excellence in life sciences

Reykjavik Helsinki Oslo

EMBO facts & figures  Tallinn Stockholm Copenhagen Vilnius Dublin Amsterdam Berlin Warsaw London Brussels Prague Bratislava Paris Luxembourg Budapest Bern Vienna Ljubljana Zagreb

Rome Madrid Ankara Lisbon Athens Valletta Jerusalem

New Delhi

Singapore

EMBO facts & figures  HIGHLIGHTS  CONTACT EMBO & EMBC

Membership  new members from  countries in Europe and eight EMBO Young Investigators Associate Members from , Japan, Lithuania, Singapore and EMBO Installation Grants the were elected. EMBO Women in Science Fellowships Long-Term Fellowships opened for applications all year round EMBO Courses & Workshops and new eligibility criteria for Short-Term Fellowships were EMBO Keynote Lectures R Gerlind Wallon EMBO Scientific Publications I introduced. C H Programme Manager Bernd Pulverer A  Long-Term,  Short-Term and  Advanced Fellowships R Maria Leptin Deputy Director Head D were awarded. EMBO Director +     +     B BE E N 6 N TON 201 Young Investigators and Lithuania joined the Installation Grants scheme.

LE Installation Grants H N  Young Investigators and  Installation Grantees became part ER 2016 of the EMBO community. Science Policy EMBO co-organised a workshop on science advising in Europe. Eilish Craddock Personal Assistant to Science Policy Programme Manager Michele Gar nkel was EMBO Fellowships EMBO Scientific Publications the EMBO Director invited to represent EMBO on the European Commission’s Open David del Álamo Thomas Lemberger +     7th Science Policy Platform. Programme Manager Deputy Head The programme continued its work on research integrity, +     +     including presentations at European institutes and improve-

advancing the life sciences ments to the online training course. 2016 Courses & Workshops More than , participants attended  scienti c events. Mannheim  EMBO Laboratory Management Courses were held in Heidelberg and at six research institutes worldwide. 10 – 13 September Administration & Finance EMBO Global Activities EMBO Communications The th EMBO Meeting in Mannheim concluded the meeting Bernhard Huber Luis Valente Tilmann Kießling series. Head Head Head +     +     +     Global Activities Malta and Lithuania become EMBC Member States. EMBO partners with the /DBT India Alliance to deliver three life science meetings per year in India. Awards The EMBO Gold Medal was awarded to Richard Benton and Ben Lehner. EMBC EMBO Membership & EMBO Council & Committees EMBO Science Policy Elections received the FEBS | EMBO Women in Science Award. Gitta Bourke Michele Garfinkel Volker Wiersdorff EMBO Press EMBO Press extended its scooping protection policy to preprints. Administrator Programme Manager Head SourceData The SmartFigures lab application of SourceData was developed +     +     +     in collaboration with publishing house Wiley and launched at The EMBO Meeting.

Complete list of EMBO staff in Heidelberg on pages  . EMBO facts & figures 2016

EMBO promotes excellence in life sciences in Europe and beyond by recognizing and fostering talented scientists.

Since 1964, leading scientists are elected annually to become EMBO Members based on proven excellence in research. Members number more than 1700 today. 85 scientists from the EMBO membership have received the .

EMBO funding, training and networking activities attract thousands of scientists every year, promoting collaboration in all areas of life science research.

Four peer-reviewed journals span a broad spectrum of the life sciences and reflect how research is shaping the world.

The European Molecular Conference (EMBC), founded in 1969, is the intergovernmental funding body for EMBO comprising 29 member states including most of the European Union and some of the neighbouring countries.

Both EMBO and EMBC are driven by a common commitment to research at the European level. Their joint activities are characterized by quality and encouragement of co-operation within the scientific community.

EMBO facts & figures 2016 reports on the implementation of the EMBC General Programme and other EMBO activities. table of contents EMBO Fellowships 24 – 73 Preface 4 – 5 EMBO Long-Term Fellowships 24 – 41 EMBO actions in 2016 6 – 7 Statistics 24 – 25 EMBC actions in 2016 8 – 9 Awards 2016 26 – 38 Geographical distribution 2016 40 – 41 EMBO Advanced Fellowships 42 facts & figures 2016 EMBO Short-Term Fellowships 43 – 73 Statistics 43 EMBC Member States 12 – 13 Awards 2016 44 – 71 Delegates and Advisers 12 Geographical distribution 2016 72 – 73 Financial contributions 13 EMBO Young Investigators 74 – 81 EMBO Council & Committees 14 – 15 Young Investigators 2016 74 – 75 EMBO Council 2016 14 Young Investigators 2000 – 2016 76 – 77 EMBO Committees 2016 15 Applications and awards 2006 – 2016 78 EMBO Membership 16 – 19 Lectures 2016 79 – 81 EMBO Members 2016 16 – 18 EMBO Installation Grants 82 EMBO Associate Members 2016 19 Installation Grantees 2016 82

EMBO Scientific Publications 20 – 23 EMBO Courses & Workshops 83 – 88 Advisory Editorial Boards & Senior Editors of Practical Courses 2016 83 – 84 The EMBO Journal 20 Workshops 2016 84 – 85 EMBO reports 21 Conferences 2016 85 – 86 Molecular Systems Biology 22 Symposia 2016 87 EMBO Molecular Medicine 23 EMBO | FEBS Lecture Courses 2016 87 Global Exchange Lecture Courses 2016 87 Laboratory Management Courses 2016 88

EMBO Women in Science 89 – 93 Participation of women in EMBO activities: Statistics 89 – 93

EMBO Gold Medal 94 Gold Medalists 1986 – 2016 94

EMBO Keynote Lectures 95 – 97 Keynote Lectures 2016 95 – 97

EMBO Staff in Heidelberg 98 – 99

EMBO facts & figures 2016 | www.embo.org 3 Preface

I am pleased to present this collection of figures highlight- ing the variety, progress and impact of EMBO’s activities dur- ing 2016. Through its programmes and activities, EMBO con- tinued to support and connect life scientists across Europe and beyond. It was a particular pleasure to have three new countries join the EMBC. With Malta and Lithuania becoming EMBC Members States and India joining as Associate Member State, more researchers will be able to benefit from the support EMBO offers talented researchers at all stages of their careers. Demonstrating that excellence remains at the heart of the Maria Leptin organisation, EMBO welcomed 58 of the best life scientists EMBO Director from 18 countries to the EMBO Membership, and 25 of the most promising young group leaders were selected as EMBO Young Investigators. Celebrating individual achievements in the life sciences, we awarded the EMBO Gold Medal to Rich- ard Benton and Ben Lehner and the FEBS | EMBO Women in Science Award to Fiona Watt. EMBO’s funding programmes have continued to support talented researchers at all career stages. Looking ahead we must ensure that the EMBO Programmes stay at the forefront of supporting young scientists in building successful, inter- nationally mobile careers. With this in mind, we made the application process for Long-Term Fellowships more flexible by removing the application deadline, and introduced new eli- gibility criteria for the Short-Term Fellowships to make them available to more researchers in EMBC Member States. EMBO Courses & Workshops reach thousands of life scien- tists from across the globe every year at events where they can exchange information, receive training and connect with each other – and 2016 was no exception. The programme supported 92 events attended by more than 11,000 people. Additionally, members of the EMBO community were able to interact with

4 Preface | Maria Leptin EMBO facts & figures 2016 | www.embo.org peers outside their immediate research areas at the annual EMBO Press has continued to shape best practice in sci- EMBO Members’ Meeting and two ’ Meetings in Ger- entific publishing. Aspects of the EMBO Press ‘Transparent many and the USA. Process’ have been adopted by other journals. In addition, all 30 EMBO Laboratory Management Courses offered 478 EMBO Press publications introduced an extended scooping young researchers the opportunity to develop their manage- protection: manuscripts posted as preprints before submission ment and leadership skills, and we extended the portfolio to will not be rejected on the basis of similar findings published include courses on negotiation and self-leadership. Another by other researchers during the submission, peer-review or development saw the conclusion of The EMBO Meeting series revision process. with the seventh meeting in Mannheim. Acting on feedback The numbers in this publication speak for themselves: from the community, EMBO Council agreed to discontinue EMBO’s activities continue to positively influence the life sci- this large, multidisciplinary meeting – a decision that will en- ences in Europe and the rest of the world. The financial sup- able us to use our resources to explore new opportunities for port from the EMBC Member States, the guidance from EMBO bringing top science to the widest audiences. Examples of this Council, the dedication of the EMBO Members, and the en- are the joint ASCB | EMBO meeting in 2017 and the partner- thusiastic work of the EMBO office staff are vital for EMBO’s ship EMBO formed with the Wellcome Trust/DBT India Alli- ongoing success. I would like to thank everyone involved with ance to organize additional meetings in India. the organisation, and I look forward to working together to In addition to supporting researchers and stimulating the continue to deliver and develop EMBO’s activities. exchange of information, EMBO has successfully progressed its efforts to shape European science policy. Programme Man- ager Michele Garfinkel was invited to represent EMBO on the Open Science Policy Platform, a High-Level Advisory Group working directly with the Commissioner for Research, Science and Innovation, Carlos Moedas. EMBO representatives also discussed details of our policy work on responsible research Maria Leptin conduct and open science during a visit from the Commis- EMBO Director sioner to EMBO. Work in both of these areas has continued to expand. With a focus on supporting European researchers in conducting their research responsibly, the Science Policy Programme presented research integrity training sessions at two European research institutes and further improved the online training course. Together with publisher Wiley, EMBO launched an application of the SourceData project, SmartFig- ures Lab.

EMBO facts & figures 2016 | www.embo.org Preface | Maria Leptin 5 EMBO actions 2016

The EMBO Council met in April 2016. Major decisions are listed below along with other important EMBO actions not described elsewhere in this report.

➔➔EMBO OFFICERS & COUNCIL 2016 Council and membership elections ❚❚Carl-Henrik Heldin was re-elected as Chair of EMBO Council for 2017 and EMBO SECRETARY GENERAL Titia Sixma was elected as Vice Chair of EMBO Council for 2017. Carl-Henrik Heldin CHAIR, EMBO COUNCIL ❚❚Victor de Lorenzo and Regine Kahmann were re-elected to Council by the Geneviève Almouzni membership for the period 2017 – 2019. Claudio Sunkel (PT), Michael Hall (CH) VICE CHAIR, EMBO COUNCIL and Adrian Bird (UK) were newly elected for the same period. Karen B. Avraham Victor de Lorenzo Financial matters ❚❚The EMBO Council approved the accounts for 2015 and the budget for the EMBO Caroline Dean activities for 2017. This funding comes from the EMBC and is supplemented Denis Duboule with income generated by the EMBO publications. It is also used to pilot EMBO Anne Ephrussi activities that are not part of the EMBC General Programme. Regine Kahmann ❚❚Since 2009, the EMBO and EMBC accounts have been audited by KPMG Jürgen Knoblich (Switzerland). This audit is carried out in addition to the standard auditing László Nagy by a national audit court from one of the EMBC Member States (currently the Mart Saarma Netherlands). Paul Schulze-Lefert Titia Sixma Dimitris Thanos Other EMBO activities Awards MEMBERS OF EMBO COUNCIL ❚❚EMBO Council selected two scientists as the winners of the EMBO Gold Medal ➔➔See page 14 for a detailed list 2016: Richard Benton of the University of Lausanne (Switzerland) who showed of the 2016 EMBO Council that insect odorant receptors, the molecular detectors of scent, define a novel class of , with evolutionary roots in the common ancestor of animals and plants, and Ben Lehner of the Centre of Genomic Regulation (CRG), Barcelona, Spain, for his contributions to understanding the origins of phenotypic diversity in development and evolution (see page 94).

6 EMBO actions EMBO facts & figures 2016 | www.embo.org EMBO actions 2016

Other EMBO activities (continued)

❚❚The FEBS/EMBO Women in Science Award 2016 was awarded to Fiona Watt, ➔➔EMBO COMMITTEE CHAIRS 2016 Director of the Centre for Stem Cells and Regenerative Medicine at King’s College Jane Langdale London. Professor Watt received the award for uncovering the mechanisms that EMBO Membership Committee control mammalian epidermal renewal and differentiation, and for Sarah Bray EMBO Fellowship Committee discovering how these processes are deregulated in , wound healing and inflammatory skin disorders. Frank Uhlmann/Nils Brose EMBO Course Committee Meetings and training Gisou van der Goot EMBO Young Investigator Committee ❚❚The EMBO Meeting 2016 was held in Mannheim, Germany, from 10 to 13 Ivan Dikic September. EMBO Publications Advisory Board ❚❚New EMBO Members elected in 2015 and 2016 were welcomed to the ➔➔See page 15 for a complete list of organization during the EMBO Members’ Workshop held from 26 to 28 October the 2016 committee members 2016 in Heidelberg.

❚❚EMBO and EMBL held eight joint EMBO | EMBL Symposia in the EMBL Advanced ➔➔EMBO Council Administrator Training Centre in 2016. Gitta Bourke [email protected] ❚❚EMBO continued to participate in the activities and meetings of the Initiative for T +49 6221 8891 117 F +49 6221 8891 202 Science in Europe (ISE).

❚❚The EMBO Director and EMBO managers were engaged in a variety of other meetings and collaborations – in particular with the Federation of European Biochemical Societies (FEBS), the European Research Council (ERC) and the various programmes of the European Commission (EC).

❚❚EMBO provided management training for postdocs and group leaders by organizing 30 Laboratory Management Courses.

EMBO facts & figures 2016 | www.embo.org EMBO actions 7 EMBC actions 2016

➔➔EMBC OFFICERS 2016 The EMBC Delegates met in formal session in November 2016. The EMBC Finance Gerrit van Meer NETHERLANDS Committee met in June 2016 and the EMBC Strategic Working Party met in No- PRESIDENT vember 2016; the decisions and actions resulting from these meetings are listed Eirikur Steingrimsson ICELAND below. Charalambos Savakis GREECE VICE-PRESIDENTS Financial matters Patrick Cramer GERMANY ❚❚EMBC noted the reports of the external auditors and approved the accounts for SECRETARY GENERAL 2015. Troels Tvedegaard Rasmussen DENMARK FINANCE COMMITTEE CHAIR ❚❚EMBC approved the budget for 2017. Lovorka Baraç Lauc CROATIA FINANCE COMMITTEE VICE CHAIR Election of officers for 2017 ❚❚EMBC re-elected Gerrit van Meer (NL) as President of EMBC.

➔➔STRATEGIC WORKING PARTY 2016 ❚❚EMBC re-elected Eirikur Steingrimsson (IS) as Vice President and elected Boris Ahmet Ademoğlu TURKEY Turk (SI) as new Vice President. Lucia Banci ITALY ❚❚EMBC appointed Anne Paoletti (FR) new Secretary General of EMBC. Hemma Bauer AUSTRIA ❚❚Conference re-elected Troels Tvedegaard Rasmussen (DK) and Lovorka Baraç Lauc Patrick Cramer GERMANY (HR) as Chair and Vice Chair, respectively, of the EMBC Finance Committee. Josiane Entringer LUXEMBOURG Angela Nieto SPAIN Anne Paoletti FRANCE Mark Palmer UNITED KINGDOM Jeannette Ridder-Numan NETHERLANDS Charalambos Savakis GREECE Eirikur Steingrimsson ICELAND Boris Turk SLOVENIA Gerrit van Meer NETHERLANDS CHAIR Jan Grapentin GERMANY ➔➔See pages 12 for a list of all EMBC Delegates

8 EMBC actions EMBO facts & figures 2016 | embc.embo.org EMBC actions 2016

➔➔FINANCE COMMITTEE ➔➔EMBC MEMBER STATES PERMANENT MEMBERS The following countries are Member States of the European Molecular France Biology Conference (EMBC): Germany ❚❚Austria ❚❚Iceland ❚❚Slovak Republic Italy ❚❚Belgium ❚❚Ireland ❚❚Slovenia Spain ❚❚Croatia ❚❚Israel ❚❚Spain United Kingdom ❚❚Czech Republic ❚❚Italy ❚❚Sweden ❚❚Denmark ❚❚Lithuania1 ❚❚Switzerland ELECTED MEMBERS (2016 – 2019) ❚❚Estonia ❚❚Luxembourg ❚❚Turkey Austria ❚❚Finland ❚❚Malta2 ❚❚United Kingdom Belgium ❚❚France ❚❚Netherlands Croatia 1 joined in May 2016 ❚❚Germany ❚❚Norway Denmark 2 joined in March 2016 ❚❚Greece ❚❚Poland Poland ❚❚Hungary ❚❚Portugal Portugal Netherlands

➔➔For the scale of contributions by the individual EMBC Member States, see page 13

➔➔EMBC Administrator Gitta Bourke [email protected] T +49 6221 8891 117 F +49 6221 8891 202

EMBO facts & figures 2016 | embc.embo.org EMBC actions 9 facts & figures 2016

EMBC Member States 12 – 13

EMBO Council & Committees 14 – 15

EMBO Membership 16 – 19

EMBO Scientific Publications 20 – 23

EMBO Fellowships 24 – 73

EMBO Young Investigators 74 – 81

EMBO Installation Grants 82

EMBO Courses & Workshops 83 – 88

EMBO Women in Science 89 – 93

EMBO Gold Medal 94

EMBO Keynote Lectures 95 – 97

EMBO staff in Heidelberg 98 – 99

EMBO facts & figures 2016 | www.embo.org 11 EMBC Delegates & Advisers

embc.embo.org [email protected]

A President, two Vice Presidents and a Secretary General lead the EMBC, the intergovernmental Prof. Gerrit Van Meer funding body of EMBO. The governments of the member states nominate EMBC Delegates. EMBC President Typically each member state appoints one delegate from a relevant ministry and one scientific Prof. Patrick Cramer adviser. EMBC Secretary General Gitta Bourke EMBC Administrator

Austria Germany Luxembourg Spain Dr. Hemma Bauer Prof. Patrick Cramer Ms Josiane Entringer Dr. Cristina Bauluz Prof. Veronika Sexl Dr. Jan Grapentin Prof. M. Angela Nieto Dr. Andreas Klein Malta Belgium Mr. Marco Abela Sweden Mr Alain Heynen Greece Dr. Joseph Borg Prof. Björn Andersson Prof. Marc van Montagu Prof. Spiros Georgatos Dr. Maria Thuveson Ms Panagiota Katsafana Netherlands Croatia Dr. Jeannette Ridder-Numan Switzerland Dr. Lovorka Baraç Lauc Hungary Prof. Gerrit van Meer Dr. Isabella Beretta Prof. Kreŝimir Paveliç Prof. Làszlò Patthy Prof. Damian Brunner Norway Czech Republic Iceland Prof. Oddmund Bakke Turkey Ms Jana Bystrická Prof. Eiríkur Steingrímsson Dr. Jacob E. Wang Prof. Ahmet Ademoglu Dr. Zdena Palková Ireland Poland United Kingdom Denmark Ms Jennifer Billings Prof. Leszek Kaczmarek Mr Bruce Minty Mr Troels Tvedegaard Rasmussen Dr. Marion Boland Ms Maria Klimkiewicz Dr. Mark Palmer Prof. Jesper Velgaard Olsen Mr Tim Willis Israel Portugal Estonia Dr. Yossi Kalifa Prof. Miguel Castanho Prof. Maia Kivisaar Prof. Joel Sussman Ms Inês Rangel Dr. Toivo Räim Prof. Claudio Sunkel Italy Finland Prof. Lucia Banci Slovak Republic Prof. Johanna Myllyharju Mr Fabio Iannaccone Dr. Silvia Pastoreková Dr. Jarmo Wahlfors Mr Marcel Sládok Lithuania Prof. Ján Turňa France Ms Ausra Sablinskiene Dr. Elena Hoffert Prof. Virginijus Siksnys Slovenia Dr. Anne Paoletti Dr. Tomaz Boh Mr Andrej Ograjensek Prof. Boris Turk

12 EMBC Delegates EMBO facts & figures 2016 | www.embo.org EMBC Member States financial contributions

[email protected]

EMBC Member State 2016 % of total contributions Austria 2.12 Belgium 2.58 Croatia 0.32 Czech Republic 0.94 Denmark 1.67 Estonia 0.10 Finland 1.28 France 14.91 Germany 19.17 Greece 1.36 Hungary 0.59 Iceland 0.06 Ireland 0.98 Israel 1.29 Italy 10.82 Luxembourg 0.18 Netherlands 4.19 Norway 2.60 Poland 2.62 Portugal 1.08 Slovak Republic 0.46 Slovenia 0.24 Spain 7.39 Sweden 2.82 Switzerland 3.55 Turkey 3.02 United Kingdom 13.66 Total 100.00

EMBO facts & figures 2016 | www.embo.org EMBC Member States financial contributions 13 EMBO Council

www.embo.org/about-embo/council [email protected]

The EMBO Council is the governing body of EMBO responsible for ensuring the development of the 2016 organization. The EMBO Council comprises 15 EMBO Members.

EMBO Council members Elected term(s) of office Name Country – Town EMBO Council members Elected term(s) of office Name Country – Town 2011 – 2013, 2014 – 2016 Geneviève Almouzni VICE CHAIR FR-Paris 2011 – 2013, 2014 – 2016 Geneviève Almouzni FR-Paris 2010 – 2012, 2013 – 2015 Pascale Cossart FR-Paris 2016 – 2018 Karen Avraham IL-Tel Aviv 2012 – 2014, 2015 – 2017 Caroline Dean UK-Norwich 2012 – 2014, 2015 – 2017 Caroline Dean UK-Norwich 2014 – 2016 Victor de Lorenzo ES-Madrid 2014 – 2016, 2017 – 2019 Victor de Lorenzo ES-Madrid 2012 – 2014, 2015 – 2017 Denis Duboule CH-Geneva 2012 – 2014, 2015 – 2017 Denis Duboule CH-Geneva 2013 – 2015 Anne Ephrussi DE-Heidelberg 2013 – 2015, 2016 – 2018 Anne Ephrussi DE-Heidelberg 2015 – 2017 Carl-Henrik Heldin SE-Uppsala 2015 – 2017, 2018 – 2020 Carl-Henrik Heldin CHAIR SE-Uppsala 2010 – 2012, 2013 – 2014, Leszek Kaczmarek PL-Warsaw 2014 – 2016, 2017 – 2019 Regine Kahmann DE-Marburg 2015 2015 – 2017, 2018 – 2020 Jürgen Knoblich AT-Vienna 2014 – 2016 Regine Kahmann DE-Marburg 2016 – 2018 László Nagy HU-Debrecen 2015 – 2017 Jürgen Knoblich AT-Vienna 2011 – 2013, 2014 – 2016 Mart Saarma FI-Helsinki 2011 – 2013, 2014 – 2016 Mart Saarma FI-Helsinki 2013 – 2015, 2016 – 2018 Paul Schulze-Lefert DE-Cologne 2013 – 2015 Paul Schulze-Lefert DE-Koeln 2016 – 2018 Titia Sixma NL-Amsterdam 2011 – 2013, 2014 – 2016 Dimitris Thanos GR-Athens 2011 – 2013, 2014 – 2016 Dimitris Thanos GR-Athens 2015 – 2017 Karen Vousden UK-Glasgow 2015 – 2017, 2018 – 2020 Karen Vousden UK-Glasgow 2010 – 2012, 2013 – 2015 Detlef Weigel CHAIR DE-Tuebingen

EMBO Council members are elected for a three-year term of office and may be re-elected for one additional term of office.

Ex officio Council members Maria Leptin Director, EMBO Paul Nurse Secretary General, EMBO

Observers Gerrit van Meer President, EMBC Patrick Cramer Secretary General, EMBC Iain Mattaj Director General, EMBL Jane Langdale CHAIR EMBO Membership Committee Gisou van der Goot CHAIR EMBO Young Investigator Committee Frank Uhlmann CHAIR EMBO Course Committee Sarah Bray CHAIR EMBO Fellowship Committee Reinhard Jahn CHAIR EMBL SAC

14 EMBO Council EMBO facts & figures 2016 | www.embo.org EMBO Committees

www.embo.org/about-embo/committees#publications [email protected]

Members serve on committees to guide core EMBO programmes, activities and publications. The EMBO Council appoints members to serve on committees for a four-year term; committee chairs are appointed 2016 for three years and may serve on the committee beyond the usual four years.

Course Committee Young Investigator Committee EMBO | EMBL Symposia External Auditors 2009 Frank Uhlmann UK CHAIR 2011 Gisou van der Goot CH CHAIR Committee* Central Audit Service Netherlands 2014 Nils Brose DE CHAIR 2013 Christer Betsholtz SE 2010 Maria Leptin DE CHAIR 2014 Javier Cáceres UK 2015 Enrico Coen UK 2008 Iain Mattaj DE, EMBL CHAIR EMBO Audit 2008 Anne Ephrussi DE, EMBL 2013 Christian Lehner CH 2016 Christoph Dehio CH KPMG 2015 Zoi Lygerou GR 2012 Robert Kaptein NL 2013 Anne-Claude Gavin DE, EMBL 2016 Catherine Rabouille NL 2014 Karim Labib UK 2015 Henrik Kaessmann CH Internal Auditor EMBL 2016 Peter Sebo CZ 2015 Laura Machesky UK 2013 Jan Korbel DE, EMBL 2013 Anne Spang CH 2015 Yitzhak Pilpel IL 2015 Michele Labouesse FR Tomasz Smolarek 2016 Jens Stougaard DK 2013 Dietmar Schmucker BE 2011 Frauke Melchior DE 2014 Janet Thornton UK 2013 Maria Sibilia AT 2013 Ramesh Pillai FR, EMBL** 2016 Alfonso Valencia ES 2014 Frank Uhlmann UK 2015 Núria Verdaguer ES * Committee includes Membership Committee EMBO Members and 2014 Arturo Zychlinsky CH 2009 Jane Langdale UK CHAIR Publications Advisory Board* ** external advisers 2015 Johan Auwerx CH 2009 Ivan Dikic DE CHAIR Fellowship Committee 2013 UK 2013 Pietro De Camilli US 2012 Sarah Bray UK CHAIR 2014 Tim Clausen AT 2014 Ari Helenius CH 2013 Andres Aguilera ES 2013 Maria Pia Cosma ES 2011 Robert Kiley UK** 2012 Anna Akhmanova NL 2014 Urs Greber CH 2014 Jo McEntyre UK** 2016 Yehudit Bergmann IL 2014 Edith Heard FR 2014 Tom Misteli US** 2013 Michael Boutros DE 2015 Caroline S. Hill UK 2013 Frank Uhlmann UK 2016 UK 2016 Bernard Malissen FR 2013 Elena Conti DE 2013 Jacques Pouysségur FR FEBS | EMBO Women in Science 2013 Fabrizio d’Adda di Fagagna IT 2015 Maria Rescigno IT Committee* 2012 Liam Dolan UK 2014 Philippe J. Sansonetti FR 2013 Cecilia Arraiano PT 2013 Santiago F. Elena ES 2016 Peter Scheiffele CH 2016 Thomas Boehm DE 2016 Marie-Anne Felix FR 2013 Michel O. Steinmetz CH 2016 Anne-Lise Boerresen-Dale NO** 2016 Nancy Hynes CH 2013 Giulio Superti-Furga AT 2014 Johanna Ivaska FI 2011 Thomas Nyström SE 2016 Markus Wahl DE 2014 Sean Munro UK 2015 Paloma Mas ES 2015 Sabine Werner CH 2014 Gerrit van Meer NL 2014 Eric Miska UK 2014 Kenneth H. Wolfe IE 2016 Isabelle Vernos ES 2016 Mariagrazia Pizza IT 2014 Maciej Zylicz PL 2016 Erin Schumann DE Science Policy Advisory Group* 2013 Luca Scorrano CH 2012 Geneviève Almouzni FR 2015 Michael Sixt AT 2012 Ioannis Economidis BE** 2016 Shahragim Tajbakhsh FR 2013 Anne Ephrussi DE 2011 Nectarios Tavernarakis GR 2012 Toivo Maimets EE** 2016 Dan TawfikIL 2012 Claudio Sunkel PT 2014 Antoine Triller FR 2012 Richard Treisman UK 2013 Pierre Vanderhaeghen BE 2015 Gerrit van Meer NL 2015 Jörg Vogel DE

EMBO facts & figures 2016 | www.embo.org EMBO Committees 15 EMBO Members 2016

www.embo.org/members [email protected]

Scientists who have made outstanding contributions to the life sciences are nominated and elected annually by the membership. More than 1500 of Europe’s leading life scientists are EMBO Members. The membership actively guides the implementation of the many EMBO initiatives offered to scientists by serving on the EMBO Council, Committees and Advisory Editorial Boards.

