Preliminary Analysis of the U
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Equine Biosecurity and Biocontainment Practices on U.S
Veterinary Services Centers for Epidemiology and Animal Health November 2006 _________________________________________________________________________________________________________________________ Equine Biosecurity and Biocontainment Practices on U.S. Equine Operations With the globalization of animal industries, biosecurity General Practices and biocontainment practices play a vital role in the health of domestic animals. Biosecurity practices include General biosecurity measures taken on equine measures that reduce the risk of disease introduction on operations include isolation protocols, infection-control an operation. Biocontainment practices include precautions for visitors, and use of separate or measures that reduce the spread of disease on an disinfected equipment. Other general management operation and from one operation to another. practices address contact with other animals, potential Vaccination, another important aid in infection control, contamination of feed and water, insect control, and will be addressed in a separate information sheet. manure management. Equine diseases are spread in a variety of ways, including direct contact between equids and contact with Separation for isolation or infection control feces, insect or animal vectors, aerosol particles, and contaminated needles. Often overlooked but equally Overall, 65.1 percent of operations separated important modes of disease transmission include contact animals for isolation or infection control. For this study, with contaminated equipment, tack, transport -
Medical Management of Biological Casualties Handbook
USAMRIID’s MEDICAL MANAGEMENT OF BIOLOGICAL CASUALTIES HANDBOOK Sixth Edition April 2005 U.S. ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES FORT DETRICK FREDERICK, MARYLAND Emergency Response Numbers National Response Center: 1-800-424-8802 or (for chem/bio hazards & terrorist events) 1-202-267-2675 National Domestic Preparedness Office: 1-202-324-9025 (for civilian use) Domestic Preparedness Chem/Bio Helpline: 1-410-436-4484 or (Edgewood Ops Center – for military use) DSN 584-4484 USAMRIID’s Emergency Response Line: 1-888-872-7443 CDC'S Emergency Response Line: 1-770-488-7100 Handbook Download Site An Adobe Acrobat Reader (pdf file) version of this handbook can be downloaded from the internet at the following url: http://www.usamriid.army.mil USAMRIID’s MEDICAL MANAGEMENT OF BIOLOGICAL CASUALTIES HANDBOOK Sixth Edition April 2005 Lead Editor Lt Col Jon B. Woods, MC, USAF Contributing Editors CAPT Robert G. Darling, MC, USN LTC Zygmunt F. Dembek, MS, USAR Lt Col Bridget K. Carr, MSC, USAF COL Ted J. Cieslak, MC, USA LCDR James V. Lawler, MC, USN MAJ Anthony C. Littrell, MC, USA LTC Mark G. Kortepeter, MC, USA LTC Nelson W. Rebert, MS, USA LTC Scott A. Stanek, MC, USA COL James W. Martin, MC, USA Comments and suggestions are appreciated and should be addressed to: Operational Medicine Department Attn: MCMR-UIM-O U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) Fort Detrick, Maryland 21702-5011 PREFACE TO THE SIXTH EDITION The Medical Management of Biological Casualties Handbook, which has become affectionately known as the "Blue Book," has been enormously successful - far beyond our expectations. -
Concepts of Biocontainment & Biosafety Training
Concepts of Biocontainment & Biosafety Training UNIVERSITY OF NORTH CAROLINA - CHARLOTTE/ APRIL 30, 2014 CLIENT NAME / DATE Regulatory Guidance . OSHA Bloodborne Pathogen Standard . NIH Recombinant Guidelines – Apply to all institutions receiving NIH funding – Covers rDNA work, but also includes risk group listing . Biosafety in Microbiological and Biomedical Laboratories (BMBL) . Select Agent and Toxin regulations . Dangerous goods shipping regulations . North Carolina Dept. of Environment and Natural Resources CLIENT NAME / DATE US Guidance for Laboratories . BMBL Outlines: – Standard Microbiological Practices – Special Microbiological Practices – Safety Equipment – Facilities . Includes – Agent summary statements – BSC design and use – Toxin handling http://www.cdc.gov/biosafety/publications/bmbl5/index.htm CLIENT NAME / DATE Layers of Protection CLIENT NAME / DATE Definitions . Biohazard – A biological agent capable of self- replication that can cause disease in humans, animals, or plants – Generally, a microorganism, or toxins and allergens derived from those organisms . Biocontainment Class III cabinets at the U.S. Biological Warfare Laboratories, Camp Detrick, Maryland (Photo, 1940s) – the