44th Northeast Bioengineering Conference

March 28 – 30, 2018 Drexel University, Philadelphia, PA

Drexel University is a private research university with its main campus located in the University City neighborhood of Philadelphia, Pennsylvania, United States. It was founded in 1891 by Anthony J. Drexel, a noted financier and philanthropist. Founded as Drexel Institute of Art, Science, and Industry, it was renamed Drexel Institute of Technology in 1936, before assuming the name Drexel University in 1970. More than 26,000 students are enrolled in over 70 undergraduate programs and minors, more than 100 master’s and 40 graduate minors, doctoral, and professional programs at the university. Drexel’s cooperative education program (co-op) offers students the opportunity to gain up to 18 months of paid, full-time work experience in a field relevant to their undergraduate major or graduate degree program prior to graduation.

To learn more about co-op, visit drexel.edu/co-op

1 Welcome

44TH NORTHEAST BIOENGINEERING CONFERENCE Drexel University Philadelphia, PA

March 28-30, 2018

ORGANIZING COMMITTEE

CONFERENCE CHAIR FACULTY SEMINARS Ken Barbee Sriram Balasubramanian CONFERENCE CO-CHAIR Lin Han Katie von Reyn Andres Kriete Kara Spiller

FINANCE ABSTRACT REVIEW Clair King Ken Barbee PUBLIC RELATIONS & MEDIA Emad Boctor Steve Detofsky, David Myers Daniel Cortes LOCAL ARRANGEMENTS Andres Kriete Danielle Crocker Peter Lelkes Katie von Reyn Adrian Shieh DESIGN POSTER COMPETITION Anita Singh Joseph Sarver (Coordinator) Marek Swoboda Marek Swoboda Yinghui Zhong

2 Program at a Glance

WEDNESDAY, MARCH 28

11:00 Registration Open 12:00-2:00 Neuroengineering Faculty Seminar Katie von Reyn, Moderator 2:00-3:15 Undergraduate Design Poster Session I Organizers: Joseph Sarver, Marek Swoboda Biomedical Imaging and Image Processing, Biomedical Sensors, Cancer Technologies, Cardiovascular and Respiratory Systems Engineering, Computational Bioengineering, Device Technologies and Biomedical Robotics, Devices: Micro- and Nano-Bioengineering, Diagnostic Systems, Drug Delivery, Education in Biomedical Engineering. 3:15 – 3:45 Coffee Break 3:45 – 5:00 Undergraduate Design Poster Session II Organizers: Joseph Sarver, Marek Swoboda Cellular and Molecular Bioengineering, Neural Engineering, Immuno-Engineering, Orthopedic Engineering, Pediatric Bioengineering, Rehabilitation Engineering, Biomechanics/Mechanobiology, Tissue Engineering/3D Printing, Biomaterials, Other. 5:00-6:30 Welcoming Remarks Paul Brandt-Rauf and Ken Barbee Keynote – Start-Up Campus: How to Bring Your Scientific Discovery to a Successful Commercial Product. Michele Marcolongo. Drexel University Panel Discussion – Entrepreneurship in Academia, Industry and the Clinic Panelists: Brian Garvey, Justine Han, Michele Marcolongo, Gulyeter Serbest Moderators: Ken Barbee, Andres Kriete Design Award Presentations Jay Sarver and Paul Brandt-Rauf 6:30-8:00 Networking Reception

THURSDAY, MARCH 29

8:00 Registration Open 8:30-9:30 1. Biomaterials/Biomimetic 2. Biomedical Imaging and 3. Immuno- and Neuroengineering Materials Image Processing Chair: Katie von Reyn, Chair: Christopher Rock, Chair: Emad Boctor, Drexel University Children’s Hospital of Johns Hopkins University Philadelphia (CHOP) 9:30-10:30 Research Poster Session I Biomaterials, Cardiovascular and Respiratory Systems Engineering, Cellular and Molecular Bioengineering, Computational Bioengineering, Neural Engineering, Immunoengineering, Orthopedic Engineering, Pediatric Bioengineering, Rehabilitation Engineering, Tissue Engineering/3D Printing. 10:30-11:15 Keynote – Lymphatic Vessels in Inflammation and Cancer: New Roles in Immune Regulation and Implications for Immunotherapy. Melody Swartz, University of Chicago

3 Program at a Glance

11:15-1:15 Immunoengineering Faculty Seminar Kara Spiller, Moderator 1:15-2:30 Lunch 2:30-3:30 4. Tissue Engineering/ 5. Computational 6. Pediatric Bioengineering Functional Biomaterials Bioengineering Chair: Anita Singh, Chair: Peter Lelkes, Chair: Andres Kriete, Widener University Temple University Drexel University 3:30-4:30 Research Poster Session II Biomechanics/Mechanobiology, Biomedical Imaging and Image Processing, Biomedical Sensors, Cancer Technologies, Device Technologies and Biomedical Robotics, Devices: Micro- and Nano-Bioengineering, Diagnostic Systems, Drug Delivery, Education in Biomedical Engineering, Other. 4:30-6:30 Pediatric Bioengineering Symposium Sriram Balasubramanian, Moderator Co-hosted with Children’s Hospital of Philadelphia (CHOP) Keynote – Flaura K. Winston, CHOP

FRIDAY, MARCH 30

8:00 Registration Open 8:30-9:30 7. Biomechanics 8. Biomedical Sensors 9. Drug Delivery Chair: Daniel Cortes, Chair: Wan Shih, Chair: Margaret Wheatley, Penn State University Drexel University Drexel University 9:30-9:45 Coffee Break 9:45-10:45 10. Mechanobiology 11. Biomedical Devices 12. Orthopedic and Rehabilitation Chair: Adrian Shieh, Chair: Marek Swoboda, Engineering Drexel University Drexel University Chair: Sarah Gullbrand, University of Pennsylvania 10:45-11:00 Coffee Break 11:00-1:00 Mechanobiology Faculty Seminar Lin Han, Moderator 1:00 -1:30 Research Award Presentations, Conference Adjournment

4 Keynote Speakers

MELODY SWARTZ, PHD Melody A. Swartz is a Professor in the Institute of Molecular Engineering at the University of Chicago, where she holds the William B. Ogden Chair, as well as a joint appointment in the Ben May Department for Cancer Research. Her education was in Chemical Engineering, first with a BS from the Johns Hopkins University, and then a PhD from Massachusetts Institute of Technology. She undertook postdoctoral studies at Brigham & Women’s Hospital in Boston before starting in 1999 as an Assistant Professor at Northwestern University, jointly in the Departments of Biomedical Engineering and Chemical Engineering. In 2003, she was recruited to the Ecole Polytechnique Fédérale de Lausanne (EPFL), where she was promoted to Full Professor in the Institute of Bioengineering and the Swiss Institute for Experimental Cancer Research. Trained as a bioengineer, she uses quantitative approaches in immunobiology and physiology, including biotransport and biomechanics, to develop a deeper understanding of how the lymphatic system regulates immunity in homeostasis and disease, particularly in cancer and chronic inflammation. Her lab applies this knowledge to develop novel immunotherapeutic approaches in cancer, including lymph node-targeting vaccine approaches, as well as in vitro model systems that recapitulate relevant features of the 3D, perfused tumor microenvironment.

MICHELE MARCOLONGO, PHD, PE Michele Marcolongo is Department Head and Professor of Materials Science and Engineering at Drexel University. There, she has served as Senior Associate Vice Provost for Translational Research at Drexel University, Associate Dean of Intellectual Property for the College of Engineering and Associate Vice Provost for Research. Marcolongo’s field of research is biomaterials or materials that can be implanted into the body to replace diseased or damaged tissues. Specifically, she works on injectable biomaterials and macromolecules to replace and augment degenerated soft tissues. Marcolongo has co-founded three companies: the first, Gelifex, was sold to a major orthopaedics manufacturer and one company, Invisalert Solutions, is active presently. She is a fellow of the National Academy of Inventors, AIMBE and Alpha Sigma Mu. Marcolongo has authored a book, Academic Entrepreneurship: How to Bring Your Scientific Discovery to a Successful Commercial Product (Wiley 2017), a “how-to” on translating research from discovery to commercialization for academics. Marcolongo received her doctorate from the University of Pennsylvania, Philadelphia and had worked for GE and DuPont before joining Drexel University in 1997.

FLAURA WINSTON, MD, PHD Flaura Koplin Winston is the founder and Scientific Director of the Center for Injury Research and Prevention and Director of CChIPS at Children’s Hospital of Philadelphia. She holds the Distinguished Chairs in the Department of Pediatrics. Flaura Koplin Winston is a board-certified pediatrician, a doctorally-trained engineer, and a public health researcher, who conducts research at the interface of child and adolescent health, injury, engineering and behavioral science. Winston’s work is published in peer-reviewed journals and conference proceedings and focuses on the area of traffic injury. Her research to action to impact approach, pragmatic rigor, has led to patents and a focus on evidence-based mobile health (mHealth) for better health. She is a professor of pediatrics at the University of Pennsylvania in Philadelphia and serves as the Scientific Director of the Center for Injury Research and Prevention at Children’s Hospital of Philadelphia, Director of the National Science Foundation Industry/University Cooperative Research Center, the Center for Child Injury Prevention Studies (CChIPS), and Director of a National Science Foundation Research Experience for Undergraduates site.

