Yeast Genetics Meeting • July 29–August 3, 2014 • University of Washington, Seattle For up-to-date information visit y.gsaconf.org
SCHEDULE AT-A-GLANCE 9:00 am–11:00 SUNDAY, AUGUST3 6:00 pm–12:00am 5:30 pm–5:45 4:00 pm–5:30 2:00 pm–3:30 10:30 am–12:00noon 8:30 am–10:00 SATURDAY, AUGUST2 7:30 pm–11:00 6:00 pm–7:30 4:00 pm–5:30 2:00 pm–3:30 11:15 am–12:00noon 10:30 am–11:15 8:30 am–10:00 FRIDAY, AUGUST1 7:30 pm–11:00 6:00 pm–7:30 3:15 pm–4:45 1:30 pm–3:00 10:30 am–12:00noon 8:30 am–10:00 THURSDAY, JULY31 7:30 pm–11:00 6:00 pm–7:30 4:00 pm–5:30 2:00 pm–3:30 11:15 am–12:00noon 10:30 am–11:15 8:30 am–10:00 WEDNESDAY, 8:15 pm–11:00 7:15 pm–8:15 7:00 pm–7:15 6:00 pm–7:00 TUESDAY, JULY29 JULY 30 Dinner Epigenetics andPost-TranscriptionalRegulation Next GenerationGenetics Jeremy Thorner, University ofCalifornia,Berkeley Lifetime AchievementAward Aging Chromosome Dynamics Poster Session2andExhibits GSA CareerDinner Dinner Advocacy Presentation • • • Workshops: Dissecting ComplexTraits Trafficking andCellularArchitecture Poster Session1andExhibits “How toGetPublished”Presentation Dinner of GeneralMedicalSciences,NIH Special PresentationbyJonLorsch,DirectoroftheNationalInstitute Temporal andSpatialControlofChromatin George Church,Harvard University Lee HartwellLecture Environmental SensingNetworks Cell CycleTransitions Opening Mixer Olga Troyanskaya, PrincetonUniversity Ira HerskowitzAwardLecture Welcome andOpeningRemarks First TimeAttendees Social Chair: Genomics andProteomics Conference Party Banquet – Elizabeth W. JonesAward forExcellence inEducationtoMalcolmCampbell Presentation ofEdward Novitski Prize toCharlieBoonePresentationof GSA Awards Yeast andHumanDisease New Technologies Chromosome RearrangementsandPolyploidy Spatial Relationships Poster Session3andExhibits Plenary andWorkshopforUndergraduateResearchers Computational ToolsatSGD Beyond Cerevisiae Corey Nislow
Winge-Lindegren Address,Anita Hopper,OhioStateUniversity
y.gsaconf.org HUB Grand Ballroom HUB, Room 250 Meany Theater Meany Theater Meany Theater Meany Theater Meany Theater Lobby Meany Theater Meany Theater Meany Theater Lobby Meany Theater Meany Theater HUB Grand Ballroom Meany Theater Meany Theater Meany Theater Meany Theater Meany Theater HUB Grand Ballroom HUB Den Meany Theater Meany Theater Meany Theater Meany Theater Meany Theater HUB Grand Ballroom HUB Den Kane HallRoom 210 Kane HallRoom 210 Kane HallRoom 220 Kane HallRoom 120 Meany Theater Meany Theater July 29–August 3,2014 PROGRAM BOOK Yeast GeneticsMeeting The GeneticsSocietyofAmericaConferences • University ofWashington, Seattle
Meeting July 29-August 3, 2014 – University of Washington, Seattle
Program Book
Conference Organizers Trisha Davis, Chair Mike Snyder, Co-chair
Program Committee Karen Arndt Leonid Kruglyak Dave Toczyski Sue Biggins Michael Lichten Phong Tran Orna Cohen-Fix Vicki Lundblad Olga Troyanskaya Liz Conibear Mike McMurray Toshi Tsukiyama Maitreya Dunham Yoshi Ohya Fred van Leeuwen Richard Gardner Steve Oliver Eric Weiss Tim Hughes Peter Stirling
Mobile website: http://y.gsaconf.org Follow the conference on Twitter: #YEAST14
Genetics Society of America 9650 Rockville Pike, Bethesda, Maryland 20814-3998 Telephone: (301) 634-7300 • Toll-free: (866) 486-4363 • Fax: (301) 634-7079 E-mail: [email protected] • Website: genetics-gsa.org
The Genetics Society of America is pleased to be working with the yeast community to support the Yeast Genetics Meeting.
Founded in 1931, the Genetics Society of America (GSA) is a professional scientific society with more than 5,000 members worldwide working to deepen our understanding of the living world by advancing the field of genetics, from the molecular to the population level. GSA represents the collective interests of the genetics and model organism communities in advocating support for research, educating students and the public about the importance of genetics, and providing a respected and authoritative voice on genetic issues increasingly in the public eye.
GSA promotes research and fosters communication through a number of GSA conferences including regular meetings that focus on cross-cutting areas of genetics and particular model organisms including C. elegans, Chlamydomonas, ciliates, Drosophila, fungi, mice, Xenopus, yeast, and zebrafish.
GSA publishes two peer-edited scholarly journals: • GENETICS, which has published high quality original research across the breadth of the field since 1916, and • G3: Genes|Genomes|Genetics, an open-access journal launched in 2011 to disseminate high quality foundational research in genetics and genomics.
The Society has a deep commitment to fostering the next generation of scholars in the field, through providing career development activities and resources and offering travel grant programs including the GSA Undergraduate Travel Awards and DeLill Nasser Awards for Professional Development in Genetics.
2014 GSA Board of Directors Vicki Chandler, President • Jasper Rine, Vice-President • Michael Lynch, Immediate Past President • Anne M. Villeneuve, Secretary • Sue Jinks-Robertson, Treasurer • Angelika Amon • Lynn Cooley • Anna Di Rienzo • Sarah C.R. Elgin • Marnie E. Halpern • Lauren M. McIntyre • Mohamed A.F. Noor • Dmitri A. Petrov • John C. Schimenti • Deborah A. Siegele • Brenda J. Andrews, Editor-in-Chief, G3: Genes|Genomes|Genetics • Mark Johnston, Editor-in-Chief, GENETICS Trainee Advisory Representatives: Andrew Adrian, Krista Dobi, Kathleen Dumas
GSA Staff Adam P. Fagen, Executive Director • Mary Adams, Accounting/Membership • Raeka Aiyar, Communications & Engagement Manager • William Anderson, Web Designer • Suzy Brown, Senior Meetings Director • Sally Celia, Executive Assistant • Yimang Chen, Director of Information Technology • Tracey DePellegrin Connelly, Executive Editor • Cristy Gelling, Journals Assistant Editor • Ruth Isaacson, Assistant Managing Editor • Anne Marie Mahoney, Senior Meetings Director • Beth Ruedi, Director of Education & Professional Development • Wendy Scott, Editorial Office Assistant • Chuck Windle, Director of Finance & Administration • Hubert Zhang, IT Project Lead • Wujun Zhou, Web Developer
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Thank you to our Sponsors! Gold Sponsors
Silver Sponsors
Bronze Sponsors
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Table of Contents
Schedule of Events ...... 4
General Information ...... 6
GSA Education Programs ...... 8
Exhibits ...... 9
Platform and Workshop Session Listings ...... 10
Poster Session Listings ...... 19
Author Index ...... 49
Gene Index ...... 60
Notes ...... 65
Company Sponsored Ads ...... 69
University of Washington Map ...... 70
Please note: Abstracts published in this book should not be cited in bibliographies. Material contained herein should be treated as personal communication and should be cited as such only with the consent of the author.
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Schedule of Events
Tuesday, July 29 4:00 pm - 10:00 pm Registration Meany Theater Lobby 11:00 am – 5:00 pm GSA Trainee Boot Camp HUB, Room 340 5:00 pm – 6:30 pm GSA Education Special Interest Group Mixer/Pedagogy Workshop HUB, Room 337 6:00 pm - 7:00 pm First Time Attendees Social Meany Theater Lobby 7:00 pm - 7:15 pm Welcome and Opening Remarks Meany Theater Trisha Davis, Meeting Organizer, University of WA, Seattle Adam Fagen, Executive Director, Genetics Society of America Mark Johnston, Editor, GENETICS Brenda Andrews, Editor, G3: Genes, Genome, Genetics 7:15 pm - 8:15 pm Ira Herskowitz Award Lecture Meany Theater Olga Troyanskaya, Princeton University Introduction by Chad Myers 8:15 pm - 11:00 pm Opening Mixer Meany Theater Lobby Wednesday, July 30 7:30 am - 9:00 am Breakfast Lander Hall, Local Point 7:30 am – 5:30 pm Registration Meany Theater Lobby 8:30 am - 10:00 am Cell Cycle Transitions Meany Theater Chair: Mark Rose 10:30 am - 11:15 am Environmental Sensing Networks Meany Theater Chair: Brenda Andrews 11:15 am - 12:00 noon Lee Hartwell Lecture Meany Theater George Church, Harvard University Introduction by Mike Snyder 12:15 pm - 2:00 pm Lunch Lander Hall, Local Point 2:00 pm - 3:30 pm Temporal and Spatial Control of Chromatin Meany Theater Chair: Toshi Tsukiyama 4:00 pm - 5:30 pm Special Presentation by Jon Lorsch, Director of the National Meany Theater Institute of General Medical Sciences, NIH 6:00 pm - 7:30 pm Undergraduate Dinner HUB Den 6:00 pm - 7:30 pm Dinner HUB Den How to get Published Presentation HUB, Room 250 7:30 pm - 11:00 pm Poster Session 1 and Exhibits HUB Grand Ballroom Thursday, July 31 7:30 am - 9:00 am Breakfast Lander Hall, Local Point 8:30 am - 10:00 am Trafficking and Cellular Architecture Meany Theater Chair: Liz Conibear 10:30 am - 12:00 noon Dissecting Complex Traits Meany Theater Chair: Aimee Dudley 12:30 pm - 2:00 pm Lunch Lander Hall, Local Point 1:30 pm - 3:00 pm Workshops Beyond Cerevisiae Kane Hall, Room 120 Organizer: Judy Berman Computational Tools at SGD Kane Hall, Room 220 Organizer: Maria Costanzo Plenary and Workshop for Undergraduate Researchers Kane Hall, Room 210 Organizer: Beth Ruedi 4
Schedule of Events
3:15 pm – 4:45 pm Advocacy Presentation Kane Hall Room 210 Organizer: Adam Fagen 6:00 pm - 7:30 pm Dinner HUB Den GSA Career Dinner 7:30 pm – 11:00 pm Poster Session 2 and Exhibits HUB Grand Ballroom Friday, August 1 7:30 am - 9:00 am Breakfast Lander Hall, Local Point Dining 8:15 am - 5:30 pm Registration Meany Theater Lobby 8:30 am - 10:00 am Chromosome Dynamics Meany Theater Chair: Bonny Brewer 10:30 am - 11:15 am Aging Meany Theater Chair: Martha Cyert 11:15 am - 12:00 noon Lifetime Achievement Award Meany Theater Jeremy Thorner, University of California, Berkeley Introduction by Martha Cyert 12:15 pm - 2:00 pm Lunch Lander Hall, Local Point Dining 2:00 pm - 3:30 pm Next Generation Genetics Meany Theater Chair: Vivien Measday 4:00 pm - 5:30 pm Epigenetics and Post-Transcriptional Regulation Meany Theater Chair: Fred Winston 5:15 pm – 5:30 pm Tribute to Fred Sherman by Sue Liebman Meany Theater 6:00 pm - 7:30 pm Dinner HUB Den 7:30 pm - 11:00 pm Poster Session 3 and Exhibits HUB Grand Ballroom Saturday, August 2 7:30 am - 9:00 am Breakfast Lander Hall, Local Point 8:15 am - 12:00 noon Registration Meany Theater Lobby 8:30 am - 10:00 am Spatial Relationships Meany Theater Chair: Yoshi Ohya 10:30 am - 12:00 noon Chromosome Rearrangements and Polyploidy Meany Theater Chair: Audrey Gasch 2:00 pm - 3:30 pm New Technologies Meany Theater Chair: Sue Jaspersen 4:00 pm - 5:30 pm Yeast and Human Disease Meany Theater Chair: Jasper Rine 5:30 pm - 5:45 pm GSA Awards Meany Theater Presentation of Edward Novitski Prize to Charlie Boone Presentation of Elizabeth W. Jones Award for Excellence in Education to Malcolm Campbell 6:00 pm - 12:00 am Banquet, HUB Grand Ballroom Winge-Lindegren Address Anita Hopper, Ohio State University Introduction by Ben Hall Conference Party Sunday, August 3 9:00 am - 11:00 am Genomics and Proteomics Meany Theater Chair: Corey Nislow
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General Information
Registration Desk Hours:
Date Time Location Tuesday 4:00 pm – 10:00 pm Meany Theater Lobby Wednesday 7:30 am – 5:30 pm Meany Theater Lobby Thursday 8:00 am – 1:00 pm Meany Theater Lobby Friday 8:30 am – 5:30 pm Meany Theater Lobby Saturday 8:30 am – 4:00 pm Meany Theater Lobby
Mobile Web Site Bookmark the mobile website on your web enabled mobile device: ygsaconf.org
Follow the conference on Twitter: #YEAST14
Platform Presenter Instructions All platform authors should load their presentations onto the conference computer 45 minutes before the start of their session. A computer technician will be available to assist you in Meany Theater. Speakers should go into the theater, proceed to the front of the room and enter the door on the left to access the stage.
Posters All posters will be displayed in the Husky Union Building (HUB) Grand Ballroom. Presenters may begin posting their presentations on Wednesday, July 30 at 9:00 am and should be in place by 7:00 pm on Wednesday evening. Authors will present according to the following schedule:
Wednesday, July 30 Poster Session 1 Authors of even numbered “A” posters will present 7:30 pm – 8:30 pm Authors of odd numbered “A” posters will present 8:30 pm – 9:30 pm Open Viewing 9:30 pm – 11:00 pm
Thursday, July 31 Poster Session 2 Authors of even numbered “B” posters will present 7:30 pm – 8:30 pm Authors of odd numbered “B” posters will present 8:30 pm – 9:30 pm Open Viewing 9:30 pm – 11:00 pm
Friday, August 1 Poster Session 3 Authors of even numbered “C” posters will present 7:30 pm – 8:30 pm Authors of odd numbered “C” posters will present 8:30 pm – 9:30 pm Open Viewing – ALL POSTERS REMOVED by 11:15 pm 9:30 pm – 11:00 pm
Posters must be removed from their boards by 11:15 pm on Friday, August 1, to prepare the room for the dinner/party on Saturday night. POSTERS NOT RETRIEVED BY THIS TIME WILL BE DISCARDED. The GSA Administrative Office staff, Univ. of WA staff and the personnel taking down the boards will not be responsible for posters left by the authors.
Poster Legend
Cell Biology: 70A – 219C Global Analysis: 331A – 462C Chromosome Dynamics: 220A – 273C Academic Teaching: 463A – 465C Gene Expression: 274A – 330C Late Posters: 466 - 471
Photography Absolutely no photography is allowed in the poster display areas.
Messages and Notices Boards Boards for messages, employment notices and conferences are located in HUB Grand Ballroom.
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General Information
Meals
Breakfast 7:30 am – 9:00 am Lander Hall, Local Point Lunch 12:15 pm – 2:00 pm Lander Hall, Local Point Dinner 6:00 pm – 7:30 pm Husky Union Building, Den
Social Events
Tuesday First Time Attendees Social: Members of the Organizing Committee and other leaders in the field want to personally welcome you to the meeting. All first time attendees are invited for a cookies and coffee social in the Meany Hall Lobby at 6:00 pm.
Tuesday Opening Mixer: Catch up with old friends or meet new people at the Opening Mixer. Beer and wine from local microbrews and wineries will be served in addition to soft drinks and light appetizers.
Wednesday, Thursday and Friday evenings: A hosted bar will be open from 8:00 pm until 11:00 pm each evening in the Grand Ballroom. Be sure to stop by and visit the exhibits. Beer and wine from local microbrews and wineries will be served in addition to soft drinks and snacks.
Saturday evening: A banquet and party is planned from 6:00 pm until 12:30 am in the HUB Grand Ballroom. The GSA Poster Awards will be presented. Anita Hopper, University of Ohio, will present the Winge-Lindegren Address. Following the presentation, there will be a DJ and a hosted bar.
Annual Yeast Genetics Meeting Awards and Special Presentations The following awards and special presentations will be given:
Ira Herskowitz Award: Olga Troyanskaya, Princeton University Lee Hartwell Lecture: George Church, Harvard University Lifetime Achievement Award: Jeremy Thorner, University of California, Berkeley Winge-Lindegren Address: Anita Hopper, Ohio State University
How to Get Published: Process and Tips from the GSA Journals GENETICS and G3 Wednesday, July 30: 6:00 pm – 7:30 pm, HUB, Room 250 Join GENETICS and G3 journal editors as they discuss the ins and outs of publishing. Enjoy an opportunity to ask questions and learn more about publishing your articles. Topics may include: the peer-review process, open access, writing to get published, where and how your work can have the most impact, revisions and editing, ethical issues in publishing, journal data policies, and more. All are invited to attend, but students, postdocs, and newer faculty members may find the event most useful. After going through the buffet line in the Husky Den, participants should proceed to Room 250, with their dinner, for the presentation and to meet with the editors.
Advocacy Presentation Thursday, July 31, 3:15 pm – 4:45 pm, Kane Hall, Room 210 The GSA Executive Director will discuss the latest policy and legislative news affecting funding for NIH, describe why it is important for scientists to speak out about issues that affect their grants and research, and share tips for engaging in advocacy.
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GSA Education Opportunities
Tuesday, July 31
GSA Trainee Boot Camp (advance registration required) 11:00 am – 5:00 pm, HUB, Room 340 The boot camp, which is only open to graduate students and postdocs, will cover the following areas: finding funding, getting published, navigating academia and beyond traditional academia.
GSA Education Special Interest Group Mixer/Pedagogy Workshop 5:00 pm – 6:30 pm, HUB, Room 337 Faculty with a passion for genetics education are encouraged to attend this event, where they can mix and mingle with other educators. Current members of the Education SIG can catch up on actions taken by GSA with regards to the education initiative, and those who are not yet SIG members can learn about the Education SIG.
Wednesday, July 30
Genetics Conference Experience: 8:30 am – 12:30 pm The GSA Genetics Conference Experience provides students at local undergraduate institutions without strong research programs with the unique opportunity to observe distinguished career scientists present their current research in a conference setting. The students will receive a background lecture and participate in an interactive discussion before attending part of a plenary session. This program gives students a glimpse into the real world of genetics research and provides them the opportunity to learn about scientific research outside of a textbook, witness the communication of scientific research first-hand, and ideally will foster an interest in furthering their science education. Invitation-only.
Undergraduate Dinner 6:00 pm – 7:00 pm, HUB Den Undergraduate researchers attending the conference will network on their own forming a peer-group that will help provide lasting support for the remainder of the conference. After going through the buffet line, participants should go to the tables designated “Undergraduate Researchers”.
Thursday, August 2
Plenary and Workshop for Undergraduate Researchers 1:30 pm – 3:00 pm, Kane Hall, Room 210 Undergraduate conference attendees will attend a plenary session with two talks presented at a level appropriate for an undergraduate audience. Participants will then have a chance to talk to a panel of graduate students about applications, interviewing, admission, choosing a lab and quality of life in graduate school.
GSA Career Dinner 6:00 pm – 7:30 pm, HUB, Den The GSA Career Dinner is an excellent opportunity for undergraduates, graduate students, and postdoctoral fellows to have informal conversations with senior career scientists regarding the unique challenges and rewards of a scientific career. The dinner is organized by topic table. Topics may include: transition to independence, work- family balance, teaching at undergraduate institutions, non-academic careers for scientists, the job search, the postdoc search, etc. After going through the buffet line, participants should look for the topic tables.
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Exhibits
Exhibits will be open during the poster sessions in the HUB Grand Ballroom. Registrants are encouraged to visit the exhibits.
Carl Zeiss Microscopy microbioreactor systems like the RoboLector® , which Thornwood, NY offers even more bioprocessing capabilities at the Website: www.zeiss.com/microscopy microscale. Email: [email protected] SGD As the world's only manufacturer of light, X-ray and Stanford, CA electron/ion microscopes, ZEISS offers tailor-made Website: www.yeastgenome.org microscope systems for 3D imaging in biomedical Email: [email protected] research, life sciences and healthcare. A well-trained sales force, an extensive support infrastructure and a responsive The Saccharomyces Genome Database service team enable customers to use their ZEISS (SGD, http://www.yeastgenome.org) is the community microscopes to their full potential. resource for the budding yeast Saccharomyces cerevisiae, providing encyclopedic information about the yeast EMD Millipore Corporation genome and its genes, proteins, and other encoded Billerica, MA features. SGD is freely accessible to students, researchers, Website: www.emdmillipore.com and educators worldwide. Email: [email protected] Singer Instrument Company Formedium Somerset, United Kingdom Norkfolk, United Kingdom Website: www.singerinst.co.uk Website: www.Formedium.com Email: [email protected] Email: [email protected] Singer Instruments have been making scientific Specialist manufacturer of media for Yeast and Pombe instruments since 1934 and have brought speed, systems. Extensive ranges of all Drop- Out Supplements convenience, automation, reliability, technology and and formulations. Cost effective custom made Yeast ergonomics to yeast tetrad dissection to over 400 labs in media formulations. Guaranteed reliability with 50 countries. Singers Instruments also make the ROTOR outstanding value. For stock items delivery 3 days, HDA; a small, fast, high-density pinning and arraying custom made media delivery 6 days. robot for yeast, bacteria, and fungi research. Formedium- dedicated to research to optimize your results. Sunrise Science Products San Diego, CA Genetics Society of America Website: www.sunrisescience.com Bethesda, MD Email: [email protected] Website: www.genetics-gsa.org Email: [email protected] Sunrise Science Products manufactures hundreds of selective and non-selective yeast media formulations, and Come explore the resources and opportunities that GSA custom recipes for any organism are quickly produced. has to offer including education, career development and We are also proud to distribute yeast antibodies, products policy, meet members of the GSA staff and leadership; for protein expression in E. coli and unique magnetic and find out about publishing in GENETICS and G3: devices for efficient isolation of DNA , RNA and Genes|Genomes|Genetics. proteins.
M2P Labs Baesweiler, Germany Website: www.m2p-labs.com Email: [email protected] m2p-labs is a worldwide leading supplier of microbioreactor systems. The company focuses on microreactor systems and automated solutions for screening and bioprocess development. The BioLector® represents the core technology and based on this, m2p-labs also provides enhanced automated 9
Platform and Workshop Session Listings
Tuesday, July 29 7:15 pm – 8:15 pm Wednesday, July 30 8:30 am–10:00 am Meany Theater Meany Theater
Welcome and Opening Remarks Cell Cycle Transitions Chair: Mark Rose Trisha Davis, Meeting Organizer, University of Washington, Seattle 1 - 8:30 The structure of an Ndr/LATS kinase - Mob complex Adam Fagen, Executive Director reveals a novel kinase-coactivator system and Genetics Society of America substrate docking mechanism. Kyle Schneider, Gergõ Gógl, Brian Yeh, Nashida Alam, Alex Nguyen Ba, Alan Mark Johnston, GENETICS Editor and Moses, Csaba Hetenyi, Attila Reményi, Eric Weiss. Brenda Andrews, G3: Genes, Genome, Genetics Editor 2 - 8:45 Morphogenesis checkpoint kinase Swe1 is the executor Ira Herskowitz Award Lecture of lipolysis-dependent cell cycle progression. Sepp D. Kohlwein, Neha Chauhan, Myriam Visram. Olga Troyanskaya Princeton University 3 - 9:00 Compartmentalization of G1/S regulators allows Introduction by Chad Myers signaling information to traverse a switch-like transition. Andreas Doncic, Jan M. Skotheim.
4 - 9:15 Coordination of cell cycle-regulated gene expression by Cdk1. Benjamin Landry, Claudine Mapa, Heather Arsenault, Kristin Poti, Jennifer Benanti.
5 - 9:30 Understanding the Regulation, Composition and Function of P bodies and Stress Granules in Quiescent Cells. Khyati H. Shah, Paul K. Herman.
6 - 9:45 Novel pathways of transcription regulation during the transition from growth to quiescence. Shawna Miles, Amali P. Abeysinghe, Linda L. Breeden.
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Platform and Workshop Session Listings
Wednesday, July 30 10:30 am– 12:00 noon Wednesday, July 30 2:00 pm–3:30 pm Meany Theater Meany Theater
Environmental Sensing Networks Temporal and Spatial Control of Chromatin Chair: Brenda Andrews Chair: Toshi Tsukiyama
7 - 10:30 10 – 2:00 The inferred stress-activated signaling network from Heritable capture of heterochromatin dynamics in yeast: coordination, interconnectivity, and a novel Saccharomyces cerevisiae. Anne Dodson, Ryan Janke, NaCl network hub, Cdc14 phosphatase. Yi-Hsuan Ho,, Kathryn Sieverman, Jasper Rine. Deborah Chasman, Matthew MacGilvray, James Hose, Anna Merrill, Joshua Coon,, Mark Craven,, Audrey 11 – 2:15 Gasch,,. Dissecting the crosstalk between histone H2B ubiquitination and histone H3 methylation. Hanneke 8 - 10:45 Vlaming, Tibor van Welsem, Erik de Graaf, Maarten An integrated ‘omics approach to large-scale Altelaar, David Ontoso, Pedro San-Segundo, Fred van quantitative analysis of cellular metabolic regulation. Leeuwen. Sean Hackett, Vito Zanotelli, David Perlman, Joshua Rabinowitz. 12 - 2:30 Identification of a nucleosome patch required for 9 - 11:00 conserved histone modifications. Christine Cucinotta, The calcineurin signaling network evolves via Alexandria Young, Karen Arndt. conserved kinase-phosphatase modules that transcend substrate identity. Jagoree Roy, Aaron Goldman, Bernd 13 - 2:45 Bodenmiller, Stefanie Wanka, Christian Landry, Ruedi Mitochondrial feedback control through global H3K4 Aebersold,, Martha Cyert. demethylation. Maria Soloveychik, Mengshu Xu, Ashrut Narula, Adam Rosebrock, Amy Caudy, Marc Meneghini. Lee Hartwell Lecture 14 - 3:00 George Church Role of ATP-dependent chromatin remodeling enzyme Harvard University Fun30 in co-transcriptional pre-mRNA splicing. Qiankun Niu, Wei Wang, Boseon Byeon, Yong Li, Asim Introduction by Mike Snyder Bikas Das, Wei-Hua Wu.
15 – 3:15 Gene Loops Facilitate mRNA Export in Yeast. Badri Nath Singh, Michael Hampsey.
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Platform and Workshop Session Listings
Wednesday, July 30 4:00 pm–5:30 pm Thursday, July 31 10:30 am–12:00 noon Meany Theater Meany Theater
Special Presentation by Jon Lorsch, Director Dissecting Complex Traits of the National Institute of General Medical Chair: Aimee Dudley
Sciences, NIH 22 - 10:30 Higher-order epistasis between a mutation and four or more segregating variants generates a 'new' phenotype Thursday, July 31 8:30 am–10:00 am in a cross. Matthew Taylor, Ian Ehrenreich. Meany Theater 23 - 10:45 Trafficking and Cellular Architecture A quantitative study of whether the HSP90 chaperone Chair: Liz Conibear modulates robustness to new mutations, recombination, and standing variation in yeast. Kerry 16 - 8:30 A. Geiler-Samerotte, Mark L. Siegal. The budding yeast polo kinase, Cdc5, is a regulator of nuclear morphology. Alison D. Walters, Christopher K. 24 - 11:00 May, Emma Dauster, Bertrand P. Cinquin, Elizabeth A. Diversity across the Saccharomyces genus and the Smith, Carolyn A. Larabell, Orna Cohen-Fix genomic tools to tap it. Chris Todd Hittinger, William G. Alexander, Drew T. Doering, David Peris, Kayla 17 - 8:45 Sylvester, Diego Libkind, Paula Gonçalves, José Paulo Surveying the Inner Nuclear Membrane Landscape. Sampaio. Christine J. Smoyer, Jennifer Gardner, Sreenivasulu Santharam Katta, Brian Slaughter, Jay Unruh, Dan 25 - 11:15 Bradford, Scott McCroskey, Sue Jaspersen. High-throughput functional screening of driver mutations. Celia Payen, Anna Sunshine, Giang Ong, Wei Zhao, Maitreya Dunham. 18 - 9:00 SNAREs and the Dsl1 tethering complex mediate an 26 - 11:30 alternative, Sey1p-independent ER fusion pathway. Genetic influences on translation in yeast. Frank W. Jason V. Rogers, Conor McMahon, Anastasia , , ,, , Albert, Dale Muzzey , Jonathan S. Weissman , Leonid Baryshnikova , Michael Costanzo, Charles M. Boone , Kruglyak,,. Frederick M. Hughson, Mark D. Rose. 27 - 11:45 19 - 9:15 Analysis of transcription activation distance as a Plasma membrane localized KDEL receptors ensure polygenic trait in Saccharomyces cerevisiae. Caitlin endocytic entry and retrograde transport of a viral Reavey, Mark Hickman, David Botstein, Fred A/B toxin in yeast. B. Becker, A. Blum, D. Rammo, M. Winston. J. Schmitt.
20 - 9:30 Elucidating the architecture and function of the yeast exocyst complex. Mary Munson, Margaret Heider, Caroline Duffy, Zhanna Hakhverdyan, Raghav Kalia, Nicholas Farrall, Michael Rout, Adam Frost.
21 - 9:45 The molecular architecture of the Target Of Rapamycin Complex 2 reveals why it is insensitive to rapamycin. C. Gaubitz,, T. Maia de Olivera,, Manoël Prouteau,, A. Leitner, M. Karuppasamy, D. Rispal, S. Eltschinger, G. Robinson, G. Konstantinidou, S. Thore, R. Aebersold, R. Loewith,, C. Schaffitzel,
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Platform and Workshop Session Listings
Thursday, July 31 1:30 pm–3:00 pm Thursday, July 31 1:30 pm–3:00 pm Kane Hall, Room 120 Kane Hall, Room 220
Beyond Cerevisiae Computational Tools at SGD Chair: Judy Berman Chair: Maria Costanzo
Saccharomyces cerevisiae is arguably the most powerful In the Saccharomyces Genome Database workshop, we’ll eukaryotic model system for molecular genetics and be talking about ways that you can get more out of SGD. genomics. The increased accessibility of technologies such We’ll focus on our incredibly powerful tool, YeastMine, as whole genome sequencing has made analysis of closely that lets you ask virtually any question about yeast data. related and more distantly related species much more We’ll also discuss recent improvements to SGD, and have feasible. In this workshop, speakers will introduce the time for questions. organism or organisms they are studying and the reasons for studying them. They will then provide insights into the • S. cerevisiae Strains and Sequences types of studies they are performing, and highlight the results • they are obtaining, to better understand these organisms. We The Awesome Power of YeastMine will start with a focus on comparisons between the species • New Features Coming Soon to SGD and then highlight more distantly related organisms • Open Q&A including important human pathogens. Thursday, July 31 1:30 pm–3:00 pm 1:30 Kane Hall, Room 210 Comparative Genomics of Yeast Genome Conformation and Functional Annotation by Multiplexed Hi-C Ivan Plenary and Workshop for Undergraduate Liachko, Joshua Burton, Jay Shendure, Maitreya Researchers Dunham, Genome Sciences Chair: Beth Ruedi
1:45 Undergraduate conference attendees will attend a plenary Investigating reticulate evolution in the Saccharomyces session with two talks presented at a level appropriate for genus and repeating it for the bioethanol industry. David an undergraduate audience. Participants will then have a Peris Navarro, Kayla Sylvester, Maria Sardi, William chance to talk to a panel of graduate students about Alexander, Diego Libkind, Paula Gonçalves, José applications, interviewing, admission, choosing a lab and Sampaio, Lucas Parreiras, Trey Sato, Chris Hittinger. quality of life in graduate school.
2:00 Evolutionary genomics of ecological speciation in Thursday, July 31 3:15 pm–4:45 pm Saccharomyces paradoxus. Jean-Baptiste Leducq, Lou Kane Hall, Room 220 Nielly-Thibaut, Guillaume Charron, Christian Landry. Advocacy Presentation 2:15 Chair: Adam Fagen Genome-wide patterns of genetic variation reveal chromosome-scale heterogeneous evolution in a We will discuss the latest policy and legislative news protoploid yeast. Anne Friedrich, Paul Jung, Cyrielle affecting funding for NIH, describe why it is important Reisser, Gilles Fischer, Joseph Schacherer. for scientists to speak out about issues that affect their grants and research, and share tips for engaging in 2:30 advocacy. The development of molecular tools facilitates functional comparisons between Saccharomyces cerevisiae and the related pathogenic yeast Candida glabrata. Lauren Ames, Hsueh-lui Ho, Jane Usher and Ken Haynes.
2:45 A Tetraploid Intermediate Precedes Aneuploid Formation in Yeasts Exposed to Fluconazole. Benjamin Harrison, Maayan Bibi, Rebecca Pulver, Melanie Wellington, Jordan Hashemi, Guillermo Sapiro, Judith Berman. 13
Platform and Workshop Session Listings
Friday, August 1 8:30 am–10:00 am Friday, August 1 10:30 am–12:00 noon Meany Theater Meany Theater
Chromosome Dynamics Aging Chair: Bonny Brewer Chair: Martha Cyert
28 - 8:30 34 - 10:30 Mapping Recombination in Single Meiotic Cells An Asymmetric Competition for Protons Promotes Reveals that Tel1/ATM Controls the Positioning and Aging but Facilitates Rejuvenation. Kiersten A. Fate of DNA Double-Strand Breaks. Carol Anderson, Henderson, Adam L. Hughes, Daniel E. Gottschling. Ashwini Oke, Phoebe Yam, Jennifer Fung. Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA. 29 - 8:45 RAD51 and the DNA damage checkpoint are essential 35 - 10:45 for increased chromosome mobility after DNA damage The heterogeneity of peroxisomes in yeast. Sanjeev in diploid S. cerevisiae. Michael J. Smith, Fraulin Kumar,, Ida J. van der Klei, Joseph, Marina Ermakova, Ignacio Izeddin, Vincent Recamier,, Xavier Darzacq, Judith Mine-Hattab,,, Rodney 36 - 11:00 Rothstein. Translocation of cyclin C to the mitochondria mediates stress-induced fission and programmed cell 30 - 9:00 death. Randy S. Strich, Katrina F. Cooper. A combined genetic and biochemical analysis of yeast telomerase. Johnathan W. Lubin,, Timothy M. Tucey,, , Lisa Nguyen , Vicki Lundblad Lifetime Achievement Award
31 - 9:15 Jeremy Thorner, University of The FACT complex interacts with the E3 ubiquitin California, Berkeley ligase Psh1 to prevent ectopic localization of CENP-A. Gary M. Deyter, Sue Biggins. Introduction by Martha Cyert
32 - 9:30 Reconstitution of strong kinetochore attachments requires more than the microtubule binding components of the kinetochore. Emily M. Mazanka, Neil T. Umbreit, Alex Zelter, Daniel R. Gestaut, Charles L. Asbury, Trisha N. Davis.
33 - 9:45 Specialization of kinetochores for segregation of maternal and paternal chromosomes during meiosis I. Adele Marston, Eris Duro, Krishna Sarangapani, Nadine Vincenten, Yi Deng, Kwaku Opoku, Flavia de Lima Alves, Juri Rappsilber, Qiaozhen Ye, Kevin Corbett, Sue Biggins, Charles Asbury.