physical containment of pathogenic organisms or agents to prevent accidental infection of workers or release into the surrounding community . CLIENT NAME / DATE Biosafety . Fundamental objective: – Containment of potentially harmful biological agents . Risk assessment: – Helps to assign the biosafety level that reduces to an absolute minimum the worker’s exposure to agents, their risk of an LAI (lab associated infection), and potential impact on the community and the environment CLIENT NAME / DATE Biosafety Levels (BSLs) . Combinations of lab practices and techniques, safety equipment, and laboratory facilities . Appropriate level determined by risk assessment . Specifically appropriate for: – Organism in use – Operations performed in the laboratory – Known or suspected routes of infection CLIENT NAME / DATE Determining BSLs . -
2019 Biodefense Public Report Implementation of the National Biodefense Strategy PREFACE
2019 Biodefense Public Report Implementation of the National Biodefense Strategy PREFACE The National Biodefense Strategy (NBS or the Strategy) was released on September 18, 2018 and guides the U.S. government’s efforts to reduce the risk of, prepare for, respond to, and recover from biological incidents, whether naturally occurring, deliberate, or accidental in origin. National Security Presidential Memorandum-14 (NSPM-14) directs implementation of the Strategy, including the development of this Biodefense Public Report. This report does not primarily address activities related to the coronavirus disease 2019 (COVID-19) pandemic because the data collection period concluded well before the HHS Secretary’s declaration of a public health emergency regarding the COVID-19 pandemic. Therefore, the content of this report is diverse and highlights some of the efforts across the U.S. government to address all biological threats. Development of this report followed the timeline laid out in NSPM-14. Work began among federal departments and agencies to collect biodefense data in late 2018, the first year to capture biodefense programs and activities across the federal government, and continued through the first half of 2019. This report describes a sampling of specific achievements and programs undertaken by federal agencies that reduce the risk of biological threats to the American people. In addition to the specific programs captured here, many other activities continue to be implemented across the federal government to protect the United States from a wide range of biological threats. Some of the efforts that have been described within this report, and many activities that have not been reported here, support the ongoing COVID-19 response. -
DHS Biowatch Program
CASE STUDY: DEPARTMENT OF HOMELAND SECURITY BIOWATCH PROGRAM Overview: The Department of Homeland Security (DHS) has established the BioWatch Program as a partnership between federal, state and local governments to counter terrorism in the United States. This Program serves an early detection system that provides continuous monitoring for the aerosol release of biological agents 24 hours a day, 7 days a week and 365 days a year in over 30 major population centers. The Program was developed by the Weapons of Mass Destruction and BioDefense Early Detection Division within Department of Homeland Security (DHS) in conjunction with the Environmental Protection Agency, the Centers for Disease Control Laboratory Response Network and other partners. At the heart of the Program is a team composed of field, laboratory, and public health personnel respon- sible for daily collection and testing of air samples, providing analysis, result reporting and emergency response activities. Air sample filters are collected daily on a 24-hour collection cycle and transported to a BioWatch laboratory within the Laboratory Response Network (LRN) for analysis. Business Challenge: DHS sought a prime contractor to manage all aspects of the BioWatch Program. The role of the prime contractor was designed around the mission, goals and objectives of the Program including: ◆ Manage the staffing of the BioWatch Program locations - ◆ Provide Program management 126 scientific staff across 28 laboratories in 32 major metro- ◆ Maintain existing equipment and supplies at all -
Clinical Laboratory Preparedness and Response Guide