5 Faculty Seminars

Neuroengineering Faculty Seminar Lucas Parra, City College of New York Brains on Video and Video Games. Kathleen Cullen, Johns Hopkins University Neural Representations of Natural Self Motion: Implications for Perception & Action. Tzahi Cohen-Karni, Carnegie Mellon University Multiscale Topological Design of Biological Interfaces to Novel Nanomaterials. Douglas H. Smith, University of Pennsylvania Tension Can be Good for Your Nerves.

Immunoengineering Faculty Seminar Catherine A. Fromen, University of Delaware Engineering Particle-Lung Interactions to Improve Pulmonary Therapeutics. James L. Riley, University of Pennsylvania Engineering T Cells to Facilitate an HIV Cure. Ankur Singh, Cornell University Engineering Ex Vivo Lymphoid Tissues to Model Immunity, Epigenetics, and Malignancies. Kara Spiller, Drexel University Harnessing the Inflammatory Response for Tissue Regeneration.

Pediatric Bioengineering Symposium Flaura Winston, Children’s Hospital of Philadelphia Precision Child and Adolescent Injury Prevention for Road Safety Alan Flake, Children’s Hospital of Philadelphia Development of the EXTEND System – an EXTra-uterine Environment for Neonatal Development. Matt Maltese, Children’s Hospital of Philadelphia (CHOP) Recent Advances in Pediatric Medical Devices

Mechanobiology Faculty Seminar Rob Mauck, University of Pennsylvania Multi-Functional and Mechano-Active Materials to Direct Tissue Repair. Ken Barbee, Drexel University Transport-dependent Signaling Processes in Flow-induced Endothelial Nitric Oxide Production. Rebecca Wells, University of Pennsylvania Using Mechanics to Understand Fibrosis. Liyun Wang, University of Delaware Pericellular Perlecan and Load-Induced Bone Formation.

6 Parallel Research Sessions

THURSDAY, MARCH 29 8:30 – 9:30 AM 1. BIOMATERIALS/BIOMIMETICS Chair: Christopher Rock, CHOP 27 A Hydrogel Platform to Probe the Influence of Engineered Microenvironments on Stem Cell Fate. Sebastian Vega, Michelle Kwon, John Durel, Kwang Hoon Song, Chao Wang, Robert Mauck, Lin Han, Jason Burdick – University of Pennsylvania 86 Osteogenic Potential of MC3T3 E1 Cells on Block Copolymer NanofiberShish Kebabs. Tony Yu, Diego Galindo, Michele Marcolongo, Christopher Li – Drexel University 42 Tailoring Supramolecular Guest–host Hydrogel Properties with Covalent Double Networks. Claudia Loebel, Amal Ayoub, Jonathan H. Galarraga, Olga Kossover, Haneen Simaan–Yameen, Dror Seliktar, Jason A. Burdick – University of Pennsylvania 308 Electrospun Nanofiber Scaffolds for Anterior Cruciate Ligament Reconstruction. David Brennan – Rowan University

2. BIOMEDICAL IMAGING AND IMAGE PROCESSING Chair: Emad Boctor, Johns Hopkins University 50 A Computational Framework to Optimize Fiducial Marker Layout for Tracking Tumor Deformation. Ye Han, Yoed Rabin, Levent Burak Kara – Carnegie Mellon University 164 Fully Automated Method for the Enhancement of Ventricles from US Data. Ilker Hacihaliloglu, Mrudula Chakravarthy – Rutgers University 138 Discrimination of Malignant and Normal Kidney Tissue with Short Wave Infrared Dispersive Raman Spectroscopy. Yu Sun, Miki Haifler, Alexander Kutikov, Robert Uzzo, Chetan Patil – Temple University 142 Activatable Superparamagnetic Iron Oxide Agents Detect Reactive Oxygen Species In Vitro. Chukwuazam Nwasike, Eunsoo Yoo, Amber Doiron – Binghamton University

3. IMMUNO– AND NEUROENGINEERING Chair: Katie von Reyn, Drexel University 120 Nanodiamond–based Drug Delivery System for the Modulation of Macrophage Behavior. Amanda Pentecost, Minju Kim, Youngji Ko, Sangmin Jeon, Yury Gogotsi, Kwangmeyung Kim, Kara Spiller – Drexel University 246 Neutrophil–endothelia Interactions in Mice Do Not Always Predict their Interactions in Humans. Fariborz Soroush, Yuan Tang, Shuang Sun, Qingliang Yang, Laurie Kilpatrick, Mohammad Kiani – Temple University 207 Reprogramming Monocyte–Derived Macrophages to Promote and Maintain Anti–Inflammatory Behaviors as a Strategy to Treat Traumatic Brain Injury. Kathryn Wofford, Kara Spiller, Kacy Cullen – Drexel University 282 Harnessing Neurovascular Interaction to Guide Axon Growth. Paul Partyka, Ying Jin, Itzhak Fischer, Peter Galie – Rowan University

7 Parallel Research Sessions

2:30 – 3:30 PM 4. TISSUE ENGINEERING/FUNCTIONAL BIOMATERIALS Chair: Peter Lelkes, Temple University 257 Analysis of Thermomechanical Stress Developed During Polarized–light Scanning Cryomacroscopy Experiments, with Applications to Cryopreservation. Prem Solanki, Yoed Rabin – Carnegie Mellon University 57 DREADDs as a Novel Tool for Controlling Calcium Activation in Chondrocytes. Ryan McDonough, Christopher Price – University of Delaware 79 3D–Printing Heterogeneous Porous Patterns in Tissue Engineered Bone Scaffolds. Aine O’Sullivan, Ethan Nyberg, Warren Grayson – Johns Hopkins University 126 Functional Integration of a Tissue Engineered Intervertebral Disc and Translation to a Large Animal Model. Sarah Gullbrand, Beth Ashinsky, Edward Bonnevie, Dong Hwa Kim, Lachlan Smith, Thomas Schaer, Dawn Elliott, Harvey Smith, Robert Mauck – University of Pennsylvania

5. COMPUTATIONAL BIOENGINEERING Chair: Andres Kriete, Drexel University 58 Automated Identification of the Seizure Onset Zone in Drug–Resistant Epilepsy Based on High Frequency iEEG Activity. Stefan Sumsky, Sabato Santaniello – University of Connecticut 263 Heterogeneous Multiscale Framework for Cancer Systems Models and Clinical Applications. Alokendra Ghosh, Ravi Radhakrishnan – University of Pennsylvania 221 An Auto–catalytic Cell Intercalation Mechanism to Understand Tissue Elongation During Morphogenesis. Samira Anbari, Javier Buceta – Lehigh University 31 Analysis of Metabolites from Blood Samples of Pregnant Mothers and Probability of Autism Diagnosis of the Child. Kathryn Hollowood, Stephan Melnyk, Oleksandra Pavliv, Erica Sides, Uew Kruger, Jill S. James, Jürgen Hahn – Rensselear Polytechnic Institute

6. PEDIATRIC BIOENGINEERING Chair: Anita Singh, Widener University 214 Dual–Headed Collapsible Blood Pumps for Dysfunctional Fontan Physiology. Steven Chopski, Marina Lilieholm, Krianthan Govender, Amy Throckmorton – Drexel University 203 Effect of Bracing on Pediatric and Adult Kinematics During Low Acceleration Time Extended Pre–Crash Evasive Swerving. Christine Holt, Thomas Seacrist, Valentina Graci, Ethan Douglass, Sriram Balasubramanian, Kristy Arbogast – Drexel University 358 Thoracic Vertebral Geometry Measurements of Experimental Progressive Scoliosis Induced in the Rabbit by Rib Unilateral Tethering. Ausilah Alfraihat, James Peters, John Casey Olson, Brian Snyder, Robert Campbell, Sriram Balasubramanian – Drexel University 184 Drexel Dragon Heart for Children with Heart Failure. Carson Fox, Harut Sarkisyan, Randy Stevens, Francisco Arabia, Joseph Rossano, Amy Throckmorton – Drexel University

8 Parallel Research Sessions

FRIDAY, MARCH 30, 8:30 – 9:30 AM 7. BIOMECHANICS Chair: Daniel Cortes, Penn State University 93 Nanostructure and Biomechanics of Fibrocartilage Pericellular Matrix: Roles of Collagen V. Chao Wang, Qing Li, Su–Jin Heo, Sheila Adams, Mei Sun, Motomi Iwamoto, Robert Mauck, David Birk, Lin Han – Drexel University 133 Broad Spectrum Analysis of Ultraviolet Lights’ Effect on the Functional and Mechanical Properties of Human Stratum Corneum. Zachary Lipsky, Guy German – Binghamton University 162 Mechanical Injury Alters Tribological Rehydration and Lubrication in Bovine Osteochondral Explants. Margot Farnham, Riley Larson, Christopher Price – University of Delaware 285 Pericellular Matrix is Highly Sensitive to Cartilage Degeneration in Early Post–Traumatic Osteoarthritis. Daphney Chery, Qing Li, Biao Han, Ling Qin, X. Lucas Lu, Motomi Enomoto–Iwamoto, Lin Han – Drexel University

