nd EUROPEAN IMMUNOGENETICS AND HISTOCOMPATIBILITY CONFERENCE ART AND SCIENCE: THE EVOLVING PICTURE 32 OF IMMUNOGENETICS
JOINT CONFERENCE EFI-AIBT
25th Annual Meeting of the Italian Society VENICE LIDO, MAY 9-12, 2018 for Immunogenetics and Transplantation Biology (AIBT) www.efi2018.org 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
TABLE OF CONTENTS
Committees ...... 4
Welcome Addresses ...... 7
General Information ...... 8
Exhibition Plan and Listing ...... 14
Floor Plan ...... 14
Program at a glance ...... 20
Associated Meetings ...... 26
25th AIBT Annual Meeting ...... 28
Program ...... 30 Wednesday ...... 30 Thursday ...... 31 Friday ...... 45 Saturday ...... 55
Poster Presentations ...... 58
Speakers - Chairs ...... 94
Authors’ Index ...... 96
3 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Committees
LOCAL ORGANIZING COMMITTEE CONGRESS CHAIRMAN Valeria Miotti (IT) CONGRESS CO-CHAIRMEN Antonio Amoroso (IT) Carlo Carcassi (IT) LOCAL ORGANIZING COMMITTEE Marco Andreani (IT) Andrea Bontadini (IT) Emanuele Cozzi (IT) Maria E. Fasano (IT) Silvia Gregori (IT) Luca Mascaretti (IT) Benedetta Mazzi (IT) Lia Mele (IT) Franco Papola (IT) Antonina Piazza (IT) Francesca Quintieri (IT) Nicoletta Sacchi (IT) Manuela Testi (IT) Luca Vago (IT)
ORGANIZING SECRETARIAT
Planning Congressi srl Via Guelfa 9 40138 Bologna (Italy) Ph. +39 051-300100 Ext. 130 Fax +39 051-309477 [email protected] www.planning.it
4 25th Annual Meeting of the Italian Society for Immunogenetics
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EFI EXECUTIVE COMMITTEE Elissaveta Naumova (BG), President Joannis Mytilineos (DE) President Elect Mats Bengtsson (SE), Secretary Dave L. Roelen (NL), Deputy Secretary Gwendaline Guidicelli (FR), Treasurer Katia Gagne (FR), Deputy Treasurer
EFI COUNCILLORS Pierre-Antoine Gourraud (FR) Teresa Kauke (DE) Neema Mayor (UK) Valeria Miotti (IT) Fatma Oguz (TR) Jean Villard (CH)
SCIENTIFIC COMMITTEE AND REVIEWERS CHAIR Katharina Fleischhauer (DE) MEMBERS Rainer Blasczyk (DE) Silvia Gregori (IT) Sebastiaan Heidt (NL) James Robinson (UK) Ludvig Sollid (NO) James Traherne (UK) John Trowsdale (UK) Luca Vago (IT) Lotte Wieten (NL)
5 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
WELCOME ADDRESSES
Dear Colleagues and Friends, The 32nd European Immunogenetics and Histocompatibility Conference, joint with the 25th AIBT (Italian Society for Immunogenetics and Transplantation Biology) annual meeting, will be held in Venice, Italy from 9th to 12th of May, 2018. “Art and Science: the evolving picture of Immunogenetics” is the motto of EFI2018 that reflects the dynamism of the Immunogenetics World and its ability to get involved in new addictive biomedical fields, like Leonardo’s masterpiece. I am confident that the meeting will be interesting and exciting, enriching you with the most recent updates in Tissue Typing, Immunogenetics and Transplantation Immunology. The conference will take place in the historical buildings of Palazzo del Cinema and Palazzo del Casinò, located in Venice Lido, the quiet, peaceful and green narrow island that stretches between the open sea and the lagoon, just 15 minutes far from St. Mark’s Square. Marvellous Venice, where, everybody knows, there is no traffic jam and you can wander around the labyrinth of narrow cobbled streets and over the countless bridges that criss-cross the canals. You shall not rush and you might lose track of time. Every corner is unique and worth a look for its artistic value or romantic atmosphere. You can get about Venice by water buses, water-taxis or “Gondolas”, which allows you to visit canals and the lagoon. Don’t miss the chance to see “Ponte dei Sospiri” (Bridge of Sighs) where the convicts saw the lagoon before their imprisonment, sighing at their final view of beautiful Venice through the window before being taken down to their cells; Canal Grande (Grand Canal); Rialto Bridge, Churches, Art-galleries, Murano (famous for its glass works) and Burano (famous for the lace shops). It is a great honour and pleasure to invite you to such a unique, romantic, slow, fascinating place named Venice. Looking forward to seeing you all Valeria Miotti On behalf of AIBT and Conference Co-Chairs Carlo Carcassi and Antonio Amoroso
7 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) GENERAL INFORMATION CONFERENCE VENUE The Conference will take place in Venice Lido, at Palazzo del Cinema and Palazzo del Casinò. Lungomare Guglielmo Marconi, 1861 30126 Lido di Venezia
The is the main Palazzo del Cinema PALAZZO CINEMA facility and screening theatre of the Venice Film Festival. It was built according to the modernist trends of the 1930s, and inaugurated on 10th August 1937 on the occasion of the fifth edition of the festival. In this building will be held: • Opening Ceremony • Plenary Sessions • Closing Ceremony
The Palazzo del Casinò was designed PALAZZO CASINÒ by the Chief Engineer of the City of Venice Eugenio Miozzi in the Rationalist style, influenced by the Fascist architecture of the 1930s and built in the record time of 8 months in 1938. In this building will be held: • 25th AIBT Annual Meeting • Parallel Sessions • Luncheon Sessions • Scientific Poster Reception
8 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
REGISTRATION AND INFORMATION DESKS The registration desks are located on level 1. OPENING HOURS Wednesday 9 May 2018 08:00 - 20:00 Thursday 10 May 2018 08:00 - 19:00 Friday 11 May 2018 08:00 - 19:00 Saturday 12 May 2018 08:00 - 14:00
ON SITE REGISTRATION FEES Member 560 Euro Non Member 620 Euro Student 395 Euro Technician 395 Euro Accompanying Person 110 Euro Gala Dinner 70 Euro
REGISTRATION INCLUDES: • VAT • Access to the conference sessions (not included for Accompanying Persons) • Opening Ceremony and Welcome Reception • Coffee Breaks • Lunches (not included for Accompanying Persons) • VENEZIA UNICA City Card
COFFEE BREAKS Coffee and refreshments will be served to delegates at several points at the exhibition area.
LUNCH BOX Tickets are required for the lunch box and are provided with the registration package. Additional tickets for guests can be purchased through the Registration desk.
CERTIFICATE OF ATTENDANCE The certificate of attendance will be sent by email after the Conference.
9 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) GENERAL INFORMATION PUBLIC TRANSPORTATION Venice’s official City Pass VENEZIA UNICA is a card that offers three days of public transportation use with the ACTV Company in the city area (the card will be activated for the whole days of May 10, 11 and 12). Warning: The fare includes the transport of only one piece of luggage and its three dimensions must not exceed 150 cm. The card will be delivered at the Congress Registration Desk. This card allows you to catch all vaporetto and buses in the City of Venice and buses in Mestre. The Tronchetto parking area in Venice is not reachable by bus, but only by the people mover. PLEASE NOTE THAT PEOPLE MOVER FARE IS NOT INCLUDED IN THE VENEZIA UNICA CARD. The card also includes the free use of the speedboat from Punta Sabbioni to Venice Lido, but it does NOT include bus transportation in Punta Sabbioni (one way fare 1,50 €). The public transportation from/to Marco Polo Airport is provided by another company, named Alilaguna, and is not included in VENEZIA UNICA card.
CONFERENCE APP Full program and more information regarding the Conference are available at the 32nd EFI conference application for iOS and Android. QR CODE to download the conference app.
WI-FI Free Wi-Fi is provided for all delegates and Exhibitors attending the Conference. Network ConventionCenter password EFI2018!
EFI BOOTH The EFI Booth is situated in the Exhibition Hall on level 3. Membership secretary is available: Thursday 10 May 2018 08:30 - 17:00 Friday 11 May 2018 08:30 - 17:00
10 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
SPEAKER READY ROOM The Speaker Ready room is located on level 1. All speakers should deliver their presentations at least 2 hours prior to their speech. OPENING HOURS Wednesday 9 May 2018 15:00 - 18:30 Thursday 10 May 2018 08:00 - 19:00 Friday 11 May 2018 08:00 - 18:30 Saturday 12 May 2018 08:00 - 13:00
POSTERS The Poster Area is located on level 3. The poster panels will be numbered. Please refer to the final poster number of your submission which has been communicated to you earlier. Posters can be mounted on Thursday May 10th (from 8:00 to 10:30) and should be removed on Saturday, May 12th by 9:00. Any posters remaining on poster boards after this time will be disposed of by the organizers. Posters should be attached to poster boards using double sided tape - supply of the tape will be available at the poster area for all poster presenters. Posters will be presented during the Poster Session in the late afternoon of Thursday, May 10th. The presenting author should be available beside his/her poster in order to discuss the data with the attendants.
AIBT ANNUAL MEETING Please note that the official language of the AIBT Meeting will be Italian. No simultaneous translation will be provided.
AIBT MEETING - CONTINUING MEDICAL EDUCATION (CME) Planning Congressi S.r.l. is a CME Provider - identification code no. 38 - and has assigned to the event no. 3,5 credits for Biologists, Chemists, Physicians and Technicians. Please be aware that for the acquisition of credits it is mandatory to have attended the 90% of the whole duration of the congress and selected at least the 75% of correct answers of the CME questionnaire.