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Platform and Workshop Session Listings
Friday, August 1 2:00 pm–3:30 pm Friday, August 1 4:00 pm–5:30 pm Meany Theater Meany Theater
Next Generation Genetics Epigenetics and Post-Transcriptional Regulation Chair: Vivien Measday Chair: Fred Winston
37 - 2:00 Engineering of alcohol and stress tolerance traits in 43 - 4:00 Saccharomyces cerevisiae using a novel synthetic Intrinsically disordered proteins drive heritable biology approach for producing genetic diversity. epigenetic switches that transform the phenotypic Sabrina German, Biranchi N. Patra, Animesh Ray, Helge landscape of S. cerevisiae. Sohini Chakrabortee, James Zieler. Byers, Susan Lindquist, Daniel Jarosz.
38 - 2:15 44 - 4:15 Mapping genetic suppression interactions on a global , Cheaters Do Prosper: Reciprocal cheating drives scale. Jolanda van Leeuwen, Joseph Mellor , Guihong epigenetic switching of facultative multicellularity. Tan, Takafumi Yamaguchi, Anastasia Baryshnikova, Paul Sorna Kamara, Randal Halfmann. Bansal,, Michael Costanzo, Brenda Andrews,, Frederick ,, , Roth , Charles Boone . 45 - 4:30 The PUF Protein Puf3 Toggles the Translational Fate 39 - 2:30 of Bound mRNAs to Regulate Mitochondrial Toward a complete reference eukaryotic genetic Biogenesis. Chien-Der Lee, Benjamin Tu. interaction network. Benjamin VanderSluis, Michael , Costanzo , Elizabeth Koch, Carles Pons, Anastasia 46 - 4:45 Baryshnikova, Wen Wang, Matej Usaj,, Brenda J. , , Genome-wide screen identifies pathways that govern Andrews , Charles Boone , Chad L. Myers. tRNA splicing and intron turnover in Saccharomyces cerevisiae. Jingyan Wu, Yao Wan, Anita Hopper. 40 - 2:45 Global analysis of HAT and HDAC substrates in vivo. 47 - 5:00 David Paul Toczyski, Michael Downey. Heritable variation of mRNA decay rates in yeast. Jennifer M. Andrie, Jon Wakefield, Joshua M. Akey. 41 - 3:00 Protein localization re-patterning during DNA replication stress. Nikko P. Torres, Grant W. Brown. Tribute to Fred Sherman 42 - 3:15 High dimensional phenotyping reveals remarkable Given by Sue Liebman extent of haploinsufficiency in essential genes. Shinsuke Ohnuki, Yoshikazu Ohya.
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Platform and Workshop Session Listings
Saturday, August 2 8:30 am–10:00 am Saturday, August 2 10:30 am–12:00 noon Meany Theater Meany Theater
Spatial Relationships Chromosome Rearrangements and Polyploidy Chair: Yoshi Ohya Chair: Audrey Gasch
48 - 8:30 54 - 10:30 A Stable Quasi-Filamentous Growth Pattern in Protein based interference of Ty1 retrotransposition in Budding Yeast. Junwon Kim, Mark D. Rose. budding yeast: characterization of copy number control resistant mutants. J. A. Mitchell, A. Saha, Y. 49 - 8:45 Nishida, M. Larango, L. Wachsmuth, E. Talevich, N. Gradient tracking in yeast: role of Gβγ polarity. Kannan, D. J. Garfinkel. Allison McClure, Jayme Dyer, Maria Minakova, Timothy Elston, Daniel Lew 55 - 10:45 The impact of polyploidy on the rate and dynamics of 50 - 9:00 adaptation. Anna M. Selmecki, Yosef E. Maruvka, Spatial control of microtubule length and lifetime by Philip A. Richmond, Marie Guillet, Noam Shoresh, opposing stabilizing and destabilizing functions of Amber Sorenson, Subho De, Roy Kishony, Franziska Kinesin-8. Yusuke Fukuda, Anna Luchniak, Erin Michor, Robin Dowell, David Pellman. Murphy, Mohan Gupta. 56 - 11:00 51 - 9:15 Polyploidy drives population heterogeneity through Polarization of the Endoplasmic Reticulum by ER- random and stepwise chromosome loss. Meleah A. Septin Tethering. Jesse T. Chao, Andrew K. O. Wong, Hickman, Carsten Paulson, Judith Berman. Shabnam Tavassoli, Barry P. Young, Adam Chruscicki, Nancy N. Fang,, LeAnn J. Howe, Thibault Mayor,, 57 - 11:15 Leonard J. Foster,, Christopher J. R. Loewen Complex genetic interaction profiles reveal evolutionary fates of duplicated genes. Elena Kuzmin,, 52 - 9:30 Benjamin VanderSluis, Yiqun Chen, Raamesh Coordination between terminal septin subunits: both Deshpande, Matej Usaj, Alex Nguyen, Alan Moses, Cdc11 and Shs1 promote bud neck recruitment of the Michael Costanzo, Chad L. Myers, Brenda J. Andrews,, myosin II-binding factor Bni5. Gregory C. Finnigan, Charles Boone,. Julie Tagaki, Christina Cho, Elizabeth Booth, Jeremy Thorner. 58 - 11:30 Sexual conflicts and chromosome rearrangements 53 - 9:45 drive infertility. Sarah E. Zanders, Michael Eickbush, A cytosolic chaperone network mediates quality Jonathan Yu, JiWon Kang, Gerry Smith, Harmit Malik. control of higher-order septin assembly. C. Johnson, A. Weems, J. Brewer, J. Thorner, M. McMurray. 59 - 11:45 3D structure of yeast synthetic chromosomes. Heloise Muller,, Axel Cournac,, Romain Koszul,.
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Platform and Workshop Session Listings
Saturday, August 2 2:00 pm–3:30 pm Saturday, August 2 4:00 pm–5:30 pm Meany Theater Meany Theater
New Technologies Yeast and Human Disease Chair: Sue Jaspersen Chair: Jasper Rine
60 - 2:00 64 - 4:00 Towards in vivo NMR: NMR of prion fibrils at Quantifying the functional impact of all possible endogenous levels in cellular lysates. Kendra K. missense variants of BRCA1. Lea Starita, Jacob Frederick, Vladimir K. Michaelis,, Björn Corzilius,, Ta- Kitzman, Justin Gullingsrud, Jeffrey Parvin, Jay chung Ong,, Jacavone Angela,, Robert G. Griffin,, Susan Shendure, Stanley Fields,. Lindquist,,. 65 - 4:15 61 - 2:15 Using DNA Repair Mutants for Cancer Drug Structured metabolic response to cellular stress. Adam Discovery and Identifying Chemoresistance Targets. Rosebrock, Julia Hanchard,, Olga Zaslaver,, Chris Go,, Irene Ojini, Alison Gammie. Ying Zhang,, Amy Caudy,. 66 - 4:30 2:30 Towards humanizing budding yeast. Aashiq H. Judit Villen, Title unavailable at time of print Kachroo, Jon M. Laurent, Christopher Yellman, Edward M. Marcotte. 63 - 2:45 The use of fluorescence cross-correlation spectroscopy 67 - 4:45 to assay information about protein complexes in yeast. Organelle deterioration with age: The limits of an Brian Slaughter, Jay Unruh, Christine Smoyer, Sue interconnected cellular system. Dan Gottschling. Jaspersen. 68 - 5:00 2:55 Orphan Diseases: Identifying Genes and ŠTULIPs: tunable, light-controlled interacting protein NovelTherapeutics to Enhance Treatment (IGNITE). tags for cell biology, Eric Weiss Christopher McMaster.
3:05 69 - 5:15 N-terminal Chromosome instability and synthetic cytotoxicity in An all-in-one yeast library - creating a new toolbox for yeast and cancer. Philip A. Hieter, Derek van Pel, studying the proteome. Uri Weill, Ido Yofe, Maya Hunter Li, Noushin Moshgabadi, Melanie Bailey, Nigel Schuldiner. O'Neil.
3:15 GSA Awards High level of chromosomal mosaicism in supposedly clonal yeast cell populations. Alexandre Gillet- Markowska, Gilles Fischer. Presentation of Edward Novitski Prize to Charlie Boone, University of Toronto
Presentation of Elizabeth W. Jones Award for Excellence in Education to Malcolm Campbell, Davidson College
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Platform and Workshop Session Listings
Sunday, August 3 9:00 am–11:00 pm Meany Theater
Genomics and Proteomics Chair: Corey Nislow
9:00 am Determination of in vivo RNA kinetics using RATE- seq. David Gresham
9:15 am Proteomic approach to predicting regulators of yeast response to 4MCHM. Jennifer Gallagher
9:30 am Profiling the RNA maturation landscape in yeast. John Aitchison
9:45 am Mapping the cellular response to small molecules using chemogenomic fitness signature, Guri Giaver
10:00 am A Chemical-Genetic Matrix Strategy for Directed Discovery of Small Molecule Synergizers. Mike Tyers
10:15 am Improving the yeast metabolic model using LOPIT proteomic data. Stephen Oliver
10:30 am Extensive diversity in the transcriptional output from the yeast genome. Lars Steinmetz
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Poster Session Listings
and Molecular Biology, University of Chicago, Chicago, IL Cell Biology: Cell cycle/Growth 60637, USA; 3) Department of Statistics, Harvard control/Metabolism University, Cambridge, MA 02138, USA; 4) FAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA. 70A Understanding the regulation of motor proteins in 78C cdc15-2 cells recovering from spindle damage. Beryl Parsing the many possible physiological roles of Augustine, Foong May Yeong. Dept of Biochemistry, trehalose in yeast. P. Gibney, A. Schieler, J. Chen, Y. Xu, Yong Loo Lin School of Medicine, National University of J. Rabinowitz, D. Botstein. Lewis-Sigler Institute, Singapore, Singapore. Princeton University, Princeton, NJ.
71B 79A Physiological impact of NAD(P)HX accumulation in Global analysis of molecular fluctuations associated yeast. Julia Becker-Kettern, Paul P. Jung, Carole L. with cell cycle progression in Saccharomyces cerevisiae. 1 1 2 2 1 Linster. Luxembourg Centre for Systems Biomedicine B. Grys , H. Friesen , O. Kraus , B. J. Frey , C. Boone , B. 1 (LCSB), University of Luxembourg, Esch-sur-Alzette, J. Andrews . 1) Donnelly Centre for Cellular and Luxembourg. Biomolecular Research, Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; 2) Electrical and Computer Engineering, University of Toronto, Toronto, 72C Ontario, Canada. A cell separation checkpoint ensures proper order of late cytokinetic events. Jennifer L. Brace, Matthew Doerfler, Eric L. Weiss. Molecular Biosciences, 80B Northwestern Univ, Evanston, IL. Untargeted metabolomics reveals the rate of secondary mutations causing metabolic phenotypes. Julia A. Hanchard1,2, Adam P. Rosebrock2, Amy A. Caudy1,2. 1) 73A Department of Molecular Genetics, University of Toronto, Respiro-fermentative differentiation in yeast colonies. 1 2 1 Toronto, Ontario, Canada; 2) Donnelly Center for Cellular Michal Cap , Libuse Vachova , Zdena Palkova . 1) and Biomolecular Research, University of Toronto, Department of Genetics and Microbiology, Faculty of Toronto, Ontario, Canada. Science, Charles University, 128 44 Prague, Czech Republic; 2) Institute of Microbiology of the ASCR, v.v.i., 142 20 Prague 4, Czech Republic. 81C Functions of genes typical of structured colony morphology. Otakar Hlavacek1, Vratislav Stovicek2, 74B Libuse Vachova1, Zdena Palkova2. 1) Laboratory of Cell Cell Cycle Regulation of Endocytic Vesicle Scission Biology, Institute of Microbiology, ASCR, v.v.i., 142 20 Apparatus during Mitotic Exit in Saccharomyces Prague 4, Czech Republic; 2) Department of Genetics and cerevisiae. Kaiquan Tan, Cheen Fei Chin, Foong May Microbiology, Faculty of Science, Charles University in Yeong. Biochemistry, National University of Singapore, Prague, 128 44 Prague 2, Czech Republic. Singapore.
82A 75C Investigating the role of CDK-mediated The metabolic response to acetic acid stress in phosphorylation of the bud neck-localized proteins Saccharomyces cerevisiae. Yachen Dong, Zhihua Jiao, Jin Bud3 and Bni4. Jennifer K. Hood-DeGrenier, Bharat Cai, Ruosi Fang, Qihe Chen. Department of Food Science Hans, Angeline Cloutier, Alyssa Geddis, Hanh Nguyen. and Nutrition, Zhejiang University, Hangzhou, China. Biology Department, Worcester State University, Worcester, MA. 76A A genetic selection to identify new components of the S. 83B cerevisiae RAM network. S. Edwards, J. Jansen, J. Brace, SUN Family Proteins Sun4p, Uth1p and Sim1p are E. Weiss. Molecular Biosciences, Northwestern University, efficiently secreted out of the Saccharomyces cerevisiae Evanston, IL. cells and regulated differently during development of yeast cultures. Evgeny Kuznetsov1, Helena Kucerova2, 77B Zdena Palkova1, Libuse Vachova2. 1) Department of Quantifying Condition-Dependent Intracellular Protein Genetics and Microbiology, Charles University in Prague, Levels Enables High-Precision Fitness Estimates. Kerry Czech Republic; 2) Institute of Microbiology of the ASCR. A. Geiler-Samerotte1, Tatsu Hashimoto3, Mike Dion4, Bogdan Budnik4, Edo Airoldi3, D. Allan Drummond2. 1)
Center for Genomics and Systems Biology, New York University, New York, NY; 2) Department of Biochemistry
19
Poster Session Listings
84C 92B The Npr2 complex regulates a metabolic switch that Roles of FMS1 (orf19.4589) and CBP1 (orf19.7323) controls TORC1 dependent proliferation during amino genes in the de novo beta-alanine synthesis pathway acid limited growth. Sunil Laxman, Benjamin Sutter, Lei from polyamines in Candida albicans. Ruvini U. Shi, Benjamin Tu. Biochemistry, UT Southwestern Pathirana1, Dhammika H. M. L. P. Navarathna2, Kenneth Medical Center, Dallas, TX. W. Nickerson1. 1) School of Biological Sciences, University of Nebraska - Lincoln, Lincoln, NE; 2) 85A Laboratory of Pathology, Center for Cancer Research, Role for alkaline ceramidase and its products sphingoid National Cancer Institute, National Institutes of Health, bases in the oxidative stress response. Jae Kyo Yi, Bethesda, Maryland. Ruijuan Xu, EunMi Jeong, Cungui Mao. The Department of Medicine and Cancer Center, Stony Brook University, 93C Stony Brook, NY. Revisiting the myth of trehalose in the heat shock response: The Tps1 protein, and not trehalose, 86B protected yeast cells from losing viability at high The unfolded protein response has a protective role in temperature. M. Petitjean, MA. Teste, JM. François, JL. yeast models of classic galactosemia. Evandro A. De- Parrou. Laboratoire d'Ingénierie des Systèmes Biologiques Souza, Felipe S. A. Pimentel, Caio M. Machado, Larissa S. et des Procédés, UMR-CNRS5504 & UMR-INRA 792 & Martins, Wagner S. da-Silva, Mónica Montero-Lomelí, INSA & Université de Toulouse, Toulouse, France. Claudio A. Masuda. Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, 94A Rio de Janeiro, RJ, Brazil. Revisiting the role of TPS1 encoding trehalose 6-P synthase in the regulation of yeast glycolysis. M. 87C Petitjean, A. Vax, MA. Teste, JL. Parrou, JM. François. Measurement of thiamine vitamers and ethanol/CO2 in Laboratoire d'Ingénierie des Systèmes Biologiques et des C. glabrata. Erin M. Neal, Christine L. Kerwin-Iosue, Procédés ,UMR-CNRS5504, UMR-INRA 792,INSA, Dennis Wykoff. Biology Department, Villanova Toulouse, France. University, Villanova, PA. 95B Specific histone residues mediate RTS1 rescue of gcn5Δ 88A 1,2 Identification of regulators of riboneogenesis by high- growth under stress. Emily L. Petty , Shannon M. Tomlinson1, Anne Lafon3, Bryce Mendelsohn4, Kristofor throughput metabolomic and expression screens. Yoomi 1 1 1,2 Oh1,2, Adam Rosebrock1, Amy Caudy1,2. 1) Donnelly Webb , Eric J. Bennett , Lorraine Pillus . 1) Division of Centre for Cellular and Biomolecular Research, University Biological Sciences, UCSD, La Jolla, CA; 2) Moores of Toronto, Toronto, Ontario, Canada; 2) Department of Cancer Center Institute, UCSD, La Jolla, CA; 3) Institut Molecular Genetics, University of Toronto, Toronto, Curie, Paris; 4) Department of Pediatrics, Division of Ontario, Canada. Medical Genetics, UCSF, San Francisco, CA.
89B 96C The fourth function of the cell wall. Hiroki Okada, Characterization of double budding in wild-type Shinsuke Ohnuki, Yoshikazu Ohya. Integrated Biosciences, Saccharomyces cerevisiae. Angela L. Piotrowski, Robert University of Tokyo, Kashiwa, Chiba, Japan. M. Seiser. Roosevelt University, Schaumburg, IL.
90C 97A Roles of four putative Cyk3-binding proteins in Ubiquitylation may promote the Glc7 activity opposing Ipl1 kinase during mitosis. R. Ravindran1, P. Polk2, L. coordination of cleavage-furrow ingression and 1 1 abscission during cytokinesis. Masayuki Onishi, Meng C. Robinson , K. Tatchell . 1) Biochemistry and Molecular Wang, John Pringle. Dept Gen, Stanford Univ, Stanford, Biology, LSUHSC, Shreveport, LA; 2) Research Core CA. Facility, LSUHSC, Shreveport, LA.
91A 98B Contribution of metabolic adaptation and chronological The efflux pump MlcE from the Penicillium solitum aging to cell differentiation within yeast colonies. Zdena compactin biosynthetic gene cluster increases Palkova1, Libuse Vachova2, Michal Cap1, Marcela Saccharomyces cerevisiae resistance to natural statins. Hejlova2. 1) Department of Genetics and Microbiology, Ana Rems, Rasmus John Normand Frandsen. DTU Charles University in Prague, 128 44 Prague 2, Czech Systems Biology, Technical University of Denmark, Republic, [email protected]; 2) Institute of Kongens Lyngby, Denmark. Microbiology of the ASCR, v.v.i., 142 20 Prague 4, Czech Republic.
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Poster Session Listings
99C Dasika, Lan Xu, Lily Chao, Savita Ganesan, Jefferson Lai, Determining the adaptive landscape of the SUL1 Patrick Westfall, Timothy Gardner, Annie Tsong. Amyris promoter. Matthew S. Rich1, Celia Payen1, Maitreya J. Inc., Emeryville, CA. Dunham1, Stanley Fields1,2,3. 1) Department of Genome Sciences, University of Washington, Seattle, WA; 2) 107B Department of Medicine, University of Washington, An “oncometabolite” in yeast: 2-hydroxyglutarate Seattle, WA; 3) Howard Hughes Medical Institute, accumulates in response to altered mitochondrial and University of Washington, Seattle, WA. central carbon metabolism. Olga Zaslaver1,2, Adam Rosebrock1, Amy Caudy1,2. 1) Donnelly Centre for Cellular 100A and Biomolecular Research, University of Toronto, Physiological role of nitric oxide as a signaling molecule Toronto, ON, Canada; 2) Department of Molecular in the regulation of sporulation in Saccharomyces Genetics, University of Toronto, Toronto, ON, Canada. cerevisiae. Kyohei Saiki, Akira Nishimura, Iwao Ohtsu, Daisuke Watanabe, Hiroshi Takagi. NAIST, Nara, Japan.
101B Cell Biology: Cytoskeleton New insights into glucose sensing by S. cerevisiae. Kobi Simpson-Lavy, Mark Johnston. Biochemistry and Molecular Genetics, CU-Denver School of Medicine, Aurora, CO, 80045. 108C Linker scanning mutagenesis of microtubule nucleating 1 102C components Spc97 and Spc98. Kimberly Fong , Jerry 1 2 1 1 A minimal glycolytic pathway in Saccharomyces Tien , Celia Payen , Alex Zelter , Beth Graczyk , Maitreya cerevisiae. D. Solis-Escalante1, N. Barrajón Simancas1, N. Dunham2, Trisha Davis1. 1) Department of Biochemistry, G. Kuijpers1, J. T. Pronk1,2, JM. Daran1,2, P. Daran- University of Washington, Seattle, WA; 2) Department of Lapujade1. 1) Department of Biotechnology, Delft Genome Sciences, University of Washington, Seattle, WA. University of Technology, Delft, The Netherlands; 2) Platform Green Synthetic Biology, Delft, The Netherlands. 109A Regulation of the kinetochore localization and activity 1,2 103A of the protein kinase Mps1 during mitosis. Lori Koch , 2 Improvement of ethanol stress tolerance in an industrial Sue Biggins . 1) Molecular and Cellular Biology, fuel-ethanol Saccharomyces cerevisiae strain. A. Bucker, University of Washington, Seattle, WA; 2) Basic Sciences, J. C. do Espirito-Santo, G. Muller, M. G. Dario, B. U. Fred Hutchinson Cancer Research Center, Seattle, WA. Stambuk. Dept Biochemistry, Univ Federal de Santa Catarina, Florianopolis, Santa Catarina, Brazil. 110B Kinetochores require oligomerization of the Dam1 104B complex to maintain microtubule attachments against 1 Feral strains forming biofilm colonies are derived from tension during biorientation. Neil Umbreit , Matthew 2 1 1 domesticated strains under stress conditions. Libuse Miller , Jérôme Cattin-Ortolá , Jerry Tien , Charles Vachova1, Zdena Palkova2, Vratislav Stovicek2, Marketa Asbury3, Trisha Davis1. 1) Department of Biochemistry, Begany1. 1) Institute of Microbiology of the ASCR, v.v.i., University of Washington, Seattle, WA; 2) Division of 142 20 Prague 4, Czech Republic, Basic Sciences, Fred Hutchinson Cancer Research Center, [email protected]; 2) Department of Genetics and Seattle, WA; 3) Department of Physiology and Biophysics, Microbiology, Charles University in Prague, 128 44 Prague University of Washington, WA. 2, Czech Republic. 111C 105C Quality Control of Higher-order Septin Assembly: Identification of yeast Greatwall kinase Rim15p as a Mapping the Septin Proteostasis Network in vivo. novel negative regulator for alcoholic fermentation. Andrew Weems, Michael McMurray. Cell and Daisuke Watanabe1,2, Yan Zhou2, Aiko Hirata3, Developmental Biology, University of Colorado Anschutz Yoshikazu Ohya3, Takeshi Akao2, Hitoshi Shimoi2, Hiroshi Medical Campus, Aurora, CO. Takagi1. 1) NAIST, Nara, Japan; 2) NRIB, Hiroshima, Japan; 3) University of Tokyo, Kashiwa, Japan. 112A Crosslinking analysis identifies hundreds of distance 1 106A constraints in protein complexes. Alex Zelter , Michael 2 3 3 Re-inventing central carbon metabolism in Hoopman , Richard Johnson , Michael MacCoss , Robert 2 1 Saccharomyces cerevisiae for high-volume production of Moritz , Trisha Davis . 1) Department of Biochemistry farnesene. Kati Wu, Kristy Hawkins, Yoseph Tsegaye, University of Washington, Seattle, WA; 2) Institute for Adam Meadows, Lauren Pickens, Anna Tai, Tina Systems Biology, Seattle, WA; 3) Department of Genome Mahatdejkul-Meadows, Eugene Antipov, Madhukar Sciences, University of Washington, Seattle, WA.
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Poster Session Listings
121A Multiple MAPK cascades regulate the transcription of Cell Biology: IME1, the master transcriptional activator of meiosis in Mating/Sporulation/Meiosis Saccharomyces cerevisiae. Yona Kassir1, Smadar Kahana-Edwin2, Michal Stark1. 1) Dept Biol, Technion Inst, Haifa, Israel; 2) Cancer Research Center, Sheba Medical Center, Tel-Hashomer, Israel 52621.
113B 122B Regulation of the Ndc80 complex during meiosis in 1 2 Schizosaccharomyces japonicus provides the second budding yeast. Jingxun Chen , Angelika Amon , Elcin 1 example where chirality of DNA strands causes sister- Unal . 1) Department of Molecular and Cell Biology, sister cells developmental asymmetry. Amar J. S. Klar. University of California, Berkeley, Berkeley, CA; 2) Gene Reg & Chromosome Biol Lab, NCI-Frederick Cancer Department of Biology, Massachusetts Institute of Res Fac, Frederick, MD. Technology, Cambridge, MA.
123C 114C A mating pathway deficiency as a reproductive barrier To What Extent Does Homologous Chromosome between Saccharomyces cerevisiae and Saccharomyces Pairing Depend on Recombination-Independent paradoxus. Camille Meslin1, Allyson O'Donnell2, Nathan Chromosome Interactions? S. Cheng, A. MacQueen. Clark1. 1) Computational and Systems Biology, University Wesleyan University, Middletown, CT. of Pittsburgh, Pittsburgh, PA; 2) Cell Biology, University of Pittsburgh, PA. 115A Regulation of nuclear shape in response to mating 124A pheromone. Alison Walters, Emma Dauster, Orna Cohen- Fix. NIDDK/NIH, LCMB, Bethesda, MD. A developmental stage-specific Vps13 complex regulates phsophatidylinositol-4-phosphate pools. Jae-Sook Park, Aaron Neiman. Biochem & Cell Biol, SUNY Stony Brook, 116B Stony Brook, NY. Developmentally-programmed mega-autophagy drives mother cell demise during yeast gametogenesis. Michael 125B Eastwood, Marc Meneghini. Moleular Genetics, University of Toronto, Toronto, Ontario, Canada. SPS1 and SPO77 act together to regulate prospore membrane closure during sporulation in S. cerevisiae. Scott Paulissen, Christian Slubowski, Linda Huang. 117C Biology, University of Massachusetts Boston, Boston, MA. Role of CWI-pathway and Rlm1 transcription factor in colony sporulation patterns. Sarah Piccirillo, Rita 126C Morales, Melissa G. White, Keston Smith, Saul M. Characterizing the function of Kar5p during inner Honigberg. Cell Biol/Biophysics, School Biol Sciences, Univ Missouri-Kansas City, Kansas City, MO. nuclear membrane fusion during yeast mating. Jason V. Rogers, Mark D. Rose. Department of Molecular Biology, Princeton University, Princeton, NJ. 118A Mating and mating-type determination in the yeast 127A Kluyveromyces marxianus. H. Hoshida, S. Murashige, S. Quantification of Meiotic Chromosome Missegregation Tokuda, R. Akada. Dept Appl Mol Biosci, Yamaguchi Univ, Ube, Yamaguchi, Japan. Frequency in Natural Isolates of Saccharomyces cerevisiae. Amy Carol Sirr, Gareth Cromie, Aimée Dudley. Pacific Northwest Diabetes Research Inst, Seattle, 119B WA. dHJ-C, a Tool for Genome-Wide Mapping of Homologous Recombination and Template Choice 128B During Yeast Meiosis. Neil A. Humphryes, Tovah Kel1p collaborates with Fus2p for yeast cell fusion. Jean Markowitz, Xiaoji Sun, Viji Subramanian, Andreas Smith, Richard Stein, Mark Rose. Molecular Biology, Hochwagen. Biology, NYU, NYC, NY. Princeton University, Princeton, NJ.
120C 129C Translational regulation determines gene insulation KAR4 has separable functions in mating and multiple during yeast meiosis. Liang Jin, Rolf Sternglanz, Aaron steps of meiosis. Abigail J. Sporer, Mark D. Rose. Neiman. Department of Biochemistry and Cell Biology, Molecular Biology, Princeton University, Princeton, NJ. Stony Brook University, Stony Brook, NY.
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Poster Session Listings
130A 136A Unprogrammed presentation number Aconitase-MRPL49 fusion protein regulates mitochondrial translation in S. pombe. Soo-Jin Jung, 131B Youngdae Seo, Jung-Hye Roe. Seoul National University, Investigating the roles of alternate and short ORFs in Seoul, South Korea. meiosis. Kelsey Van Dalfsen, Gloria Brar. Molecular and Cell Biology, UC-Berkeley, Berkeley, CA. 137B MTG3, a putative GTPase that regulates mitochondrial ribosome function in Saccharomyces cerevisiae . Upasana Mehra, Yash Verma, Kaustuv Datta. Department Cell Biology: of Genetics, University of Delhi, New Delhi, India.
Mitochrondria/Vacuoles/Peroxisomes 138C A genetic screen for suppressors of the age-associated decline of mitochondrial membrane potential. NH Thayer1,2, MA Borden1, AL Hughes1,3, D. Lindstrom1, FS 4 4 1 132C Vizeacoumar , C. Boone , DE Gottschling . 1) Fred Mitochondrial ribosome function/assembly: Regulation Hutchinson Cancer Research Center, Seattle, WA; 2) by accessory factors in Saccharomyces cerevisiae. Molecular and Cellular Biology Program, University of Kaustuv Datta, Jaswinder Kaur, Dharmendra Pandey. Washington, Seattle, WA; 3) Current Location: Biological Department of Genetics , University of Delhi South Chemistry, University of Utah, Salt Lake City, UT; 4) Campus, New Delhi, India. University of Toronto, Toronto, ON.
133A 139A PEP3 overexpression protects yeast from acid stress by A sterol-enriched vacuolar microdomain mediates the promoting vacuolar biogenesis. J. Ding1,2, G. Holzwarth2, stationary phase lipophagy in budding yeast. Yu-Hsuan S. Bradford3, B. Cooley4, A. Yoshinaga5, J. Patton-Vogt4, Miao, Yi-Shun Chang, Chao-Wen Wang. Inst Plant & H. Abeliovich6, M. Penner2, A. Bakalinsky1,2. 1) Microbial Biol, Academia Sinica, Taipei, Taiwan. Department of Biochemistry & Biophysics, Oregon State University, Corvallis, OR, USA; 2) Department of Food 140B Science & Technology, Oregon State University, Corvallis, Membrane insertion mechanisms of mitochondrially- OR, USA; 3) Environmental & Molecular Toxicology, encoded proteins by the Oxa1 homolog, Cox18. Mei-Yi Oregon State University, Corvallis, OR, USA; 4) Zheng, Heather L. Fiumera. Dept. of Biological Sciences, Biological Sciences, Duquesne University, Pittsburgh, PA, Binghamton University, Binghamton, NY. USA; 5) Department of Microbiology, Oregon State University, Corvallis, OR, USA; 6) Department of
Biochemistry and Food Science, Hebrew University, Rehovot, Israel. Cell Biology: Protein Sorting and Turnover 134B Ysp1 homologous proteins participate in responses to membrane stress in S. cerevisiae and S. pombe. Vladimir Sirotkin1, Michael James1, Elizabeth Bonarigo2, Gary Franke2, Kelly Hopkins2, Scott Erdman1,2. 1) Dept of Cell 141C and Developmental Biology, SUNY Upstate School of Specific α-arrestins negatively regulate Saccharomyces Medicine, Syracuse, NY; 2) Dept Biol, Syracuse Univ, cerevisiae pheromone response by down-modulating the Syracuse, NY. G-protein coupled receptor Ste2. Christopher Alvaro1, Allyson O'Donnell2, Ann Aindow1, Derek Prosser3, Andrew Augustine2, Aaron Goldman4, Jeff Brodsky2, 135C Martha Cyert4, Beverly Wendland3, Jeremy Thorner1. 1) Elucidation of the Mitochondrial Protein-Protein 1 Div. of Biochemistry, Biophysics and Structural Biology, Interaction Network. Matthew G. M. Jessulat , Hiroyuki 1 1 2 1,3 Dept. of Molecular and Cell Biology, Univ. of California, Aoki , Zoran Minic , James Vlasblom , Sadhna Phanse , 3 4 1 Berkeley, CA; 2) Dept. of Cell Biology, Sch. of Med., Zhaolei Zhang , Jodi Nunnari , Mohan Babu . 1) Univ. of Pittsburgh, Pittsburgh, PA; 3) Dept. of Biology, Department of Chemistry and Biochemistry, University of Johns Hopkins Univ., Baltimore, MD; 4) Dept. of Biology, Regina, Regina, Saskatchewan, Canada; 2) Department of Stanford Univ., Stanford, CA. Chemistry, University of Toronto, Toronto, Canada; 3) Banting and Best Department of Medical Research, Donnelly Center, University of Toronto, Toronto, Ontario, Canada; 4) Department of Microbiology and Molecular Genetics, University of California Davis, California, USA.
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Poster Session Listings
142A 149B Stress conditions promote Gap1 permease Vps13 plays a role at the early and late endosomes. ubiquitylation and downregulation via the arrestin-like Kathleen L. Kolehmainen1,2, Elizabeth Conibear2. 1) Bul and Aly proteins. M. Crapeau, A. Merhi, B. Andre. Biochemistry and Molecular Biology, University of British IBMM, Free University of Brussels, Gosselies, Belgium. Columbia, Vancouver, British Columbia, Canada; 2) Centre for Molecular Medicine and Therapeutics, 143B Vancouver, British Columbia, Canada. The protein quality control machinery regulates its misassembled proteasome subunits, and distinguishes 150C them from proteasome storage granules. S. Ben-Aroya, Dissecting natural variation in yeast to identify genetic L. Peters, O. Yogev, R. Hazan. Bar-Ilan University, Ramat- modifiers of protein aggregation. Theodore W. Peters, Gan, Israel. Christopher S. Nelson, Akos A. Grencser, Kathleen J. Dumas, Gordon J. Lithgow, Rachel B. Brem, Robert E. 144C Hughes. Buck Institute for Research on Aging Novato, CA. Cdc48-Shp1 chaperone promotes structural integrity of protein phosphatase 1 holoenzyme. You-Liang Cheng1,2, 151A Rey-Huei Chen1. 1) Institute of Molecular Biology, Impairment of translocon-associated protein Academia Sinica, Taipei, Taiwan; 2) Graduate Institute of degradation under conditions of endoplasmic reticulum Life Sciences, National Defense Medical Center, Taipei, stress. Eric M. Rubenstein1, Mark Hochstrasser2. 1) Taiwan. Department of Biology, Ball State University, Muncie, IN; 2) Department of Molecular Biophysics and Biochemistry, 145A Yale University, New Haven, CT. The Yeast Biogenesis of Lysosome Related Organelle (BLOC) Complex interacts with ESCRT to regulate 152B endosomal trafficking. Lauren E. Dalton1, Matthew Substrate-induced ubiquitylation and endocytosis of Jessulat2, Viktor Deineko2, Jeffery Tong1, Mohan Babu2, Gap1 and Can1 permeases: role of arrestin-like Elizabeth Conibear1. 1) Biochemistry and Molecular proteins. Elie Saliba1, Kassem Ghaddar1, Ahmad Merhi1, Biology, University of British Columbia, Vancouver, BC, Eva-Maria Krammer2, Martine Prévost2, Bruno André1. 1) Canada; 2) Department of Biochemistry, Research and Molecular Physiology of the Cell, Université Libre de Innovation Centre, University of Regina, Regina, Bruxelles, IBMM, 6041 Gosselies, Belgium; 2) Structure Saskatchewan, Canada. and Function of Biological Membranes, Université Libre de Bruxelles, Campus Plaine, 1050 Brussels, Belgium. 146B Identifying new protein trafficking networks using 153C evolutionary rate covariation (ERC). Zelia A. Ferreira1, Mitochondrial dynamics and the selectivity of Allyson F. O'Donnell2, Nathan L. Clark1. 1) Computational mitophagic processes. Kobi J. Simpson-Lavy, Hagai and Systems Biology, University of Pittsburgh, 15260, Abeliovich. Department of Biochemistry and Food Science, Pittsburgh, PA; 2) Dept. of Cell Biology, Univ. of Hebrew University of Jerusalem, Rehovot, Israel. Pittsburgh, 15260, Pittsburgh, PA. 154A 147C A direct role of HRD3 in ER associated degradation Hsp31 is a Stress-response Chaperone that Prevents α- (ERAD). Nidhi Vashistha1, Sarah Carroll2, Randolph Synuclein Aggregation. Chai-jui Tsai1, Kiran Aslam1, Hampton1. 1) Cell and Developmental Biology, University Holli Drendel2, Josephat Asiago1, Kourtney Fultz1, Jean- of California San Diego, La Jolla, CA; 2) University of Christophe Rochet1, Tony Hazbun1. 1) Department of Washington, Seattle,WA. Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN; 2) Department of Medical 155B and Molecular Genetics, Indiana University School of The alternate clathrin adaptor complex subunit Apm2 Medicine, Indianapolis, IN. works with Ima1p in a distinct protein transport pathway. Shawn T. Whitfield1,2, Helen E. Burston2, 148A Nandini Raghuram2, Elizabeth Conibear2. 1) Biochemistry Degeneracy of parameters underlying partitioning of and Molecular Biology, University of British Columbia, macromolecular content upon yeast cell division. Ali Vancouver, British Columbia, Canada; 2) Centre for Kinkhabwala2, Anton Khmelinskii1, Michael Knop1. 1) Molecular Medicine and Therapeutics, Vancouver, British ZMBH, University of Heidelberg, Heidelberg, Germany; 2) Columbia, Canada. Max Planck Institut of molecular Physiology, Dortmund, Germany.