8. BIOMEDICAL SENSORS Chair: Wan Shih, Drexel University 59 An Automated, Triggerable, Continuous–flow, Micro–Electroporation Platform for Performing Single–Cell Level pDNA Transfection. Joseph Sherba, Hao Lin, Jerry Shan, David Shreiber, Jeffrey Zahn – Rutgers University 150 Slowed Down Double–stranded DNA Transport Through Solid–State Nanopores by Using a LiCl Concentration Gradient. Julian Bello, Maksudul Mowla, Nicholas Troise, Jiwook Shim – Rowan University 222 Detecting Cytosine Methylation with LiCl Salt Gradient using the Alpha–hemolysin Biological Nanopore. Trang Vu, Julia Borgesi, Joanna Soyring, Melissa D’Alia, Jiwook Shim – Rowan University 77 Ultra–Sensitive (< 0.001 pg/mL), Multiplexed Detection of Cytokines using Digital Droplet ELISA with High Throughput, Portable Cell Phone Based Readout. Venkata Yelleswarapu, Jonathan Baron, Eshwar Inapuri, David Issadore – University of Pennsylvania

9. DRUG DELIVERY Chair: Margaret Wheatley, Drexel University 175 Lipid Nanoparticle–based mRNA Delivery to the Brain. Venkatesh Deshpande, Mariagemiliana Dessì, Jay Sy – Rutgers University 211 Effectiveness of Targeted Delivery of IGF–1 and MSCs in the Treatment of MI to Determine Cell Survivability. Alexander Delis – Widener University 234 Novel Therapeutic Hydrogel Contact Lenses For Glaucoma: Analysis of Polymeric Structural Kinetics. Amanda Burke, Nicholas Pisani, Liana Wuchte, Mark Byrne – Rowan University 323 Using Multiscale Modeling to Study the Transport of Flexible Polymeric Nanoparticles in Blood Vasculature. Zahera Jabeen, David Eckmann, Portonovo Ayyaswamy, Ravi Radhakrishnan – University of Pennsylvania

9 Parallel Research Sessions

9:45 – 10:45 AM 10. MECHANOBIOLOGY Chair: Adrian Shieh, Drexel University 24 Understanding the Three–dimensional Packing of Curved Epithelia. Luis M. Escudero, Javier Buceta – Lehigh University 141 Indispensible Roles of Decorin in Cartilage ECM Assembly and Poroelastic Mechanical Properties. Biao Han, Qing Li, Mei Sun, Hadi Nia, Ramin Oftadeh, Ling Qin, Renato Iozzo, David Birk, Lin Han – Drexel University 254 Prestrain Regulates Mechanosensation in Fibrous Microenvironments. Edward Bonnevie, Sarah Gullbrand, Tonia Tsinman, Dawn Elliott, Robert Mauck – University of Pennsylvania 121 Absence of Decorin Exacerbates DMM–induced Post–traumatic Osteoarthritis in Mice. Qing Li, Chao Wang, Liu Ouyang, Wei Tong, Wei–Ju Tseng, X. Sherry Liu, Renato V. Iozzo, Ling Qin, David E. Birk, Lin Han – Drexel University

11. BIOMEDICAL DEVICES Chair: Marek Swoboda, Drexel University 21 Biodegradable Piezoelectric Force Sensor. Eli Curry, Thanh Nguyen – University of Connecticut 60 New Nitinol Endovascular Devices. Youngjae Chun – University of Pittsburgh 100 Alzheimer’s Diagnosis for Mild Cognitive Impairment Individuals using Serial Reaction Time Trials. Rei Vardi, Reed Lorimer – Boston University 144 Development of the 2nd Generation Mobile Phone Based Transcutaneous Bilirubinometer. Brandon Harrison, Alexander Dumont, David Gansen, Hendrik Weitkamp, Amy Nwaba, Zack McCormick, Chetan Patil – Temple University

12. ORTHOPEDIC AND REHABILITATION ENGINEERING Chair: Sarah Gullbrand, University of Pennsylvania 85 Multiscale Structure–Function Analysis of Intervertebral Disc Degeneration. Beth Ashinsky, Harvey Smith, Chao Wang, Robert Mauck, Lin Han, Sarah Gullbrand – Drexel University 302 Fabrication of Antibacterial Tri–Magnesium Phosphate Hydrate Coatings on Polyetheretherketone (PEEK) Based Orthopedic Implants with Effective Treatment of Surgical Site Infections. Prabaha Sikder, Sarit Bhaduri – The University of Toledo 99 Diffusion of Biomimetic Proteoglycans Results in Pericellular Augmentation in Articular Cartilage. Evan Phillips, Brett Haislup, Joseph Sincavage, Katsiaryna Prudnikova, Mary Mulcahey, Michele Marcolongo – Drexel University 305 Compliant Assistive Soft Robotic Glove Powered by Super–Coiled Polymer Actuators. Robson Adem – Lafayette College

10 Research Poster Presentations As of March 15th, 2018

BIOMATERIALS The Control Release of Bioactive Proteins to PC12 Paul Gehret, Richard Hoff, Liam Kelly, Temple 309 Cells Won Suh University Carnegie Thermal Conductivity of Cryoprotective Agents in Lili E. Ehrlich, Zhe Gao, John C. Bischof, 71 Mellon the Presence and Absence of Nanoparticles Yoed Rabin University Sol-Gel Method For Coating An Alumina Substrate Rutgers 74 Shyam Kalaria With a Crystalline Film of Yttria University An Expanding, Enzyme Responsive Shape- Justine Paul, Shelby Buffington, Patrick Syracuse 345 Memory Polymer Mather, James Henderson University Vertical Nanowires Enhanced X-ray Radiation Northeastern 231 Qingxuan Li, Liyuan Zheng, Ming Su Damage of Cells University Evaluation of a Novel Injectable K-bioactive Glass Bushra Almishari, Kapil Raghuraman, University of 165 Cement for Osteoporotic Hip Applications Aisling Coughlan Toledo Enhanced Biological Cooling with Encapsulated Northeastern 178 Weike Hu, Ming Su Phase Change Nanoparticles University Adriano Conte, Damon Boorstein, Improving the Macromolecular Alignment and Harrison Hones, Alexander Wildgoose, Rowan 315 Electrical Output of Electrospun PVDF-HFP Shirvani Khosro, Raghid Najjar, Xiao Hu, University Nanofibers through Post-Drawing Wei Xue, Vince Beachley James FitzPatrick, Richard Reynolds, Post-Process Annealing of 3D-Printed Spinal Drexel 264 Karen Wells, Cemile Basgül, Tony Yu, Fusion Cages University Michele Marcolongo Dynamic Light Scattering of Bottlebrush Alicia Kriete, Katsiaryna Prudnikova, Drexel 372 Molecules Michele Marcolongo University Solving the Problem of Post-Operative Infection: University of 289 a Novel Zn-bioactive Blass to Prevent 99.99% of Kapil Raghuraman, Aisling Coughlan Toledo Infections in Vitro Differentiation of Human Neural Stem Cells Temple 306 Weili Ma, Neil Chada, Won Suh Utilizing Peptide-Functionalized Retinoic Acid University 3D Printing of Biomimetic Scaffold for Annulus Rowan 310 Thomas Christiani, Andrea Vernengo Fibrosus Regeneration University Shelby Buffington, Mark Macios, Chau Syracuse 335 Enzymatically Triggered Shape Memory Polymers Lee, Patrick Mather, James Henderson University A Recombinant Vaccine System for Anthrax Cuiyan Lin, Weichiao Huang, Stephen SUNY at 356 Protective Antigen Leppla, Jonathan Lovell Buffalo A Potent OspA-based Vaccine Adjuvanted with a Jasmin Fe Federizon, Wei-Chiao Huang, University at 360 Functionalized Nanoliposome Jonathan F. Lovell Buffalo Synthesis and Surface Modification of Drexel 365 Jing Chen Organometallic-Halide Perovskite Particles University Biocompatibility and Live-Cell Imaging Study of Temple 367 Lindsey Yam, Weili Ma, Won Suh Synthetic Polyethylene Glycol (PEG) Hydrogels University

11 Research Poster Presentations

BIOMECHANICS/MECHANOBIOLOGY Prolonged Water Exposure Promotes Mechanical Niranjana Dhandapani, Maria Skold, Guy Binghamton 143 and Structural Degradation of Human Skin Tissue German University Prashant Chandrasekaran, Qing Li, Chao Roles of Collagen V in Structure and Mechanics of Drexel 94 Wang, Mei Sun, Louis J. Soslowsky, David TMJ condyle cartilage University E. Birk, Lin Han Zakary Beach, Kelsey Robinson, Mihir Dekhne, Ashley Rodriguez, Snehal Induced Deletion of Biglycan in Mature Tendon University of 102 Shetye, Stephanie Weiss, Thomas Adams, Reveals a Surprising Role During Adulthood Pennsylvania Sheila Adams, Mei Sun, David Birk, Louis Soslowsky Computational Model of Lower Extremity Bone Rutgers 104 Brandon Jones, Noshir Langrana Stresses University Jalaj Maheshwari, Nhat Duong, Aditya University of 253 Pediatric ATDs in Simulated Frontal Crashes Belwadi Pennsylvania The Children's Injury Implications in Children from Simulated Shreyas Sarfare, Jalaj Maheshwari, Aditya 255 Hospital of Autonomous Aerial Vehicle Impacts Belwadi Philadelphia Quantifying Solute Diffusivity in Human Alison Wright, Brian Graham, Christopher University of 296 Osteoarthritic Cartilage via Correlation Price Delaware Spectroscopy An Integral Model of Cell Membranes and University of 304 Sreeja Kutti Kandy Cytoskeleton Assembly Pennsylvania Worcester Vimentin Affects Force Transmission Mechanism 316 Minh-Tri Ho-Thanh Polytechnic in Fibroblasts Institute Application of Disturbed Fluid Flow in a Cerebral Nesrine Bouhrira, Brandon DeOre, Peter Rowan 326 Bifurcation Model Galie University Rensselaer 361 Tumor Growth in Vessel-Like Mimics Jonathan Kulwatno, Kristen Mills Polytechnic Institute