11 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) GENERAL INFORMATION EFI CONGRESS - CPE AND CPD CREDITS For the first time at this Conference, Certificates regarding CME/CPD credits awarded will only be provided to delegates after the meeting, following completion of a short survey. The survey is designed to capture information about the meeting, speakers and venue and will inform future conference organisation. The survey link will be sent to delegates by email immediately following the Conference. We hope delegates understand the usefulness of this meeting evaluation survey and of the provision of EFI Educational Credits and ASHI continuing education credits.
EXHIBITION The Exhibition will be held on level 1 and 3. OPENING HOURS Wednesday 9 May 2018 09:00 - 19:00 Thursday 10 May 2018 08:00 - 19:30 Friday 11 May 2018 08:00 - 19:00
SOCIAL PROGRAM EFI Inspectors Dinner (by invitation only) Tuesday 8 May, 19:00 - “La Favorita” Restaurant, Venice Lido Welcome Reception Wednesday 9 May, 19:30 - Palazzo Cinema Foyer Tulip Run (Sponsored by GenDx) Thursday 10 May, 07:00-08:00 Scientific Poster Reception (Sponsored by One Lambda and Lagitre, srl) Thursday 10 May, 18:00-20:00 - Palazzo del Casinò (3rd floor) Ceppellini Dinner (by invitation only) Thursday 10 May, 20:30 - “Da Celeste” Restaurant - Pellestrina Island Speakers Dinner (by invitation only) Thursday 10 May, 20:30 - “Relais Alberti”, Venice Lido Conference Gala Dinner (additional fee) Friday 11 May, 20:45 - Grand Hotel Excelsior, Venice Lido
12 25th Annual Meeting of the Italian Society for Immunogenetics
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EXHIBITION PLAN AND LISTING FLOOR PLAN 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
1st FLOOR PALAZZO DEL CASINÒ AUDITORIUM ALAZZO DEL CINEMA
P ENTRANCE A T COPE R TERRAZZA B D ROOM CASINÒ A C I 9 8 T T ARI A ARI A 7 CORNER CORNER CLOAKROOM SECRE T SECRE T 6 E 5 2 ROOM READY SPEAKER 3 4 1 ROOM ROOM READY READY SPEAKER SPEAKER A PERLA ROOM BOOTH NUMBER D C
B , Inc. ANY NAME eDx COM P Ca r Histogenetics Immuco r One Lambda A Thermo Fisher Scientific Brand
14 25th Annual Meeting of the Italian Society for Immunogenetics
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2nd FLOOR PALAZZO DEL CASINÒ TOILETTE 16 15 14 13 LIFTS 10 11 12 AMICI ROOM TINELLI ROOM 13. CHIARI ROOM 14. KOSCINA ROOM 15. BUY ROOM 16. RONDI ROOM 10. MANGANO ROOM 11. ROSSI DRAGO ROOM 12. MA R
15 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
3rd FLOOR
PALAZZO DEL CASINÒ POSTER EXHIBITION
ROOM 2 ROOM 1 MOSAICI MOSAICI
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CLOAKROOM
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GROUND FLOOR PALAZZO DEL CINEMA A D G CLOAKROOM BOOTH NUMBER TION AREA REGISTR A COMPANY NAME COMPANY GmbH BAG Health Care B CareDx GenDx E Histogenetics C Inc. Immucor, Omixon F One Lambda A Thermo Fisher Scientific Brand A B C D TRIUM ENTRANCE A AUDITORIUM F E G
17 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
PROGRAM AT A GLANCE 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
TIME TUESDAY, 8th MAY Palazzo Palazzo del Casinò Palazzo del Casinò Palazzo del Casinò Palazzo del Casinò ROOM del Cinema Casinò Room Mosaici 1 Room Mosaici 2 Room Buy Room Foyer 1st floor 3rd floor 3rd floor 2nd floor 08:00-08:30
08:30-09:00 EBTI Assembly 09:00-09:30 Meeting
09:30-10:00
10:00-10:30
10:30-11:00
11:00-11:30 ESHI 11:30-12:00 diploma examination
12:00-12:30
12:30-13:00 Accreditation 13:00-13:30 Inspectors Workshop
13:30-14:00
14:00-14:30
14:30-15:00 IBMDR 15:00-15:30 Meeting
15:30-16:00
16:00-16:30
16:30-17:00
17:00-17:30
17:30-18:00
18:00-:18:30
18:30-19:00
19:00-19:30
19:30-20:00
20 25th Annual Meeting of the Italian Society for Immunogenetics
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TIME WEDNESDAY 9th MAY
Palazzo Palazzo Palazzo Palazzo Palazzo Palazzo Palazzo Palazzo del Casinò del Casinò del Casinò del Casinò del Casinò del Casinò del Casinò ROOM del Cinema Casinò Perla Room Amici Room Mangano Rossi Drago Martinelli Buy Room Foyer Room st nd Room Room Room nd 1st floor 1 floor 2 floor 2nd floor 2nd floor 2nd floor 2 floor 08:00-08:30
08:30-09:00
09:00-09:30
09:30-10:00
10:00-10:30
10:30-11:00
11:00-11:30
11:30-12:00 External 12:00-12:30 Proficiency Standards Executive Committee 12:30-13:00 th Testing 25 AIBT Committee Committee Meeting Accreditation Annual Meeting Committee 13:00-13:30 Meeting Meeting 13:30-14:00
14:00-14:30
14:30-15:00
15:00-15:30 Open Education Meeting of Committee 15:30-16:00 the Population Genetics Working 16:00-16:30 Group
16:30-17:00
17:00-17:30
17:30-18:00
18:00-:18:30 Opening 18:30-19:00 Ceremony
19:00-19:30
19:30-20:00
20:00-20:30 Welcome 20:30-21:00 Reception
21:00-21:30
21 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
TIME THURSDAY, 10th MAY
Palazzo Palazzo Palazzo Palazzo Palazzo Palazzo Palazzo del Casinò del Casinò del Casinò del Casinò del Casinò del Casinò ROOM del Cinema Casinò Room Mosaici 1 Mosaici 2 Perla Room Buy Room Martinelli Auditorium st Room Room st nd Room 1 floor 3rd floor 3rd floor 1 floor 2 floor 2nd floor 08:00-08:30
08:30-09:00 PLENARY SESSION 1 09:00-09:30 Governance of immune- modulation in 09:30-10:00 transplantation 10:00-10:20 Coffee break & Poster viewing
10:20-10:50 Teaching Oral Session 1 Oral Session 2 Session 1 Meet the MHC Evolution New How NGS Scientific 10:50-11:20 Expert 1 - Anthropology Technologies technology is Committee ESHI Diploma - Population and changing the Meeting Genetics Bioinformatics way of HLA 11:20-11.50 typing
11.50-12.00 Pause 12:00-12:30 Luncheon Luncheon Luncheon Session Session Session 12:30-13:00 CareDx GenDx One Lambda Executive Committee 13:00-13:30 Lunch Box and Co-ordinators 13:30-14:00 Luncheon Luncheon Luncheon Meeting Session Session Session 14:00-14:30 Immucor Omixon One Lambda 14:30-14:40 Pause Teaching 14:40-15:10 Session 2 Meet the Oral Session 3 Oral Session 4 Clinical Expert 2 Immunotherapy Haematopoietic impact of 15:10-15:40 EPT External proficiency - Gene Therapy - Stem Cell de-novo HLA testing Cellular Therapy Transplantation antibodies in 15:40-16:10 solid organ transplantation 16:10-16:30 Coffee break & Poster viewing 16:30-17:00 PLENARY 17:00-17:30 SESSION 2 Solid Organ 17:30-:18:00 Transplantation
18:00-18:30
18:30-19:00 Scientific Poster Reception 19:00-19:30
19.30-20.00
22 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
TIME FRIDAY, 11th MAY Palazzo Palazzo Palazzo Palazzo del Casinò del Casinò del Casinò ROOM del Cinema Mosaici 1 Room rd Mosaici 2 Room Perla Room Auditorium rd st 3 floor 3 floor 1 floor 08:00-08:30
08:30-09:00 PLENARY SESSION 3 09:00-09:30 HSCT Current clinical perspectives 09:30-10:00 10:00-10:20 Coffee break & Poster viewing
10:20-10:50 Teaching Session 3 Tools for a successful HSCT: evaluation of HLA allele 10:50-11:20 Oral Session 5 Oral Session 6 frequencies, anti-HLA Solid Organ Transplantation NK and Miscellaneous antibodies, structural and expression models for 11:20-11.50 permissive mismatches 11.50-12.00 Pause
12:00-12:30 Luncheon Session Luncheon Session 12:30-13:00 Bag Healthcare One Lambda 13:00-13:30 Lunch Box
13:30-14:00 Luncheon Session Luncheon Session 14:00-14:30 Histogenetics One Lambda 14:30-14:40 Pause
14:40-15:10 Oral Session 7 Teaching Session 4 Reproduction, How to prepare for an 15:10-15:40 SPECIAL JOINT SESSION inspection: demonstrating WMDA and EFI Autoimmunity, Infection & Cancer how quality standards 15:40-16:10 are met 16:10-16:30 Coffee break & Poster viewing 16:30-17:00 PLENARY SESSION 4 17:00-17:30 Immunogenetics beyond HLA 17:30-:18:00
18:00-18:30 18:30-19:00 EFI General Assembly 19:00-19:30
19.30-20.00
20.00-20.30 20.30-24.00 Conference Gala Dinner
23 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