Name Institute Research interest Adam Antebi Max Planck Institute for Biology of Ageing | Cologne, Biological mechanisms of longevity Germany M. Madan Babu MRC Laboratory of | Cambridge, Regulatory genomics and systems biology United Kingdom Laure Bally-Cuif Institut de Neurobiologie Alfred Fessard | Gif-sur-Yvette, Adult neural stem cell maintenance in vertebrates France and Institut Pasteur | Paris, France Mohamed Bentires-Alj Friedrich Miescher Institute | Basel, Switzerland Breast cancer diversity, resistance and metastasis Michael Brand Technische Universität | Dresden, Germany Regeneration of the vertebrate brain and retina Dana Branzei Istituto FIRC | Milano, Italy DNA replication and chromosome structure integrity Frank Buchholz Technische Universität | Dresden, Germany Genome editing and in medicine Ana I. Caño-Delgado Centre for Research in Agricultural Genomics | Brassinosteroid signaling in stem cell development Barcelona, Spain Jason S. Carroll Cancer Research UK Cambridge Institute | Cambridge, Estrogen Receptor biology in breast cancer United Kingdom Andrew P. Carter MRC Laboratory of Molecular Biology | Cambridge, of the motor protein dynein United Kingdom Agnieszka Chacinska International Institute of Molecular and | Quality control of mitochondrial protein biogenesis Warsaw, Poland Kristina Djinovic-Carugo University of Vienna, Austria and University of Structural biology of the actin-based cytoskeleton Ljubljana, Slovenia Óscar Centro Nacional de Investigaciones Oncológicas (CNIO) | Replicative stress as a driver of cancer and aging Fernández-Capetillo Madrid, Spain and Karolinska Institutet | Stockholm, Sweden Darren Gilmour EMBL | Heidelberg, Germany Collective cell biology of organ formation Ian A. Graham University of York, United Kingdom Plant natural products and seed biology Manajit Hayer-Hartl MPI für Biochemie | Martinsried, Germany Molecular chaperones and Rubisco biogenesis

16 EMBO Members elected in 2016 EMBO facts & figures 2016 | www.embo.org Name Institute Research interest Carl-Philipp Heisenberg Institute of Science and Technology Austria (IST) | Cell and tissue morphogenesis in gastrulation Klosterneuburg, Austria István Katona Institute of Experimental Medicine of the Hungarian Endocannabinoid signaling in the brain Academy of Sciences, Hungary Jan O. Korbel EMBL | Heidelberg, Germany and European From genomic variation to molecular mechanism Bioinformatics Institute | Hinxton | Cambridge, United Kingdom Pekka Lappalainen University of Helsinki, Finland Actin and plasma membrane dynamics Helder Maiato University of Porto, Portugal and Instituto de Biologia Spatial and temporal regulation of Molecular e Cellular (IBMC) | Porto, Portugal Marcos Malumbres Centro Nacional de Investigaciones Oncológicas (CNIO) | Cell division and proliferation in mammals Madrid, Spain Fatima Mechta-Grigoriou Institut Curie | Paris, France and stromal diversity in Maria M. Mota University of Lisbon, Portugal Biology and physiology of malaria Daniel J. Müller ETH Zurich, Switzerland Molecular and cellular biophysics of membranes Eugene Myers MPI für molekulare Zellbiologie und Genetik | Dresden, Image-based systems biology for development Germany Ove Nilsson Swedish University of Agricultural Sciences | Umeå, Regulation of flowering time and tree phenology Sweden Ruth H. Palmer University of Gothenburg, Sweden ALK signaling in Drosophila, mice and human cancer Jane E. Parker MPI für Züchtungsforschung | Köln, Germany Plant innate immunity signalling pathways Matthieu Piel Institut Curie | Paris, France and Institut Gilles de Quantitative, molecular and physical cell biology Gennes | Paris, France Simona Polo Istituto FIRC | Milano, Italy and Università degli Studi | (de)regulation of signaling pathways Milano, Italy Hans-Reimer Rodewald Deutsches Krebsforschungszentrum (DKFZ) | Hematopoietic stem cells and immunology Heidelberg, Germany Claire Rougeulle Université Diderot (Paris 7) | Paris, France Long non-coding RNAs in development and disease Raffaella Santoro University of Zurich, Switzerland Chromatin dynamics in cancer and stem cells Uwe Sauer ETH Zurich, Switzerland Systems biology of Hans R. Schöler MPI für Molekulare Biomedizin | Münster, Germany Programming and reprogramming in mammals Melina Schuh MPI für biophysikalische Chemie | Göttingen, Germany Meiosis in mammalian oocytes Roberto Solano Universidad Autonoma | Madrid, Spain The jasmonate signaling pathway in plants François Spitz Institut Pasteur | Paris, France Genome architecture and regulation Didier Stainier Max-Planck-Institut für Herz- und Lungenforschung | Vertebrate organ development and homeostasis Bad Nauheim, Germany

EMBO facts & figures 2016 | www.embo.org EMBO Members elected in 2016 17 Name Institute Research interest Kate G. Storey University of Dundee, United Kingdom Regulation of neural differentiation Peter ten Dijke University Medical Centre | Leiden, Netherlands TGF-beta family signaling in diseases Pavel Tomancak MPI für molekulare Zellbiologie und Genetik | Dresden, Patterns of in animal development Germany Ian Tomlinson Wellcome Trust Centre for Human | Oxford, Cancer genetics and evolution United Kingdom Jernej Ule University College London, United Kingdom and Francis RNA regulatory networks Crick Institute | London, United Kingdom Antonella Viola Università di Padova, Italy and Università degli Studi | Immune Milano, Italy Douglas J. Winton , United Kingdom Functional properties of intestinal stem cells Gulnara Yusupova Institute of Genetics and Molecular and Cellular Biology Mechanism of protein biosynthesis at the ribosome (IGBMC) | Illkirch, France Xiaodong Zhang Imperial College | London, United Kingdom Structures and mechanisms of macromolecular machines Juleen R. Zierath Karolinska Institutet | Stockholm, Sweden Skeletal muscle glucose metabolism and development

18 EMBO Members elected in 2016 EMBO facts & figures 2016 | www.embo.org EMBO Associate Members 2016

www.embo.org/members [email protected]

Scientists who have made outstanding contributions to the life sciences, and reside in countries other than the member states, are nominated and elected annually by the membership. 136 of the world’s leading life scientists are EMBO Associate Members.

Name Institute Research interest George Fu Gao Chinese Academy of Sciences | Beijing, China and Protein interactions in virus entry and immunity Chinese Center for Disease Control and Prevention (China CDC) | Beijing, China Hiroshi Hamada RIKEN Center for Developmental Biology | Kobe, Japan Origin of body asymmetries in the mouse embryo Marc W. Kirschner Harvard Medical School | Boston, United States regulation, mass spectrometry Timothy J. Mitchison Harvard Medical School | Boston, United States Fundamental mechanisms of cell organization and movement Huck-Hui Ng Genome Institute | Singapore Self-renewal and differentiation of stem cells Virginijus Siksnys Vilnius University, Lithuania Mechanisms of antiviral defense in prokaryotes Hong Wu Peking University | Beijing, China PTEN controlled signaling pathway and tumorigenesis Harvard University | Cambridge, United States Advanced imaging of cellular structures

EMBO facts & figures 2016 | www.embo.org EMBO Associate Members elected in 2016 19 EMBO Scientific Publications

www.embo.org/scientific-publications

Bernd Pulverer Head Thomas Lemberger The EMBO Journal Deputy Head

The EMBO Journal has been EMBO’s flagship publication for over 30 years. With a scope that spans all areas of molecular biology, the journal has an international reputation for quality and originality.

Advisory Editorial Board 2016 | The EMBO Journal emboj.embopress.org | [email protected]

Reuven Agami Susan M Gasser Thomas Kunkel Nikolaus Pfanner Gerrit van Meer * new role at EMBO in Andrés Aguilera Holger Gerhardt Karim Labib Jonathon Pines Isabelle Vernos 2016 Dario Alessi Pierre Gönczy Achim Leutz Olaf Pongs Jörg Vogel Geneviève Almouzni Magdalena Götz Joachim Lingner Anthony Pugsley Olivier Voinnet Johan Auwerx Ingrid Grummt Bernard Malissen Peter J Ratcliffe Karen Vousden David Barford Crisanto Gutierrez Javier Martinez Gabriel Waksman Denise P Barlow Christian Haass Joan Massagué Anne Ridley Michael Way Facundo Batista Michael N Hall Iain W Mattaj Marina Rodnina Stephen C West David Baulcombe Randy Hall Marjori Matzke David Ron Eric Westhof Anton J Berns Stephen C Harrison Ira Mellman Helen R Saibil Dale Wigley Cedric Blanpain F Ulrich Hartl Marco Milán Philippe J Sansonetti Alfred Wittinghofer Chris Bowler Carl-Philipp Heisenberg Sean Morrison Dirk Schübeler Dieter H Wolf Erik Boye Ari H Helenius Jorge Moscat Paul Schulze-Lefert Richard Wood Bernd Bukau Kristian Helin Shmuel Muallem Luca Scorrano Jeff Wrana Javier Cáceres Regine Hengge Sean Munro Bertrand Séraphin Pico Caroni Nobutaka Hirokawa Kiyoshi Nagai Michael Sheetz Chief Editor Christine E Clayton Mark Hochstrasser Christof Niehrs David J Sherratt Bernd Pulverer M Angela Nieto Benny Shilo Daniela Corda Tony Hunter Bernd Nilius Roberto Sitia Editors Patrick Cramer Ed Hurt Eisuke Nishida Austin Smith David del Alamo* Pietro V De Camilli Nancy E Hynes Poul Nissen Harald Stenmark Karin Dumstrei Bart De Strooper Elisa Izaurralde Paul Nurse Thomas Surrey Ieva Gailite Ivan Dikic Stephen P Jackson Andre Nussenzweig Masatoshi Takeichi Daniel Klimmeck Vishva Dixit Reinhard Jahn Moshe Oren Sharon Tooze Andrea Leibfried Giulio F Draetta Roland Kanaar Tom Owen-Hughes Laszlo Tora Anne Nielsen Martin Eilers V. Narry Kim Marcus E Peter Hiroki Ueda Hartmut Vodermaier Jeff Errington Rüdiger Klein Matthias Peter Frank Uhlmann Reinhard Fässler Guido Kroemer Daan van Aalten

20 EMBO Scientific Publications EMBO facts & figures 2016 | www.embo.org EMBO Scientific Publications

EMBO reports

EMBO reports publishes scientific research in all areas of molecular biology, as well as expert reviews from leading researchers and editorial content that offers insight into the broader issues affecting science and society.

Advisory Editorial Board 2016 | EMBO reports embor.embopress.org | [email protected]

Reuven Agami Jonathan Frampton Trevor Lithgow Joseph Puglisi Gabriel Waksman Acting Chief Editor Andrés Aguilera Mike Gale Manyuan Long Michael Rape David Wallach Bernd Pulverer Dario Alessi Holger Gerhardt Jiri Lukas Peter J Ratcliffe Ming-Bo Wang Manuela Baccarini Cayetano Gonzalez Bernard Malissen Felix Rey Yoshi Watanabe Editors Fredrik Bäckhed Lawrence Gostin Michael Malim Hans-Jörg Rheinberger Michael Way Achim Breiling Vytas Bankaitis Magdalena Götz Rob Martienssen Anne Ridley Beverley Wendland Holger Breithaupt Facundo Batista Jean Gruenberg Javier Martinez Arie Rip Stephen C West Samuel Caddick* David Baulcombe Leonard Guarente René Medema Marina Rodnina Jerry Workman Barbara Pauly* Roger Beachy Crisanto Gutierrez Pascal Meier Meng-Chao Yao Martina Rembold Peter B Becker Ilkka Hanski Ira Mellman Eytan Ruppin Seppo Ylä-Herttuala Esther Schnapp David Bentley Stephen C Harrison Marco Milán Helen R Saibil Hong Zhang Anton J Berns Christian Hardtke Randall Moon Naruya Saitou Jianzhi ‘George’ Zhang Lutz Bornmann Daniel Hartl Vamsi Mootha Philippe J Sansonetti * left EMBO in 2016 Michel Bouvier Bassem Hassan Sean Morrison Claus Scheidereit Special Advisors Pico Caroni Volker Haucke Jorge Moscat Ueli Schibler Art Caplan Timothy Caulfield Yuehui He Andrea Musacchio Roded Sharan Lars Schaade James J Collins Kristian Helin László Nagy Benny Shilo Jeremy Sugarman Barbara Conradt Regine Hengge M Angela Nieto Haruhiko Siomi Hanna-Marja Voipio Elizabeth Craig Tony Hunter Bernd Nilius Titia Sixma Axel Wolff Beverly Davidson Elisa Izaurralde Poul Nissen Bruce Spiegelman Raymond Zilinskas Mario de Bono Thomas Nyström Nicholas Steneck Gianni Del Sal Moshe Oren Mark Stoneking Claude Desplan Batsheva Kerem Duanqing Pei Michael Sussman Ivan Dikic Daniel Klionsky Norbert Perrimon Jesper Svejstrup Catherine Drennan Karim Labib Matthias Peter Nektarios Tavernarakis Daniel Durocher Thomas Langer Stefano Piccolo Dan Tawfik Zvulun Elazar Roland Lill Jonathon Pines David Tollervey Jeff Errington Joachim Lingner Kathrin Plath Amy Wagers

EMBO facts & figures 2016 | www.embo.org EMBO Scientific Publications 21 EMBO Scientific Publications

Molecular Systems Biology

Molecular Systems Biology is a peer-reviewed, online open access journal that publishes high-quality research in the fields of systems biology, synthetic biology and systems medicine.

Advisory Editorial Board 2016 | Molecular Systems Biology msb.embopress.org | [email protected]

Ido Amit Galit Lahav Jan Skotheim Johan Auwerx Rune Linding Christina Smolke Gary Bader Andrew Millar Michael Snyder Philippe Bastiaens Vamsi Mootha Peter Sorger Ewan Birney Felix Naef Igor Stagljar Michael Boutros Jeremy Nicholson Alexander Stark Markus Covert Garry Nolan Lars Steinmetz Patrick Cramer Béla Novák Amos Tanay Ileana Cristea Duncan Odom Marc Vidal Roland Eils Alexander van Oudenaarden Albertha (Marian) Walhout Jan Ellenberg Bernhard Palsson Jun Wang Michael Elowitz Lucas Pelkmans Hans V. Westerhoff James Ferrell Norbert Perrimon Lingchong You Eileen Furlong Ana Pombo Marino Zerial Anne-Claude Gavin Joshua Rabinowitz Ronald Germain Nikolaus Rajewsky Senior Editors Mark Gerstein Rama Ranganathan Ruedi Aebersold Anne-Claude Gingras Aviv Regev Peer Bork Alexander Hoffmann Frederick (Fritz) Roth George Church Frank Holstege Eytan Ruppin Leroy Hood Laurence D. Hurst Uwe Sauer Edison Liu Terence Hwa Eric Schadt Trey Ideker Dirk Schübeler Chief Editor Dirk Inzé Luis Serrano Thomas Lemberger Boris Kholodenko Lucy Shapiro Hiroaki Kitano James Sharpe Editor Jan Korbel Benny Shilo Maria Polychronidou Nevan J. Krogan Pamela Silver

22 EMBO Scientific Publications EMBO facts & figures 2016 | www.embo.org EMBO Scientific Publications

EMBO Molecular Medicine

EMBO EMBO Molecular Medicine is a peer-reviewed, online open access journal dedicated to research at the Molecular interface between clinical research and basic biology. Medicine

Advisory Editorial Board 2016 | EMBO Molecular Medicine embomolmed.embopress.org | [email protected]

Adriano Aguzzi Nancy E. Hynes Deepak Srivastava Chief Editor Alberto Auricchio Alain Israel Anu Suomalainen-Wartiovaara Stefanie Dimmeler* Barbara B. Kahn Giulio Superti-Furga Stylianos Antonarakis Cynthia Kenyon Elaine I. Tuomanen Editors Alan Ashworth Robert S. Kerbel Axel Ullrich Roberto Buccione Karen B. Avraham Jean-Pierre Kinet Inder M. Verma Céline Carret Andrea Ballabio Andreas E. Kulozik Simon Wain-Hobson Yann Barrandon Guido Kroemer Gerd Walz Anton J. Berns Claude Libert Fiona Watt * left in 2016 Cédric Blanpain Christian Weber Clara D. Bloomfield Matthias Nahrendorf Lars Zender Carlos Caldas Pierluigi Nicotera Vivian Cheung Bernd Nilius Senior Editors Kenneth Chien Eric N. Olson Dario Alessi Hans Clevers Stephen O’Rahilly Giulio Cossu Ralph DeBerardinis Albert Osterhaus Uta Francke Elisabetta Dejana Manolis Pasparakis Fred H. Gage Sven Diederichs Christine Petit Matthias Hentze Oliver Eickelberg Kornelia Polyak Gökhan S. Hotamişlıgil Martin Eilers Joan Massagué Marc Feldmann Peter J. Ratcliffe Philippe Sansonetti Alain Fischer Gideon Rechavi Bart de Strooper Philippe Froguel Paola Ricciardi-Castagnoli Gerardo Gamba Nadia Rosenthal Martin Gleave Nicholas J. Schork Christian Haass Yosef Shiloh Carl-Henrik Heldin Gerald Shulman Jan Hoeijmakers Bruce Spiegelman

EMBO facts & figures 2016 | www.embo.org EMBO Scientific Publications 23 EMBO Fellowships

www.embo.org/funding-awards/fellowships [email protected]

Renowned for its strict attention to scientific excellence, the EMBO Fellowship Programme David del Alamo has supported thousands of talented young scientists since its launch in the 1960s. EMBO Programme Manager Fellowships support postdoctoral and predoctoral research visits of varying duration to laboratories throughout the EMBC Member States and internationally.

EMBO Long-Term Fellowships ➔➔

EMBO Long-Term Fellowships: Statistics Applications and awards 1977– 2016 Year Applications Awards Success rate % Year Applications Awards Success rate % 2016 1561 170 11 1993 739 199 27 2015 1549 252 16 1992 626 142 23 2014 1648 247 15 1991 571 139 24 2013 1645 185 11 1990 526 123 23 2012 1555 247 16 1989 460 118 26 2011 1633 268 16 1988 455 141 31 2010 1668 275 16 1987 383 120 31 2009 1332 258 19 1986 333 90 27 2008 1218 215 18 1985 340 92 27 2007 1288 212 16 1984 305 112 37 2006 1232 222 18 1983 294 103 35 2005 1236 198 16 1982 276 91 33 2004 1137 163 14 1981 274 111 41 2003 1080 164 15 1980 242 108 45 2002 789 178 23 1979 254 101 40 2001 645 147 23 1978 235 101 43 2000 707 155 22 1977 236 94 40 1999 830 170 20 1998 790 144 18 1997 831 185 22 1996 898 160 18 1995 877 147 17 1994 806 176 22

24 EMBO Long-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships: Statistics Applications and awards 2012 – 2016 Country from* Applications % of total Awards % of total Success rate % Austria 94 1 20 2 21 Belgium 152 2 24 2 16 Croatia 50 1 7 <1 14 Czech Republic 71 1 6 1 8 Denmark 39 0 4 0 10 Estonia 23 <1 2 <1 9 Finland 80 1 8 1 10 France 897 11 112 10 12 Germany 791 10 174 16 22 Greece 104 1 20 2 19 Hungary 78 1 4 <1 5 Iceland 4 <1 2 <1 50 Ireland 57 1 5 <1 9 Israel 438 6 91 8 21 Italy 571 7 85 8 15 Luxembourg 5 <1 2 <1 40 Netherlands 293 4 52 5 18 Norway 8 <1 1 <1 13 Poland 191 2 29 3 15 Portugal 246 3 29 3 12 Slovak Republic 41 <1 4 <1 10 Slovenia 20 <1 1 0 5 Spain 1030 13 84 8 8 Sweden 147 2 14 1 10 Switzerland 91 1 17 2 19 Turkey 76 1 14 1 18 United Kingdom 220 3 39 4 18 Eastern Europe 185 2 30 3 16 USA/Canada 384 5 80 7 21 Others 1572 20 141 13 9 Total 7958 100 1101 100 14

* “Country from” refers to nationality

EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships 25 EMBO Long-Term Fellowships awarded in 2016 | EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project Mair, Austrian University of Vienna, Dominique , Exploring the complexity of complexes – Andrea Austria Bergmann United States how closely related bHLH factors drive differential gene expression in stomatal development of Arabidopsis and Brachypodium Wculek, Austrian Institute | David Sancho Centro Nacional Targeting mitochondrial biology in Stefanie London, United Kingdom Madrid de Investigaciones dendritic cells in homeostasis and cancer Cardiovasculares (CNIC) | Madrid, Spain Beaufay, Belgian Katholieke Universiteit | Ursula Jakob University of Michigan | Bacterial polyphosphate homeostasis François Leuven, Belgium Ann Arbor, United States and its role in persister cell formation Brouwers, Belgian Katholieke Universiteit | I. Sadaf Farooqi University of Cambridge, Dissecting the role of Serotonin 2c Bas Leuven, Belgium United Kingdom receptor (5-HT2CR) mediated signaling in human energy homeostasis Gryseels, Belgian University of Antwerp, Michael Worobey University of Arizona | Unveiling the early dynamics of the Sophie Belgium Tucson, United States HIV-1 epidemic using archival viral genomes Ronneau, Belgian University of Namur, Sophie Helaine Imperial College | London, Molecular mechanism of persister cell Séverin Belgium United Kingdom awakening in Salmonella Burton, British , Tom Muir Princeton University, Sculpting chromatin architecture in live Antony United Kingdom United States cells using protein chemistry Horton, British University of Manchester, Janine Erler University of Copenhagen, Investigation into the functional role of Edward United Kingdom Denmark non-canonical adhesome components in cancer cell invasion and metastasis Malinsky, British | Walter Salzburger University of Basel, Molecular basis of convergent evolution Milan University of Cambridge, Switzerland between cichlid fishes of lakes Malawi United Kingdom and Tanganyika Minamino, British University of Tokyo, Japan Frank Uhlmann | Reconstitution of establishment of sister Masashi London, United Kingdom chromatid cohesion Morris, British Institute of Cancer Heinrich Jasper Buck Institute for Decoding the role of Ca2+ oscillations in Otto Research | London, Research on Aging | Intestinal Stem Cell activity and fate United Kingdom Novato, United States Puleston, British , Erika Pearce MPI für Immunbiologie Functions of the polyamine synthesis Daniel United Kingdom und Epigenetik | Freiburg, pathway in T cell biology Germany Richards, British University of Bristol, Lena Uppsala University, Real-time characterisation of VEGF Mark United Kingdom Claesson-Welsh Sweden induced vascular permeability Robson, British Wellcome Trust Centre | Stefan Mundlos Max Planck Institute Using human disease and genome Michael Edinburgh, United for Molecular Genetics | engineering to dissect dynamic genome Kingdom Berlin, Germany organisation from the nuclear lamina in vivo during development

26 EMBO Long-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships awarded in 2016 | EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project Cvetesic, Croatian University of Zagreb, Boris Lenhard Imperial College | London, Transcription start site selection at Nevena Croatia United Kingdom core promoters and its functional consequences in embryonic development Lisica, Croatian Technische Universität | Guillaume University College London, The role of mechanics during cell division Ana Dresden, Germany Charras United Kingdom in monolayers Husnik, Czech University of South Patrick Keeling University of British The functional role of endosymbiotic Filip Bohemia | Ceske Columbia | Vancouver, gene transfer in organelle evolution Budejovice, Czech Canada Republic Boekhout, Dutch Netherlands Cancer Scott Keeney Memorial Sloan-Kettering Shedding light on meiotic recombination Michiel Institute | Amsterdam, Cancer Center | New York, Netherlands United States Hendriks, Dutch Friedrich Miescher Rickard Sandberg Karolinska Institutet | Exploring the temporal dynamics Gerardus Johannes Institute | Basel, Stockholm, Sweden of autosomal random monoallelic Switzerland expression Hendriks, Dutch University Medical Michael Lund University of Copenhagen, Characterization of crosstalk between Ivo Centre | Nielsen Denmark SUMOylation and poly(ADP-ribosyl) Leiden, Netherlands ation in health and disease through mass spectrometry-based proteomics Hibbel, Dutch MPI für molekulare Karsten Weis ETH Zurich, Switzerland In vivo analysis of protein import through Anneke Zellbiologie und Genetik | the nuclear pore complex by single- Dresden, Germany molecule fluorescence microscopy Ietswaart, Dutch John Innes Centre | L. Stirling Harvard Medical School | Quantitative dissection of chromatin Robert Norwich, United Kingdom Churchman Boston, United States regulator functioning in human transcriptional networks Klein Herenbrink, Dutch Monash University | Ulrik Gether University of Copenhagen, Single molecule tracking of the Carmen Parkville, Australia Denmark dopamine transporter Koorman, Dutch , Andrea General Deciphering the polarity:proliferation Thijs Netherlands McClatchey Hospital | Boston, interface United States Schirris, Dutch Radboud University | Edmund Kunji MRC Mitochondrial Elucidating the role of mitochondrial Tom Nijmegen, Netherlands Biology Unit | Cambridge, transport proteins in drug toxicity United Kingdom Slaats, Dutch University Medical Bernhard University of Cologne, Cilia proteins act as genome Gisela Centre (UMC) | Utrecht, Schermer Germany maintenance factors that protect from Netherlands renal fibrosis Van Gestel, Dutch University of Lausanne, Andreas Wagner University of Zurich, The evolvability of bacterial Jordi Switzerland Switzerland multicellularity Van Gisbergen, Dutch University of Sophie G. Martin University of Lausanne, Architecture and stabilization Peter Massachusetts | Amherst, Switzerland mechanisms of the actin fusion focus United States during yeast mating

EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships 27 EMBO Long-Term Fellowships awarded in 2016 | EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project Jolma, Finnish Karolinska Institutet | Timothy Hughes University of Toronto, Analysis of cooperativity and specificity Arttu Stockholm, Sweden Canada of heterodimeric RNA-binding protein complexes Rosenthal, Finnish MPI für terrestrische David Weitz Harvard University | Automated continuous evolution with Raoul Mikrobiologie | Marburg, Cambridge, United States reverse transcriptase Germany Anne, French Université Paris-Saclay | Hardtke Christian University of Lausanne, Characterization of CLE26 signaling Pauline Gif-sur-Yvette, France Switzerland pathway in the control of phloem specification in Arabidopsis thaliana Benechet, French University of Connecticut | Matteo Iannacone San Raffaele Institute | Molecular determinants of hepatic Alexandre Farmington, United States Milano, Italy HBV-specific effector CD8+ T cell intrasinusoidal crawling Brunet, French EMBL | Heidelberg, Nicole King University of California | The pre-metazoan origins of animal cell Thibaut Germany Berkeley, United States contractility Cazettes, French Albert Einstein College Zachary F. Mainen Champalimaud Centre Neuromodulation of cortical Fanny of Medicine | New York, for the Unknown | Lisbon, representations of policy uncertainty United States Portugal Dang, French École Polytechnique | Richard Assoian University of Pennsylvania | Extracellular matrix stiffness regulates Irene Palaiseau, France Philadelphia, Rac activity to control cell proliferation United States Godfrey, French Francis Crick Institute | Sander Van Den Utrecht University, Examining the interplay between cell Molly London, United Kingdom Heuvel Netherlands cycle regulators and chromatin factors in coordinating cell cycle exit and differentiation Guey, French Université Claude Bernard Andrea Ablasser Swiss Federal Institute of Dissecting the crosstalk between cell Baptiste Lyon 1 | Lyon, France Technology | Lausanne, proliferation and innate immune Switzerland signaling Jean, French Institut de Biologie Jan Löwe MRC Laboratory of Structure and function of the Nicolas Structurale | Grenoble, Molecular Biology | transmembrane DNA motor protein FtsK France Cambridge, United Kingdom Lamoliatte, French Université | Montreal, Matthias Trost Newcastle University, Characterizing the role of ISGylation in Frederic Canada United Kingdom bacterial infection of macrophages Nassour, French Université Lille 2 | Lille, Jan Karlseder Salk Institute | La Jolla, Escape from proliferation crisis as a Joe France United States multistep process involving cell death resistance and telomere maintenance Pierron, French Université Claude Bernard Pierre Gönczy Swiss Federal Institute of Uncovering mechanisms of centriole Marie Lyon 1 | Villeurbanne, Technology | Lausanne, elimination during C. elegans oogenesis France Switzerland Ruffault, French Université Paris-Saclay | Carmen Max-Delbrück-Centrum | Genetic and functional dissection of the Pierre-Louis Gif-sur-Yvette, France Birchmeier Berlin, Germany nucleus of the solitary tract (NTS) circuits controlling vocalization and breathing

28 EMBO Long-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships awarded in 2016 | EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project Theret, French Université Claude Bernard Fabio Rossi University of British Signaling pathways controlling fibro/ Marine Lyon 1 | Villeurbanne, Columbia | Vancouver, adipogenic progenitors differentiation France Canada into fibrogenic cells during skeletal muscle regeneration Vincent, French University of Bordeaux, Elisabeth Johns Hopkins University | Deciphering the uni- and multiquantal Philippe France Glowatzki Baltimore, United States release mechanism of adult auditory inner hair cell synapses by expressing the VGLUT1 or VGLUT2 (vesicular glutamate transporter) instead of the native VGLUT3 isoform Webster, French California Institute of Melina Schuh MPI für biophysikalische Dynamics of RNA transcript regulation Alexandre Technology | Pasadena, Chemie | Göttingen, during meiosis in mammalian oocytes United States Germany Zoued, French Laboratoire d'Ingénierie Matthew K. Harvard Medical School | Interrogating and host Abdelrahim des Systèmes Waldor Boston, United States cell surfaces during infection with Macromoléculaires (LISM) | quantitative proteomics Marseille, France Baumgarten, German King Abdullah University Artur Scherf Institut Pasteur | Paris, The Plasmodium epitranscriptome: Sebastian of Science & Technology | France deciphering the role of RNA Thuwal, Saudi Arabia modifications in human malaria parasite virulence Böttinger, German Universität Freiburg, Hans C. Clevers Hubrecht Institute | Exploiting human lung organoids to Lena Germany Utrecht, Netherlands understand alveolar regeneration and cell-specific antiviral strategies Busche, German Technische Universität | Bradley Hyman Massachusetts General Untangling the contributions of Marc Aurel München, Germany Hospital (MGH) | Amyloid-beta and Tau to neural circuit Charlestown, dysfunction in Alzheimer´s disease in United States vivo Dietlein, German University of Cologne, Elizier Van Allen Dana-Farber Cancer A platform to identify synergistic Felix Germany Institute | Boston, interactions between small-molecule United States inhibitors and immune checkpoint blockade in cancer Flock, German MRC Laboratory of Gebhard Schertler Paul Scherrer Institut | Unravelling the molecular details of Tilman Molecular Biology | Villigen, Switzerland ligand-biased signalling in GPCRs using Cambridge, United integrative multi-scale structural biology Kingdom Gaub, German University of California | Daniel J. Müller ETH Zurich, Switzerland From force to function: characterization Benjamin Berkeley, United States and application of mechanosensitive Piezo receptors Goldeck, German Universität Bonn, Javier Martinez Max F. Perutz Laboratories | The Role of the RNA 3'-Terminal Marion Germany University of Vienna, Phosphate Cyclase RTCD1 in innate Austria immunity and in the unfolded protein response

EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships 29 EMBO Long-Term Fellowships awarded in 2016 | EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project Graeber, German Royal Holloway University Claudia Köhler Swedish University of How clones memorize past Kai of London | Egham, Agricultural Sciences | environments – molecular mechanisms United Kingdom Uppsala, Sweden regulating epigenetic inheritance of temperature experience in vegetatively propagating plants Harms, German Biozentrum | University of Kenn Gerdes University of Copenhagen, The enemy of my enemy is my friend: Alexander Basel, Switzerland Denmark using phages to reveal new weak spots of bacterial persisters Hauser, German MPI für Biochemie | Paola Picotti ETH Zurich, Switzerland Next-generation functional proteomics – Thomas Martinsried, Germany measuring protein functional states in entire cellular pathways using a structural proteomics approach Kleele, German Technische Universität | Suliana Manley Swiss Federal Institute of Understanding the physical and Tatjana München, Germany Technology | Lausanne, physiological principles of mitochondrial Switzerland fission using live-cell super-resolution microscopy Kochanowski, German ETH Zurich, Switzerland Steven Altschuler University of California Identifying the metabolic and regulatory Karl San Francisco, determinants of drug tolerance in non- United States small-cell lung cancer models Kosche, German New York University Botond Roska Friedrich Miescher Detection of visual motion in the cortex Georg (NYU) | Institute | Basel, New York, United States Switzerland Malinovska, German MPI für molekulare Paola Picotti ETH Zurich, Switzerland Systematic analysis of cellular responses Liliana Zellbiologie und Genetik | to protein aggregation in the context of Dresden, Germany neurodegenerative diseases Mevissen, German MRC Laboratory of Johannes Walter Harvard Medical School | Biochemical analysis of transcription- Tycho Molecular Biology | Boston, United States coupled DNA interstrand cross-link repair Cambridge, United Kingdom Morgner, German Max Planck Institute Jacco Van Hubrecht Institute | The dynamics of cell-matrix interactions Jessica for Biology of Ageing | Rheenen Utrecht, Netherlands during metastasis formation and Cologne, Germany reactivation Müllner, German MPI für Neurobiologie | Botond Roska Friedrich Miescher Circuit analysis of thalamic visual Fiona Martinsried, Germany Institute | Basel, processing and its modulation by long- Switzerland range projections Saur, German Australian National Paul MPI für Targeting of host proteins by unrelated Isabel University | Canberra, Schulze-Lefert Züchtungsforschung | pathogen effectors and their surveillance Australia Köln, Germany by allelic immune receptors Sawyer, German MPI für evolutionäre Ludovic Orlando University of Copenhagen, Conservation genomics of endangered Susanna Anthropologie | Leipzig, Denmark indigenous European horse breeds Germany

30 EMBO Long-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships awarded in 2016 | EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project Schmiedel, German Charité – Ben Lehner Centro de Regulación Comprehensive analysis of expression- Jörn Universitätsmedizin | Genómica (CRG) | fitness functions (EFFs) Berlin, Germany Barcelona, Spain Schmolka, German University of Lisbon, Tuncay Baubec University of Zurich, Comprehensive analysis of genomic Nina Portugal Switzerland binding preference and functional role of Lsh Schroer, German University of Münster, Siewert-Jan University of Groningen, Dynamics and thermodynamics of actin Carsten Germany Marrink Netherlands filament formation Sladitschek, German EMBL | Heidelberg, Stefano Piccolo Università di Padova, Italy Elucidating the mechanism of Hanna Germany mechanotransduction through YAP/TAZ Von Appen, German EMBL | Heidelberg, Adam Frost University of California | The role of ESCRT-III proteins in nuclear Alexander Germany San Diego, United States envelope reformation Zarkada, Greek University of Helsinki, Anne Eichmann School of Neuropilin 1 as a novel target to inhibit Georgia Finland Medicine | New Haven, ocular neovascularization United States Lyons, Irish Université Paris Descartes | Jason Rihel University College London, Investigating the neural circuit basis Declan Paris, France United Kingdom of sleep disturbance-induced cognitive deficits Schwartz, Irish Universitätsklinikum | Padraic Fallon Trinity College | Dublin, Checkpoint-control of adaptive Christian Erlangen, Germany Ireland immunity by innate lymphoid cells Alcolombri, Israeli Weizmann Institute of Roman Stocker ETH Zurich, Switzerland Unraveling the microscale mechanisms Uria Science | Rehovot, Israel driving particle degradation in the ocean Arzi, Israeli Weizmann Institute of Tristan University of Cambridge, A neural fingerprint of consciousness: Anat Science | Rehovot, Israel Bekinschtein United Kingdom brain processing in the absence of conscious awareness Bar-On, Israeli The Hebrew University | Michel Rockefeller University | Profiling HIV-1 integration sites selection Yotam Jerusalem, Israel Nussenzweig New York, United States and ist association with viral productivity Biran, Israeli Weizmann Institute of Jean-Laurent Rockefeller University | Search for novel single-gene inborn Anat Science | Rehovot, Israel Casanova New York, United States errors of immunity underlying herpes simplex encephalitis of childhood Davidi, Israeli Weizmann Institute of Sabeeha University of California | Biochemical and molecular genetic Lital Science | Rehovot, Israel Merchant Los Angeles, United States analysis of iron homeostasis in Chlamydomonas Drayman, Israeli Weizmann Institute of Savas Tay University of Chicago, Characterizing the innate immune Nir Science | Rehovot, Israel United States response to Influenza virus infection in single cells Galili, Israeli MPI für Neurobiologie | Gregory Jefferis MRC Laboratory of Sexually dimorphic neuronal circuits Dana Martinsried, Germany Molecular Biology | underlying social behaviours in Cambridge, Drosophila United Kingdom

EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships 31 EMBO Long-Term Fellowships awarded in 2016 | EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project Geula, Israeli Weizmann Institute of Sean Morrison University of Texas Deciphering the mechanisms that Shay Science | Rehovot, Israel Southwestern Medical regulate hematopoietic stem cell aging Center | Dallas, United States Gur-Cohen, Israeli Weizmann Institute of Rockefeller University | Dissecting the spatiotemporal crosstalk Shiri Science | Rehovot, Israel New York, United States between hair follicle stem cells and the vascular capillary network Keren, Israeli Weizmann Institute of Michael Angelo Stanford University, Studying the tumor immune Leeat Science | Rehovot, Israel United States microenvironment in breast cancer using a novel multiplexed imaging platform Ordan, Israeli Weizmann Institute of Jean-Paul Vincent Francis Crick Institute | The role of developmental signals in Eliahu Science | Rehovot, Israel London, United Kingdom tissue-growth control Shipony, Israeli Weizmann Institute of William Greenleaf Stanford University, Understanding enhancer regulated gene Zohar Science | Rehovot, Israel United States response in ricin sensitivity Zviran, Israeli Weizmann Institute of Dan Landau Genome Center | New Algorithmically-driven cancer therapy Asaf Science | Rehovot, Israel York, United States to overcome cancer evolution and resistance Allegretti, Italian MPI für Biophysik | Martin Beck EMBL | Heidelberg, High-resolution in situ structural Matteo Frankfurt, Germany Germany investigation of nuclear pore complex assembly intermediates populated by depletion of newly synthesized nucleoporins Arbore, Italian King's College | London, Paolo Dellabona San Raffaele Institute Investigating the effects of immunogenic Giuseppina United Kingdom (HSR/TIGET) | Milano, Italy chemoradiation in shaping the immune landscape of esophageal cancers Bonavita, Italian Istituto Clinico Humanitas | Santiago Zelenay University of Manchester, Mechanisms of immune evasion in Eduardo Rozzano, Italy United Kingdom melanoma Caviglia, Italian University of Zurich, Elke Ober University of Copenhagen, Liver goes live: from migrating Sara Switzerland Denmark progenitors to functional epithelial units D'Amato, Italian Centro Nacional Kristy Red-Horse Stanford University, Dach1 regulates endothelial responses to Gaetano de Investigaciones United States hemodynamic forces to stimulate artery Cardiovasculares (CNIC) | growth and modulate vascular disease Madrid, Spain De Franceschi, Italian University | Turku, Finland Patricia Bassereau Institut Curie | Paris, A novel model for ESCRT-III mediated Nicola France membrane fission Inverso, Italian San Raffaele Institute/ Hellmut Augustin Deutsches Defining a paradigm for hepatocellular Donato DIBIT | Milano, Italy Krebsforschungszentrum carcinoma (HCC) cell microvascular (DKFZ) | Heidelberg, invasion Germany Legnini, Italian Università 'La Sapienza' | Nikolaus Max-Delbrück-Centrum | Functional links between splicing and Ivano Roma, Italy Rajewsky Berlin, Germany translation of circular RNAs and mRNAs in neural systems and single cells

32 EMBO Long-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships awarded in 2016 | EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project Magrinelli, Italian Institut de Biologie Denis Jabaudon University of Geneva, Using single-cell transcriptomic Elia Valrose | Nice, France Switzerland approaches to unravel the functional diversity of cortical areas Petrungaro, Italian University of Cologne, Benoit Kornmann ETH Zurich, Switzerland Tracing lipids: How do organelles Carmelina Germany maintain their membranes? Sannino, Italian San Raffaele Institute/ Jeffrey Brodsky University of Pittsburgh, Protein quality control in cancer: Sara DIBIT | Milano, Italy United States ER-associated degradation and breast cancer subtypes Tschurtschenthaler, Italian University of Cambridge, Dieter Saur Technische Universität | Causes and consequences of Markus United Kingdom München, Germany in subtypes of sporadic intestinal cancer Zanini, Italian MPI für Stephen Quake Stanford University, Coevolutionary dynamics between virus, Fabio Entwicklungsbiologie | United States target cells, and immune system during Tübingen, Germany dengue infection Zauri, Italian University of Oxford, Giulio CeMM | Vienna, Austria Systematic identification of the cellular Melania United Kingdom Superti-Furga network of nucleotide metabolism Kolodziejczyk, Polish Sanger Institute | Eran Elinav Weizmann Institute of Deciphering cell–cell and cell– Aleksandra Cambridge, Science | Rehovot, Israel microbiome interactions of innate United Kingdom lymphoid cells at the single cell level Nowak, Polish , Jürgen Knoblich IMBA | Vienna, Austria Role of brain vasculature in cerebral Jakub United Kingdom organoid model of human cortical development Pasternak, Polish MRC Laboratory of Alan Frederick Walter and Eliza Hall How are Plasmodium falciparum Michał Molecular Biology | Cowman Institute | Parkville, proteins directed to the parasite Cambridge, Australia translocon to reach the host cell? United Kingdom Wrobel, Polish International Institute David C. Cambridge Institute for Autophagy regulators acting via Annexin Lidia of Molecular and Cell Rubinsztein Medical Research (CIMR) | A2 Biology | Cambridge, Warsaw, Poland United Kingdom Guerreiro, Portuguese University of Geneva, Jop Kind Utrecht University, Regulatory dynamics at the Nanog Isabel Switzerland Netherlands locus throughout preimplantation development Monteiro, Portuguese Massachusetts Institute Nuno Sousa Universidade do Minho | STRESSed BRAIN – functional impact of Patricia of Technology (MIT) | Braga, Spain chronic stress exposure on corticostriatal Cambridge (MA), neurons United States Pemovska, Slovene University of Helsinki, Giulio CeMM | Vienna, Austria The triangle connecting nutrient Tea Finland Superti-Furga transport, metabolism and drug sensitivity in blood cancers Boada Romero, Spanish Universidad de Douglas R. Green St. Jude Children's Description and regulation of LAP- Emilio Salamanca, Spain Research Hospital | specific mechanisms Memphis, United States

EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships 33 EMBO Long-Term Fellowships awarded in 2016 | EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project Fernández-Agüera Spanish Universidad | Sevilla, Nika Danial Dana-Farber Cancer Metabolic control of neural excitability: Rodríguez, Spain Institute | Boston, A role for BAD Maria Del Carmen United States Garcia Bermudez, Spanish Centre for Molecular Kivanç Birsoy Rockefeller University | The role of aspartate metabolism in Javier Biology 'Severo Ochoa' | New York, United States cancer cell proliferation Madrid, Spain Garcia Osorio, Spanish University of Oviedo, Fernando Children's Hospital Mechanistic insights into hematopoietic Fernando Spain Camargo Boston | stem cell aging by using a new Boston, United States clonal tracking system and senolytic approaches Gonzalez Grandio, Spanish Centro Nacional de Peter Quail University of California | Dissecting the multiple layers of post- Eduardo Biotecnología (CNB) | Berkeley, United States occupancy modulation of PIF activity Madrid, Spain Iturbide, Spanish Hospital del Mar Medical Maria-Elena Helmholtz Zentrum | Dynamics of chromatin states in Ane Research Institute (IMIM) | Torres-Padilla München, Germany a cellular model for totipotency to Barcelona, Spain pluripotency transition Jimenez Guardeño, Spanish Centro Nacional de Michael H. Malim King's College | London, Identification of host factors involved in Jose Manuel Biotecnología (CNB) | United Kingdom the IFN-induced block to HIV-1 infection Madrid, Spain Martín, Spanish Centre for Research in Paula Duque Instituto Gulbenkian de Role of alternative splicing in cell Guiomar Agricultural Genomics Ciência | Oeiras, Portugal expansion and plant growth (CRAG) | Cerdanyola del Vallès, Spain Montesinos López, Spanish University of Valencia, Eva Benkova Institute of Science and Molecular mechanism of auxin-driven Juan Carlos Spain Technology Austria (IST) | formative divisions delineating lateral Klosterneuburg, Austria root organogenesis in plants Oller-Salvia, Spanish IRBB – Institut de Recerca Jason W. Chin MRC Laboratory of Genetic encoding of phosphothreonine Benjamí Biomedica | Barcelona, Molecular Biology | and its non-hydrolysable and Spain Cambridge, United photocaged derivatives Kingdom Oriola, Spanish Universitat de Barcelona | Jan Brugues MPI für molekulare Active forces shaping the metaphase David Barcelona, Spain Zellbiologie und Genetik | spindle Dresden, Germany Ponce-Salvatierra, Spanish MPI für biophysikalische Marco Marcia EMBL | Grenoble, France Structural and functional studies of viral Almudena Chemie | Göttingen, and host non-coding RNAs involved in Germany HIV infection Povedano Selfa, Spanish Centro Nacional Shahin Rafii Weill Cornell Medical The role of telomerase-mediated Juan Manuel de Investigaciones College | New York, United angiocrine factors during metastasis Oncológicas (CNIO) | States Madrid, Spain

34 EMBO Long-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships awarded in 2016 | EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project Torreno-Pina, Spanish ICFO – The Institute Facundo Batista Ragon Institute of MGH | Identifying and characterizing potential Juan Andres of Photonic Sciences | MIT and Harvard, B cell germline precursors of broadly Castelldefels, Spain United States neutralizing HIV-1 antibodies in HIV-1 vaccinated or HIV-1 freshly infected patients Vento-Tormo, Spanish Universitat de Barcelona | Sarah A. European Bioinformatics Delineating immune cells at the Roser Barcelona, Spain Teichmann Institute | Hinxton | maternal-fetal interface in human early Cambridge, pregnancy one cell at a time United Kingdom Guettou, Swedish Karolinska Institutet | Roland Beckmann Ludwig-Maximilians- Cryo-EM analysis of the yeast Fatma Stockholm, Sweden Universität | München, heptameric post-translational translocon Germany in the membrane environment Malmgren Hill, Swedish University | Gothenburg, David C. Cambridge Institute for Identifying modulators of Beclin 1 Sandra Sweden Rubinsztein Medical Research (CIMR) | regulated autophagy using a CRISPR/ Cambridge, Cas9 system United Kingdom Westman, Swedish Lund University, Sweden Sergio Grinstein Hospital for Sick Children | The role of danger signals in priming the Johannes Toronto, Canada phagocytic response in innate immunity Moor, Swiss Swiss Federal Institute of Shalev Itzkovitz Weizmann Institute of The mammalian apicome – asymmetric Andreas Technology | Lausanne, Science | Rehovot, Israel RNA localization in epithelial tissues Switzerland Pala, Swiss Swiss Federal Institute of Garrett Stanley Georgia Institute of Integration of tactile information across Aurelie Technology | Lausanne, Technology | Atlanta, brain hemispheres Switzerland United States Reinhard, Swiss Universität | Tübingen, Karl Farrow VIB – Flanders Institute Dissecting the neural circuits linking the Katja Germany for Biotechnology | Gent, retina and visually guided behavior Belgium Zimmermann, Swiss ETH Zurich, Switzerland Andrew Goodman Yale University School of Modulation of drug metabolism by Michael Medicine | New Haven, interpersonal microbiome variation United States Oburoglu, Turkish Institut de Génétique Niels-Bjarne Lund University, Sweden Elucidating the metabolic pathways Leal Moléculaire (IGMM) | Woods controlling hematopoietic stem cell Montpellier, France emergence

EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships 35 EMBO Long-Term Fellowships awarded in 2016 | Non-EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project De Silva, American Columbia University | Nicolas Manel Institut Curie | Paris, In vivo functions of nuclear envelope Nilushi New York, United States France rupture and antiviral specialization in dendritic cells DuBuc, American University of Florida | St Uri Frank National University of The molecular basis of sexual Timothy Augustine, United States Ireland | Galway, Ireland development in a cnidarian Gilbert, American University of British Laurent Excoffier University of Bern, Genetic impact of species range Kimberly Columbia | Vancouver, Switzerland expansions and range shifts Canada Hanley, American New York University, Theofanis University of Zurich, The interactions of Cajal-Retzius cells Olivia United States Karayannis Switzerland and GABAergic interneurons in regulating cortical circuit formation Kraushar, American Rutgers University | Christian Spahn Charité - Structural diversity of the ribosome Matthew Piscataway, United States Universitätsmedizin | as a molecular signature of brain Berlin, Germany development analyzed at near-atomic resolution McClure, American Duke University | Durham, John F.X. Diffley Francis Crick Institute | The role of DDK and S-CDK in DNA Allison United States London, United Kingdom replicative helicase activation and origin firing timing Sen, American Rockefeller University | Alexander van Hubrecht Institute | Quantifying symmetric and asymmetric Maya New York, United States Oudenaarden Utrecht, Netherlands divisions in vivo using single-cell sequencing Sorum, American Semmelweis University | Eiríkur University of Iceland | The role of the TRPM1 channel in Ben Budapest, Hungary Steingrímsson Reykjavík, Iceland pigmentation and melanoma Parra, Argentinean University of Buenos Aires, Johannes Soeding MPI für biophysikalische UniDom, Universal database of protein Rodrigo Gonzalo Argentina Chemie | Göttingen, domains Germany Berry, Australian John Innes Centre | Lucas Pelkmans University of Zurich, Mechanisms of transcriptome regulation Scott Norwich, United Kingdom Switzerland by cell volume and surface area Peres, Brazilian University of Sao Paulo, Fiona Powrie University of Oxford, Modulation of regulatory T cells Raphael Brazil United Kingdom responses by microbiota in rheumatoid arthritis Ard, Canadian Wellcome Trust Centre | Sebastian University of Copenhagen, Elucidating the magnitude and Ryan Edinburgh, Marquardt Denmark mechanism of gene regulation through United Kingdom the act of long non-coding transcription in higher organisms Farrow, Canadian University of Calgary, Sarah E. O'Connor John Innes Centre | New frontiers in biohalogenation: from Scott Canada Norwich, United Kingdom discovery to utility of elusive plant chlorinases Gunawan, Canadian University of Toronto, Didier Stainier Max-Planck-Institut Elucidating cellular and molecular Felix Canada für Herz- und mechanisms underlying heart valve Lungenforschung | Bad morphogenesis in live zebrafish embryos Nauheim, Germany

36 EMBO Long-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships awarded in 2016 | Non-EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project Lopez, Canadian McGill University | Alon Chen Max Planck Institute of Comprehensive study of noncoding RNAs Juan Pablo Montreal, Canada Psychiatry | München, in major depression and antidepressant Germany treatment: mechanisms of action Neufeldt, Canadian University of Alberta | Ralf Universität | Heidelberg, Understanding the mechanisms involved Christopher Edmonton, Canada Bartenschlager Germany in the biogenesis of Dengue virus replication complexes Wulff, Canadian University of Oxford, Werner MPI für Biophysik | High resolution structural study of the Bonnie United Kingdom Kühlbrandt Frankfurt, Germany mitochondrial F1Fo-ATP synthase from Polytomella sp. by single particle electron cryomicroscopy Ba, Chinese Radboud University | Nick Franks Imperial College | London, Capturing the neuronal ensembles Wei Nijmegen, Netherlands United Kingdom underlying sleep and sedation Cheng, Chinese National Institute of Melina Schuh MPI für biophysikalische A high resolution 4D atlas of mammalian Shiya Biological Sciences (NIBS) | Chemie | Göttingen, oocyte meiosis Beijing, China Germany Guo, Chinese Jiao Tong University | Matthias MRC Clinical Sciences The dynamics of gene expression and Ya Shanghai, China Merkenschlager Centre | London, 3D chromatin folding in a mammalian United Kingdom developmental system: the role of CTCF and cohesin Li, Chinese Beijing Genomics Institute Nicholas Francis Crick Institute | Joint evolutionary and functional Cai (BGI) | Shenzhen, China Luscombe London, United Kingdom genomic analysis of human transcription start sites in recent history Li, Chinese Chinese Academy of Detlef Weigel MPI für Mechanistic basis of plant autoimmunity Lei Sciences | Beijing, China Entwicklungsbiologie | Tübingen, Germany Tang, Chinese Tsinghua University | Jason W. Chin MRC Laboratory of Photocontrol of protein phosphorylation Shan Beijing, China Molecular Biology | in mammalian cells via genetic encoding Cambridge, of photocaged phosphoserine United Kingdom Revelo Nuncira, Colombian Universität | Göttingen, Geert van den Radboud University | Polarized cytokine release at the Natalia Hasel Germany Bogaart Nijmegen, Netherlands dendritic cell immune synapse Petridou, Cypriot University of Cyprus | Carl-Philipp Institute of Science and The generation and function of Nicoletta Nicosia, Cyprus Heisenberg Technology Austria (IST) | anisotropic tissue tension in zebrafish Klosterneuburg, Austria epiboly Anandapadamanaban, Indian Linköping University, Roger Williams MRC Laboratory of Structural mechanisms underpinning the Madhanagopal Sweden Molecular Biology | negative regulation of mTORC1 Cambridge, United Kingdom Dugar, Indian University | Würzburg, Leendert Hamoen University of Amsterdam, RNA localization in bacteria Gaurav Germany Netherlands

EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships 37 EMBO Long-Term Fellowships awarded in 2016 | Non-EMBC Member States’ nationals Name Nationality Home laboratory Group leader Host laboratory Project Priya, Indian The University of Didier Stainier Max-Planck-Institut Delineating the cytomechanics of cardiac Rashmi Queensland | Brisbane, für Herz- und trabeculation Australia Lungenforschung | Bad Nauheim, Germany Shetty, Indian Indian Institute of Michael N. Hall Biozentrum | University of Exploring novel factors involved in Sunil Science | Basel, Switzerland translation regulation during mTOR Bangalore, India signaling in Hepatocellular Carcinoma Kato, Japanese Kyoto University, Japan Dolf Weijers Wageningen University, Dissecting the complete auxin response Hirotaka Netherlands network in an early-diverging land plant Nagasaka, Japanese The Cancer Institute of Jan-Michael IMP | Vienna, Austria Elucidation of cohesin-mediated spatial Kota JFCR | Tokyo, Japan Peters organization of chromatin structure Abbas, Lebanese Instituto de Biología Jiri Friml Institute of Science and Identification of new regulators on PIN- Mohamad Molecular y Celular de Technology Austria (IST) | FORMED3 polarity Plantas | Valencia, Spain Klosterneuburg, Austria Chew, Malaysian University of Sydney, William Schafer MRC Laboratory of Mechanisms of neuromodulation- Yee Lian Australia Molecular Biology | dependent survival behaviours in Cambridge, Caenorhabditis elegans United Kingdom De Niz, Mexican University of Bern, Matthias Marti , Visualizing malaria transmission stage Mariana Switzerland United Kingdom dynamics: mechanisms mediating Plasmodium gametocyte host-pathogen interactions in the skin Dorobantu, Romanian Utrecht University, Raphael Gaudin Institut de Recherche sur Dynamics of virus-receptor interactions Cristina Netherlands les Maladies Virales et revealed by live single particle and single Hépatiques | Strasbourg, molecule microscopy France Dodonova, Russian EMBL | Heidelberg, Patrick Cramer MPI für biophysikalische Structural plasticity in nucleosomal Svetlana Germany Chemie | Göttingen, arrangements Germany Sarkisyan, Russian Russian Academy of Fyodor Centro de Regulación Experimental exploration of global Karen Sciences | Moscow, Kondrashov Genómica (CRG) | fitness landscape of a protein family Russian Federation Barcelona, Spain Lin, Singaporean Cornell University | Ithaca, Ramanujan S. MRC Laboratory of The mechanisms and substrates of Zhewang United States Hegde Molecular Biology | Ribosome-Associated Quality Control Cambridge, United Kingdom Ku, Taiwanese Heinrich Heine University | Assaf Vardi Weizmann Institute of Coccolithophore-associated microbiome: Chuan Düsseldorf, Germany Science | Rehovot, Israel dynamics and interactions Rodriguez Solovey, Ukrainian Instituto de Biología Jiri Friml Institute of Science and Cell surface receptor complexes for auxin Lesia Natacha Molecular y Celular de Technology Austria (IST) | signaling in plants Plantas | Valencia, Spain Klosterneuburg, Austria

38 EMBO Long-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships 39 EMBO Long-Term Fellowships 2016: Geographical distribution

Applications

Destination Nationality Austrian Belgian Croatian Czech Danish Estonian Finnish French German Greek Hungarian Icelandic Indian (A) Irish Israeli Italian Lithuanian Luxembourgian Maltese Dutch Norwegian Polish Portuguese Singaporean (A) Slovak Slovenian Spanish Swedish Swiss Turkish British Eastern Europe USA/Canada Others Total Austria 2 1 4 3 3 2 2 1 2 2 2 3 2 7 36 Belgium 4 7 1 2 4 1 3 3 1 1 1 2 2 8 40 Croatia 0 Czech Republic 1 1 2 2 6 Denmark 1 1 3 5 1 2 5 1 3 2 2 1 3 2 4 8 44 Estonia 0 Finland 1 1 3 1 2 1 1 10 France 3 2 11 5 2 21 3 11 3 3 3 12 1 3 3 3 9 30 128 Germany 1 2 1 1 1 13 8 4 25 2 19 3 3 3 1 13 2 1 1 5 3 23 24 159 Greece 1 2 1 1 5 Hungary 1 1 2 Iceland 1 1 India (A) 3 3 Ireland 1 2 2 2 1 2 2 1 13 Israel 1 3 3 2 9 1 3 3 1 2 2 30 Italy 3 3 6 14 1 1 1 1 5 35 Lithuania 0 Luxembourg 0 Malta 0 Netherlands 1 5 5 1 9 1 1 2 2 3 8 1 1 3 4 7 54 Norway 1 1 1 1 4 Poland 1 1 2 Portugal 1 1 3 1 1 7 8 1 23 Singapore (A) 2 2 1 2 1 1 9 Slovak Republic 1 1 Slovenia 0 Spain 1 1 1 5 3 2 8 1 4 1 1 1 2 1 5 5 2 11 55 Sweden 1 1 1 3 5 9 2 10 1 2 6 2 2 1 9 1 4 2 4 13 79 Switzerland 1 1 11 19 3 1 15 1 14 1 4 1 6 2 2 3 1 2 2 8 14 112 Turkey 0 UK 2 5 2 1 1 1 20 24 5 3 31 2 7 15 7 4 8 2 30 4 1 6 6 17 50 254 EMBL 1 1 2 1 1 1 2 1 1 3 14 Eastern Europe 1 1 USA/Canada 5 12 3 2 2 3 72 46 5 6 8 4 67 27 23 2 9 14 61 12 6 6 13 1 1 1 411 Others 1 1 1 10 1 1 2 1 4 1 2 4 1 30 Total 13 26 8 12 5 2 13 176 147 29 17 0 170 11 84 117 2 1 1 58 2 35 54 3 3 4 172 21 14 17 40 36 80 188 1561

40 EMBO Long-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships 2016: Geographical distribution

Awards

Destination Nationality Austrian Belgian Croatian Czech Danish Estonian Finnish French German Greek Hungarian Icelandic Indian (A) Irish Israeli Italian Lithuanian Luxembourgian Maltese Dutch Norwegian Polish Portuguese Singaporean (A) Slovak Slovenian Spanish Swedish Swiss Turkish British Eastern Europe USA/ Canada Others Total Austria 1 1 1 1 1 2 2 9 Belgium 1 1 Croatia 0 Czech Republic 0 Denmark 2 1 2 1 1 7 Estonia 0 Finland 0 France 1 1 1 1 4 Germany 2 1 1 3 1 2 1 2 1 5 3 22 Greece 0 Hungary 0 Iceland 1 1 India (A) 0 Ireland 1 1 2 Israel 1 1 1 3 Italy 1 1 1 3 Lithuania 0 Luxembourg 0 Malta 0 Netherlands 1 3 1 1 1 2 9 Norway 0 Poland 0 Portugal 1 1 2 Singapore (A) 0 Slovak Republic 0 Slovenia 0 Spain 1 1 1 1 4 Sweden 1 1 1 1 4 Switzerland 3 8 1 1 2 3 1 2 1 22 Turkey 0 UK 2 2 2 1 1 3 1 1 1 1 3 1 1 2 7 29 EMBL 1 1 2 Eastern Europe 0 USA/Canada 1 2 1 2 6 5 1 9 3 3 7 1 2 2 45 Others 1 1 Total 2 4 2 1 0 0 2 16 24 1 0 0 4 2 13 14 0 0 0 11 0 4 2 1 0 1 15 3 4 1 8 5 14 16 170

EMBO facts & figures 2016 | www.embo.org EMBO Long-Term Fellowships 41 EMBO Advanced Fellowships ➔➔

EMBO Advanced Fellowships, launched in 2014, offer an additional two years of funding for EMBO Long-Term Fellows who demonstrate exceptional progress during their postdoctoral work. The fellowship allows the awardees to complete their postdoctoral research in the host laboratory and to establish their own line of research.