12 Research Poster Presentations

BIOMEDICAL IMAGING AND BIOMEDICAL SENSORS Parietal-thalamic Dysconnectivity During New Jersey 52 Sustained Attention Processing in Young Adults Ziyan Wu, Xiaobo Li Institute of with Traumatic Brain Injury Technology Structural Brain Abnormalities in Young Adults New Jersey 53 Remitted and Persistent with Childhood-onset Yuyang Luo, Xiaobo Li Institute of Attention-Deficit/Hyperactivity Disorder Technology Surface Charge Controlled Nucleoli Selective Northeastern 159 Qingxuan Li, Ming Su Staining with Nanoscale Carbon Dots University Alignment and Calibration of a Two-Photon Mitchell Harling, William Breeding, Karissa University of 364 System with SHG Capabilities Tilbury Maine Fracture Guidance in Homogeneous and Binghamton Christopher Maiorana, Mitchell Erbe, 145 Compliant Membranes through Topographical University Travis Blank, Guy German Embedding SUNY Vivinya Gunasekaran, Olivia Ngo, Evan Niemann, Prabagar Sankar, Miriam Wearable Ultrasound Patch for Wearable Putterman, Alec Lafontant, Rose Ann Drexel 170 Ultrasound Patch for Therapeutic Applications DiMaria Ghalili, Michael Neidraeur, University David Margolis, Leonid Zubkov, Michael Weingarten, Peter Lewin Utilizing Secured Online Database to Connect Joochan Kim, Ian Peitzsch, Sakib Hoque, Physicians and Patients with Real-Time Fitness Stony Brook 328 Chanpreet Singh, Liyun Li, Steven Tracker Linked Phone-App for Customized University Crimarco, M. Ete Chan Obesity Treatment (Even Outside of Clinics) Cardiopulmonary Monitoring of Firefighters via University of 324 Real-Time OLED Mounted Display and Android Seth Gergel, Seth Gergel, Ryan Dolan Rhode Island Application Song Han, Mehmet C. Soylu, Ceyhun Rapid, In Situ, Label-Free Genetic Detection of Kirimili, Wei Wu, Bhaswati Sen, Suresh Drexel 377 Enteropathogens in Stool without Genetic Isolation Joshi, Chris Emery, Giang Au, Xiaomin University or Amplificaiton Niu, Richard Hamilton, Wei-Heng Shih, Wan Shih Johns 339 Detection of Shunt Malfunction Dante Navarro Hopkins University

CANCER TECHNOLOGIES Characterization of the Primary Binding Liam Dow, Matthew Dragovich, Wenpeng Lehigh 75 Interactions in CAR-T Therapy Using Atomic Force Cao, Meaghan Gavey, Myrna Yehia, University Microscopy Xiaohui Zhang Intra-Operative Breast Cancer Tumor Imaging Drexel 248 Alexandra Jednorski, Wan Shih System using NIR-Emitting Quantum Dots University

13 Research Poster Presentations

CARDIOVASCULAR, CELLULAR AND MOLECULAR BIOENGINEERING A Model System for Advanced Glycation End Christopher Rock, Antonio Frasca, The Children's 128 Product-Related Structural Degeneration of Samuel Keeney, Giovanni Ferrari, Robert Hospital of Bioprosthetic Valves Levy Philadelphia Worcester Harry Chartoff, Anna Kjelgaard, Tyler 278 Canine Tracheal Stent Design Polytechnic Marshall, Joseph Switzer Institute Ji Sun Park, Jong-Wan Kim, Syandan Promoting Myogenic Potential of Human Chakraborty, Hong Sun Ahn, Nicholas Columbia 92 Endothelial Progenitor Cells by Transactivation of Hornstein, Peter Sims, Hae-Won Kim, University Endogenous MYOD1 In Vivo Jung Keun Hyun, Kam Leong Design and Optimization of a Cholesterol-Binding Anxhela Sinani, Evan Koufos, Angela Lehigh 103 Peptide Based on the Cholesterol Recognition Brown University Aminoacid Consensus Motif Encapsulation of Mesenchymal Stromal Cells in Sarah Salter, Ileana Marrero-Berríos, Rene Rutgers 106 Alginate for the Treatment of Osteoarthritis Schloss, Martin Yarmush University Donor Dependent Effects on the Survival and Justin Bendigo, Sun Peck, George Dodge, Extracellular Matrix Producing Capacity of University of 113 Robert Mauck, Neil Malhotra, Lachlan Mesenchymal Stem Cells following Hypoxia and Pennsylvania Smith TGF-beta Conditioning Endogenous Neural Stem Cell Activation After Rutgers 158 Jeremy Anderson, Misaal Patel, Li Cai Traumatic Brain Injury University Sarah Deng, Kerry McConnaughay, The Tumor Suppressor Protein RASSF1A Olin College 163 Phuwadet Pasarj, Shairaz Baksh, Joanne modulates transcriptional activation of NF-AT of Engineering Pratt Protein Kinase C-DELTA Tyrosine Phosphorylation Fariborz Soroush, Yuan Tang, Shuang Temple 187 is a Critical Regulator of Neutrophil-Endothelial Sun, Jordan Langston, Laurie Kilpatrick, University Cell Interactions in Inflammation Mohammad Kiani Caveolin1 Regulates ATP-Stimulated Nitric Oxide Tenderano Muzorewa, Donald Buerk, Dov Drexel 279 Production In Endothelial Cells Jaron, Kenneth Barbee University Investigating the Relationship Between Vascular Drexel 286 Endothelial Cell Morphology and Function Through Aparna Bhattacharyya, Kenneth Barbee University the Use of Patterned Substrates Rensselaer Human Schwann Cell Response to Tonic Electrical Alagu Chidambaram, Deanna Bouton- 287 Polytechnic Stimulation Thompson, Sally Temple Institute Plasma Membrane Fluidity Measurements of Bovine Aortic Endothelial Cells using Fluorescence Kelly Zaccheo, Kenneth Barbee, Dov Drexel 293 Anisotropy of Trimethylammonium- Diphenyl- Jaron, Donald Buerk University Hexatriene Worcester Effects of Ras/MAPK and PI3K Pathway on Cell Will Linthicum, Minh-Tri Ho Thanh, 354 Polytechnic Mechanics Michele Vitolo, Qi Wen Institute

14 Research Poster Presentations

COMPUTATIONAL AND SYSTEMS BIOENGINEERING Bio-Electro Stimulation Therapy for the Treatment Christina Fontana, Tommi Tsao, Ayan Boston 124 of Motor and Non-Motor Symptoms in Parkinson’s Waite University Disease - A Pilot Study Development of Accelerated Raman Scattering Temple 140 Alexander Dumont, Chetan Patil and Fluorescent Monte Carlo Model University A Markovian Approach Towards Bacterial Size Lehigh 155 Yanyan Chen, Javier Buceta Control and Homeostasis University

DEVICES AND DIAGNOSTIC SYSTEMS Sai Teja Reddy Gidde, Tololupe Verissimo, Simulation of Tissue Insertion Force of Surgical Temple 108 Nuo Chen, Byoung-Gook Loh, Parsaoran Needles using Neural Network Model University Hutapea Hongbo Du, Brandon Smith, Yih-Choung Lafayette 240 A Non-invasive BCI Controlled Wheelchair Yu, Lisa Gabel College Sandra Pelka, Michael Donzanti, Harini Rutgers, Kantamneni, Shravani Barkund, Rahul Dual Function SWIR Emitting Precision-targeted The State 48 Pemmaraju, Swetha Sathi, Zhenghuan Drug Loaded Nanoprobes for Breast Cancer University of Zhao, Mei Chee Tan, Mark Pierce, New Jersey Prabhas Moghe, Vidya Ganapathy Development of a Microfluidic Model of the Michael Raver, Gretchen Mahler, Brian SUNY 72 Glomerulus and Proximal Tubule Philip, Courtney Sakolish Binghamton A Microfluidic Tissue Chip for Modeling Spatial Matthew Osborn, Yoon-Suk Yi, Mark University of 177 Heterogeneity in Human Organ Fibrosis Mondrinos, Dongeun Huh Pennsylvania Development of a High-throughput Neural Circuit Joseph Fantuzzo, Vincent Mirabella, 181 Rutgers Screening Platform using Human Induced Neurons Ronald Hart, Zhiping Pang, Jeffrey Zahn High Throughput Toxicity Assay on Coordinately Qingxuan Li, Angela Su, Junfei Xia, Ming Northeastern 196 Ordered Single Cells with Individual Identity Su University Capturing Single Stranded DNA Compaction with Rowan 332 Trang Vu, Julia Borgesi, Jiwook Shim Biological Nanopore University Yuan Tang, Fariborz Soroush, Elisabetta Inhibition of Protein Kinase C-delta Mitigates Liverani, Shuang Sun, Jordan Langston, Temple 243 Sepsis-Induced Vascular Damage in Brain Qingliang Yang, Laurie Kilpatrick, University Mohammad Kiani Machine Learning-based Microchip Platform for Jin A Ko, Matthew Hemphill, David University of 337 the Diagnosis of Disease Meaney, David Issadore Pennsylvania Sample Preparation for the Capture and Detection Laura Torres, Rebecca Sze-Tu, Zachary Boston 61 of Trichomonas Vaginalis Say, Justin Rosenbohm, Mario Cabodi University Fabrication of Solid-State Nanopore in LiCl using Rowan 191 Julian Bello, Jiwook Shim Controlled Dielectric Breakdown University