TABLE OF CONTENTS Table of Contents ...................................................................................................................................................................................... 2 State Information ....................................................................................................................................................................................... 7 Introduction .............................................................................................................................................................................................. 10 Laboratory Response Network (LRN) .......................................................................................................................................... 15 Other Emergency Preparedness Response Information: .................................................................................................... 19 Radiological Threats ......................................................................................................................................................................... 21 Food Safety Threats .......................................................................................................................................................................... 25 BioWatch Program ............................................................................................................................................................................ 27 Bio Detection Systems -
Agricultural Bioterrorism
From the pages of Recent titles Agricultural Bioterrorism: A Federal Strategy to Meet the Threat Agricultural in the McNair MCNAIR PAPER 65 Bioterrorism: Paper series: A Federal Strategy to Meet the Threat 64 The United States ignores the The Strategic Implications of a Nuclear-Armed Iran Agricultural potential for agricultural bioter- Kori N. Schake and rorism at its peril. The relative Judith S. Yaphe Bioterrorism: ease of a catastrophic bio- weapons attack against the 63 A Federal Strategy American food and agriculture All Possible Wars? infrastructure, and the devastat- Toward a Consensus View of the Future Security to Meet the Threat ing economic and social conse- Environment, 2001–2025 quences of such an act, demand Sam J. Tangredi that the Nation pursue an aggres- sive, focused, coordinated, and 62 stand-alone national strategy to The Revenge of the Melians: Asymmetric combat agricultural bioterrorism. Threats and the Next QDR The strategy should build on Kenneth F. McKenzie, Jr. counterterrorism initiatives already underway; leverage exist- 61 ing Federal, state, and local pro- Illuminating HENRY S. PARKER grams and capabilities; and Tomorrow’s War Martin C. Libicki involve key customers, stake- PARKER holders, and partners. The U.S. 60 Department of Agriculture The Revolution in should lead the development of Military Affairs: this strategy. Allied Perspectives Robbin F. Laird and Holger H. Mey Institute for National Strategic Studies National Defense University About the Author NATIONAL DEFENSE UNIVERSITY President: Vice Admiral Paul G. Gaffney II, USN Henry S. Parker is National Program Leader for Aquaculture at the Vice President: Ambassador Robin Lynn Raphel Agricultural Research Service in the U.S. -
Eb117/2006/Rec/2
EB117/2006/REC/2 WORLD HEALTH ORGANIZATION EXECUTIVE BOARD 117TH SESSION GENEVA, 23-27 JANUARY 2006 SUMMARY RECORDS GENEVA 2006 ABBREVIATIONS Abbreviations used in WHO documentation include the following: ACHR – Advisory Committee on Health PAHO – Pan American Health Research Organization ASEAN – Association of Southeast Asian UNAIDS – Joint United Nations Programme Nations on HIV/AIDS CEB – United Nations System Chief UNCTAD – United Nations Conference on Executives Board for Trade and Development Coordination (formerly ACC) UNDCP – United Nations International CIOMS – Council for International Drug Control Programme Organizations of Medical UNDP – United Nations Development Sciences Programme FAO – Food and Agriculture UNEP – United Nations Environment Organization of the United Programme Nations UNESCO – United Nations Educational, IAEA – International Atomic Energy Scientific and Cultural Agency Organization IARC – International Agency for UNFPA – United Nations Population Fund Research on Cancer UNHCR – Office of the United Nations ICAO – International Civil Aviation High Commissioner for Refugees Organization UNICEF – United Nations Children’s Fund IFAD – International Fund for UNIDO – United Nations Industrial Agricultural Development Development Organization ILO – International Labour UNRWA – United Nations Relief and Works Organization (Office) Agency for Palestine Refugees in IMF – International Monetary Fund the Near East IMO – International Maritime WFP – World Food Programme Organization WIPO – World Intellectual Property -
“Defending the Homeland from Bioterrorism: Are We Prepared?”