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Poster Session Listings
162C Cell Biology: Signal Transduction Med13p anchors cyclin C in the nucleus to prevent stress-independent mitochondrial fragmentation and stress hypersensitivity. Katrina F. Cooper, Svetlana Khakhina, Chunyan Jin. Dept Molec Biol, Rowan 156C University-SOM, Stratford, NJ. Non-Preferred Carbon Source Utilization Induces Snf1p- and ER Stress-Dependent Activation of the High 163A Osmolarity Glycerol (HOG) Pathway. Hema Adhikari, Tor1 and PKA downregulation in stationary phase rely Paul Cullen. Department of Biological Sciences at SUNY- on Mtl1 to preserve mitochondrial integrity and cell Buffalo, NY 14260-1300. survival. Venkatraghavan Sundaran1, Mima Petkova1, Nuria Pujol-Carrion1, Jordi Boada2, Maria Angeles de la 1 157A Torre-Ruiz . 1) Basic Medical Sciences-IRBLleida, ER Stress Stimulates Mucin Receptor Signaling From University of Lleida, LLEIDA, Spain; 2) Experimental the Secretory Pathway. Hema Adhikari1, Nadia Vadaie1, Biology-IRBLleida, University of Lleida, Lleida, Spain. Jacky Chow1, Christopher Stefan2, Jason MacGurn2, Paul 1 Cullen . 1) Department of Biological Sciences at SUNY- 164B Buffalo, 14260-1300; 2) Weill Institute for Cell and Calcineurin regulates the yeast synaptojanin Inp53/Sjl3 Molecular Biology & Department of Molecular Biology during membrane stress. Evan Guiney1, Joshua Elias2, and Genetics Cornell University Ithaca NY 14853-7202. Martha Cyert1. 1) Biology, Stanford University, Stanford, CA; 2) Chemical and Systems Biology, Stanford 158B University, Stanford, CA. Quantifying the effect of coding sequence variation in human orthologs of Saccharomyces cerevisiae Bim1 on 165C 1,2,3 1 the pheromone response. D. Britain , B. Sands , W. TOR Complex 1 is a direct target of amino acid sensor Peria1, G. Pesce4, R. Brent1,2,5. 1) Division of Basic Gcn2. Wenjie Yuan, Yu Jiang. Department of Sciences, Fred Hutchinson Cancer Research Center, Pharmacology and Chemical Biology, Univ Pittsburgh, Seattle, WA; 2) Department of Bioengineering, University Pittsburgh, PA. of Washington, Seattle, WA; 3) Department of Biochemistry, University of Washington, Seattle, WA; 4) 166A The Molecular Sciences Institute, Berkeley, CA; 5) Protein-Protein Interactions of the Yak1 Kinase. Department of Genome Sciences, University of Adeline Boettcher, Scott Blaszak, Samantha J. DeWerff, Washington, Seattle, WA. Stephen D. Johnston. Department of Biology, North Central College, Naperville, IL. 159C Global Analysis of Filamentous Growth Pathway 167B Regulators in Yeast. Colin A. Chavel, Lauren M. Endolysosomal membrane trafficking complexes drive Caccamise, Boyang Li, Paul J. Cullen. University at nutrient-dependent TORC1 signaling to control cell Buffalo, SUNY, Buffalo, NY. growth in Saccharomyces cerevisiae. Joanne M. Kingsbury, Neelam D. Sen, Maria E. Cardenas. 160A Department of Molecular Genetics and Microbiology, Structure and function of the TORC1-PKA signaling Duke University Medical Center, Durham, NC. network in budding yeast. James Hughes Hallett, Joe Kunkel, Xiangxia Luo, Andrew Capaldi. University of 168C Arizona, Tucson, AZ. Membrane fluidity and temperature sensing are coupled via circuitry comprised of Ole1, Rps5, and Hsf1 161B in Candida albicans. Michelle Leach1,2, Leah Cowen1. 1) The Cdc42-Interacting Protein Bem4 Regulates the Department of Molecular Genetics, University of Toronto, Filamentous Growth Pathway. Colin A. Chavel1, Toronto, Ontario, Canada; 2) Aberdeen Fungal Group, Andrew Pitoniak1, Jeremy Smith1, Diawoye Camera1, University of Aberdeen, Institute of Medical Sciences, Jacky Chow1, Sheelarani Karunanithi1, Ken Wolfe2, Paul Aberdeen, UK. Cullen1. 1) University at Buffalo, SUNY, 337 Cooke Hall, North Campus, Buffalo, NY 14260; 2) Smurfit Institute of 169A Genetics,Trinity College, University of Dublin, Dublin 2, Regulation of the essential protein kinase Ypk1 by the Ireland. TORC2 complex. Kristin Leskoske, Françoise Roelants, Jeremy Thorner. Div. of Biochemistry, Biophysics and Structural Biology, Dept. of Molecular and Cell Biology, Univ. of California, Berkeley, CA 94720-3202 USA.
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Poster Session Listings
170B 177C Latency of transcription factor Stp1 depends on a Functional characterization of protein interactors of modular regulatory motif that functions as cytoplasmic Wsc1p and Mid2p stress sensors and PKC1 signaling in retention determinant and nuclear degron. Deike J. Saccharomyces cerevisiae. Ednalise Santiago- Omnus, Per O. Ljungdahl. Dept Molecular Biosciences, Cartagena1, Vladimir Vélez-Segarra1, Igor Stagljar2, Brian Wenner-Gren Inst, Stockholm Univ, Stockholm, Sweden. C. Rymond3, José R. Rodriguez-Medina1. 1) Biochemistry, University of Puerto Rico- Medical Sciences Campus, San 171C Juan, PR; 2) Donnelly Centre for Cellular and The phosphorylation state of Saccharomyces cerevisiae Biomolecular Research, University of Toronto, Canada; 3) signaling proteins varies in a stress-dependent fashion. University of Kentucky, Lexington, KY. Matthew MacGilvray1, Anna Larson2, David Berry3, Josh Coon2, Audrey Gasch1. 1) Laboratory of Genetics, 178A University of Wisconsin-Madison, Madison , WI; 2) Plasma membrane flippase function is required for Department of Chemistry, University of Wisconsin- signaling competence in the mating pheromone Madison, Madison, WI; 3) Institute for Neurodegenerative response pathway. Elodie A. Sartorel, Evelyne Barrey, Disease, UCSF School of Medicine, San Francisco, CA. Rebecca Lau, Jeremy Thorner. Molecular and cell biology, University California Berkeley, Berkeley, CA. 172A Substrate sequence specificity and catalytic properties 179B of the signaling Ssy5 endoprotease. Antonio Martins, Role of the Glc7-Reg1/2 phosphatase in the control of Per Ljungdahl. Department of Molecular Biosciences, The the Mig1 transcriptional repressor. Sviatlana Wenner-Gren Institute, Stockholm University, Stockholm, Shashkova1, Raul Garcia-Salcedo1, Loubna Bendrioua1, Sweden. Timo Lubitz2, Niek Welkenhuysen1, Edda Klipp2, Stefan Hohmann1. 1) Chemistry and Molecular Biology, 173B University of Gothenburg, Sweden; 2) Theoretical TORC1 regulates the yeast lipin Pah1 via the Biophysics, Humboldt-Universität zu Berlin, Germany. Nem1/Spo7 protein phosphatase complex. Emmanuelle Dubots, Stéphanie Cottier, Marie-Pierre Péli-Gulli, Malika 180C Jaquenoud, Séverine Bontron, Marta Moreno Torres, Components of the Vid30 complex participates in the Roger Schneiter, Claudio De Virgilio. Department of transcriptional regulation of glucose-repressed genes in Biology, Unit of Biochemistry, University of Fribourg, Saccharomyces cerevisiae. Angus Ross, Chris Snowdon, Fribourg, Switzerland. Andrew Fletcher, George van der Merwe. Department of Molecular & Cellular Biology, University of Guelph, 174C Guelph, Canada. TORC2-dependent Protein Kinase Ypk1 Phosphorylates Ceramide Synthase Components Lag1 181A and Lac1 to Stimulate Sphingolipid Synthesis. Dynamics of MAPK signaling in Saccharomyces Alexander Muir, Subramaniam Ramachandran, Françoise cerevisiae. Sarah Weisser1,3, Konstanze Bandmann2,3, Roelants, Garrett Timmons, Jeremy Thorner. Department Julia van der Felden1,3, Peter Lenz2,3, Hans-Ulrich of Molecular and Cell Biology, University of California, Mösch1,3. 1) Department of Genetics, Philipps-Universität Berkeley, Berkeley, CA. Marburg, Karl-von-Frisch-Straβe 8, 35043 Marburg, Germany; 2) Department of Physics, Philipps-Universität 175A Marburg, Renthof 6, 35032 Marburg, Germany; 3) Target of rapamycin-responsiveness on the GATA- LOEWE-Center for Synthetic Microbiology family transcription activator Gln3. Rajendra Rai1, (SYNMIKRO), Hans-Meerwein-Straβe, 35043 Marburg. Jennifer J. Tate1, Karthik Shanmuganatham2, Martha M. Howe1, Terrance G. Cooper1. 1) Dept. Microbiol., 182B Immunol. and Biochem., Univ. Tennessee, Memphis, TN; Glucose derepression via Snf1-Mig1 is controlled at 2) Dept. Infectious Disease, St. Jude Children's Research different levels. Niek Welkenhuysen, Tian Ye, Raul Hospital, Memphis, TN. Garcia-Salcedo, Stefan Hohmann. Department of Chemistry and Molecular Biology, University of 176B Gothenburg, Gothenburg, Sweden. Endocytosis and vacuolar degradation of the yeast cell surface glucose sensors Rgt2 and Snf3. A. Roy, J. H. 183C Kim. Biochemistry and Molecular Medicine, The George Dissecting the role of calcineurin and protein kinase C Washington University, Washington , DC. signalling in Hsp90-dependent caspofungin tolerance. Jinglin L. Xie1, Michelle D. Leach1,2, Leah E. Cowen1. 1) Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; 2) Aberdeen Fungal Group, School of Medical Sciences, Institute of Medical Sciences,
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Poster Session Listings
University of Aberdeen, Foresterhill, Abderdeen, United 190A Kingdom. The osmotolerant yeast Zygosaccharomyces rouxii possesses two differently regulated glycerol transporters. Michala Bubnová1, Hana Sychrová1, 184A 2 TORC1 and TORC2 regulate Rps6 phosphorylation via Candida Lucas . 1) Department of Membrane Transport, Ypk1/2/3 in budding yeast. Seda Yerlikaya1, Madeleine Institute of Physiology Academy of Sciences of the Czech Meusburger1, Alexandre Huber1, Dorothea Anrather2, Republic, v.v.i, Prague, Czech Republic; 2) Departement of Gustav Ammerer2, Robbie Loewith1,3. 1) Molecular Biology, University of Minho, Campus de Gualtar, Braga, Biology, University of Geneva, Geneva, Switzerland; 2) Portugal. Max F. Perutz Laboratories, Department of Biochemistry, University of Vienna, Dr. Bohrgasse 9, A1030 Vienna, 191B Austria; 3) Swiss National Centre for Competence in A conserved role for GSK3β in regulating lipid Research Programme Chemical Biology, Geneva 1211, homeostasis through lipins. Leslie J. Chan1,5, Jennifer Switzerland. McQueen1,3,5, Timothy R. Peterson2,5, Meredith Briggs1, David M. Sabatini2,4, Vivien Measday3, Christopher J. R. 1 185B Loewen . 1) Department of Cellular and Physiological Mechanisms of nitrogen in regulating cAMP signal in Sciences, University of British Columbia, Vancouver, Saccharomyces cerevisiae. Y. Li1, A. Zhang1,2, H. Jin1. 1) British Columbia, V6T 1Z3, Canada; 2) Whitehead Hebei University of Technology, No8 Guangrong Institute for Biomedical Research, Cambridge, MA 02142, Road,Hongqiao District, Tianjin,China; 2) Tianjin USA; 3) Wine Research Centre, Faculty of Land and Food University, No92 Weijin Road, Nankai District, Tianjin, Systems, University of British Columbia, Vancouver, China. British Columbia, V6T 1Z3, Canada; 4) Howard Hughes Medical Institute; 5) These authors contributed equally to this work. 186C Characterization of the Recruitment of Casein Kinase 1 to P Bodies. Bo Zhang, Khyati Shah, Qian Shi, Paul 192C Herman. Molecular Genetics, The Ohio State University, Characterization of Candida glabrata growth and cell Columbus, OH 43210. wall enzymes in during stress. Yuanyuan Chew, Cheen Fei Chin, Foong May Yeong. Biochemistry, National University of Singapore, Singapore, Singapore.
Cell Biology: Other 193A The JmjC Domain-containing Regulator Gis1 is Regulated by Levels of Heme and Oxygen
Independently. Jonathan M. Comer, Ajit Shah, Sneha Lal, Thai Cao, Jagmohan Hooda, Li Zhang. Molecular and 187A Cell Biology, University of Texas at Dallas, Richardson, An overexpression suppressor screen to identify genes TX. that are effectors of nuclear morphology in Saccharomyces cerevisiae. James T. Arnone, Orna Cohen-Fix. Laboratory of Cell and Molecular Biology, 194B NIDDK/NIH, Bethesda, MD. Characterization of the CIA complex in maintaining genome stability. Lilach Emuna, Marina Volpe, Galit David Kadoch, Shay Ben A. roya. Faculty of Life Science, 188B Bar-Ilan University, Ramat-Gan, Israel. A cell biological screen for age dependent changes in lipid metabolic pathways reveals changes in sphingolipid pathways. Anthony O. Beas, Karen L. Zhao, 195C Daniel E. Gottschling. Division of Basic Sciences, Fred [PSI+], a prion-containing yeast cell, can switch into Hutchinson Cancer Research Center, Seattle, WA. agar-invasive growth while [psi-] ,a non-prion strain cannot. Irene M. Evans, Ying Peng Lee, Prashanti Patil, Haeja A. Kessler, Dylan S. Weil, Brandy A. Dennis. Irene 189C M. Evans, Rochester Inst Tech, Rochester, NY 14623. Molecular switches of Golgi size control. Madhura D. Bhave, Prasanna Iyer, Bhawik Jain, Dibyendu Bhattacharyya. Bhattacharyya lab, Advanced Centre for 196A Treatment, Research & Education in Cancer (ACTREC), The Role of Phosphorylation in Ribosomal Protein L4. Tata Memorial Centre, Kharghar, Sector 22, Navi Mumbai- Jesse Michael Fox, Lasse Lindahl. Biological Sciences, 410 210. MH INDIA. University of Maryland, Baltimore County, Baltimore, MD.
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Poster Session Listings
197B 205A Understanding the role of the translation factor eIF5A Swi3, a novel regulator of aerobic respiration genes and through genetic interaction network of different oxygen metabolism in Saccharomyces cerevisiae. Sneha mutants. Fabio C. Galvao1, Sara Sharifpoor2, Danuza Lal, Jagmohan Hooda, Md Maksudal Alam, Ajit Shah, Rossi1, PPaulo E. G. Boldrin1, Natalia M. Barboas1, Brenda Thai Cao, Li Zhang. Molecular and Cell Biology, J. Andrews2, Cleslei F. Zanelli1, Sandro R. Valentini1. 1) University of Texas at Dallas, Richardson, TX. Biological Science, UNESP-Univ. Estadual Paulista, Araraquara, São Paulo, Brazil; 2) Department of Molecular 206B Genetics, The Donnelly Centre for Cellular and Mechanism of Non-Genetic Heterogeneity in Growth Biomolecular Research, University of Toronto. Rate of Saccharomyces cerevisiae. Shuang Li, Mark Siegal. Department of Biology, New York University, New 198C York, NY. Allele-specific SGA screening to identify functions for ER polarization. Analise K. Hofmann, Andrew K. O. 207C Wong, Christopher J. R. Loewen. 2350 Health Sciences Heavy Water Promotes Longevity in Yeast. Xiyan Li, Mall University of British Columbia Vancouver, B. C. Michael Snyder. Genetics, Stanford University, Stanford, Canada V6T 1Z3. CA.
199A 208A YlSnf1 Affects the Production of Omega-3 Fatty Acids Characterizing SUMO Function in Saccharomyces from Yarrowia lipolytica. J. Seip, R. Jackson, H. He, Q. cerevisiae Using a Versatile Library of Synthetic SMT3 Zhu, S.-P. Hong. Biotechnology, DuPont Central R&D, Mutants. P. B. Meluh1, H. A. Newman2, J. Lu2, J. D. Wilmington, DE. Boeke3, M. J. Matunis2. 1) Dept Mol Biol & Gen, Johns Hopkins Univ Sch Med, Baltimore, MD; 2) Dept. Biochem 200B & Mol Biol, Johns Hopkins Bloomberg Sch Public Health, PM - ER Membrane Tethering Complexes and Non- Baltimore, MD; 3) Dept Biochem & Mol Pharm, NYU vesicular Sterol Transport. Jesper Johansen1, Evan Langone Univ Sch of Med, New York, NY. Quon1, Yves Sere2, Anant K. Menon2, Christopher T. Beh1. 1) Molecular Biology and Biochemistry, Simon Fraser 209B University, Burnaby, British Colombia, Canada; 2) Changes in transcription and metabolism during the Department of Biochemistry, Weill Cornell Medical early stage of replicative cellular senescence in budding College, New York, NY. yeast. Yukio Mukai1, Yuka Kamei1, Yoshihiro Tamada2, Yasumune Nakayama2, Eiichiro Fukusaki2. 1) Department 201C of Bioscience, Nagahama Institute of Bio-Science and Hsp104 as stress indicator in hybrids of the Technology, 1266 Tamura-cho, Nagahama, Shiga 526- Saccharomyces sensu stricto complex. Claudia Kempf, 0829, Japan; 2) Department of Biotechnology, Graduate Jürgen Wendland. Carlsberg Laboratory, Copenhagen, School of Engineering, Osaka University, 2-1 Yamadaoka, Denmark. Suita, Osaka 565-0871, Japan.
202A 210C Roles of the Yap1 Transcription Factor and Changes in intracellular abundance and localization of Antioxidants in Saccharomyces cerevisiae’s Tolerance to Saccharomyces cerevisiae Hsp31p under various Furfural and 5-Hydroxymethylfurfural, which Function environmental stresses suggest its role in neutralizing as Thiol-Reactive Electrophiles Generating Oxidative the effects of oxidative stress insult. Urszula Stress. Daehee Kim, Ji-Sook Hahn. Chemical and Natkanska1, Adrianna Skoneczna2, Marek Skoneczny1. 1) Biological engineering, Seoul National University, Seoul, Department of Genetics, Institute of Biochemistry and South Korea. Biophysics Polish Academy of Sciences, Warszawa, Poland; 2) Laboratory of Mutagenesis and DNA Repair, 203B Institute of Biochemistry and Biophysics Polish Academy A metabolic strategy to enhance long-term survival by of Sciences, Warszawa, Poland. Phx1 through stationary phase-specific pyruvate decarboxylases in fission yeast. Eun Jung Kim, Ji Yoon 211A Kim, Jung Hye Roe. School of Biological Sciences, Seoul Cell wall architecture in wine yeast: Compositional and National University, Seoul, Korea. physiological analysis of yeast cell walls having varying impact on wine protein stability. Thulile Ndlovu, Florian 204C F. Bauer. Institute for Wine Biotechnology, Faculty of Evaluation of cytotoxicity caused by the strong AgriSciences, South Africa, Western Cape, South Africa. expression of GFPs with various localization signals. R. Kintaka, K. Makanae, H. Moriya. RCIS, Okayama University, City of Okayama, Japan.
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Poster Session Listings
212B Elucidating the Effects of Human Genetic Variation On Chromosome Dynamics: Vitamin D Signaling. Lauren Richardson, Jasper Rine. Centromeres QB3, University of California, Berkeley, Berkeley, CA.
213C The stress response pathway is activated in siw14 220A mutants. Elizabeth Steidle, Daisy Walker, Ronda J. Chromatin regulation of pericentric non-coding RNA in Rolfes. Biology, Georgetown University, Washington , S. cerevisiae affects chromosome stability. Julia Allison DC. Gallo, Jen Gallagher. Biology, West Virginia University, Morgantwon, WV. 214A Inducible and rapid depletion of proteins in S. 221B cerevisiae. Fabian Rudolf, Gintautas Vainorius, Moritz Dynamic Regulation of the Cnn1-Ndc80 Kinetochore Lang, Joerg Stelling. D-BSSE, ETH Zurich, 4058 Basel, 1 Interaction During Mitosis. Kriti Shrestha , Amanda Switzerland. Oldani2, Cinzia Pagliuca2, Peter De Wulf2, Tony Hazbun1. 1) Dept MCMP, Purdue Univ, West Lafayette, IN; 2) 215B European Institute of Oncology, Department of Changes in the sterol composition affect plasma- Experimental Oncology, Milan, 20139, Italy. membrane potential, intracellular pH and the activity of MDR pumps in Saccharomyces cerevisiae cells. Marie 222C Kodedova, Hana Sychrova. Dept Membrane Transport, Mechanisms for regulation of kinetochore protein levels Inst Physiology AS CR, Prague 4, Czech Republic. in budding yeast. Eva Herrero, Peter Thorpe. Stem Cell Biology and Developmental Genetics, National Institute for 216C Medical Research, London, United Kingdom. Selection for strains of Saccharomyces cerevisiae with enhanced Ochratoxin-A detoxification capabilities. 223A Aaron Welch. Chaplin School of Hospitality and Tourism, Regulation of centromeric nucleosome localization by Florida International University, North Miami, FL. 1,2 the E3 ubiquitin ligase Psh1. Erica Marie Hildebrand , Sue Biggins1. 1) Basic Sciences, Fred Hutchinson Cancer 217A Research Center, Seattle, WA; 2) Molecular and Cellular Identifying biomarkers of extended chronological Biology, University of Washington, Seattle, WA. lifespan through comparative gene expression profiling. Margaret B. Wierman, Mirela Matecic, Veena 224B Valsakumar, Daniel L. Smith, Stefan Bekiranov, Jeffrey S. Development of an in vitro kinetochore assembly assay Smith. Department of Biochemistry and Molecular to investigate kinetochore function and two alternate Genetics, University of Virginia, Charlottesville, VA. 1,2 1,2 assembly pathways. Jackie Lang , Sue Biggins . 1) Basic Sciences, Fred Hutchinson Cancer Research Center, 218B Seattle, WA; 2) Molecular and Cellular Biology, University An ER-Septin Diffusion Barrier Polarizes the of Washington, Seattle, WA. Endoplasmic Reticulum. Andrew K. O. Wong1, Jesse T. Chao1, Shabnam Tavassoli1, Barry P. Young1, Adam 225C Chruscicki2, Nancy N. Fang2,3, LeAnn J. Howe2, Thibault Molecular Basis of Deleterious Pericentric Mayor2,3, Leonard J. Foster2,3, Christopher J. R. Loewen1. Recombination during Meiosis. Mridula Nambiar, 1) Cellular and Physiological Sciences, University of Gerald Smith. Division of Basic Sciences, Fred Hutchinson British Columbia, Vancouver, British Columbia, Canada; Cancer Research Center, Seattle, WA. 2) Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada; 3) Centre for High-Throughput 226A Biology, University of British Columbia, Vancouver, Mutations in histones H3 and H4 define nucleosome British Columbia, Canada. regions essential for chromosome segregation. Payel Chaudhuri, Ines Pinto. Dept Biological Sciences, University of Arkansas, Fayetteville, AR. 219C Structural and functional analysis of Saccharomyces cerevisiae cell surface adhesins. N. Wozniak, H.-U. Mösch. Philipps University Marburg, Department of Genetics, Karl-von-Frisch-Straβe 8, 35043 Marburg, Germany.
29
Poster Session Listings
233B Chromosome Dynamics: The State of the Rfa2 N-Terminus Affects Rfa1-Protein Chromosome Structure Interactions that Map Outside of the Rfa1 N-Terminus. Kaitlin M. Dailey, Erica N. Mueller, Gunjan Piya, Stuart J. Haring. Chemistry and Biochemistry, North Dakota State University, Fargo, ND.
227B 234C The stromalin conservative domain in the Scc3 subunit The mismatch repair recognition complex MutS tracks of cohesin mediates the interaction with both Mcd1 and 1 1 with the replisome. Joanna E. Haye, Alison E. Gammie. the loading complex. Ola Orgil , Avi Matityahu , Thomas Dept Molec Biol, Princeton Univ, Princeton, NJ. Eng2, Vincent Guacci2, Douglas Koshland2, Itay Onn1. 1) Faculty of Medicine, Bar-Ilan University, Safed, Israel; 2) Molecular and Cell Biology Dept, University of California, 235A Berkeley, Berkeley, CA USA. Distinct Roles for the Rfa2 N-Terminus in the DNA Damage Response and Adaptation in Saccharomyces cerevisiae. Padmaja L. Ghospurkar1, Timothy M. 228C Wilson1, Amber L. Severson1, Sarah J. Klein2, Sakina K. Stability of a Large Amplification in Saccharomyces Khaku2, Andre P. Walther2, Stuart J. Haring1. 1) cerevisiae. Jamie Pogachar, Celia Payen, Maitreya Department of Chemistry and Biochemistry, North Dakota Dunham. Genome Sciences, University of Washington, State University, fargo, ND; 2) Biological Sciences, Cedar Seattle, WA. Crest College, Allentown,PA.
229A 236B Chromosome Breakage at Potential Fragile Sites in The application of glucose starvation as a selective force Retrotransposon Overdose Strains. Cristina M. 1 1 1 for the study of adaptive mutations in yeast. Maria Lanzillotta , Samantha Minikel , Nicholas Monteleone , 2 2 1 Hubmann, Petra Dorninger, Agnes Civegna, Erich Bracha Erlanger , Sarah J. Wheelan , Lisa Z. Scheifele . 1) Heidenreich. Institute of Cancer Research, Dep. of Department of Biology, Loyola University Maryland, Medicine I, Medical University of Vienna, Vienna, Austria. Baltimore, MD; 2) Department of Oncology, Division of Biostatistics and Bioinformatics, Center for Computational Genomics, Johns Hopkins School of Medicine, Baltimore, 237C MD. Volatility of mutator phenotypes at single cell resolution. Alan Herr, Scott Kennedy, Eric Schultz, Thomas Chappell, Gary Knowels, Brendan Kohrn. 230B Department of Pathology, University of Washington, Interface between a two-cohesin complex model of Seattle, WA. cohesion and DNA replication. Kevin Tong, Soumya Rudra, Robert V. Skibbens. Biological Sciences, Lehigh University, Bethlehem, PA. 238A An experimental system to investigate large-scale CAG/CTG trinucleotide repeat expansions. Jane C.
Kim, Samantha T. Harris, Kartik A. Shah, Sergei M. Chromosome Dynamics: Mirkin. Biology, Tufts University, Medford, MA. Mutagenesis/Repair 239B Stimulation of RNA Polymerase II ubiquitination by yeast RNA 3’ processing factors is a conserved DNA damage response in eukaryotes. Jason N. Kuehner1, 231C Hilary Duffy1, Claire Moore2. 1) Department of Biology, Systematic gene over-expression screen for increased Emmanuel College, Boston, MA; 2) Department of mutation rate in Saccharomyces cerevisiae. Jonathan S. Developmental, Molecular, and Chemical Biology, Tufts Ang1, Supipi Duffy1, Peter C. Stirling2, Phil Hieter1. 1) University School of Medicine, Boston, MA. University of British Columbia, Vancouver, Canada; 2) Terry Fox Laboratory, BC Cancer Agency, Vancouver, 240C Canada. Two structurally separable functions of Ctp1 in the early steps of DSB repair. L. Ma, M. Nambiar, N. 232A Milman, GR. Smith. Basic Science Division, Fred Suppression of the yeast DNA damage response gene Hutchinson Cancer Research Center, Seattle, WA. RTT107 by nonphosphorylatable H2A. Joshua A. R. Brown, Michael S. Kobor. Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver BC, Canada.
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Poster Session Listings
241A 247A Cancer-associated exosome mutations cause DNA:RNA Genomic screen for mutations conferring zeocin hybrids in yeast. K. Milbury1,2, Y. Chan3, V. Mathew1, P. hypersensitivity reveals diverse roles of vesicular Hieter2,3,4, P. Stirling1,2,4. 1) Terry Fox Laborotary, BC trafficking paths in genotoxic stress protection and in Cancer Research Centre, Vancouver, British Columbia, genome preservation. Kamil Krol1, Izabela Brozda1, Canada; 2) Genome Science and Technology, University of Marek Skoneczny2, Maria Bretner3, Adrianna British Columbia, Vancouver, British Columbia, Canada; Skoneczna1. 1) Laboratory of Mutagenesis and DNA 3) Michael Smith Laboratories, University of British Repair, Institute of Biochemistry and Biophysics, PAS, Columbia, Vancouver, British Columbia, Canada; 4) Warsaw, Poland; 2) Department of Genetics, Institute of Department of Medical Genetics, University of British Biochemistry and Biophysics, PAS, Warsaw, Poland; 3) Columbia, Vancouver, British Columbia, Canada. Faculty of Chemistry, Warsaw University of Technology, Warsaw, Poland. 242B Numerous extrachromosomal circular DNA elements in 248B Saccharomyces cerevisiae. Henrik D. Møller1, Lance Dynamic behavior of the CIN proteome in response to Parsons2, David Botstein2, Birgitte Regenberg1. 1) genotoxic stress. Veena Mathew1, Philip Hieter2, Peter C. Department of Biology, University of Copenhagen, Stirling1. 1) Terry Fox Laboratory, British Columbia Copenhagen, Copenhagen Ø, Denmark; 2) Lewis-Sigler Cancer Agency, Vancouver, BC, Canada; 2) Michael Smith Institute for Integrative Genomics, Princeton University, Laboratories, University of British Columbia, Vancouver, USA. BC, Canada.
243C 249C The Role of DNM1 in Mitochondrial Genome Stability Localization to the nuclear pore complex is required for in Budding Yeast. Christopher T. Prevost, Deanna stabilizing CAG repeats. Xiaofeng Su1, Vincent Dion2, Pedeville, Rey A. Sia. Dept. of Biology, The College at Susan M. Gasser3, Catherine H. Freudenreich1. 1) Biology, Brockport-SUNY, Brockport, NY. Tufts University, Medford, MA, USA; 2) Center for Integrative Genomics, University of Lausanne, Lausanne, 244A Switzerland; 3) Friedrich Miescher Institute for Biomedical Dbf4-dependent kinase regulates both spontaneous and Research, Basel, Switzerland. induced mutagenesis by binding to and phosphorylating the Rev7 subunit of DNA polymerase ζ. Robert A. 250A Sclafani1, Luis Brandão1, Rebecca Ferguson1, Irma Interchangeable Parts: Determining Rpa2 N-Terminal Santoro3,4, Sue Jinks-Robertson2,4. 1) Dept Biochem, Molec and Loop 3-4 Function through the Use of Gen, Univ Colorado Denver, Aurora, CO; 2) Department of Human/Yeast Rpa2 Hybrid Proteins. Timothy M. Molecular Genetics and Microbiology, Duke University Wilson, Kaitlin M. Dailey, Anna Herauf, Jenna Steffes, Medical Center, Durham, NC; 3) Department of Biology, Erica N. Mueller, Padmaja L. Ghospurkar, Stuart Haring. 7300 Reinhardt Circle, Reinhardt University, Waleska, GA; Chemistry and Biochemistry, North Dakota State 4) Department of Biology, Emory University, Atlanta, GA. University, Fargo, ND.
245B Structure-function analysis of the yeast ELG1 gene. Chromosome Dynamics: Keren Shemesh, Martin Kupiec. Department of Molecular Microbiology and Biotechnology, Tel Aviv Recombination University,Ramat Aviv, Israel.
246C The dark side of Swi6; genomic screen for mutants 251B hypersensitive to double strand breaks reveals Swi6 The role of nucleoporins, specifically Nup2, during indispensability for genome integrity and maintaining 1 1 meiosis in budding yeast. Daniel Chu, Sean Burgess. of cellular ploidy. Izabela Brozda , Paulina Adamus , MCB, UC Davis, Davis, CA. Kamil Krol1, Marek Skoneczny2, Adrianna Skoneczna1. 1) Laboratory of Mutagenesis and DNA Repair, Institute of Biochemistry and Biophysics, PAS, Warsaw, Poland; 2) 252C Department of Genetics, Institute of Biochemistry and Tethering of Meiotic Recombination Hotspots. Kyle R. Biophysics, Polish Academy of Science, Warsaw, Poland. Fowler, Gerry R. Smith. Fred Hutchinson Cancer Research Center, Seattle, WA.
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Poster Session Listings
253A Regulation, Weizmann Institute of Science, Rehovot, Activation of Holliday junction resolution via Israel. phosphorylation of Eme1 in meiosis. Randy W. Hyppa1, Pierre-Marie Dehé2, Pierre-Henri Gaillard2, Gerald R. 1 260B Smith . 1) Basic Sciences, Fred Hutchinson Cancer Characterizing the mechanism of variation in genomic Research Center, Seattle, WA; 2) Cancer Research Center uracil content . Debra Sue Bryan, Kerri York, Jay of Marseille, Marseille, France. Hesselberth. Biochemistry and Molecular Genetics, Univ Colorado School Medicine, Aurora, CO. 254B A potential novel mechanism for DNA double-strand 261C break repair pathway choice. Tatsuya Ii, Hiromi Ando, Genetic analyses of the Cdc24-Cds1 interaction in Melanie Alvarado, Miki Ii. Biological Sciences, University Schizosaccharomyces pombe. G. M. Guerrero, M. of Alaska Anchorage, Anchorage, AK. Nguyen, E. S. Sison, S. G. Pasion. Biology, San Francisco State University, San Francisco, CA. 255C Highly specific contractions of a single CAG/CTG 262A trinucleotide repeat by TALEN, in yeast. Guy-Franck The human Meier-Gorlin Syndrome mutation in ORC4 Richard, David Viterbo, Varun Khanna, Valentine reduces replication initiation and rDNA copy number in Mosbach, Bernard Dujon. Institut Pasteur, Paris, France. Saccharomyces cerevisiae. Joseph Carlo Sanchez, M. K. Raghuraman, Bonny Brewer. Genome Sciences, University 256A of Washington, Seattle, WA. Redefining the M26 hotspot. Walter Steiner, Chelsea Recor, Bethany Zakrzewski. Dept Biol, Niagara Univ, Lewiston, NY. Chromosome Dynamics: Telomeres 257B The Schizosaccharomyces pombe mitochondrial recombination junction- resolving enzyme is functionally homologous to Cce1p of Saccharomyces 263B cerevisiae. Stephan Zweifel, Cody Finke, Kristin Ku primarily impacts telomere length in Saccharomyces Andrykovich, Margaret Alexander, Jean Bower. cerevisiae via Est1 recruitment to the telomere. Laramie Department of Biology, Carleton College, Northfield, MN. Lemon1, Jaime Williams1, Faissal Ouenzar2, Pascal Chartrand2, Alison Bertuch1. 1) Department of Pediatrics, Baylor College of Medicine, Houston, TX; 2) Department Chromosome Dynamics: of Biochemistry, Université de Montréal, Quebec, Canada.