EMBO Advanced Fellowships awarded in 2016 Name Nationality Host laboratory Group leader Project Gomez, American Biozentrum | University of Basel, Peter Scheiffele Functional mapping of a synaptic adhesive code in Andrea Switzerland neurons Eskandarian, French Swiss Federal Institute of Technology | John McKinney Revealing mycobacterial surface physiology using dual Haig Alexander Lausanne, Switzerland atomic force and optical microscopy Rousseau, French MRC Laboratory of Molecular Biology | Anne Bertolotti Characterization of the stress-mediated Adrien Cambridge, United Kingdom assembly pathway Petzold, German Friedrich Miescher Institute | Basel, Nicolas Thomä Understanding the rules of clinically effective targeted Georg Switzerland protein degradation induced by immune modulatory drugs Alfieri, Italian MRC Laboratory of Molecular Biology | David Barford Molecular function of macromolecular assemblies Claudio Cambridge, United Kingdom involved in mitotic progression and maintenance of transcriptional states through mitosis

42 EMBO Advanced Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships ➔➔ EMBO Short-Term Fellowships: Statistics Applications and awards 1977 – 2016 Applications and awards 2000 – 2016 Year Applications Awards Success rate % Country from* Applications % of total Awards % of total Success rate % 2016** 618 350 57 Austria 84 1 44 1 52 2015** 401 (557) 194 (288) 48 (52) Belgium 117 2 80 2 68 2014 548 284 52 Croatia 57 1 28 1 49 2013 560 280 50 Czech Republic 113 2 69 2 61 2012 585 312 53 Denmark 37 1 22 1 59 2011 506 281 55 Estonia 12 <1 8 <1 67 2010 421 219 52 Finland 51 1 27 1 53 2009 495 255 52 France 322 5 205 5 64 2008 395 213 54 Germany 451 6 276 7 61 2007 409 211 52 Greece 209 3 118 3 56 2006 393 194 49 Hungary 151 2 88 2 58 2005 383 201 52 Iceland 16 <1 11 <1 69 2004 301 167 55 Ireland 75 1 45 1 60 2003 289 138 48 Israel 211 3 143 4 68 2002 252 170 67 Italy 1006 14 534 14 53 2001 233 124 53 Luxembourg 2 <1 2 <1 100 2000 274 176 64 Netherlands 195 3 121 3 62 1999 230 138 60 Norway 18 0 9 <1 50 1998 279 143 51 Poland 265 4 140 4 53 1997 339 188 55 Portugal 192 3 107 3 56 1996 316 180 57 Slovak Republic 27 <1 16 <1 59 1995 325 187 57 Slovenia 66 1 36 1 55 1994 369 203 55 Spain 1284 18 678 18 53 1993 376 209 55 Sweden 57 1 38 1 67 1992 351 213 61 Switzerland 73 1 48 1 66 1991 344 194 56 Turkey 147 2 56 1 38 1990 346 211 61 United Kingdom 235 3 148 4 63 1989 331 199 60 Eastern Europe 403 6 182 5 45 1988 351 211 60 Others 1187 17 490 13 41 1987 301 212 70 Total 7063 99 3769 99 53 1986 309 215 70 1985 304 221 73 * “Country from” refers to nationality 1984 320 226 71 1983 335 223 67 ** For reasons of consistency and future compatibility, the annual reporting interval had to be 1982 321 213 66 changed in 2016. The 2016 figures shown include all applications that were decided upon in the 1981 339 235 69 2016 calendar year, including 156 applications that were already reported for 2015. The numbers in brackets are those originally shown in the 2015 EMBO facts & figures brochure, which were 1980 357 242 68 based on the previous reporting interval. 1979 344 243 71 1978 349 244 70 1977 294 213 72

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 43 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Kouidmi, Algerian Université | Montreal, Athanasios Typas EMBL | Heidelberg, High-throughput bacterial genetics to Imene Canada Germany study the biology of the Gram-negative bacterial envelope with an optimized phenotypic assay Drapek, American Duke University | Durham, Niko Geldner University | Lausanne, Defining a minimal gene network to root Colleen United States Switzerland endodermis differentiation Haldipur, American University of Washington | Paula Alexandre University College London, Human-specific cerebellar developmental Parthiv Seattle, United States United Kingdom strategies inform mechanisms of cerebellar evolution and disease pathogenesis Markolovic, American University of Oxford, Joris Messens Vreje Universiteit Brussels, Expanding the known chemistry of Suzana United Kingdom Belgium 2-oxoglutarate-dependent oxygenases: investigation of a potential methionine oxidase Moreno-Roman, American Stanford University, Irina Kolotueva University | Lausanne, Correlative microscopy investigation of Paola United States Switzerland a cell differentiation checkpoint in the Drosophila adult midgut Ruggiero, American University | Syracuse, Roberto Dovesi Università | Torino, Italy Understanding biological vibrational Michael United States relaxation dynamics through the calculation of anharmonicity effects Shea, American Trinity College | Dublin, Amitabha Indian Institute of The impact of mechanical stimuli on BMP Claire Ireland Bandyopadhyay Technology | Kanpur, India and Wnt signalling in the developing joint Steinbrenner, American University of California | Cyril Zipfel The Sainsbury Laboratory | Identification of a legume-specific receptor Adam Berkeley, United States Norwich, United Kingdom for the herbivore-derived peptide elicitor inceptin Stewart, American University | Copenhagen, Konrad Harvard Medical School | Defining the role of replication in somatic Kathleen Denmark Hochedlinger Boston, United States cell reprogramming Acland Strack, Argentinean National University of Ana-Maria Institut Curie | Paris, Role of Leukocyte Specific Protein 1 (LSP1) Rachel Paola Córdoba | Córdoba, Spain Lennon-Dumenil France in the cytoskeleton dynamics of dendritic cells, effects on their migration and adaptive immune response induction Alonso, Argentinean University of Buenos Aires, Anders Swedish University of Dynamic of tyrosine phosphorylation Carlos Agustín Argentina Johannisson Agricultural Sciences | in bicarbonate and cAMP-induced Uppsala, Sweden capacitation Bueno, Argentinean University of Buenos Aires, Tim Sparwasser Medizinische Hochschule | Epigenetic modulation of dendritic cells Carlos Argentina Hannover, Germany during murine cytomegalovirus infection D'Ambrosio, Argentinean Universidad Nacional | Mats Andersson University of Gothenburg | Unraveling the role of Phosphatidylinositol- Juan Martín Mar del Plata, Argentina Göteborg, Sweden phosholipase C 2 (AtPLC2) in defense against non-adapted and adapted in Arabidopsis thaliana Denita Juarez, Argentinean Fundacion Instituto Andrea Bassi Politecnico di Milano | Imaging Ca+2 and Reactive Oxygen Species Silvina Paola Leloir | Milano, Italy (ROS) dynamics in single plants cells using Buenos Aires, Argentina biosensors coupled to Selective Plane Illumination Microscopy (SPIM)

44 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Emiliani, Argentinean Universidad Nacional | Manuel Centre for Research in The role of isoprenoids in the protection Julia Rosario, Argentina Rodriguez- Agricultural Genomics | against UV-B radiation Concepción Barcelona, Spain Giovannoni, Argentinean University of Buenos Aires, Peter Hemmerich Leibniz-Institut fuer Exploring the intrinsic antiviral role of PML Federico Argentina Altersforschung | Jena, against dengue virus Germany Hoijman, Argentinean Universitat Pompeu Fabra | Jon Clarke King's College | London, Geometry of epithelial cavities: making Esteban Barcelona, Spain United Kingdom lumen initiation foci by optogenetics Marchetti, Argentinean Universidad Nacional | Takenaka Mizuki Universität | Ulm, Mitochondrial pentatricopeptide repeats Fernanda Mar del Plata, Argentina Germany (PPR)-containing proteins are essential to sustain embryo development in Arabidopsis thaliana Mayta, Argentinean Instituto de Biología Mohammad-Reza Leibniz-Institut für Evaluating tobacco plants with delayed leaf Martín Molecular y Celular de Hajirezaei Pflanzengenetik und senescence Rosario | IBR, Argentina Kulturpflanzenforschung (IPK) | Gatersleben, Germany Mecchia, Argentinean University of Buenos Aires, Ueli Grossniklaus University of Zurich, Importance of RALF peptides during pollen Martin Argentina Switzerland tube growth in Arabidopsis thaliana Metz, Argentinean Universidad Nacional | Enrique Miguel University | Neuchâtel, Influence of climate on microbial Sebastián Darío San Martín, Argentina Lara Pandis Switzerland eukaryotic diversity as determined by environmental high throughput sequencing Mlewski, Argentinean National University of Emmanuelle Université Diderot (Paris Microbe-mineral interactions and Estela Córdoba | Córdoba, Spain Gérard 7) | Paris, France carbonate precipitation in extreme environments: implications for CO2 storage in carbonates Najle, Argentinean Universitat Pompeu Fabra | Linas Mazutis Vilnius University, On the origin of cell differentiation at the Sebastian Barcelona, Spain Lithuania onset of animals Paparini, Argentinean University of Buenos Aires, John D. Aplin University of Manchester, Effect of VIP on vascular transformation Daniel Esteban Argentina United Kingdom through the modulation of macrophage- trophoblast interactions at early pregnancy Quarracino, Argentinean University of Buenos Aires, José Rodríguez Achucarro Basque Center Characterization of human astrocytic Cecilia Argentina for Neuroscience | alterations: from animal models to patients Zamudio, Spain Roselli, Argentinean National University of Philippe Benaroch Institut Curie | Paris, TLR3 ligand poly A:U based cancer Emiliano Córdoba | Córdoba, Spain France immunotherapy and its effect on the tumor-infiltrating myeloid compartment Scuffi, Argentinean Universidad Nacional | Markus Universität Bonn, Unveiling the role of ROS in H2S-induced Denise Mar del Plata, Argentina Schwarzländer Germany stomatal closure in Arabidopsis thaliana

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 45 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Zárate, Argentinean University of Buenos Aires, Tinna V. Stevnsner Aarhus University, Role of long-term ovarian hormone Sandra Argentina Denmark deprivation and early hormone replacement treatments on base excision repair mechanisms in synaptic and non- synaptic mitochondria from the cortex and hippocampus Nersisyan, Armenian National Academy of Karl Lenhard Leibniz-Institut fuer Telomere shortening induced alteration Lilit Sciences of Armenia | Rudolph Altersforschung | Jena, in the epigenome and transcriptome as a Yerevan, Armenia Germany cause of stem cell and organismal aging Balez, Australian University | Wollongong, Ron M.a. Heeren University | Maastricht, Identifying alterations to the lipid Rachelle Australia Netherlands composition of individual neurite membranes during Alzheimer's disease using human induced pluripotent stem cell models Bargehr, Austrian University of Cambridge | Charles E. Murry University of Washington | Human stem cell derived epicardium in Johannes Cambridge, Seattle, United States myocardial graft development United Kingdom El-Heliebi, Austrian Medical University | Graz, Mats Nilsson Stockholm University, In situ detection of prostate specific Amin Austria Sweden transcripts in prostate cancer by padlock probe technology Heffeter, Austrian Medical University of Gergely Szakacs Research Centre for Collateral sensitivity of multidrug-resistant Petra Vienna, Austria Natural Sciences | cancer cells towards KP772 in vivo Budapest, Hungary Hoernes, Austrian Medical University | Simpson Joseph University of California | Post-transcriptional nucleotide Thomas Innsbruck, Austria San Diego, United States modifications and their impact on protein synthesis Shashkova, Belarusian University | Gothenburg, Mark C. Leake University | York, Observing protein–protein interactions at Sviatlana Sweden United Kingdom single-molecule level in living cells Cox, Belgian Katholieke Universiteit | Cynthia King's College | London, Pituitary deficiency and regeneration: in Benoit Leuven, Belgium Andoniadou United Kingdom search of underlying mechanisms and therapeutic targets with a focus on Wnt/ Lgr5 Cerqueira, Brazilian Ben-Gurion University of Luca Scorrano Università di Padova, Italy In vivo and in vitro role of the neuronal Fernanda the Negev | Beer-Sheva, deubiquitinase UCH-L1 on mitochondria- Israel endoplasmatic reticulum tethering and mitophagy Broad, British Queen Mary | University Taher Karolinska Institutet | An investigation of age-related changes John of London, Darreh-Shori Stockholm, Sweden of expression and function of choline United Kingdom acetlytransferase in the human colon Chalkley, British University of Bristol, Oliver Purcell Massachusetts Institute of Developing predictive methods for Oliver United Kingdom Technology, United States designing minimal/reduced genomes

46 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Davies, British Institute for Medical Georg Borner MPI für Biochemie | Proteomic investigations of adaptor protein Alexandra Research (CIMR) | Martinsried, Germany complex 4 (AP-4) function in human cells Cambridge, United Kingdom Dorling, British University of Oxford, Sergio Filipe Instituto de Tecnologia Hiding behind the wall: exploring PGN Jack United Kingdom Química e Biólogia | recycling in a Gram positive bacterium Oeiras, Portugal and its potential role in host-microbe interaction Lewis, British University of Cambridge | Eric C. Lai Memorial Sloan-Kettering The evolution of endogenous small- Samuel Cambridge, Cancer Center | New York, interfering RNA mechanisms in arthropods United Kingdom United States Lopez-Moya, British University of Alicante | Nicholas J. Talbot University of Exeter, Determining the role of oxidative stress Federico Alicante, Spain United Kingdom and plasma membrane homeostasis in the response of Magnaporthe oryzae and Pochonia chlamydosporia to chitosan Villar Lozano, British Cancer Research UK David Gaynor Kalahari Research Centre | Comparative genomics of mole-rat Diego Cambridge Institute | Kuruman, South Africa enhancer activity: unearthing gene- Cambridge, regulation adaptations to a subterranean United Kingdom environment Wheatley, British University of Oxford, Scott Fraser University of Southern In vivo imaging of key lateral plate Lucy United Kingdom California (USC) | Los mesoderm populations Angeles, United States Zhao, British MRC Laboratory of Hang Lu Georgia Institute of Imaging neuromodulation in C. elegans Buyun Molecular Biology | Technology | Atlanta, Cambridge, United States United Kingdom Hsieh, Canadian University of Edinburgh, Timothy Osborne Sanford-Burnham Macrophage-hepatocyte crosstalk Wei Yuan United Kingdom Medical Research through 25-hydroxylase generation of Institute | La Jolla, 25-hydroxycholesterol in the liver United States Sanders, Canadian University of British Jan Korbel EMBL | Heidelberg, Characterizing structural variants using Ashley Columbia | Vancouver, Germany integrative sequencing technologies to Canada explore normal variation in the human genome Carreras Sureda, Chilean Universidad de Chile | Geert Bultynck Katholieke Universiteit | A novel physiological role of the ER stress Amado Santiago de Chile, Chile Leuven, Belgium sensor IRE1 in fine-tunning mitochondrial function Wang, Chinese University | Copenhagen, Michele Parrinello ETH Zurich, Switzerland Exploring the coupling of ligand binding Yong Denmark and protein dynamics using metadynamics Ye, Chinese Stockholm University, Ralf Bernd Universität | Halle- Solution structure of AtcoreTatA and its Weihua Sweden Klösgen Wittenberg, Germany interaction with lipids: the role of TatA in the twin-arginine transport pathway across the thylakoid membrane

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 47 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Zhang, Chinese Institut Pasteur | Paris, Danielle Malo McGill University | Characterization of the host immune Jing France Montreal, Canada response to Salmonella typhimurium infection in highly susceptible mice Muñoz Lasso, Colombian Centro de Investigacion Mark Pook Brunel University | Study of dynamics of axonal growth of Diana Carolina Principe Felipe (CIPF) | London, United Kingdom sensory neurons from YG8sR mouse model Valencia, Spain for Friedreich's ataxia Dumic-Cule, Croatian University | Zagreb, Serena Zacchigna ICGEB | Trieste, Italy Role of BMP1-3 antibody in preventing Ivo Croatia fibrosis after acute myocardial infarction Miljuš, Croatian Paul Scherrer Institut | Michel Bouvier Université | Montreal, Ligand-induced signalling of human Tamara Villigen, Switzerland Canada cannabinoid CB2 receptor Musa, Croatian Mediterranean Institute Ira Milosevic European Neuroscience Mitochondria-peroxisome interaction and Marina for Life Sciences | Split, Institute | Göttingen, its role in aging Croatia Germany Montalvo Bereau, Cuban Center of Molecular George Coukos University | Lausanne, Deciphering the impact of interleukin-2 Galia Magela Immunology | Havana, Switzerland and rationally designed variants on tumor Cuba vasculature endothelial cells Morales Tarré, Cuban Center of Molecular Alan J. Dickson University of Manchester, Application of 'omics in the metabolic study Orlando Immunology | Havana, United Kingdom of high cell density continuous cell cultures Cuba of recombinant NS0 myeloma cell lines Yabor Cabrera, Cuban Universidad | Ciego de Oscar Vicente Universidad Politecnica | Selection and characterization of bean Lourdes Avila, Cuba Valencia, Spain cultivars resistant to drought and/or salinity Gahura, Czech Biology Centre | Ceske John E. Walker MRC Mitochondrial Structure of F1-ATPase from Trypanosoma Ondrej Budejovice, Biology Unit | Cambridge, brucei Czech Republic United Kingdom Janečková, Czech Institute of Animal Abigail Tucker King's College | London, Impact of matrix metalloproteinases on Eva Physiology and Genetics | United Kingdom tooth development Brno, Czech Republic Polidarova, Czech Academy of Sciences Michael H. MRC Laboratory of Internal topology of the SCN network and Lenka of the Czech Republic | Hastings Molecular Biology | its connectivity with extra-SCN regions Prague, Czech Republic Cambridge, United Kingdom Zálešák, Czech IMBA | Vienna, Austria Antoine Loquet Université de Bordeaux | Signal transduction in Type 3 Secretion Jan Bordeaux, France Systems Groenberg, Danish University | Copenhagen, Jose M. Arguello Polytechnic Institute | Deciphering copper and interaction Christina Denmark Worcester, United States complexes of copper-transporting P-type ATPases O'Sullivan, Danish Aarhus University, Michael Dickinson California Institute of The neuromuscular basis of multifunctional Angela Denmark Technology | Pasadena, motor control during courtship song and United States flight in Drosophila Aleyd, Dutch VU University | Attila Mocsai Semmelweis University | The role of auto-antibodies and Fc Esil Amsterdam, Netherlands Budapest, Hungary receptors in rheumatoid arthritis

48 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Hoffmann, Dutch University | Maastricht, Dennis Burton The Scripps Research Isolation of human autoantibodies against Carolin Netherlands Institute | La Jolla, ion channels and associated proteins United States Jongsma, Dutch Sanquin Research | J Huppa Medical University of Characterize the lacto-glycosphingolipid Marlieke Amsterdam, Netherlands Vienna, Austria influence on MHC class I cell surface organization Smit, Dutch Wageningen University, Siobhan Brady University of California | Identification of potential regulators of Margo Netherlands Davis, United States vascular identity using yeast one hybrid Verbon, Dutch Utrecht University, Louisa Liberman Duke University | Durham, Deciphering the genetic signalling Eline Netherlands United States pathways within the Arabidopsis thaliana root in response to the beneficial microbe Pseudomonas simiae Willemsen, Dutch Instituto de Biología Mark Zwart Wageningen University, Predicting the stability of gene insertions in Anouk Molecular y Celular de Netherlands a plant RNA virus Plantas | Valencia, Spain Yam, Dutch University | Amsterdam, Sarah Spencer RMIT University | Role of the metabolic hormone ghrelin Kit-Yi Yam Netherlands Melbourne, Australia in the early-life stress induced cognitive impairments Gadalla, Egyptian Freie Universität | Berlin, Gisou van der Swiss Federal Institute Identification of DHHC proteins catalysing Mohamed Rasheed Germany Goot of Technology | Lausanne, acylation of HA, a modification essential for Switzerland Influenza virus replication Saar, Estonian University of Cambridge, David Weitz Harvard University | Screening phototrophic organisms for their Kadi-Liis United Kingdom Cambridge, United States exoelectrogenic ability for improving the performance of biological solar cells Saare, Estonian University | Tartu, Estonia Judith Zaugg EMBL | Heidelberg, Age-related epigenetic changes in the Mario Germany monocyte cell population with implications in both innate and adaptive immune system Abreha, Ethiopian Swedish University of Renier A. L. Van University of Oxford, Leaf apoplast proteome profiling of field Kibrom Berhe Agricultural Sciences (SLU) | Der Hoorn United Kingdom grown Solanum species using Activity Alnarp, Sweden Based Protein Profiling (ABPP) Dela Cruz, Filipino University of Santo Irina Druzhinina Vienna University of Molecular phylogeny and in situ DNA Thomas Edison Tomas | Technology | Vienna, barcoding of marine Trichoderma Manila, Philippines Austria associated with the macroalgae Laurentia intermedia (Rhodophyta) and Sargassum piluliferum (Phaeophyta) collected in the Philippines Paavola, Finnish Minerva Foundation Abriel Hugues University | Bern, TRPM4 in cardiac electrophysiology Jere Institute for Medical Switzerland Research | Helsinki, Finland

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 49 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Tarkkonen, Finnish University | Turku, Finland Andre Van Wijnen University of LSD1 target genes and mechanism of Kati Massachusetts | action during osteoblast differentiation Worcester, United States Bailleul, French Institut de Biologie Assaf Vardi Weizmann Institute of Dinoflagellates inhibit diatom Benjamin Physico-Chimique | Paris, Science | Rehovot, Israel photosynthesis France Boulain, French Institut National de la Sam Mugford John Innes Centre | Functional analyses of Myzus persicae Hélène Recherche Agronomique Norwich, United Kingdom salivary genes that are orthologous to the (INRA) | Paris, France key salivary genes of Acyrthosiphon pisum Ferreras, French Newcastle University, Marion University | Bergen, Exploring cell surface glycosaminoglycans Laura United Kingdom Kusche-Gullberg Norway role in transplantation: heparan sulfate 3-O sulfation in renal epithelial cells Fidelin, French Institut du Cerveau et de David McLean Northwestern University | Connectivity mapping of GABAergic spinal Kevin la Moelle épinière (ICM) | Evanston, United States sensory neurons: identification of the Paris, France source of modulation of V2a interneurons, implication for the control of locomotor activity Gouguet, French University of Bordeaux | Sophien Kamoun The Sainsbury Laboratory | Understanding the role of the plasma Paul Bordeaux, France Norwich, United Kingdom membrane raft protein REMORIN in Phythothora infestans disease Gouy De Bellocq, French Institute of Vertebrate Mark Blaxter University of Edinburgh, Population genomics of pinworm parasites Joelle Biology | Brno, United Kingdom in the European house mouse hybrid zone Czech Republic Le Guennec, French French Institute of Health Lucía Katholieke Universiteit | In vitro and cellular analysis of a novel Kilan and Medical Research Chávez-Gutiérrez Leuven, Belgium Alzheimer's disease-related Presenilin-1 (INSERM) | Paris, France partial deletion identified by exome sequencing Louveaux, French École Normale Supérieure | Dolf Weijers Wageningen University, Cell division plane orientation: trade-off Marion Lyon, France Netherlands between two polarizing cues, auxin and mechanical stress Pigeault, French Institut de recherche Pedro Vale University of Edinburgh, The impact of microbiota on Romain pour le développement | United Kingdom transgenerational immune priming in Montpellier, France Drosophila Poirier, French Institut Pasteur | Paris, Benjamin Mount Sinai School of Interplay between the recombination Enzo France TenOever Medicine | New York, of RNA viruses and the activation of United States mammalian innate immunity Rey, French Institute of Experimental Ute Roessner University of Melbourne, Interaction between a host plant genome Elodie Botany | Olomouc, Australia and introgressed chromatin Czech Republic Brungs, German Institute of Aerospace Alamelu Texas Southern University | Impact of AHCC as a nutritional Sonja Medicine | Köln, Germany Sundaresan Houston, United States supplement to obviate immune suppression in (simulated) microgravity

50 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Diepold, German University of Oxford, Matthias Christen ETH Zurich, Switzerland Coordinating Virulence and Cell Cycle: Andreas United Kingdom Integration of the Type III Secretion System within the c-di-GMP regulation system Gebhardt, German Institut Curie | Paris, Isaac Bianco University College London, Neural substrates of binocular vision in the Christoph France United Kingdom zebrafish Gebhart, German University Hospital | Jena, Brian Harvey Royal College of Surgeons E2 KCNQ: beta-catenin in colorectal cancer Veronika Germany in Ireland | Dublin, Ireland Hartmann, German University | Innsbruck, Nektarios National and Kapodistrian Abiotic stress induced metabolomic Anja Austria Aligiannis University | Athens, changes in extremophiles and the Greece discovery of novel molecules with skin protecting activities Helm, German Universität | Göttingen, Bo Huang University of California The dynamic nanoscale organization of Martin Germany San Francisco, core postynaptic proteins United States Herrmann, German Johannes-Gutenberg- Victoria M. University School of Immunomodulatory effects of dimethyl Ann-Kathrin Universität | Mainz, Bolotina Medicine | Boston, fumarate are caused by oxidation of the Germany United States intracellular calcium pump SERCA Imkeller, German Deutsches William Schief The Scripps Research Computer-aided characterization Katharina Krebsforschungszentrum Institute | La Jolla, of antibody binding to Plasmodium (DKFZ) | Heidelberg, United States falciparum circumsporozoite protein Germany Kristen, German Centre for Molecular Paul Saftig Universität | Kiel, Role of LAMP2 in the Alzheimer´s disease- Henrike Biology 'Severo Ochoa' | Germany like neurodegeneration events induced by Madrid, Spain HSV-1 Miesen, German Radboud University | María Carla Saleh Institut Pasteur | Paris, Investigating endogenous piRNA Pascal Nijmegen, Netherlands France biogenesis in adult Aedes mosquitoes Rosendahl, German Universität | Regensburg, Bärbel Rohrer Medical University Investigations into the pathomechanisms Sibylle Germany of South Carolina | of age-related macular degeneration Charleston, United States (AMD): the role of complement in AMD Schiebel, German Philipps-Universität Andrea Cavalli Italian Institute of How ligands actually enter and leave Johannes Marburg, Germany Technology | Genova, Italy binding pockets of proteins Taudt, German University | Groningen, Gavin Kelsey Babraham Institute | Combinatorial chromatin and DNA Aaron Netherlands Cambridge, methylation mapping in early embryo United Kingdom single cells Thangaratnarajah, German Wellcome Trust / Cancer Alexey Amunts Science for Life Laboratory | Molecular mechanism of regulation and Chancievan Research UK Gurdon Solna, Sweden transport of mitochondrial aspartate/ Institute | Cambridge, glutamate carriers by cryo-electron United Kingdom microscopy Wallaschek, German University | Würzburg, Claire University of , EBV-associated gastric carcinoma Nina Germany Shannon-Lowe United Kingdom (EBVaGC): establishment of a novel EBV infection model using 3D human gastric organoids