2223 West Loop South Umair A. Shah, M.D., M.P.H. Houston, Texas 77027 Executive Director Tel: (713) 439-6000 Fax: (713) 439-6080 “Defending the Homeland from Bioterrorism: Are We Prepared?” Testimony of Umair A. Shah, MD, MPH Executive Director, Harris County Public Health, TX Past-President, National Association of County and City Health Officials Before the House Homeland Security Committee Subcommittee on Emergency Preparedness, Response, & Recovery October 17, 2019 I would like to thank Chairman Thompson, Ranking Member Rogers, Subcommittee Chairman Payne, Ranking Member King, and members of the committee for the opportunity to testify today on behalf of local health departments and public health emergency responders across the country. My name is Dr. Umair Shah, and I am the Executive Director for Harris County Public Health (HCPH) and the Local Health Authority for Harris County, Texas. Harris County is the third most populous county in the United States with 4.7 million people and is home to the nation’s 4th largest city, Houston. I am a Past President and former Board Member of NACCHO, the National Association of County and City Health Officials. NACCHO is the voice of the nearly 3,000 local health departments (LHDs) across the country. I am also a Past President and current Board Member of TACCHO, the Texas Association of City and County Health Officials, which represents approximately 45 LHDs across Texas. As background, Harris County is the most culturally diverse and one of the fastest growing metropolitan areas in the U.S. and home to the world’s largest medical complex, the Texas Medical Center, one of the nation’s busiest ports, the Port of Houston, and two of the nation’s busiest international airports. -
1 Hearing of the Subcommittee on Emergency Preparedness
Hearing of the Subcommittee on Emergency Preparedness, Response and Recovery, Committee on Homeland Security, U.S. House of Representatives “Defending the Homeland from Bioterrorism: Are We Prepared?” October 17, 2019 Statement for the Record Asha M. George, DrPH Executive Director, Bipartisan Commission on Biodefense Chairman Payne, Ranking Member King, and Members of the Subcommittee: Thank you for your invitation to provide the perspective of the Bipartisan Commission on Biodefense. On behalf of our Commission – and as a former Subcommittee Staff Director and senior professional staff for this Committee – I am glad to have the opportunity today to discuss our findings and recommendations with respect to biological terrorism and national defense against biological threats. Our Commission assembled in 2014 to examine the biological threat to the United States and to develop recommendations to address gaps in national biodefense. Former Senator Joe Lieberman and former Secretary of Homeland Security and Governor Tom Ridge co- chair the Commission, and are joined by former Senate Majority Leader Tom Daschle, former Representative Jim Greenwood, former Homeland Security Advisor Ken Wainstein, and former Homeland Security and Counter Terrorism Advisor Lisa Monaco. Our commissioners possess many years of experience with national and homeland security. In October 2015, the Commission released its first report, A National Blueprint for Biodefense: Major Reform Needed to Optimize Efforts. Shortly thereafter, we presented our findings and recommendations to this Committee. We made 33 recommendations with 87 associated short-, medium-, and long-term programmatic, legislative, and policy action items. If implemented, these would improve federal efforts across the spectrum of biodefense activities – prevention, deterrence, preparedness, detection and surveillance, response, attribution, recovery, and mitigation. -
Biosafety and Biosecurity Requirements for Orientia Spp