Replication 264C S. cerevisiae telomerase RNA, TLC1: two new essential functional features in addition to flexible scaffolding. K. J. Lebo, M. A. Mefford, R. O. Niederer, D. C. Zappulla. 258C Department of Biology, Johns Hopkins University, Autonomously replicating sequences from Baltimore, MD. Kluyveromyces marxianus apparently without canonical consensus. Babiker M. A. Abdel-Banat1,2, Hisashi Hoshida2, Rinji Akada2. 1) Dept. of Crop Protection, Chromosome Dynamics: University of Khartoum, Khartoum North, Sudan; 2) Dept. of Applied Molecular Bioscience, Yamaguchi University Transposition Graduate School of Medicine, Ube, Japan.
259A Tight coevolution of proliferating cell nuclear antigen 265A (PCNA)-partner interaction networks in fungi leads to Identification of cellular genes modulating Ty1 copy interspecies network incompatibility. Amir Aharoni1,2, 4 1 3 number control in Saccharomyces cerevisiae. Hyo Won Lyad Zamir , Inga Sandler , Eitan Rubin . 1) Department Ahn, David Garfinkel. Biochemistry & Molecular Biology, of Life Sciences, Ben-Gurion University, Beer-Sheva, University of Georgia, Athens, GA. Israel; 2) National Institute for Biotechnology in the Negev, Ben-Gurion University, Beer-Sheva, Israel; 3) Department of Microbiology and Immunology, Ben-Gurion University, Beer-Sheva, Israel; 4) Department of Biological
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Poster Session Listings
266B 271A A role for the budding yeast separase, Esp1, in Ty1 DNA replication and kinetochore mutants exhibit element transposition. Krystina Ho1,2, Lina Ma1, increased DNA:RNA hybrid formation. A. Chan1, P. Stephanie Cheung1,2, Nancy Fang2,3, Barry Young4, Hieter1,2. 1) University of British Columbia, Vancouver, Christopher Loewen4, Thibault Mayor2,3, Vivien BC, Canada; 2) Michael Smith Laboratories, Vancouver, Measday1,2. 1) Wine Research Centre, University of BC, Canada. British Columbia, Vancouver, British Columbia, Canada; 2) Department of Biochemistry and Molecular Biology, 272B University of British Columbia, Vancouver, British Dosage CIN genes: A comprehensive analysis of gene Columbia, Canada; 3) Centre for High-Throughput dosage effects on genome stability. Supipi Kaluarachchi Biology, University of British Columbia, Vancouver, Duffy, Sidney Ang, Phil Hieter. Michael Smith British Columbia, Canada; 4) Department of Cellular and Laboratories, University of British Columbia, Vancouver, Physiological Sciences, University of British Columbia, BC, Canada. Vancouver, British Columbia, Canada. 273C 267C Evidence that the extra dose of ACT1 causes slow Functional analysis of Ty1 Gag: trans-dominance and 1 growth in an aneuploid strain disomic for chromosome nucleic acid chaperone activity. Yuri Nishida , VI through a dosage imbalance with COF1. Alex Katarzyna Pachulska-Wieczorek2, Jessica Mitchell1, 2 1 Murphy, Keegan Gies, Kun Yang, Emma Kershisnik, Kirk Katarzyna J. Purzycka , David Garfinkel . 1) Biochemistry Anders. Biology Department, Gonzaga University, & Molecular Biology, University of Georgia, Athens, GA; Spokane, WA. 2) Polish Academy of Sciences, Institute of Bioorganic Chemistry, Poznan, Poland.
268A Gene Expression: Chromatin Regulation of sexual differentiation in Kluyveromyces lactis by endonuclease activity of the transposase- related gene KAT1. Naghmeh Rajaei, Kishore K. Chiruvella, Feng Lin, Stefan U. Åström. Department of 274A Molecular Biosciences, the Wenner-Gren Institute, Evolution of chromatin accessibility and gene Stockholm University, SE-10691 Stockholm, Sweden. expression levels during the heat shock response in Saccharomyces sensu stricto yeast. Caitlin Connelly, 269B Joshua Akey. Genome Sciences, University of Washington, A Trans-dominant form of Ty1 Gag mediates Copy Seattle, WA. Number Control of the Ty1 Retrotransposon in Saccharomyces. Agniva Saha, Jessica Mitchell, Yuri 275B Nishida, Jonathan Hildreth, David Garfinkel. Biochemistry A High-Resolution View Of Chromatin Architecture and Molecular Biology, University of Georgia, Athens, And Transcriptional Repression At Native Telomeres in GA. Saccharomyces cerevisiae. Aisha Ellahi, Deborah Thurtle, Jasper Rine. Dept of Molecular and Cell Biology, Univ California, Berkeley, Berkeley, CA. Chromosome Dynamics: Other 276C Investigations on the nature of a nucleosomal region
required for proper interactions between the transcription elongation factor Spt16 and transcribed 270C genes in S. cerevisiae. Paige Johnson, Jessalyn Tackett, A Tetraploid Intermediate Precedes Aneuploid Eugene Nyamugenda, Ryan Banning, Kelsi McClure, Formation in Yeasts Exposed to Fluconazole. Benjamin Martha Kellems, Harrison Lindley, Sarah Marshall, Harrison1, Maayan Bibi2, Rebecca Pulver2, Melanie 3 4 4 Andrea Duina. Biology Department, Hendrix College, Wellington , Jordan Hashemi , Guillermo Sapiro , Judith Conway, AR. G. Berman1,2. 1) Dept Mol Micro & Biotept Mol Micro & Biotechnol, Tel Aviv University, Ramat Aviv, Israel; 2) Department of Genetics, Cell Biology & Development, 277A Unversity of Minnesota, Minneapolis, MN; 3) Department Studies addressing a possible role for TORC1 in of Pediatrics, University of Rochester Medical Center, controlling chromatin structure and transcription elongation in S. cerevisiae.. Jasmine Haller1, Mary Rochester NY; 4) Department of Electrical and Computer 1 1 1 1 Engineering, Duke University, Durham, NC. Allison , Meet Modi , James Dornhoffer , Sarah Marshall , Taylor McElroy1, Marine Boucherle2, Anne Rufiange2, Malena Outhay1, Jennifer Harper1, Amine Nourani2, Andrea Duina1. 1) Biology Department, Hendrix College,
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Poster Session Listings
Conway, AR; 2) Centre de Recherche en Cancérologie de 284B l’Université Laval, L'Hotel-Dieu de Québec, Québec, A cre-lox recombination-based assay for the study of Canada. yeast chronological aging in nutrient-rich media conditions. David McCleary, Jasper Rine. UC Berkeley, 278B Berkeley, CA. Loss of transcriptional silencing is not an obligate precursor of yeast senescence. Gavin S. Schlissel, Jasper Rine. UC Berkeley, Berkeley, CA. Gene Expression:
279C Nucleo/Cytoplasmic Transport Keeping Quiet: Does heterochromatin stay silent during 1 homologous recombination? Katie Sieverman , Jasper Rine1,2. 1) Department of Molecular and Cell Biology, University of California - Berkeley, Berkeley, CA; 2) 285C California Institute for Quantitative Biosciences, University De novo amino acid biosynthesis influences starvation- of California - Berkeley, Berkeley CA. induced changes in tRNA distribution. Rebecca L. Hurto1,2, Anita K. Hopper1,2. 1) Molecular Genentics, Ohio State Univ, Columbus, OH; 2) The Center for RNA Gene Expression: Epigenetic Biology, OSU.
Mechanisms 286A The prion-like domain of the RNA-binding protein Ssd1 regulates the nuclear barcoding of Ssd1 to define its cytoplasmic destiny. Cornelia Kurischko, James R. 280A Broach. Biochemistry and Molecular Biology, College of Promoting a balanced acetylation state bypasses the Medicine, Penn State University, Hershey, PA. requirement for two essential NuA4 subunits in S. cerevisiae. Ana Lilia Torres-Machorro1,2, Naomi E. Frank Searle1,2,3, Lorraine Pillus1,2. 1) Section of Molecular Gene Expression: RNA processing Biology, Division of Biological Sciences University of California, San Diego, La Jolla, California 92093; 2) UC San Diego Moores Cancer Center, La Jolla, California 92093; 3) Biomedical Science Graduate Program, University of California, San Diego, La Jolla, California 287B 92093. Ribosome Subunit Biosynthesis Crosstalk During Repression of Ribosomal Protein Synthesis. Brian K. 281B Gregory, Lasse Lindahl. Biological Sciences, UMBC, Ubiquitin-mediated regulation of Snf1/AMPK by Ubp8 Baltimore, MD. and Ubp10 in budding yeast. Hsiang-En Hsu1, Tzu-Ning Liu2, Yi-Chen Lo2, Cheng-Fu Kao1. 1) Institute of Cellular 288C and Organismic Biology, Taipei, Taiwan; 2) Institute of Mitochondria outer membrane proteins are required Food Science and Technology, College of Bio-Resources for the proper function and localization of tRNA and Agriculture, National Taiwan University, Taipei, splicing endonucleases in Saccharomyces cerevisiae. Taiwan. Yao Wan1,2, Jingyan Wu1,2, Anita Hopper1,2. 1) Molecular Genetics, The Ohio State University, Columbus, OH; 2) 282C Center for RNA Biology, The Ohio State University, Accumulation of onco-metabolite 2-hydroxyglutarate Columbus, OH. impacts heterochromatin stability. Ryan Janke, Jasper Rine. Department of Molecular and Cell Biology and California Institute for Quantitative Biosciences, University Gene Expression: RNA turnover of California, Berkeley, CA 94720.
283A Synergistic repression of FLO11 and histone methylation by the Cyclin C/Cdk8 complex and histone 289A demethylase Jhd2p. Michael J. Law, Kerri Ciccaglione. Determination of in vivo RNA kinetics using RATE-seq. Rowan University-GSBS, Stratford, NJ. David Gresham, Benjamin Neymotin, Rodoniki Athanasiadou. Center for Genomics and Systems Biology, Department of Biology, New York University, New York, NY.
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Poster Session Listings
290B 296B Global analysis of 5'-hydroxyl RNA surveillance and Role of Chromosomal Looping in the Transcriptional turnover. Sally Peach, Kerri York, Jay Hesselberth. Regulation of Molecular Chaperone Genes in University of Colorado School of Medicine, Department of Saccharomyces cerevisiae. Surabhi Chowdhary, David Biochemistry and Molecular Genetics, Program in Gross. Biochemistry and Molecular Biology, Louisiana Molecular Biology, Aurora, CO. State University Health Sciences Center, Shreveport, LA.
291C 297C Genome-wide study of the interdependence between the Transciptional Profiling of Budding Yeast Biofilm cellular growth rate and mRNA turnover. J. Garcia- Suppressors. Gareth Cromie1, Zhihao Tan1,2, Eric Martinez2, G. Ayala3, D. A. Medina1, R. Gonzalez4, J. Jeffery1, Michelle Hays2, Cecilia Garmendia3, Aimée Warringer5, J. E. Perez-Ortin1. 1) Departamento de Dudley1,2. 1) Dudley Group, Pacific Northwest Diabetes Bioquimica y Biologia Molecular, Universitat de Valencia. Research Inst, Seattle, WA; 2) Molecular and Cellular Spain; 2) Departamento de Genetica, Universitat de Biology Program, University of Washington, Seattle, WA Valencia. Spain; 3) Departamento de Estadistica e USA; 3) Institut de Génétique et de Biologie Moléculaire et Investigacion Operativa, Universitat de Valencia. Spain; 4) Cellulaire, Strasbourg, France. Instituto de Ciencias de la Vid y del Vino. Logrono. Spain; 5) Department of Chemistry and Molecular Biology, 298A University of Gothenburg, Gothenburg, Sweden. Unanticipated complexity at the GAT1 locus. I. Georis1, R. Rai2, J. J. Tate2, T. G. Cooper2, E. Dubois1. 1) Institut de 292A Recherches Microbiologiques J.-M. Wiame, Brussels, Systematic Identification and Analysis of pre-mRNA Belgium; 2) Dept. Microbiology, Immunology and Splicing Regulators in Saccharomyces cerevisiae. H. Biochemistry, University of Tennessee Health Science Wang1,2, T. Chang1,2, M. Hwang1,2. 1) Academia Sinica, Center, Memphis, TN, USA. Taipei, Taiwan; 2) Genome and Systems Biology Degree Program, NTU, Taipei, Taiwan. 299B Selective interaction of RNA-binding proteins with transcript isoforms shapes the post-transcriptional life of mRNA. Ishaan Gupta1, Bernd Klaus2, Sandra Cluader- Gene Expression: Transcription Münster1, Aino Jäverlin1, Raeka Aiyar1, Vicente Pelechano1, Lars Steinmetz1,3,4. 1) 1European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Meyerhofstrasse 1, 69117 Heidelberg, Germany; 2) 293B European Molecular Biology Laboratory (EMBL), Centre In search of PP2A/Cdc55 targets involved in stress for Statistical Data Analysis, Meyerhofstrasse 1, 69117 induced transcription. Jessica Ferrari, Wolfgang Reiter, Heidelberg, Germany; 3) Stanford University School of David Hollenstein, Gustav Ammerer. Dept Biochem & Medicine, Department of Genetics, Stanford, CA 94305, Cell Biology, University of Vienna, Vienna, Austria. USA; 4) Stanford Genome Technology Center, 855 California Ave, Palo Alto, CA 94305, USA. 294C Regulation of stress induced gene expression in yeast. 300C Vasudha Bharatula1, Nils Elfving2, Razvan Chereji3, Spinning disk confocal microscopy of galactose- Stephan Bjorklund4, Alexandre Morozov3, James Broach1. responsive intra-nuclear clusters of the Gal80 protein in 1) Department of Biochemistry and Molecular Biology, live cells of Saccharomyces cerevisiae. James E. Hopper1,2, Sudip Goswami1, Onur Egriboz1, Kathleen Penn State College of Medicine, Hershey, PA 17033, USA; 1 2) Department of Medical Biochemistry and Biophysics, Dotts . 1) Dept Molecular Genetics, Ohio State Univ, Umeå University, Umeå 901 87, Sweden; 3) Department of Columbus, OH; 2) Dept of Chemistry and Biochemistry, Physics and Astronomy, Rutgers University, Piscataway, Ohio State Univ, Columbus OH. NJ 08854, USA; 4) BioMaPS Institute for Quantitative Biology, Rutgers University, Piscataway, NJ 08854, USA. 301A Controlling isoprenoid production using a 295A microaerobic-responsive switch in yeast. Hanxiao Jiang, Natural yeast promoter variants harbour different Robert Dahl, Adam Meadows. Amyris Inc. , 5885 Hollis levels of transcriptional-mediated noise. Jian Liu1, St. Suite 100, Emeryville, CA 94608. Marlène Vuillemin1, Hélène Martin-Yken1, Frédéric 2 2 1 Bigey , Sylvie Dequin , Jean-Marie François , Jean-Pascal 302B 1 Capp . 1) LISBP, INSA/Univ. of Toulouse, Toulouse, Changes in RNA Polymerase II catalytic activity France; 2) INRA, UMR 1083, Montpellier, France. influence transcription start site utilization on a global scale. H. Jin1, S. Schwartz2, I. Vvedenskaya3, I. Malik1, C. Qiu1, B. Nickels3, C. Kaplan1. 1) Department of
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Poster Session Listings
Biochemistry and Biophysics, Texas A&M University, 310A College Station, TX 77843, USA; 2) Texas Agrilife Analysis of ncDNA transcription for roles in regulating Research, Genomics and Bioinformatics, College Station, gene expression. Elizabeth A. Raupach1, Joseph TX, 77840, USA; 3) Waksman Institute, Rutgers Martens2. 1) Biological Sciences, University of Pittsburgh, University, Piscataway, New Jersey 08854, USA. PIttsburgh, PA; 2) Biology, Hamilton College, Clinton, NY. 303C CK2-dependent Regulation of Ifh1 Transcription 311B Factor Involved in the Expression of Ribosomal Protein Functional analysis of gene expression within the Genes. Myung Sup Kim, Ji-Sook Hahn. School of Lachancea kluyveri species. Christian Brion, David Chemical and Biological Engineering, Seoul National Pflieger, Joseph Schacherer. Department of Genetics and University. Genomics, University of Strasbourg, Strasbourg, France.
304A 312C Effect of Modulating the Level of the Seventh Largest Functional analysis of stress regulated non-coding Subunit of RNA Polymerase II in Schizosaccharomyces RNAs in budding yeast. Amanda N. Scholes, Tara N. pombe. Deepak Kumar, Nimisha Sharma. University Stuecker, Jeffery A. Lewis. Biological Sciences, University School of Biotechnology, G.G.S Indraprastha University, of Arkansas, Fayetteville, AR. Sec.16C, Dwarka, New Delhi, India-110078. 313A 305B FACS-based genetic screen in S. cerevisiae identifies DNA Replication Checkpoint Regulation of Cell-Cycle genes involved in the alpha-factor response. Anna Transcription Dynamics. Adam R. Leman1, Kevin A. Sliva1,2, Zheng Kuang1,2, Jef Boeke1,2. 1) High Throughput McGoff2, Xin Guo3, John Harer2, Steven B. Haase2. 1) Biology Center, Johns Hopkins University School of Biology, Duke University, Durham, NC; 2) Mathematics, Medicine, Baltimore, MD 21205; 2) New York University Duke University, Durham, NC; 3) Statistical Sciences, Langone Medical Center, New York, NY 10016. Duke University, Durham, NC. 314B 306C Adaptive evolution of transcription and translation in The thiamine signal transduction pathway in Candida pathogenic yeast. Xuepeng Sun1,2, Zhe Wang1, Zhenglong glabrata. Sarah Grace Leone, Nicholas Attanasio, Gu1. 1) Division of nutritional sciences, Ithaca, NY; 2) Michael Peel, Christine Iosue, Dennis Wykoff. Biology, College of Agriculture and Biotechnology. Villanova University, Villanova, PA. 315C 307A PRS gene family - a means of linking primary Transcriptional Regulation of HAP4 by the Mediator metabolism and cell signalling. Eziuche Amadike Complex and Adenine Levels in Saccharomyces Ugbogu, Lilian Marry Schweizer, Michael Schweizer. cerevisiae. Chad Bush, Denise Capps, Mengying Chiang, Biochemistry, Heriot-watt University, Edinburgh, United Tammy Pracheil, Zhengchang Liu. Dept. of Biological Kingdom. Sciences, University of New Orleans, 2000 Lakeshore Drive, New Orleans, LA 70148. 316A S. cerevisae rRNA Synthesis by RNA Polymerase (Pol) 308B II in Response to Nitrogen Deprivation. Arjuna Rao Loss of Ubp3 increases Silencing, decreases Unequal Vallabhaneni, Merita Kabashi, Kushal Bhatt, Heather Recombination in rDNA, and shortens the Replicative Conrad-Webb. Biology, Texas Woman's University, Life Span in Saccharomyces cerevisiae. David Oling, Denton, TX. Rehan Masoom, Kristian Kvint. Chemistry and Molecular Biology, Medicinaregatan 9C, 41390, University 317B Gothenburg, Sweden. Systematic analysis of RNA polymerase III and TFIIIB phosphoregulation in Saccharomyces cerevisiae. Jaehoon 309C Lee, Robyn D. Moir, Ian M. Willis. Department of Phenotypic landscape of the conserved and essential Biochemistry, Albert Einstein College of Medicine, Bronx, RNA Polymerase II trigger loop: a high-throughput NY. structure-function analysis. Chenxi Qiu, Olivia Erinne, Ping Cui, Kenny Lam, Sabareesh Babu, Huiyan Jin, Alvin 318C Tang, Nandhini Mutukrishnan, Craig Kaplan. Defining the transcriptome of Saccharomyces cerevisiae. Biochemistry&Biophysics, Texas A&M University, Janos Demeter, Paul Lloyd, Edith Wong, J. Michael College Station,TX. Cherry. Department of Genetics, Stanford University, Palo Alto, CA.
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Poster Session Listings
319A Tamara Wriessnegger1, Erich Leitner2, Monika Müller3, Dissection of the PHO pathway in S. pombe using Iwona Kaluzna3, Martin Schurmann3, Daniel Mink3, epistasis and the alternate repressor adenine. Molly S. Guenther Zellnig4, Harald Pichler1,5. 1) ACIB GmbH, Estill, Christine L. Iosue, Dennis D. Wykoff. Dept Biol, Petersgasse 14, 8010 Graz, Austria; 2) Institute of Villanova Univ, Villanova, PA. Analytical Chemistry and Food Chemistry, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria; 3) 320B DSM Innovative Synthesis B.V., Urmonderbaan 22, 6167 Accumulation of a threonine biosynthetic intermediate RD Geleen, The Netherlands; 4) Institute of Plant Sciences, attenuates general amino acid control by inducing University of Graz, Schubertstrasse 51, 8010 Graz, Austria; degradation of promoter-bound Gcn4. FNU Yashpal, 5) Institute of Molecular Biotechnology, Graz University of Hongfang Qiu, Alan G. Hinnebusch. Laboratory of Gene Technology, Petersgasse 14/2, 8010 Graz, Austria. Regulation and Development, Eunice Kennedy Shriver National Institute of Child Health and Human 326B Development, National Institutes of Health, Bethesda, Mutants defective in stress granule formation exhibit a Maryland 20892. deregulated stress response. Elena Garre1, Xiaoxue Yang2, Yi Shen2, Xinxin Hao1, Daniel Krumlinde1, Marija 3,4 1 1 Cvijović , Christina Arens , Thomas Nyström , Beidong Liu1,2, Per Sunnerhagen1. 1) Department of Chemistry and Gene Expression: Translation Molecular Biology, University of Gothenburg, Göteborg, Sweden; 2) School of Life Science and Engineering, Harbin Institute of Technology, Harbin, China; 3)
Department of Mathematical Sciences, Chalmers University of Technology, Göteborg, Sweden; 4) 321C Department of Mathematical Sciences, University of Codon Context and Translation Efficiency in Yeast. Gothenburg, Göteborg, Sweden. Caitlin E. Gamble1, Christina Brule2, Stanley Fields1,3, Elizabeth Grayhack2. 1) Genome Sciences, University of Washington, Seattle, WA; 2) University of Rochester 327C School of Medicine and Dentistry, Rochester, NY; 3) Securing autoselection in yeast ACNase killer toxin Howard Hughes Medical Institute. systems by mRNA fragmentation. Alene Kast, Friedhelm Meinhardt. Institute of Molecular Microbiology and Biotechnology, University of Münster, Corrrensstr. 3, 322A 48149 Münster, Germany. Functional alnalysis of CaMCA1 and EDC3 in oxidative stress response and apoptotic cell death in Candida albicans. Jeong-Hoon Jeong, Jong-hwan Jung, Jinmi Kim. 328A Gene copy number and colony morphology in wild Department of Microbiology and Molecular biology, 1 3 Chungnam National University, Daejeon, South Korea. yeast strains. Derek Wilkinson , Vratislav Stovicek , Libuse Vachova2, Zdena Palkova1. 1) Department of Genetics and Microbiology, Faculty of Science, Charles 323B University in Prague, Vinicna 5, 128 44 Prague 2, Czech Roles of decapping activators in mRNA translation and Republic; 2) Institute of Microbiology of the ASCR, v.v.i., P-body formation during mating. Daehee Jung, Yuseon Videska 1083, 142 20 Prague 4, Czech Republic; 3) The Lee, Jinmi Kim. Department of Microbiology and Novo Nordisk Foundation Center for Biosustainability, Molecular Biology, Chungnam National University, Technical University of Denmark, Kogle Alle 6, 2970 Daejeon, South Korea. Hørsholm, Denmark.
324C 329B Evolutionary Divergence of the Stress Response at the Chaperonins enabled functional expression of bacterial Translational Level. Pieter J. Spealman, Alan Shteyman, xylose isomerases in yeast. Jianjun Yang1, Min Qi1, Charles McManus. Biological Sciences, Carnegie Mellon Kristen Kelly1, Sarah Rush2, Luan Tao2, Rick Ye1, Paul University, PITTSBURGH, PA. Viitanen2, William Hitz2. 1) Biotechnology, DuPont Central Research and Development, Experimental Station, Wilmington, DE; 2) DuPont Industrial Biosciences, Gene Expression: Other Experimental Station, Wilmington, DE.
330C Dissecting the mechanism of gene-dosage response in naturally aneuploid, wild isolates of Saccharomyces 325A cerevisiae. Mun Hong Yong1, James Hose1, Audrey Improving heterologous cytochrome P450 function in S. Gasch1,2. 1) Laboratory of Genetics, University of 1 1 cerevisiae. Anita Emmerstorfer , Miriam Wimmer , Wisconsin-Madison, Madison, WI; 2) Genome Center of
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Poster Session Listings
Wisconsin, University of Wisconsin-Madison, Madison, 337A WI. Emergence of Novel Ecological Interactions in an Evolving Cooperative Community. Robin Green1,2, 1 1 1 Chichun Chen , Jose Pineda , Wenying Shou . 1) Fred Hutchinson Cancer Research Center, Seattle, WA; 2) Global Analysis: Molecular and Cellular Biology Program, University of Evolution/Comparative Genomics Washington, Seattle, WA.
338B
Tracking the genetic factors of Saccharomyces cerevisiae strains under the selective pressures of the 331A beer brewing process. Noah A. Hanson, Celia Payen, Rerouting resources from cell size to population growth Maitreya Dunham. Genome Sciences, University of drives evolution of cancer drug resistance in yeast. E. Washington, Seattle, WA. Alonso-Perez1, N. Srinivas1, M. Kakavandi1, K. Ludwig1, I. Jonassen2, SW Omholt3, P. Sunnerhagen1, J. Warringer1. 1) Department of Chemistry & Molecular Biology, 339C University of Gothenburg. Gothenburg, Sweden; 2) Uni Ploidy-regulated variation in biofilm-related Computing, Uni Research AS, Bergen, Norway ; phenotypes in natural isolates of Saccharomyces Department of Informatics, University of Bergen, Bergen, cerevisiae. Elyse A. Hope, Maitreya J. Dunham. Norway; 3) Center for Integrative Genetics (CIGENE), Department of Genome Sciences, University of Norwegian University of Life Sciences (UMB), Ås, Washington, Seattle, WA. Norway. 340A 332B A two loci genetic incompatibility leads to offspring Inferring Genetic Networks through Evolutionary respiratory deficiency within the Saccharomyces Signatures. Zelia Ferreira1, Jennifer Walker1, Allyson cerevisiae species. Jing Hou, Anne Freidrich, Joseph O'Donnell2, Nathan Clark1. 1) Computational and Schacherer. Laboratoire de génétique moléculaire, Systems Biology, University of Pittsburgh, PA; 2) génomique et microbiologie, Université de Department of Cell Biology, University of Pittsburgh, PA. Strasbourg/CNRS UMR7156, Strasbourg, France.
333C 341B The mating pathway as a model for the genetic analysis Site-directed changes to CgPMU1 convert it into a of complex traits. Michael W. Dorrity1,2, Josh T. broad range acid phosphatase like CgPMU2 in Candida Cuperus2,3, Christine Queitsch2, Stanley Fields2,3. 1) glabrata. Christine L. Iosue, Kelly A. Orlando, Sarah G. Department of Biology, University of Washington, Seattle, Leone, Danielle L. Davies, Dennis D. Wykoff. Biol Dept, WA; 2) Department of Genome Sciences, University of Villanova Univ, Villanova, PA. Washington, Seattle, WA; 3) Howard Hughes Medical Institute, University of Washington, Seattle, WA. 342C Why do some yeast species have duplicate copies of GALactose network genes? Meihua Christina Kuang1,2, 334A 1,2 Functional Evolution of SIR1 In Saccharomyces Chris Hittinger . 1) Laboratory of Genetics, University of cerevisiae And Related Budding Yeasts. Aisha Ellahi, Wisconsin-Madison, Madison, WI; 2) Graduate Program in Jasper Rine. Dept MCB, Univ California, Berkeley, Cellular and Molecular Biology, University of Wisconsin- Berkeley, CA. Madison, WI.
335B 343A Microevolution of a human fungal pathogen in a mouse Single-cell analysis reveals natural variability in a model of systemic infection. Iuliana Ene1, Matthew potential bet-hedging trait. Colin S. Maxwell, Paul Hirakawa1, Emily Mallick1, Christina Cuomo2, Richard Magwene. Department of Biology, Duke University, Bennett1. 1) Molecular Microbiology and Immunology, Durham, NC. Brown University, Providence, RI; 2) Broad Institute, Cambridge, MA. 344B Combining natural sequence variation with high 336C throughput mutational data to reveal protein interaction sites. Daniel Melamed1,2, David Young2, Phenotypic and Mitochondrial Haplotype Variation in a 1,2 1,2,3 Local Population of Wild Yeasts. Raymond A. Futia, Christina Miller , Stanley Fields . 1) Howard Hughes Abigail P. Weinberg, Mei-Yi Zheng, Heather L. Fiumera. Medical Institute; 2) Department of Genome Sciences, Department of Biological Sciences, Binghamton University of Washington; 3) Department of Medicine, University, Binghamton, NY. University of Washington.
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Poster Session Listings
345C 351C Transport differences in two recently high affinity HXT Natural variation in mutational robustness among paralogous. A. Mena1,2, E. Barrio1, F. N. Arroyo-López3. strains of Saccharomyces cerevisiae. Marcin Plech1, J. 1) University of Valencia Calle Doctor Moliner, 50, 46100 Arjan G. M. de Visser2, Ryszard Korona1. 1) Institute of Burjasot, Valencia; 2) IATA-CSIC Institute of Environmental Sciences, Department of Biology, Agrochemistry and Food Technology Carrer Catedràtic Jagiellonian University, Kraków, Poland; 2) Genetics Lab, Agustín Escardino Benlloch, 7, 46980 Paterna, València; 3) Plant Sciences Group, University of Wageningen, The CSIC Instituto de la Grasa, Department of Food Netherlands. Biotechnology Av Padre García Tejero, 4, 41012 Sevilla. 352A 346A Genetic variation acting on protein translation and Novelty by necessity: Loss of sulfate transport in yeast degradation rates is common in Saccharomyces repeatedly selects for mutations in an uncharacterized cerevisiae. Daniel Pollard, Homa Rahnamoun, Scott transporter YIL166C in sulfate-limited environments. Rifkin. Biological Sciences, UCSD, La Jolla, CA. Aaron W. Miller, Ivan Liachko, Anna B. Sunshine, Maitreya J. Dunham. Genome Sciences, University of 353B Washington, Seattle, WA. Genome-wide patterns of genetic variation reveal chromosome-scale heterogeneous evolution in a 347B protoploid yeast. Anne Friedrich1, Paul Jung1, Cyrielle The Genetic Architecture of Invasive Growth in a Reisser1, Gilles Fischer2,3, Joseph Schacherer1. 1) Clinical Isolate of S. cerevisiae. Helen A. Murphy1,2, Department of Genetics and Genomics, University of Debra Murray2, Jason Smyth3, Cliff W. Zeyl3, Paul M. Strasbourg, Strasbourg, France; 2) Sorbonne Universités, Magwene2. 1) Biology, William and Mary, Williamsburg, UPMC Univ Paris 06, UMR 7238, Biologie VA; 2) Biology, Duke University, Durham, NC; 3) Computationnelle et Quantitative, Paris, France; 3) CNRS, Biology, Wake Forest University, NC. UMR7238, Biologie Computationnelle et Quantitative, Paris, France. 348C Mitochondrial-Nuclear Epistasis and Coevolution in 354C Natural Isolates of Saccharomyces cerevisiae. Swati Genome sequence and evolution of Saccharomyces Paliwal, Anthony C. Fiumera, Heather L. Fiumera. carlsbergensis, the world’s first pure culture lager yeast. Biological Sciences, Binghamton University, State Andrea Walther, Ana Hesselbart, Jurgen W. Wendland. University of New York, Binghamton, NY 13902. Yeast Genetics, Carlsberg Laboratory, Copenhagen V, Denmark. 349A Investigating reticulate evolution in the Saccharomyces 355A genus and repeating it for the bioethanol industry. Evolutionary Exploration of Yeast Hap4p Regulatory David Peris Navarro1,2, Kayla Sylvester1, Maria Sardi1, Networks. Ruoyu Zhang, Xiaoxian Guo, Zhenglong Gu. William Alexander1,2, Diego Libkind3, Paula Gonçalves4, Division of Nutritional Science, Cornell University, Ithaca, José Sampaio4, Lucas Parreiras2, Trey Sato2, Chris NY. Hittinger1,2. 1) Department of Genetics, Genome Center of Wisconsin, University of Wisconsin-Madison, WI; 2) Wisconsin Energy Institute, DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, WI; 3) Global Analysis: Genomics Laboratorio de Microbiología Aplicada y Biotechnología, Instituto de Investigaciones en Biodiversidad y Medio- ambiente, INIBIOMA (CONICET-UNComahue), Bariloche, Argentina; 4) Centro de Recursos 356B Microbiológicos, Departamento de Ciências da Vida, The yeast phenome: mapping the functional Faculdade de Cieências e Tecnologia, Universidad Nova de organization of a eukaryotic cell through an integrative Lisboa, Caparica, Portugal. study of genome-wide phenotypic surveys. Anastasia Baryshnikova1, Monica Sanchez2, Maitreya Dunham2. 1) 350B Lewis-Sigler Institute for Integrative Genomics, Princeton ‘’Natural and experimental evolutionary dynamics of University, Princeton, NJ; 2) Department of Genome Saccharomyces killer yeast’’. Magdalena Pieczynska1,2, Sciences, University of Washington, Seattle, WA. Ryszard Korona2, J. Arjan G. M. de Visser1. 1) Laboratory of Genetics, Plant Sciences Group, Wageningen, 357C Netherlands; 2) Institute of Environmental Sciences, Multiplexed genome engineering in Saccharomyces Jagiellonian University, Gronostajowa 7, Kraków, Poland. cerevisiae. Josh Cuperus1,2, Russel Lo1,2, Stanley Fields1,2. 1) Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA; 2) Howard Hughes
39
Poster Session Listings
Medical Institute, University of Washington, Seattle, Life and Environmental Sciences, Exeter, UK; 4) Tel-Aviv Washington 98195, USA. University, Department of Molecular Microbiology and Biotechnology, Tel-Aviv, Israel. 358A WITHDRAWN 364A A higher-throughput accurate method for unraveling 359B the genetic basis of Chronological Life Span in yeast. Paul P. Jung1, Nils Christian1, Daniel Kay1, Aimée M. Multiple global approaches for deciphering the 2 1 1 molecular basis of low temperature adaptation in wine Dudley , Alexander Skupin , Carole L. Linster . 1) yeast. Estéfani García-Ríos1, María López-Malo1,2, José University of Luxembourg, Luxembourg Centre for Manuel Guillamón1. 1) Departamento de Biotecnología de Systems Biomedicine, Esch-sur-Alzette, Luxembourg; 2) los alimentos, Instituto de Agroquímica y Tecnología de los Pacific Northwest Diabetes Research Institute, Seattle. Alimentos (CSIC), Avda. Agustín Escardino, 7, E-46980- Paterna , Valencia, Spainlencia, Valencia, Spain; 2) 365B Biotecnologia Enològica. Departament de Bioquímica i Evidence that mutation accumulation does not cause Biotecnologia, Facultat de Enologia, Universitat Rovira i aging in Saccharomyces cerevisiae. Alaattin Kaya, Virgili. Marcel•li Domingo s/n, 43007, Tarragona, Spain. Alexei V. Lobanov, Vadim N. Gladyshev. Medicine, Harvard University, Boston, MA. 360C Expression adaptation and gene-dosage response in 366C naturally aneuploid strains of wild S. cerevisiae. James Pooled Segregant Sequencing Reveals Genetic Hose1, Chris Yong1, Zhishi Wang2, Michael A. Newton2, Determinants of Yeast Pseudohyphal Growth. Qingxuan Audrey P. Gasch1. 1) Laboratory of Genetics & Genome Song1, Cole Johnson1, Thomas Wilson2, Anuj Kumar1. 1) Ctr, U. Wisconsin-Madison, Madison, WI; 2) Departments Dept. of Mol., Cell., and Dev. Biology, University of of Statistics & Biostatistics & Medical Informatics, U. Michigan, Ann Arbor, MI; 2) Dept. of Pathology, Wisconsin-Madison, Madison, WI. University of Michigan Medical School, Ann Arbor, MI.