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 51 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Wallroth, German Leibniz-Institut Lois Weisman University of Michigan | Phosphatidylinositol 3,4-bisphosphate Alexander für Molekulare Ann Arbor, United States in endolysosomal membrane traffic and Pharmakologie (FMP) | nutrient signalling Berlin, Germany Weinert, German Institut D'Investigacions Oxana Eschenko MPI für Biologische Brain-state dependent sensory gating: a Julia Franziska Biomèdiques August Kybernetik | Tübingen, role of noradrenergic modulation Pi i Sunyer (IDIBAPS) | Germany Barcelona, Spain Wiegard, German Heinrich Heine University | Kazuki Terauchi Ritsumeikan University | Towards understanding more complex Anika Düsseldorf, Germany Kusatsu, Japan cyanobacterial circadian clocks – biochemical characterization of a non- standard KaiC protein Zäncker, German GEOMAR | Kiel, Germany Michael Cunliffe Marine Biological Analysis of the marine microbial Birthe Association of the UK | community at the air-sea interface in the Plymouth, Peruvian upwelling regime United Kingdom Arbi, Greek University | Patras, Greece Monica Instituto Gulbenkian de The role of Geminin superfamily members Marina Bettencourt-Dias Ciência | Oeiras, Portugal in centriole biogenesis Chanoumidou, Greek IMBB – FORTH | Heraklion, Henrik Ahlenius Lund University, Sweden GRG5: A novel player in neural commitment Konstantina Greece and generation of induced neuronal cells? Drimyli, Greek Biomedical Sciences Gregg Roman University | Houston, Differential response of a single receptor to Efstathia Research Center United States odorant isotopes 'Alexander Fleming' | Athens, Greece Pavloudi, Greek Hellenic Centre for Marine Michael W. Universität | Bremen, Concurrent activity of sulfate reducing Christina Research | Crete, Greece Friedrich Germany and denitrifying bacteria in the Namibian oxygen minimum zone identified by RNA stable isotope probing Vasilakaki, Greek National and Kapodistrian Klaus Liedl University | Innsbruck, Mapping the catalytic center of Sofia University | Athens, Austria based on their substrate specificity Greece Belic, Hungarian Medical University | Graz, Nitzan Rosenfeld Cancer Research UK Early detection of relapse in patients with Jelena Austria Cambridge Institute | prostate cancer treated with curative Cambridge, radical prostatectomy United Kingdom Borbély, Hungarian Karolinska Institutet | Giuseppe Testa European Institute of Transcriptomic profiling of stem cell Gábor Stockholm, Sweden Oncology (IEO) | Milano, differentiation after endocrine disruptive Italy chemical exposure Bugris, Hungarian Biological Research Claes Von Lund University, Sweden Where are the protons? Studying the Valéria Centre | Szeged, Hungary Wachenfeldt structure of Triose Phosphate Isomerase by neutron crystallography Cseh, Hungarian University | Pécs, Hungary Luca Scorrano Università di Padova, Italy The role of PARP inhibition on Anna Mária mitochondrial dynamics

52 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Mártonfalvi, Hungarian Semmelweis University | Julio Fernandez Columbia University | Folding transitions in native titin molecules Zsolt Budapest, Hungary New York, United States studied at physiological forces Papdi, Hungarian Royal Holloway University Rossana Universitat Autònoma de Entrainment of the Arabidopsis circadian Csaba of London | Egham, Henriques Barcelona | Cerdanyola, clock by nutrient availability through United Kingdom Spain Retinoblastoma related1-mediated histone modifications Sebestyén, Hungarian Eötvös Loánd University | Luis Rivas Centro de Investigaciones Investigation of the anti-Leishmania Mónika Budapest, Hungary Biológicas (CIB/CSIC) | effect and mechanism of action of MTX- Madrid, Spain bioconjugates in vitro Szántai, Hungarian University | Szeged, Rosalinda University | Chieti, Italy Investigation of cardiocytoprotection Ágnes Hungary Madonna of cardiac stem cell-derived cardiac myocytes in vitro, in simulated ischemia/ reoxygenation test system Appadurai, Indian Manonmaniam Dr.joachim Wink Helmholtz-Zentrum für Polyphasic taxonomy identification of Muthamil Iniyan Sundaranar University | Infektionsforschung | novel actinomycete and genome mining of Tirunelveli, India Braunschweig, Germany its biosynthetic pathways Azhikkattuparambil Indian University of Bordeaux | Fritjof Helmchen University of Zurich, Defects in the structural-functional Bhaskaran, Bordeaux, France Switzerland connectivity of S1 to M1 and S2 underlie Arjun object localization/texture discrimination deficits in the Fmr1-/y mouse model of intellectual disability disorder and autism Basu, Indian The Interuniversity Martha Gledhill GEOMAR | Kiel, Germany Dust and mineral iron utilization by Subhajit Institute for Marine natural colonies of the cyanobacteria Sciences | Eilat, Israel Trichodesmium spp. and their associated bacteria Chatterjee, Indian Banaras Hindu University | Alberto Marina Instituto de Biomedicina Crystallographic studies of All2110, Antra Varanasi, India de Valencia (IBV) | Alr0765 and All3014 hypothetical proteins Valencia, Spain from Anabaena PCC 7120 with potency in multiple stress tolerance Ganesan, Indian Konkuk University | Seoul, Alan Dobson University College | Cork, Functional metagenomic approaches to Sathiyanarayanan Republic of Korea Ireland discover polyhydroxyalkanoates from the marine sponge microbiome Ghosh, Indian University of Kalyani | Francois Chevalier Commissariat à l'énergie Role of PARP-1 in DNA repair and Utpal Nadia, India atomique et aux énergies in 3-D chondrosarcoma cells irradiated alternatives | Caen, France with carbon ion beam Jamsheer K., Indian National Institute of Plant Lyubov Ryabova Université | Strasbourg, Examining the role of target of Rapamycin Muhammed Genome Research | New France signalling pathway in plant adaptation to Delhi, India variable light conditions and light stress Joseph, Indian M S Swaminathan Luigi Lucini Università Cattolica del An integrative analysis of genomics, Jenifer Research Foundation | Sacro Cuore | Piacenza, proteomics and metabolomics provides Chennai, India Italy new insights into response mechanism to salt stress in Halophytes

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 53 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Joshi, Indian Bhabha Atomic Research Victor de Lorenzo Instituto Investigaciones Is the bacterial cytoplasm a one-pot Hiren Centre | Kalpakkam, India Biomédicas (CSIC) | reactor? Exploring metabolic channelling Madrid, Spain in Pseudomonas putida Joshi, Indian University of Pune | Pune, Wilfried Schwab Technische Universität | Structural and molecular Rakesh India München, Germany characterization of Vitis vinifera terpene glycosyltransferases (VvdGTs) Kumar Ballamoole, Indian Nitte University | Raz Zarivach Ben-Gurion University of Elucidating the crystal structure of Krishna Mangalore, India the Negev | Beer-Sheva, important protein components of Vibrio Israel parahaemolyticus of type III secretion system More, Indian International Centre for Jyoti Choudhary Sanger Institute | Quantitative proteomic and Kunal | Cambridge, phosphoproteomic analysis of merozoite New Dehli, India United Kingdom stage of human malaria parasite Plasmodium falciparum Nandkishore, Indian National Centre for Michael Schubert Observatoire Conservation of mechanisms patterning Nitya Biological Sciences | Océanologique | mesoderm along the anterior-posterior Bangalore, India Villefranche-sur-mer, axis and evolutionary origin of mesodermal France compartments Natarajan, Indian Centro de Regulación Alexander Stein MPI für biophysikalische In vitro analysis of the Asi mediated ERAD Nivedita Genómica (CRG) | Chemie | Göttingen, Barcelona, Spain Germany Padhi, Indian North Orissa University | Antonio Evidente Università 'Federico II' | Isolation and chemical characterization Srichandan Baripada, India Napoli, Italy of secondary metabolites associated with some endolichenic fungi Rai, Indian University of Helsinki, Susanne Neugart Leibniz-Institut Metabolite accumulation in plants in Neha Finland für Gemüse- und response to solar and simulated UV Zierpflanzenbau | radiation and their interaction with Großbeeren, Germany drought stress Rathore, Indian Science for Life Laboratory | Michal Minczuk MRC Mitochondrial Identification of a new ribosome biogenesis Sorbhi Solna, Sweden Biology Unit | Cambridge, factor in human mitochondria United Kingdom Samal, Indian University | Maastricht, Alfonso Martinez University of Cambridge | Controlling primitive streak and Pinak Netherlands Arias Cambridge, gastrulation-like events in embryoid bodies United Kingdom using 3D microfluidic systems Singh, Indian Northumbria University | Alessio Lodola Università degli Studi di Histone lysine demethylases: insight in to Warispreet Newcastle upon Tyne, Parma, Italy conformational dynamics and free energy United Kingdom of binding from molecular modelling simulations Thorat, Indian Savitribai Phule Pune Hans-Joachim Freie Universität | Berlin, Investigating the neuronal basis Leena University | Pune, India Pflüger Germany of desiccation stress tolerance in Drosophila with reference to the functional significance of biogenic amine neurotransmitters

54 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Verma, Indian Central University of Catherine Curie Unité de Biochimie et Molecular characterization of mineral Shailender Kumar Himachal Pradesh | Physiologie Moléculaire distribution in high grain Fe and Zn wheat- Kangra, India des Plantes (BPMP) | Aegilops derivatives Montpellier, France Walke, Indian Agharkar Research Peter Faller Université | Strasbourg, Modified peptides as chelating agents Gulshan Institute | Pune, India France against Amyloid peptide-Cu complex and associated toxicity in Alzheimer's disease Ramayanti, Indonesian Cancer Center | Anders Ståhlberg University | Gothenburg, Ultrasensitive multiplexed DNA/miRNA Octavia Amsterdam, Netherlands Sweden digital PCR by DNA barcoding for non- invasive disease monitoring and early detection of relapse in blood specimens from patients with nasopharyngeal carcinoma Mosaffa, Iranian Universitat Politecnica Yanlan Mao University College London, Numerical simulation of wound healing Payman de Catalunya | Barcelona, United Kingdom Spain Belton, Irish University College | Enrique Flores Instituto de Bioquímica Using a triparental mating system to Samuel Dublin, Ireland Vegetal y Fotosíntesis deliver gene-replacement constructs to the (IBVF) | Sevilla, Spain cyanobacterium Nostoc punctiforme for the generation of knockout Bourke, Irish Wageningen University, Christine Hackett The James Hutton Double reduction and its implications for Peter Netherlands Institute | Invergowrie, QTL mapping in polyploid species United Kingdom Duncan, Irish Trinity College | Dublin, Nicola Partridge New York University, Analysis of the expression, distribution and Henry (hal) Ireland United States role of selected class II histone deacetylases in mineralising dental pulp tissue Kearney, Irish Royal College of Surgeons Jonathan Garlick Tufts University | Boston, Fabrication of tissue engineering Cathal in Ireland | Dublin, Ireland United States scaffolds for diabetic wound healing using extracellular matrix from induced pluripotent stem cell-derived fibroblasts Lyons, Irish Aarhus University, Arne Möller MPI für Biophysik | Structural characterisation of yeast Joseph Denmark Frankfurt, Germany P4-type ATPase using cryo-electron microscopy Maher, Irish University of Oxford, Ewa Rajpert-De University | Copenhagen, Identifying clones of mutant Geoffrey United Kingdom Meyts Denmark spermatogonia in human testes Mullins, Irish King's College | London, Naomi Wray The University of Integration of 'omics' datasets to Niamh United Kingdom Queensland | Brisbane, understand the biology of major depressive Australia disorder Afanzar, Israeli Weizmann Institute of Richard Berry University of Oxford, Study of single CheY molecules with Oshri Science | Rehovot, Israel United Kingdom respect to binding of the flagellar motor and acetylation

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 55 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Avitan Hersh, Israeli Technion | Haifa, Israel Ze'Ev Ronai Sanford-Burnham The role of RNF4, a SUMO-targeted- Emily Medical Research ubiquitin-ligase, in melanoma Institute | La Jolla, development and resistance to United States Ben Or-Frank, Israeli Ben-Gurion University of Gerhard Holzapfel Technical University | Graz, Image-based analysis of soft collagenous Mor the Negev | Beer-Sheva, Austria tissues Israel Beryozkin-Munitz, Israeli The Hebrew University | Uwe Wolfrum Johannes-Gutenberg- Development of new avenues of treatments Avigail Jerusalem, Israel Universität | Mainz, for retinal degenerations Germany Britstein, Israeli University of Haifa | Haifa, Ana Riesgo Natural History Museum | Molecular mechanisms of host-microbe Maya Israel London, United Kingdom interaction in marine sponges Burgsdorf, Israeli University of Haifa | Haifa, Kim M. Handley University of Auckland, From free living existance to intracellular Ilia Israel New Zealand symbiosis: genomic features of the facultative symbiont Candidatus Synechococcus feldmannii David, Israeli Tel Aviv University, Israel Reuven Agami Netherlands Cancer Profiling of active enhancers bound by Ahuvit Institute | Amsterdam, RPE-specific-TFs: focusing on the roles of Netherlands the Ldb/Lhx2 complex in transcription regulation at the RPE Even, Israeli Tel Aviv University, Israel Laurent Nguyen University | Liège, Belgium The Elongator complex is recruited to Aviel neuronal vesicles where it controls retrograde transport via acetylation of motor proteins Mayseless, Israeli Weizmann Institute of Andre Fiala Universität | Göttingen, Interneuronal communication during Oded Science | Rehovot, Israel Germany developmental neuronal remodeling in Drosophila Nagler, Israeli Weizmann Institute of Daniel Peeper Netherlands Cancer Identifying new genetic modifiers in Adi Science | Rehovot, Israel Institute | Amsterdam, response to MEK targeted therapy in NRAS Netherlands mutant melanoma Nisani, Israeli Weizmann Institute of Eckhard Wolf Ludwig-Maximilians- In vivo investigations of the putative tumor Sophia Science | Rehovot, Israel Universität | München, suppressor gene Tshz2 in a knockout Germany mouse model Schleyer, Israeli Weizmann Institute of Joern Piel ETH Zurich, Switzerland Deciphering the metabolic landscape Guy Science | Rehovot, Israel during host-virus interactions of the bloom-forming phytoplankton Emiliania huxleyi Ambrosetti, Italian University | Trieste, Italy Ana Teixeira Karolinska Institutet | Her2 localization, dimerization, shedding Elena Stockholm, Sweden in living cells: a nanotechnology and super- resolution fluorescence approach Bortot, Italian Università degli Studi | David Fushman University of Maryland | Polyubiquitin-chain recognition by Andrea Verona, Italy College Park, nanoparticle receptors United States

56 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Calì, Italian Università di Padova, Italy Pablo Vargas Institut Curie | Paris, Targeting chemokine signalling Bianca France to modulate cancer cells nuclear deformability Callegari, Italian Swiss Federal Institute Davide Mazza Università Vita-Salute San Quantitative FRAP (qFRAP) assessment of Andrea of Technology | Lausanne, Raffaele | Milano, Italy p65-NFkB binding kinetics in living cells Switzerland Cappelletti, Italian Fondazione Edmund Paola Picotti ETH Zurich, Switzerland Large scale mass spectrometry-based Valentina Mach | San Michele analysis of protein structural changes all'Adige, Italy during the unicellular-to-multicellular epigenetic transition in natural yeast Carlon, Italian University of Florence | Garib Murshudov MRC Laboratory of Improving the integration of NMR in Azzurra Sesto Fiorentino, Italy Molecular Biology | macromolecular structure refinement Cambridge, software United Kingdom Carpi, Italian Università | Pisa, Italy Vincenzo Cerullo University of Helsinki, Evaluation of the combination of immune Sara Finland checkpoint inhibitors with oncolytic vaccines in cutaneous melanoma models Carusone, Italian CNR | Napoli, Italy Joel L. Sussman Weizmann Institute of Structure determination of proteins of Teresa Maria Science | Rehovot, Israel biotechnological interest: expression of Sulfolobus acidocaldarius PLL and the human paraoxonase PON2 in E. coli and insect cells Cella Zanacchi, Italian ICFO – The Institute Michael Pusch Advanced Biotechnology Quantitative single molecule localization Francesca of Photonic Sciences | Centre | Genova, Italy studies of CLC-Kb/Barttin chloride channels Castelldefels, Spain Ciregia, Italian Università | Pisa, Italy Arturo Sala Brunel University | Investigating the role of exosomes in MYCN Federica London, United Kingdom tumourigenesis Cordella, Italian Istituto Superiore di Salvatore Valitutti Centre de Looking at a melanoma cell and its Martina Sanita | Roma, Italy Physiopathologie de microenvironment Toulouse-Purpan | Toulouse, France Corso, Italian Free University of Brussels, Alex Costa Università degli Studi | Study of intracellular calcium dynamics Massimiliano Belgium Milano, Italy and stress response mediated by CCX2 and CAX1 genes in Arabidopsis Corvino, Italian Università 'Federico II' | Annalisa Pastore King's College | London, Fragment-based de novo design of a Angela Napoli, Italy United Kingdom cystathionine gamma-lyase selective inhibitor blocking hydrogen sulfide production Cristofani, Italian Università degli Studi | Giampietro University College London, Deficits in axonal retrograde transport in Riccardo Maria Milano, Italy Schiavo United Kingdom motor neuron diseases Cuomo, Italian Stazione Zoologica Anton Veronica Hinman Carnegie Mellon Evolution of a gene regulatory network for Claudia Dohrn | Naples, Italy University (CMU) | gut development Pittsburgh, United States

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 57 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project De Pascalis, Italian Institut Pasteur | Paris, Xavier Trepat Institut de Bioenginyeria Assessing the role of intermediate filaments Chiara France de Catalunya (IBEC) | in collective cell migration through forces Barcelona, Spain Della Torre, Italian Università degli Studi | Nina Henriette Helmholtz Zentrum | HEROIC_AGE: Hepatic Estrogen ReceptOr Sara Milano, Italy Uhlenhaut München, Germany alpha and the Incidence of NAFLD and Cardiovascular diseases in AGEing women Foglietta, Italian Università | Torino, Italy Giulio C. Spagnoli University of Basel, Engineered perfused three dimensional Federica Switzerland models: first steps towards a new tailored pharmacology approach in breast cancer Franchi, Italian Università di Padova, Italy L. Courtney Smith The George Washington Factor H from echinoderms: growing Nicola University | Washington, complexity of the invertebrate innate United States immunity Gastaldello, Italian University | Southampton, Anthony Purcell Monash University | Identifying peptide candidates for a vaccine Annalisa United Kingdom Clayton, Australia against the contagious cancer, devil facial tumour disease Gatta, Italian University College London, Anne-Claude EMBL | Heidelberg, Protein-lipid interactome landscape of Alberto United Kingdom Gavin Germany LAMs Ghini, Italian Università degli Studi | Irit Sagi Weizmann Institute of Integrating 'OMICS': metabolomics & Veronica Firenze, Italy Science | Rehovot, Israel proteomics to study IDB Gravino, Italian Università 'La Sapienza' | Saskia Hogenhout John Innes Centre | Role of plant cell wall and cell wall-derived Matteo Roma, Italy Norwich, United Kingdom oligogalacturonides in defense against aphids Lauria, Italian University | Trento, Italy Guido Sanguinetti University of Edinburgh, RiboWaves: development of a Fabio United Kingdom mathematical model of eukaryotic translation integrating ribosomes and RNA binding proteins occupancies by multi- dimensional profiles Magrì, Italian Università degli Studi | Jeff Abramson University of California | Crystallization of voltage dependent anion Andrea Catania, Italy Los Angeles, United States selective channel isoform 3 (VDAC3) Malinverni, Italian Josep Carreras Leukaemia Amos Tanay Weizmann Institute of Genome-wide analysis of the role of Roberto Foundation | Barcelona, Science | Rehovot, Israel macroH2A histone variants in chromatin Spain architecture and nuclear organization Masgras, Italian Università di Padova, Italy Lu Q. Le University of Texas TRAPping the metabolic adaptations of Ionica Southwestern Medical NF1-associated tumors Center | Dallas, United States Maturo, Italian University | L'Aquila, Italy Rajiv Kumar Deutsches Characterization of TERT in basal Maria Giovanna Krebsforschungszentrum cell carcinoma (DKFZ) | Heidelberg, Germany Melloni, Italian Istituto Italiano di Eleftheria Zeggini Sanger Institute | Next generation association studies in Giorgio Tecnologia (IIT) | Milano, Cambridge, isolated populations Italy United Kingdom

58 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Menga, Italian Universita | Bari, Italy Massimiliano Vesalius Research Center | Unraveling the molecular mechanisms Alessio Mazzone Leuven, Belgium underlying the oncosuppressive role of slc25a26 in Mercatelli, Italian Università degli Studi | Philipp Selenko Leibniz-Institut Atomic-resolution analysis of protein– Eleonora Firenze, Italy für Molekulare protein interactions in live cells Pharmakologie (FMP) | Berlin, Germany Mirabelli, Italian ETH Zurich, Switzerland Janusz Pawliszyn University of Waterloo | Direct SPME-DBDI-MS coupling for rapid, Mario Francesco Waterloo, Canada ultrasensitive and non-chromatographic analysis of drugs and metabolites in human body fluids Monteleone, Italian Università | Torino, Italy Pier Paolo Beth Israel Deaconess STAT3-dependent pluripotency control via Emanuele Pandolfi Medical Center (BIDMC) | stem-cell specific lincRNAs Boston, United States Montemiglio, Italian Università degli Studi di Amedee Des New York University, Cryo-EM structure of the HIPK2- Linda Celeste Roma 'Tor Vergata' | Rome, Georges United States complex, the key to oncosuppression in Italy DNA-damaged cells Ottaviani, Italian Università di Padova, Italy Michael University College London, Protein kinase CK2 phosphorylates Daniele Cheetham United Kingdom the HSJ1 chaperone and modulates its neuroprotective function Passaro, Italian The Francis Crick Institute | David Fooksman Albert Einstein College Intravital observation of the bone marrow Diana London, United Kingdom of Medicine | New York, in long bones United States Pennisi, Italian Università degli Studi Thomas Helleday Science for Life Laboratory | The interplay between the DNA damage Rosa Roma Tre | Roma, Italy Solna, Sweden response and metabolism in cancer cell proliferation Pilotto, Italian Università | Pavia, Italy Daniela Rhodes Nanyang Technological Structural studies of LSD2-NPAC and LSD1- Simona University Singapore, CoREST1 in complex with nucleosome by Singapore CryoEM Pinamonti, Italian International School for Noé Frank Freie Universität | Berlin, RNA base fraying: a molecular dynamics Giovanni Advanced Studies | Trieste, Germany study analyzed with Markov state models Italy Poli, Italian University | Brescia, Italy Jeffrey Esko University of California Hepcidin, iron and heparan sulfates Maura San Diego | La Jolla, United States Rosini, Italian University of Insubria | Dario Neri ETH Zurich, Switzerland A targeted enzymatic therapy based on Elena Varese, Italy oxidative stress: a promising tool for cancer treatment Sagheddu, Italian University of Cagliari | István Katona Institute of Experimental Molecular adaptations in brain reward Claudia Cagliari, Italy Medicine of the system following prenatal cannabinoid Hungarian Academy of exposure Sciences, Hungary

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 59 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Santorelli, Italian Telethon Institute of Ryoichiro Kyoto University, Japan Characterization of a synthetic ultradian Marco Genetics & Medicine Kageyama oscillator in a mammalian cell line (TIGEM) | Pozzuoli, Italy Simonini, Italian John Innes Centre | Darren Hart EMBL | Grenoble, France 3D structure of ETT-IND-auxin complex Sara Norwich, United Kingdom Terreri, Italian CNR | Napoli, Italy Ramiro Garzon Ohio State University | Function of T-UCRs and approaches to Sara Columbus, United States T-UCR-protein interactions Turrà, Italian National University of Robert Arkowitz Université | Nice, France Unravelling the mechanisms of plant David Córdoba | Córdoba, Spain peroxidase-mediated activation of hyphal chemotropism in F. oxysporum Vigevani, Italian Centro de Regulación Jernej Ule University College London, Spliceosome iCLIP applied to samples Luisa Genómica (CRG) | United Kingdom treated with splicing inhibitors Barcelona, Spain Aizawa, Japanese ETH Zurich, Switzerland Mitinori Saitou Kyoto University, Japan Generation of primordial germ cells from Eishi mouse embryonic stem cells in vitro Hikita, Japanese Max-Planck-Institut Michiyuki Kyoto University, Japan Analysis of planar cell polarity in Takao für Herz- und Matsuda endothelial homeostasis Lungenforschung | Bad Nauheim, Germany Yosuke, Japanese University of Helsinki, Ulrike Engel Universität | Heidelberg, Regulation of cell–cell adhesions by I-BAR Senju Finland Germany domain proteins Yubuki, Japanese Charles University in Patrick J. Keeling University of British Unravelling the origin(s) of the euglenid Naoji Prague | Prague, Columbia | Vancouver, plastid through the exploring the genome Czech Republic Canada and transcriptome of a mixotrophic euglenophycean: Rapaza virdis Kazlauskas, Lithuanian Vilnius University, Mart Krupovic Institut Pasteur | Paris, Distribution and diversity of archaeo- Darius Lithuania France eukaryotic DNA replication proteins in bacteria and their mobile genetic elements Randriamanana, Malagasy University of Eastern Nathaniel Street Umeå University, Sweden Metagenomic surveys and functions of Tendry Finland | Joensuu, Finland foliar endophytes in aspen under climate change Camargo Sosa, Mexican University | Bath, Christiane MPI für Characterisation of the role of endothelin Karen United Kingdom Nüsslein-Volhard Entwicklungsbiologie | signalling pathway in the establishment Tübingen, Germany of adult pigment stem cells in zebrafish development Flydal, Norwegian University | Bergen, Juan Hermoso Instituto de Química Structural basis for regulation of Marte Norway Física Rocasolano | phenylalanine hydroxylase activity Madrid, Spain Hussain, Pakistani National Institute for Toby Bruce Rothamsted Research | Identifing aphid (Rhopalosiphum padi and Momina Biotechnology and Harpenden, Schizaphis graminum) resistance traits Genetic Engineering | United Kingdom in a well characterised mutant wheat Fasialabad, Pakistan population

60 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Joudeh, Palestinian Cajal Institute | Madrid, Edward Bayer Weizmann Institute of Incorporation of resurrected glucanases Nadeem Spain Science | Rehovot, Israel into designer cellulosomes to study the evolution of cellulolytic systems Celinska, Polish University of Life Sciences | Jean-Marc Nicaud INRA | Jouy-en-Josas, 'Golden Gate' concept-based tools for Ewelina Poznan, Poland France metabolic engineering of nonconventional yeast species Yarrowia lipolytica Ciechomska, Polish National Institute of Vladimir Benes EMBL | Heidelberg, Global profiling and functional analysis Marzena Geriatrics | Rheumatology Germany of miRNA in monocytes from rheumatoid and Rehabilitation, Poland arthritis and systemic sclerosis patients Czarnecki, Polish University | Warsaw, Didier Mazel Institut Pasteur | Paris, Dissection of the molecular mechanism of Jakub Poland France stable maintenance of two chromosomes in Vibrio cholerae – study of interactions between initiator replication proteins DnaA and RctB Dudka, Polish University of Geneva, Andrew D University of Warwick | What is the role of tension in mitosis in Damian Switzerland McAinsh Coventry, United Kingdom human cells? Focht, Polish Aarhus University, Jonathan Javitch Columbia University | Investigation of the binding site specificity Dorota Denmark New York, United States and functional characterization of bacterial homologue of neurotransmitter: sodium symporters – MhsT Focht, Polish Aarhus University, Matthias Quick Columbia University | Investigation of the binding site specificity Dorota Denmark New York, United States and functional characterization of bacterial homologue of neurotransmitter: sodium symporters – MhsT Heberlein, Polish University of Münster, Florian Hollfelder University of Cambridge, Evolution of substrate specificity in the Magdalena Germany United Kingdom alkaline phosphatase superfamily Kisiel, Polish Medical University | Lucia Sivilotti University College London, Structural determinants and the impact of Magdalena Wroclaw, Poland United Kingdom neurosteroids on preactivation transitions in GABAA receptor Kobierecka, Polish University | Warsaw, Luis Bermudez INRA | Jouy-en-Josas, Characterization of the lactobacillus spp. Patrycja Poland Humarán France temperature-induced promoters and their used to express Campylobacter jejuni genes Modelska, Polish University | Trento, Italy Alexey Amunts Science for Life Laboratory | Structural characterization of the Angelika Solna, Sweden mitoribosome from glioblastoma stem cells bound to a potential anti-glioblastoma compound Nazimek, Polish Jagiellonian University | Francisco Servicio de Immunología | Investigation of exosome-mediated Katarzyna Krakow, Poland Sánchez-Madrid Madrid, Spain interaction of antigen-presenting macrophages with T effector lymphocytes at the immune synapse

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 61 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Orczyk, Polish University of Technology | Gerald Brezesinski Max Planck Institut The influence of steroidal and triterpenoid Marta Warsaw, Poland für Kolloid und saponins on an outer leaflet model of Grenzflächenforschung | human erythrocytes' membrane Potsdam, Germany Perycz, Polish Institute of Jeremy Lynch University of Illinois | DNA methylation and demethylation Malgorzata and Biophysics | PAS, Chicago, United States machinery gene knock out in Nasonia Poland insect model with Cas9 and TALENs gene editing systems Pirzgalska, Polish Instituto Gulbenkian de Christopher Glass University of California The neuro-adipose connection and its Roksana Ciência | Oeiras, Portugal San Diego | La Jolla, immune regulators United States Roszak, Polish University of Cambridge | Siobhan Brady University of California | Gene regulatory networks controlling Pawel Cambridge, Davis, United States phloem development and vascular pattern United Kingdom formation Socha, Polish University of Medical Malte Spielmann Charité – Coding vs. non-coding: deciphering the Magdalena Sciences | Poznan, Poland Universitätsmedizin | underlying causes for the congenital limb Berlin, Germany malformations (CLMs) in a cohort of Polish patients with the use of the whole genome sequencing (WGS) Woźniak, Polish Jagiellonian University | Stephen J. G. Galer Max Planck Institut für Calcium isotope ratio (44/42 Ca) analysis in Barbara Krakow, Poland Chemie | Mainz, Germany the context of reaching the peak bone mass in past populations Ząbczyńska, Polish Jagiellonian University | Maja Pucic Genos | Zagreb, Croatia Glycosylation of serum glycoproteins in Marta Krakow, Poland Bakovic Hashimoto thyroiditis Amorim, Portuguese Instituto de Biologia Noel Miranda University Medical Analysis of mitotic fidelity and João Molecular e Cellular Centre | chromosomal instability in primary (IBMC) | Porto, Portugal Leiden, Netherlands colorectal tumor cells Barbosa, Portuguese Institut D'Investigacions Timothy J. Princeton University, Neural mechanisms underlying working Joao Biomèdiques August Buschman United States memory feature binding Pi i Sunyer (IDIBAPS) | Barcelona, Spain Castanheira Dias, Portuguese Centro Nacional de Felipe Cava Umeå University, Sweden Application of Ultra-Performance Liquid Sónia Marisa Biotecnología (CNB) | Chromatography (UPLC) to unravel Madrid, Spain activity of two Salmonella enterica serovar Typhimurium-specific proteins predicted to contribute to peptidoglycan metabolism inside eukaryotic cells Conniot, Portuguese University | Lisbon, Ronit Tel Aviv University, Israel Study of the in vivo immune therapeutic João Portugal Satchi-Fainaro effect of a nanovaccine candidate on a melanoma cancer model Diaz, Portuguese National University of Imre Berger EMBL | Grenoble, France MultiBac baculovirus insect cell expression Suraya Ireland | Galway, Ireland of four-subunit human DNA polymerase alpha-primase

