. E. V. of pilots during flights Functional condition of the rat sympato-adrenal H82-17821 system during emotional and nociceptive stress VASILIBVA, I. D. A82-20335 Age related distinctions of cosmonauts regional V01KOVA, I. H. hemodynamics EEG evaluation of mental stress B82-17829 482-21784 7ATSADZE, I. G. VOLKOVA. H. A. Changes in the main characteristics of the central Clinical distinctions of radiation sickness with hemodynamics of healthy individuals and exposure of different parts of the human body to hypertension patients during physical exercise radiation A82-21711 N82-16726 VBBDA. Y. P. YOLIBSKII, B. G. Psychological problems in the mutual adaptation of The effects of narcotic analgesics on animal man and machine in control systems sensitivity to hypoxia A82-19000 482-20316 7EBBSBCHAGIHA. A. A. YOH HEIJHB. G. The role of biofeedback in the adaptive regulation Competition, coexistence and irreversibility in of pathological bioelectric brain activity models of early molecular evolution 482-20328 482-20951 TEBBSOTSKAXA. B. A. VOHBB, C. Hyocardial protein fractions and enzymatic Mechanisms of cadmium absorption in rats activity thereof in experimental rats flown [PB82-108184] H82-16703 aboard Cosmos-936 biosatellite VOBBOVI1SKII, E. G. U82-17832 Effect of cooling of the rhythmo-inotropic ratio Metabolic processis in rat skeletal muscles after in a pathologically altered myocardium flight aboard Cosmos-936 482-21740 H82-17833 VIOBII. S. A. Activity of seme enzymes of carbonhydrate Comparative antihypoxic efficacy of pressure metabolism in rat skeletal muscles after space chamber conditioning and fasting of man flight N82-16729 H82-1783U Antihypoxic efficacy of intermittent mode of VEBSHIGOBA, A. B. pressure chamber conditioning of man Cellular and molecular bases of local immunity H82-17827 482-21773 VOBKO1SKAIA. T. I. VBZBOfA, I, G. Cytokinetic evaluation of erythropoiesis during Combined effect of simulated weightlessness and long-term orbital flights accelerations on energy netabclism enzymes H82-16715 H82-17820 fIDAL, P. P. Difference between eye closure and visual w stabilization in the control of posture in man SALKEB, J. C. G. A82-21686 Bates of fixation by lightning of carbon and flKTOBOV, A. B. nitrogen in possible primitive atmospheres Prevention of staphylococcal infections during 482-20016 space flights iALTEBS, C. 1182-17818 Organic geochemistry of the Isua supracrustals VIBIIKOY, IA. . A. A82-20961 Investigation of the otolithic membrane of the IABBBB, D. utricle of the guinea pig Pilot workload: 4 survey of operational problems A82-20301 (AD-A107758J S82-16745 VIHOGBADO?, V. H. HASSEHHAH, K. Elevation of hypoxia resistance with the use of Breath-by-breath measurement of true alveolar gas gutioine exchange 482-20319 482-19498 VIHOGBADOVA, V. B. Cardiac output increase and gas exchange at start The source of reparative regeneration in skeletal of exercise muscle tissue 482-21936 482-21768 IEBB. B. B. VISHOHT, t. B. Genetic damage in Escherichia coli K12 AB2480 by The effect of synaptically active drugs on the broad-spectrum near-ultraviolet radiation hyperthermic effect of prcstaglandin E2 in rats 482-22200 A82-217U1 iBBBOB, B. VISSBB, C. B. Survival in space Emergence of flavin catalysis - An approach based 482-20257 on the concept of bioorganic evolution 1EBBB, K. 482-20964 Beview of literature and regulation relating to thoracic impact tolerance and injury criteria [PB82-1086S7] H82-16736