361A 367A MKT1 interacts with nitrogen metabolism and Genetic Incompatibilities in Hybrid Yeast. Samuel M. mitochondrial signaling pathways to modulate Lancaster, Miatreya J. Dunham. Genome Sciences, sporulation efficiency variation. Saumya Gupta1, University of Washington, Seattle, WA. Aparna Radhakrishnan1, Julien Gagneur2, Himanshu 1 Sinha . 1) Department of Biological Sciences, Tata Institute 368B of Fundamental Research, Mumbai 400005, India; 2) Gene An Evaluation of High-Throughput Approaches to Center Munich, Department of Biochemistry, Ludwig QTL Mapping in Saccharomyces cerevisiae. Stefan Maximilians University, 81377 Munich, Germany. Wilkening1, Gen Lin1, Emilie Fritsch1, Manu Tekkedil1, Simon Anders1, Rauel Kuehn2, Michelle Nguyen2, Raeka 362B Aiyar1, Michael Proctor2, Nikita Sakhaneko3, David Identification of novel pathways involved in ploidy Galas3,4, Julien Gagneur3, Adam Deutschbauer5, Lars maintenance in Saccharomyces cerevisiae. P. S. Hung1,2, Steinmetz1. 1) European Molecular Biology Laboratory, T. L. Sing1,2, S. Ohnuki3, B. San-Luis2,4, J. Paw2,4, M. Genome Biology Unit, 69117 Heidelberg, Germany; 2) Costanzo2,4, C. Nislow5, C. Boone2,4, Y. Ohya3, G. W. Stanford Genome Technology Center, Palo Alto, California Brown1,2. 1) Department of Biochemistry, University of 94304; 3) Pacific Northwest Diabetes Research Institute, Toronto, Toronto, Ontario, Canada; 2) Donnelly Centre for Seattle, Washington 98122; 4) Luxembourg Centre for Cellular and Biomolecular Research, University of Systems Biomedicine, University of Luxembourg, L-4362, Toronto, Toronto, Ontario, Canada; 3) Department of Esch-sur-Alzette, Luxembourg; 5) Physical Biosciences Integrated Biosciences, University of Tokyo, Tokyo, Japan; Division, Lawrence Berkeley National Laboratory, 4) Department of Molecular Genetics, University of Berkeley, California 94720. Toronto, Toronto, Ontario, Canada; 5) Department of Pharmaceutical Sciences, University of British Columbia, 369C Vancouver, British Columbia, Canada. An Assessment of Terminal Phenotypes in S. cerevisiae Using Synthetic Genetic Array and High-Content 363C Screening. Dara Lo1, Jason Moffat1,2, Brenda Andrews1,2, Cost-effective Genotyping and Karyotyping Using Charles Boone1,2. 1) Molecular Genetics, University of Double Digest-RAD Sequencing in S. cerevisiae, C. Toronto, Toronto, Ontario, Canada; 2) Donnelly Centre for albicans and C. glabrata. E. Jeffery1, G. Cromie1, A. Cellular and Biomolecular Research, University of Forche2, J. Usher3, K. Haynes3, J. Berman4, A. M. Dudley1. Toronto, Toronto, Ontario, Canada. 1) Pacific Northwest Diabetes Research Inst, Seattle, WA. USA; 2) Bowdoin College, Department of Biology, Brunswick, ME. USA; 3) University of Exeter, College of
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Poster Session Listings
370A 375C Beyond Beer and Wine: Isolating Wild Yeast from Comparative analysis of stress responses in diverse wild Unroasted Cacao and Coffee Beans. Catherine Ludlow1, yeast strains. Nikolay S. Rovinskiy1,2, Dana J. Cecilia Garmendia Torres2, Amy Sirr1, Michelle Hays3, Wohlbach1,2, Jeff Lewis1,2, Maria I. Sardi1,2, Wendy S. Colby Field4, Gareth Cromie1, Eric W. Jeffery1, Aimée M. Schackwitz3, Joel A. Martin3, Shweta Deshpande3, Chris Dudley1,3. 1) Pacific Northwest Diabetes Research Institute, Daum3, Trey K. Sato2, Audrey P. Gasch1,2. 1) Genetics, Seattle, Washington, USA; 2) Institut de génétique et de University of Wisconsin-Madison, Madison, WI; 2) Great biologie moléculaire et cellulaire, Strasbourg, France; 3) Lakes Bioenergy Research Center; Madison, Wisconsin Molecular and Cellular Biology Program, University of 53706; 3) US Department of Energy Joint Genome Washington, Seattle, WA USA; 4) Montana State Institute; Walnut Creek, California 94598. University, Bozeman, Montana, USA. 376A 371B Chromatin organization in quiescent yeast. Mark T. Exploring the endocytic pathway by combining high- Rutledge1,2, Jon-Matthew Belton3, Mariano Russo2, Job throughput genetics and high-content microscopy. Dekker3, James R. Broach2. 1) Dept. of Molecular Biology, Mojca Mattiazzi Usaj1, Matej Usaj1, Marinka Zitnik2, Princeton University, Princeton, NJ; 2) Dept. of Blaz Zupan2, Brenda Andrews1, Charles Boone1. 1) The Biochemistry and Molecular Biology, Pennsylvania State Donnelly Centre, University of Toronto, Toronto, Ontario, University College of Medicine, Hershey, PA; 3) Program Canada; 2) Faculty of Computer and Information Science, in Systems Biology, Dept. of Biochemistry and Molecular University of Ljubljana, Ljubljana, Slovenia. Pharmacology, University of Massachusetts Medical School, Worcester, MA. 372C Navigating the chemical space of large compound 377B libraries using high-throughput chemical genomics. Jeff Genomic approaches to understanding Saccharomyces Piotrowski1, Sheena Li2, Raamensh Deshpande3, Scott cerevisiae tolerance to lignocellulosic-hydrolysate Simpkins3, Justin Nelson3, Jacqueline Barber2, Hiroyuki toxins. Maria I. Sardi, Dana J. Wohlbach, Audrey P. Osada2, Minoru Yoshida2, Chad Myers3, Charlie Boone4. 1) Gasch. University of Wisconsin-Madison, Madison, WI. Great Lakes Bioenergy Research Centre University of Wisconsin - Madison, USA 53726; 2) Center for 378C Sustainable Resource Science, RIKEN, 2-1 Hirosawa, A phenomic assessment of sub-cellular morphology in Wako, Saitama, Japan 351-0198; 3) Department of S. cerevisiae using Synthetic Genetic Array analysis and Computer Science and Engineering, University of high-content screening. Erin B. Styles1, Lee Zamparo1, Minnesota, Minneapolis, MN 55455, USA; 4) 4.Banting Karen Founk1, Oren Kraus1,2, Dogus Altintas3, Marco and Best Department of Medical Research and Department Graf4, Daniele Novarino5, Tina Sing1, Grant W. Brown1, of Molecular Genetics, Donnelly Centre, University of Marco Muzi-Falconi5, Brian Luke4, David Shore3, Brendan Toronto, 160 College St., Toronto, ON, Canada M5S 3E1. Frey2, Zhaolei Zhang1, Charles Boone1, Brenda J. Andrews1. 1) Donnelly Centre for Cellular and 373A Biomolecular Research, University of Toronto, Toronto, Transcriptional and post-transcriptional analyses of the ON, Canada; 2) Electrical and Computer Engineering, iron deficiency response in Saccharomyces cerevisiae. University of Toronto, Toronto, ON, Canada; 3) Antonia Maria Romero1, Daniel A. Medina2, Jose García- Department of Molecular Biology, NCCR Program Martinez3, M.Teresa Martínez-Pastor2, Jose E. Pérez- "Frontiers in Genetics", and Institute of Genetics and Ortín2, Sergi Puig1. 1) 1Departamento de Biotecnología, Genomics in Geneva, 30 quai Ernest Ansermet, CH-1211 Instituto de Agroquímica y Tecnología de Alimentos Geneva 4, Switzerland; 4) DKFZ-ZMBH Alliance, (IATA) Consejo Superior de Investigaciones Científicas University of Heidelberg, Im Neuenheimer Feld 282, (CSIC), Paterna, Valencia, E-46100, Spain; 2) Department 69120 Heidelberg, Germany; 5) Dipartimento di of Biochemistry and Molecular Biology. Universitat de Bioscienze Universita' degli Studi di Milano, Milano, Italy. València. Ave. Doctor Moliner, 50; E-46100 Burjassot (Valencia) Spain; 3) Department of Genetics. Universitat 379A de València. Ave. Doctor Moliner, 50; E-46100 Burjassot Genetic basis for Saccharomyces cerevisiae biofilm in (Valencia) Spain. liquid medium. Kaj S. Andersen1, Laura G. R. Sørensen1, Rasmus Bojsen2,3, Martin W. Nielsen2,3, 374B Michael Lisby1, Anders Folkesson2,3, Birgitte Regenberg1. Transcriptional variations among Saccharomyces 1) Department of Biology, University of Copenhagen, cerevisiae strains harboring different alleles of a Copenhagen, Denmark; 2) Department of Systems Biology, transcription factor Yrr1. Xiaoqing Rong-Mullins1, Wei Technical University of Denmark, Copenhagen, Denmark; Zheng2, Hogune Im2, Erin Mitsunaga2, Michael Snyder2, 3) National Veterinary Institute, Technical University of Jennifer Gallgher1. 1) Biology, West Virginia University, Denmark, Copenhagen, Denmark. Morgantown, WV; 2) Genetics, Stanford University, Stanford, CA.
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Poster Session Listings
380B Pharmacology, Dalhousie University, Halifax, Nova Scotia, An all-in-one yeast library - creating a new toolbox for Canada. studying the proteome. Uri Weill, Ido Yofe, Maya Schuldiner. Department of Molecular Genetics, Weizmann 387C Institute of Science, Rehovot, Israel. Yeast - it simply has a lot to say about human disease. Selina S. Dwight, Kalpana Karra, J. Michael Cherry, SGD Project. Department of Genetics, Stanford University Global Analysis: Human School of Medicine, Stanford, CA 94305.
Diseases/Drug Discovery 388A Deep mutational scanning of amyloid β to illuminate mechanisms of protein aggregation and chaperone interactions. Vanessa E. Gray, Jason J. Stephany, 381C Douglas M. Fowler. Genome Sciences, School of Medicine Establishing the yeast as a model for human disease. at the University of Washington, Seattle, WA, USA. Neta Agmon, Leslie Mitchell, Jef Boeke. Bioch & Mol Pharm, Institute of Systems Genentics, NYU Langone 389B Medical Center, New York, NY. Solving protein structure with large-scale mutagenesis. Katherine A. Sitko, Douglas M. Fowler, Margaret L. 382A Griset. Genome Sciences, School of Medicine at the Mapping resistance to targeted cancer therapeutics University of Washington, Seattle, WA. using a deep mutational scanning approach in Saccharomyces cerevisiae. Ethan Ahler, Douglas Fowler. 390C Department of Genome Sciences, University of Systematic identification of human/yeast cross-species Washington, Seattle, WA. complementation pairs. Akil Hamza, Phil Hieter. Michael Smith Laboratories, University of British 383B Columbia, Vancouver, British Columbia, Canada. Synthetic dosage lethality of CTF4 and the identification of orthologs amplified in breast cancer. 391A 1 2 2 Eric Bryant , John Dittmar , Robert J. D. Reid , Rodney Anticancer ruthenium complex KP1019 induces the Rothstein2. 1) Biological Sciences, Columbia University, heat shock response in yeast. Laura Stultz1, Alexandra New York, NY 10027; 2) Genetics and Development, Hunsucker2, Evan Grovenstein2, James Mobley3, Pamela Columbia University Medical Center, New York, NY Hanson2. 1) Chemistry Department, Birmingham-Southern 10032. College, Birmingham, AL; 2) Biology Department, Birmingham-Southern College, Birmingham, AL; 3) Mass 384C Spectrometry/Proteomics Facility, University of Alabama Identification of biological roles for yeast Rbd2, a at Birmingham, Birmingham, AL. member of a subfamily of rhomboid proteins implicated 1 in human disease. Christa L. Cortesio , Eric B. 392B 1 1 2 Lewellyn , Nathaniel I. Krefman , Catherine C. Wong , Development of a fission yeast-based high throughput 2 1 John R. Yates 3rd , David G. Drubin . 1) Molecular and screen to target heterologously-expressed cAMP Cell Biology, University of California-Berkeley, Berkeley, signaling pathway proteins. Ana Santos de Medeiros, CA; 2) Department of Chemical Physiology, The Scripps Alexander Magee, Grace Kwak, Sam Rivera, Jordan Research Institute, La Jolla, CA. Vanderhooft, Rachel Gottlieb, Charles S. Hoffman. Biology Dept, Boston College, Chestnut Hill, MA. 385A Elucidating the metabolic basis of cancer using yeast as 393C a surrogate system: A model for tumorigenesis. S. cerevisiae as a Platform for High Throughput 1 2 Jaswandi U. Dandekar , Abhay Kumar , P. Jayadeva Screening and Variant Analysis of the Sphingosine-1- 1 Bhat . 1) Department of Biosciences and Bioengineering, Phosphate Receptor Family. Jacob Hornick1, Son Indian Institute of Technology Bombay, Mumbai, India; 2) Nguyen4, Pam Benegal3, Shen-Shu Sung2, James Broach1. Thyrocare Technologies Limited, Navi Mumbai. 1) Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, 386B Hershey, PA; 2) Department of Pharmacology, Interactions of HEM25 with Genes Encoding for the Pennsylvania State University College of Medicine, Mitochondrial Transporters Family (SLC25). J. Noelia Hershey, PA; 3) Department of Molecular Biology, Dufay1, J. Pedro Fernández-Murray1, Christopher R. Princeton University, Princeton, NJ; 4) Union College, McMaster1,2. 1) Biochemistry & Molecular Biology, Schenectady, NY. Dalhousie University, Halifax, Nova Scotia, Canada; 2)
42
Poster Session Listings
394A Zahra NaghdiGheshlaghi, Jolanda van Leeuwen, Brenda Ribosomal Perturbation as a Strategy for Improving Andrews, Charles Boone. Donnelly Centre, University of Protein Biogenesis in Cystic Fibrosis. Mert Icyuz1, Toronto, Toronto, ON, Canada. Kathryn E. Oliver2, Eric J. Sorscher2, John L. Hartman IV1. 1) Genetics, University of Alabama at Birmingham, 402C BIRMINGHAM, AL; 2) Gregory Fleming James Cystic Genetic Analysis of the Warburg Effect in Yeast. Fibrosis Research Center, University of Alabama at Mobolanle Olayanju, James Hampsey, Michael Hampsey. Birmingham,BIRMINGHAM, AL. Department of Biochemistry and Molecular Biology, Rutgers University - R W Johnson Medical School, 395B Piscataway, NJ. Arg-Trp-Arg based peptidomimetics with antifungal activity. Camilla E. Larsen1, Camilla J. Larsen2, Henrik 2 1 403A Franzyk , Birgitte Regenberg . 1) Department of Biology, Discovering Novel Inhibitors of Deubiquitinases in vivo: University of Copenhagen , Copenhagen , Denmark; 2) Strategies using Budding Yeast. Natasha Pascoe1,2, Department of Drug Design and Pharmacology, Faculty of Michael Costanzo1,2, Sachdev Sidhu1,2,3, Charles Boone1,2,3. Health and Medical Sciences, University of Copenhagen, 1) Molecular Genetics, University of Toronto, Toronto, Denmark. Ontario, Canada; 2) Terrance Donnelly Center for Cellular and Biomolecular Research, University of Toronto, 396C Toronto, Ontario, Canada; 3) Banting and Best Department Expression, modification and characterization of fungal of Medical Research, University of Toronto, Toronto, natural products in Saccharomyces cerevisiae. C. Ontario, Canada. Harvey, J. Li, M. Hillenmeyer, R. Davis. Stanford Genome Technology Center, Stanford University, Stanford, CA. 404B A connection between chromosome 397A condensation/cohesion pathways and the toxic effects of Chemical genomic profiling in S. cerevisiae and S. the Huntington disease protein in a yeast model. pombe to functionally annotate large compound Biranchi N. Patra, Scott Breslow, Jocelyn Wensel, collections. Sheena C. Li1,4, Jeff Piotrowski2, Raamesh Animesh Ray. School of Applied Life Sciences, Keck Deshpande3, Scott Simpkins3, Justin Nelson3, Jacqueline Graduate Institute, Claremont, CA. Barber1, Minoru Yoshida1, Chad L. Myers3, Charles 1,4 Boone . 1) RIKEN CSRS, Wako, Saitama, Japan; 2) 405C GLBRC, University of Wisconsin-Madison; 3) University Anti amyloidogenic potential of danshen derived of Minnesota; 4) University of Toronto, Canada. chemicals and their analogs analysed by in vitro and in vivo yeast assay. Afsaneh Porzoor1, Lynne J. 398B Waddington2, Helmut Hügel3, Danilla Grando1, Ian G. Genome-wide screening in yeast identifies genes Macreadie1, Joanne M. Caine2. 1) Scool of Applied involved in the localization of human poly (ADP-ribose) Sciences- Biosciences, RMIT University, Melbourne- polymerase 1. Samuele Lodovichi1, Giulia Rocchi1, Bundoora, VIC, Australia; 2) 2Materials Science and Marco La Ferla1, Alberto Mercatanti1, Tiziana Cervelli1, Engineering, CSIRO Preventative Health Flagship, 343 Maria Adelaide Caligo2, Alvaro Galli1. 1) CNR, Pisa, Italy; Royal Parade, Parkville, Victoria 3052, Australia; 3) 2) Azienda ospedaliera Santa Chiara, Pisa, Italy. School of Applied Sciences, Applied Chemistry, RMIT University, Melbourne, Victoria 3000, Australia. 399C Shared pHenotypes: Using a yeast genetic screen as a 406A way to identify mammalian genes required for cellular A yeast synthetic genetic interaction screen predicts the survival during intracellular acidification. Jennifer A. importance of Plk1 for the viability of cancer cells over- McQueen, John Shin, Susan Li, Pamela Austin, Calvin expressing CKS1b. Robert J. D. Reid1, Xing Du2, Ivana Roskelley, Christopher Loewen. Cellular and Physiological Sunjevaric1, Vinayak Rayannavar2, John Dittmar1, Matt Sciences, Univ British Columbia, Vancouver, BR., BC, Maurer2, Rodney Rothstein1. 1) Genetics & Development, Canada. Columbia University Medical Center, New York, NY; 2) Dept of Medicine, Columbia University Medical Center, 400A New York, NY. The Effects of Omega-3-Fatty Acids on Intracellular inositol levels in Saccharomyces Cerevisiae. Marlene N. 407B Murray, Bomi Kim, Jee Yeon Lee. Biology, Andrews Efflux of the quinone methide maytenin through yeast University, Berrien Springs, MI. cell Saccharomyces cerevisiae model. T. M. Souza- Moreira1, V. A. F. F. M. Santos1, S. R. Valentini2, C. F. 2 1 401B Zanelli , M. Furlan . 1) Organic Chemistry, Institute of Making Genetic Suppressors for Yeast Genes Whose Chemistry, UNESP, Araraquara, Sao Paulo, Brazil; 2) Orthologs are Involved in Human Retinitis Pigmentosa.
43
Poster Session Listings
Biological Sciences, School of Pharmaceutical Sciences, 414C UNESP, Araraquara, SP, Brazil. Tyre: An in Silico Simulator of Population Dynamics. Jill N. Wright1, Jessica Stilwell2, Christopher Zahner1, Hui 1 1 408C Hua , Brandt L. Schneider . 1) Cell Biology and Small molecule inhibitors of human Tsg101. Katherine Biochemistry, Texas Tech University Health Sciences A. Strynatka, Pak P. Poon, Christopher R. McMaster. Center, Lubbock, TX; 2) Texas Tech University, Howard Dalhousie University, Halifax, Canada. Hughes Medical Institute, Lubbock, TX.
409A 415A Developing assays for pathogenic human variation via Balony: a software package for analysis of data systematic testing of yeast/human complementation. generated by synthetic genetic array experiments. Song Sun1,2,3,4,5, Fan Yang1,2,3,4, Guihong Tan1,2, Michael Barry Young, Christopher Loewen. Dept Cell Phys Sci, Costanzo1,2, Rose Oughtred6, Jodi Hirschman6, Chandra Life Sci Inst, Vancouver, BC, Canada. Theesfeld6, Analyn Yu1,2,3,4, Tanya Tyagi1,2,3,4, Brenda Andrews1,2, Nidhi Sahni7,8, Song Yi7,8, David Hill7,8, Marc Vidal7,8, Charlie Boone1,2, Kara Dolinski6, Frederick Global Analysis: Networks Roth1,2,3,4,7. 1) Donnelly Centre, University of Toronto, Toronto, Ontario, Canada; 2) Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; 3) Department of Computer Science, University of Toronto, Toronto, Ontario, Canada; 4) Lunenfeld- 416B Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, Profiling the RNA maturation landscape in yeast. Ontario, Canada; 5) Department of Medical Biochemistry Alexander Ratushny1,2, Marlene Oeffinger4, Wei-Ming and Microbiology, Uppsala University, Uppsala, Sweden; Chen2, Karen Wei4, Peter Fridy3, Richard Rogers2, Ramsey 6) Lewis-Sigler Institute for Integrative Genomics, Saleem1,2, Garrett Poshusta1, Michael Rout3, John Princeton University, Princeton, New Jersey, USA; 7) Aitchison1,2. 1) Systems Biology, Institute for Systems Center for Cancer Systems Biology (CCSB), Dana-Farber Biology, Seattle, WA, USA; 2) Seattle Biomedical Cancer Institute, Boston, MA, USA; 8) Department of Research Institute, Seattle, WA, USA; 3) Rockefeller Genetics, Harvard Medical School, Boston, MA, USA. University, New York, NY, USA; 4) Institut de recherches cliniques de Montréal, Montréal, Québec, Canada. 410B Exploiting cancer-specific metabolism as a therapeutic 417C strategy. L. H. Wong, G. Giaver, C. Nislow. Cin5, Gln3, Hmo1, and Zap1 Contribute to the Gene Pharmaceutical Sciences, University of British Columbia, Regulatory Network Controlling the Cold Shock Vancouver, BC, Canada. Response in Saccharomyces cerevisiae. Kam D. Dahlquist1, Ben G. Fitzpatrick2, Cybele Arsan1, Wesley T. 1 1 1 Citti , Kevin C. Entzminger , Andrew F. Herman , Lauren N. Kubeck1, Stephanie D. Kuelbs2, Heather King1, Global Analysis: Elizabeth M. Liu1, Matthew Mejia1, Kenny R. Rodriguez1, Informatics/Computational Biology Nicholas A. Rohacz1, Olivia S. Sakhon1, Katrina Sherbina2, Alondra J. Vega2. 1) Biol, Loyola Marymount Univ, Los Angeles, CA; 2) Math, Loyola Marymount Univ, Los Angeles, CA.
411C 418A Transcriptional regulation and protein complexes in Dissecting the Regulation of the Yeast Pleiotropic Drug budding yeast. Stacia R. Engel, Maria C. Costanzo, Response. Colin Harvey, Ulrich Schlecht, Sundari Suresh, Kelley Paskov, J. Michael Cherry. Dept Genetics, Stanford Robert St. Onge, Ronald Davis, Maureen Hillenmeyer. Univ, Stanford, CA. Stanford Genome Technology Center, Stanford University, Palo Alto, CA. 412A TreeView 3.0: Visualization and Analysis of Two- 419B Dimensional Genomic Data. Christopher Keil, Anastasia Transferability of protein-protein interactions and Baryshnikova. Lewis-Sigler Institute for Integrative protein function between closely related species. Hsueh- Genomics, Princeton University, Princeton, NJ. lui Ho1, Maxime Huvet2, Michael Stumpf2, Ken Haynes1. 1) Biosciences, 3rd floor Geoffrey Pope Building, Exeter 413B University, Exeter, Devon, EX4 4QD United Kingdom; 2) WITHDRAWN Theoretical System Biology, Imperial College London, London, United Kingdom.
44
Poster Session Listings
420C 426C Measuring changes in genetic interactions over TheCellMap.org: storing and visualizing genetic environments using iSeq. Mia Jaffe1, Gavin Sherlock1, interactions in S. cerevisiae. Matej Usaj1, Michael Sasha F. Levy2. 1) Dept of Genetics, Stanford University, Costanzo1, Chad L. Myers2, Brenda Andrews1, Charles Stanford, CA; 2) Laufer Center for Physical and Boone1, Anastasia Baryshnikova3. 1) Donnelly CCBR, Quantitative Biology, Stony Brook University, Stony University of Toronto, Toronto, Ontario, Canada; 2) Brook, NY. Department of Computer Science and Engineering, University of Minnesota, Minneapolis, MN, USA; 3) 421A Lewis-Sigler Institute for Integrative Genomics, Princeton Extensive inbound and feedback signal integration by University, Princeton, NJ, USA. Protein Kinase A. Christian Landry1, Marie Filteau1, Guillaume Diss1, Francisco Torres-Quiroz1, Alexandre 427A Dube1, Isabelle Gagnon-Arsenault1, Andree-Eve Chretien1, Unraveling protein network evolution through whole- Ugo Dionne2, Anne-Lise Steunou2, Andrea Schraffl3, proteome cross-species interactome mapping. Haiyuan Jacques Cote2, Nicolas Bisson2, Eduard Stefan3. 1) Yu. Biological Statistics and Computational Biology, Département de Biologie, PROTEO and Institut de Cornell University, Ithaca, NY. Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Québec, G1V 0A6, Canada; 2) Département de Biologie Moléculaire, Biochimie Médicale et Pathologie, et Centre de Recherche sur le Cancer, Global Analysis: Other Yeasts Université Laval, Québec, Québec, G1V 0A6, Canada; 3) University of Innsbruck, Institute of Biochemistry and Center for Molecular Biosciences Innsbruck (CMBI), A- 6020 Innsbruck, Austria. 428B Functional Characterisation of Candida glabrata Open 422B Reading Frames with no Orthologue in Saccharomyces Genome-scale analyses of Saccharomyces cerevisiae cerevisiae. Lauren C. Ames1, Jane Usher1, Ilias strains evolved for bio-ethanol production under Kounatidis2, Petros Ligoxygakis2, Ken Haynes1. 1) aerobic and anaerobic growth conditions. Kevin S. Biosciences, University of Exeter, United Kingdom; 2) Myers1,2, Nicholas M. Riley3,4, Trey K. Sato2, Joshua J. Department of Biochemistry, University of Oxford, UK. Coon3,4,5, Audrey P. Gasch1,2. 1) Laboratory of Genetics, UW-Madison, Madison, WI; 2) Great Lakes Bioenergy 429C Research Center, UW-Madison, Madison, WI; 3) Comparative genomics and transcriptomics of the Department of Chemistry, UW-Madison, Madison, WI; 4) industrial yeast species Dekkera (Brettanomyces) Genome Center, UW-Madison, Madison, WI; 5) bruxellensis. Anthony Borneman1, Lucy Joseph2, Toni Department of Biomolecular Chemistry, UW-Madison, Cordente1, Robyn Kievit1, Ryan Zeppel1, Warren Albertin3, Madison, WI. Isabelle Masneuf-Pomarede3, Linda Bisson2, Chris Curtin1. 1) Australian Wine Research Institute, Urrbrae, 423C SA 5064, South Australia, Australia; 2) Department of A gene network model of cellular aging and its Viticulture and Enology, University of California, Davis, applications. Hong Qin. Biology, Spelman College, 595 Hilgard Lane, Davis, CA 95616; 3) Univ. de Bordeaux, Atlanta, GA. ISVV, EA 4577, Unité de recherche Œnologie, F-33140 Villenave 13 d'Ornon, France. 424A Genetic pathways involved in response to the phenol- based compounds bisphenol-A (BPA), butylated hydroxyanisole (BHA), and butylated hydroxytoluene 1 430A (BHT) in Saccharomyces cerevisiae. Shravya L. Raju , Assembling the Schizosaccharomyces kambucha genome Julia Levy2, Elizabeth Martin3, Mia Pecora1, Gretchen 1,2,3 and the dynamic transposon landscape of fission yeasts. Edwalds-Gilbert . 1) Scripps College, Claremont, CA; 2) Michael Eickbush1, Sarah Zanders1, Gerry Smith1, Harmit Pitzer College, Claremont, CA; 3) Claremont McKenna Malik1,2. 1) Basic Sciences, Fred Hutchinson Cancer College, Claremont, CA. Research Center, Seattle, WA; 2) Howard Hughes Medical Research Institution, Chevy Chase, MD. 425B Widespread changes in the yeast protein interaction 431B network in response to diverse environmental cues. U. Evolutionary genomics of ecological speciation in Schlecht1, J. Smith1, A. Celaj2, S. Suresh1, M. Miranda1, R. 1 2 1 Saccharomyces paradoxus. Jean-Baptiste Leducq, Lou W. Davis , F. Roth , R. P. St.Onge . 1) Biochemistry, Nielly-Thibaut, Guillaume Charron, Christian Landry. Stanford University, Palo Alto, CA; 2) Donnelly Centre, Département de Biologie, Université Laval, Quebec, QC, University of Toronto, Toronto, Ontario. Canada.
45
Poster Session Listings
432C Kirrmaier1, Michael Costanzo3, Charles Boone3, Wolfgang Comparative Genomics of Yeast Genome Conformation Huber2, Michael Knop1. 1) Center for Molecular Biology of and Functional Annotation by Multiplexed Hi-C. Ivan the University of Heidelberg (ZMBH), DKFZ-ZMBH Liachko, Joshua Burton, Jay Shendure, Maitreya Dunham. Alliance, Heidelberg, Germany; 2) European Molecular Genome Sciences, University of Washington, Seattle, WA. Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany; 3) Banting and Best Department of 433A Medical Research and Department of Molecular Genetics, Identifying biological pathway targets for lipid The Donnelly Centre, University of Toronto, Toronto, production in Yarrowia lipolytica. Kyle R. Pomraning, Ontario, Canada. Siwei Wei, Sue A. Karagiosis, Young-Mo Kim, Alice Dohnalkova, Mary S. Lipton, Galya Orr, Thomas O. Metz, 439A Scott E. Baker. Pacific Northwest National Lab, Richland, Stable-seq: High-throughput Analysis of in vivo Protein WA. Stability. Ikjin Kim1, Christina Miller1,2, Stanley Fields1,2,3. 1) Department of Genome Sciences, University 434B of Washington, Seattle, WA, USA; 2) Howard Hughes Influence of the nitrogen source on the production of Medical Institute, University of Washington, Seattle, WA, volatile aroma compounds by non-conventional USA; 3) Department of Medicine, University of Saccharomyces species. Jiri Stribny, Roberto Pérez- Washington, Seattle, WA, USA. Torrado, Amparo Querol. Food Biotechnology, Institute of Agrochemistry and Food Technology, Paterna (Valencia), 440B Valencia, Spain. Proteomic analysis and metabolic exploration of Yarrowia lipolytica under different culture conditions. J. Shi, W. Chen. Nanyang Technological University, Global Analysis: Proteomics Singapore. 441C Identifying global changes in protein acetylation following heat shock. Rebecca E. Sides, Jeffrey A. Lewis. 435C Biological Sciences, University of Arkansas, Fayetteville, Evaluating Common Humoral Responses Against AR. Fungal Infections With Yeast Protein Microarrays. Paulo Coelho1,2, Hogune Im3, Karl Clemons1,2, Michael 3 1,2 442A Snyder , David Stevens . 1) Dept of Medicine, Stanford Identification of long-lived proteins in cells undergoing University, Palo Alto, CA; 2) Calif. Inst. Med. Res., San repeated asymmetric divisions. NH Thayer1,2,3, C. Jose, CA; 3) Dept of Genetics, Stanford University, Palo Leverich1,3, E. Marsh1, M. Fitzgibbon1, ZW Nelson1, KA Alto, CA. Henderson1, J. Hsu1, DE Gottschling1. 1) Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA; 2) 436A Molecular and Cellular Biology Program, University of The caveolin-binding motif of the pathogen-related Washington, Seattle, WA; 3) These authors contributed yeast protein Pry1, a member of the CAP protein equally to this work. superfamily, is required for in vivo export of cholesteryl 1 1 acetate. Rabih Darwiche , Vineet Choudhary , David 443B Gfeller2, Olivier Michielin2, Vincent Zoet2, Roger 1 A systematic investigation of small metabolite Schneiter . 1) Division of Biochemistry, Department of interactions with regulatory proteins in yeast. G. X. Biology, University of Fribourg , 1700 Fribourg, Yang, X. Li, M. Bruno, M. Snyder. Department of Switzerland; 2) Molecular Modeling, Swiss Institute of Genetics, Stanford University, Stanford, CA. Bioinformatics , Quartier Sorge, Batiment Genopode, 1015 Lausanne, Switzerland.