62 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Estrada, Portuguese Instituto de Tecnologia Cathrin Brisken Swiss Federal Institute Advanced culture systems to study Marta Química e Biólogia | of Technology | Lausanne, hormone-mediated paracrine signalling in Oeiras, Portugal Switzerland mammary gland Fernandes, Portuguese Universidade do Algarve | Richard James Hill University | Portsmouth, Investigate the role of annexin A2 in Lina Faro, Portugal United Kingdom human glioblastoma Miranda-Lourenço, Portuguese Instituto de Medicina Detlev Boison Legacy Research Institute | Regulation of adenosine levels as a new Catarina Molecular | Lisbon, Portland, United States therapeutic strategy for Portugal Moreira Tavares, Portuguese Institut Gustave Roussy | Wolf-Dietrich University of California | Multiprotein integrative model of Eliana Raquel Villejuif, France Heyer Davis, United States homologous recombination Oliveira, Portuguese Instituto de Biologia Mark Buttner John Innes Centre | Role and molecular mechanisms of a novel Rute Molecular e Cellular Norwich, United Kingdom ECF sigma factor: identification of SigG (IBMC) | Porto, Portugal regulon Pereira Pereira, Portuguese University College London, Judith Campisi Buck Institute for Interaction between the immune system Branca Isabel United Kingdom Research on Aging | and senescent cells Novato, United States Vila-Viçosa, Portuguese University | Lisbon, Chris Oostenbrink University of Natural Enhanced sampling techniques to Diogo Portugal Resources & Life Sciences improve constant-pH molecular dynamics (BOKU) | Vienna, Austria simulations of peptides at the water/ membrane interface Chimerel, Romanian University of Cambridge, Sylvie Rabot Institut National de la The role of the bacterial metabolite indole Catalin United Kingdom Recherche Agronomique in the modulation of GLP-1 secretion from (INRA) | Paris, France enteroendocrine cells in vivo Pena, Romanian Institute of Biochemistry | Neil Bulleid University of Glasgow, The role of P5 (PDIA6) in the maturation of Florentina Bucharest, Romania United Kingdom Collagen type IV Alexandrov, Russian Russian Academy of Daniel The Hebrew University | Imaging and genetic analysis of Alexander Sciences | Moscow, Kaganovich Jerusalem, Israel respiration-dependent protein aggregation Russian Federation in response to hyperosmotic shock in yeast Lomakina, Russian Russian Academy of Alexis Gautreau Laboratoire Role of novel Rac effectors in the control of Maria Sciences | Moscow, d'Enzymologie et persistence of cell migration Russian Federation Biochimie Structurales (LEBS) | Gif-sur-Yvette, France Franek, Slovak Institute of Biophysics | Thomas Küntziger University | Oslo, Norway Dynamic analysis of nuclear body Michal Brno, Czech Republic reorganization using BioID Kaiser, Slovak Masaryk University | Brno, Carlos Villaescusa Karolinska Institutet | Study of the mechanism of secretion Karol Czech Republic Stockholm, Sweden and distribution of WNT proteins in the embryonic central nervous system Laláková, Slovak Karolinska Institutet | Pekka Katajisto University of Helsinki, Exploring the role of Jana Stockholm, Sweden Finland inheritance in stemness using human stem-like cells and Snap-tag

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 63 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Porubsky, Slovak European Research Tobias Marschall Max Planck Institute Use of single-cell strand sequencing and David Institute for the Biology for Informatics | long-read technologies to phase diploid of Ageing | Groningen, Saarbruecken, Germany genomes Netherlands Frajman, Slovene University | Innsbruck, Bengt Oxelman University | Gothenburg, Disentangling diversification patterns Bozo Austria Sweden within the Heliosperma pusillum group (Caryophyllaceae) from the southern European mountains using gene capture and next generation sequencing Krajnc, Slovene Josef Stefan Institute | Jacques Prost National University of Active dynamics of tissues: a 3D vertex Matej Ljubljana, Slovenia Singapore, Singapore model for tissue morphogenesis Sobotic, Slovene Josef Stefan Institute | Anna Blom Lund University | Malmö, Involvement of extracellular cathepsins in Barbara Ljubljana, Slovenia Sweden complement regulation in cancer Srpan, Slovene University of Manchester, Björn Önfelt Karolinska Institutet | Microchip-based single-cell imaging of Katja United Kingdom Stockholm, Sweden the dynamics of NK cell interactions with their targets engaging different activating receptors Du Plessis, South African Stellenbosch University | R Wigneshweraraj Imperial College | London, Structure, function and inhibition of RNA Juanelle Cape Town, South Africa United Kingdom polymerase in Mycobacterium tuberculosis Moses, South African University | Cape Town, Laura Batlle Centro de Regulación Identifying the precise molecular Stacey South Africa Morera Genómica (CRG) | pathogenesis underlying the disease Barcelona, Spain phentoype in individuals carrying a in the spliceosomal factor, PRPF8 Aguilera Herce, Spanish Universidad | Sevilla, Adam Schikora Julius Kühn Institut Expression and effects of Salmonella Julia Spain für Epidemiologie und enterica type III secretion system effectors Pathogendiagnostik | in plants Braunschweig, Germany Alvarez Arguedas, Spanish Universidad | Zaragoza, Roland Brosch Institut Pasteur | Paris, Characterization of the PE/PPE proteins in Samuel Spain France the live attenuated M. tuberculosis vaccine MTBVAC Álvarez Teijeiro, Spanish University | Oviedo, Spain Pedro Queen Mary | University Quantitative mass spectrometric analysis Saúl Rodriguez-Cutillas of London, of secretome from head and neck United Kingdom squamous cell carcinomas Arroyo López, Spanish Universidad de Jaén | Jaén, Duncan J. Clarke University of Minnesota | Does MCPH1 modulate G2/M arrest María De La Cabeza Spain Minneapolis, induced by Topoisomerase II inhibition? United States Barrientos Moreno, Spanish Estación Experimental del Miguel Cámara University of Nottingham, Connections between amino acid Laura Maria Zaidín | CSIC, Spain García United Kingdom metabolism, c-di-GMP levels and posttranscriptional regulators of the RsmA/CsrA family in Pseudomonas putida KT2440

64 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Blanca Ramírez, Spanish Instituto de Parasitología Maddy Parsons King's College | London, Alterations in motility as cellular readout Marian y Biomedicina 'López- United Kingdom for pathogenic LRRK2 in Parkinson's Neyra' (IPBLN) | Granada, disease Spain Bosch Fortea, Spanish Centre for Molecular Benoit Ladoux Institut Jacques Monod | Design of a micropattern-based device to Minerva Biology 'Severo Ochoa' | Paris, France study cell mechanics and forces during Madrid, Spain renal tubulogenesis Bullich, Spanish Universitat Autonoma Rachel Giles University Medical Functional study on the tmem104 Gemma de Barcelona | Barcelona, Centre (UMC) | Utrecht, gene and its potential involvement in Spain Netherlands the ethiology of autosomal dominant tubulointerstitial kidney disease Bustamante, Spanish Centre for Research in Kerstin Kaufmann Humboldt-Universitaet zu Genome-wide screening for CUP SHAPED Mariana Agricultural Genomics | Berlin, Germany COTYLEDON1 interacting proteins Barcelona, Spain Cabezudo, Spanish Centre for Molecular Ana Maria Cuervo Albert Einstein College Role of Galphaq-coupled receptors in the Sofía Biology 'Severo Ochoa' | of Medicine | New York, modulation of autophagy Madrid, Spain United States Calvo Sánchez, Spanish Universidad Ramon y Richard Meehan MRC Human Genetics Development of an improved methodology María Inmaculada Cajal | Madrid, Spain Unit | Edinburgh, for the regulated silencing of DNTM1 in United Kingdom multiple cell types that will allow for the design of new experimental approaches to study the roles of this protein in vivo with basic and translational purposes Castro, Spanish Universidad Complutense Shehab Ismail Beatson Institute for Idetification of PRL-1 substrates and Patricia de Madrid (UCM) | Madrid, Cancer Research | interacting proteins in the context of T cell Spain Glasgow, United Kingdom activation Cemeli, Spanish Universitat de Lleida | Lluis Fajas University | Lausanne, Kinome analysis of the membrane- Tania Lleida, Spain Switzerland associated Ccnd1-Cdk4 complex Díaz, Spanish Universidad de Marie-Caroline Le Hôpital Paul Brousse | Transform bone marrow-derived neural David Salamanca, Spain Bousse-Kerdiles Villejuif, France cells for enhancing neuroprotection Espinosa Medina, Spanish Institute of Biology of the Alan Burns University College London, Defining a vagal neural crest dichotomy Isabel ENS | Paris, France United Kingdom during enteric nervous system formation Estarellas, Spanish Universitat de Barcelona | Francesco University College London, Cellular retinol-binding proteins: which Carolina Barcelona, Spain Gervasio United Kingdom are the factors that modulate the distinct affinity for retinol in CRBP-I and CRBP-II isoforms? Fernandez Castillo, Spanish Universitat de Barcelona | Alejandro Radboud University | Combined transcriptomic and GWAS Noelia Barcelona, Spain Arias-Vasquez Nijmegen, Netherlands analysis to identify genes and pathways that contribute to cocaine dependence Fernandez Mateos, Spanish Universidad de Nicola Valeri Institute of Cancer Establishment of GI tumour-derived Javier Salamanca, Spain Research | London, organoids (TDOs) and their use in United Kingdom biomedical research

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 65 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Fernandez, Spanish Universidad Complutense Elena Kozlova Uppsala University, The dorsal root angioarchitecture in Julia de Madrid (UCM) | Madrid, Sweden intact rodents and following injury and Spain regenerative strategies Flores Romero, Spanish University of the Basque Ana Jesus Garcia Universität | Tübingen, The role of mitochondrial lipids as well as Hector Country | Leioa, Spain Saez Germany two poorly understood BCL2-type proteins, BFL1 and BCLB, in the membrane activities of BAX using advanced fluorescence microscopy techniques Fraile Bethencourt, Spanish University | Valladolid, Emanuele Buratti ICGEB | Trieste, Italy Splicing regulation of an atypical GC donor María Eugenia Spain in breast cancer genes Fuster, Spanish University of Cambridge, Alessandra Biffi Dana-Farber Cancer NeuroIMMUNE interactions via WNT3A in Almudena United Kingdom Institute | Boston, the Stroke Brain (IMMUNE_WNT3a) United States Gallardo-Chamizo, Spanish CABIMER | Sevilla, Spain Alfred Vertegaal University Medical Centre | Analysis of SUMOylation during ischemia- Francisco De Asís Leiden, Netherlands like conditions in differentiated neurons Garcia Pardo, Spanish Universitat de Barcelona | Tom L. Blundell University of Cambridge, Structural characterization of the full- Javier Barcelona, Spain United Kingdom length human carboxypeptidase D Garcia-Canadilla, Spanish Universitat Pompeu Anne Bonnin Paul Scherrer Institut | Reconstruction and visualization of X-ray Patricia Fabra | Villigen, Switzerland micro-CT synchrotron based images from Barcelona, Spain cardiac tissue samples García-Negredo, Spanish Universitat de Barcelona | Paola Pedarzani University College London, Deciphering the role of calmodulin and Gloria Barcelona, Spain United Kingdom Homer proteins in the mGlu5 receptor-SK2 ion channel interaction Gibert, Spanish Hospital del Mar Medical Sebastian Leidel MPI für Molekulare A molecular high throughput approach Joan Research Institute (IMIM) | Biomedizin | Münster, to decipher the role of RNA translational Barcelona, Spain Germany control by CPEB1 in pancreatic cancer González Sainz Spanish Centro Nacional Jennifer Nichols University of Cambridge | Phenotyping of Nanog conditional knock De Aja, de Investigaciones Cambridge, out mice: Study of Nanog's role in lineage Julio Cardiovasculares (CNIC) | United Kingdom specification Madrid, Spain Gonzalez Teran, Spanish Centro Nacional Eric Olson University of Texas Role of p38 MAPK pathway in cardiac Barbara de Investigaciones Southwestern Medical regeneration Cardiovasculares (CNIC) | Center | Dallas, Madrid, Spain United States Hernansanz, Spanish Universidad Autonoma | Mike Murphy MRC Mitochondrial Oxidative damage in ischemia-reperfusion Pablo Madrid, Spain Biology Unit | Cambridge, injury, interplay between ions, electrons United Kingdom and oxygen Ibañez Robles, Spanish Universität | Halle- Salomé Prat Centro Nacional de Hormonal crosstalk regulation of PIF4 in Carla Wittenberg, Germany Biotecnología (CNB) | thermomorphogenesis signaling Madrid, Spain Iribar, Spanish BioDonostia Health Shunichi Women's Medical Implication of neural competent cells of Haizea Research Institute | Morikawa Hospital | Tokyo, Japan murine ventral dermis in wound healing San Sebastian, Spain

66 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Lara Astiaso, Spanish Weizmann Institute of Felipe Prósper Center for Applied Medical Patient specific characterization of David Science | Rehovot, Israel Cardoso Research | Pamplona, genomic regulatory elements associated Spain with normal and malignant B development Liceras Boillos, Spanish Universidad (CSIC) | Anne Ridley King's College | London, Study of the role of Sos proteins in cell Mª Pilar Salamanca, Spain United Kingdom migration and adhesion López Arias, Spanish Universidad Autonoma | Oliver Craig University | York, Paleogenomics as a tool to explore the Begoña Madrid, Spain United Kingdom ancient fisheries of the Iberian Peninsula López, Spanish University | Oviedo, Spain Emma Shanks Beatson Institute for Strategic evaluation of synergistic drug Alejandro Cancer Research | candidates coupled to inhibition of mTOR Glasgow, United Kingdom for treatment of oral and sinonasal cancers Madrigal, Spanish CEU Cardenal Herrera Alain Chedotal Institut de la Vision | Paris, Role of RhoE in axon guidance: 3D axonal Pilar University | Valencia, France tracts characterization in RhoE gt/gt mouse Spain Maicas, Spanish Instituto de Biomedicina Maria Luisa IMP | Vienna, Austria Determination of the genome-wide binding Miren de Valencia (IBV) | Cochella profile of transcription factors from a single Valencia, Spain neuron pair in C. elegans Majuelos, Spanish Instituto de Parasitología Rajat Singh Newcastle University, Unraveling the role of PARP in lipophagy in Jara y Biomedicina 'López- United Kingdom glioblastoma multiforme Neyra' (IPBLN) | Granada, Spain Marques-Bueno, Spanish École Normale Supérieure | Jiri Friml Institute of Science and Control of Auxin signaling for endocytosis Maria Del Mar Lyon, France Technology Austria (IST) | regulation by Membrane Associated Kinase Klosterneuburg, Austria Regulator 2 Menéndez-Montes, Spanish Centro Nacional Hesham Sadek University of Texas Characterization of the metabolic Iván de Investigaciones Southwestern Medical signature and regenerative capacity of Cardiovasculares (CNIC) | Center | Dallas, embryonic, neonatal and adult HIF1a Madrid, Spain United States positive cardiomyocytes from a lineage tracing perspective Molinuevo Llaría, Spanish Universidad de Cantabria | James T. Elder University of Michigan | Identifying novel genes controlling Rut Santander, Spain Ann Arbor, United States squamous differentiation Montoliu-Gaya, Spanish Universitat Autonoma Rob Veerhuis VU University | Study of the effects of the scFv-h3D6 Laia de Barcelona | Barcelona, Amsterdam, Netherlands in Abeta aggregation and cellular Spain uptake, alone or in combination with apolipoproteins E and J Nieto Garcia, Spanish Centro Nacional de Jorge Casal Fundacion Instituto Functional analysis of effects of COP1 and Cristina Biotecnología (CNB) | Leloir | phyB on ELF3 and PIF4 protein levels under Madrid, Spain Buenos Aires, Argentina warm temperatures in Arabidopsis Ortega, Spanish Universidad Complutense Silvia Cappello Max Planck Institute of Characterization of the expression and Felipe de Madrid (UCM) | Madrid, Psychiatry | München, function of P2X7 purinergic receptors Spain Germany during the development of the human cortex: a study based on cerebral organoids method

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 67 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Palomo Guerrero, Spanish Universitat Internacional Harald Stenmark The Norwegian Radium Study of Cpt1c regulation of late Marta de Catalunya | Barcelona, Hospital | Oslo, Norway endosomes transport along the axon, in Spain relation to hereditary spastic paraplegia Pedraza Arévalo, Spanish National University of Marika Queen Mary | University Epigenetic and post-transcriptional Sergio Córdoba | Córdoba, Spain Charalambous of London, regulation of sst5 gene expression and its United Kingdom implication in the aberrant expression of alternative spliced isoforms Pérez Hernández, Spanish University | Valencia, Chantal Centre de recherche Extracellular vesicle associated microRNAs Javier Spain Boulanger Cardiovasculaire à l'HEGP | as new mediators in atherosclerosis Paris, France Perez-Rando, Spanish University | Valencia, Anthony Medical Center | Geneva, Fluoxetine-induced structural plasticity in Marta Spain Holtmaat Switzerland the mouse cerebral cortex in vivo Perretta, Spanish Universidad de Daivd Long University College London, Role of Cardiotrophin-1 in the progression Núria Salamanca, Spain United Kingdom of glomerulonephritis Planas Marques, Spanish Ramon Llull University | Wolfgang Parak Philipps-Universität Photoheranostic gold nanoclusters: light- Oriol Barcelona, Spain Marburg, Germany based diagnosis and treatment of cancer using novel metal nanomaterials Prat-Ortega, Spanish Institut D'Investigacions Tobias Donner University | Hamburg, Mechanisms of cortical dynamics during Genis Biomèdiques August Germany perceptual decision making Pi i Sunyer (IDIBAPS) | Barcelona, Spain Ramos Sanchez, Spanish Universidad Politechnica | Philip Wigge University of Cambridge, Deciphering photoperiod-induced Jose Manuel Madrid, Spain United Kingdom amplitude changes in LHY2 Requena Soria, Spanish Centre for Molecular Richard Mann Columbia University | Wing primordium specification in David Biology 'Severo Ochoa' | New York, United States Drosophila Madrid, Spain Rodriguez-Ubreva, Spanish Institut d'Investigacio Gavin Kelsey Babraham Institute | Single-cell genome-wide bisulfite Javier Biomedica de Bellvitage Cambridge, sequencing of B cell subsets of a pair of (IDIBELL) | Barcelona, United Kingdom monozygotic twins discordant for common Spain variable immunodeficiency Roura Frigolé, Spanish Institute for Research in Yitzhak Tor University of California Development of a high-throughput Helena Biomedicine | Barcelona, San Diego | La Jolla, fluorescence-based assay for drug Spain United States discovery Saenz De Juano Spanish Free University of Brussels, Gavin Kelsey Babraham Institute | Effect of in vitro follicle culture and Ribes, Belgium Cambridge, superovulation on mouse oocyte DNA Maria Dels United Kingdom methylation establishment Desemparats Sáenz, Spanish CIBIR – Center for Hilde Nilsen University | Oslo, Norway Does a NABP1-INTS Complex function in Beatriz Biomedical Research of La DNA repair in C. elegans? Rioja | Logrono, Spain Salvador Gallego, Spanish Universität | Tübingen, Gia Voeltz University of Colorado | The role of Bax in regulating mitochondrial Raquel Germany Boulder, United States dynamics at the molecular level

68 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Sánchez Spanish Universidad | Sevilla, Doris Marko University | Vienna, Toxicological properties of novel Barrionuevo, Spain Austria polyphenolic compounds with Leyre pharmacological applications Sánchez-Higueras, Spanish Universidad Pablo de Richard S. Mann Columbia University | Molecular regulation of DNA cis-regulatory Carlos Olavide | Sevilla, Spain New York, United States elements Sanz Sender, Spanish Insituto de Salud Global Rhoel Dinglasan Johns Hopkins University | Function and mechanism of O-fucosylation Silvia de Barcelona | Barcelona, Baltimore, United States of malaria parasite TSR-domain proteins Spain Soriano, Spanish University of Oxford, Philippe Pasero CNRS Institute of Human Mutations in replicative DNA polymerases Ignacio United Kingdom Genetics | Montpellier, associated with cancer predisposition France Tello-Lafoz, Spanish Centro Nacional de Morgan Huse Memorial Sloan-Kettering Role of SNX27 in cytoskeletal and Maria Biotecnología (CNB) | Cancer Center | New York, membrane remodeling during immune Madrid, Spain United States synapse formation Terriente-Felix, Spanish Institute for Research in Sarah Bray University of Cambridge, Characterization of a Drosophila model of Ana Biomedicine | Barcelona, United Kingdom myeloproliferative disorders Spain Tomàs Gamisans, Spanish Universitat de Barcelona | Mhairi Workman Technical University Optimizing 13C-glycerol labelling Màrius Barcelona, Spain of Denmark | Lyngby, experiments for metabolic flux analysis Denmark in Pichia pastoris growing on glycerol as single carbon source Torregrosa-Crespo, Spanish University of Alicante | Lars R. Bakken Norwegian University of Transcriptional and physiological studies of Javier Alicante, Spain Life Sciences (UMB) | Ås, denitrification in Haloferax mediterranei Norway Torres Sanchez, Spanish University of Cadiz | Cadiz, Rita J. Valentino University of Pennsylvania | The effect of Deep Brain Stimulation Sonia Spain Philadelphia, (DBS) on stress-induced changes in United States pontine-cortical network activity. Possible mechanism of action for its antidepressant activity Vidal Gómez, Spanish University | Valencia, Maria Carmen Université | Angers, France Isolation, characterization and use of Xavier Spain Martinez extracellular vesicles in the study of endothelial function Zevallos, Spanish Johannes-Gutenberg- Elena Verdu McMaster University | Microbial modulation of gut dysfunction Victor Universität | Mainz, Hamilton, Canada triggered by amylase trypsin inhibitor (ATIs) Germany in NOD-DQ8 mice Ahmed, Swedish Stockholm University, Inger Greve Alsos University | Tromsø, Past floral diversity and climate change Engy Sweden Norway recorded in sedimentary ancient DNA Meister, Swiss Swiss Federal Institute Adam S. Lauring University of Michigan | Fitness cost of environmental disinfection- Simon of Technology | Lausanne, Ann Arbor, United States resistant enteric virus isolates Switzerland

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 69 EMBO Short-Term Fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Pfammatter, Swiss University Hospital | Tuomas Knowles University of Cambridge | Development of a digital amyloid Manuela Zurich, Switzerland Cambridge, amplification assay for the ultrasensitive United Kingdom detection and quantification of amyloid aggregates Pirondini, Swiss Swiss Federal Institute Stephanie R. Jones Brown University | Exploring corticothalamic correlates of Elvira of Technology | Lausanne, Providence, United States EEG recorded activity in essential tremor Switzerland patients Rufener, Swiss University | Bern, Jia Li Imperial College | London, Host-pathogen interaction between Reto Switzerland United Kingdom Echinococcus multilocularis and host cells: starving a deadly helminth Chen, Taiwanese University of Cologne, Maurijn van der Leiden University, Immune response and the regulation of Yen-Ta Germany Zee Netherlands immune effectors in the embryo of the milkweed bug Oncopeltus fasciatus Lee, Taiwanese Ludwig-Maximilians- Margus Pooga University | Tartu, Estonia Cell entry and intracellular trafficking Dian-Jang Universität | München, of oligoaminoamide-based polycationic Germany siRNA vectors Aktas, Turkish Universitat Rovira i Virgili Aart Van Wageningen University, Development of simple, fast and low Gulsen Betul (URV) | Tarragona, Spain Amerongen Netherlands cost lateral flow assays based on signal amplification mediated by a HRP-DNA binding protein conjugate Özçirak Ergün, Turkish Yildiz Technical University | Daniel Huson Universität | Tübingen, Discovering microbial profile with Şeyma Istanbul, Turkey Germany metagenomics approach in an environmental sample peculiar to Turkey to enhance industrial enzymes Tuzlakoglu Öztürk, Turkish Institute of Technology | Gislene Pereira Universität | Heidelberg, Functional analysis of coiled-coil domain- Merve Gebze, Turkey Germany containing protein 124 (Ccdc124) in centrosome biology and Kurinna, Ukrainian ETH Zurich, Switzerland James Dooley Katholieke Universiteit | Mir-29 regulates cutaneous wound healing Svitlana Leuven, Belgium through keratinocyte migration and differentiation Piven, Ukrainian Institute of Molecular Cecilia Winata International Institute Eluciating the signaling function of Oksana Biology and Genetics | of Molecular and Cell beta-catenin and plakoglobin in heart Kyiv, Ukraine Biology | Warsaw, Poland development using genome-wide ChIP-seq Shkrabak, Ukrainian National Academy of Andrey Université | Strasbourg, Plasma membrane coated fluorescent Oleksandr Sciences of Ukraine | Kyiv, Klymchenko France nanoparticles as the new tool for Ukraine glioblastoma imaging Dangarembizi, Zimbabwean University of the Christoph Justus-Liebig-Universität | The anti-inflammatory effects of Rachael Witwatersrand Medical Rummel Giessen, Germany Perlagonium sidoides extracts on School | Johannesburg, neuroglial cells stimulated with South Africa lipopolysaccharide and Brewer's yeast

70 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org ERS | EMBO joint fellowships awarded in 2016 Name Nationality Home laboratory Group leader Host laboratory Project Dousova, Czech University Hosptial Margarida Amaral University of Lisboa | Assessment of disease liability of CFTR Tereza Motol | Lisboa, Portugal mutations in primary tissues from patients Prague, Czech Republic with cystic fibrosis and response to CFTR modulators Hvass, Danish Aarhus University Delia Goletti IRCCS Lazzaro Spallanzani | Deciphering the CD8+ T-cell response to Andreas Fløe Hospital | Rome, Italy latentphase Mycobacterium Tuberculosis Aarhus, Denmark antigens Derks, Dutch Maastricht University Lynette International Agency for Identification of molecular subgroups Jules Medical Center | Fernandez-Cuesta Research on Cancer | Lyon, of pulmonary large cell neuroendocrine Maastricht, Netherlands France carcinoma (LCNEC) with clinical relevant phenotypes in stage IV disease Biondini, Italian University of Padova | Oliver Eickelberg Ludwig-Maximilians Validation of biomarkers identified from Davide Padova, Italy University and Helmholz experimentally induced pulmonary fibrosis Zentrum | Munich, in patients with idiophatic pulmonary Germany fibrosis

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 71 EMBO Short-Term Fellowships 2016: Geographical distribution

Applications

To From* Austria Belgium Croatia Republic Czech Denmark Estonia Finland France Germany Greece Hungary Iceland India (A) Ireland Israel Italy Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Singapore (A) Republic Slovak Slovenia Spain Sweden Switzerland Turkey UK EMBL Eastern Europe USA/Canada Others Total Austria 1 1 1 1 1 1 3 1 1 11 Belgium 1 1 1 2 1 1 2 4 13 Croatia 1 1 Czech Republic 2 1 1 1 5 Denmark 1 1 2 2 1 1 8 Estonia 1 1 Finland 1 1 1 3 France 1 1 1 1 11 3 1 1 2 4 11 4 3 1 10 55 Germany 1 1 1 2 3 6 5 8 2 4 1 15 1 2 3 1 3 19 78 Greece 1 1 Hungary 1 1 1 1 4 Iceland 0 India (A) 1 1 Ireland 1 1 2 1 5 Israel 1 2 2 1 2 1 1 10 Italy 1 1 1 2 3 1 5 1 1 1 2 1 1 5 26 Lithuania 1 1 Luxembourg 0 Malta 0 Netherlands 2 1 2 1 1 1 2 1 1 10 1 2 3 28 Norway 1 1 1 3 1 1 1 9 Poland 1 1 1 3 Portugal 1 1 1 3 Singapore (A) 1 1 1 3 Slovak Republic 1 1 Slovenia 0 Spain 1 1 1 1 3 1 1 3 1 1 1 1 2 1 18 37 Sweden 2 1 1 1 1 1 1 1 5 1 1 1 5 3 7 32 Switzerland 1 1 2 1 1 3 1 1 5 2 2 5 25 Turkey 1 1 UK 1 2 4 1 5 3 4 2 14 3 2 3 44 3 3 2 3 5 13 117 EMBL 1 1 2 1 2 2 9 Eastern Europe 0 USA/Canada 1 1 6 1 5 13 2 1 1 5 2 12 4 1 3 27 4 1 14 104 Others 1 1 1 3 1 1 1 2 2 1 1 3 1 4 23 Total 9 5 3 11 10 1 6 19 27 13 7 0 35 10 18 62 1 0 1 18 2 16 12 0 1 3 143 8 10 7 42 0 12 17 89 618

* “From” refers to home laboratory (see list on pages 44 – 71)

72 EMBO Short-Term Fellowships EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 2016: Geographical distribution

Awards

To From* Austria Belgium Croatia Republic Czech Denmark Estonia Finland France Germany Greece Hungary Iceland India (A) Ireland Israel Italy Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Singapore (A) Republic Slovak Slovenia Spain Sweden Switzerland Turkey UK EMBL Eastern Europe USA/Canada Others Total Austria 1 1 1 1 1 2 1 8 Belgium 1 1 1 1 1 1 6 Croatia 1 1 Czech Republic 0 Denmark 1 1 1 3 Estonia 1 1 Finland 1 1 2 France 1 5 2 1 1 3 7 2 2 3 27 Germany 1 1 2 1 3 4 4 1 3 10 1 2 2 1 6 42 Greece 1 1 Hungary 1 1 1 3 Iceland 0 India (A) 1 1 Ireland 1 1 2 Israel 1 1 2 1 2 1 8 Italy 1 1 1 2 2 1 2 1 1 1 1 1 15 Lithuania 1 1 Luxembourg 0 Malta 0 Netherlands 1 1 2 1 6 1 12 Norway 1 3 1 1 6 Poland 1 1 Portugal 1 1 2 Singapore (A) 1 1 2 Slovak Republic 0 Slovenia 0 Spain 1 1 1 2 1 1 1 1 1 4 14 Sweden 2 1 1 1 1 3 1 1 2 3 2 18 Switzerland 1 1 1 1 1 3 1 3 1 2 3 18 Turkey 0 UK 1 2 4 5 3 1 2 8 3 1 2 25 3 3 1 2 4 70 EMBL 1 1 1 2 2 7 Eastern Europe 0 USA/Canada 1 1 5 1 4 8 1 1 2 1 9 3 1 3 11 4 11 67 Others 1 2 1 1 1 2 1 3 12 Total 7 3 2 8 7 1 5 15 19 5 5 0 14 5 15 36 1 0 0 12 1 11 9 0 0 2 77 7 10 2 30 0 6 7 28 350

* “From” refers to home laboratory (see list on pages 44 – 71)

EMBO facts & figures 2016 | www.embo.org EMBO Short-Term Fellowships 73 EMBO Young Investigators

www.embo.org/funding-awards/young-investigators [email protected]

Launched in 2000, the programme has supported 389 scientists in 19 EMBC Member States. Gerlind Wallon Researchers from Singapore, Taiwan and India have joined the programme due to cooperation Programme Manager agreements signed in 2011, 2012 and 2016 respectively. The EMBO Young Investigators benefit from training opportunities designed to raise their profile, widen their networks and support their research groups.