TIME SATURDAY, 12th MAY Palazzo Palazzo del Casinò Palazzo del Casinò Palazzo del Casinò Palazzo del Casinò ROOM del Cinema Casinò Room Mosaici 1 Room Mosaici 2 Room Perla Room Auditorium 1st floor 3rd floor 3rd floor 1st floor 08:00-08:30
08:30-09:00
09:00-09:30 Best Abstract Session 09:30-10:00
th th 10:00-10:30 17 and 18 IHW reports 10:30-10:50 Coffee Break 10:50-11:20 PLENARY 11:20-11.50 SESSION 5 New Frontiers in 11.50-12.20 Immunogenetics 12:20-12:50 Closing Lecture 12:50-13:30 Closing Ceremony
24 25th Annual Meeting of the Italian Society for Immunogenetics
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ASSOCIATED MEETINGS
25th AIBT ANNUAL MEETING
PROGRAM 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) ASSOCIATED MEETINGS Tuesday 8 May 2018
CASINÒ ROOM - PALAZZO CASINÒ (1st FLOOR) 8:30-9:30 EBTI Assembly Meeting Chairperson: Marco Andreani 11:30-18:30 IBMDR Meeting Chairperson: Nicoletta Sacchi
BUY ROOM - PALAZZO CASINÒ (2nd FLOOR) 09:00-14:00 ESHI diploma examination Chairperson: David Turner FOYER - PALAZZO CINEMA 9:30-16:30 Accreditation Inspectors Workshop Chairperson: Andrea Harmer
Wednesday 9 May 2018 AMICI ROOM - PALAZZO CASINÒ (2nd FLOOR) 8:30-16:00 External Proficiency Testing Committee Chairperson: Falko Heinemann
MANGANO ROOM - PALAZZO CASINÒ (2nd FLOOR) 8:30-16:30 Executive Committee Meeting Chairperson: Elissaveta Naumova
ROSSI DRAGO ROOM - PALAZZO CASINÒ (2nd FLOOR) 8:30-16:00 Standards Committee Meeting Chairperson: Juha Peräsaari
26 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Wednesday 9 May 2018
MARTINELLI ROOM - PALAZZO CASINÒ (2nd FLOOR) 9:00-16:30 Accreditation Committee Meeting Chairperson: Andrea Harmer
BUY ROOM - PALAZZO CASINÒ (2nd FLOOR) 13:30-17:00 Education Committee Chairperson: David Turner
CASINÒ ROOM - PALAZZO CASINÒ (1st FLOOR) 15:00-16:30 Open Meeting of the Population Genetics Working Group Chairperson: Alicia Sanchez-Mazas
Thursday 10 May 2018 BUY ROOM - PALAZZO CASINÒ (2nd FLOOR) 10:00-12:00 Scientific Committee Meeting Chairperson: Katharina Fleischhauer
MARTINELLI ROOM - PALAZZO CASINÒ (2nd FLOOR) 12:15-14:30 Executive Committee and Co-ordinators Meeting Chairperson: Elissaveta Naumova
Friday 11 May 2018 PERLA ROOM - PALAZZO CASINÒ (1st FLOOR) 18.00-19.30 EFI General Assembly
27 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
th 25 AIBT ANNUAL MEETING Accreditato ECM Wednesday 9 May 2018
PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)
9:00 Apertura lavori I SESSIONE Moderatori: Valeria Miotti, Manuela Testi 9:30 Il donatore non familiare, adulto e cord: quali prospettive nell’era del trapianto aploidentico
WEDNESDAY Nicoletta Sacchi 10:00 Anticorpi DSA nel Trapianto di CSE, gestione e desensibilizzazione Giovanni Rombolà 10:30 Metodologia di studio del chimerismo in relazione alle diverse tipologie di trapianto di CSE: ricaduta clinica Marco Andreani 11:00 Nuovi targets della risposta immune umorale nel trapianto d’organo Emanuele Cozzi
11:30 Coffee break
28 25th Annual Meeting of the Italian Society for Immunogenetics
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Wednesday 9 May 2018
PERLA ROOM - PALAZZO CASINÒ (1st FLOOR)
II SESSIONE Moderatori: Lia Mele, Antonina Piazza 11:45 Epigenetica e nuove tecnologie: cosa cambia nell’associazione HLA e malattie immunomediate
Carlo Carcassi WEDNESDAY 12:15 Il Controllo di qualità Esterno Francesca Quintieri
13:30 Lunch
14:45 AIBT nella storia Valerio Misefari 15:15 Conclusione lavori 15:30 Assemblea dei Soci
29 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) PROGRAM Wednesday 9 May 2018
OPENING CEREMONY AUDITORIUM - PALAZZO CINEMA 17:30-18:00 Welcome Addresses Valeria Miotti, Carlo Carcassi, Antonio Amoroso, Elissaveta Naumova, Alessandro Nanni Costa
18:00-18:30 In memory of Jon van Rood Frans H.J. Claas 18:30-18:55 Julia Bodmer Award Katharina Fleischhauer WEDNESDAY 18:55-19:00 HLA Award Steven G.E. Marsh 19:00-19:30 Ceppellini Lecture Elissaveta Naumova 19:30-20:00 Sounds from Italy - Classic and cinema
20:00-21:30 Welcome Reception
30 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Thursday 10 May 2018
PLENARY SESSION 1 AUDITORIUM - PALAZZO CINEMA Governance of immune-modulation in transplantation Chairpersons: Frans H.J. Claas, Silvia Gregori 8:30-9:00 Mesenchimal stem cells in transplantation Katarina K. Le Blanc 9:00-9:30 Exosome Adrian E. Morelli 9:30-10:00 Innate lymphoid cells Hergen Spits
10:00-10:20 Coffee break & Poster viewing PALAZZO CASINÒ THURSDAY
31 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Thursday 10 May 2018
PARALLEL SESSIONS CASINÒ ROOM - PALAZZO CASINÒ (1st FLOOR) 10:20-11:50 Meet the Expert 1 - ESHI Diploma Marco Andreani, David Turner • Overview of the ESHI Diploma David Turner • Preparation for the Application and Examination Marco Andreani • New EFI CME/CPD scheme David Turner • Q&A
MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR) 10:20-11:50 Oral Session 1: MHC Evolution - Anthropology - Population Genetics Chairpersons: Pierre-Antoine Gourraud, Alicia Sanchez-Mazas THURSDAY O9 AGE-DEPENDENT CHANGES IN REGULATION OF HLA-DQ GENE EXPRESSION (WITHDRAWN) Marie Cerna 1, Martin Chmel 1, Michael Hudec 1, Adela Rihova 1, Elena Silhova 2 1Charles University, Third Faculty of Medicine, Prague, Czech Republic - 2University Hospital Kralovske Vinohrady, Prague, Czech Republic O10 THE DISTRIBUTION OF HUMAN LEUKOCYTE ANTIGEN A AND B GENES IN POPULATIONS IS STRONGLY SHAPED BY THEIR FUNCTIONAL RELATIONSHIP Da Di 1, Jose M. Nunes 1, Alicia Sanchez-Mazas 1 1University of Geneva, Geneva, Switzerland O11 HLA ALLELE AND HAPLOTYPE FREQUENCIES CHARACTERIZED USING NEXT-GENERATION SEQUENCING METHODS IN UNRELATED WORLD-WIDE POPULATIONS: SUMMARY FROM THE 17TH INTERNATIONAL HLA AND IMMUNOGENETICS WORKSHOP Lisa E. Creary 1, Chia-Jung Chang 2, Gonzalo Montero-Martin 1, Kalyan C. Mallempati 3, Sridevi Gangavarapu 3, Kazutoyo Osoegawa 3, Tamara Vayntrub 3, Marcelo A. Fernández-Viña 1 1Stanford University School of Medicine, Palo Alto, United States of America - 2Stanford Genome Technology Center, Palo Alto, United States of America - 3Stanford Blood Center, Palo Alto, United States of America
32 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Thursday 10 May 2018
PARALLEL SESSIONS MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR) O12 THE MICRORNA BINDING-SITE REGION OF MHC GENES PLACED IN AN EVOLUTIONARY CONTEXT Corrine M.C. Heijmans 1, Cristy Verzijl 1, Hans J.H.A. Rijnaard 1, Jeffrey Oliveira 1, Kaat Tielens 1, Natasja G. de Groot 1, Ronald E. Bontrop 1 1Biomedical Primate Research Centre, Rijswijk, Netherlands O13 HLA CLASS I HAPLOTYPE DIVERSITY IS CONSISTENT WITH SELECTION FOR FREQUENT EXISTING HAPLOTYPES Yoram Louzoun 1, Loren Gragert 2, Martin Maiers 3, Idan Alter 1, Stephanie Fingerson 3 1Bar Ilan University, Ramat Gan, Israel - 2Tulane University, New Orleans, United States of America - 3National Marrow Donor Program, Minneapolis, MN, United States of America O14 MANY MHC-B ALLELES OF THE BONOBO SHARE SIMILAR FEATURES WITH HLA ALLELES THAT ARE ASSOCIATED WITH PROTECTION FROM MALARIA Natasja G. de Groot 1, Corrine M.C. Heijmans 1, Philippe Helsen 2, Jeroen M.G. Stevens 2, Ronald E. Bontrop 1 1Biomedical Primate Research Centre, Rijswijk, Netherlands - 2Royal Zoological Society of Antwerp, Antwerp, Belgium O15 EVOLUTIONARY FATE OF NEW ALLELES Pedro Cano 1 1Moffitt Cancer Center, Tampa, United States of America
O16 ANCIENT ORIGIN OF TWO CLADES OF DPB1 ALLELES THURSDAY Gerhard Schöfl1 , Steffen Klasberg 1, Kathrin Lang 1, Alexander H. Schmidt 2, Vinzenz Lange 1 1DKMS Life Science Lab, Dresden, Germany - 2DKMS, Tübingen, Germany
33 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Thursday 10 May 2018