1-75 BBICKJUBB. B. PBBSOBAL AOTBOB IBDBI

iEICKBAII. B. YAHAGA1A, I. Comparative study of several physiological Amino acids derivatives synthesis from nitrogen, parameters in the evaluation of functional carbon and vater by electric discharges condition in nurses A82-20018 A82-21826 YABA6ABA, B. BEIBSXEII, S. Genesis of amino acids in the primeval sea - Besolution of underivatized amino acids by high Formation of amino acids from sugars and ammonia pressure liquid chromatcgraphy, using chiral in a modified sea medium eluants A82-20925 A82-20944 Environmental conditions for the formation of iEISSHAB. H. L. marigranules and kinetic studies on the formation Cardiac output increase and gas exchange at start A82-209U2 of exercise YABAI, K. A82-21936 Organic analysis of the Antarctic carbonaceous IBBGEfi, C. B. chondrites Effect of blood volume on sueating rate and body A82-20908 fluids in exercising humans YAHG. B.-J. 482-19495 Flow visualization technigues in medical and BEBBTZ, 0. A. biological applications Cerebral hemispheric activity and aotomonic A82-20778 nervous function YAEOLLIB, K. K. H82-17868 Age related distinctions of cosmonauts regional IHAT1EI, I. B. hemodynamics Problems in the rate of evolution in biological B82-17829 systems YABOBIB, A. C. A82-21989 Cardiac output and cardiac cycle phase structure BHIBBBBT, J. B. of pilots during flights Acceleration induced voltage variations in the H82-17821 electrocardiogram during exhaustive simulated YBGOBOV, A. 0. aerial combat maneuvering Results of study of hemodynamics and phase A82-21683 structure of the cardiac cycle during functional iHIPP, B. J. test with lover body negative pressure during Cardiac output increase and gas exchange at start 140-day Salyut-6 station flight of exercise N82-16722 A82-21936 IBLFIBOV, A. I. BHITB. D. H. Method of assessing individual resistance of rats Histidyl-histidine catalysis of glycine to hypoxic hypoxia condensation in fluctuating clay environments H82-17837 A82-20952 YEBOFEYE»A, I. V. BHITTBHBOBI. J. Possible use of house fly larvae for utilization Variability of oxygen affinity of blood - Human of organic wa^te in biological life-support subjects native to high altutude systems A82-19493 B82-16719 BICKBABASIiGHE, C. IBVDOKIflOVA, I. S. Comets - A vehicle for panspermia loxicological and hygienic aspects of improving A82-20868 additional purification of water reclaimed from SICKS, S. B. urine Fatigue in Flight Inspection Field Office (FIFO) H82-16718 flight crews YEflOSHEBKO, G. I. [AD-A106791] H82-16733 Features of metabolic disturbances in rat BIUEBSOB, J. B. myocardium under effect of alternating magnetic Erythrocyte indices during a competitive marathon fields of different parameters A82-21932 H82-17846 SILLIAHS, B. 1. IOSBIOA, B. Increased excretion of urea and The polymerization products of B/tau/-methylhistidine by rats and humans after alpha-aminopropionitrile - The component a bout of exercise separation using cation-exchange resin A82-21927 A82-20934 BIIS01, 1. A. YOSHIOKA, I. A computational model for expiratory flow Effects of relative metabolic rate and heart rate A82-21929 variation on the performance of flight attendants BIBSLOB. B. H. A82-21680 Variability of oxygen affinity of blood - Human IDBOGOV. ?. V. subjects native to high altutude Clinical distinctions of radiation sickness with A82-19493 exposure of different parts of the human body to BIBIH, B. L. radiation Abiotic organic synthesis in space H82-16726 A82-20910 BOLHAB, I. Origin of life; Proceedings of the Third ISSOI Seeting and Sixth ICOL Heeting, Jerusalem, ZABOLOTBYKH, V. A. Israel, June 22-27, 1980 EEG description algorithm for use in clinical A82-20901 practice and studies of work capacity BBIGHI, J. B. A82-20304 The effect of two years' training of aerobic power ZABBODIB, 10. H. and muscle strength in male and feaale cadets Psychological problems in the mutual adaptation of A82-21678 man and machine in control systems A82-19000 ZiGOBSKAYA, I. A. Effect of stationary magnetic field on the YABOKI, C. endocrine system Effects of relative metabolic rate and heart rate 882-17814 variation on the performance of flight attendants ZALBTABVA, T. A. A82-21680 The existence.of an endogenous biorhythm in YAKIBOVA, I. ?. chronatin-positive cells of the buccal Comparative evaluation of antimicrobial activity epithelium in women of some urine preservatives A82-21783 H82-17830

1-76 PEBS08AL ADTHOB IBDEX ZIBKOVBTS. 1. li.

ZALKIID, 7. I. . Types of spontaneous discharges in muscle receptors A82-21789 ZALOGOIBV, S. M. Prevention of. staphylococcal infections daring space fligbts H82-17818 ZBOBOVSK1IA, f. I. Electrode unit for testing human a reflex H82-16728 ZBOBOVSKII. A. B. A study of tropomyosins in human muscular and nonmuscular organs A82-21806 ZBHTSOVSKII, B. f. Investigation and evaluation of cardiac arrhythmias in health; joung persons A82-21710 ZHABOTIMSKII, A. H. A mathematical model of cell populations with stem cells 482-21702 ZHIBHDHSKAIA. E. A. Electroencephalographic correlates of the hemispheric functional asymmetry in the human ' brain A82-2145U ZHOBAVLBVA, H. 6. The effect of the motor activity regime on the development, conservation, and regeneration of defensive conditioned reflexes in rats A82-20305 ZHUT.KO, V. I. Age related distinctions of cosmonauts regional hemodynamics H82-17829 ZIHKOVSKIX. 1. V. Simulation of some of man's movements in different gravity fields N82-16712 ZOBBAS, I. 6. The reliability of flight personnel during the operation of the Mi-4 helicopter A82-1901U 2OTOV, f. A. Disturbances in biological rhythms as a result of a conflict of incompatible stimuli A82-21720 ZtBIl, O. E. Jugular, right atrial pressure and cerebral hemodynamics of healthy man submitted to postural tests H82-17825 ZIBKOfETS, L. IA. Comparative study of several physiological parameters in the evaluation of functional condition in nurses A82-21826