Blacksell et al. BMC Infectious Diseases (2019) 19:1044 https://doi.org/10.1186/s12879-019-4653-4 DEBATE Open Access Biosafety and biosecurity requirements for Orientia spp. diagnosis and research: recommendations for risk-based biocontainment, work practices and the case for reclassification to risk group 2 Stuart D. Blacksell1,2,3* , Matthew T. Robinson2,3, Paul N. Newton2,3, Soiratchaneekorn Ruanchaimun1, Jeanne Salje1,2, Tri Wangrangsimakul1,2, Matthew D. Wegner4, Mohammad Yazid Abdad5, Allan M. Bennett6, Allen L. Richards7, John Stenos8 and Nicholas P. J. Day1,2 Abstract Scrub typhus is an important arthropod-borne disease causing significant acute febrile illness by infection with Orientia spp. Using a risk-based approach, this review examines current practice, the evidence base and regulatory requirements regarding matters of biosafety and biosecurity, and presents the case for reclassification from Risk Group 3 to Risk Group 2 along with recommendations for safe working practices of risk-based activities during the manipulation of Orientia spp. in the laboratory. We recommend to reclassify Orientia spp. to Risk Group 2 based on the classification for RG2 pathogens as being moderate individual risk, low community risk. We recommend that low risk activities, can be performed within a biological safety cabinet located in a Biosafety Level (BSL) 2 core laboratory using standard personal protective equipment. But when the risk assessment indicates, such as high concentration and volume, or aerosol generation, then a higher biocontainment level is warranted. For, the majority of animal activities involving Orientia spp., Animal BSL 2 (ABSL2) is recommended however where high risk activities are performed including necropsies, Animal BSL (ABSL3) is recommended. -
Biosecurity: a Comprehensive Action Plan Center for American Progress
Center for American Progress Biosecurity A Comprehensive Action Plan Andrew J. Grotto Jonathan B. Tucker Progressive Ideas for a Strong, Just, and Free America Biosecurity: A Comprehensive Action Plan Center for American Progress Biosecurity A Comprehensive Action Plan Andrew J. Grotto and Jonathan B. Tucker June 2006 After Guantanamo: A Special Tribunal for International Terrorist Suspects 1 Biosecurity: A Comprehensive Action Plan Center for American Progress Table of Contents EXECUTIVE SUMMARY i BIOLOGICAL THREATS FACING THE UNITED STATES 1 PREVENTING BIO-CATASTROPHES: THE NEED FOR A GLOBAL APPROACH 9 PREVENTING THE MISUSE OF THE LIFE SCIENCES 9 RECOMMENDATIONS STRENGTHENING BIOLOGICAL DISARMAMENT MEASURES 14 RECOMMENDATIONS 8 CONTAINING DISEASE OUTBREAKS: AN INTEGRATED PUBLIC HEALTH STRATEGY 21 TIMELY DETECTION OF OUTBREAKS 22 RECOMMENDATIONS 0 RAPID CONTAINMENT OF OUTBREAKS 32 RECOMMENDATIONS 5 DEFENDING AGAINST BIOLOGICAL THREATS: AN INTEGRATED RESEARCH STRATEGY 37 REFORMING THE DRUG DEVELOPMENT PROCESS 38 RECOMMENDATIONS 41 RATIONALIZING BIODEFENSE SPENDING 42 RECOMMENDATIONS 44 GLOSSARY 47 Biosecurity: A Comprehensive Action Plan ACKNOWLEDGMENTS The authors are deeply grateful to the following individuals for their valuable comments and criticisms on earlier drafts of this report: Bob Boorstin, Joseph Cirincione, P. J. Crowley, Richard Ebright, Gerald L. Epstein, Trevor Findlay, Brian Finlay, Elisa D. Harris, David Heyman, Ajey Lele, Dan Matro, Caitriona McLeish, Jonathan Moreno, Peter Ogden, Alan Pearson, Michael Schiffer, Laura Segal, and Bradley Smith. 4 Center for American Progress Executive Summary iological weapons and infectious diseases share several fundamental characteristics that the United States can leverage to counter both Bof these threats more effectively. Both a bioweapons attack and a natural pandemic, such as avian flu, can be detected in similar ways, and the effectiveness of any response to an outbreak of infectious disease, whether natural or caused deliberately by terrorists, hinges on the strength of the U.S.