PARALLEL SESSIONS MOSAICI 2 ROOM - PALAZZO CASINÒ (3rd FLOOR) 10:20-11:50 Oral Session 2: New Technologies and Bioinformatics Chairpersons: Emanuele Cozzi, Eric Spierings O17 NEXT-GENERATION TARGET CAPTURE AND DIRECT LONG READ SEQUENCING OF THE MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) Johannes Dapprich 1, Oscar A. Pérez-Escobar 2, Sidonie Bellot 2, Jessica Rothe 3, Stefanie Köcher 3, Marion Nagy 3, Mehmet Tevfik Dorak4 , Stephen Rudd 5, Fabian Grunz 6, Nicolas Krezdorn 6, Klaus Hoffmeier 6 1Generation Biotech, Lawrenceville, United States of America - 2Royal Botanic Gardens Kew, Richmond, United Kingdom (Great Britain) - 3Institute for Legal Medicine, Berlin, Germany - 4Kingston University, London, United Kingdom (Great Britain) - 5Oxford Nanopore Technologies, Oxford, United Kingdom (Great Britain) - 6GenXPro, Frankfurt, Germany O18 HIGH RESOLUTION HAPLOTYPE ANALYSES OF CLASSICAL HLA GENES IN FAMILIES FOR THE 17TH INTERNATIONAL HLA AND IMMUNOGENETICS WORKSHOP Kazutoyo Osoegawa 1, Lisa E. Creary 2, Kalyan Mallempati 1, Sridevi Gangavarapu 1, Steven J. Mack 3, Medhat Askar 4, Marcelo Fernandez Vina 2 1Stanford Blood Center, Palo Alto, United States of America - 2Stanford University School of Medicine, Palo Alto, United States of America - 3Children’s Hospital Oakland Research Institute, Oakland, United States of America - 4Baylor University Medical Center, Dallas, United States of America
THURSDAY O19 IPD-MHC DATABASE: IMPROVING TOOLS FOR THE ANALYSIS OF THE MAJOR HISTOCOMPATIBILITY COMPLEX Giuseppe Maccari 1, James Robinson 2, Natasja G. de Groot 3, Nel Otting 3, Ronald E. Brontop 3, John A. Hammond 4, Steven GE. Marsh 2 1The Pirbright Institute and Anthony Nolan, Guildford, United Kingdom (Great Britain) - 2Anthony Nolan and UCL Cancer Institute, London, United Kingdom (Great Britain) - 3Biomedical Primate Research Centre, Rijswijk, Netherlands - 4The Pirbright Institute, Guildford, United Kingdom (Great Britain) O20 IS NANOPORE SEQUENCING READY FOR PRIME TIME? ACCURATE HLA CLASS I GENOTYPING AND DETECTION OF NOVEL SEQUENCE VARIANTS BASED ON FULL GENE SEQUENCE ANALYSIS Vineeth Surendranath 1, Kathrin Lang 1, Alexander H. Schmidt 2, Gerhard Schöfl1 , Vinzenz Lange 1 1DKMS Life Science Lab, Dresden, Germany - 2DKMS, Tübingen, Germany O21 SIMULATING THROMBOCYTE TRANSFUSIONS TO INVESTIGATE THE ROLE OF T-HELPER AND B-CELL EPITOPES ON THE RISK FOR PLATELET REFRACTORINESS Kirsten Geneugelijk 1, Talitha de Hoop 1, Eric Borst 1, Eric Spierings 1 1University Medical Center Utrecht, Utrecht, Netherlands
34 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Thursday 10 May 2018
PARALLEL SESSIONS MOSAICI 2 ROOM - PALAZZO CASINÒ (3rd FLOOR) O22 CONVERGING EVOLUTION LEADS TO NEAR MAXIMAL JUNCTION DIVERSITY THROUGH PARALLEL MECHANISMS IN B AND T CELL RECEPTORS Yoram Louzoun 1, Jennifer Benichou 1 1Bar Ilan University, Ramat Gan, Israel O23 FULL-LENGTH HLA AND KIR ALLELE SEQUENCE CHARACTERIZATION WITH DR2S Steffen Klasberg 1, Kuntal Worah 1, Marie Günther 1, Kathrin Lang 1, Alexander H. Schmidt 2, Vinzenz Lange 1, Gerhard Schöfl1 1DKMS Life Science Lab, Dresden, Germany - 2DKMS, Tübingen, Germany O24 COMPUTATIONAL SIMULATIONS DEMONSTRATE THE FEASIBILITY AND BENEFIT OF EPITOPE MATCHING FOR KIDNEY TRANSPLANTATION Matthias Niemann 1, Nils Lachmann 2, Oliver Staeck 2, Eric Spierings 3 1PIRCHE AG, Berlin, Germany - 2Charité - Universitätsmedizin Berlin, Berlin, Germany - 3UMC Utrecht, Utrecht, Netherlands
PERLA ROOM - PALAZZO CASINÒ (1st FLOOR) 10:20-11:50 Teaching Session 1 How NGS technology is changing the way of HLA typing
Joannis Mytilineos, Sarah Patricia Peacock THURSDAY • The whole gene: Application and implementation of whole gene sequencing in the clinical lab Katy Latham • NGS in a Transplant Center: a French experience Béatrice Bardy • Sequencing with nanopores: current status and near future potential Vineeth Surendranath • General discussion & close
35 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Thursday 10 May 2018
LUNCHEON SESSIONS CASINÒ ROOM - PALAZZO CASINÒ (1st FLOOR) 12:00-13:00 Luncheon Session - CareDx Welcome Roswitha Keller, PhD VP, Transplant Laboratory Solutions, CareDx International, Vienna, Austria Olerup QTYPE development, utilizing the full potential of a primer-probe based assay in HLA typing Ben Passey, Development Manager, CareDx International, Stockholm, Sweden Speed and precision in real time; Results from an Olerup QTYPE Multicentre Clinical Validation Study John Lunz, PhD D(ABHI), Director of the Histocompatibility Laboratory, Gift of Hope Organ & Tissue Donor Network, Itasca IL, USA
13:00-13:30 Lunch
13:30-14:30 Luncheon Session - Immucor Clinical Relevance of Complement Activating Pre-formed Donor Specific Antibodies in Crossmatch Positive HLA-incompatible Renal
THURSDAY Transplantation: a Multicentre Study Dr. Olivia Shaw, Viapath at Guy’s Hospital, Clinical Transplantation Lab at Guy’s Hospital, Clin Transpl Dept., New City Court Post Transplant Monitoring - kSORT Analysis in a Real World Context Dr. Michael Spigarelli, Vice President Medical Affairs - Immucor Inc.
36 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Thursday 10 May 2018
LUNCHEON SESSIONS MOSAICI 2 ROOM - PALAZZO CASINÒ (3rd FLOOR) 12:00-13:00 Luncheon Session - GenDx Improvements in Transplantation Diagnostics Chairperson: Wietse Mulder What is next in NGS HLA typing Daniel Mathow, PhD Senior Sales & Application Manager, GenDx Daily practice of HLA typing in a clinical setting Marte Viken, PhD Senior Scientific Advisor, Oslo University Hospital, Norway Recent improvements in NGSengine to make life easier Erik Rozemuller, PhD Senior Scientist Bioinformatics, GenDx Update in chimerism clinical practice Dominique Bories, MD, PhD Head Moleculair Onco-Hematology Laboratory, Henri Mondor Hospital Creteil, France Chimerism monitoring made easy Maarten Penning, PhD CTO, GenDx Conclusion Wietse Mulder, PhD CEO, GenDx THURSDAY 13:00-13:30 Lunch
13:30-14:30 Luncheon Session - Omixon Holotyping without Borders - Holotype HLA V2. Experiences Within and from Outside the EU for the Benefit of the Wider Transplant Community The Lunchtime Symposium will focus on the experiences of existing Holotype HLA users in- and outside the European Union. Three Guest Speakers, Vera Siffnerova (UHKT), Dr. Elena Shagimardanova (Kazan Federal University) and Derrick Nelson (South African National Blood Service) are going to share their experience with the new Holotype HLA V.2. protocol. Omixon’s CEO, Dr. Peter Meintjes will announce major product innovations and new directions for the company. - Welcome & Introduction - Presentations by Guest Speakers - Announcement of Major Product Enhancements by Dr. Peter Meintjes (CEO, Omixon)
37 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Thursday 10 May 2018
LUNCHEON SESSIONS PERLA ROOM - PALAZZO CASINÒ (1st FLOOR) 12:00-13:00 Luncheon Session - One Lambda Defining 11-HLA loci in a diverse cord blood bank using the AllType™ NGS Assays Sandra Guerra, Ph.D National H&I Service Development Laboratory Post-Doctoral Research Scientist NHS Blood and Transplant London, United Kingdom
13:00-13:30 Lunch
13:30-14:30 Luncheon Session - One Lambda Epitope Matching vs. HLA Matching in Organ Transplantation Chris Wiebe, MD Nephrologist, University of Manitoba Canadian Blood Services Winnepeg, Manitoba Canada THURSDAY
38 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Thursday 10 May 2018
PARALLEL SESSIONS CASINÒ ROOM - PALAZZO CASINÒ (1st FLOOR) 14:40-16:10 Meet the Expert 2 - EPT External proficiency testing Falko Heinemann • Extending the Spectrum of EPT in H&I • EPT in H&I: From History to New Developments • Organization of EPT: Schemes, Workshops and Inter-Laboratory Exchanges • Specialist EPT Schemes: HNA, HPA, mHAg and KIR • The Impact of New Technology on EPT: Next Generation Sequencing and Single Antigen Bead tests - ‘Result based’ or ‘method based’ assessment?
MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR) 14:40-16:10 Oral Session 3:
Immunotherapy - Gene Therapy - Cellular Therapy THURSDAY Chairpersons: Rainer Blasczyk, Mats Bengtsson O25 NKG2A EXPRESSION IS NOT PER SE DETRIMENTAL FOR THE ANTI-MULTIPLE MYELOMA ACTIVITY OF HIGH DOSE IL-2 ACTIVATED NATURAL KILLER CELLS IN AN IN VITRO SYSTEM MIMICKING THE TUMOR MICROENVIRONMENT Niken M. Mahaweni 1, Femke Ehlers 1, Subhashis Sarkar 1, Johanna W. H. Janssen 1, Marcel G. Tilanus 1, Gerard M. J. Bos 1, Lotte Wieten 1 1Maastricht University Medical Center, Maastricht, Netherlands O26 ALLOREACTIVE NATURAL KILLER CELL THERAPY AS NOVEL APPROACH FOR BREAST CANCER Femke Ehlers 1, Michel van Gelder 1, Nicky Beelen 1, Marcel Tilanus 1, Marjolein Smits 1, Loes Kooreman 1, Gerard Bos 1, Lotte Wieten 1 1Maastricht University Medical Center, Maastricht, Netherlands O27 IN VIVO CRISPR/CAS9 SCREENING FOR THE IDENTIFICATION OF NOVEL PLAYERS IN LEUKEMIA IMMUNE ESCAPE Eleonora Draghi 1, Alessandro Migliara 2, Giacomo Oliveira 1, Arnolda Jakovija 1, Nice Turazzi 1, Antonella Antonelli 1, Barbara Camisa 1, Francesco Santaniello 1, Monica Volpin 1, Daniela Cesana 1, Eugenio Montini 1, Bernard Gentner 2, Attilio Bondanza 1, Chiara Bonini 1, Fabio Ciceri 1, Angelo Lombardo 2, Luca Vago 1 1San Raffaele Hospital Scientific Institute, Milan, Italy -2 San Raffaele-Telethon Institute for Gene Therapy, Milan, Italy
39 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Thursday 10 May 2018
PARALLEL SESSIONS MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR) O28 EXPLORING FCγRIIIA GENE VARIATION: NOVEL APPROACHES TO EXAMINE FULL-LENGTH GENE POLYMORPHISMS Timo I. Olieslagers 1, Niken M. Mahaweni 1, Ivan Rivas Olivares 1, Stefan Molenbroeck 1, Gerard M. Bos 1, Mathijs Groeneweg 1, Marcel G.J. Tilanus 1, Christina E.M. Voorter 1, Lotte Wieten 1 1Maastricht University Medical Center, Maastricht, Netherlands O29 MULTIKINASES INHIBITOR IMPAIRING VASCULATURE FACILITATES THE IMMUNE RESPONSIVENESS AGAINST LEUKEMIA BY DECREASING THE POTENTIAL OF REGULATORY CELLS Emilia Jaskuła 1, Janusz Lange 2, Mariola Sedzimirska 2, Helena Pakos 2, Michalina Krydel 2, Jolanta Bochenska 2, Iwona Maszko-Wodzinska 2, Andrzej Lange 1 1L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences/ Lower Silesian Center for Cellular Transplantation with National Bone Marrow Donor Registry, Wroclaw, Poland - 2Lower Silesian Center for Cellular Transplantation with National Bone Marrow Donor Registry, Wroclaw, Poland O30 DONOR/RECIPIENT IL6 GENOTYPE IS NOT ASSOCIATED WITH SERUM PROFILE OF INFLAMMATION-ASSOCIATED MOLECULES IN PATIENTS AFTER ALLOGENEIC HAEMATOPOIETIC STEM CELL TRANSPLANTATION Frantisek Mrazek 1, Petra Schneiderova 1, Ludek Raida 1, Eva Kriegova 1, Adam Kuba 1, Martin Petrek 1, Zuzana Ambruzova 1 1Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic
THURSDAY O31 FIRST PILOT STUDY ON THE EFFICACY OF INTRAVENOUS IMMUNOGLOBULINS (IVIG) IN BEHCET PATIENTS: IMPROVEMENT OF DISEASE ACTIVITY INDEX AND INFLAMMATORY MARKERS Martina Finocchi 1, Giacomo Emmi 1, Elena Silvestri 1, Annalisa De Silvestri 2, Carmine Tinelli 2 Cristina Capittini 2 1Careggi University Hospital, University of Florence, Florence, Italy - 2IRCCS Policlinico San Matteo Foundation, Pavia, Italy O32 VACCINATION WITH A PNEUMOCOCCAL CONJUGATE VACCINE DOES NOT INDUCE HLA ANTIBODIES IN KIDNEY TRANSPLANT RECIPIENTS Monika Lindemann 1, Simon Heckel 2, Benjamin Wilde 3, Peter A. Horn 1, Falko M. Heinemann 1, Oliver Witzke 4 1Institute for Transfusion Medicine, University Hospital, Essen, Germany - 2Institute for Transfusion Medicine, Department of Infectious Diseases, Department of Nephrology, University Hospital, Essen, Germany - 3Department of Nephrology, University Hospital, Essen, Germany - 4Department of Infectious Diseases, University Hospital, Essen, Germany
40 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Thursday 10 May 2018
PARALLEL SESSIONS MOSAICI 2 ROOM - PALAZZO CASINÒ (3rd FLOOR) 14:40-16:10 Oral Session 4: Haematopoietic Stem Cell Transplantation Chairpersons: Manuela Testi, Jean Villard O33 BETTER HLA MATCHING AS REVEALED ONLY BY ULTRA-HIGH RESOLUTION HLA TYPING RESULTS IN SUPERIOR OVERALL SURVIVAL Neema P. Mayor 1, James D. Hayhurst 2, Thomas R. Turner 1, Richard M. Szydlo 3, Bronwen E. Shaw 4, Will P. Bultitude 1, Jex- Ray Sayno 2, Franco Tavarozzi 2, Katy Latham 2, Chloe Anthias 5, James Robinson 1, Henny Braund 2, Robert Danby 6, Julia Perry 7, Marie C. Wilson 8, Adrian J. Bloor 9, Andrew Clark 10, Stephen MacKinnon 11, David I. Marks 12, Antonio Pagliuca 13, Michael N. Potter 14, Victoria T. Potter 13, Nigel H. Russell 15, Kirsty J. Thomson 11, J. Alejandro Madrigal 1, Steven GE. Marsh 1 1Anthony Nolan Research Institute & UCL Cancer Institute, London, United Kingdom (Great Britain) - 2Anthony Nolan Research Institute, London, United Kingdom (Great Britain) - 3Anthony Nolan Research Institute & Imperial College, London, United Kingdom (Great Britain) - 4CIBMTR and Froedtert & the Medical College of Wisconsin, Milwaukee, United States of America - 5Anthony Nolan Research Institute & Royal Marsden NHS Foundation Trust, London, United Kingdom (Great Britain) - 6Anthony Nolan Research Institute & Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, London, United Kingdom (Great Britain) - 7British Society of Blood and Marrow Transplantation (BSBMT), London, United Kingdom (Great Britain) - 8Anthony Nolan Research Institute & British Society of Blood and Marrow Transplantation (BSBMT), London, United Kingdom (Great Britain) - 9The Christie NHS Foundation Trust, Manchester, United Kingdom (Great Britain) - 10West of Scotland Cancer Centre, Gartnavel Hospital, Glasgow, United Kingdom (Great Britain) - 11University College London Hospitals, London, United Kingdom (Great Britain) - 12University Hospitals Bristol NHS Foundation Trust, Bristol, THURSDAY United Kingdom (Great Britain) - 13Kings College Hospital, London, United Kingdom (Great Britain) - 14Royal Marsden NHS Foundation Trust, Sutton, United Kingdom (Great Britain) - 15Nottingham University Hospital, Nottingham, United Kingdom (Great Britain) O34 INVESTIGATING THE RECONSTITUTION OF THE T LYMPHOCYTE REPERTOIRE BY HIGH THROUGHPUT SEQUENCING AT ONE YEAR FOLLOWING HAEMATOPOIETIC STEM CELL TRANSPLANTATION IN A LARGE COHORT OF PATIENTS FROM SWITZERLAND Stéphane Buhler 1, Florence Studer-Bettens 1, Carole Dantin 1, Sylvie Ferrari-Lacraz 1, Yves Chalandon 1, Jean Villard 1 1Geneva University Hospitals, Geneva, Switzerland O35 DISSECTING GENETIC CONTROL OF HLA-DPB1 EXPRESSION AND ITS RELATION TO STRUCTURAL MISMATCH MODELS IN HEMATOPOIETIC STEM CELL TRANSPLANTATION Thuja Meurer 1, Esteban Arrieta Bolaños 1, Maximilian Metzing 1, Mona Langer 2, Peter van Balen 3, Frederick Falkenburg 3, Dietrich W. Beelen 4, Peter A. Horn 2, Katharina Fleischhauer 1, Pietro Crivello 1 1Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany - 2Institute for Transfusion Medicine, University Hospital Essen, Essen, Germany - 3Department of Hematology, Leiden University Medical Center, Leiden, Netherlands - 4Department of Bone Marrow Transplantation, West German Cancer Center, University Hospital Essen, Essen, Germany
41 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Thursday 10 May 2018