437B Global Analysis: Technology Phosphoproteome analysis of the DNA damage response during S phase in Saccharomyces cerevisiae. Dongqing Huang, Brian Piening, Corey Weinert, Amanda Paulovich. Clinical Division, Fred Hutchinson Cancer Research, 444C Seattle, WA. Measuring stress response in Saccharomyces cervisiae using Isotopic Ratio Outlier Analysis (IROA) for 438C metabolome-wide quantitation. Felice A. de Jong, Chris Functional profiling of the ubiquitin-proteasome system Beecher. IROA Technologies LLC, Ann Arbor MI. of protein degradation. Anton Khmelinskii1, Bernd Fischer2, Joseph D. Barry2, Matthias Meurer1, Daniel
46
Poster Session Listings
445A Genome Technology Center, Stanford University, Palo 50:50 and IpO: Two new PCR-based methods for Alto, CA; 3) Genome Biology Unit, European Molecular marker-free, seamless genome modification in yeast. Joe Biology Laboratory, Heidelberg, Germany. Horecka, Angela Chu, Davis Ronald. Biochemistry, Stanford University, Stanford, CA. Global Analysis: Other 446B Multiplex, marker-less genetic engineering in S. cerevisiae. Andrew Horwitz, Max Schubert, Jack Newman. Amyris, Emeryville, CA. 453C 447C Seeking a metabolic understanding of chronological Biosensors engineered from conditionally stabilized aging. Haley Albright, Crystal Maharrey, Daniel Smith, ligand-binding domains. Benjamin Jester1,2, Christine John L. Hartman IV. Department of Genetics, University of Tinberg3, Justin Feng4, Dan Mandell5, George Church5, Alabama at Birmingham, Birmingham, AL. David Baker1,3, Stanley Fields1,2,6. 1) Howard Hughes Medical Institute, University of Washington, Seattle, WA; 454A 2) Department of Genome Sciences, University of Systems biology guided engineering of reduced ethanol Washington, Seattle, WA; 3) Department of Biochemistry, production in industrial wine yeast. Anthony R. University of Washington, Seattle, WA; 4) Division of Borneman, Cristian Varela, Simon Schmidt, Paul J. Medical Sciences, Harvard Medical School, Boston, MA; Chambers, The Australian Wine Yeast Systems Biology 5) Department of Genetics, Harvard Medical School, Consortium. Wine Biosciences, The Australia Wine Boston, MA; 6) Department of Medicine, University of Research Institute, South Australia, Australia. Washington, Seattle, WA. 455B 448A Instant killing of yeast for protein studies during Acetylation of carotenoids in Yarrowia lipolytica continuous culture. Sara S. Dick, Khyla Rose Alorro, improves cell viability and titers. Lisa Laprade, Maria Sean McNabney. Biology, Valparaiso University, Mayorga, Chris Farrell, Peter Houston, Dan Grenfell-Lee, Valparaiso, IN. Joshua Trueheart. DSM Microbia, Lexington, MA. 456C 449B Uncovering the biophysical impact of sequence Phenomic Analysis of TOR Signaling and dNTP variation. Kathryn M. Hart, Jasper Rine. University of Metabolism. Sean M. Santos, Chandler Stisher, Darryl California Berkeley, Berkeley, CA. Outlaw, Jingyu Guo, John L. Hartman, IV. Department of Genetics, University of Alabama at Birmingham, 457A Birmingham, AL. Reverse Two Hybrid, a systematic approach for identifying genes and pathways that regulate a specific 450C protein- protein interaction. Ifat Lev, Marina Volpe, An automated system for time-lapse imaging of Shay Bev Aroya. Faculty of Life Sciences, Bar-Ilan microbial biofilms. Adrian Scott, Aimée M. Dudley. University, Ramat-Gan, Israel. Pacific Northwest Diabetes Research Institute, Seattle, WA.
451A 458B Development of ODELAY, a scalable, automated, Profiling of Saccharomyces yeast populations in two multiparameter growth rate analysis platform, and British Columbia vineyards and wineries. J. Martiniuk, application to a yeast model of Parkinson’s disease. 1 1,2 V. Measday. Wine Research Centre, University of British David J. Dilworth , Alexander V. Ratushny , Thurston E. Columbia, Vancouver, BC, Canada. Herricks1, Jennifer J. Smith1, Song Li1, John D. Aitchison1,2. 1) Institute for Systems Biology, Seattle, WA; 2) Seattle Biomedical Research Institute, Seattle, WA. 459C Staying current and modern: Overhauling an actively- used model organism database website. Kelley M. 452B Paskov, Stacia R. Engel, Gail Binkley, J. Michael Cherry. Genome Wide Manipulation of Transcription in Department of Genetics, Stanford University, Stanford, Saccharomyces cerevisiae using CRISPR-Cas9 CA. Transcription Factors. Justin D. Smith1,2, Ulrich Schlecht2, Sundari Suresh2, Ron W. Davis2, Leopold Parts3, Robert P. St. Onge2. 1) Department of Genetics, Stanford University School of Medicine, Stanford, CA; 2) Stanford
47
Poster Session Listings
460A NOTES Underlying the phenotypic contribution of a single quantitative trait locus in yeast are effects of seven genes and their epistatic interactions. R. Shapira, T. Benbenishty, L. David. ANIMAL SCIENCES, FACULTY OF AGRICULTURE, FOOD AND ENVIRONMENTAL QUALITY SCIENCES, THE HEBREW UNIVERSITY OF JERUSALEM, ISRAEL, REHOVOT, ISRAEL.
461B Stability and Patterning in Microbial Communities: Lessons from Engineered Yeast Populations and Mathematical Modeling. Wenying Shou1, Babak Momeni1, Kristine Brileya2, Matthew Fields2. 1) Fred Hutchinson Cancer Research Center, Seattle, WA; 2) Montana State University, Bozeman, MT.
462C Regulation of biofilm development through the simultaneous activation and repression of functionally distinct extracellular proteins. Zhihao Tan1,2, Michelle Hays1, Cecilia Garmendia-Torres3, Gareth A. Cromie2, Amy Sirr2, Eric W. Jeffery2, Patrick May4, Aimée M. Dudley1,2. 1) Molecular and Cellular Biology Program, University of Washington, Seattle, WA; 2) Pacific Northwest Diabetes Research Institute, Seattle; 3) Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France; 4) Luxembourg Center for Systems Biomedicine, University of Luxembourg, Luxembourg.
Academic Teaching
463A Interdisciplinary research on anticancer ruthenium complexes links undergraduate courses and improves student learning and confidence. Pamela Hanson1, Laura Stultz2. 1) Biology Department, Birmingham-Southern College, Birmingham, AL; 2) Chemistry Department, Birmingham-Southern College, Birmingham, AL.
464B The 15-week PhD: research methods training for MS Biotechnology students through laboratory investigations of yeast cell physiology. Robert M. Seiser. Biological, Chemical and Physical Sciences, Roosevelt Univ, Schaumburg, IL.
465C WITHDRAWN
48
Speaker and Author Index This index includes names in alphabetical order of all invited authors, and co-authors published in this book. The number following a name refers to the abstract’s program number. An asterisk denotes a presenting author. Platform Presentations: 1-69, Poster Presentations 70A-465C.
Ang, Sidney,...... 272B Bennett, Richard, ...... 335B Angela, Jacavone, ...... 60 Berman, J., ...... 363C Anrather, Dorothea, ...... 184A Berman, Judith, ...... 56 A Antipov, Eugene,...... 106A Berman, Judith G., ...... 270C* Abdel-Banat, Babiker M. A., .... 258C* Aoki, Hiroyuki, ...... 135C Berry, David, ...... 171C Abeliovich, H., ...... 133A Arens, Christina, ...... 326B Bertuch, Alison, ...... 263B Abeliovich, Hagai, ...... 153C Arndt, Karen, ...... 12 Bev Aroya, Shay,...... 457A Abeysinghe, Amali P., ...... 6 Arnone, James T., ...... 187A* Bharatula, Vasudha, ...... 294C* A. Cromie, Gareth, ...... 462C Arroyo-López, F. N., ...... 345C Bhat, P. Jayadeva,...... 385A Adamus, Paulina, ...... 246C Arsan, Cybele, ...... 417C Bhatt, Kushal, ...... 316A Adhikari, Hema,...... 156C*, 157A* Arsenault, Heather, ...... 4 Bhattacharyya, Dibyendu, ...... 189C Aebersold, R., ...... 21 Asbury, Charles, ...... 33, 110B Bhave, Madhura D., ...... 189C* Aebersold, Ruedi, ...... 9 Asbury, Charles L., ...... 32 Bibi, Maayan, ...... 270C Agmon, Neta, ...... 381C* Asiago, Josephat,...... 147C Bigey, Frédéric, ...... 295A Aharoni, Amir, ...... 259A* Aslam, Kiran, ...... 147C Biggins, Sue, ...... 31, 33, 109A, Ahler, Ethan, ...... 382A* Åström, Stefan U.,...... 268A ...... 223A, 224B Ahn, Hyo Won, ...... 265A* Athanasiadou, Rodoniki, ...... 289A Binkley, Gail, ...... 459C Aindow, Ann, ...... 141C Attanasio, Nicholas, ...... 306C Bisson, Linda, ...... 429C Airoldi, Edo, ...... 77B Augustine, Andrew, ...... 141C Bisson, Nicolas, ...... 421A Aitchison, John, ...... 416B* Augustine, Beryl, ...... 70A* Bjorklund, Stephan, ...... 294C Aitchison, John D., ...... 451A Austin, Pamela, ...... 399C Blaszak, Scott, ...... 166A Aiyar, Raeka, ...... 299B, 368B Australian Wine Yeast Systems Blum, A., ...... 19 Akada, R., ...... 118A Biology Consortium, ...... 454A Boada, Jordi, ...... 163A Akada, Rinji, ...... 258C Ayala, G., ...... 291C Bodenmiller, Bernd, ...... 9 Akao, Takeshi, ...... 105C Boeke, J. D., ...... 208A Akey, Joshua, ...... 274A B Boeke, Jef, ...... 313A, 381C Akey, Joshua M., ...... 47 Babu, Mohan, ...... 135C, 145A Boettcher, Adeline, ...... 166A Alam, Md Maksudal, ...... 205A Babu, Sabareesh, ...... 309C Bojsen, Rasmus, ...... 379A Alam, Nashida, ...... 1 Bailey, Melanie, ...... 69 Boldrin, PPaulo E. G., ...... 197B Albert, Frank W., ...... 26* Bakalinsky, A., ...... 133A Bonarigo, Elizabeth, ...... 134B Albertin, Warren, ...... 429C Baker, David, ...... 447C Bontron, Séverine, ...... 173B Albright, Haley, ...... 453C* Baker, Scott E., ...... 433A Boone, C., ...... 79A, 138C, 362B Alexander, Margaret, ...... 257B Bandmann, Konstanze,...... 181A Boone, Charles, ...... 18, 38, 39, 57, Alexander, William, ...... 349A Banning, Ryan, ...... 276C ...... 369C, 371B, 372C, 378C, 397A, Alexander, William G., ...... 24 Bansal, Paul,...... 38 ...... 401B, 403A, 409A, 426C, 438C Allison, Mary, ...... 277A Barber, Jacqueline, ...... 372C, 397A Booth, Elizabeth, ...... 52 Alonso-Perez, E., ...... 331A* Barboas, Natalia M., ...... 197B Borden, MA, ...... 138C Alorro, Khyla Rose, ...... 455B Barrajón Simancas, N.,...... 102C Borneman, Anthony, ...... 429C Altelaar, Maarten, ...... 11 Barrey, Evelyne, ...... 178A Borneman, Anthony R., ...... 454A* Altintas, Dogus, ...... 378C Barrio, E., ...... 345C Botstein, D., ...... 78C Alvarado, Melanie, ...... 254B Barry, Joseph D., ...... 438C Botstein, David, ...... 27, 242B Alvaro, Christopher, ...... 141C* Baryshnikova, Anastasia, ...... 18, 38, Boucherle, Marine, ...... 277A Ames, Lauren C., ...... 428B* 39, 356B*, 412A, 426C Bougnoux, Marie-Elisabeth, ...... 358A Ammerer, Gustav, ...... 184A, 293B* Bauer, Florian F., ...... 211A Bower, Jean, ...... 257B Amon, Angelika, ...... 113B Beas, Anthony O., ...... 188B* Brace, J., ...... 76A Anders, Kirk, ...... 273C Becker, B.,...... 19* Brace, Jennifer L., ...... 72C* Anders, Simon, ...... 368B Becker-Kettern, Julia,...... 71B* Bradford, Dan, ...... 17 Andersen, Kaj S., ...... 379A Beecher, Chris, ...... 444C Bradford, S., ...... 133A Anderson, Carol, ...... 28* Begany, Marketa, ...... 104B Brandão, Luis, ...... 244A Ando, Hiromi, ...... 254B Beh, Christopher T., ...... 200B Brar, Gloria,...... 131B Andre, B.,...... 142A* Bekiranov, Stefan, ...... 217A Breeden, Linda L., ...... 6* André, Bruno, ...... 152B Belton, Jon-Matthew, ...... 376A Brem, Rachel B., ...... 150C Andrews, B. J., ...... 79A Benanti, Jennifer, ...... 4* Brent, R., ...... 158B Andrews, Brenda, ...... 38, 39, Ben-Aroya, S., ...... 143B* Breslow, Scott, ...... 404B ...... 57, 197B, 369C, 371B, Ben A. roya, Shay, ...... 194B Bretner, Maria, ...... 247A ...... 378C, 401B, 409A, 426C Benbenishty, T., ...... 460A Brewer, Bonny, ...... 262A Andrie, Jennifer M., ...... 47* Bendrioua, Loubna, ...... 179B Brewer, J., ...... 53 Andrykovich, Kristin, ...... 257B Benegal, Pam, ...... 393C Briggs, Meredith, ...... 191B Ang, Jonathan S., ...... 231C* Bennett, Eric J., ...... 95B Brileya, Kristine, ...... 461B
49
Speaker and Author Index This index includes names in alphabetical order of all invited authors, and co-authors published in this book. The number following a name refers to the abstract’s program number. An asterisk denotes a presenting author. Platform Presentations: 1-69, Poster Presentations 70A-465C.
Brion, Christian,...... 311B Chen, Jingxun, ...... 113B* Cowen, Leah,...... 168C Britain, D., ...... 158B* Chen, Qihe, ...... 75C Cowen, Leah E., ...... 183C Broach, James, ...... 294C, 393C Chen, Rey-Huei, ...... 144C Crapeau, M., ...... 142A Broach, James R., ...... 286A, 376A Chen, W., ...... 440B Craven, Mark, ...... 7 Brodsky, Jeff, ...... 141C Chen, Wei-Ming,...... 416B Cromie, Gareth, ...... 127A, 297C*, Brown, Grant W.,...... 41, 378C Chen, Yiqun, ...... 57 ...... 363C, 370A Brown, G. W., ...... 362B Cheng, S., ...... 114C* Cucinotta, Christine, ...... 12* Brown, Joshua A. R., ...... 232A* Cheng, You-Liang, ...... 144C* Cui, Ping, ...... 309C Brozda, Izabela, ...... 246C, 247A Chereji, Razvan, ...... 294C Cullen, Paul, ...... 156C, 157A, 161B Brule, Christina, ...... 321C Cherry, J. Michael, ...... 318C, 387C, Cullen, Paul J., ...... 159C Bruno, M., ...... 443B ...... 411C, 459C Cuomo, Christina,...... 335B Bryan, Debra Sue, ...... 260B* Cheung, Stephanie, ...... 266B Cuperus, Josh, ...... 357C* Bryant, Eric, ...... 383B* Chew, Yuanyuan, ...... 192C Cuperus, Josh T., ...... 333C Bubnová, Michala, ...... 190A* Chiang, Mengying, ...... 307A Curtin, Chris, ...... 429C* Bucker, A., ...... 103A Chin, Cheen Fei,...... 74B*, 192C* Cvijovic, Marija, ...... 326B Budnik, Bogdan, ...... 77B Chiruvella, Kishore K., ...... 268A Cyert, Martha, ...... 9, 141C, 164B Burgess, Sean, ...... 251B Cho, Christina, ...... 52 Burston, Helen E., ...... 155B Choudhary, Vineet, ...... 436A D Burton, Joshua, ...... 432C Chow, Jacky, ...... 157A, 161B Dahl, Robert, ...... 301A Bush, Chad,...... 307A Chowdhary, Surabhi, ...... 296B* Dahlquist, Kam D., ...... 417C* Byeon, Boseon, ...... 14 Chretien, Andree-Eve, ...... 421A Dailey, Kaitlin M., ...... 233B*, 250A Byers, James, ...... 43 Christian, Nils, ...... 364A Dalton, Lauren E., ...... 145A* Chruscicki, Adam,...... 51, 218B Dandekar, Jaswandi U., ...... 385A* C Chu, Angela, ...... 445A Daran, JM., ...... 102C Caccamise, Lauren M., ...... 159C* Chu, Daniel, ...... 251B* Daran-Lapujade, P., ...... 102C Cai, Jin, ...... 75C Church, George, ...... 447C Dario, M. G., ...... 103A Caine, Joanne M., ...... 405C Ciccaglione, Kerri, ...... 283A Darwiche, Rabih, ...... 436A* Caligo, Maria Adelaide, ...... 398B Cinquin, Bertrand P., ...... 16 Darzacq, Xavier, ...... 29 Camera, Diawoye, ...... 161B Citti, Wesley T., ...... 417C Das, Asim Bikas, ...... 14 Cao, Thai, ...... 193A, 205A Civegna, Agnes, ...... 236B Dasika, Madhukar, ...... 106A Cap, Michal, ...... 73A*, 91A Clark, Nathan, ...... 123C, 332B* da-Silva, Wagner S., ...... 86B Capaldi, Andrew, ...... 160A* Clark, Nathan L., ...... 146B Datta, Kaustuv, ...... 132C*, 137B Capp, Jean-Pascal, ...... 295A* Clemons, Karl, ...... 435C Daum, Chris, ...... 375C Capps, Denise, ...... 307A Cloutier, Angeline, ...... 82A Dauster, Emma, ...... 16, 115A Cardenas, Maria E., ...... 167B Cluader-Münster, Sandra, ...... 299B David, L., ...... 460A Carroll, Sarah, ...... 154A Coelho, Paulo, ...... 435C* David Kadoch, Galit, ...... 194B Cattin-Ortolá, Jérôme,...... 110B Cohen-Fix, O, ...... 16, 115A*, 187A Davies, Danielle L., ...... 341B Caudy, Amy, ...... 13, 62, 88A, 107B Comer, Jonathan M., ...... 193A* Davis, Matthew, ...... 413B Caudy, Amy A., ...... 80B Conibear, E, ...... 145A, 149B, 155B Davis, R., ...... 396C Celaj, A., ...... 425B Connelly, Caitlin, ...... 274A* Davis, Ronald, ...... 418A Cervelli, Tiziana, ...... 398B Conrad-Webb, Heather, ...... 316A Davis, Ron W., ...... 452B Chakrabortee, Sohini, ...... 43 Cooley, B., ...... 133A Davis, R. W., ...... 425B Chambers, Paul J., ...... 454A Coon, Josh, ...... 171C Davis, Trisha, ...... 108C, 110B, 112A Chan, A., ...... 271A* Coon, Joshua, ...... 7 Davis, Trisha N., ...... 32 Chan, Leslie J., ...... 191B* Coon, Joshua J., ...... 422B De, Subho, ...... 55 Chan, Y., ...... 241A Cooper, Katrina F., ...... 36, 162C* de Graaf, Erik, ...... 11 Chang, T., ...... 292A Cooper, Terrance G., ...... 175A Dehé, Pierre-Marie, ...... 253A Chang, Yi-Shun, ...... 139A Cooper, T. G., ...... 298A Deineko, Viktor, ...... 145A Chao, Jesse T., ...... 51*, 218B Corbett, Kevin, ...... 33 de Jong, Felice A., ...... 444C* Chao, Lily, ...... 106A Cordente, Toni, ...... 429C Dekker, Job,...... 376A Chappell, Thomas, ...... 237C Cortesio, Christa L., ...... 384C* de la Torre-Ruiz, M A, ...... 163A* Charron, Guillaume, ...... 431B Corzilius, Björn, ...... 60 de Lima Alves, Flavia,...... 33 Chartrand, Pascal, ...... 263B Costanzo, M., ...... 362B de Medeiros, Ana Santos, ...... 392B Chasman, Deborah, ...... 7 Costanzo, Maria C., ...... 411C Demeter, Janos, ...... 318C Chaudhuri, Payel,...... 226A Costanzo, Michael, ...... 18, 38, 39, d'Enfert, Christophe, ...... 358A* Chauhan, Neha, ...... 2 ...... 57, 403A, 409A, 426C, 438C Deng, Yi, ...... 33 Chavel, Colin A., ...... 159C, 161B* Cote, Jacques, ...... 421A Dennis, Brandy A., ...... 195C Chen, Chichun, ...... 337A Cottier, Stéphanie, ...... 173B Dequin, Sylvie, ...... 295A Chen, J., ...... 78C Cournac, Axel, ...... 59 Deshpande, Raamensh, ...... 372C
50
Speaker and Author Index This index includes names in alphabetical order of all invited authors, and co-authors published in this book. The number following a name refers to the abstract’s program number. An asterisk denotes a presenting author. Platform Presentations: 1-69, Poster Presentations 70A-465C.
Deshpande, Raamesh, ...... 57, 397A Ehrenreich, Ian, ...... 22* Franke, Gary, ...... 134B Deshpande, Shweta, ...... 375C Eickbush, Michael, ...... 58, 430A* Frank Searle, Naomi E., ...... 280A* De-Souza, Evandro A., ...... 86B Elfving, Nils, ...... 294C Franzyk, Henrik, ...... 395B Deutschbauer, Adam, ...... 368B Elias, Joshua, ...... 164B Frederick, Kendra K., ...... 60* De Virgilio, Claudio, ...... 173B Ellahi, Aisha, ...... 275B*, 334A* Freidrich, Anne, ...... 340A de Visser, J. A G. M.,...... 350B, 351C Elston, Timothy, ...... 49 Freudenreich, Catherine H., ...... 249C DeWerff, Samantha J., ...... 166A Eltschinger, S., ...... 21 Frey, B. J., ...... 79A De Wulf, Peter, ...... 221B Emmerstorfer, Anita, ...... 325A* Frey, Brendan, ...... 378C Deyter, Gary M., ...... 31* Emuna, Lilach, ...... 194B* Fridy, Peter, ...... 416B Dick, Sara S., ...... 455B* Ene, Iuliana, ...... 335B* Friedrich, Anne, ...... 353B Dilworth, David J., ...... 451A Eng, Thomas, ...... 227B Friesen, H., ...... 79A Ding, J., ...... 133A* Engel, Stacia R., ...... 411C*, 459C Fritsch, Emilie, ...... 368B Dion, Mike, ...... 77B Entzminger, Kevin C., ...... 417C Frost, Adam, ...... 20 Dion, Vincent, ...... 249C Erdman, Scott, ...... 134B* Fukuda, Yusuke, ...... 50 Dionne, Ugo, ...... 421A Erinne, Olivia, ...... 309C Fukusaki, Eiichiro, ...... 209B Diss, Guillaume, ...... 421A Erlanger, Bracha,...... 229A Fultz, Kourtney, ...... 147C Dittmar, John, ...... 383B, 406A Ermakova, Marina, ...... 29 Fung, Jennifer, ...... 28 Dodson, Anne, ...... 10* Estill, Molly S., ...... 319A Furlan, M., ...... 407B Doerfler, Matthew, ...... 72C Evans, Irene M., ...... 195C* Futia, Raymond A., ...... 336C* Doering, Drew T., ...... 24 do Espirito-Santo, J. C., ...... 103A F G Dohnalkova, Alice, ...... 433A Fang, Nancy, ...... 266B Gagneur, Julien, ...... 361A, 368B Dolinski, Kara, ...... 409A Fang, Nancy N., ...... 51, 218B Gagnon-Arsenault, Isabelle, ...... 421A Doncic, Andreas, ...... 3* Fang, Ruosi, ...... 75C Gaillard, Pierre-Henri, ...... 253A Dong, Yachen, ...... 75C* Farrall, Nicholas, ...... 20 Galas, David, ...... 368B Dornhoffer, James, ...... 277A Farrell, Chris, ...... 448A Gallagher, Jen, ...... 220A Dorninger, Petra, ...... 236B Feng, Justin, ...... 447C Gallgher, Jennifer, ...... 374B Dorrity, Michael W., ...... 333C* Ferguson, Rebecca, ...... 244A Galli, Alvaro, ...... 398B Dotts, Kathleen, ...... 300C Fernández-Murray, J. Pedro, ...... 386B Gallo, Julia Allison, ...... 220A* Dowell, Robin, ...... 55 Ferrari, Jessica, ...... 293B Galvao, Fabio C., ...... 197B* Downey, Michael, ...... 40 Ferreira, Zelia, ...... 332B Gamble, Caitlin E., ...... 321C* Drendel, Holli, ...... 147C Ferreira, Zelia A., ...... 146B* Gammie, Alison, ...... 65* Drubin, David G., ...... 384C Field, Colby,...... 370A Gammie, Alison E., ...... 234C* Drummond, D. Allan, ...... 77B Fields, Matthew, ...... 461B Ganesan, Savita, ...... 106A Du, Xing, ...... 406A Fields, Stanley, ...... 64, 99C, 321C, Garcia-Martinez, J., ...... 291C Dube, Alexandre, ...... 421A 333C, 344B, 357C, 439A, 447C García-Martinez, Jose, ...... 373A Dubois, E., ...... 298A Filteau, Marie, ...... 421A García-Ríos, Estéfani, ...... 359B* Dubots, Emmanuelle, ...... 173B Finke, Cody, ...... 257B Garcia-Salcedo, Raul, ...... 179B, 182B Dudley, Aimée M., ...... 127A, 297C Finnigan, Gregory C.,...... 52* Gardner, Jennifer, ...... 17 ...... 363C, 364A, 370A, 450C Fischer, Bernd, ...... 438C Gardner, Timothy, ...... 106A Dufay, J. Noelia, ...... 386B* Fischer, Gilles, ...... 61, 353B Garfinkel, David, ...... 54, 265A, Duffy, Caroline, ...... 20 Fitzgibbon, M., ...... 442A ...... 267C, 269B Duffy, Hilary, ...... 239B Fitzpatrick, Ben G., ...... 417C Garmendia, Cecilia, ...... 297C Duffy, Supipi, ...... 231C Fiumera, Anthony C., ...... 348C Garmendia-Torres, Cecilia, ...... 462C Duina, Andrea, ...... 276C, 277A Fiumera, H L., ...... 140B, 336C, 348C Garmendia Torres, Cecilia, ...... 370A Dujon, Bernard, ...... 255C Fletcher, Andrew, ...... 180C Garre, Elena, ...... 326B* Dumas, Kathleen J., ...... 150C Folkesson, Anders, ...... 379A Gasch, Audrey P., ...... 7, 171C, Dunham, Maitreya, ...... 25, 99C, Fong, Kimberly, ...... 108C* 330C, 360C*, 375C, 377B, 422B ...... 108C, 228C, 338B, 339C, Forche, A.,...... 363C Gasser, Susan M., ...... 249C ...... 346A, 356B, 367A, 432C Foster, Leonard J., ...... 51, 218B Gaubitz, C.,...... 21 Duro, Eris,...... 33 Founk, Karen, ...... 378C Geddis, Alyssa, ...... 82A Dwight, Selina S., ...... 387C* Fowler, Douglas, ...... 382A Geiler-Samerotte, Kerry A., ...... 23*, Dyer, Jayme, ...... 49 Fowler, Douglas M., ...... 388A, 389B ...... 77B* Fowler, Kyle R., ...... 252C* Georis, I., ...... 298A* E Fox, Jesse Michael, ...... 196A* German, Sabrina, ...... 37 Eastwood, Michael, ...... 116B* François, Jean-Marie, ...... 295A Gestaut, Daniel R., ...... 32 Edwalds-Gilbert, Gretchen, ...... 424A François, JM., ...... 93C, 94A Gfeller, David, ...... 436A Edwards, S., ...... 76A* Frandsen, Rasmus Ghaddar, Kassem,...... 152B Egriboz, Onur, ...... 300C John Normand, ...... 98B Ghospurkar, P L., ...... 235A*, 250A
51
Speaker and Author Index This index includes names in alphabetical order of all invited authors, and co-authors published in this book. The number following a name refers to the abstract’s program number. An asterisk denotes a presenting author. Platform Presentations: 1-69, Poster Presentations 70A-465C.
Giaver, G., ...... 410B Hanson, Pamela, ...... 391A*, 463A* Ho, Yi-Hsuan, ...... 7* Gibney, P., ...... 78C* Hao, Xinxin, ...... 326B Hochstrasser, Mark, ...... 151A Gies, Keegan, ...... 273C Harer, John, ...... 305B Hochwagen, Andreas, ...... 119B Gillet-Markowska, Alexandre, ...... 61* Haring, Stuart, ...... 250A Hoffman, Charles S., ...... 392B* Gladyshev, Vadim N.,...... 365B Haring, Stuart J., ...... 233B, 235A Hofmann, Analise K., ...... 198C* Go, Chris, ...... 62 Harper, Jennifer, ...... 277A Hohmann, Stefan, ...... 179B, 182B Gógl, Gergõ, ...... 1 Harris, Samantha T., ...... 238A Hollenstein, David, ...... 293B Goldman, Aaron, ...... 9, 141C Harrison, Benjamin, ...... 270C Holzwarth, G., ...... 133A Gonçalves, Paula, ...... 24, 349A Hart, Kathryn M., ...... 456C* Hong, S.-P., ...... 199A* Gonzalez, R., ...... 291C Hartman, John L., IV,...... 449B Honigberg, Saul M., ...... 117C* Goswami, Sudip, ...... 300C Hartman IV, John L., ...... 394A, 453C Hooda, Jagmohan, ...... 193A, 205A Gottlieb, Rachel, ...... 392B Harvey, C., ...... 396C Hood-DeGrenier, J K.,...... 82A* Gottschling, Dan, ...... 67* Harvey, Colin, ...... 418A* Hoopman, Michael, ...... 112A Gottschling, Daniel E., ...... 34, 188B Hashemi, Jordan, ...... 270C Hope, Elyse A., ...... 339C* Gottschling, DE, ...... 138C, 442A Hashimoto, Tatsu, ...... 77B Hopkins, Kelly, ...... 134B Graczyk, Beth, ...... 108C Hawkins, Kristy, ...... 106A Hopper, Anita, ...... 46, 288C Graf, Marco, ...... 378C Haye, Joanna E., ...... 234C Hopper, Anita K., ...... 285C Grando, Danilla,...... 405C Haynes, K., ...... 363C Hopper, James E., ...... 300C* Gray, Vanessa E., ...... 388A* Haynes, Ken, ...... 419B, 428B Horecka, Joe, ...... 445A* Grayhack, Elizabeth, ...... 321C Hays, M, ...... 297C, 370A, 462C Hornick, Jacob, ...... 393C* Green, Robin, ...... 337A* Hazan, R., ...... 143B Horwitz, Andrew, ...... 446B* Gregory, Brian K., ...... 287B* Hazbun, Tony, ...... 147C*, 221B* Hose, James, ...... 7, 330C, 360C Grencser, Akos A., ...... 150C He, H., ...... 199A Hoshida, H., ...... 118A* Grenfell-Lee, Dan, ...... 448A Heidenreich, Erich, ...... 236B* Hoshida, Hisashi, ...... 258C Gresham, David, ...... 289A* Heider, Margaret, ...... 20 Hou, Jing, ...... 340A* Griffin, Robert G., ...... 60 Hejlova, Marcela, ...... 91A Houston, Peter, ...... 448A Griset, Margaret L., ...... 389B* Henderson, KA, ...... 442A Howe, LeAnn J., ...... 51, 218B Gross, David, ...... 296B Henderson, Kiersten A., ...... 34* Howe, Martha M., ...... 175A Grovenstein, Evan, ...... 391A Herauf, Anna, ...... 250A Hsu, Hsiang-En, ...... 281B* Grys, B., ...... 79A* Herman, Andrew F., ...... 417C Hsu, J., ...... 442A Gu, Zhenglong, ...... 314B, 355A Herman, Paul, ...... 186C Hua, Hui, ...... 414C Guacci, Vincent, ...... 227B Herman, Paul K., ...... 5 Huang, Dongqing, ...... 437B* Guerrero, G. M., ...... 261C* Herr, Alan, ...... 237C* Huang, Linda, ...... 125B Guillamón, José Manuel, ...... 359B Herrero, Eva, ...... 222C* Huber, Alexandre, ...... 184A Guillet, Marie, ...... 55 Herricks, Thurston E., ...... 451A Huber, Wolfgang, ...... 438C Guiney, Evan, ...... 164B* Hesselbart, Ana, ...... 354C Hubmann, Maria, ...... 236B Gullingsrud, Justin, ...... 64 Hesselberth, Jay, ...... 260B, 290B Hügel, Helmut, ...... 405C Guo, Jingyu, ...... 449B Hetenyi, Csaba, ...... 1 Hughes, Adam L.,...... 34 Guo, Xiaoxian, ...... 355A Hickman, Mark, ...... 27 Hughes, AL, ...... 138C Guo, Xin, ...... 305B Hickman, Meleah A., ...... 56* Hughes, Robert E., ...... 150C Gupta, Ishaan, ...... 299B* Hieter, P., ...... 241A, 271A Hughes Hallett, James, ...... 160A Gupta, Mohan, ...... 50* Hieter, Phil, ...... 231C, 272B, 390C Hughson, Frederick M., ...... 18 Gupta, Saumya, ...... 361A* Hieter, Philip, ...... 248B Humphryes, Neil A., ...... 119B* Hieter, Philip A., ...... 69* Hung, P. S., ...... 362B* H Hildebrand, Erica Marie, ...... 223A* Hunsucker, Alexandra, ...... 391A Haase, Steven B., ...... 305B Hildreth, Jonathan, ...... 269B Hurto, Rebecca L., ...... 285C* Hackett, Sean, ...... 8* Hill, David,...... 409A Huvet, Maxime, ...... 419B Hahn, Ji-Sook, ...... 202A, 303C Hillenmeyer, M., ...... 396C Hwang, M., ...... 292A Hakhverdyan, Zhanna, ...... 20 Hillenmeyer, Maureen,...... 418A Hyppa, Randy W., ...... 253A* Halfmann, Randal, ...... 44* Hinnebusch, Alan G., ...... 320B Haller, Jasmine, ...... 277A Hirakawa, Matthew, ...... 335B I Hampsey, James, ...... 402C Hirata, Aiko,...... 105C Icyuz, Mert, ...... 394A* Hampsey, Michael, ...... 15*, 402C Hirschman, Jodi, ...... 409A Ii, Miki,...... 254B* Hampton, Randolph, ...... 154A Hittinger, Chris, ...... 342C, 349A Ii, Tatsuya, ...... 254B Hamza, Akil, ...... 390C* Hittinger, Chris Todd, ...... 24* Im, Hogune, ...... 374B, 435C Hanchard, Julia, ...... 62 Hitz, William, ...... 329B Iosue, Christine, ...... 306C Hanchard, Julia A., ...... 80B* Hlavacek, Otakar, ...... 81C* Iosue, Christine L., ...... 319A, 341B* Hans, Bharat, ...... 82A Ho, Hsueh-lui, ...... 419B* Iyer, Prasanna, ...... 189C Hanson, Noah A.,...... 338B* Ho, Krystina, ...... 266B Izeddin, Ignacio, ...... 29
52
Speaker and Author Index This index includes names in alphabetical order of all invited authors, and co-authors published in this book. The number following a name refers to the abstract’s program number. An asterisk denotes a presenting author. Platform Presentations: 1-69, Poster Presentations 70A-465C.