EMBO Young Investigators 2016 Name Nationality Institute Research interest Country Igor Adameyko Swedish Center for Brain Research, Medical University of Skeletal development and regeneration AT Vienna Bungo Akiyoshi Japanese University of Oxford Unconventional trypanosome kinetochores UK Stefan Ameres German Institute of Molecular Biotechnology of the Austrian RNA silencing AT Academy of Sciences, Vienna Yosef Buganim Israeli The Hebrew University-Hadassah Medical School, Nuclear reprogramming and embryonic cell fate IL Jerusalem Jeremy Carlton British King's College London Membrane remodeling during mitosis UK Ana Cvejic British University of Cambridge Blood development UK Christophe Dessimoz Swiss University of Lausanne and University College Phylogenetic analysis UK London Ana Jesus Garcia Saez Spanish Interfaculty Institute of Biochemistry, University of Membrane dynamics during cell death DE Tuebingen Jerome Gros French Institut Pasteur Vertebrate limb formation FR Annika Guse German Centre for Organismal Studies, Molecular basis of symbiosis DE Grzegorz Kudla Polish MRC Institute of Genetics & Molecular Medicine, Quantitative RNA biology UK University of Edinburgh Martin Lenz French The French National Center for Scientific Research Cytoskeletal mechanics FR and University of Paris-Sud Michelle Linterman New Babraham Institute, Cambridge The ageing immune system UK Zealander Ana Claudia Marques Portuguese The University of Lausanne Intergenic long noncoding RNAs CH Miratul Muqit British University of Dundee, School of Life Sciences PINK1 kinase signalling UK John O'Neill British MRC Laboratory of Molecular Biologyn Cellular rhythms and metabolic regulation UK Giulia Rancati Italian Agency for Science, Technology and Research, A-STAR Adaptive evolution in eukaryotes SG

74 EMBO Young Investigators EMBO facts & figures 2016 | www.embo.org EMBO Young Investigators 2016 Name Nationality Institute Research interest Country Jan Rehwinkel German Weatherall Institute of Molecular Medicine, Innate immune receptors UK University of Oxford Pere Roca-Cusachs Spanish Institute for Bioengineering of Catalonia and Cellular mechanosensing ES University of Barcelona Suzan Rooijakkers Dutch University Medical Center Utrecht Complement and bacteria NL Carmine Settembre Italian Telethon Institute of Genetics and Medicine, Naples Lysosome-autophagy pathway IT Minhajuddin Indian Institute for Stem Cell Biology and Regenerative Regulation of microtubules IN Sirajuddin Medicine, Bangalore Kikue Austrian Institute of Molecular Biotechnology of the Austrian Oocyte-to-zygote transition AT Tachibana-Konwalski Academy of Sciences, Vienna Igor Ulitsky Israeli Weizmann Institute of Science, Rehovot Long noncoding RNAs IL Claire Wyart American Brain & Spine Institute, Université Pierre et Marie The interface between cerebrospinal fluid and FR Curie, Paris central nervous system

EMBO facts & figures 2016 | www.embo.org EMBO Young Investigators 75 EMBO Young Investigators 2000 – 2016

A Bühler, Marc E Hidalgo, Alicia L Mazzone, Massimiliano Adameyko, Igor Bujnicki, Janusz Einsle, Oliver Hiller, Sebastian Labib, Karim Mehlen, Patrick Adams, Ralf Bumann, Dirk Elena, Santiago Hirst, Judy Lakadamyali, Melike Meier, Pascal Agami, Reuven Elf, Johan Hoffmann, Eva Längst, Gernot Meraldi, Patrick Ahel, Ivan C Etienne-Manneville, Holstege, Frank Lappalainen, Pekka Miguel-Aliaga, Irene Akiyoshi, Bungo Cabernard, Clemens Sandrine Hoogenraad, Casper Lecuit, Thomas Milán, Marco Alimonti, Andrea Carballido-Lopez, Rut Ettema, Thijs Hopfner, Karl-Peter Legube, Gaëlle Milo, Ron Allain, Frédéric Carleton, Alan Eulalio, Ana Hoppe, Thorsten Lehner, Ben Miska, Eric Alon, Uri Carlton, Jeremy Hothorn, Michael Lemaitre, Bruno Mitchell, Kevin Ameres, Stefan Carroll, Jason F Huertas, Pablo Lenz, Martin Mizuno, Naoko Huisken, Jan Møller, Simon Geir Amit, Ido Carter, Andrew Fankhauser, Christian Leulier, François Hummel, Thomas Morillon, Antonin Antonny, Bruno Chaves Simoes De Fernández-Capetillo, Levashina, Elena Arber, Silvia Carvalho, Pedro Nuno Óscar Leys, David Mosialos, George Arkowitz, Robert Casares, Fernando Fernández-Chacón, I Linterman, Michelle Mota, Maria Arribas, Joaquin Cavaillé, Jérôme Rafael Iannacone, Matteo Liu, Hai-Kun Muqit, Miratul Ashe, Hilary Chin, Jason Fischer, André Itzkovitz, Shalev Logan, Malcolm Musacchio, Andrea Asher, Gad Chiti, Fabrizio Friml, Jiří Ivaska, Johanna Logan, Darren Averof, Michalis Choudhary, Chunaram Fuks, François Lohmann, Jan N Azzalin, Claus Maria Christoforidis, Savvas J Lopes, Massimo Nagy, László Clausen, Tim López-Bendito, G Jacobs, Jacqueline Nakamura, Yuki Collinson, Ian Guillermina B Garcia Saez, Ana Jesus Janke, Carsten Navarro, Lionel Conradt, Barbara Lorentzen, Esben Barkai, Naama Garel, Sonia Jansen, Ralf Nehrbass, Ulf Corona, Davide Lovering, Andrew Barr, Francis Garinis, George Jarriault, Sophie Neuhauss, Stephan Cortés Ledesma, Felipe Löwe, Jan Barral, Yves Geldner, Niko Jefferis, Gregory Nichols, Benjamin Cosma, Maria Pia Lüdde, Tom Barre, François-Xavier Gerhardt, Holger Jensen, Torben Heick Nissen, Poul Costanzo, Vincenzo Luke, Brian Basler, Marek Gerlich, Daniel Jensen, Kim Nollen, Ellen Cowling, Victoria Lygerou, Zoi Basto, Renata Gil, Jesús Jessberger, Sebastian Norden, Caren Cramer, Patrick Batista, Facundo Ginhoux, Florent Jinek, Martin Noselli, Stéphane Currie, Peter Baum, Buzz Glotzer, Michael Jouvenet, Nolwenn M Cvejic, Ana Bäurle, Isabel Gönczy, Pierre Jovine, Luca Madan Babu, M. O Behrens, Axel González-Reyes, Mailand, Niels O’Neill, John D Beja, Oded Acaimo K Mäkinen, Taija Odom, Duncan Bellaïche, Yohanns d’Adda di Fagagna, Gotta, Monica Málnási Csizmadia, Kaessmann, Henrik Oldroyd, Giles Ben-Yehuda, Sigal Fabrizio Grill, Stephan András Kaufmann, Kerstin Otzen, Daniel Benton, Richard Daumke, Oliver Gros, Jerome Mansuy, Isabelle Keays, David Owen, David Berezikov, Eugene Davis, Daniel Groth, Anja Manzanares, Miguel Ketting, René Owen-Hughes, Tom Berger, Frédéric de Gier, Jan-Willem Grunwald Kadow, Ilona Marín, Oscar Khakh, Baljit Oxenius, Annette Bertolotti, Anne De Visser, Karin Guse, Annika Marine, Khor, Chiea Chuen Bertrand, Edouard Del Bene, Filippo Gyrd-Hansen, Mads Jean-Christophe Klaholz, Bruno P Bettencourt-Dias, Del Pozo, Miguel Marques, Ana Claudia Klose, Robert Palková, Zdena Mónica Delledonne, Massimo H Marques-Bonet, Tomas Knoblich, Jürgen Palmer, Ruth Blanpain, Cédric Dessen, Andrea Marston, Adèle Hajkova, Petra Köhler, Claudia Pasero, Philippe Blázquez, Miguel Dessimoz, Christophe Martens, Sascha Hajnal, Alex Komander, David Pasini, Diego Bochtler, Matthias Dickson, Barry Martin, Sophie Halic, Mario Kondrashov, Fyodor Passmore, Lori Boulton, Simon Dominguez, María Martín-Bermudo, María Hanna, Jacob Konieczny, Igor Peeper, Daniel Bousso, Philippe Donaldson, Anne Dolores Hardingham, Giles Koszul, Romain Pellizzoni, Livio Boutros, Michael Drew, David Martín-Serrano, Juan Harkany, Tibor Kraft, Claudine Peracchi, Alessio Briscoe, James Dutzler, Raimund Martinez, Javier Hassan, Bassem Kudla, Grzegorz Perrakis, Anastassis Brodin, Priscille Más, Paloma Haucke, Volker Kulathu, Yogesh Peters, Jan-Michael Broz, Petr Mathieu, Olivier Helariutta, Ykä Kunji, Edmund Mattevi, Andrea Peters, Antoine Buganim, Yosef Helms, Volkhard

76 EMBO Young Investigators EMBO facts & figures 2016 | www.embo.org EMBO Young Investigators 2000 – 2016 (continued)

Petronczki, Mark Schulze, Almut Trumpp, Andreas Philpott, Dana Schwappach, Blanche Tsiantis, Miltos Picotti, Paola Scorrano, Luca Tuschl, Thomas Pierre, Philippe Segal, Eran Pilpel, Yitzhak Selbach, Matthias U Plachta, Nicolas Seoane, Joan Uhlmann, Frank Poirazi, Panayiota Settembre, Carmine Ulitsky, Igor Polo, Simona Shcherbata, Halyna Ulrich, Helle Posas, Francesc Silva-Santos, Bruno Ungermann, Christian Potente, Michael Simons, Mikael Prud’homme, Benjamin Sirajuddin, Minhajuddin V van Aalten, Daan R So, Eric Sorek, Rotem Van den Ackerveken, Radtke, Freddy Sourjik, Victor Guido Ralser, Markus Soutoglou, Evi van der Goot, Gisou Rancati, Giulia Spahn, Christian van Steensel, Bas Reddy, Akhilesh Spang, Anne Vannini, Alessandro Rehwinkel, Jan Sprecher, Simon Veening, Jan-Willem Reich , Ziv Stancheva, Irina Veldhoen, Marc Rescigno, Maria Stark, Alexander Vendruscolo, Michele Reversade, Bruno Stock, Daniela Vermot, Julien Ricci, Romeo Sträßer, Katja Verstrepen, Kevin Richards, Thomas Strick, Terence Vinkemeier, Uwe Rico, Beatriz Stumpf, Michael Viola, Antonella Rink, Jochen Suomalainen- Voinnet, Olivier Rizzoli, Silvio Wartiovaara, Anu Robinson, Robert Szabò, Ildikò W Roca-Cusachs, Pere Walden, Helen Rodriguez, Ivan T Walther, Tobias Rooijakkers, Suzan West, Steven Roska, Botond Tachibana-Konwalski, Wilson, Daniel Rouse, John Kikue Taipale, Jussi Wimmer, Ernst Tamagnone, Luca Wollert, Thomas S Tanaka, Tomoyuki Wutz, Anton Sablina, Anna Tanay, Amos Wyart, Claire Sahai, Erik Tapon, Nicolas Salecker, Iris Tarsounas, Madalena Y Sandberg, Rickard Tavernarakis, Nektarios Yanai, Itai Santos, Manuel Teichmann, Sarah Saudou, Frédéric Teixeira, Maria Teresa Z Schärer, Orlando Teleman, Aurelio Schedl, Andreas Telford, Maximilian Zarivach, Raz Schleper, Christa Tessmar-Raible, Kristin Zeeman, Samuel Schlötterer, Christian Thérond, Pascal Zegerman, Philip Schneitz, Kay Thery, Manuel Zernicka-Goetz, Magdalena Schnittger, Arp Thiele, Ines Zimmermann, Pascale Schnorrer, Frank Thompson, Barry Zuber, Johannes Schratt, Gerhard Tolar, Pavel Schübeler, Dirk Torres-Padilla, Schuh, Melina Maria-Elena Schuldiner, Maya Trouche, Didier

EMBO facts & figures 2016 | www.embo.org EMBO Young Investigators 77 EMBO Young Investigators: statistics Applications and awards 2007 – 2016 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Country Appl. Aw. Appl. Aw. Appl. Aw. Appl. Aw. Appl. Aw. Appl. Aw. Appl. Aw. Appl. Aw. Appl. Aw. Appl. Aw. Austria 2 1 1 0 2 0 1 0 0 0 2 2 3 1 8 3 8 0 4 3 Belgium 6 1 2 0 6 1 3 1 3 0 3 0 5 1 9 1 2 0 3 0 Croatia 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 1 0 0 0 Czech Republic 0 0 1 0 1 0 0 0 0 0 0 0 1 0 3 0 2 0 3 0 Denmark 2 0 1 0 0 0 2 0 5 1 1 0 4 3 2 0 4 0 6 0 Estonia 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 Finland 8 0 2 0 2 0 1 0 2 0 4 0 9 0 3 0 1 0 3 0 France 8 3 11 1 11 0 12 0 23 4 21 3 29 3 20 4 23 4 15 3 Germany 19 3 21 1 17 2 22 7 19 3 16 1 17 2 31 7 25 4 34 2 Greece 4 0 2 0 2 0 2 0 1 0 1 1 0 0 2 0 1 0 0 0 Cyprus 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 Hungary 0 0 3 0 1 0 0 0 0 0 1 0 1 0 0 0 1 0 0 0 Iceland 1 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 India 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22 1 Ireland 0 0 0 0 1 0 2 0 2 0 1 0 0 0 2 0 3 0 1 0 Israel 2 1 4 0 6 1 7 1 4 1 10 4 8 1 7 1 6 1 8 2 Italy 10 1 4 0 15 1 12 1 11 0 8 0 7 0 10 1 12 1 10 1 Luxembourg 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 Netherlands 5 1 7 0 7 1 7 1 6 1 13 1 11 1 7 0 6 1 9 1 Norway 0 0 0 0 0 0 0 0 1 0 3 0 2 0 2 0 0 0 0 0 Poland 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 Portugal 1 0 1 0 2 1 5 1 3 0 3 0 19 0 9 0 4 0 12 0 Singapore 0 0 0 0 0 0 0 0 0 0 4 1 1 1 3 0 6 2 3 1 Slovakia 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 Slovenia 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Spain 18 3 12 1 8 0 14 3 27 0 23 1 28 3 21 1 11 1 16 1 Sweden 14 1 3 0 3 1 4 0 8 1 7 1 6 1 11 0 7 1 6 0 Switzerland 4 0 5 2 11 6 11 1 11 3 10 2 7 1 10 3 11 5 9 2 Taiwan 0 0 0 0 0 0 0 0 0 0 0 0 1 0 4 1 3 0 1 0 Turkey 2 0 3 0 1 0 0 0 1 0 4 0 0 0 1 0 2 0 1 0 United Kingdom 26 3 32 7 24 3 32 5 34 8 22 5 29 5 33 4 33 3 47 8 Others 0 0 0 0 0 0 0 0 0 0 0 0 2 0 2 0 0 15 144 0 Total 132 18 116 12 123 17 137 21 164 22 160 22 192 23 202 27 174 23 400 24

Female 37 3 32 2 34 4 39 3 57 8 57 8 59 5 64 7 64 8 65 9 Male 95 15 84 10 89 13 98 18 107 14 103 14 133 18 138 20 110 15 149 16

78 EMBO Young Investigators EMBO facts & figures 2016 | www.embo.org EMBO Young Investigator Lectures 2016 Young Investigator Conference Location Date Alexander Stark Keystone Symposia: Enhancer Malfunction in Cancer US-Santa Fe 21 – 24 February Pavel Tolar Keystone Conference: Antibodies as Drugs CA-Whistler 6 – 10 March Shalev Itzkovitz Keystone Symposia – Islet Biology: From Cell Birth to Death US-Keystone 13 – 17 March Niels Mailand Responses to DNA damage: from molecule to disease NL-Egmond aan Zee 17 – 22 April Gaëlle Legube Responses to DNA damage: from molecule to disease NL-Egmond aan Zee 17 – 22 April Jacqueline Jacobs Responses to DNA damage: from molecule to disease NL-Egmond aan Zee 17 – 22 April François Leulier Mechanisms of Insect Nutritional Homeostasis DE-Bonn 1 – 4 May Kristin Tessmar-Raible SRBR 2016: 15th biennial conference of the Society for US-Palm Harbor, Florida 21 – 25 May Research on Biological Rhythms Petra Hajkova Gordon Research Conference: Chromatin Structure and CH-Les Diablerets 22 – 27 May Function Anja Groth Gordon Research Conference: Chromatin Structure and CH-Les Diablerets 22 – 27 May Function Anna Sablina EMBO Conference: Cellular Signalling and Cancer Therapy HR-Cavtat 27 – 31 May Petr Broz Conference on Molecular Mechanisms of Inflammation NO-Trondheim 30 May – 2 June Yuki Nakamura International Workshop on Plant Membrane Biology US-Annapolis 5 – 10 June Thomas Wollert Keystone Conference: Autophagy: Molecular and CA-Whistler 5 – 9 June Physiological Mechanisms Frank Schnorrer Frontiers in Myogenesis: Molecular Mechanisms US-Pacific Grove 6 – 11 June Modulating Skeletal Muscle Development and Homeostasis in Health and Disease Gad Asher 2016 Lipoprotein Metabolism Gordon Research Conference US-Waterville Valley 12 – 17 June Yogesh Kulathu FASEB Conference Ubiquitin and Cellular Regulation US-Big Sky Resort, 12 – 17 June Florent Ginhoux Microglia in the brain, Keystone symposia US-Keystone 12 – 16 June Pedro Carvalho Storage and breakdown of fatty acids FI-Kirkkonummi 13 – 15 June Thomas Richards Gordon Research Conference: Cellular & Molecular Fungal US-Plymouth 19 – 23 June Biology Matteo Iannacone Immunochemistry & Immunobiology Gordon Research IT-Il Ciocco 19 – 23 June Conference Manuel Thery A Biochemical Society/European Cytoskeletal Forum GB-Cambridge 20 – 23 June meeting: Cell Adhesion and migration. Melina Schuh Chromosome Segregation and Aneuploidy IE-Galway 25 – 29 June Nicolas Plachta Janelia Conferences Imaging Mouse Development US-Ashburn 27 – 30 June Yuki Nakamura 22nd International Symposium on Plant Lipids (ISPL) DE-Göttingen 3 – 8 July

EMBO facts & figures 2016 | www.embo.org EMBO Young Investigators 79 EMBO Young Investigator Lectures 2016 Young Investigator Conference Location Date Melike Lakadamyali Gordon Research Conference: Single Molecule Approaches CN-Hong Kong 3 – 8 July to Biology Lori Passmore FASEB conference: Post-transcriptional control of gene PT-Lisbon 10 – 15 July expression: mechanisms of RNA decay Frank Schnorrer IMM Lisbon seminar PT-Lisbon 10 – 12 July Andrew Carter Muscle and Molecular Motors Gordon Research Conference US-West Dover 17 – 22 July Renata Basto 12th International Congress of Cell Biology (Exploring CZ-Prague 21 – 25 July Cellular Structure and Function) Petra Hajkova 12th International Congress of Cell Biology (Exploring CZ-Prague 21 – 25 July Cellular Structure and Function) Claus Maria Azzalin 12th International Congress of Cell Biology (Exploring CZ-Prague 21 – 25 July Cellular Structure and Function) Anja Groth 2016 Genomic Instability Gordon Research Conference CN-Hong Kong 24 – 29 July Gaëlle Legube 2016 Genomic Instability Gordon Research Conference CN-Hong Kong 24 – 29 July Lori Passmore 80th Harden Conference: Machines on Genes IV – GB-Macclesfield 31 July – 5 August Mechanisms of Actions of Large Macromolecular Machines on Genes Across Biological Scales Alessandro Vannini 80th Harden Conference: Machines on Genes IV – GB-Macclesfield 31 July – 5 August Mechanisms of Actions of Large Macromolecular Machines on Genes Across Biological Scales Isabelle Mansuy FEBS/EMBO Chromatin and the Environment Lecture GR-Spetses 4 August Course Brian Luke EMBO Workshop: Molecular mechanisms of ageing and GR-Spetses 16 – 24 August regeneration - From pluripotency to senescence Marek Basler 16th International Symposium on Microbial Ecology CA-Montreal 21 – 26 August (ISME16) François Leulier EMBO| FEBS Lecture Course, the new GR-Spetses 24 August – 1 September Maya Schuldiner EMBO Workshop: Organelle contact sites: Intracellular IT-Sardinia 15 – 18 Septmeber communication and role in disease Philip Zegerman EMBO Workshop: Nuclear Function and Cell Fate Choice GR-Kyllini 18 – 22 September Frank Schnorrer 30th French Drosophila meeting/DROSO2016 FR-Grasse 27 – 30 September Jacob Hanna Molecular Life of Stem Cell SI-Ljubljana 30 September – 1 October Anja Groth FEBS Workshop on Chromatin Proteomics GR-Heraklion 3 – 9 October Halyna Shcherbata EIE Symposium: The Complex Life of mRNA DE-Heidleberg 5 – 8 October

80 EMBO Young Investigators EMBO facts & figures 2016 | www.embo.org EMBO Young Investigator Lectures 2016 Young Investigator Conference Location Date Claudine Kraft 6th Annual Scientific Days on Autophagy FR-Bordeaux 12 – 14 October Julien Vermot Mechanical forces in physiology and disease ES-Madrid 4 – 5 November Jochen Rink Joint Events of “the 22nd International Conference of JP-Okinawa 15 – 19 November Zoology” and “the 87th Meeting of Zoological Society of Japan” Paola Picotti 18th EMBL PhD Symposium DE-Heidelberg 17 – 19 November Jan-Willem Veening EMBO Conference on Bacterial Morphogenesis, Survival IN-Thiruvananthapuram 27 November – 1 and Virulence: Regulation in 4D December Marek Basler EMBO Conference on Bacterial Morphogenesis, Survival IN-Thiruvanathapuram 27 November – 1 and Virulence: Regulation in 4D December

EMBO facts & figures 2016 | www.embo.org EMBO Young Investigators 81 EMBO Installation Grants

www.embo.org/funding-awards/installation-grants [email protected]

EMBO Installation Grants, launched in 2006, strengthen science by funding researchers to Gerlind Wallon relocate and establish laboratories in one of the participating member states of Croatia, Czech Programme Manager Republic, Estonia, Poland, Portugal, and Turkey. Awardees are closely integrated into the Young Investigator network, helping them to build reputations in the European scientific community.

EMBO Installation Grant Recipients 2016 Name Nationality Moving from Moving to Research interest Jaan-Olle Andressoo Estonian University of Helsinki, FI Tallinn Institute of Technology, EE Gene knock-up via 3’UTR targeting to treat Parkinson’s disease Claus Maria Azzalin Italian Institute of Biochemistry, ETH Institute of Molecular Medicine, Telomeres, cancer and aging Zurich, CH Lisbon, PT Murat Alper Cevher Turkish Rockefeller University, NY, US Bilkent University, Ankara, TR Characterization of mediator-estrogen receptor interaction Rafal Ciosk Swiss Friedrich Miescher Institute for Institute of Bioorganic Chemistry, Cell fate plasticity in development and Biomedical Research, Basel, CH Poznan, PL tissue homeostasis Catarina Homem* Portuguese Chronic Diseases Research Chronic Diseases Research Center Temporal and metabolic regulation of Center from Nova Medical School from Nova Medical School (CEDOC- stem cells. (CEDOC-NMS|FCM-UNL), PT NMS|FCM-UNL), PT Abdullah Kahraman German Institute of Molecular Life Sabanci University, Istanbul, TR Non-coding cancer driver mutations in Sciences, University of Zurich, CH isoform networks Vladimír Varga Czech University of Oxford, UK Institute of Molecular Genetics, Construction of the eukaryotic flagellum ASCR, Prague, CZ Piotr Ziolkowski Polish University of Cambridge, Adam Mickiewicz University, Crossover control in plants Cambridge, UK Poznan, PL

* Replaced Sonia Melo, selected 2015

82 EMBO Installation Grants EMBO facts & figures 2016 | www.embo.org EMBO Courses & Workshops

www.embo.org/funding-awards/courses-workshops [email protected]

The EMBO Courses & Workshops Programme funds high-quality meetings and provides scientists Anne-Marie Glynn and at all career stages with networking and training opportunities. The application and selection Gerlind Wallon Programme Manager processes ensure that the latest developments in science are reflected in the programme.