1-77 1. Report No. 2. Government Accession No. 3. Recipient's Catalog No. NASA SP-7011(232) 4. Title and Subtitle 5. Report Date AEROSPACE MEDICINE AND BIOLOGY May 1982

A Continuing Bibliography (Supplement 232) 6. Performing Organization Code

7. Author(s) 8. Performing Organization Report No.

10. Work Unit No. 9. Performing Organization Name and Address

National Aeronautics and Space Administration 11. Contract or Grant No. Washington, D.C. 205^6

13. Type of Report and Period Covered 12. Sponsoring Agency Name and Address

14. Sponsoring Agency Code

15. Supplementary Notes

16. Abstract

This bibliography lists 437 reports, articles, and other documents introduced into the NASA scientific and technical information system in April 1982.

17. Key Words (Suggested by Author(s)) 18. Distribution Statement Aerospace Medicine B ibliographies Unclassified - Unlimited Biological Effects

19. Security Qassif. (of this report) 20. Security Classif. (of this page) 21. Pages Unclass i fied Unclassified HC

For sale by the National Technical Information Service, Springfield, Virginia 22161

NASA-Langley, 1982 PUBLIC COLLECTIONS OF NASA DOCUMENTS

DOMESTIC NASA distributes its technical documents and bibliographic tools to eleven special libraries located in the organizations listed below. Each library is prepared to furnish the public such services as reference assistance, interlibrary loans, photocopy service, and assistance in obtaining copies of NASA documents for retention

CALIFORNIA MASSACHUSETTS University of California. Berkeley Massachusetts Institute of Technology. Cambridge COLORADO MISSOURI University of Colorado. Boulder Linda Hall Library. Kansas City DISTRICT OF COLUMBIA NEW YORK Library of Congress Columbia University. New York GEORGIA OKLAHOMA Georgia Institute of Technology. Atlanta University of Oklahoma. Bizzell Library ILLINOIS PENNSYLVANIA The John Crerar Library. Chicago Carnegie Library of Pittsburgh WASHINGTON University of Washington. Seattle

NASA publications (those indicated by an following the accession number) are also received by the following public and free libraries:

CALIFORNIA NEW YORK Los Angeles Public Library Brooklyn Public Library San Diego Public Library Buffalo and Erie County Public Library COLORADO Rochester Public Library Denver Public Library New York Public Library CONNECTICUT OHIO Hartford Public Library Akron Public Library MARYLAND Cincinnati and Hamilton County Public Library Enoch Pratt Free Library. Baltimore Cleveland Public Library MASSACHUSETTS Dayton Public Library Boston Public Library Toledo and Lucas County Public Library MICHIGAN TEXAS Detroit Public Library Dallas Public Library MINNESOTA Fort Worth Public Library Minneapolis Public Library and Information WASHINGTON Center Seattle Public Library NEW JERSEY WISCONSIN Trenton Public Library Milwaukee Public Library

An extensive collection of NASA and NASA-sponsored documents and aerospace publications available to the public for reference purposes is maintained by the American Institute of Aeronautics and Astronautics. Technical Information Service, 555 West 57th Street, 12th Floor. New York, New York 10019

EUROPEAN

An extensive collection of NASA and NASA-sponsored publications is maintained by the British Library Lending Division. Boston Spa. Wetherby. Yorkshire. England. By virtue of arrangements other than with NASA, the British Library Lending Division also has available many of the non-NASA publications cited in STAR European requesters may purchase facsimile copy of microfiche of NASA and NASA-sponsored documents, those identified by both the symbols "ft" and "*", from: ESA - Information Retrieval Service. European Space Agency. 8-10 rue Mario-Nikis. 75738 Paris CEDEX 15. France. National Aeronautics and THIRD-CLASS BULK RATE Postage and Fees Paid Space Administration National Aeronautics and Space Administration Washington, D.C. NASA-451 20546 Official Business Penalty for Private Use, $300

POSTMASTER: If Undeliverable (Section 158 NASA Postal Manual) Do Not Return