Kao, Cheng-Fu, ...... 281B Koshland, Douglas, ...... 227B J Kaplan, C., ...... 302B Koszul, Romain, ...... 59 Jackson, R., ...... 199A Kaplan, Craig, ...... 309C Kounatidis, Ilias, ...... 428B Jaffe, Mia, ...... 420C* Karagiosis, Sue A., ...... 433A Krammer, Eva-Maria, ...... 152B Jain, Bhawik, ...... 189C Karra, Kalpana, ...... 387C Kraus, O., ...... 79A James, Michael, ...... 134B Karunanithi, Sheelarani, ...... 161B Kraus, Oren, ...... 378C Janke, Ryan, ...... 10, 282C* Karuppasamy, M., ...... 21 Krefman, Nathaniel I., ...... 384C Jansen, J., ...... 76A Kassir, Yona, ...... 121A* Krol, Kamil,...... 246C, 247A Jaquenoud, Malika, ...... 173B Kast, Alene, ...... 327C* Kruglyak, Leonid,...... 26 Jarosz, Daniel, ...... 43* Katta, Sreenivasulu S, ...... 17 Krumlinde, Daniel, ...... 326B Jaspersen, Sue, ...... 17 Kaur, Jaswinder, ...... 132C Kuang, Meihua Christina, ...... 342C* Jaspersen, Sue, ...... 63* Kay, Daniel, ...... 364A Kuang, Zheng, ...... 313A Jäverlin, Aino, ...... 299B Kaya, Alaattin, ...... 365B* Kubeck, Lauren N., ...... 417C Jeffery, E., ...... 363C* Keil, Christopher, ...... 412A* Kucerova, Helena, ...... 83B Jeffery, Eric, ...... 297C Kellems, Martha, ...... 276C* Kuehn, Rauel, ...... 368B Jeffery, Eric W., ...... 370A Kelly, Kristen, ...... 329B Kuehner, Jason N., ...... 239B* Jeong, EunMi, ...... 85A Kempf, Claudia, ...... 201C* Kuelbs, Stephanie D., ...... 417C Jeong, Jeong-Hoon, ...... 322A* Kennedy, Scott, ...... 237C Kuijpers, N. G., ...... 102C Jessulat, Matthew, ...... 145A Kershisnik, Emma, ...... 273C Kumar, Abhay, ...... 385A Jessulat, Matthew G. M., ...... 135C* Kerwin-Iosue, Christine L., ...... 87C Kumar, Anuj, ...... 366C* Jester, Benjamin, ...... 447C* Kessler, Haeja A., ...... 195C Kumar, Deepak, ...... 304A* Jiang, Hanxiao, ...... 301A* Khakhina, Svetlana, ...... 162C Kumar, Sanjeev, ...... 35* Jiang, Yu, ...... 165C* Khaku, Sakina K., ...... 235A Kunkel, Joe, ...... 160A Jiao, Zhihua, ...... 75C Khanna, Varun, ...... 255C Kupiec, Martin, ...... 245B Jin, Chunyan, ...... 162C Khmelinskii, Anton, ...... 148A, 438C* Kurischko, Cornelia, ...... 286A* Jin, H.,...... 185B, 302B* Kievit, Robyn, ...... 429C Kuzmin, Elena, ...... 57* Jin, Huiyan, ...... 309C Kim, Bomi,...... 400A Kuznetsov, Evgeny, ...... 83B* Jin, Liang, ...... 120C* Kim, Daehee, ...... 202A* Kvint, Kristian, ...... 308B Jinks-Robertson, Sue, ...... 244A Kim, Eun Jung, ...... 203B* Kwak, Grace, ...... 392B Johansen, Jesper, ...... 200B* Kim, Ikjin, ...... 439A* Johnson, C., ...... 53 Kim, Jane C., ...... 238A* L Johnson, Cole, ...... 366C Kim, J. H., ...... 176B La Ferla, Marco, ...... 398B Johnson, Paige, ...... 276C Kim, Jinmi,...... 322A, 323B Lafon, Anne, ...... 95B Johnson, Richard,...... 112A Kim, Ji Yoon, ...... 203B Lai, Jefferson, ...... 106A Johnston, Mark, ...... 101B Kim, Junwon, ...... 48 Lal, Sneha, ...... 193A, 205A* Johnston, Stephen D., ...... 166A* Kim, Myung Sup, ...... 303C* Lam, Kenny, ...... 309C Jonassen, I., ...... 331A Kim, Young-Mo, ...... 433A Lancaster, Samuel M., ...... 367A* Joseph, Fraulin, ...... 29 King, Heather, ...... 417C Landry, Benjamin, ...... 4 Joseph, Lucy, ...... 429C Kingsbury, Joanne M., ...... 167B* Landry, Christian, .....9, 421A*, 431B* J. Purzycka, Katarzyna, ...... 267C Kinkhabwala, Ali, ...... 148A Lang, Jackie, ...... 224B* Jung, Daehee, ...... 323B* Kintaka, R., ...... 204C* Lang, Moritz, ...... 214A Jung, Jong-hwan, ...... 322A Kirrmaier, Daniel, ...... 438C Lanzillotta, Cristina M.,...... 229A Jung, Paul,...... 353B Kishony, Roy, ...... 55 Laprade, Lisa, ...... 448A* Jung, Paul P., ...... 71B, 364A* Kitzman, Jacob, ...... 64 Larabell, Carolyn A., ...... 16 Jung, Soo-Jin, ...... 136A* Klar, Amar J. S., ...... 122B* Larango, M., ...... 54 J. van der Klei, Ida, ...... 35 Klaus, Bernd, ...... 299B Larsen, Camilla E., ...... 395B* Klein, Sarah J., ...... 235A Larsen, Camilla J., ...... 395B K Klipp, Edda, ...... 179B Larson, Anna, ...... 171C Kabashi, Merita,...... 316A Knop, Michael, ...... 148A*, 438C Lau, Rebecca, ...... 178A Kachroo, Aashiq H., ...... 66* Knowels, Gary, ...... 237C Laurent, Jon M., ...... 66 Kahana-Edwin, Smadar, ...... 121A Kobor, Michael S., ...... 232A Laval, Guillaume, ...... 358A Kakavandi, M., ...... 331A Koch, Elizabeth, ...... 39 Law, Michael J., ...... 283A* Kalia, Raghav, ...... 20 Koch, Lori, ...... 109A* Laxman, Sunil, ...... 84C* Kaluarachchi Duffy, Supipi, ..... 272B* Kodedova, Marie, ...... 215B Leach, Michelle, ...... 168C* Kaluzna, Iwona, ...... 325A Kohlwein, Sepp D., ...... 2* Leach, Michelle D., ...... 183C Kamara, Sorna, ...... 44 Kohrn, Brendan, ...... 237C Lebo, K. J., ...... 264C Kamei, Yuka, ...... 209B Kolehmainen, Kathleen L., ...... 149B* Leducq, Jean-Baptiste,...... 431B Kang, JiWon, ...... 58 Konstantinidou, G., ...... 21 Lee, Chien-Der, ...... 45* Kannan, N., ...... 54 Korona, Ryszard,...... 350B, 351C Lee, Jaehoon, ...... 317B
53
Speaker and Author Index This index includes names in alphabetical order of all invited authors, and co-authors published in this book. The number following a name refers to the abstract’s program number. An asterisk denotes a presenting author. Platform Presentations: 1-69, Poster Presentations 70A-465C.
Lee, Jee Yeon, ...... 400A ...... 198C, 218B, 266B, 399C, 415A Matunis, M. J., ...... 208A Lee, Ying Peng, ...... 195C Loewith, R.,...... 21 Maufrais, Corinne, ...... 358A Lee, Yuseon, ...... 323B Loewith, Robbie, ...... 184A Maurer, Matt,...... 406A Leitner, A., ...... 21 López-Malo, María, ...... 359B Maxwell, Colin S., ...... 343A* Leitner, Erich, ...... 325A Lu, J., ...... 208A May, Christopher K., ...... 16 Leman, Adam R., ...... 305B* Lubin, Johnathan W., ...... 30* May, Patrick, ...... 462C Lemon, Laramie, ...... 263B* Lubitz, Timo, ...... 179B May, Robin, ...... 358A Lenz, Peter, ...... 181A Lucas, Candida, ...... 190A Mayor, Thibault, ...... 51, 218B, 266B Leone, Sarah G., ...... 341B Luchniak, Anna, ...... 50 Mayorga, Maria, ...... 448A Leone, Sarah Grace, ...... 306C* Ludlow, Catherine, ...... 370A* Mazanka, Emily M., ...... 32* Leskoske, Kristin, ...... 169A* Ludwig, K., ...... 331A McCleary, David, ...... 284B* Lev, Ifat, ...... 457A* Luke, Brian, ...... 378C McClure, Allison, ...... 49* Leverich, C., ...... 442A Lundblad, Vicki, ...... 30 McClure, Kelsi, ...... 276C Levy, Julia, ...... 424A Luo, Xiangxia, ...... 160A McCroskey, Scott, ...... 17 Levy, Sasha F., ...... 420C McElroy, Taylor, ...... 277A* Lew, Daniel, ...... 49 M McGoff, Kevin A., ...... 305B Lewellyn, Eric B., ...... 384C Ma, L., ...... 240C* McMahon, Conor, ...... 18 Lewis, Jeff, ...... 375C Ma, Lina, ...... 266B McManus, Charles,...... 324C Lewis, Jeffery A., ...... 312C MacCoss, Michael, ...... 112A McMaster, Christopher, ...... 68* Lewis, Jeffrey A., ...... 441C MacGilvray, Matthew, ...... 7, 171C* McMaster, C. R., ...... 386B, 408C Li, Boyang, ...... 159C MacGurn, Jason, ...... 157A McMurray, M., ...... 53* Li, Hunter,...... 69 Machado, Caio M., ...... 86B McMurray, Michael, ...... 111C Li, J., ...... 396C* MacQueen, A., ...... 114C McNabney, Sean, ...... 455B Li, Sheena, ...... 372C Macreadie, Ian G., ...... 405C McQueen, Jennifer, ...... 191B Li, Sheena C., ...... 397A* Magee, Alexander, ...... 392B McQueen, Jennifer A.,...... 399C* Li, Shuang, ...... 206B* Magwene, Paul, ...... 343A M. Dudley, Aimée, ...... 462C Li, Song, ...... 451A Magwene, Paul M., ...... 347B Meadows, Adam, ...... 106A, 301A Li, Susan, ...... 399C Maharrey, Crystal, ...... 453C Measday, V.,...... 458B Li, X., ...... 443B Mahatdejkul-Meadows, T, ...... 106A Measday, Vivien, ...... 191B, 266B* Li, Xiyan, ...... 207C* Maia de Olivera, T., ...... 21 Medina, D. A., ...... 291C Li, Y., ...... 185B Makanae, K., ...... 204C Medina, Daniel A., ...... 373A Li, Yong, ...... 14 Malik, Harmit, ...... 58, 430A Mefford, M. A., ...... 264C Liachko, Ivan, ...... 346A, 432C* Malik, I., ...... 302B Mehra, Upasana, ...... 137B* Libkind, Diego, ...... 24, 349A Mallick, Emily, ...... 335B Meinhardt, Friedhelm, ...... 327C Ligoxygakis, Petros, ...... 428B Mandell, Dan, ...... 447C Mejia, Matthew, ...... 417C Lin, Feng, ...... 268A Mao, Cungui, ...... 85A* Melamed, Daniel, ...... 344B* Lin, Gen, ...... 368B* Mapa, Claudine, ...... 4 Mellor, Joseph, ...... 38 Lindahl, Lasse, ...... 196A, 287B Marcotte, Edward M., ...... 66 Meluh, P. B.,...... 208A* Lindley, Harrison, ...... 276C Markowitz, Tovah, ...... 119B Mena, A., ...... 345C* Lindquist, Susan, ...... 43, 60 Marsh, E., ...... 442A Mendelsohn, Bryce, ...... 95B Lindstrom, D., ...... 138C Marshall, Sarah, ...... 276C, 277A Meneghini, Marc, ...... 13, 116B Linster, Carole L., ...... 71B, 364A Marston, Adele, ...... 33* Menon, Anant K., ...... 200B Lipton, Mary S., ...... 433A Martens, Joseph, ...... 310A Mercatanti, Alberto, ...... 398B Lisby, Michael, ...... 379A Martin, Elizabeth, ...... 424A Merhi, A., ...... 142A Lithgow, Gordon J., ...... 150C Martin, Joel A., ...... 375C Merhi, Ahmad, ...... 152B Liu, Beidong, ...... 326B Martínez-Pastor, M.Teresa, ...... 373A Merrill, Anna, ...... 7 Liu, Elizabeth M., ...... 417C Martiniuk, J., ...... 458B* Meslin, Camille, ...... 123C* Liu, Jian, ...... 295A Martins, Antonio, ...... 172A* Metz, Thomas O., ...... 433A Liu, Tzu-Ning, ...... 281B Martins, Larissa S., ...... 86B Meurer, Matthias, ...... 438C Liu, Zhengchang, ...... 307A* Martin-Yken, Hélène,...... 295A Meusburger, Madeleine, ...... 184A Ljungdahl, Per, ...... 172A Maruvka, Yosef E., ...... 55 Miao, Yu-Hsuan, ...... 139A Ljungdahl, Per O., ...... 170B* Masneuf-Pomarede, I, ...... 429C Michaelis, Vladimir K., ...... 60 Lloyd, Paul,...... 318C Masoom, Rehan, ...... 308B Michielin, Olivier, ...... 436A Lo, Dara, ...... 369C* Masuda, Claudio A., ...... 86B* Michor, Franziska, ...... 55 Lo, Russel, ...... 357C Matecic, Mirela, ...... 217A Milbury, K., ...... 241A* Lo, Yi-Chen, ...... 281B Mathew, V.,...... 241A Miles, Shawna, ...... 6 Lobanov, Alexei V., ...... 365B Mathew, Veena, ...... 248B Miller, Aaron W., ...... 346A* Lodovichi, Samuele, ...... 398B* Matityahu, Avi, ...... 227B Miller, Christina, ...... 344B, 439A Loewen, Christopher, ...... 51, 191B Mattiazzi Usaj, Mojca, ...... 371B* Miller, Matthew, ...... 110B
54
Speaker and Author Index This index includes names in alphabetical order of all invited authors, and co-authors published in this book. The number following a name refers to the abstract’s program number. An asterisk denotes a presenting author. Platform Presentations: 1-69, Poster Presentations 70A-465C.
Milman, N., ...... 240C H. M. L. P., ...... 92B Ontoso, David, ...... 11 Minakova, Maria, ...... 49 Ndlovu, Thulile, ...... 211A* Opoku, Kwaku, ...... 33 Mine-Hattab, Judith, ...... 29 Neal, Erin M., ...... 87C* Orgil, Ola, ...... 227B Minic, Zoran, ...... 135C Neiman, Aaron, ...... 120C, 124A Orlando, Kelly A., ...... 341B Minikel, Samantha, ...... 229A Nelson, Christopher S., ...... 150C Orr, Galya, ...... 433A Mink, Daniel, ...... 325A Nelson, Justin, ...... 372C, 397A Osada, Hiroyuki, ...... 372C Miranda, M., ...... 425B Nelson, ZW, ...... 442A Ouenzar, Faissal, ...... 263B Mirkin, Sergei M., ...... 238A Newman, H. A., ...... 208A Oughtred, Rose, ...... 409A Mitchell, J. A., ...... 54* Newman, Jack, ...... 446B Outhay, Malena, ...... 277A Mitchell, Jessica, ...... 267C, 269B Newton, Michael A., ...... 360C Outlaw, Darryl, ...... 449B Mitchell, Leslie, ...... 381C Neymotin, Benjamin, ...... 289A Mitsunaga, Erin,...... 374B Nguyen, Alex, ...... 57 P Mobley, James, ...... 391A Nguyen, Hanh, ...... 82A Pachulska-Wieczorek, Katarzyna,267C Modi, Meet, ...... 277A Nguyen, Lisa, ...... 30 Pagliuca, Cinzia, ...... 221B Moffat, Jason, ...... 369C Nguyen, M., ...... 261C Paliwal, Swati, ...... 348C* Moir, Robyn D., ...... 317B Nguyen, Michelle, ...... 368B Palkova, Zdena, ...... 73A, 81C, Møller, Henrik D., ...... 242B* Nguyen, Son, ...... 393C ...... 83B, 91A*, 104B, 328A Momeni, Babak,...... 461B Nguyen Ba, Alex, ...... 1 Pandey, Dharmendra, ...... 132C Monteleone, Nicholas, ...... 229A Nickels, B., ...... 302B Park, Jae-Sook, ...... 124A* Montero-Lomelí, Mónica, ...... 86B Nickerson, Kenneth W., ...... 92B Parreiras, Lucas, ...... 349A Moore, Claire, ...... 239B Niederer, R. O., ...... 264C Parrou, JL., ...... 93C, 94A Morales, Rita, ...... 117C Nielly-Thibaut, Lou, ...... 431B Parsons, Lance, ...... 242B Moreno Torres, Marta, ...... 173B* Nielsen, Martin W., ...... 379A Parts, Leopold, ...... 452B Moritz, Robert, ...... 112A Nishida, Y., ...... 54 Parvin, Jeffrey, ...... 64 Moriya, H.,...... 204C Nishida, Yuri, ...... 267C*, 269B Pascoe, Natasha, ...... 403A* Morozov, Alexandre, ...... 294C Nishimura, Akira, ...... 100A Pasion, S. G., ...... 261C Mosbach, Valentine, ...... 255C Nislow, C., ...... 362B, 410B Paskov, Kelley, ...... 411C Mösch, Hans-Ulrich, ...... 181A Niu, Qiankun, ...... 14 Paskov, Kelley M., ...... 459C* Mösch, H.-U., ...... 219C Nourani, Amine, ...... 277A Pathirana, Ruvini U., ...... 92B* Moses, Alan, ...... 1, 57 Novarino, Daniele, ...... 378C Patil, Prashanti, ...... 195C Moshgabadi, Noushin, ...... 69 Nunnari, Jodi, ...... 135C Patra, Biranchi N., ...... 37, 404B* Mueller, Erica N., ...... 233B, 250A Nyamugenda, Eugene, ...... 276C Patton-Vogt, J., ...... 133A Muir, Alexander, ...... 174C* Nyström, Thomas, ...... 326B Paulissen, Scott, ...... 125B* Mukai, Yukio, ...... 209B* Paulovich, Amanda, ...... 437B Muller, G., ...... 103A O Paulson, Carsten, ...... 56 Muller, Heloise, ...... 59* O'Donnell, Allyson,...... 123C, Paw, J., ...... 362B Müller, Monika, ...... 325A ...... 141C, 332B Payen, Celia, ...... 25*, 99C, 108C, Munson, Mary, ...... 20* O'Donnell, Allyson F., ...... 146B ...... 228C, 338B Murashige, S., ...... 118A Oeffinger, Marlene, ...... 416B Peach, Sally, ...... 290B* Murphy, Alex, ...... 273C* Oh, Yoomi,...... 88A* Pecora, Mia,...... 424A Murphy, Erin, ...... 50 Ohnuki, S., ...... 362B Pedeville, Deanna, ...... 243C Murphy, Helen A., ...... 347B* Ohnuki, Shinsuke, ...... 42*, 89B Peel, Michael, ...... 306C Murray, Debra,...... 347B Ohtsu, Iwao, ...... 100A Pelechano, Vicente, ...... 299B Murray, Marlene N., ...... 400A* Ohya, Y., ...... 362B Péli-Gulli, Marie-Pierre, ...... 173B Mutukrishnan, Nandhini, ...... 309C Ohya, Yoshikazu, ...... 42, 89B, 105C Pellman, David, ...... 55 Muzi-Falconi, Marco, ...... 378C Ojini, Irene, ...... 65 Penner, M., ...... 133A Muzzey, Dale, ...... 26 Okada, Hiroki, ...... 89B* Perez-Ortin, J. E., ...... 291C* Myers, Chad, ...... 372C Oke, Ashwini, ...... 28 Pérez-Ortín, Jose E., ...... 373A Myers, Chad L., ... 39, 57, 397A, 426C Olayanju, Mobolanle, ...... 402C* Pérez-Torrado, Roberto, ...... 434B Myers, Kevin S., ...... 422B* Oldani, Amanda, ...... 221B Peria, W., ...... 158B Oling, David, ...... 308B* Peris, David, ...... 24 N Oliver, Kathryn E., ...... 394A Peris Navarro, David, ...... 349A* NaghdiGheshlaghi, Zahra, ...... 401B* Omholt, SW, ...... 331A Perlman, David, ...... 8 Nakayama, Yasumune, ...... 209B Omnus, Deike J., ...... 170B Pesce, G., ...... 158B Nambiar, M., ...... 240C O'Neil, Nigel, ...... 69 Peters, L., ...... 143B Nambiar, Mridula, ...... 225C* Ong, Giang, ...... 25 Peters, Theodore W., ...... 150C* Narula, Ashrut, ...... 13 Ong, Ta-chung, ...... 60 Peterson, Timothy R., ...... 191B Natkanska, Urszula, ...... 210C* Onishi, Masayuki, ...... 90C* Petitjean, M., ...... 93C*, 94A* Navarathna, Dhammika Onn, Itay, ...... 227B* Petkova, Mima, ...... 163A
55
Speaker and Author Index This index includes names in alphabetical order of all invited authors, and co-authors published in this book. The number following a name refers to the abstract’s program number. An asterisk denotes a presenting author. Platform Presentations: 1-69, Poster Presentations 70A-465C.
Petty, Emily L., ...... 95B* Ramachandran, ...... 383B, 406A Pflieger, David, ...... 311B Subramaniam, ...... 174C Rout, Michael, ...... 20, 416B Phanse, Sadhna, ...... 135C Rammo, D., ...... 19 Rovinskiy, Nikolay S., ...... 375C* Piccirillo, Sarah,...... 117C Rappsilber, Juri, ...... 33 Roy, A., ...... 176B* Pichler, Harald, ...... 325A Ratushny, Alexander, ...... 416B Roy, Jagoree, ...... 9* Pickens, Lauren,...... 106A Ratushny, Alexander V., ...... 451A Rubenstein, Eric M., ...... 151A* Pieczynska, Magdalena, ...... 350B* Raupach, Elizabeth A., ...... 310A* Rubin, Eitan, ...... 259A Piening, Brian, ...... 437B Ravindran, R., ...... 97A* Rudolf, Fabian, ...... 214A* Pillus, Lorraine, ...... 95B, 280A Ray, Animesh, ...... 37, 404B Rudra, Soumya, ...... 230B Pimentel, Felipe S. A., ...... 86B Rayannavar, Vinayak, ...... 406A Rufiange, Anne, ...... 277A Pineda, Jose, ...... 337A Reavey, Caitlin, ...... 27* Rush, Sarah,...... 329B Pinto, Ines, ...... 226A* Recamier, Vincent, ...... 29 Russo, Mariano, ...... 376A Piotrowski, Angela L., ...... 96C* Recor, Chelsea, ...... 256A Rutledge, Mark T., ...... 376A* Piotrowski, Jeff, ...... 372C*, 397A Regenberg, Birgitte, ...... 242B, Rymond, Brian C., ...... 177C Pitoniak, Andrew, ...... 161B ...... 379A, 395B Piya, Gunjan, ...... 233B Reid, Robert J. D., ...... 383B, 406A* S Plech, Marcin, ...... 351C* Reisser, Cyrielle, ...... 353B Sabatini, David M.,...... 191B Pogachar, Jamie, ...... 228C* Reiter, Wolfgang, ...... 293B Sadhu, Meru, ...... 465C Polk, P., ...... 97A Reményi, Attila, ...... 1 Saha, A., ...... 54 Pollard, Daniel, ...... 352A* Rems, Ana, ...... 98B* Saha, Agniva, ...... 269B* Pomraning, Kyle R., ...... 433A* Rich, Matthew S., ...... 99C* Sahni, Nidhi, ...... 409A Pons, Carles, ...... 39 Richard, Guy-Franck, ...... 255C* Saiki, Kyohei, ...... 100A* Poon, Pak P., ...... 408C Richardson, Lauren, ...... 212B* Sakhaneko, Nikita, ...... 368B Porzoor, Afsaneh, ...... 405C* Richmond, Philip A., ...... 55 Sakhon, Olivia S., ...... 417C Poshusta, Garrett, ...... 416B Rifkin, Scott, ...... 352A Saleem, Ramsey, ...... 416B Poti, Kristin, ...... 4 Riley, Nicholas M., ...... 422B Saliba, Elie, ...... 152B* Pracheil, Tammy, ...... 307A Rine, Jasper, ...... 10, 212B, Sampaio, José, ...... 349A Prevost, Christopher T., ...... 243C* ...... 275B, 278B, 279C, 282C, Sampaio, José Paulo, ...... 24 Prévost, Martine, ...... 152B ...... 284B, 334A, 456C Sanchez, Joseph Carlo, ...... 262A* Pringle, John, ...... 90C Rispal, D., ...... 21 Sanchez, Monica, ...... 356B Proctor, Michael, ...... 368B Rivera, Sam, ...... 392B Sandler, Inga,...... 259A Pronk, J. T., ...... 102C Robinson, G., ...... 21 Sands, B., ...... 158B Prosser, Derek, ...... 141C Robinson, L. C., ...... 97A San-Luis, B., ...... 362B Prouteau, Manoël, ...... 21* Rocchi, Giulia, ...... 398B San-Segundo, Pedro, ...... 11 Puig, Sergi, ...... 373A Rochet, Jean-Christophe, ...... 147C Santiago-Cartagena, E, ...... 177C* Pujol-Carrion, Nuria, ...... 163A Rodriguez, Kenny R., ...... 417C Santoro, Irma, ...... 244A Pulver, Rebecca, ...... 270C Rodriguez-Medina, José R., ...... 177C Santos, Sean M., ...... 449B* Roe, Jung Hye, ...... 203B Santos, V. A. F. F. M., ...... 407B Q Roe, Jung-Hye, ...... 136A Sapiro, Guillermo, ...... 270C Qi, Min, ...... 329B Roelants, Françoise, ...... 169A, 174C Sarangapani, Krishna, ...... 33 Qin, Hong, ...... 423C* Rogers, Jason V.,...... 18*, 126C* Sardi, Maria, ...... 349A Qiu, C., ...... 302B Rogers, Richard, ...... 416B Sardi, Maria I., ...... 375C, 377B* Qiu, Chenxi, ...... 309C* Rohacz, Nicholas A., ...... 417C Sartorel, Elodie A., ...... 178A* Qiu, Hongfang, ...... 320B Rolfes, Ronda J., ...... 213C* Sato, Trey, ...... 349A Queitsch, Christine, ...... 333C Romero, Antonia Maria, ...... 373A* Sato, Trey K., ...... 375C, 422B Querol, Amparo, ...... 434B Ronald, Davis, ...... 445A Schacherer, Joseph, ...... 311B*, Quon, Evan, ...... 200B Rong-Mullins, Xiaoqing, ...... 374B* ...... 340A, 353B* Rose, Mark, ...... 128B Schackwitz, Wendy S., ...... 375C R Rose, Mark D., ...... 18, 48*, Schaffitzel, C., ...... 21 Rabinowitz, J., ...... 78C ...... 126C, 129C Scheifele, Lisa Z., ...... 229A* Rabinowitz, Joshua, ...... 8 Rosebrock, Adam, ...... 13, 62*, Schieler, A., ...... 78C Radhakrishnan, Aparna, ...... 361A ...... 88A, 107B Schlecht, U., ...... 425B* Raghuram, Nandini, ...... 155B Rosebrock, Adam P., ...... 80B Schlecht, Ulrich, ...... 418A, 452B Raghuraman, M. K., ...... 262A Roskelley, Calvin, ...... 399C Schlissel, Gavin S., ...... 278B* Rahnamoun, Homa, ...... 352A Ross, Angus, ...... 180C Schmidt, Simon, ...... 454A Rai, R., ...... 298A Rossi, Danuza, ...... 197B Schmitt, M. J., ...... 19 Rai, Rajendra, ...... 175A* Roth, F., ...... 425B Schneider, Brandt L., ...... 414C Rajaei, Naghmeh, ...... 268A* Roth, Frederick, ...... 38, 409A Schneider, Kyle, ...... 1 Raju, Shravya L., ...... 424A* Rothstein, Rodney, ...... 29, Schneiter, Roger, ...... 173B, 436A
56
Speaker and Author Index This index includes names in alphabetical order of all invited authors, and co-authors published in this book. The number following a name refers to the abstract’s program number. An asterisk denotes a presenting author. Platform Presentations: 1-69, Poster Presentations 70A-465C.
Scholes, Amanda N.,...... 312C* Sirotkin, Vladimir, ...... 134B Sternglanz, Rolf, ...... 120C Schraffl, Andrea, ...... 421A Sirr, Amy, ...... 370A, 462C Steunou, Anne-Lise, ...... 421A Schubert, Max, ...... 446B Sirr, Amy Carol, ...... 127A* Stevens, David, ...... 435C Schuldiner, Maya, ...... 380B Sison, E. S., ...... 261C Stilwell, Jessica, ...... 414C Schultz, Eric, ...... 237C Sitko, Katherine A., ...... 389B Stirling, P., ...... 241A Schurmann, Martin, ...... 325A Skibbens, Robert V., ...... 230B* Stirling, Peter C., ...... 231C, 248B* Schwartz, Katja, ...... 358A Skoneczna, Adrianna,...... 210C, Stisher, Chandler, ...... 449B Schwartz, S., ...... 302B ...... 246C*, 247A* Stoliartchouk, Alexei, ...... 413B, 465C Schweizer, Lilian Marry, ...... 315C Skoneczny, Marek, ...... 210C, St. Onge, Robert, ...... 418A Schweizer, Michael, ...... 315C ...... 246C, 247A St. Onge, Robert P., ...... 452B Sclafani, Robert A., ...... 244A* Skotheim, Jan M., ...... 3 St.Onge, R. P., ...... 425B Scott, Adrian, ...... 450C* Skupin, Alexander, ...... 364A Stovicek, Vratislav, ...... 81C, Seip, J., ...... 199A Slaughter, Brian, ...... 17, 63 ...... 104B, 328A Seiser, Robert M., ...... 96C, 464B* Sliva, Anna, ...... 313A* Stribny, Jiri, ...... 434B* Selmecki, Anna M., ...... 55* Slubowski, Christian, ...... 125B Strich, Randy S., ...... 36* Sen, Neelam D., ...... 167B Smith, Daniel, ...... 453C Strynatka, Katherine A., ...... 408C* Seo, Youngdae, ...... 136A Smith, Daniel L., ...... 217A Stuecker, Tara N., ...... 312C Sere, Yves, ...... 200B Smith, Elizabeth A., ...... 16 Stultz, Laura, ...... 391A, 463A Sertour, Natacha, ...... 358A Smith, Gerald R.,...... 225C, 253A Stumpf, Michael, ...... 419B Severson, Amber L., ...... 235A Smith, Gerry, ...... 58, 430A Styles, Erin B., ...... 378C* SGD Project, ...... 387C Smith, Gerry R., ...... 240C, 252C Su, Xiaofeng, ...... 249C* Shah, Ajit, ...... 193A, 205A Smith, J., ...... 425B Subramanian, Viji, ...... 119B Shah, Kartik A., ...... 238A Smith, Jean, ...... 128B* Sun, Song, ...... 409A* Shah, Khyati, ...... 186C Smith, Jeffrey S., ...... 217A Sun, Xiaoji, ...... 119B Shah, Khyati H.,...... 5* Smith, Jennifer J., ...... 451A* Sun, Xuepeng, ...... 314B* Shanmuganatham, Karthik, ...... 175A Smith, Jeremy, ...... 161B Sundaran, Venkatraghavan, ...... 163A Shapira, R., ...... 460A* Smith, Justin D., ...... 452B* Sung, Shen-Shu, ...... 393C Sharifpoor, Sara, ...... 197B Smith, Keston, ...... 117C Sunjevaric, Ivana, ...... 406A Sharma, Nimisha,...... 304A Smith, Michael J., ...... 29* Sunnerhagen, P., ...... 331A Shashkova, Sviatlana, ...... 179B* Smoyer, Christine,...... 63 Sunnerhagen, Per, ...... 326B Shemesh, Keren, ...... 245B* Smoyer, Christine J., ...... 17* Sunshine, Anna, ...... 25 Shen, Yi, ...... 326B Smyth, Jason, ...... 347B Sunshine, Anna B., ...... 346A Shendure, Jay, ...... 64, 432C Snowdon, Chris, ...... 180C Suresh, S., ...... 425B Sherbina, Katrina, ...... 417C Snyder, M., ...... 443B Suresh, Sundari, ...... 418A, 452B Sherlock, Gavin, ...... 358A, 420C Snyder, Michael, ...... 207C, 374B, Sutter, Benjamin, ...... 84C Shi, J., ...... 440B* ...... 435C Sychrova, Hana, ...... 215B* Shi, Lei, ...... 84C Solis-Escalante, D., ...... 102C* Sychrová, Hana, ...... 190A Shi, Qian, ...... 186C Soloveychik, Maria, ...... 13* Sylvester, Kayla,...... 24, 349A Shimoi, Hitoshi, ...... 105C Song, Qingxuan, ...... 366C Shin, John, ...... 399C Sørensen, Laura G. R., ...... 379A* T Shore, David, ...... 378C Sorenson, Amber, ...... 55 Tackett, Jessalyn, ...... 276C Shoresh, Noam, ...... 55 Sorscher, Eric J., ...... 394A Tagaki, Julie, ...... 52 Shou, Wenying, ...... 337A, 461B* Souza-Moreira, T. M., ...... 407B* Tai, Anna, ...... 106A Shrestha, Kriti, ...... 221B Spealman, Pieter J., ...... 324C* Takagi, Hiroshi, ...... 100A, 105C Shteyman, Alan,...... 324C Sporer, Abigail J., ...... 129C* Talevich, E., ...... 54 Sia, Rey A., ...... 243C Srinivas, N.,...... 331A Tamada, Yoshihiro, ...... 209B Sides, Rebecca E., ...... 441C* Stagljar, Igor, ...... 177C Tan, Guihong, ...... 38, 409A Sidhu, Sachdev, ...... 403A Stambuk, B. U., ...... 103A* Tan, Kaiquan, ...... 74B Siegal, Mark, ...... 206B Starita, Lea, ...... 64* Tan, Zhihao, ...... 297C, 462C* Siegal, Mark L., ...... 23 Stark, Michal, ...... 121A Tang, Alvin,...... 309C Sieverman, Kathryn, ...... 10 Stefan, Christopher, ...... 157A Tao, Luan, ...... 329B Sieverman, Katie, ...... 279C* Stefan, Eduard, ...... 421A Tatchell, K., ...... 97A Simpkins, Scott, ...... 372C, 397A Steffes, Jenna, ...... 250A Tate, Jennifer J., ...... 175A Simpson-Lavy, Kobi, ...... 101B* Steidle, Elizabeth, ...... 213C Tate, J. J., ...... 298A Simpson-Lavy, Kobi J., ...... 153C* Stein, Richard, ...... 128B Tavassoli, Shabnam, ...... 51, 218B Sing, Tina,...... 378C Steiner, Walter, ...... 256A* Taylor, Matthew, ...... 22 Sing, T. L., ...... 362B Steinmetz, Lars,...... 299B, 368B Tekkedil, Manu, ...... 368B Singh, Badri Nath, ...... 15 Stelling, Joerg, ...... 214A Teste, MA., ...... 93C, 94A Sinha, Himanshu, ...... 361A Stephany, Jason J., ...... 388A Teytelman, Lenny, ...... 413B*, 465C*
57
Speaker and Author Index This index includes names in alphabetical order of all invited authors, and co-authors published in this book. The number following a name refers to the abstract’s program number. An asterisk denotes a presenting author. Platform Presentations: 1-69, Poster Presentations 70A-465C.