EMBO Courses | Workshops | Conferences | Symposia 2016 Title Organizer Location Dates Practical Courses Metabolomics bioinformatics for life scientists R. Salek UK-Cambridge 14 – 19 February EMBC Member States Advanced optical microscopy B. Amos UK-Plymouth 6 – 16 April Characterization of post-translational M.R. Larsen DK-Odense 7 – 14 April modifications Single cell gene expression analysis A. Ståhlberg DE-Heidelberg 11 – 16 April In vivo plant imaging A. Maizel DE-Heidelberg 24 April – 1 May Bioinformatics and genome analyses F. Tekaia TR-Izmir 2 – 14 May Computational molecular evolution A. Stamatakis GR-Heraklion 8 – 19 May Structural characterization of macromolecular C. Petosa FR-Grenoble 21 – 27 May complexes Non-neuronal optogenetics: From design S. De Renzis DE-Heidelberg 29 May – 4 June to application in cell signalling and tissue morphogenesis Computational analysis of protein-protein Z. Dosztányi HU-Budapest 30 May – 4 June interactions: Sequences, networks and diseases Fluorescence microscopy methods to study M. Tramier FR-Rennes 6 – 11 June protein-protein interactions in living cells Regulatory small and long ncRNAs: Durat et V. Benes IT-Trento 11 – 17 June lucet Advanced methods of electron microscopy in J. Nebesarova CZ-České Budějovice 14 – 24 June cell biology : Genomes to systems P. Bork DE-Heidelberg 19 – 23 June 3D developmental imaging G. Martins PT-Oeiras 1 – 9 July Integrative modelling of biomolecular A. Bonvin ES-Barcelona 4 – 9 July interactions Correlative light electron microscopy P. Verkade UK-Bristol 10 – 15 July

EMBO facts & figures 2016 | www.embo.org EMBO Courses & Workshops 83 EMBO Courses | Workshops | Conferences | Symposia 2016 Title Organizer Location Dates Practical Courses Multidimensional NMR in structural biology C. Griesinger DE-Joachimsthal 10 – 15 July EMBC Member States Light sheet microscopy P. Tomancak DE-Dresden 15 – 26 August (continued) Cryo-electron microscopy and 3D image C. Sachse DE-Heidelberg 28 August – processing 5 September Analysis of high-throughput sequencing data G. Rustici UK-Cambridge 5 – 10 September Protein expression, purification, and R. Meijers DE-Hamburg 12 – 20 September characterization (PEPC10) New approaches to study ubiquitin and D. Komander IT-Alghero 17 – 24 September ubiquitin-like modifications Non-coding RNA in infection J. Vogel DE-Würzburg 18 – 24 September Targeted NGS in patients with cancer, G. Wator PL-Krakow 19 – 23 September mendelian or complex diseases Modelling cellular processes in space and time F. Nedelec FR-Hyères 15 – 22 October High throughput microscopy for systems R. Pepperkok DE-Heidelberg 17 – 23 October biology Solution scattering from biological D. Svergun DE-Hamburg 17 – 24 October macromolecules Biomolecular interaction analysis 2016: From F. Silva PT-Porto 7 – 11 November molecules to cells Targeted proteomics: Experimental design and E. Sabidó ES-Barcelona 13 – 18 November data analysis

Practical Courses Phylogenetics in the '-omics' era M. O'Connell PE-Iquitos 10 – 17 January Non-EMBC Member States

Workshops Systems biology of non-coding RNAs I. Ulitsky IL-Rehovot 8 – 11 February EMBC Member States Multiple functions of piRNAs and PIWI proteins M. Simonelig FR-Montpellier 6 – 9 April Neural control of metabolism and eating A. Domingos PT-Cascais 5 – 7 May behaviour Molecular biology of mitochondrial gene M. Ott SE-Bro 23 – 26 May expression Mechanisms of neuronal remodelling T. Misgeld DE-Seeon 5 – 9 June RNA structure meets function K. Petzold SE-Stockholm 12 – 15 June Dendritic anatomy, molecules and function P. Poirazi GR-Heraklion 18 – 21 June

84 EMBO Courses & Workshops EMBO facts & figures 2016 | www.embo.org EMBO Courses | Workshops | Conferences | Symposia 2016 Title Organizer Location Dates Workshops Membrane fusion in health and disease F.A. Rey FR-Paris 20 – 24 June EMBC Member States New model systems for early land plant F. Berger AT-Vienna 22 – 24 June (continued) evolution Chromosome segregation and aneuploidy K. Sullivan IE-Galway 25 – 29 June Advanced proteomics B. Kuster IT-Varna 31 July – 6 August Molecular mechanisms of ageing and C. Englert GR-Spetses 16 – 24 August regeneration: From pluripotency to senescence Bacterial cell division: Orchestrating the ring O. Massidda CZ-Prague 14 – 17 September cycle Cell size regulation M. Fainzilber DE-Joachimsthal 14 – 18 September Organelle contact sites: Intracellular L. Scorrano IT-Domus de Maria 15 – 18 September communication and role in disease Nuclear function and cell fate choice S. Taraviras GR-Kyllini 18 – 22 September The modularity of signalling proteins and B. Mayer AT-Seefeld in Tirol 20 – 25 September networks Glycosylation in the Golgi complex S. Parashuraman IT-Vico Equense 24 – 28 October Transducing glycan information into function: L. Johannes FR-Mandelieu-la- 27 November – Lessons from galectins Napoule 1 December

Workshops AIDS-related mycoses T. Bicanic ZA-Cape Town 13 – 15 July EMBC Cooperation Partner

Workshops Actualizations in membrane trafficking in M.P. Marzolo CL-La Serena 4 – 9 September Non-EMBC Member health and disease States

Conferences From host genomes to microbiome: Immunity I. Amit IL-Rehovot 14 – 16 February EMBC Member States in the genomic era Visualizing biological data (VIZBI 2016) S. O'Donoghue DE-Heidelberg 9 – 11 March Telomeres, telomerase and disease R. Wellinger BE-Liege 26 April – 1 May Imaging the brain J. Wlodarczyk PL-Warsaw 18 – 21 May Cellular signalling and cancer therapy J.L. Bos HR-Cavtat 27 – 31 May Gene transcription in yeast: From chromatin to F.C. Holstege ES-Sant Feliu de 11 – 16 June RNA and back Guixols

EMBO facts & figures 2016 | www.embo.org EMBO Courses & Workshops 85 EMBO Courses | Workshops | Conferences | Symposia 2016 Title Organizer Location Dates Conferences The biochemistry and chemistry of biocatalysis: R. Wierenga FI-Oulu 12 – 15 June EMBC Member States From understanding to design (continued) Problems of listeriosis (ISOPOL XIX) P. Cossart FR-Paris 14 – 17 June Molecular and developmental biology of S. Bray GR-Chania, Crete 19 – 25 June Drosophila Ribosome structure and function 2016 M. Yusupov FR-Strasbourg 6 – 10 July Viruses of microbes 2016 M. Clokie UK-Liverpool 18 – 22 July The nitrogen nutrition of plants: Nitrogen 2016 A. Gojon FR-Montpellier 22 – 26 August Chemical biology 2016 C. Schultz DE-Heidelberg 31 August – 3 September Lymphocyte antigen receptor signalling C.T. Baldari IT-Pontignano 3 – 7 September Wnt meeting 2016 V. Bryja CZ-Brno 14 – 17 September The molecular and cellular basis of P. Ferretti IT-Paestum 17 – 21 September regeneration and tissue repair Tuberculosis 2016: Interdisciplinary research R. Brosch FR-Paris 19 – 23 September on tuberculosis and pathogenic mycobacteria Retinal proteins P. Hegemann DE-Potsdam 2 – 7 October Translational research in cancer cell A. Carracedo ES-Bilbao 4 – 6 October metabolism Cilia 2016 R. Roepman NL-Amsterdam 4 – 7 October Experimental approaches to evolution and L. Steinmetz DE-Heidelberg 19 – 22 October ecology using yeast and other model systems Structure and function of the endoplasmic P. Carvalho ES-Girona 23 – 27 October reticulum From functional genomics to systems biology E. Furlong DE-Heidelberg 12 – 15 November Molecular machines: Integrative structural and D. Panne DE-Heidelberg 20 – 23 November molecular biology Innate lymphoid cells – 2016 C. Romagnani DE-Berlin 30 November – 2 December

Conferences Bacterial morphogenesis, survival and S. Radhakrishnan IN- 27 November – Associate EMBC virulence: Regulation in 4D Thiruvananthapuram 1 December Member State

86 EMBO Courses & Workshops EMBO facts & figures 2016 | www.embo.org EMBO Courses | Workshops | Conferences | Symposia 2016 Title Organizer Location Dates EMBO | EMBL A new age of discovery for aquatic C. Bowler DE-Heidelberg 26 – 29 January Symposium microeukaryotes EMBC Member States Tumour microenvironment and signalling A.J. Berns DE-Heidelberg 3 – 6 April New model systems for linking evolution and D. Weigel DE-Heidelberg 8 – 11 May ecology Microtubules: From atoms to complex systems C. Janke DE-Heidelberg 29 May – 1 June Innate immunity in host-pathogen interactions F. Randow DE-Heidelberg 26 – 29 June Actin in action: From molecules to cellular P. Lénárt DE-Heidelberg 7 – 10 September functions The complex life of mRNA A. Ephrussi DE-Heidelberg 5 – 8 October Organoids: Modelling organ development and J. Knoblich DE-Heidelberg 12 – 15 October disease in 3D culture

EMBO | FEBS Lecture Chromatin and the environment A.G. Ladurner GR-Spetses 8 – 14 August Courses The new microbiology P. Cossart GR-Spetses 24 August – EMBC Member States 1 September

EMBO Global Structural and biophysical methods for D. Svergun KR-Suwon 19 – 26 June Exchange Lecture biological macromolecules in solution Courses Small brains, big ideas J. Ewer CL-Las Cruces 10 – 19 November Non-EMBC Member States

EMBO facts & figures 2016 | www.embo.org EMBO Courses & Workshops 87 Laboratory Management Courses 2016 (30 courses given to 478 scientists) Course participants Organizer Location Dates EMBO Laboratory Female Scientists A. Glynn & M. Cairns DE-Leimen 8 – 10 June Management Female Scientists A. Glynn & M. Cairns DE-Leimen 14 – 16 September Courses* Group Leaders A. Glynn & M. Cairns DE-Leimen 1 – 4 February Group Leaders A. Glynn & M. Cairns DE-Leimen 7 – 10 March Group Leaders A. Glynn & M. Cairns DE-Leimen 11 – 14 April Group Leaders A. Glynn & M. Cairns DE-Leimen 9 – 12 May Group Leaders A. Glynn & M. Cairns DE-Leimen 12 – 15 July Group Leaders (external course) A. Glynn & M. Cairns US-Cambridge, MA 26 – 29 September Group Leaders A. Glynn & M. Cairns DE-Leimen 10 – 13 October Group Leaders A. Glynn & M. Cairns DE-Leimen 7 – 10 November Group Leaders (external course) A. Glynn & M. Cairns IE-Dublin 15 – 17 November Group Leaders A. Glynn & M. Cairns DE-Leimen 14 – 17 November Group Leaders (external course) A. Glynn & M. Cairns UK-Cambridge 21 – 24 November Group Leaders (external course) A. Glynn & M. Cairns UK-Cambridge 28 November – 1 December Group Leaders A. Glynn & M. Cairns DE-Leimen 5 – 8 December Postdocs A. Glynn & M. Cairns DE-Leimen 26 – 28 January Postdocs A. Glynn & M. Cairns DE-Leimen 16 – 18 February Postdocs A. Glynn & M. Cairns DE-Leimen 14 – 16 March Postdocs A. Glynn & M. Cairns DE-Leimen 29 – 31 March Postdocs A. Glynn & M. Cairns DE-Leimen 19 – 21 April Postdocs A. Glynn & M. Cairns DE-Leimen 3 – 5 May Postdocs A. Glynn & M. Cairns DE-Leimen 30 May – 1 June Postdocs A. Glynn & M. Cairns DE-Leimen 6 – 8 June Postdocs (external course) A. Glynn & M. Cairns NL-Utrecht 14 – 16 June Postdocs A. Glynn & M. Cairns DE-Leimen 20 – 22 June Postdocs (external course) A. Glynn & M. Cairns IL-Rehovot 19 – 21 September Postdocs A. Glynn & M. Cairns DE-Leimen 25 – 27 October Postdocs A. Glynn & M. Cairns DE-Leimen 2 – 4 November Postdocs A. Glynn & M. Cairns DE-Leimen 22 – 24 November Postdocs A. Glynn & M. Cairns DE-Leimen 29 November – 1 December

*administered by the Gesellschaft zur Förderung der Lebenswissenschaften Heidelberg GmbH

88 EMBO Laboratory Management Courses EMBO facts & figures 2016 | www.embo.org EMBO Women in Science

www.embo.org/science-policy/women-in-science [email protected]

EMBO monitors gender balance in all of its activities and develops initiatives to counteract Gerlind Wallon imbalances and to raise awareness of issues facing female scientists as their careers advance. An Manager annual award highlights major contributions of female researchers to the life sciences.

Participation of women in EMBO activities: Statistics EMBO Membership (including Associate Members) EMBO Courses & Workshops 2011 – 2016 Year Total number of members % Women (including EMBO | EMBL Symposia, EMBO | FEBS Lecture Courses, 2002 1126 13 EMBO Conference Series, EMBO Global Exchange Lecture Courses, 2003 1162 13 EMBO Practical Courses, EMBO Workshops) 2004 1191 14 Year % women % female speakers 2005 1223 14 2011 49 27 2006 1271 14 2012 47 29 2007 1305 14 2013 46 30 2008 1357 14 2014 49 32 2009 1413 15 2015 49 35 2010 1461 15 2016* 49 35 2011 1492 15 2012 1532 16 *2016 data represents 72% of the events i.e. 65/90 of the total 2013 1567 16 number of events 2014 1657 17 2015 1695 17 2016 1728 18

EMBO facts & figures 2016 | www.embo.org EMBO Women in Science 89 Participation of women in EMBO activities: Statistics EMBO Short-Term Fellowships Applications % Awards % Success rate % 2010 Female applicants 230 55 126 58 55 Male applicants 191 45 93 42 49 Overall 421 219 52 2011 Female applicants 267 53 152 54 57 Male applicants 239 47 129 46 54 Overall 506 281 55 2012 Female applicants 317 54 165 53 52 Male applicants 268 46 147 47 55 Overall 585 312 53 2013 Female applicants 340 61 172 61 51 Male applicants 220 39 108 39 49 Overall 560 280 50 2014 Female applicants 322 59 167 59 52 Male applicants 226 41 117 41 52 Overall 548 284 52 2015 Female applicants 334 60 172 60 51 Male applicants 223 40 116 40 52 Overall 557 288 52 2016 Female applicants 362 59 201 57 56 Male applicants 256 41 149 43 58 Overall 618 350 57 2010 – 2016 Female applicants 2171 57 1155 57 53 Male applicants 1623 43 859 43 53 Overall 3794 2014 53

90 EMBO Women in Science EMBO facts & figures 2016 | www.embo.org Participation of women in EMBO activities: Statistics EMBO Long-Term Fellowships Applications % Awards % Success rate % 2010 Female applicants 802 48 123 45 15 Male applicants 866 52 152 55 18 Overall 1668 275 17 2011 Female applicants 748 46 103 38 14 Male applicants 885 54 165 62 19 Overall 1633 268 16 2012 Female applicants 739 48 115 47 16 Male applicants 816 52 132 53 16 Overall 1555 247 16 2013 Female applicants 793 48 77 42 10 Male applicants 852 52 108 58 13 Overall 1645 185 11 2014 Female applicants 742 45 86 35 12 Male applicants 906 55 161 65 18 Overall 1648 247 15 2015 Female applicants 773 50 118 47 15 Male applicants 776 50 134 53 17 Overall 1549 252 16 2016 Female applicants 733 47 67 39 9 Male applicants 828 53 103 61 12 Overall 1561 170 11 2010 – 2016 Female applicants 5330 47 689 42 13 Male applicants 5929 53 955 58 16 Overall 11259 1644 15

EMBO facts & figures 2016 | www.embo.org EMBO Women in Science 91 Participation of women in EMBO activities: Statistics EMBO Young Investigator Programme Applications % Awards % Success rate % 2010 Female applicants 39 28 3 14 8 Male applicants 98 72 18 86 18 Overall 137 21 15 2011 Female applicants 57 35 8 36 14 Male applicants 107 65 14 64 13 Overall 164 22 13 2012 Female applicants 57 36 8 36 14 Male applicants 103 64 14 64 14 Overall 160 22 14 2013 Female applicants 59 31 5 22 8 Male applicants 133 69 18 78 14 Overall 192 23 12 2014 Female applicants 64 32 7 26 11 Male applicants 138 68 20 74 14 Overall 202 27 13 2015 Female applicants 64 37 8 35 13 Male applicants 110 63 15 85 14 Overall 174 23 13 2016 Female applicants 65 30 9 36 14 Male applicants 149 70 16 64 11 Overall 214 25 12 2010 – 2016 Female applicants 405 33 48 29 12 Male applicants 838 67 115 71 14 Overall 1243 163 13

92 EMBO Women in Science EMBO facts & figures 2016 | www.embo.org Participation of women in EMBO activities: Statistics EMBO Installation Grants Applications % Awards % Success rate % 2010 Female applicants 11 32 3 43 27 Male applicants 23 68 4 57 17 Overall 34 7 21 2011 Female applicants 8 30 3 43 38 Male applicants 19 70 4 57 21 Overall 27 7 26 2012 Female applicants 11 28 1 10 9 Male applicants 29 73 9 90 31 Overall 40 10 25 2013 Female applicants 20 31 2 33 10 Male applicants 45 69 4 67 9 Overall 65 6 9 2014 Female applicants 27 39 2 25 7 Male applicants 42 61 6 75 14 Overall 69 8 12 2015 Female applicants 27 31 3 33 11 Male applicants 59 69 6 67 10 Overall 86 9 10 2016 Female applicants 19 28 1 14 5 Male applicants 50 72 6 86 12 Overall 69 7 10 2010 – 2016 Female applicants 123 32 15 28 12 Male applicants 267 68 39 72 15 Overall 390 54 14

EMBO facts & figures 2016 | www.embo.org EMBO Women in Science 93 EMBO Gold Medal

www.embo.org/funding-awards/gold-medal [email protected]

The EMBO Gold Medal is awarded annually to young scientists for outstanding contributions to the life sciences in Europe.

EMBO Gold Medalists 1986 – 2016

1986 John Tooze Heidelberg, DE 1998 Adriano Aguzzi Zurich, CH 2009 Gold Medal 2009 revoked in 1987 Barbara Pearse Cambridge, UK 1999 Konrad Basler Zurich, CH January 2016 1988 Antonio Lanzavecchia Basel, CH 2000 Christof Niehrs Heidelberg, DE 2010 Jason W. Chin London, UK 1989 Hugh Pelham Cambridge, UK Daniel St. Johnston Cambridge, UK 2011 Simon Boulton London, UK 1990 Erwin Wagner Vienna, AT 2001 Matthew Freeman Cambridge, UK 2012 Jirˇí Friml Ghent, BE 1991 Patrick Stragier Paris, FR 2002 Amanda Fisher London, UK 2013 Thijn Brummelkamp Amsterdam, NL 1992 Carl-Henrik Heldin Uppsala, SE 2003 Anthony Hyman Dresden, DE 2014 Sophie Martin Lausanne, CH 1993 Jim Smith London, UK 2004 María Blasco Madrid, ES 2015 Ido Amit Rehovot, IL 1994 Paolo Sassone-Corsi Strasbourg, FR 2005 Dario Alessi Dundee, UK Cambridge, UK 2016 Richard Benton Lausanne, CH 1995 Richard Treisman London, UK 2006 Frank Uhlmann London, UK Ben Lehner Barcelona, ES 1996 Enrico Coen Norwich, UK 2007 Jan Löwe Cambridge, UK 1997 Dirk Görlich Heidelberg, DE 2008 James Briscoe London, UK

94 EMBO Gold Medal EMBO facts & figures 2016 | www.embo.org EMBO Keynote Lectures

www.embo.org/funding-awards/lecture-grants [email protected]

Every year, EMBO Members are funded to present keynote lectures at international scientific Anne-Marie Glynn and meetings. Keynote lectures raise awareness of EMBO activities, support members in their Gerlind Wallon Programme Manager collaborations with scientists from associated fields and promote European science worldwide.

EMBO Keynote Lectures 2016 Name Lecture Title Location Date Keynote Lectures Christopher M. Dobson 60th Annual Meeting of the Society of DE-Muenster 17 – 20 February EMBC Member States Thrombosis and Haemostasis Research Hans Wolf-Watz Bacterial Type III Secretion Systems DE-Tübingen 3 – 5 April Josef Jiricny 10th Quinquennial Conference on NL-Egmond aan Zee 17 – 22 April Responses to DNA damage: From Molecule to Disease Luke O’Neill International Conference on Molecular NO-Trondheim 30 May – 3 June Mechanisms of Inflammation Daniel Peeper Cellular Senescence: From Molecular IL-Rehovot 3 – 6 July Mechanisms to Therapeutic Opportunities Jörg Vogel FASEB Summer Research Conference PT-Lisbon 10 – 15 July on Post-transcripitonal Control of Gene Expression: Mechanisms of RNA decay Elena Conti Machines on Genes IV - Mechanisms of UK-Cheshire 31 July – 4 August Actions of Large Macromolecular Machines on Genes Across Biological Scales Isabelle Mansuy EMBO-FEBS Lecture Course on Chromatin GR-Spetses Island 8 – 14 August and the Environment - Spetses Summer School Maria Antonietta De FEBS Advanced Course on Lipid-protein GR-Spetses Island 1 – 8 September Matteis Interactions and Organelle Function Jacques Pouysségur 41st FEBS Congress 'Molecular and TR-Aydın 3 – 8 September Systems Biology for a Better Life' Margaret S. Robinson 2nd International Meeting 'Building the FR-Paris 28 – 30 September Cell' Fiona M. Watt EACR Conference Series - Goodbye Flat DE-Berlin 2 – 5 October Biology : Models, Mechanisms and Microenvironment

EMBO facts & figures 2016 | www.embo.org EMBO Keynote Lectures 95 EMBO Keynote Lectures 2016 Name Lecture Title Location Date Keynote Lectures Anne C. Ferguson-Smith Genomic Imprinting, and IT-Erice 2 – 7 October EMBC Member States Physiological Functions (continued) Eileen Furlong 2nd Danube Scientific Conference on HU-Budapest 5 – 8 October Epigenetics Jonathan Flint iMed Conference® 8.0 Lisbon 2016 PT-Lisbon 13 – 16 October Joel L. Sussman XVth International Symposium on FR-Marseille 16 – 20 October Cholinergic Mechanisms (XVth ISCM) Jürgen Knoblich World Congress of Psychiatric Genetics IL-Jerusalem 30 October – 2016: Bridging the Gap Between Genes, 4 November Brain Function and Psychiatry Stefano Piccolo CNIC Conference on 'Mechanical forces in ES-Madrid 4 – 5 November physiology and disease' Susan M. Gasser Transcription-Replication Crosstalk and FR-Roscoff 14 – 18 November Genome Instability Luis Serrano 18th EMBL PhD Symposium Life by DE-Heidelberg 17 – 19 November Numb3rs – Towards Quantitative Biology

Keynote Lectures Ian T. Baldwin How Being an Auto Mechanic Made Me a IN-Manesar Gurgaon 27 February – Associate EMBC Better Scientist 2 March Member State

Keynote Lectures Leif Andersson Avian Model Systems 9: A New Integrative TW-Taipei 28 – 31 March EMBC Cooperation Platform Partner

Keynote Lectures Dirk Görlich 41st Lorne Protein Conference on Protein AU-Lorne 7 – 11 February Non-EMBC Member Structure and Function States Detlef Weigel 2016 Lorne Genome Conference AU-Lorne 14 – 16 February Magdalena Götz Neurogenesis: Implications for Lifelong MX-Cancún 2 – 5 March Development and Disease Thomas F. Meyer FEBS Advanced Lecture Course: Current AM-Yerevan 21 – 26 March Advances in Pathogen Research Magdalena The 16th Hunter Cell Meeting AU-Lovedale 12 – 15 April Zernicka-Goetz Incorporating the 9th National Imaging Workshop Ben J.G. Scheres The Auxin2016 Conference CN-Sanya Haitang Bay 20 – 25 October

96 EMBO Keynote Lectures EMBO facts & figures 2016 | www.embo.org EMBO Keynote Lectures 2016 Name Lecture Title Location Date Keynote Lectures Gabriel Waksman The First Zing Conference on Protein US-Tampa 9 – 12 November Non-EMBC Member Secretion in Bacteria States Søren Brunak ​International Society for Computational AR-Buenos Aires 21 – 23 November (continued) Biology Latin America Conference ​(ISCB-LA)

EMBO facts & figures 2016 | www.embo.org EMBO Keynote Lectures 97 EMBO staff in Heidelberg under contract in 2016

Director Maria Leptin EMBO Director [email protected] Director’s Office Eilish Craddock Personal Assistant to EMBO Director [email protected] Luis Valente Project Officer [email protected]

EMBC and EMBO Council Gitta Bourke Administrator [email protected]

EMBO Membership Volker Wiersdorff Manager, EMBO Membership & Elections [email protected] Larisa Bulgatova Administrator [email protected]

Courses & Workshops Programme, Anne-Marie Glynn Programme Manager Global Activities and Luis Valente Project Officer [email protected] Plenary Lectures Joy Akinyi Administrator [email protected] courses_workshops @embo.org Aditya Kusuma Jati Web and Graphic Designer [email protected] Stephen Pewter Digital Communications Officer [email protected]

Fellowship Programme Andrea Hutterer Programme Manager [email protected] David del Alamo Programme Manager [email protected] Benardine Ngu Administrator, Finance & Fellowships [email protected] Larisa Bulgatova Admnistrator, Fellowships [email protected] Ingrid Busby Administrator, Short-Term Fellowships [email protected] Zsuzsanna O'Donoghue Administrator, Short-Term Fellowships Inga Strazda Administrator, Fellowships [email protected]

Science Policy Programme Michele Garfinkel Programme Manager [email protected] [email protected] Alessandra Bendiscioli Programme Officer [email protected]

Young Investigator Programme, Gerlind Wallon Programme Manager, EMBO Deputy Director [email protected] Installation Grants and Women Rachel Coulthard Programme Officer in Science Olena Steshenko Programme Officer [email protected] [email protected]

Administration & Finance Bernhard Huber Head, Administration & Finance [email protected] Seán Bourke Reception, Building Maintenance [email protected] Samuel Caddick* Project Coordinator, GFLW [email protected] Martin Cairns* Conference Officer Eva Portik Accounting Officer [email protected] Benardine Ngu Administrator, Finance & Fellowships [email protected]

EMBO Scientific Publications Bernd Pulverer Head of EMBO Scientific Publications [email protected] Thomas Lemberger Deputy Head of EMBO Scientific Publications [email protected]

* Employed by Gesellschaft zur Förderung der Lebenswissenschaften Heidelberg GmbH

98 EMBO staff in Heidelberg EMBO facts & figures 2016 | www.embo.org The EMBO Journal Bernd Pulverer Chief Editor [email protected] [email protected] Karin Dumstrei Senior Editor [email protected] Ieva Gailite Editor [email protected] Daniel Klimmeck Editor [email protected] Andrea Leibfried Editor [email protected] Anne Nielsen Editor [email protected] Fiona Panayi Editorial Assistant [email protected] Meryl Schneider Editorial Assistant [email protected] Gerlinde Schuster Editorial Assistant [email protected]

EMBOreports Holger Breithaupt Senior Editor [email protected] [email protected] Achim Breiling Editor [email protected] Barbara Pauly Senior Editor Martina Rembold Editor [email protected] Esther Schnapp Senior Editor [email protected] Elizabeth Corrao Editorial Assistant [email protected] Joel Maupin Editorial Assistant [email protected] Erica Wilfong Boxheimer Editorial Assistant [email protected]

EMBO Molecular Medicine Céline Carret Editor [email protected] [email protected] Roberto Buccione Editor [email protected] Gerlinde Schuster Editorial Assistant [email protected]

Molecular Systems Biology Thomas Lemberger Chief Editor [email protected] [email protected] Maria Polychronidou Editor [email protected]

Source Data Sara El-Gebali SourceData Biocurator Nancy George SourceData Biocurator

EMBO Marketing & Communications Tilmann Kiessling Head, Marketing & Communications [email protected] Annika Grandison Public Affairs & Communications Officer [email protected] Yvonne Kaul Communications Officer Sandra Krahl Senior Graphic Designer [email protected] Igor Jukic Graphic Design & Communications Assistant [email protected] Aditya Kusuma Jati Web and Graphic Designer Stephen Pewter Digital Communications Officer [email protected]

Information Support & Resources Volker Wiersdorff Head, Information Support & Resources [email protected] Kevin Fleming Web and Database Developer [email protected]

Initiative for Science in Europe (ISE) Wolfgang Executive Co-ordinator ISE [email protected] Eppenschwandtner

EMBO facts & figures 2016 | www.embo.org EMBO staff in Heidelberg 99

EMBO Editor Meyerhofstr. 1 Tilmann Kießling 69117 Heidelberg Production: Coordination, Germany layout, graphics, cover T +49 6221 8891 0 Sandra Krahl F +49 6221 8891 200 Photos [email protected] Marietta Schupp (EMBL Photolab) www.embo.org

European Molecular Biology Conference Meyerhofstr. 1 69117 Heidelberg Germany T +49 6221 8891 0 F +49 6221 8891 202 [email protected] embc.embo.org HIGHLIGHTS  CONTACT EMBO & EMBC

Membership  new members from  countries in Europe and eight EMBO Young Investigators Associate Members from China, Japan, Lithuania, Singapore and EMBO Installation Grants the United States were elected. EMBO Women in Science Fellowships Long-Term Fellowships opened for applications all year round EMBO Courses & Workshops and new eligibility criteria for Short-Term Fellowships were EMBO Keynote Lectures R Gerlind Wallon EMBO Scientific Publications I introduced. C H Programme Manager Bernd Pulverer A  Long-Term,  Short-Term and  Advanced Fellowships R Maria Leptin Deputy Director Head D were awarded. EMBO Director +     +     B BE E N 6 N TON 201 Young Investigators and Lithuania joined the Installation Grants scheme.

LE Installation Grants H N  Young Investigators and  Installation Grantees became part ER 2016 of the EMBO community. Science Policy EMBO co-organised a workshop on science advising in Europe. Eilish Craddock Personal Assistant to Science Policy Programme Manager Michele Gar nkel was EMBO Fellowships EMBO Scientific Publications the EMBO Director invited to represent EMBO on the European Commission’s Open David del Álamo Thomas Lemberger +     7th Science Policy Platform. Programme Manager Deputy Head The programme continued its work on research integrity, +     +     including presentations at European institutes and improve-

advancing the life sciences ments to the online training course. 2016 Courses & Workshops More than , participants attended  scienti c events. Mannheim  EMBO Laboratory Management Courses were held in GERMANY Heidelberg and at six research institutes worldwide. 10 – 13 September Administration & Finance EMBO Global Activities EMBO Communications The th EMBO Meeting in Mannheim concluded the meeting Bernhard Huber Luis Valente Tilmann Kießling series. Head Head Head +     +     +     Global Activities Malta and Lithuania become EMBC Member States. EMBO partners with the Wellcome Trust/DBT India Alliance to deliver three life science meetings per year in India. Awards The EMBO Gold Medal was awarded to Richard Benton and Ben Lehner. EMBC EMBO Membership & EMBO Council & Committees EMBO Science Policy Elections Fiona Watt received the FEBS | EMBO Women in Science Award. Gitta Bourke Michele Garfinkel Volker Wiersdorff EMBO Press EMBO Press extended its scooping protection policy to preprints. Administrator Programme Manager Head SourceData The SmartFigures lab application of SourceData was developed +     +     +     in collaboration with publishing house Wiley and launched at The EMBO Meeting.

Complete list of EMBO staff in Heidelberg on pages  . excellence in life sciences

Reykjavik Helsinki Oslo

EMBO facts & figures  Tallinn Stockholm Copenhagen Vilnius Dublin Amsterdam Berlin Warsaw London Brussels Prague Bratislava Paris Luxembourg Budapest Bern Vienna Ljubljana Zagreb

Rome Madrid Ankara Lisbon Athens Valletta Jerusalem

New Delhi

Singapore

EMBO facts & figures