PARALLEL SESSIONS MOSAICI 2 ROOM - PALAZZO CASINÒ (3rd FLOOR) O36 HOW DONOR HLA MISMATCH, KIR-LIGAND MISMATCH AND NK CELL LICENSING MODELS AFFECT LEUKAEMIA RELAPSE IN HAEMATOPOIETIC STEM CELL TRANSPLANT RECIPIENTS Elzbieta Graczyk-Pol 1, Marta Rogatko-Koros 1, Klaudia Nestorowicz 1, Slawomir Gwozdowicz 1, Renata Mika-Witkowska 1, Daria Pawliczak 1, Marta Zubala 1, Joanna Dziopa 1, Urszula Szlendak 1, Agnieszka Witkowska 1, Agnieszka Tomaszewska 1, Barbara Nasilowska-Adamska 1, Andrzej Szczepinski 1, Michal Wojcik 1, Kazimierz Halaburda 1, Jacek Nowak 1 1Institute of Hematology and Transfusion Medicine, Warsaw, Poland O37 INVESTIGATING THE IMPACT OF PATIENTS’ NON-SHARED HLA-C ALLOTYPE EXPRESSION LEVELS IN A 9/10 SINGLE HLA-C MISMATCHED UNRELATED HSCT SETTING USING AN HLA-C EXPRESSION PROXY MODEL Chrysanthi Tsamadou 1, Daniel Furst 1, Dietger Niederwieser 2, Donald Bunjes 3, Christine Neuchel 1, Martin Gramatzki 4, Renate Arnold 5, Eva Wagner 6, Hermann Einsele 7, Hubert Schrezenmeier 1, Joannis Mytilineos 1 1German Red Cross Blood Transfusion Service, Baden-Wuerttemberg Hessen, Ulm, Germany and Institute of Transfusion Medicine, University of Ulm, Ulm, Germany - 2University of Leipzig, Leipzig, Germany - 3University of Ulm, Ulm, Germany - 4University of Kiel, Kiel, Germany - 5Charité Campus Virchow Berlin, Ulm, Germany - 6Johannes Gutenberg-University Mainz, Mainz, Germany - 7University Hospital Würzburg, Würzburg, Germany O38 MICRORNA EXPRESSION LEVELS IN CUTANEOUS ACUTE GRAFT-VERSUS HOST DISEASE Sadaf Atarod 1, Louis A. Bibby 2, Jean Norden 2, Anne Janin 3, Philippe Ratajczak 3, Clare Lendrem 2, Kim F. Pearce 2, Xiao-nong Wang 2, Steven O’Reilly 4, Jacob M. Van Laar 5, Matthew Collin 2, Anne M. Dickinson 2, Rachel E. Crossland 2 1Boston University and Boston Medical Center, Boston, United States of America - 2Newcastle University, Newcastle upon THURSDAY Tyne, United Kingdom (Great Britain) - 3Université Paris Diderot, Paris, France - 4Northumbria University, Newcastle upon Tyne, United Kingdom (Great Britain) - 5Utrecht University, Utrecht, Netherlands O39 SINGLE HAPLOTYPE ADMIXTURE MODELS USING LARGE SCALE HLA GENOTYPES TO REPRODUCE HUMAN ADMIXTURE Yoram Louzoun 1, Alexandra Litniski 1, Abeer Madbouly 2, Michael Halagan 2, Martin Maiers 3 1Bar Ilan University, Ramat Gan, Israel - 2NMDP, Minneapolis, United States of America - 3National Marrow Donor Program, Minneapolis, MN, United States of America O40 QUANTITATIVE PCR-BASED CHIMERISM MONITORING IN BONE MARROW OR PERIPHERAL BLOOD TO PREDICT LEUKAEMIA RELAPSE IN HIGH-RISK PATIENTS: FINAL RESULTS OF THE KIM-PB PROSPECTIVE STUDY Valentina Gambacorta 1, Riccardo Parolini 1, Elisabetta Xue 1, Raffaella Greco 1, Evelien Bouwmans 2, Cristina Toffalori 1, Fabio Giglio 1, Andrea Assanelli 1, Maria Teresa Lupo Stanghellini 1, Alessandro Ambrosi 3, Wietse Mulder 2, Consuelo Corti 1, Jacopo Peccatori 1, Fabio Ciceri 1, Luca Vago 1 1San Raffaele Scientific Institute, Milano, Italy -2 GenDx, Utrecht, Netherlands - 3University Vita-Salute San Raffaele, Milano, Italy
42 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Thursday 10 May 2018
PARALLEL SESSIONS PERLA ROOM - PALAZZO CASINÒ (1st FLOOR) 14:40-16:10 Teaching Session 2 Clinical impact of de-novo HLA antibodies in solid organ transplantation Antonina Piazza, David Turner • The clinical relevance of de novo HLA antibodies in renal transplantation Antonina Piazza • The clinical relevance of de novo HLA antibodies in heart transplantation Martin Howell • The clinical relevance of de novo HLA antibodies in pancreas and islet transplantation David Turner • Q&A THURSDAY 16:10-16:30 Coffee break & Poster viewing PALAZZO CASINÒ
43 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Thursday 10 May 2018
PLENARY SESSION 2 AUDITORIUM - PALAZZO CINEMA Solid organ transplantation Chairpersons: Antonio Amoroso, Joannis Mytilineos 16:30-17:00 T regulatory cell based therapy in promoting tolerance solid organ transplantation Giovanna Lombardi 17:00-17:30 Desensitization in SOT Christophe M.F. Legendre 17:30-18:00 Novel Biomarkers for allograft rejection in SOT Minnie M. Sarwal
PALAZZO DEL CASINÒ (3rd FLOOR) 18:00-20:00 Scientific Poster Reception (Sponsored by One Lambda and Lagitre, srl) THURSDAY
44 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Friday 11 May 2018
PLENARY SESSION 3 AUDITORIUM - PALAZZO CINEMA HSCT Current clinical perspectives Chairpersons: Luca Vago, Lotte Wieten 8:30-9:00 Haplo settings or impact of non shared haplotype on haplotransplant Leonido Luznik 9:00-9:30 Adoptive immunotherapies in HSCT Chiara Bonini 9:30-10:00 Tregs in HSCT Silvia Gregori
10:00-10:20 Coffee break & Poster viewing PALAZZO CASINÒ
PARALLEL SESSIONS MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR) 10:20-11:50 Oral Session 5: Solid Organ Transplantation Chairpersons: Franco Papola, Dave L. Roelen
O41 A NEW TOOL FOR QUANTIFICATION OF THE DONOR HLA-SPECIFIC MEMORY B CELL FRIDAY REPERTOIRE IN IMMUNIZED PATIENTS Gonca E. Karahan 1, Yvonne J.H. de Vaal 1, Juliette Krop 1, Caroline Wehmeier 1, Dave L. Roelen 1, Frans H.J. Claas 1, Sebastiaan Heidt 1 1Leiden University Medical Center, Leiden, Netherlands O42 ROLE OF HLA-E-RESTRICTED CD8+ T CELLS IN TRANSPLANTATION Gabriella Pietra 1, Selene Ottonello 1, Irene Cossu 2, Lucy C. Sullivan 3, Michela Falco 4, Maria Christina Mingari 1, Lorenzo Moretta 5 1University of Genova, Genova, Italy - 2IRCCS Ospedale Policlinico San Martino, Genova, Italy - 3University of Melbourne, Melbourne, Australia - 4Laboratory of Clinical and Experimental Immunology, Giannina Gaslini Institute, Genova, Italy - 5Ospedale Pedriatico Bambino Gesù, Roma, Italy
45 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Friday 11 May 2018
PARALLEL SESSIONS MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR) O43 ENDOTHELIAL-EPITHELIAL-RELATED TRANSCRIPTIONAL LEVELS IN ACUTE REJECTION BIOPSIES OF KIDNEY TRANSPLANT RECIPIENTS ARE PREDICTIVE FOR A WORSE RESPONSE TO STEROID TREATMENT Jianxin Yang 1, Marijke J. Spruyt-Gerritse 1, Darius Soonawala 1, Geert W. Haasnoot 1, Hans W. de Fijter 1, Marlies E.J. Reinders 1, Marian C. Clahsen 2, Frans H.J. Claas 1, Michael Eikmans 1 1Leiden University Medical Center, Leiden, Netherlands - 2Erasmus Medical Center, Rotterdam, Netherlands O44 KIDNEY TRANSPLANTED PATIENTS WITH OPERATIONAL TOLERANCE HAVE INCREASED FREQUENCIES OF CD19+CD1D+CD5+ SUPPRESSOR B CELLS AND HAVE A POSITIVE CORRELATION WITH THE PERCENTAGE OF TOTAL B CELLS Cristian M. Alvarez 1, Christian Morath 2, Marlon Castrillon 1, Daniel Alzate 1, Gerhard Opelz 2, Martin Zeier 2, Caner Süsal 2 1Universidad de Antioquia, Medellin, Colombia - 2University of Heidelberg, Heidelberg, Germany O45 HLA EPITOPE MATCHING OF KIDNEY TRANSPLANTS PREDICTS ANTIBODY- AND CELL- MEDIATED REJECTION Nils Lachmann 1, Oliver Staeck 1, Matthias Niemann 2, Klemens Budde 1, E. Spierings 3, Constanze Schönemann 1 1Charité - Universitätsmedizin Berlin, Berlin, Germany - 2PIRCHE AG, Berlin, Germany - 3University Medical Center Utrecht, Utrecht, Netherlands O46 STUDY OF IMMUNOLOGICAL AND IMMUNOGENIC RISK FACTORS FOR BKV REPLICATION AFTER RENAL TRANSPLANTATION Snezhina Mihaylova 1, Atanaska Georgieva 2, Yana Krasteva 2, Anastasya Mihaylova 1, Tsvetelin Lukanov 2, Valentina Atanasova 2, Luisa Hristova 2, Emil Paskalev 1, Elissaveta Naumova 1 1Medical University Sofia, University Hospital Alexandrovska, Sofia, Bulgaria 2- University Hospital Alexandrovska, Sofia, Bulgaria O47 DIFFERENCES FOR T-CELLS SUBTYPES IN ASPIRATION BIOPSIES OF KIDNEY TRANSPLANT
FRIDAY PATIENTS UNDER POLYCLONAL AND MONOCLONAL IMMUNOSUPPRESSIVE TREATMENTS Maria Paula DP. Xavier 1, Maria Conceição Magalhães 2, Susana Sampaio-Norton 3, Tiago Guimarães 2, José Gerardo Oliveira 4 1Instituto Português do Sangue e da Transplantação, Porto, Portugal - 2Centro Hospitalar S. João, Serviço Patologia Clínica, Porto, Portugal - 3Hospital S. João, Serviço Nefrologia, Porto, Portugal - 4Faculdade Medicina Porto, Hospital S. João, Porto, Portugal O48 IMPACT OF HLA-E*01:03 ALLELE CARRIER STATUS AND NKG2C ALLELE DELETION ON THE RISK OF CMV INFECTION AFTER RENAL TRANSPLANTATION Hana Guberina 1, Fabiola da Silva Nardi 1, Rafael Tomoya Michita 1, Sebastian Dolff 1, Anja Gäckler 1, Falko M. Heinemann 1, Benjamin Wilde 1, Mirko Trilling 1, Peter A. Horn 1, Andreas Kribben 1, Oliver Witzke 1, Vera Rebmann 1 1University Hospital Essen, University Duisburg-Essen, Essen, Germany