15 Research Poster Presentations

DRUG DELIVERY Rutgers, Development of Tissue Mimic Models to Study Keana R. Mirmajlesi, Christopher J. Lowe, The State 44 Free Radical-Initiated Polymer Immobilization David I. Shreiber University of New Jersey 3D Modeling and Simulation of Airflow and Abdurrahman Addokhi, Abdullah Albedah, Boston 73 Aerosol Deposition of Idealized Human Oral Omar Altwijri University Airways A Biomimetic Microfluidic Platform for Anti-tumor Lehigh 112 Lara Reid, Wentao Shi, Yaling Liu Drug Evaluation University Pore Formation and pH Dependent Behavior of Olin College 212 Sarah Deng, Darryl Sasaki Lipid Bilayer Coatings of Engineering The Uptake Study of a Novel Cell Penetrating Temple 269 Neil Chada, Weili Ma, Won Suh Peptide on Multiple Mammalian Cell Types University Synthesis of Chitosan/poly Glutamic Acid Chendong Han, Amber Doiron, Komal SUNY 311 Nanoparticles with Various Characteristics Abhang Binghamton Acetazolamide as Candidate Drug for Reducing Mariagemiliana Dessi, Sonia Yevick, Rutgers 313 Drug Clearance from the Brain via Cerebrospinal Swetha Kodamasimham, Caroline Wood, University Fluid Pathways Jay Sy Targeted Drug Delivery of Gemcitabine Loaded David Brown, John Eisenbrey, Lauren Drexel 341 Polymer Microbubbles for the Treatment of Jablonowski, Flemming Forsberg, University Pancreatic Cancer Margaret Wheatley Development of an Ultrasound-Sensitive Platform Drexel 350 for Co-Delivery of Oxygen and Lonidamine to Nicholas Daroshefski University Hypoxic Tumor Sites Wavelength-selective Cargo Release from Upendra Chitgupi, Shuai Shao, Kevin 351 Porphyrin- and Purpurin-phospholipid Liposome SUNY Buffalo Carter, Wei-Chiao Huang, Jonathan Lovell Mixture Local Delivery of Minocycline and BDNF Zhicheng Wang, Biswarup Ghosh, Jia using Hydrogels Loaded with Self-assembled Nong, Mark Urban, Victoria Trovillion, Drexel 352 Complexes Protects and Enhances Diaphragmatic Megan Wright, Angelo Lepore, Yinghui University Respiratory Function after Spinal Cord Injury Zhong In-Situ Forming PLGA-PEG-PLGA Hydrogel for the Laura Osorno, Robert Getts, Mindy Rowan 318 Delivery of Nucleic Acid Conjugates Nanospheres George-Weinstein, Mark Byrne University for Secondary Cataract Treatment

EDUCATION IN BIOMEDICAL ENGINEERING Enhancing Biomedical Engineering Education Widener 233 Through Continued Adaptive and Experiential Anita Singh, Dawn Ferry, Susan Mills University Learning Environment Abdullah Mohamed Rizvi, Ryan Tam, The Impact In Teaching/Learning With 3D Modeled Stony Brook 329 Amna Haider, Bruce Coluccio, Timucin Laboratory Tools And Video Game Component University Altan, Chanpreet Singh, M. Ete Chan

16 Research Poster Presentations

IMMUNO- AND NEUROENGINEERING Michelle DiFrancesco, Stephen Finocchiaro, Michael Visconti, Jabari Discovery of Small-molecule Inhibitors of PD-1/ Widener 209 Mani, Sachin Patil, Sean Tevis, Griffin PD-L1 Interaction for Cancer Immunotherapy University Walawender, Abhay Aradhya, Jeremy Hofer, Suk-Chung Yoon Effects of Macrophage Phenotype on Biomaterial Pamela Graney, Shahar Ben-Shaul, Drexel 359 Vascularization Shulamit Levenberg, Kara Spiller University Xin Liu, Sunshine Littlecreek, Hilton M. A Novel Multilayer Intracortical Microelectrode Rutgers 78 Kaplan, Joachim Kohn, David I. Shreiber, Probe for High Density and Chronic Recording University Jeffrey D. Zahn Forced Expression of Nkx6.1 Induces Misaal Patel, Jeremy Anderson, Shunyao Rutgers 105 Neurogenesis after Spinal Cord Injury Lei, Rebecca Risman, Li Cai University A Novel Approach to Assessing Johnathan Morris, Conor Kelly, Elizabeth Rowan 153 Neurodevelopmental Toxicity Bealer, Morgan Dean, Mary Staehle University Lafayette 200 SVM Based EEG Detection of True/False Assertion Hongbo Du, Shuyu Jia, Ismail Jouny College Biomechanical Threshold of Neonatal Brachial Widener 237 Anita Singh, Shadi Malaeb, Rachel Magee Plexus after Stretch Injury University Conditioned Gaze Modulation by Deep Brain Maximilian Lowndes, Eunjeong Lee, Brown 268 Stimulation of the Subthalamic Nucleus Kelsea Parker, Wael Asaad University

OTHER Jerry So, Shreyas Chandragiri, Brandon Temple 217 Optical Phantoms for Mobile Diagnosis Harrison, Alexander Dumont, Chetan Patil University Carnegie Thermal Analysis of Marginal Thermal Conditions 241 Purva Joshi, Yoed Rabin Mellon Associated with Cryopreservation by Vitrification University

17 Research Poster Presentations

PEDIATRIC AND REHABILITATION ENGINEERING Computational Modeling of a Modified Blalock- Ellen Garven, Steven Chopski, Randy Drexel 172 Taussig Shunt under Varying Geometric and Stevens, Amy Throckmorton University Physiological Conditions Unique Integrated Switchable Ventricular Assist Harut Sarkisyan, Randy Stevens, Amy Drexel 213 Device for Children and Young Adults Throckmorton University Fluid-Structure Interactions Dominate in a Pitch- Matthew Hirschhorn, Randy Stevens, Amy Drexel 223 adjusting Collapsible Pediatric Blood Pump Throckmorton University Modeling Region-Specific Growth of the Pediatric Param Shah, James Peters, Sriram Drexel 205 Lumbar Spine through Finite Element Methods Balasubramanian University Multivariate Thoracic Deformity Model for Jennifer Sanville, Oscar H. Mayer, Robert Drexel 262 Predicting Pulmonary Function in Early Onset M. Campbell, Jr., Shiker Nair, Shuait Nair, University Scoliosis Ananya Ganesh, Sriram Balasubramanian Age- and Sex- Related Changes in Trunk Range of Jeffrey Hoffman, Ross Chafetz, Sriram Drexel 259 Motion in Pediatric Subjects Balasubramanian University Stevens Cognitive Agency During Visually-altered Raviraj Nataraj, Sean Sanford, Aniket 347 Institute of Operation of a Virtual Hand Prosthesis Shah Technology

TISSUE ENGINEERING/3D PRINTING Xuanyue Li, Calin T. Nicolescu, Miles W. Response of Engineered Fat to Perfusion with Boston 49 Massidda, Jingyi Xia, Tyler J. Ryan, Joe Lipoactive Hormones University Tien Nicole Malofsky, Hafiz Busari, Peter Solvent-cast 3D Printing Biodegradable Polymer- Lehigh 81 Schwarzenberg, Paula Camacho, Hannah based Scaffolds for Tissue Engineering University Dailey, Lesley Chow Charles Rabolli, Ileana Marrero-Berríos, A Novel Cell Culture Device to Study the Cross- Rutgers 176 Anil Shrirao, Rene Schloss, Martin Talk between Cells in an Osteoarthrosis Model University Yarmush Brendan Stoeckl, Hannah Zlotnick, Mike The Porcine Accessory Carpal as a Hast, Mac Sennett, Minwook Kim, Mike University of 294 Model for Biologic Joint Replacement for Eby, Tom Schaer, Robert Mauck, David Pennsylvania Trapeziometacarpal Osteoarthritis Steinberg In Vitro 3D Cancer Modelling in an Adjustable NYU Tandon Nikita Grigoryev, Matija Snuderl, Kalle 343 Nanofiber-Hydrogel Hybrid Synthetic Scaffold for School of Levon Tracking of Glioblastoma Growth and Invasion Engineering

