Fungi Utilizing Keratinous Substrates
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Review of Oxepine-Pyrimidinone-Ketopiperazine Type Nonribosomal Peptides
H OH metabolites OH Review Review of Oxepine-Pyrimidinone-Ketopiperazine Type Nonribosomal Peptides Yaojie Guo , Jens C. Frisvad and Thomas O. Larsen * Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Building 221, DK-2800 Kgs. Lyngby, Denmark; [email protected] (Y.G.); [email protected] (J.C.F.) * Correspondence: [email protected]; Tel.: +45-4525-2632 Received: 12 May 2020; Accepted: 8 June 2020; Published: 15 June 2020 Abstract: Recently, a rare class of nonribosomal peptides (NRPs) bearing a unique Oxepine-Pyrimidinone-Ketopiperazine (OPK) scaffold has been exclusively isolated from fungal sources. Based on the number of rings and conjugation systems on the backbone, it can be further categorized into three types A, B, and C. These compounds have been applied to various bioassays, and some have exhibited promising bioactivities like antifungal activity against phytopathogenic fungi and transcriptional activation on liver X receptor α. This review summarizes all the research related to natural OPK NRPs, including their biological sources, chemical structures, bioassays, as well as proposed biosynthetic mechanisms from 1988 to March 2020. The taxonomy of the fungal sources and chirality-related issues of these products are also discussed. Keywords: oxepine; nonribosomal peptides; bioactivity; biosynthesis; fungi; Aspergillus 1. Introduction Nonribosomal peptides (NRPs), mostly found in bacteria and fungi, are a class of peptidyl secondary metabolites biosynthesized by large modularly organized multienzyme complexes named nonribosomal peptide synthetases (NRPSs) [1]. These products are amongst the most structurally diverse secondary metabolites in nature; they exhibit a broad range of activities, which have been exploited in treatments such as the immunosuppressant cyclosporine A and the antibiotic daptomycin [2,3]. -
Discussions on Fungal Taxonomy and Nomenclature of Allergic Fungal Rhinosinusitis
Romanian Journal of Rhinology, Vol. 3, No. 11, July - September 2013 LITERATURE REVIEW Discussions on fungal taxonomy and nomenclature of allergic fungal rhinosinusitis Florin-Dan Popescu Department of Allergology, “Nicolae Malaxa” Clinical Hospital, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania ABSTRACT There is a significant debate regarding the role of fungi in chronic rhinosinusitis and whether allergic fungal rhinosi- nusitis truly represents an allergic subtype. The diverse nomenclature and heterogeneous taxonomy of fungi involved in the etiopathogenesis of this entity is important to be discussed in order to clarify the organisms detected and in- volved in this complex disease. KEYWORDS: fungi, allergic fungal rhinosinusitis INTRODUCTION flammatory cascade in AFRS is a multifunctional event, requiring the simultaneous occurrence of IgE- Fungal diseases of the nose and sinuses include a mediated sensitivity, specific T-cell HLA receptor ex- diverse spectrum of disease1. Although confusion pression and exposure to specific fungi4. Early recog- exists regarding fungal rhinosinusitis (FRS) classifi- nition of AFRS may be facilitated by screening pa- cation, a commonly accepted system divides FRS into tients with polypoid chronic rhinosinusitis or CRS invasive and noninvasive diseases based on histo- with nasal polyps (CRSwNP) patients for serum spe- pathological evidence of tissue invasion by fungi. cific IgE to molds5. Such specific IgE antibodies are The noninvasive diseases include saprophytic fungal also detectable in nasal lavage fluid and eosinophilic infestation, fungal ball and fungus-related eosinophi- mucin. Sinus mucosa homogenates may be assessed lic FRS (EFRS) that includes allergic fungal rhinosi- for IgE localization by immunohistochemistry and nusitis (AFRS). for antigen-specific IgE to fungal antigens by fluores- cent enzyme immunoassay6. -
Molecular Identification of Fungi