46 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Friday 11 May 2018
PARALLEL SESSIONS MOSAICI 2 ROOM - PALAZZO CASINÒ (3rd FLOOR) 10:20-11:50 Oral Session 6: NK and Miscellaneous Chairpersons: Benedetta Mazzi, Caner Süsal O49 IMPACT OF KIR ALLELE POLYMORPHISM ON THE STRUCTURE AND THE FUNCTION OF KIR2D NK CELL REPERTOIRE Katia Gagne 1, Bercelin Maniagou 2, Léa Dubreuil 2, Gaelle David 2, Nolwenn Legrand 2, Catherine Willem 2, Christelle Retiere 2 1Blood Bank EFS; CRCINA; Labex Transplantex, Nantes, France - 2Blood Bank EFS; CRCINA; Nantes, France O50 THE ROLE OF T CELL RECEPTOR CROSS-REACTIVITY IN HUMAN DISEASES Nicole Mifsud 1, Louise Rowntree 1, Lloyd D’Orsogna 2, Heleen van den Heuvel 3, Frans Claas 4, Patricia Illing 1, Stephanie Gras 1, Tom Kotsimbos 5, Anthony Purcell 1 1Monash University, Clayton, Australia - 2Fiona Stanley Hospital, Perth, Australia - 3Leiden University Medical Centre/Monash University, Leiden, Netherlands - 4Leiden University Medical Centre, Leiden, Netherlands - 5The Alfred Hospital/Monash University, Melbourne, Australia O51 THE GENETIC IMBALANCE AMONG HLA LIGANDS FOR INHIBITORY KIR3D RECEPTORS IN KAWASAKI CHILDREN: CLUES FOR ETIOPATHOGENESIS Cristina Capittini 1, Annalisa De Silvestri 1, Grazia Bossi 1, Savina Mannarino 1, Annamaria A. Pasi 1, Carmine Tinelli 1, Miryam Martinetti 1, Giacomo Emmi 2 1IRCCS Policlinico San Matteo Foundation, Pavia, Italy - 2Careggi University Hospital, University of Florence, Florence, Italy O52 KIR HAPLOTYPES DEFINED BY THEIR TRANSCRIPTOMES Jesse Bruijnesteijn 1, Marit K. H. Van der Wiel 1, Wendy Swelsen 2, Nel Otting 3, Annemiek J. M. de Vos-Rouweler 3, Diënne Elferink 4, Gaby G.M. Doxiadis 3, Neubury M. Lardy 2, Natasja G. De Groot 3, Ronald E. Bontrop 3 1BPRC, Rijswijk, Netherlands - 2Sanquin, Amsterdam, Netherlands - 3Biomedical Primate Research Centre, Rijswijk, Netherlands - 4LUMC, Leiden, Netherlands FRIDAY O53 FUNCTIONAL ANALYSIS OF SOLUBLE NKG2D LIGAND EXPRESSION IN UMBILICAL CORD BLOOD PLASMA REVEALS ACTIVATING POTENTIAL OF SOLUBLE MICA-129VAL VARIANTS Steven T. Cox 1, Robert Danby 1, Diana Hernandez 1, Alejandro Madrigal 1, Aurore Saudemont 1 1Anthony Nolan Research Institute, London, United Kingdom (Great Britain) O54 VITREOUS CRYOPRESERVATION OF HLA-MATCHED VASCULAR GRAFTS UTILIZING THE DECELLULARIZED HUMAN UMBILICAL ARTERY Panagiotis Mallis 1, Efstathios Michalopoulos 1, Michalis Katsimpoulas 2, Amalia Dinou 1, Aggeliki Papapanagiotou 3, Maria Spyropoulou-Vlachou 4, Catherine Stavropoulos-Giokas 1 1Hellenic Cord Blood Bank-Biomedical Research Foundation Of the Academy of Athens, Athens, Greece - 2Biomedical Research Foundation Of the Academy of Athens, Athens, Greece - 3National and Kapodistrian University of Athens, Athens, Greece - 4Alexandra General Hospital of Athens, Athens, Greece
47 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Friday 11 May 2018
PARALLEL SESSIONS MOSAICI 2 ROOM - PALAZZO CASINÒ (3rd FLOOR) O55 GENE EXPRESSION PROFILING REVEALS THE MOLECULAR SIGNATURE OF SEVERE CARBAMAZEPINE-INDUCED HYPERSENSITIVITY REACTIONS Nicole Mifsud 1, Alison Anderson 2, Patricia Illing 1, Patrick Kwan 2, Anthony Purcell 1 1Monash University, Clayton, Australia - 2Royal Melbourne Hospital/University of Melbourne, Parkville, Australia O56 HLA-G SELECTS PEPTIDES TISSUE SPECIFIC AND DISPLAYS EXCEPTIONAL TARGETS FOR IMMUNE EVASION Alexander A. Celik 1, Gwendolin S. Simper 1, Trevor Huyton 2, Wiebke Hiemisch 1, Rainer Blasczyk 1, Christina Bade-Doeding 1 1Hannover Medical School, Hannover, Germany - 2Max Planck Institute, Göttingen, Germany
PARALLEL SESSIONS PERLA ROOM - PALAZZO CASINÒ (1st FLOOR) 10:20-11:50 Teaching Session 3 Tools for a successful HSCT: evaluation of HLA allele frequencies, anti-HLA antibodies, structural and expression models for permissive mismatches Marcelo A. Fernández-Viña, Katharina Fleischhauer • Allele and haplotype frequencies: How variation affects donor searches • Anti-HLA antibodies: Role of DSA in HLA mismatched transplantation FRIDAY • Coding and non-coding HLA variation: Relationship between T-cell epitopes and HLA expression levels for permissive mismatches in HSCT
48 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Friday 11 May 2018
LUNCHEON SESSIONS MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR) 12:00-13:00 Luncheon Session - Bag Health Care First experiences with the HISTO SPOT® HLA AB test for automated antibody diagnostics John Smith, PhD, FRCPath HCS Consultant Head of Tissue Typing Service, Heart Science Centre, Harefield Hospital, Harefield, UK Evaluation of the HISTO SPOT® HLA AB test in comparison to a Luminex SA Test Ing. Murielle Verboom Medizinische Hochschule Hannover, Institute of Transfusion Medicine, Transplantation Immunology, Hannover, Germany
PERLA ROOM - PALAZZO CASINÒ (1st FLOOR) 12:00-13:00 Luncheon Session - One Lambda DSA Flow Cytometry Crossmatching… The New Frontier Cathi Murphey, Half, Ph.D Director, Histocompatibility and Immunogenetics Laboratory Southwest Immunodiagnostics, Inc San Antonio, Texas
13:00-13:30 Lunch
13:30-14:30 Luncheon Session - One Lambda FRIDAY LinkSēq™ SABR HLA Typing Kit resolution and HLA specific antibodies identification using the single antigen technology Julie Jouffrey Medical Engineer Laboratoire d’Immunologie et Histocompatibilité Hôpital Saint Louis Paris, France
49 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Friday 11 May 2018
LUNCHEON SESSIONS MOSAICI 2 ROOM - PALAZZO CASINÒ (3rd FLOOR) 13:30-14:30 Luncheon Session - Histogenetics New Horizons in HLA Typing and Haplotyping: Revolution in HLA Genomics Nezih Cereb, MD - CEO and Co-Founder Histogenetics
SPECIAL JOINT SESSION AUDITORIUM - PALAZZO CINEMA WMDA and EFI Chairpersons: Lydia Foeken, Elissaveta Naumova, Nicoletta Sacchi 14:40-15:10 Past, Present and Future of unrelated Donor registries Lydia Foeken 15:10-15:40 Pharma-economics of CB banking in the haplo era Sergio Luis Querol-Giner 15:40-16:10 How to choose the best unrelated HSC donor? Carolyn Katovich Hurley FRIDAY
50 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Friday 11 May 2018
PARALLEL SESSIONS MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR) 14:40-16:10 Oral Session 7: Reproduction, Autoimmunity, Infection & Cancer Chairpersons: Andrea Bontadini, Antonio Martinho O57 AN ALTERNATIVELY SPLICED ISOFORM OF THE HUMAN LEUKOCYTE ANTIGEN-DR ALPHA CHAIN IS ASSOCIATED WITH THE MULTIPLE SCLEROSIS RISK ALLELE HLA-DRB1*15:01 Vincent Damotte 1, Alessandro Didonna 1, Maneesh K. Misra 1, Noriko Isobe 1, Ravi Dandekar 1, Ashley H. Beecham 2, Stacy Cailler 1, Adam Santaniello 1, Jacob L. McCauley 2, Steven L. Hauser 1, Jorge R. Oksenberg 1, Jill A. Hollenbach 1 1University of California, San Francisco, San Francisco, United States of America - 2University of Miami, Miami, United States of America O58 HELLP SYNDROME IS ASSOCIATED WITH MHC GENES IN A FINNISH POPULATION A. Inkeri Lokki 1, Jenni Heikkinen-Eloranta 2, Juha Sinisalo 2, Hannele Laivuori 3, Marja-Liisa Lokki 1 1University of Helsinki, Helsinki, Finland - 2University of Helsinki and Helsinki University Hospital, Helsinki, Finland - 3University of Tampere, Tampere, Finland O59 EXPRESSION QTLs WITH OPPOSING EFFECTS ON HLA-DR AND -DQ GENES ARE ASSOCIATED WITH AUTOIMMUNE DISORDERS: EVIDENCE FOR MIXED ISOTYPE HETERODIMER FORMATION? Sandeep K. Singh 1, Johannes Dapprich 2, Jacob L. McCauley 3, Mehmet