Thayer, NH, ...... 138C*, 442A* Vega, Alondra J.,...... 417C Wheelan, Sarah J., ...... 229A Theesfeld, Chandra, ...... 409A Vélez-Segarra, Vladimir, ...... 177C White, Melissa G., ...... 117C Thore, S., ...... 21 Verma, Yash, ...... 137B Whitfield, Shawn T., ...... 155B* Thorner, J., ...... 53 Vidal, Marc, ...... 409A Wierman, Margaret B., ...... 217A* Thorner, Jeremy, ...... 52, 141C, Viitanen, Paul, ...... 329B Wilkening, Stefan, ...... 368B ...... 169A, 174C, 178A Vincenten, Nadine, ...... 33 Wilkinson, Derek,...... 328A* Thorpe, Peter, ...... 222C Visram, Myriam, ...... 2 Williams, Jaime, ...... 263B Thurtle, Deborah, ...... 275B Viterbo, David, ...... 255C Willis, Ian M., ...... 317B* Tien, Jerry, ...... 108C, 110B Vizeacoumar, FS, ...... 138C Wilson, Thomas, ...... 366C Timmons, Garrett, ...... 174C Vlaming, Hanneke, ...... 11 Wilson, Timothy M., ..... 235A, 250A* Tinberg, Christine, ...... 447C Vlasblom, James, ...... 135C Wimmer, Miriam, ...... 325A Toczyski, David Paul, ...... 40* Voelz, Kerstin, ...... 358A Winston, Fred, ...... 27 Tokuda, S., ...... 118A Volpe, Marina, ...... 194B, 457A W. Jeffery, Eric, ...... 462C Tomlinson, Shannon M., ...... 95B Vuillemin, Marlène, ...... 295A Wohlbach, Dana J., ...... 375C, 377B Tong, Jeffery, ...... 145A Vvedenskaya, I., ...... 302B Wolfe, Ken, ...... 161B Tong, Kevin, ...... 230B Wong, A K. O., ...... 51, 198C, 218B* Torres, Nikko P., ...... 41* W Wong, Catherine C., ...... 384C Torres-Machorro, Ana Lilia, ...... 280A Wachsmuth, L., ...... 54 Wong, Edith, ...... 318C* Torres-Quiroz, Francisco, ...... 421A Waddington, Lynne J., ...... 405C Wong, L. H., ...... 410B* Trueheart, Joshua, ...... 448A Wakefield, Jon, ...... 47 Wozniak, N.,...... 219C* Tsai, Chai-jui, ...... 147C Walker, Daisy, ...... 213C Wriessnegger, Tamara, ...... 325A Tsegaye, Yoseph, ...... 106A Walker, Jennifer, ...... 332B Wright, Jill N., ...... 414C* Tsong, Annie, ...... 106A Walters, Alison, ...... 115A Wu, Jingyan, ...... 46*, 288C Tu, Benjamin, ...... 45, 84C Walters, Alison D., ...... 16* Wu, Kati, ...... 106A* Tucey, Timothy M., ...... 30 Walther, Andrea, ...... 354C Wu, Wei-Hua, ...... 14* Tyagi, Tanya, ...... 409A Walther, Andre P., ...... 235A Wykoff, Dennis, ...... 87C, 306C Wan, Yao, ...... 46, 288C* Wykoff, Dennis D., ...... 319A*, 341B U Wang, Chao-Wen, ...... 139A* Ugbogu, Eziuche Amadike, ...... 315C* Wang, H., ...... 292A* X Umbreit, Neil, ...... 110B* Wang, Meng, ...... 90C Xie, Jinglin L., ...... 183C* Umbreit, Neil T., ...... 32 Wang, Wei, ...... 14 Xu, Lan, ...... 106A Unal, Elcin, ...... 113B Wang, Wen, ...... 39 Xu, Mengshu, ...... 13 Ünal, Elçin, ...... 130A Wang, Zhe, ...... 314B Xu, Ruijuan, ...... 85A Unruh, Jay, ...... 17, 63 Wang, Zhishi, ...... 360C Xu, Y., ...... 78C Usaj, Matej,...... 39, 57, 371B, 426C* Wanka, Stefanie, ...... 9 Usher, J., ...... 363C Warringer, J., ...... 291C, 331A Y Usher, Jane,...... 428B Watanabe, Daisuke, ...... 100A, 105C* Yam, Phoebe, ...... 28 Webb, Kristofor, ...... 95B Yamaguchi, Takafumi, ...... 38 V Weems, A., ...... 53 Yang, Fan, ...... 409A Vachova, Libuse, ...... 73A, Weems, Andrew, ...... 111C* Yang, G. X., ...... 443B* ...... 81C, 83B, 91A, 104B*, 328A Wei, Karen, ...... 416B Yang, Jianjun, ...... 329B* Vadaie, Nadia, ...... 157A Wei, Siwei, ...... 433A Yang, Kun, ...... 273C Vainorius, Gintautas, ...... 214A Weil, Dylan S., ...... 195C Yang, Xiaoxue, ...... 326B Valentini, Sandro R.,...... 197B Weill, Uri, ...... 380B Yashpal, FNU, ...... 320B* Valentini, S. R.,...... 407B Weinberg, Abigail P., ...... 336C Yates 3rd, John R., ...... 384C Vallabhaneni, Arjuna Rao, ...... 316A* Weinert, Corey, ...... 437B Ye, Qiaozhen, ...... 33 Valsakumar, Veena, ...... 217A Weiss, E., ...... 76A Ye, Rick, ...... 329B Van Dalfsen, Kelsey, ...... 131B* Weiss, Eric, ...... 1* Ye, Tian, ...... 182B van der Felden, Julia, ...... 181A Weiss, Eric L., ...... 72C Yeh, Brian, ...... 1 Vanderhooft, Jordan,...... 392B Weisser, Sarah, ...... 181A* Yellman, Christopher, ...... 66 van der Merwe, George, ...... 180C* Weissman, Jonathan S., ...... 26 Yeong, Foong May, ...... 70A, 74B, VanderSluis, Benjamin, ...... 39*, 57 Welch, Aaron, ...... 216C* ...... 192C van Leeuwen, Fred, ...... 11* Welkenhuysen, Niek, ..... 179B, 182B* Yerlikaya, Seda, ...... 184A* van Leeuwen, Jolanda, ...... 38*, 401B Wellington, Melanie, ...... 270C Yi, Jae Kyo, ...... 85A van Pel, Derek, ...... 69 Wendland, Beverly, ...... 141C Yi, Song, ...... 409A van Welsem, Tibor, ...... 11 Wendland, Jürgen, ...... 201C Yofe, Ido, ...... 380B* Varela, Cristian, ...... 454A Wendland, Jurgen W., ...... 354C* Yogev, O., ...... 143B Vashistha, Nidhi, ...... 154A* Wensel, Jocelyn, ...... 404B Yong, Chris, ...... 360C Vax, A., ...... 94A Westfall, Patrick, ...... 106A Yong, Mun Hong, ...... 330C*
58
Speaker and Author Index This index includes names in alphabetical order of all invited authors, and co-authors published in this book. The number following a name refers to the abstract’s program number. An asterisk denotes a presenting author. Platform Presentations: 1-69, Poster Presentations 70A-465C.
York, Kerri,...... 260B, 290B Yoshida, Minoru, ...... 372C, 397A Yoshinaga, A., ...... 133A Young, Alexandria, ...... 12 Young, Barry, ...... 266B, 415A* Young, Barry P., ...... 51, 218B Young, David, ...... 344B Yu, Analyn,...... 409A Yu, Haiyuan, ...... 427A* Yu, Jonathan, ...... 58 Yuan, Wenjie, ...... 165C
Z Zahner, Christopher, ...... 414C Zakrzewski, Bethany, ...... 256A Zamir, Lyad, ...... 259A Zamparo, Lee, ...... 378C Zanders, Sarah, ...... 430A Zanders, Sarah E., ...... 58* Zanelli, C. F., ...... 407B Zanelli, Cleslei F., ...... 197B Zanotelli, Vito, ...... 8 Zappulla, D. C.,...... 264C* Zaslaver, Olga, ...... 62, 107B* Zellnig, Guenther, ...... 325A Zelter, Alex, ...... 32, 108C, 112A* Zeppel, Ryan, ...... 429C Zeyl, Cliff W., ...... 347B Zhang, A., ...... 185B* Zhang, Bo, ...... 186C* Zhang, Li, ...... 193A, 205A Zhang, Ruoyu, ...... 355A* Zhang, Ying, ...... 62 Zhang, Zhaolei, ...... 135C, 378C Zhao, Karen L., ...... 188B Zhao, Wei, ...... 25 Zheng, Mei-Yi, ...... 140B*, 336C Zheng, Wei, ...... 374B Zhou, Yan, ...... 105C Zhu, Q., ...... 199A Zieler, Helge, ...... 37* Zitnik, Marinka, ...... 371B Zoet, Vincent, ...... 436A Zupan, Blaz, ...... 371B Zweifel, Stephan, ...... 257B*
59
Yeast Database Genetic Index to Abstracts
This is an index of genes mentioned in the abstracts. The current Yeast Database approved gene symbol is given in each case; non-current symbol synonyms or full names used in the abstracts are not indexed.
The index was prepared computationally based solely on the YBgn & gene symbol information provided by authors during abstract submission. GSA is not responsible for any omissions from the index where authors did not provide information, nor for any incorrect indexing where genes stated to feature in an abstract do not actually appear. Numbers following each term refer to abstract program numbers: 1--69 are platform presentations and 70- 465 are poster presentations.
AAC3 ...... 187A Brl1 ...... 17 CK2 ...... 303C acc1 ...... 115A BRR2 ...... 401B Cka2 ...... 7 ACC1 ...... 402C Brr6 ...... 17 CKS1 ...... 406A Ace2 ...... 1 BSD2 ...... 25 CLB2 ...... 82A ace2 ...... 76A Bsp1 ...... 164B CLB3 ...... 113B Act1 ...... 202A BUD3 ...... 82A CLN1 ...... 323B act1 ...... 273C BUL1 ...... 142A, 152B Cln1 ...... 331A add66 ...... 217A BUL2 ...... 142A, 152B cln1 ...... 3 ADE2 ...... 307A Bzz1 ...... 164B cln2 ...... 3 ade4 ...... 217A CAC1 ...... 220A Cln2 ...... 331A ade6 ...... 256A CAF20 ...... 323B Cln3 ...... 6 adh4 ...... 107B CAN1 ...... 65, 152B, 295A cmp2 ...... 174C ado1 ...... 217A CAT1 ...... 322A cna1 ...... 174C AIM44 ...... 90C cbk1 ...... 76A Cna1 ...... 164B ALY1 ...... 142A CBK1 ...... 72C, 286A Cna2 ...... 164B ALY2 ...... 142A Cbk1 ...... 1 Cnl1 ...... 145A anp1 ...... 89B cce1 ...... 257B CNN1 ...... 224B apm1 ...... 155B cdc10 ...... 111C Cnn1 ...... 221B apm2 ...... 155B Cdc10 ...... 52 cof1 ...... 273C ARF1 ...... 189C CDC10 ...... 53 COM2 ...... 121A aro10 ...... 434B CDC11 ...... 53 cox18 ...... 107B ART1 ...... 152B cdc11 ...... 111C cox9 ...... 107B ASF1 ...... 220A Cdc11 ...... 52 CSE4 ...... 31, 223A, 271A ASI1 ...... 170B CDC12 ...... 53 cse4 ...... 222C ASI2 ...... 170B cdc12 ...... 111C csk1 ...... 319A ASI3 ...... 170B Cdc12 ...... 52 Cta1 ...... 202A atf1 ...... 256A, 434B CDC13 ...... 264C ctf19 ...... 457A ATF1...... 448A Cdc14 ...... 7 CTF4 ...... 383B atf2 ...... 434B cdc14 ...... 273C CTF7/ECO! ...... 230B ATG ...... 139A CDC15 ...... 70A ctp1 ...... 240C ATH1 ...... 78C cdc24 ...... 261C CTS1 ...... 72C atp1 ...... 107B Cdc24 ...... 161B Ctt1 ...... 202A AVO1 ...... 21 CDC28 ...... 2, 4, 82A CUP1 ...... 295A AVO2 ...... 21 cdc3 ...... 111C CUP1-1 ...... 242B AVO3 ...... 21 CDC3 ...... 53 CUP1-2 ...... 242B BARD1 ...... 64 Cdc3 ...... 52 CYC8 ...... 307A bcy1 ...... 443B cdc42 ...... 389B CYK3 ...... 90C bdf1 ...... 424A CDC42 ...... 49, 96C DAM1 ...... 110B, 112A Bdp1 ...... 317B Cdc42 ...... 161B dam1 ...... 457A BEM1 ...... 96C CDC48 ...... 144C DBF4 ...... 244A Bem4...... 161B CDC5 ...... 16, 406A DHH1 ...... 323B bim1 ...... 158B CDC55 ...... 293B DIG1 ...... 462C BIT2 ...... 21 CDC7 ...... 244A dis3 ...... 241A BIT61 ...... 21 cds1 ...... 261C dld2 ...... 107B Bli1 ...... 145A Chc1 ...... 164B DMC1 ...... 119B Bls1 ...... 145A CHL1 ...... 230B DNF1 ...... 178A BMH1 ...... 166A chs1 ...... 89B DNF2 ...... 178A BNI4 ...... 82A Chs2 ...... 74B DNF3 ...... 178A Bni5 ...... 52 CIA2 ...... 194B DNM1 ...... 36, 243C BRCA1 ...... 64 CIN5 ...... 417C DOA10/SSM4 ...... 151A BRE1 ...... 11 CIN8 ...... 70A DON1 ...... 125B
60
Yeast Database Genetic Index to Abstracts
DOT1 ...... 11, 232A GAP1 ...... 142A, 152B, 242B Hsp31 ...... 147C Dot6 ...... 160A GAT1 ...... 298A HSP31 ...... 210C DRS2 ...... 178A GCN2 ...... 165C HSP82 ...... 43, 296B dsl1 ...... 18 gcn4 ...... 285C HTA1 ...... 232A dsn1 ...... 222C GCN4 ...... 320B HTA2 ...... 232A, 242B DSN1 ...... 224B GCN5 ...... 95B, 159C HTB1 ...... 95B DUN1 ...... 305B GEA1 ...... 96C HTB2 ...... 170B, 242B EAP1...... 323B GEA2 ...... 96C HTZ1 ...... 223A Ecm21 ...... 146B GIM3 ...... 53 Hxk1 ...... 182B ECM3 ...... 310A GIS1 ...... 193A, 293B Hxk2 ...... 182B EDC3 ...... 286A, 322A GLC7 ...... 97A, 144C HXT1 ...... 345C ELG1 ...... 245B glc7 ...... 179B, 184A HXT2 ...... 345C eme1 ...... 253A GLG2 ...... 105C HXT3 ...... 345C ENA1 ...... 242B Glk1 ...... 182B HXT4 ...... 345C ENA2 ...... 242B gln3 ...... 175A HXT5 ...... 345C ENA5 ...... 242B GLN3 ...... 417C HXT6 ...... 242B, 345C END3 ...... 22 Glr1 ...... 202A HXT7 ...... 242B, 345C EPL1 ...... 280A GPA2 ...... 323B hym1 ...... 76A epo1 ...... 51, 218B Gpd1 ...... 419B idp1 ...... 107B erd2 ...... 19, 389B Gpd2 ...... 419B IDP2 ...... 282C ERG12 ...... 80B GPR1 ...... 207C idp2 ...... 107B ERG2 ...... 215B Gpx3 ...... 202A IFH1 ...... 303C ERG24 ...... 215B GRR1 ...... 27 IME1 ...... 117C, 121A, 129C ERG3 ...... 215B Gsh1 ...... 202A IME2 ...... 117C, 129C ERG4 ...... 215B Gsh2 ...... 202A IME4 ...... 129C ERG5 ...... 215B gt2 ...... 101B IML1 ...... 90C ERG6 ...... 215B Gtr1 ...... 84C Iml1 ...... 84C ESA1...... 280A GTR1 ...... 167B INN1 ...... 90C ESP1 ...... 266B GTR2 ...... 167B INP1 ...... 35 EST1 ...... 30, 263B guk1 ...... 389B INP2 ...... 35 Est1 ...... 264C Gyl1 ...... 74B Inp53 ...... 164B EST2 ...... 30, 263B, 264C Gyp5 ...... 74B IPL1 ...... 97A, 113B EST3 ...... 30 hac1 ...... 86B IQG1 ...... 90C far1 ...... 3 HAC1 ...... 290B IRA2 ...... 22 fas1 ...... 115A hap4 ...... 355A IRE1 ...... 156C fas2 ...... 115A HAP4 ...... 307A ire1 ...... 86B FBA1 ...... 276C HCM1 ...... 4 IRR1 ...... 227B FBP1 ...... 236B HEK2 ...... 462C ist2 ...... 218B fbp1 ...... 392B hem25...... 386B JHD2 ...... 283A fks1 ...... 89B HHF1 ...... 279C Jhd2 ...... 13 FLO1...... 219C HHT2 ...... 276C, 277A KAR4 ...... 129C FLO10...... 219C HMLALPHA2 ...... 279C kar5 ...... 126C flo11 ...... 379A HMO1 ...... 417C KEL1 ...... 128B FLO11...... 44, 48, 104B, 219C, 283A HO ...... 118A, 279C kes1/osh4 ...... 200B FLO5...... 219C HOF1 ...... 90C KGD1 ...... 402C flo8 ...... 379A Hog1 ...... 7 kic1 ...... 76A FLO8...... 22, 48, 159C HOG1 ...... 121A, 156C Kif4A ...... 194B FLO9...... 219C HOM3 ...... 320B KIP3 ...... 50 fms1 ...... 92B HOM6 ...... 320B KOG1 ...... 165C FPK1 ...... 178A HOP1 ...... 119B kre6 ...... 89B fus1 ...... 313A hpr1 ...... 362B, 424A Kss1 ...... 161B FUS1 ...... 128B Hrd1 ...... 154A KSS1 ...... 48, 121A, 159C FUS2 ...... 128B HRD1 ...... 151A Kxd1 ...... 145A FUS3 ...... 48, 121A, 123C Hrd3 ...... 154A lac1 ...... 174C fus3 ...... 3 hrr25 ...... 186C LAC1 ...... 188B fyv6 ...... 217A hsf1 ...... 168C LAG1 ...... 188B gal1 ...... 86B HSF1 ...... 105C, 391A lag1 ...... 174C GAL11 ...... 293B HSH155 ...... 248B LCB1 ...... 188B GAL3 ...... 342C HSK3 ...... 110B LCB4 ...... 188B gal4 ...... 447C hsp104 ...... 201C Ldb19 ...... 141C, 146B gal7 ...... 86B HSP104 ...... 43, 53, 296B leu3 ...... 217A GAL80 ...... 342C Hsp26 ...... 442A LOC1 ...... 265A
61
Yeast Database Genetic Index to Abstracts
LSM1 ...... 323B NBA1 ...... 90C POL32 ...... 244A, 271A LSM4 ...... 41 ndc10 ...... 222C PRE6 ...... 328A LST8 ...... 21 NDC80 ...... 112A, 113B, 224B prm3 ...... 126C Maf1 ...... 317B Ndc80 ...... 221B PRP3 ...... 401B MAM3 ...... 328A ndj1 ...... 114C, 251B PRP31 ...... 401B mat1 ...... 122B ndt80 ...... 114C PRP6 ...... 401B MATA ...... 118A NDT80 ...... 116B PRP8 ...... 401B MATALPHA ...... 118A NEM1...... 173B, 187A psh1 ...... 222C Mbp1...... 6 NIS1 ...... 90C PSH1 ...... 31, 223A MCA1 ...... 322A Nnf1 ...... 221B PTR3 ...... 27, 170B MCD1 ...... 227B NOT1 ...... 286A PUF3 ...... 45, 291C, 299B, 361A MCD1/SCC1 ...... 230B NPR1 ...... 152B rad3 ...... 261C MCK1 ...... 191B Npr2 ...... 84C RAD5 ...... 232A MCM4 ...... 234C Npr3 ...... 84C RAD51 ...... 29, 119B, 279C MCM5 ...... 244A NTE1 ...... 159C RAD52 ...... 29, 247A, 279C, 378C mdh1 ...... 107B NUF2 ...... 113B Rad53 ...... 6 mdh2 ...... 107B num1 ...... 51 RAD53 ...... 41, 305B MDM32 ...... 366C nup2 ...... 251B RAD61 ...... 227B MDV1 ...... 36 NUP84 ...... 249C RAS2 ...... 48, 159C mec1 ...... 229A ole1 ...... 168C RBD2 ...... 384C MED13 ...... 36, 162C OPI1 ...... 159C rec12 ...... 252C, 256A mei4 ...... 253A ORC4 ...... 262A rec25 ...... 252C MEK1 ...... 119B ORC6 ...... 262A rec27 ...... 252C Met16 ...... 202A pab1 ...... 344B rec8 ...... 252C met17 ...... 337A PAH1 ...... 173B, 187A, 191B RED1 ...... 119B MET18 ...... 194B pan1 ...... 19 ref2 ...... 424A MF(ALPHA)1 ...... 118A PAT1 ...... 166A, 286A, 323B reg1 ...... 179B MFA1 ...... 118A Pat1 ...... 5 reg2 ...... 179B MID2 ...... 177C PBP1 ...... 361A REV3 ...... 232A, 244A mig1 ...... 179B pcr1 ...... 256A REV7 ...... 244A Mig1 ...... 182B PDA1 ...... 402C Rfa1 ...... 235A, 250A mit1 ...... 379A PDB1 ...... 402C RFA1 ...... 233B MIT1 ...... 27 PDC2 ...... 306C RFA2 ...... 233B MKT1 ...... 361A PDR5 ...... 407B Rfa2 ...... 235A, 250A mob2 ...... 76A PDS1 ...... 266B RFA3 ...... 233B Mob2...... 1 PDS5 ...... 230B Rfa3 ...... 250A MOT3 ...... 27 PEA2 ...... 366C rgt1 ...... 101B mph1 ...... 231C pep3 ...... 133A RGT2 ...... 176B MPH1 ...... 279C pep5 ...... 424A rim101 ...... 379A MPK1 ...... 117C, 121A PEX14 ...... 35 RIM101 ...... 159C Mps1 ...... 109A PEX3 ...... 35 RIM15 ...... 105C mps3 ...... 126C PFK1 ...... 102C Rim15 ...... 316A Mrh1 ...... 442A PFK2 ...... 102C RIM4 ...... 129C Msa1 ...... 6 PGM1 ...... 105C rim8 ...... 379A Msa2 ...... 6 pgm1 ...... 86B RLG1 ...... 46 MSB2 ...... 157A PGM2 ...... 105C RLM1 ...... 117C MSH2 ...... 65, 234C pgm2 ...... 86B Rod1 ...... 141C msh6 ...... 237C PHD1 ...... 462C Rog3 ...... 141C msl1 ...... 362B pho1 ...... 319A rot1 ...... 389B MSN2 ...... 27, 103A, 105C, 206B, PHO5 ...... 341B ROX1 ...... 197B ...... 213C, 293B, 294C pho7 ...... 319A rpb7 ...... 304A Msn2 ...... 316A PHO85 ...... 320B RPD3 ...... 159C, 280A MSN4 ...... 105C, 206B pka1 ...... 392B Rpd3 ...... 316A Msn4 ...... 316A PKC1 ...... 177C, 197B RPH1 ...... 293B mss11 ...... 379A Pma1 ...... 399C RPL7A...... 265A MSS11 ...... 22, 166A PMA1 ...... 34, 276C rpn11 ...... 389B MTG3 ...... 137B PMU1 ...... 341B RPO21 ...... 302B mtw1 ...... 222C PMU2 ...... 341B RPS0B ...... 265A mug20 ...... 252C pol1 ...... 229A RPS31 ...... 290B mus81 ...... 253A, 261C POL2 ...... 234C rps6a ...... 184A MYO1 ...... 90C pol2 ...... 237C rps6b ...... 184A Myo1...... 52 POL30 ...... 244A rsc1 ...... 424A
62
Yeast Database Genetic Index to Abstracts rsc2 ...... 362B SNC1 ...... 149B Swi6 ...... 6 rsp5 ...... 19, 168C SNF1 ...... 156C Tah18 ...... 100A Rsp5 ...... 141C, 146B snf1 ...... 179B, 281B tao3 ...... 76A RSP5 ...... 142A, 152B Snf1 ...... 7, 101B, 182B, 199A TCO89 ...... 277A RTG1 ...... 159C snf12 ...... 424A Tdp1 ...... 272B rtn1 ...... 18 SNF2 ...... 205A tec1 ...... 379A RTS1 ...... 95B SNF3 ...... 176B TEC1 ...... 121A, 181A RTT107 ...... 232A snf3 ...... 101B TEL1 ...... 28 Rvs161 ...... 74B snf8 ...... 379A TFG2 ...... 302B Rvs167 ...... 74B, 164B Snn1 ...... 145A TGL3 ...... 2 SAM37 ...... 46, 288C SOD1 ...... 322A TGL4 ...... 2 SAN1 ...... 462C sog2 ...... 76A THI10 ...... 306C SCC2...... 227B, 230B SPAC19A8.02 ...... 134B THI2 ...... 306C Sch9 ...... 84C, 316A Spc24 ...... 221B THI3 ...... 306C SCH9 ...... 167B SPC24 ...... 113B THI4 ...... 306C scs2 ...... 51, 218B SPC25 ...... 113B Thr1 ...... 442A Scs2 ...... 198C Spc25 ...... 221B TIF4631 ...... 344B ScSTL1 ...... 190A SPC97 ...... 108C TIF4632 ...... 344B SDS3 ...... 280A SPC98 ...... 108C TIF51A /HYP2 ...... 197B sec1 ...... 20 spo11 ...... 252C TIF51B /ANB1 ...... 197B sec4 ...... 20 SPO14 ...... 124A TLC1 ...... 264C sec6 ...... 20 SPO7 ...... 173B, 187A Tod6 ...... 160A SEN15...... 288C SPO71 ...... 124A TOM70 ...... 46, 288C SEN2...... 288C SPO77 ...... 125B TOP1 ...... 65 SEN34...... 288C SPS1 ...... 125B TOR1 .. 91A, 165C, 167B, 173B, 207C SEN54...... 288C SPS4 ...... 120C Tor1 ...... 160A, 316A ser3 ...... 107B SPT16...... 31, 276C Tor2 ...... 169A SER3 ...... 310A SPT3 ...... 269B TOR2 ...... 21 set1 ...... 13 SRB10/CDK8 ...... 320B TOS4 ...... 4 SET1 ...... 11 SRB8 ...... 307A TOS8 ...... 462C sey1 ...... 18 SRS2 ...... 238A, 279C Tpk1 ...... 160A SFG1 ...... 462C ssa1 ...... 388A TPK1, PKA ...... 5 SFL1 ...... 159C, 366C, 462C SSA1 ...... 43 Tpk2 ...... 160A SGS1 ...... 378C SSD1 ...... 286A tpk3 ...... 379A SHB17 ...... 88A Ssd1 ...... 1 Tpk3 ...... 160A Sho1 ...... 161B SSN3 ...... 162C, 283A TPS1 ...... 78C, 93C, 94A SHP1 ...... 144C SSN8 ...... 36, 162C, 283A tps2 ...... 424A shp1 ...... 184A SSY1 ...... 170B TRL1 ...... 290B SHR5 ...... 328A SSY5 ...... 170B, 172A TRP1 ...... 103A Shs1 ...... 52, 198C Ste11 ...... 161B TRR1 ...... 22 shs1 ...... 51, 111C, 218B STE12 ...... 121A, 129C, 181A, Trx2 ...... 202A SIM1 ...... 83B ...... 323B, 333C TSL1 ...... 206B SIN4 ...... 27, 307A STE18 ...... 48 TUB1 ...... 50 SIP3 ...... 134B STE2 ...... 118A TUB2 ...... 50 sip5 ...... 101B Ste2 ...... 141C Ty1 ...... 229A SIR1 ...... 220A, 334A STE3 ...... 118A UBA1 ...... 97A SIR2 . 207C, 275B, 279C, 284B, 334A STE4 ...... 48, 49 ubc4 ...... 19 sir2 ...... 308B STE5 ...... 48, 178A ubp3 ...... 308B SIR3 ...... 275B, 279C, 334A STP1 ...... 170B ubr2 ...... 222C SIR4 ...... 275B, 279C, 334A SUA7 ...... 302B UGP1 ...... 105C SIT4 ...... 152B SUC2 ...... 149B UPF1 ...... 220A SIW14 ...... 213C SUL1 ...... 25, 99C, 228C, 346A URA3 ...... 445A SKO1 ...... 121A SUL2 ...... 346A Usa1 ...... 154A sla1 ...... 19 SUN4 ...... 83B UTH1 ...... 83B Sla1 ...... 164B sup35 ...... 60 Vab2 ...... 145A SLT2 ...... 162C Sup35 ...... 147C vhs1 ...... 101B SLX4...... 232A Sur7 ...... 442A vhs3 ...... 443B SLX5...... 249C SWE1 ...... 2, 48, 95B, 406A VID22 ...... 378C SLX8...... 249C SWI3 ...... 205A vph2 ...... 424A Smf1 ...... 145A SWI4 ...... 121A Vps1 ...... 74B SMK1 ...... 116B Swi4 ...... 6 VPS13 ...... 124A, 149B SMT3 ...... 208A SWI6 ...... 246C Vps27 ...... 145A
63
Yeast Database Genetic Index to Abstracts
Whi2 ...... 331A WSC1 ...... 177C Xbp1 ...... 6 XRN1 ...... 46, 220A, 269B, 290B YAK1 ...... 166A Yap1 ...... 202A yck1 ...... 101B yck2 ...... 101B YDJ1 ...... 53 YDR332w ...... 132C YDR336w ...... 132C YHP1 ...... 4 YHR177W ...... 462C YIL166C ...... 346A YKU80 ...... 263B, 378C yop1 ...... 18 YOR019W ...... 27 YOR1 ...... 394A YOX1 ...... 4 YPC1 ...... 85A ypk1 ...... 174C, 184A Ypk1 ...... 169A ypk2 ...... 184A ypk3 ...... 184A YRR1 ...... 374B YSP1 ...... 134B ZAP1...... 417C zip1 ...... 114C ZrSTL1 ...... 190A ZrSTL2 ...... 190A
64
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EMD Millipore, the M mark and CellASIC are registered trademarks of Merck KGaA, Darmstadt, Germany. © 2014 EMD Millipore Corporation, Billerica, MA, USA. All rights reserved. BS GEN-14-10342 07/2014 Two Journals, One Mission
Scientific peer-review and publishing is a critical component of your research process that deserves to be handled with care, responsiveness, and speed. Trust your articles to GSA’s peer-edited sister journals. Your peers – practicing scientists – manage the review and make all decisions on manuscripts. We publish cross-journal article blocks including Genomic Selection, QTL mapping in multi-parental population, Mouse Collaborative Cross, Genetics of Sex Determination, and others.
One month from submission until first decision means timely discovery of your research. AndG3 and GENETICS articles feature interactive, one-click links to FlyBase, plus Altmetric statistics, and, in mid-2014, ORCID IDs to link all your research output. Want to see your artwork on the cover? Submit an entry! Not sure if your work is appropriate for GENETICS or G3? Submit a pre- submission inquiry. Need to fast-track a paper? Let us know. VOLUME 194 • ISSUE 1 • PAGES• 1 ISSUE • 1–290 VOLUME194
GENETICS MAY 2013 • VOLUME 194 • ISSUE 1 • www.genetics.org GENETICS
DECEMBER 2013 • VOLUME 3 • ISSUE 12 • www.g3journal.org
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Perspectives: Darwin’s illnesses MAY 2013 Breaking chromosomes Battling repeats How genes flow Our Neanderthal ancestry
Why submit to G3? G3 provides a forum for the Why submit to GENETICS? To communicate publication of high‐quality research that generates significant, novel findings in genetics and genomics useful genetic and genomic findings. Topics include to a wide range of scientific investigators.GENETICS genome maps, single gene studies, genome‐wide also publishes Methods, Technology and Resources; association and QTL studies, mutant screen reports, significant software advances; Toolbox reviews; sequence of novel species, plus datasets, research in Educational Primers; Commentaries, Perspectives, human and medical genetics, and more. G3 believes and more. that rapid dissemination of its published articles is the necessary foundation for analysis that leads to • Fast decisions - average 34 days from submission to mechanistic insights. first decision • Thoughtful, thorough reviews improve the impact of • Fully open-access journal your research • Rapid turnaround on submitted manuscripts • Clear decisions by peer-editors • Early online publication within 2 weeks of acceptance; • Space to tell the whole story - no limits on page length, final publication within 4-8 weeks tables, or figures • Well-described studies with useful results • Early online within 2 weeks of acceptance • Mutant Screen Report format for quick submissions • Open-access option Because your research is important to you, it’s im- • Highlights and press releases promote exceptional portant to us. Don’t let your work get lost in a sea of stories and discoveries papers! Submit to G3, increase your visibility, and www.genetics.org support the genetics community. www.g3journal.org
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2016 Allied Genetics Conference Ad.indd 1 1/21/14 11:49 AM
DMM ABOUT 8.25" x 10.75".pdf 1 03/07/2014 14:51 Yeast Genetics Meeting • July 29–August 3, 2014 • University of Washington, Seattle For up-to-date information visit y.gsaconf.org
SCHEDULE AT-A-GLANCE WEDNESDAY, 8:15 pm–11:00 7:15 pm–8:15 7:00 pm–7:15 6:00 pm–7:00 TUESDAY, JULY29 9:00 am–11:00 SUNDAY, AUGUST3 6:00 pm–12:00am 5:30 pm–5:45 4:00 pm–5:30 2:00 pm–3:30 10:30 am–12:00noon 8:30 am–10:00 SATURDAY, AUGUST2 7:30 pm–11:00 6:00 pm–7:30 4:00 pm–5:30 2:00 pm–3:30 11:15 am–12:00noon 10:30 am–11:15 8:30 am–10:00 FRIDAY, AUGUST1 7:30 pm–11:00 6:00 pm–7:30 3:15 pm–4:45 1:30 pm–3:00 10:30 am–12:00noon 8:30 am–10:00 THURSDAY, JULY31 7:30 pm–11:00 6:00 pm–7:30 4:00 pm–5:30 2:00 pm–3:30 11:15 am–12:00noon 10:30 am–11:15 8:30 am–10:00 JULY 30 Dinner Epigenetics andPost-TranscriptionalRegulation Next GenerationGenetics Jeremy Thorner, University ofCalifornia,Berkeley Lifetime AchievementAward Aging Chromosome Dynamics Poster Session2andExhibits GSA CareerDinner Dinner Advocacy Presentation • • • Workshops: Dissecting ComplexTraits Trafficking andCellularArchitecture Poster Session1andExhibits “How toGetPublished”Presentation Dinner of GeneralMedicalSciences,NIH Special PresentationbyJonLorsch,DirectoroftheNationalInstitute Temporal andSpatialControlofChromatin George Church,Harvard University Lee HartwellLecture Environmental SensingNetworks Cell CycleTransitions Opening Mixer Olga Troyanskaya, PrincetonUniversity Ira HerskowitzAwardLecture Welcome andOpeningRemarks First TimeAttendees Social Chair: Genomics andProteomics Conference Party Banquet – Elizabeth W. JonesAward forExcellence inEducationtoMalcolmCampbell Presentation ofEdward Novitski Prize toCharlieBoonePresentationof GSA Awards Yeast andHumanDisease New Technologies Chromosome RearrangementsandPolyploidy Spatial Relationships Poster Session3andExhibits Plenary andWorkshopforUndergraduateResearchers Computational ToolsatSGD Beyond Cerevisiae Corey Nislow
Winge-Lindegren Address,Anita Hopper,OhioStateUniversity
y.gsaconf.org HUB Grand Ballroom HUB, Room 250 Meany Theater Meany Theater Meany Theater Meany Theater Meany Theater Lobby Meany Theater Meany Theater Meany Theater Lobby Meany Theater Meany Theater HUB Grand Ballroom Meany Theater Meany Theater Meany Theater Meany Theater Meany Theater HUB Grand Ballroom HUB Den Meany Theater Meany Theater Meany Theater Meany Theater Meany Theater HUB Grand Ballroom HUB Den Kane HallRoom 210 Kane HallRoom 210 Kane HallRoom 220 Kane HallRoom 120 Meany Theater Meany Theater July 29–August 3,2014 PROGRAM BOOK Yeast GeneticsMeeting The GeneticsSocietyofAmericaConferences • University ofWashington, Seattle