18 Design Poster Presentations As of March 15th, 2018

BIOMATERIALS Naseem Sardashti, Sana Suhail, Ryan Engineered Semi-Synthetic Hybrid Skin Models for University of 18 Cordier, Skylar Buswell, Sangamesh Skin-care and Pharmaceutical Product Evaluation Connecticut Kumbar Effects of Increased Silver Concentration on the Shailaa Kummar, Lawrence Sanders, University of 239 Solubility of PAA/PVP Based Bioactive Glass Aisling Coughlan Toledo Cement Alan Jankowski, Aislinn Keane, Theresa Kosmides, Kevin Lam, Maia Patrie, Milton Design of a Bone Morphogenetic Protein (BMP)- Boston 272 Cornwall-Brady, Jaclyn Grode, Cheryl based Device for Repair of Turtle Carapace University Lee, Charles Innis, Howard Seeherman, Christopher Wilson Polyelectrolyte Complex (PEC) Attachment Testing Avi Desai, Peidong He, Hima Tallam, Rene Rutgers 151 for the Prevention of Abdominal Adhesions Schloss, Noshir Langrana University Dynamic Supramolecular Hydrogels Based on Lehigh 229 Glycosaminoglycan-Peptide Hybrid Molecules for Reilly Callahan University Tissue Regeneration New Portable Solution Pulling-drawing Device for Rowan 260 Dave Jao, Vincent Beachley Aligned Fiber Placement University

BIOMECHANICS AND MECHANOBIOLOGY Non-invasive In Vivo Quantification of Human Skin Kerianne Coulon, Danielle Laiacona, Binghamton 28 Tension Lines Joshua Cohen, Guy German University Fracture Healing Analysis: Creating a Micro- Worcester Daniel Amirault, Maddison Caron, Julie 63 displacement in Distal Radii to Diagnose Healing Polytechnic McLarnon, Alex Witkin Defects Institute Tee It UP: A Smart Golf Mat with Integrated Jeremy Doody, Scott Barlow, Mel University of 96 Infrared Technology for the Visually Impaired Sweeney Rhode Island 116 Wrist Loading Frame to Test Surgical Procedures Leah Singer, Esther Park, Colleen Cassidy Syracuse Nanoscale Mechano-mediated Drug Resistance in Kristen Bougher, Rachel Howley, Boston 132 Cancer Samantha Marfoglio, Emily Margolis University Drop Foot Assistive Device for Flat Foot Squat in Andrew Wilson, Mary Hayles, Claudia Drexel 374 Low Income Countries Duguay, Komal Mehta University

19 Design Poster Presentations

BIOMEDICAL IMAGING AND IMAGE PROCESSING Monitoring Pain in Individuals Who are Nonverbal Rachel Bellisle, Jessika Decker, John University of 29 using a Video-based Algorithm and Android McLinden, Eugene Chabot, Ying Sun Rhode Island Application Jason Mercier, Rachael Amore, Sawyer University of 34 Video-Based Eye Blink Detection Nichols, Jiang Wu, Ying Sun Rhode Island A Graphical User Interface for Enhancement and Nilay Vora, Amrut Sarangi, Ilker Rutgers 114 Localization of Spine Bone Surfaces Hacihaliloglu University 139 DermaSpot: Mobile App for Skin Cancer Detection Muyang Xu, Haris Qureshi, Christopher Le UCONN An Economical & Ergonomic Hydrocephalus University of 149 Garrett Soler, Kazunori Hoshino Software System Connecticut Worcester 251 Hyperspectral Fluorescence Imaging Yenyu Chen, Xiang Pan, Thomas Blais Polytechn. Inst.

BIOMEDICAL SENSORS AND WEARABLE SYSTEMS Intelligent Pressure Sensing Rock Climbing Shoe Jillian Holden, Emma Orton, Riley Temple, University of 37 for Contact Detection of Lower Limb Prosthetics Jordan Anderson, Ying Sun Rhode Island Megan Moss, Bella Nicholson, Matthew The College 43 Alleviate Menstrual Pain (AMP) Device Paulo, Sam Zanetti of New Jersey EOG and EMG Environmental Control for Patients Greggory D'Ambrosca, Ryan Ivone, Peter University of 90 with Mobility and Communicative Disabilities Cerce, Eugene Chabot Rhode Island Reflectance vs. Transmittance Emily Ensom, Sydney Beck, Aaron 91 Photoplethysmograms on Various Locations for URI Gilmore, Tanya Wang, Eugene Chabot Heart Rate Monitoring Korina Stelzenmueller, Autumn Holzinger, 130 S.W.E.E.T. Dreams Baby Monitoring System TCNJ Nicole Schott Human Factors Engineering and Design Zachary Morgan, Jade Chen, Allison Boston 174 Implications for a Bionic Pancreas Stern, Jamil Hakim University Wearable, Remote Patient Monitor for the General Caitlin Kwan, Eric Li, Wiktoria Bis, Sydney Boston 179 Ward Beckers University Gerard Calderone, Maria Lopez Stevens Designing a Digital Goniometer and Dynamometer 189 Cavestany, Alioune Diane, Jay Patel, John Institute of Glove: "The Helping Hand" Capo, Becky Tucci, Vikki Hazelwood Technology Alexander Bossart, Christopher Cline, Stevens Salivary Lactate Sensor for Detection of Colic in 193 Danielle Di Domenico, Alexandra Paciulli, Institute of Horses Marissa Gray Technology Thermal Management System for Transfemoral Anastasia Georges, James Hartman, Temple 227 Prosthesis Danielle Humbert, Jailene Miranda University Implementing Force Sensing Technology in Non- Timothy O'Connor, Colby Thomas, Jiang University of 242 Inhibiting Insoles Paired with Electromyography Wu Rhode Island Sensors to Study Human Gait Augmentative and Alternative Communication Joshua Harper, Zachary DiMartino, Ying University of 245 (AAC) Solution Utilizing Electromyographic Sensor Sun Rhode Island and Andriod Accessibility Software

20 Design Poster Presentations

BIOMEDICAL SENSORS AND WEARABLE SYSTEMS Daniel Salazar Herrera, Matthew Brass, Balance Board with Intelligent Feedback for Ankle University of 247 ThankGod Ugochukwu, Craig Simpson, Rehabilitation Rhode Island Eugene Chabot Stabilizing Breathing Patterns in Preterm Infants Noam Grunfeld, Dean Zeldich, Yu Zhang, Boston 250 Using Mechanical Vibrations Samer Bou Jawde, Bela Suki University BriAnna Puma, Paige Stroh, Philip Binaco, The College 261 PAM Support Vinit Parekh of New Jersey Doppler Ultrasound for Frequent Carotid Artery Matthew Coates, Mark Welsh, Cyrus Drexel 274 Stenosis Monitoring Ahmadi University Utilizing Secured Online Database to Connect Joochan Kim, Ian Peitzsch, Sakib Hoque, Physicians and Patients with Real-Time Fitness Stony Brook 291 Chanpreet Singh, Liyun Li, Steven Tracker Linked Phone-App for Customized University Crimarco, M. Ete Chan Obesity Treatment Even Outside of Clinics EDS aZZZist: An Innovative Eye-Tracking Assistive Kathleen Wan, Thamara Thayalan, Marisa The College 312 Device for Excessive Daytime Sleepiness Palmeri, Yamini Sasidhar, Xuefeng Wei of New Jersey Stevens Obstructive Apnea Monitor for the Neonatal Alena Davis, Nicole Fosko, Zachary 314 Institute of Intensive Care Unit George, Ruth-Ann Gonzales, Marwa Khalil Technology Wearable Technology to Non-Invasively Detect Shasha Graves, Charmi Patel, Alyssa University of 336 Biosignals related to Fatigue in Construction Tacchi Connecticut Workers Stevens Eva Alvarez, Megan Burns, Brian Van 340 UpFeetTM Project Abstract Institute of Oostendorp, Quinn DiPasquale Technology Sheridan Parker, Katie Solon, Stephen Forefoot versus Rearfoot Loading Validation Using Faulkenberry, Ian Goldie, Sagar University of 157 the Smartboot 2.0 Doshi, Erik Thostenson, Karin Gravere Delaware Silbernagel, Jill Higginson

CANCER TECHNOLOGIES Jaspreet Singh Nagi, Kenneth Skorenko, Effects of Dye- Linked Zinc Oxide Nanoparticles Binghamton 30 William Bernier, Wayne Jones, Amber on Living Cells University Doiron Western Adrian Barber, Jacob Willemain, Anthony 168 A Multiplexed Biosensor for Cancer Therapy New England English University Michael Donzanti, Harini Kantamneni, Sandra Precision-targeted SWIR Nanoprobes: A Pelka, Rahul Pemmaraju, Dan Martin, Carolina Rutgers 171 Calibration Tool for Tumor Heterogeneity Bobadilla, MC Tan, Mark Pierce, Prabhas University Moghe, Vidya Ganapathy