Molecular Identification of Fungi Youssuf Gherbawy l Kerstin Voigt Editors Molecular Identification of Fungi Editors Prof. Dr. Youssuf Gherbawy Dr. Kerstin Voigt South Valley University University of Jena Faculty of Science School of Biology and Pharmacy Department of Botany Institute of Microbiology 83523 Qena, Egypt Neugasse 25 [email protected] 07743 Jena, Germany [email protected] ISBN 978-3-642-05041-1 e-ISBN 978-3-642-05042-8 DOI 10.1007/978-3-642-05042-8 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2009938949 # Springer-Verlag Berlin Heidelberg 2010 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Cover design: WMXDesign GmbH, Heidelberg, Germany, kindly supported by ‘leopardy.com’ Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com) Dedicated to Prof. Lajos Ferenczy (1930–2004) microbiologist, mycologist and member of the Hungarian Academy of Sciences, one of the most outstanding Hungarian biologists of the twentieth century Preface Fungi comprise a vast variety of microorganisms and are numerically among the most abundant eukaryotes on Earth’s biosphere. -
Taxonomy, Chemodiversity, and Chemoconsistency of Aspergillus, Penicillium, and Talaromyces Species
View metadata,Downloaded citation and from similar orbit.dtu.dk papers on:at core.ac.uk Dec 20, 2017 brought to you by CORE provided by Online Research Database In Technology Taxonomy, chemodiversity, and chemoconsistency of Aspergillus, Penicillium, and Talaromyces species Frisvad, Jens Christian Published in: Frontiers in Microbiology Link to article, DOI: 10.3389/fmicb.2014.00773 Publication date: 2015 Document Version Publisher's PDF, also known as Version of record Link back to DTU Orbit Citation (APA): Frisvad, J. C. (2015). Taxonomy, chemodiversity, and chemoconsistency of Aspergillus, Penicillium, and Talaromyces species. Frontiers in Microbiology, 5, [773]. DOI: 10.3389/fmicb.2014.00773 General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. • Users may download and print one copy of any publication from the public portal for the purpose of private study or research. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. MINI REVIEW ARTICLE published: 12 January 2015 doi: 10.3389/fmicb.2014.00773 Taxonomy, chemodiversity, and chemoconsistency of Aspergillus, Penicillium, and Talaromyces species Jens C. Frisvad* Section of Eukaryotic Biotechnology, Department of Systems Biology, Technical University of Denmark, Kongens Lyngby, Denmark Edited by: Aspergillus, Penicillium, and Talaromyces are among the most chemically inventive of Jonathan Palmer, United States all fungi, producing a wide array of secondary metabolites (exometabolites). -
Identification of Fungi Storage Types by Sequencing Method
Zh. T. Abdrassulova et al /J. Pharm. Sci. & Res. Vol. 10(3), 2018, 689-692 Identification of Fungi Storage Types by Sequencing Method Zh. T. Abdrassulova, A. M. Rakhmetova*, G. A. Tussupbekova#, Al-Farabi Kazakh national university, 050040, Republic of Kazakhstan, Almaty, al-Farabi Ave., 71 *Karaganda State University named after the academician E.A. Buketov #A;-Farabi Kazakh National University, 050040, Republic of Kazakhstan, Almaty, al0Farabi Ave, 71 E. M. Imanova, Kazakh State Women’s Teacher Training University, 050000, Republic of Kazakhstan, Almaty, Aiteke bi Str., 99 M. S. Agadieva, R. N. Bissalyyeva Aktobe regional governmental university named after K.Zhubanov, 030000, Republic of Kazakhstan, Аktobe, A. Moldagulova avenue, 34 Abstract With the use of classical identification methods, which imply the identification of fungi by cultural and morphological features, they may not be reliable. With the development of modern molecular methods, it became possible to quickly and accurately determine the species and race of the fungus. The purpose of this work was to study bioecology and refine the species composition of fungi of the genus Aspergillus, Penicillium on seeds of cereal crops. The article presents materials of scientific research on morphological and molecular genetic peculiarities of storage fungi, affecting seeds of grain crops. Particular attention is paid to the fungi that develop in the stored grain. The seeds of cereals (Triticum aestivum L., Avena sativa L., Hordeum vulgare L., Zea mays L., Oryza sativa L., Sorghum vulgare Pers., Panicum miliaceum L.) were collected from the granaries of five districts (Talgar, Iliysky, Karasai, Zhambul, Panfilov) of the Almaty region. The pathogens of diseases of fungal etiology were found from the genera Penicillium, Aspergillus influencing the safety, quality and safety of the grain. -
