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The Second Affiliated Hospital Zhejiang University School Of Vanhaverbeke et al Cardiogenic Shock After Myocardial Infarction 2. Bonnefoy E, Lapostolle F, Leizorovicz A, Steg G, McFadden EP, Du- 4. Armstrong PW, Gershlick AH, Goldstein P, Wilcox R, Danays T, Lambert bien PY, Cattan S, Boullenger E, Machecourt J, Lacroute JM, Cas- Y, Sulimov V, Rosell Ortiz F, Ostojic M, Welsh RC, Carvalho AC, Nanas J, CORRESPONDENCE sagnes J, Dissait F, Touboul P; Comparison of Angioplasty and Pre- Arntz HR, Halvorsen S, Huber K, Grajek S, Fresco C, Bluhmki E, Regelin A, hospital Thromboysis in Acute Myocardial Infarction study group. Vandenberghe K, Bogaerts K, Van de Werf F; STREAM Investigative Team. Primary angioplasty versus prehospital fibrinolysis in acute myocar- Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction. dial infarction: a randomised study. Lancet. 2002;360:825–829. doi: N Engl J Med. 2013;368:1379–1387. doi: 10.1056/NEJMoa1301092 10.1016/S0140-6736(02)09963-4 5. Pu J, Ding S, Ge H, Han Y, Guo J, Lin R, Su X, Zhang H, Chen L, He B; EAR- 3. Armstrong PW; WEST Steering Committee. A comparison of phar- LY-MYO Investigators. Efficacy and safety of a pharmaco-invasive strategy macologic therapy with/without timely coronary intervention vs. with half-dose alteplase versus primary angioplasty in ST-segment-eleva- primary percutaneous intervention early after ST-elevation myo- tion myocardial infarction: EARLY-MYO Trial (Early Routine Catheteriza- cardial infarction: the WEST (Which Early ST-elevation myocardial tion After Alteplase Fibrinolysis Versus Primary PCI in Acute ST-Segment- infarction Therapy) study. Eur Heart J. 2006;27:1530–1538. doi: Elevation Myocardial Infarction). Circulation. 2017;136:1462–1473. doi: 10.1093/eurheartj/ehl088 10.1161/CIRCULATIONAHA.117.030582 The Second Affiliated Hospital Zhejiang University School of Medicine (also known as Guangji Hospital), Hangzhou, China In 1869, a tiny refuge was opened in Hangzhou, a city southwest of Shanghai, to help Chinese people overcome addiction to opium. Several years later, the refuge was transformed into a comprehensive hospital named Guangji (upper right, inauguration ceremony), providing Western healthcare services and seeking to foster benevolence and save lives. Under the leadership of Dr David Duncan Main (upper left), a British missionary doctor (hospital president from 1881–1926), the facility developed a reputa- tion as arguably the best hospital in the Far East. One-and-a-half centuries later, renamed the Second Affiliated Hospital Zhejiang University School of Medicine (bottom, campuses), Guangji Hospital has evolved into a flagship institution of medical services and research. For example, its Heart Center is now one of the leading cardiovascular research centers in China. Led by Prof Jian’an Wang, the Center focuses on device development and technical innovation. To address procedural challenges in transcatheter aortic valve replacement, such as bicuspid aortic stenosis, its heart team proposed a so-called Hangzhou Solution, a supra-annular structure- based sizing strategy that typically selects smaller-sized, self-expandable valves. This approach has been shown to improve pro- cedural success and decrease the rates of paravalvular leak and the need for permanent pacemaker implantation in patients with bicuspid aortic valves treated with transcatheter aortic valve replacement. Although its name has changed, the “Guangji spirit” of saving lives and spreading benevolence will never be abandoned; on the contrary, it will be perpetuated by future generations of Second Affiliated Hospital Zhejiang University School of Medicine faculty and staff. Jian-an Wang, MD, PhD Cardiology Department The Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou, China Circulation. 2019;139:137–139. DOI: 10.1161/CIRCULATIONAHA.118.036536 January 2, 2019 139.
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