21 Design Poster Presentations

CARDIOVASCULAR, CELLULAR AND MOLECULAR BIOENGINEERING A Dynamic Computational Network Model for the Yien Liu, Donald Buerk, Kenneth Barbee, Drexel 46 Role of Nitric Oxide and the Myogenic Response Dov Jaron University in Microvascular Flow Regulation Stevens Boug-illuminator: Lighted Bougie for Emergency Cari Schoffelman, Zach Wilhelm, Bailey 152 Institute of Intubations Bancroft, Martin Technology Cardiopulmonary Monitoring of Firefighters via University of 325 Real-Time OLED Mounted Display and Android Ryan Dolan, Seth Gergel Rhode Island Application. Rochester Electrical Bioreactor Design for Undergraduate Emily Kimber, Shena Marshall, Dillon 84 Institute of Student Application Flood, Jonathan Girard, Lucas Belikis Technology Characterization of the Binding Affinity Between Lehigh 88 the Lynx Protein and the Neuronal Nicotinic Wenpeng Cao, Xiaohui Zhang University Acetylcholine Receptors High-throughput Single-molecule Telomere Drexel 355 Jennifer McCaffrey Characterization using CRISPR/Cas9 University

COMPUTATIONAL AND SYSTEMS BIOENGINEERING Software Tool for Predicting Presence of Non- Rita Chen, Maximilian Christ, Jillian Yong, Boston 47 Alcoholic Fatty Liver Disease Theresa Tuthill University Improved Sampling with Distance-dependent Abigail Sasdelli, Andrew Mahler, Sandor Boston 169 Scoring Functions for Protein Docking Vajda, Dmitri Beglov University

DEVICES, MICRO- AND NANO-BIOENGINEERING, DIAGNOSTIC SYSTEMS Development of a Bioreactor and Hydrogel Rutgers 80 Coating to Study and Improve Implant Rashmi Vasthare University Biocompatibility In-Vitro Assisted Self Treatment for Dysregulation of Zachary Silveira, Samantha Provencher, University of 95 Emotions Based on Biofeedback Elaine Joyce Rhode Island Clayton Andrews, Melissa Austin, Talia Daily-Wear Nasal Breathing Aid (Undergraduate Johns 123 Kirschbaum, Pooja Nair, Eric Cao, Design Competition) Hopkins Theodore Lee A Pressure Ulcer Prevention Pad for Wheelchair Nathaniel Fisher, Bar Stern, Dominick Binghamton 161 Use Pirozzi, YouJoong Park, Guy German University Stephanie Sayegh, Sydney Slavik, Stevens IlluminatORTM Automated Surgical Lighting to Thomas Plunkett, Evan Van Tine, 194 Institute of Improve Operating Conditions and Efficiency Ilya Shnaydman, Becky Tucci, Vikki Technology Hazelwood Use of the BactiBeam Device to Propagate Nicole Gambardella, Kassandra Marrero, Stevens UVC Light in an Endotrachael Tube to Eliminate 204 Thomas Fenton, Lilly Razzaghi, Sally Institute of Ventilator-Associated Pneumonia-Causing Shady, Glen Atlas Technology Bacteria An Accessible Model House for Demonstrating an Alexis Welch, Ahmaad Randall, Amy University of 208 Independent Living Environment Harmon, Ying Sun Rhode Island

22 Design Poster Presentations

DEVICES, MICRO- AND NANO-BIOENGINEERING, DIAGNOSTIC SYSTEMS Feasibility Assessment of Miniaturizing a Amanda Burke, Kelsey Defrates, Thomas Rowan 218 Bioartificial Liver System by Simulation of Madan, Theodore Markiewicz University Ammonia Clearance Efficiency Colin Aitken, Salvatore Finocchiaro, Stevens Electrocautery Device for Major Surgeries Without 276 Terence McEllen, Jhustin Scarlett, Institute of Electromagnetic Interference Christopher Sinatra, Glen Atlas Technology Design of a Novel Injection Surgical Instrument Kiet Anh Tran, Anthony Lowman, Erik Rowan 292 to Safely Deliver a Biomaterial to Spinal Discs for Brewer University Minimally Invasive Surgery Ultra-Violet Germicidal Irradiation for the Kyle Riley, Daniel Medeiros, William University of 298 Prevention of Hospital Acquired Infections Kiernan, Jordan Anderson, Ying Sun Rhode Island David Gansen, Obiora Ufondu, Monica Repurposing a 3D Printer for Automated Force- Temple 363 Parameswaran, Jerry So, Nancy Pleshko, Adaptive Spectral Acquisition University Mugdha Padalkar Assistive Communication Technology for Jane Roberts, Jacob Fischer, Kelly Drexel 375 Amyotrophic Lateral Sclerosis McGuigan, Avi Bash University SUNY Fabrication of a Novel Multichambered Lung-on- 41 Jieen Bae, Gretchen Mahler, Peter Huang Binghamton a-Chip Microfluidic Device University Developing Nanoladder Scaffold for Neuronal Boston 154 Connor Yong, Aaron Sorrin, Natalie Dong Outgrowth and Regeneration University A Spectroscopically Assessable Microfluidic- Winston Colburn, Kenneth Hy, James Temple 180 like-Device with Variable Flow for the Testing of Karchner, Daniel Reiners, Nancy Pleshko University Chondrocyte Extracellular Matrix Deposition Jonathan Gerstenhaber, Sogol Baharlou, Portable Electroblowing Device for Generation of Temple 362 Baran Arig, Madison Baltazar, Yah-el Har- Protein-based Wound Dressings University el, Peter Lelkes Microfluidic Tissue Chips for Modeling Spatial Matthew Osborn, Yoon-Suk Yi, Mark University of 271 Heterogeneity in Human Organ Fibrosis Mondrinos, Dongeun Huh Pennsylvania Integrated Pulse Oximeter for Portable Vital Rory Caldas, Derek Santos, Jiang Wu, University of 290 Assessment Ying Sun Rhode Island Tracy Levi, John Martinez, Jacob Stevens Portable Serum Osmolality Monitoring System for 115 Coumans, Victoria Maglaras, David Institute of Hemodialysis Patients Guirguis Technology A Quantitative Platform for the Clinical Matthew Buonanno, Nile Delso, Austin Drexel 135 Assessment of Biomarker Concentration Hoffman, Kieran O'Donnell, Kara Spiller University SoundMedicine: A Portable Smartphone Based Ross Agen, Nick Thomas, Andrue Caruso, Boston 206 Pneumonia Diagnostic Device Andrew Stoycos University Zahra Ahmed, Lilibeth Martinez, Joshua Malaria detection by Force Analysis through Brown 280 Daniel, Lucy Yip, Amber Buhagiar, Ian Exploitation of Erythrocyte Deformability. University Michelow Western Kathryn Jordan, Gage Riccio, Collette 283 Lab on a Chip for Diagnosis of Chagas Disease New England Connor, Michael Rust University

23 Design Poster Presentations

DRUG DELIVERY Gold Nanoparticle-Based Targeted Drug Delivery Stevens Maria Lopez Cavestany, Beilu Zhang, 249 System for Glioblastoma Multiforme Cell Institute of Yuhao Wang, Hongjun Wang Treatment Technology Multi-modality Cancer Treatment with Multi- Northeastern 258 Ming Su, Yacong Wu functional Nanoparticles University Dyego Miranda, Kevin Carter, Dandan State Luo, Shuai Shao, Jumin Geng, Changnin Multifunctional Liposomes for Image-Guided University of 353 Li, Upendra Chitgupi, Steven Turowski, Intratumoral Chemo-Phototherapy New York at Nasi Li, G. Ekin Atilla-Gokcumen, Joseph Buffalo Spernyak, Jonathan Lovell

EDUCATION IN BIOENGINEERING Abdullah Mohamed Rizvi, Ryan Tam, Video Games With 3D Printed Laboratory Tools Stony Brook 320 Amna Haider, Bruce Coluccio, Timucin And Their Impact In Teaching/Learning University Altan, Chanpreet Singh, M. Ete Chan NEURAL ENGINEERING Portable Electromyography Spectrogram for Melissa Santi, James Baez, Jiang Wu, University of 38 Neuromuscular Research Ying Sun Rhode Island Austin Ramos, Juan Malvar, Zachary Wearable Rotating Permanent Magnets Driven by University of 40 Brown, Tanya Wang, Ying Sun, Brian Brushless Motor for Rehabilitating Stroke Patients Rhode Island Silver Stevens Nanofibrous Nerve Conduit Designed to Gan Zhou, Antoine Carlisle, Harry Koo, 182 Institute of Enhancing Cavernous Nerve Regeneration In Vivo Xiaojun Yu Technology Peel Away Electrode Placement Catheter for Deep Owen Leary, Noah Trac, Zakir Tahiry, Brown 256 Brain Stimulation (DBS) Rohan Rastogi, Shane Lee, Wael Asaad University Think-Blast: A Prosocial Brain-Computer Interface Dylan Davis, Gabe Cas, Haneul Kim, Ian Drexel 109 Platform for Locked-In Syndrome Patients Bilofsky, Jaimie Dougherty University

ORTHOPEDIC ENGINEERING Alexander Lo, Matthew Lo, Luke Morales, Low-Cost Prosthetic Knee for Amputees in Brown 56 Claire Sise, Matthew Borges, Franklin Developing Countries University Tarke, Justin Lee Peter Chien, Zack Hogan, Kevin Mejia, Rutgers 107 Gait Simulation for an External Fixation Device Sruthi Suresh, Noshir A. Langrana University Stevens Functionalized Nanofibrous Scaffolds for Bone 186 Gan Zhou, Xiaojun Yu Institute of Tissue Engineering Technology Modelling Mechanical & Biological Properties of Boston 225 Vithika Nag, James Cho Tendon Tear Progression In-Vivo University Complementary Device for Surgeon Feedback Sean McMillan, Erik Brewer, Mary Staehle, Rowan 281 During Percutaneous Stabilization of Bone Marrow Matthew Fiori, Sara Dailey, Joe DiStefano University Lesions Early Detection of Implant Loosening to Prevent Hanna Dietrich, Joseph DiFranceisco, Rowan 297 Total Implant Failure Miguel Isaga, Luke Austin, Erik Brewer University