Paecilomyces Variotii Xylanase Production, Purification and Characterization with Antioxidant Xylo-Oligosaccharides Production
www.nature.com/scientificreports OPEN Paecilomyces variotii xylanase production, purifcation and characterization with antioxidant xylo‑oligosaccharides production Asmaa Abdella1, Samah Ramadan2, Ragaa A. Hamouda3,4, Amna A. Saddiq5, Nuha M. Alhazmi5 & Mahmoud A. Al‑Saman1* Paecilomyces variotii xylanase was, produced in stirred tank bioreactor with yield of 760 U/mL and purifed using 70% ammonium sulfate precipitation and ultra‑fltration causing 3.29‑fold purifcation with 34.47% activity recovery. The enzyme purity was analyzed on sodium dodecyl sulfate– polyacrylamide gel electrophoresis (SDS‑PAGE) confrming its monomeric nature as single band at 32 KDa. Zymography showed xylan hydrolysis activity at the same band. The purifed enzyme had optimum activity at 60 °C and pH 5.0. The pH stability range was 5–9 and the temperature stability was up 70 °C. Fe2+and Fe3+ exhibited inhibition of xylanase enzyme while Cu2+, Ca2+, Mg2+ and Mn2+ stimulated its activity. Mercaptoethanol stimulated its activity; however, Na2‑EDTA and SDS inhibited its activity. The purifed xylanase could hydrolyze beechwood xylan but not carboxymethyl cellulose (CMC), avicel or soluble starch. Paecilomyces variotii xylanase Km and Vmax for beechwood were determined to be 3.33 mg/mL and 5555 U/mg, respectively. The produced xylanase enzyme applied on beech xylan resulted in diferent types of XOS. The antioxidant activity of xylo‑oligosaccharides increased from 15.22 to 70.57% when the extract concentration was increased from 0.1 to 1.5 mg/ mL. The enzyme characteristics and kinetic parameters indicated its high efciency in the hydrolysis of xylan and its potential efectiveness in lignocellulosic hydrolysis and other industrial application. -
Mining of Cryptic Secondary Metabolism in Aspergillus
Downloaded from orbit.dtu.dk on: Oct 10, 2021 Mining of Cryptic Secondary Metabolism in Aspergillus Guo, Yaojie Publication date: 2020 Document Version Publisher's PDF, also known as Version of record Link back to DTU Orbit Citation (APA): Guo, Y. (2020). Mining of Cryptic Secondary Metabolism in Aspergillus. DTU Bioengineering. General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. Users may download and print one copy of any publication from the public portal for the purpose of private study or research. You may not further distribute the material or use it for any profit-making activity or commercial gain You may freely distribute the URL identifying the publication in the public portal If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Mining of Cryptic Secondary Metabolism in Aspergillus O O O N R HN O N N N O O O OH OH O O OH OH OH O OH O OH OH OH OH HO O OH OH O OH OH OH O Yaojie Guo PhD Thesis Department of Biotechnology and Biomedicine Technical University of Denmark September 2020 Mining of Cryptic Secondary Metabolism in Aspergillus Yaojie Guo PhD Thesis Department of Biotechnology and Biomedicine Technical University of Denmark September 2020 Supervisors: Professor Thomas Ostenfeld Larsen Professor Uffe Hasbro Mortensen Preface This thesis is submitted to the Technical University of Denmark (Danmarks Tekniske Universitet, DTU) in partial fulfillment of the requirements for the Degree of Doctor of Philosophy. -
Characterization of Terrelysin, a Potential Biomarker for Aspergillus Terreus
Graduate Theses, Dissertations, and Problem Reports 2012 Characterization of terrelysin, a potential biomarker for Aspergillus terreus Ajay Padmaj Nayak West Virginia University Follow this and additional works at: https://researchrepository.wvu.edu/etd Recommended Citation Nayak, Ajay Padmaj, "Characterization of terrelysin, a potential biomarker for Aspergillus terreus" (2012). Graduate Theses, Dissertations, and Problem Reports. 3598. https://researchrepository.wvu.edu/etd/3598 This Dissertation is protected by copyright and/or related rights. It has been brought to you by the The Research Repository @ WVU with permission from the rights-holder(s). You are free to use this Dissertation in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you must obtain permission from the rights-holder(s) directly, unless additional rights are indicated by a Creative Commons license in the record and/ or on the work itself. This Dissertation has been accepted for inclusion in WVU Graduate Theses, Dissertations, and Problem Reports collection by an authorized administrator of The Research Repository @ WVU. For more information, please contact [email protected]. Characterization of terrelysin, a potential biomarker for Aspergillus terreus Ajay Padmaj Nayak Dissertation submitted to the School of Medicine at West Virginia University in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Immunology and Microbial Pathogenesis Donald H. Beezhold, -
Absidia Corymbifera
Publié sur INSPQ (https://www.inspq.qc.ca) Accueil > Expertises > Santé environnementale et toxicologie > Qualité de l’air et rayonnement non ionisant > Qualité de l'air intérieur > Compendium sur les moisissures > Fiches sur les moisissures > Absidia corymbifera Absidia corymbifera Absidia corymbifera [1] [2] [3] [4] [5] [6] [7] Introduction Laboratoire Métabolites Problèmes de santé Milieux Diagnostic Bibliographie Introduction Taxonomie Règne Fungi/Metazoa groupe Famille Mucoraceae (Mycocladiaceae) Phylum Mucoromycotina Genre Absidia (Mycocladus) Classe Zygomycetes Espèce corymbifera (corymbiferus) Ordre Mucorales Il existe de 12 à 21 espèces nommées à l’intérieur du genre Absidia, selon la taxonomie utilisée {1056, 3318}; la majorité des espèces vit dans le sol {431}. Peu d’espèces sont mentionnées comme pouvant être trouvées en environnement intérieur {2694, 1056, 470}. Absidia corymbifera, aussi nommé Absidia ramosa ou Mycocladus corymbiferus, suscite l’intérêt, particulièrement parce qu’il peut être trouvé en milieu intérieur et qu’il est associé à plusieurs problèmes de santé. Même si l’espèce Absidia corymbifera a été placée dans un autre genre (Mycocladus) par certains taxonomistes, elle sera traitée dans ce texte comme étant un Absidia et servira d’espèce type d’Absidia. Absidia corymbifera est l’espèce d’Absidiala plus souvent isolée et elle est la seule espèce reconnue comme étant pathogène parmi ce genre, causant une zygomycose (ou mucoromycose) chez les sujets immunocompromis; il faut noter que ces zygomycoses sont souvent présentées comme une seule entité, étant donné que l’identification complète de l’agent n’est confirmée que dans peu de cas. Quelques-unes des autres espèces importantes d’Absidia sont : A. -
Development of Aspergillus Niger
Studies in Mycology 74 (March 2013) Development of Aspergillus niger Jan Dijksterhuis and Han Wösten, editors CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands An institute of the Royal Netherlands Academy of Arts and Sciences Development of Aspergillus niger STUDIES IN MYCOLOGY 74, 2013 Studies in Mycology The Studies in Mycology is an international journal which publishes systematic monographs of filamentous fungi and yeasts, and in rare occasions the proceedings of special meetings related to all fields of mycology, biotechnology, ecology, molecular biology, pathology and systematics. For instructions for authors see www.cbs.knaw.nl. EXECUTIVE EDITOR Prof. dr dr hc Robert A. Samson, CBS-KNAW Fungal Biodiversity Centre, P.O. Box 85167, 3508 AD Utrecht, The Netherlands. E-mail: [email protected] LAYOUT EDITOR Manon van den Hoeven-Verweij, CBS-KNAW Fungal Biodiversity Centre, P.O. Box 85167, 3508 AD Utrecht, The Netherlands. E-mail: [email protected] SCIENTIFIC EDITORS Prof. dr Dominik Begerow, Lehrstuhl für Evolution und Biodiversität der Pflanzen, Ruhr-Universität Bochum, Universitätsstr. 150, Gebäude ND 44780, Bochum, Germany. E-mail: [email protected] Prof. dr Uwe Braun, Martin-Luther-Universität, Institut für Biologie, Geobotanik und Botanischer Garten, Herbarium, Neuwerk 21, D-06099 Halle, Germany. E-mail: [email protected] Dr Paul Cannon, CABI and Royal Botanic Gardens, Kew, Jodrell Laboratory, Royal Botanic Gardens, Kew, Richmond, Surrey TW9 3AB, U.K. E-mail: [email protected] Prof. dr Lori Carris, Associate Professor, Department of Plant Pathology, Washington State University, Pullman, WA 99164-6340, U.S.A. E-mail: [email protected] Prof. -