24 Design Poster Presentations

OTHER Wrist Pulse Simulation Technology Capable of Mackenzie Mitchell, Jake Morris, Ian University of 36 Representing 28 Pulse Patterns of Traditional Kanterman, Ying Sun Rhode Island Chinese Medicine Stevens Michelle Schumacher, Caroline Culp, Mark 67 The Hybrid II Pessary and Applicator Institute of Youssef, Emilee Erickson Technology Eliminating Microbes on Everyday Surfaces Justine Paul, Jahnessa Payne, Emily Syracuse 76 (EMOES) Pujadas, Pun To Yung University Coupling System for Safe Storage and Daniel Haberek, Margaret Franklin, Daniel University of 89 Transportation of IV Poles O'Brien, Jordan Anderson, Ying Sun Rhode Island A Model for Predicting the Light Intensity of Stevens Edward Curtin, Meredith Foor, Lucas 188 a Bioluminescent Capsule Light Source: A Institute of Heldman, John Van Oostendorp Visualization Source for Endoscopic Procedures Technology Development and Clinical Testing of an Application Ashley Plunkett, Robert DePersia, Miguel Rowan 232 for the Improvement of Severe Sepsis Treatment Isaga, Erik Brewer, Mary Staehle University and SEP-1 Compliance Worcester Stimuli Delivery System for Awake Animal Model Jonathan Perry, Josephine Leingang, 265 Polytechnic MR Imaging Regimes Joseph Miceli, Shivam Mehta Institute Uterine Simulator Model for Training in Manual Melissa Cirillo, Zoe Greenhall, Feyone La, Drexel 273 Vacuum Aspiration Jacqueline Park, Michele Marcolongo University Radio Frequency Identification for Tracking in Delaney Santos, Tyler Gagan, Lauren University of 299 Hospital Personnel Porto Rhode Island

PEDIATRIC AND REHABILITATION BIOENGINEERING Krianthan Govender, Jacqueline Muscella, Novel Geometrically Tunable Blood Shunt for Drexel 226 Kaitlyn John, Nathaniel Neavling, Randy Infants with Severe Congenital Heart Disease University Stevens, Kara Spiller, Amy Throckmorton, James Raleigh, Lily Bruenjes, Philip Stevens Design of the DynaSoar Kinesthetic StanderTM to 192 Chapel, Hannah Timm, Megan Manning, Institute of Improve the Health of Children with Cerebral Palsy Becky Tucci, Vikki Hazelwood Technology Stevens Aditya Bhalla, Darby Destefano, Guido 195 Modular Prosthetic Foot for Child Amputees Institute of Porcelli, Mike Salas Technology Alyssa Anderson, Tierney Clark, Ao Li, Northeast Bioengineering Conference - Infant Syracuse 199 Sarah Venn, Sherri McMullen, Karen Sleep Position Monitor University Klingman Pruthvi Kilaru, Elizabeth Snyder, Kiana Lally, Madison Leiman, Jessica Mannetta, Syracuse 201 Otto-mobile: A Pediatric Transitional Wheelchair Eben Philbin, Madeline Brooks, Maria University Catalane Parth Patel, Harsh Patel, Sonali Dadoo, Drexel 215 Neonatal Nasal Cannula Fixation Device Melissa Mathew University Rebecca Dixon, Sydney Downing, Sarah Stevens Novel Harness for Comfortable Treatment of 322 Ferrell, Elizabeth Gonzales, Julianne Sitler, Institute of Pediatric Hip Dysplasia Sally Shady Technology Children's Mixed Methods Research – A Qualitative Solution 331 Pooja Anantha, Aditya Belwadi Hospital of to a Quantitative Problem Philadelphia 25 Design Poster Presentations

PEDIATRIC AND REHABILITATION BIOENGINEERING Kaitlin Olsen, Noor Aamer, Martha Rivas, The Catholic Smart Toys that Assess Grasp Strength in Infants 349 Rachael Stone, Shams Alhakeem, Sahana University of to Aid in the Diagnosis of Fine Motor Delays Kukke America Stevens Prism Lens Inserts for Double Vision Correction in Fariha Choudhury, Matthew Kandl, Parth 70 Institute of Snowboarding Goggles Patel, Courtney Mould Technology Madison Levine, William Kates, Dale The College 131 CAF Prosthesis Device Johnson, Rose LoPiano of New Jersey Jillian Harris, Tyler Thurmond, Jordan The College 137 Treadmill Body Weight Support System Zawodniak, Alex Truong of New Jersey Amulya Veldanda, Saveetha Raghupathi, The College 238 Thermotherapy Exerciser Aakhila Rameeza, Nic Russo, Connie Hall of New Jersey Design of Metacarpophalangeal Thumb Splint for Grace Ruiz Cooper, Alex Metz, Zakary University of 252 Collegiate Baseball Catchers Chiaradia, Seth Martinez, Sarah Rooney Delaware Connor Mastropoll, Spenser Martin, Maria Worcester 266 Dynamic Correction of Postural Kyphosis Perez Luna, Kirsten Herchenroder, Silvio Polytechnic Torres Betancur Institute Katie Wood, Lucia Cavacini, Samantha Western Design of an Adaptive Golf Club for a Stroke 284 Ostrowsky, Elizabeth Moulton, Tracie New England Patient Klekotka, Andrea Kwaczala University Western Metered Liquid Dispenser for Children at Risk for Courtney Tani, Khaled Alotaibi, John 288 New England Aspiratio Leslie, Judy Cezeaux, Patricia Meyers University

TISSUE ENGINEERING/3D PRINTING Engineering a "Fat-on-a-Chip" Device for Miles Massidda, Calin Nicolescu, Ryan Boston 301 Assessing Lipolytic Activity Jamieson University The Effect of Vascularization on Adipose Tissue Jennifer Hammel, Golnaz Anvari, Temple 166 Glucose Metabolism Evangelia Bellas University Creating a 3D In Vitro Model for Breast-Cancer-to- Michael Masino, Michael Pellegrini, Rutgers 173 Bone Metastasis Joseph Freeman University The Effect of Stiffness Modulation of 3D Collagen Nikolas Di Caprio, Evangelia Bellas, Temple 183 Matrices on Adipocyte Metabolic Regulation Golnaz Anvari University Polycaprolactone Nanofibers Coated in Isabelle Moderski, Nicolas Mann, Rowan 202 Crosslinked Gelatin Hydrogel Film Samantha Glanville University Repairing the Intervertebral Disc: An Ex Vivo Rowan 319 Bovine Organ Culture Model Using an Injectable Thomas Christiani, Andrea Vernengo University Composite Seeded with Stem Cell

26 ABSTRACTS ARE AVAILABLE ONLINE AT http://indexsmart.mirasmart.com/NEBEC_2018/

SPONSORS AND EXHIBITORS Notes Notes The global community of biomedical innovators is broad and extremely diverse, yet all of these innovators share a core characteristic: They do not see problems, but instead solutions and opportunities to translate amazing science into lives saved and health improved. To realize these lifesaving solutions, these innovators believe that collaboration leads to progress for everyone. At Drexel’s School of Biomedical Engineering, Science and Health Systems, we feel fortunate to be part of that unique community. We are also proud to have been instrumental in its development. Founded in 1961 as the United States’ first Biomedical Engineering and Science Institute, we have pushed the boundaries of science and technology for half a century. Along the way, we have forged relationships with a network of partners bridging academia, industry and government to harness our combined potential regionally, nationally and internationally and to fulfill our social contract.

Founded on the excellent basic research taking place at Drexel, our teaching, translational research and service activities are focused on achieving clinical and industrial relevance, thus creating the educational experiences that prepare our students for emerging biomedical challenges. We have been recognized as a model of interdisciplinary collaboration within Drexel University, where breaking down the barriers between fields is a strategic priority. Likewise, our primary translational research partner, the Wallace H. Coulter Foundation, has identified our School as a global best practice in moving discoveries from the laboratory to patients.

As its name suggests, the School places particular emphasis on collaboration among scientific disciplines and our students benefit from our alliances with major research centers, hospitals and biotech companies in the Philadelphia region. The School educates undergraduates in an innovative, accredited curriculum and offers MS, PhD and certificate programs in Biomedical Engineering (BME), Biomedical Science (BMS), and Integrated Biomedical Engineering and Business (IBEB). Concentrations are available in Biomaterials and Tissue Engineering, Imaging and Devices, Neuroengineering, Biomechanics and Bioinformatics.

To learn more please visit: drexel.edu/biomed FUTURE CONFERENCES 2019 RUTGERS UNIVERSITY Chair: Joseph Freeman

2020 PENN STATE UNIVERSITY Chair: Keefe Manning

PLAN TO ATTEND!

3141 Chestnut Street, Philadelphia, PA 19104 drexel.edu/biomed