Lists of Names in Aspergillus and Teleomorphs As Proposed by Pitt and Taylor, Mycologia, 106: 1051-1062, 2014 (Doi: 10.3852/14-0
Lists of names in Aspergillus and teleomorphs as proposed by Pitt and Taylor, Mycologia, 106: 1051-1062, 2014 (doi: 10.3852/14-060), based on retypification of Aspergillus with A. niger as type species John I. Pitt and John W. Taylor, CSIRO Food and Nutrition, North Ryde, NSW 2113, Australia and Dept of Plant and Microbial Biology, University of California, Berkeley, CA 94720-3102, USA Preamble The lists below set out the nomenclature of Aspergillus and its teleomorphs as they would become on acceptance of a proposal published by Pitt and Taylor (2014) to change the type species of Aspergillus from A. glaucus to A. niger. The central points of the proposal by Pitt and Taylor (2014) are that retypification of Aspergillus on A. niger will make the classification of fungi with Aspergillus anamorphs: i) reflect the great phenotypic diversity in sexual morphology, physiology and ecology of the clades whose species have Aspergillus anamorphs; ii) respect the phylogenetic relationship of these clades to each other and to Penicillium; and iii) preserve the name Aspergillus for the clade that contains the greatest number of economically important species. Specifically, of the 11 teleomorph genera associated with Aspergillus anamorphs, the proposal of Pitt and Taylor (2014) maintains the three major teleomorph genera – Eurotium, Neosartorya and Emericella – together with Chaetosartorya, Hemicarpenteles, Sclerocleista and Warcupiella. Aspergillus is maintained for the important species used industrially and for manufacture of fermented foods, together with all species producing major mycotoxins. The teleomorph genera Fennellia, Petromyces, Neocarpenteles and Neopetromyces are synonymised with Aspergillus. The lists below are based on the List of “Names in Current Use” developed by Pitt and Samson (1993) and those listed in MycoBank (www.MycoBank.org), plus extensive scrutiny of papers publishing new species of Aspergillus and associated teleomorph genera as collected in Index of Fungi (1992-2104). -
Phylogeny and Nomenclature of the Genus Talaromyces and Taxa Accommodated in Penicillium Subgenus Biverticillium
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Elsevier - Publisher Connector available online at www.studiesinmycology.org StudieS in Mycology 70: 159–183. 2011. doi:10.3114/sim.2011.70.04 Phylogeny and nomenclature of the genus Talaromyces and taxa accommodated in Penicillium subgenus Biverticillium R.A. Samson1, N. Yilmaz1,6, J. Houbraken1,6, H. Spierenburg1, K.A. Seifert2, S.W. Peterson3, J. Varga4 and J.C. Frisvad5 1CBS-KNAW Fungal Biodiversity Centre, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands; 2Biodiversity (Mycology), Eastern Cereal and Oilseed Research Centre, Agriculture & Agri-Food Canada, 960 Carling Ave., Ottawa, Ontario, K1A 0C6, Canada, 3Bacterial Foodborne Pathogens and Mycology Research Unit, National Center for Agricultural Utilization Research, 1815 N. University Street, Peoria, IL 61604, U.S.A., 4Department of Microbiology, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Közép fasor 52, Hungary, 5Department of Systems Biology, Building 221, Technical University of Denmark, DK-2800, Kgs. Lyngby, Denmark; 6Microbiology, Department of Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands. *Correspondence: R.A. Samson, [email protected] Abstract: The taxonomic history of anamorphic species attributed to Penicillium subgenus Biverticillium is reviewed, along with evidence supporting their relationship with teleomorphic species classified inTalaromyces. To supplement previous conclusions based on ITS, SSU and/or LSU sequencing that Talaromyces and subgenus Biverticillium comprise a monophyletic group that is distinct from Penicillium at the generic level, the phylogenetic relationships of these two groups with other genera of Trichocomaceae was further studied by sequencing a part of the RPB1 (RNA polymerase II largest subunit) gene.