Tevfik Dorak 4 1Ohio State University, Columbus, OH, United States of America - 2Generation Biotech, Lawrenceville, NJ, United States of America - 3University of Miami, John P. Hussman Institute for Human Genomics, Miami, FL, United States of America - 4Kingston University London, Kingston, United Kingdom (Great Britain) O60 HLA-DRB1*09:01 IS ASSOCIATED WITH A SEVERE ASTHMA OUTCOME IN THE CONSORTIUM ON ASTHMA AMONG AFRICAN-ANCESTRY POPULATIONS IN THE AMERICAS (CAAPA) 1, Sophie Limou 2, Michelle Daya 3, Nicholas Rafaels 3, Jill Hollenbach 4, Antoine Lizée 4, Estelle Geffard 1, Nicolas Vince FRIDAY Alexandre Walencik 5, Maria Pino-Yanes 6, Steven Salzberg 7, Daehwan Kim 7, Harold Watson 8, Leslie Lange 3, James Wilson 9, Terri Beaty 7, Margaret Taub 7, Ingo Ruczinski 7, Rasika Mathias 7, (CAAPA) Consortium on Asthma among African-ancestry Populations in the Americas 7, Kathleen Barnes 3, Dara Torgerson 4, Pierre-Antoine Gourraud 10 1INSERM, Université de Nantes, Nantes, France - 2INSERM, Université de Nantes, Ecole Centrale de Nantes, Nantes, France - 3University of Colorado, Aurora, CO, United States of America - 4University of California San Francisco, San Francisco, CA, United States of America - 5EFS Centre - Pays de la Loire, Nantes, France - 6Universidad de La Laguna, Santa Cruz de Tenerife, Spain - 7Johns Hopkins University, Baltimore, MD, United States of America - 8The University of the West Indies, Queen Elizabeth Hospital, Bridgetown, Barbados - 9University of Mississippi Medical Center, Jackson, MS, United States of America - 10INSERM, Université de Nantes, CHU de Nantes, Nantes, France
51 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Friday 11 May 2018
PARALLEL SESSIONS MOSAICI 1 ROOM - PALAZZO CASINÒ (3rd FLOOR) O61 NEXT GENERATION SEQUENCING OF BTNL2 REVEALS NOVEL ASSOCIATIONS WITH ACUTE CORONARY SYNDROME IN FINNISH POPULATION Marja Marchesani 1, Juha Sinisalo 2, Veikko Salomaa 3, Markus Perola 4, Markku S. Nieminen 5, Steven J. Mack 6, Marja-Liisa Lokki 1 1University of Helsinki, Helsinki, Finland - 2Helsinki University Hospital, Helsinki, Finland - 3National Institute for Health and Welfare, Helsinki, Finland - 4National Institute for Health and Welfare (THL), Helsinki, Finland - 5Helsinki University Central Hospital, Helsinki, Finland - 6Children’s Hospital Oakland Research Institute, United States of America O62 MACROPHAGE MIGRATION INHIBITORY FACTOR AND D-DOPACHROME TAUTOMERASE ARE POTENTIAL DISEASE SEVERITY MODIFIERS IN MALE MULTIPLE SCLEROSIS SUBJECTS Gil Benedek 1, Halina Offner 2, Jorge R. Oksenberg 3, Dennis Bourdette 2, Richard Bucala 4, Arthur A. Vandenbark 2 1Hadassah Medical Center, Jerusalem, Israel - 2Oregon Health & Science University, Portland, Oregon, United States of America - 3University of California, San Francisco, San Francisco, United States of America - 4Yale School of Medicine, New Haven, United States of America O63 FUNCTIONAL ANNOTATION OF THE CLUSTER OF SCHIZOPHRENIA RISK MARKERS IN THE EXTENDED HLA CLASS I REGION Sandeep K. Singh 1, Johannes Dapprich 2, Mehmet Tevfik Dorak 3 1Ohio State University, Columbus, OH, United States of America - 2Generation Biotech, Lawrenceville, NJ, United States of America - 3Kingston University London, Kingston, United Kingdom (Great Britain) O64 ASSOCIATION OF MICA POLYMORPHISM WITH MICA SERUM LEVELS AND CLINICAL OUTCOME OF ANTI-TNF THERAPY IN PATIENTS WITH RHEUMATOID ARTHRITIS Milena Iwaszko 1, Jerzy Świerkot 2, Marta Dratwa 1, Barbara Wysoczańska 1, Lucyna Korman 2, Katarzyna Kolossa 3, Sławomir Jeka 3, Piotr Wiland 2, Katarzyna Bogunia-Kubik 1 1Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland - 2Wrocław Medical University, Wrocław, Poland - 3Hospital University Number 2 Jana Biziela, Bydgoszcz, Poland FRIDAY
52 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Friday 11 May 2018
PARALLEL SESSIONS PERLA ROOM - PALAZZO CASINÒ (1st FLOOR) 14:40-16:10 Teaching Session 4 How to prepare for an inspection: demonstrating how quality standards are met Andrea Harmer, Luca Mascaretti Presenters: Milena Ivanova, Christien Voorter • Preparing for Packet A and Packet C inspection • Common deficiencies • How to meet molecular testing and main quality management standards • Use of the accreditation software • Q&A and best practices
16:10-16:30 Coffee break & Poster viewing PALAZZO CASINÒ FRIDAY
53 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Friday 11 May 2018
PLENARY SESSION 4 AUDITORIUM - PALAZZO CINEMA Immunogenetics beyond HLA Chairpersons: Marcel G.J. Tilanus, John Trowsdale 16:30-17:00 Immunogenetics in autoimmunity Francesco Cucca 17:00-17:30 Exploiting targeted (EPI) genome editing for therapeutic applications Angelo Lombardo 17:30-18:00 GWAS in multiple sclerosis Stephen James Sawcer
PERLA ROOM - PALAZZO CASINÒ (1st FLOOR) 18:00-19:30 EFI General Assembly FRIDAY
54 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Saturday 12 May 2018
AUDITORIUM - PALAZZO CINEMA 8:30-10:00 Best Abstract Session Chairpersons: Katharina Fleischhauer, Luca Mascaretti O1 THE ENIGMA OF HLA-MEDIATED ADVERSE DRUG REACTIONS: EPOXIDE BUT NOT CARBAMAZEPINE INDUCES THE BINDING OF HAPTENATED PEPTIDES TO HLA-B*15:02 Gwendolin S. Simper 1, Alexander A. Celik 1, Gia-Gia T. Hò1, Trevor Huyton 2, Joachim Kuhn 3, Rainer Blasczyk 1, Christina Bade-Doeding 1 1Hannover Medical School, Hannover, Germany - 2Max Planck Institute, Göttingen, Germany - 3Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Germany O2 IMMUNITY ON A KNIFES EDGE: SELF/NON-SELF DISCRIMINATION AND THE CO- EXPRESSION OF NATURAL KILLER CELL RECEPTORS FINELY TUNES T CELL RECEPTOR AFFINITY AND FUNCTION Lucy C. Sullivan 1, Christopher M. Harpur 1, Thi H.O. Nguyen 1, Abbie R. Kanagarajah1, Jacqueline M.L. Widjaja 1, Gabriella Pietra 2, Katherine Kedzierska 1, Karl-Johan Malmberg 3, Andrew G. Brooks 1 1University of Melbourne, Melbourne, Australia - 2University of Genoa, Genoa, Italy - 3Institute for Cancer Research, Oslo University Hospital, Oslo, Norway O3 INVISIBLE ORGANS MADE BY GENETIC ENGINEERING TO TURN OFF MHC PRIOR TO ALLOGENEIC TRANSPLANTATION PREVENT A PRO-INFLAMMATORY CYTOKINE RESPONSE IN THE RECIPIENT Constanca Figueiredo 1, Marco Carvalho-Oliveira 1, Chen Chen-Wacker 1, Klaus Höffler1 , Marc Kühnel 1, Katharina Jansson 1, Axel Haverich 1, Gregor Warnecke 1, Rainer Blasczyk 1 1Hannover Medical School, Hannover, Germany O4 THE ALLOTYPIC ARCHITECTURE OF HLA-B57 ALLOTYPES ALTERS PEPTIDE CONFORMATION TO REGULATE INHIBITION OF NK CELL ACTIVATION THROUGH KIR3DL1 Andrew G. Brooks 1, Philippa M. Saunders 1, Philip Pymm 2, Jacqueline ML. Widjaja 1, Jie Lin 1, Jamie Rossjohn 2, Julian P. Vivian 2 1Peter Doherty Institute, University of Melbourne, Melbourne, Australia - 2Monash University, Clayton, Australia O5 EPIGENOME-WIDE ASSOCIATION STUDY REVEALS IMMUNOGENETIC TARGETS OF DNA METHYLATION MODIFICATION BY HIV-1 Kevin Hoang 1, George Nelson 2, Elizabeth Binns-Roemer 2, Nicolas Vince 1, Pierre-Antoine Gourraud 3, James J. Goedert 4, Cheryl Winkler 2, 5
Sophie Limou SATURDAY 1INSERM, Université de Nantes, Nantes, France - 2Frederick National Laboratory, Frederick, MD, United States of America - 3INSERM, Université de Nantes, CHU de Nantes, Nantes, France - 4NIH/NCI, Bethesda, MD, United States of America - 5INSERM, Université de Nantes, Ecole Centrale de Nantes, Nantes, France
55 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Saturday 12 May 2018
AUDITORIUM - PALAZZO CINEMA O6 EXPLOITING CUTTING-EDGE TECHNOLOGIES TO ANALYZE LOSS OF HLA IN A GLOBAL MULTICENTRIC COHORT OF POST-TRANSPLANTATION RELAPSES: PRELIMINARY RESULTS FROM THE HLA LOSS COLLABORATIVE STUDY Luca Vago 1, Cristina Toffalori 1, Ahci Müberra 2, Vinzenz Lange 3, Kathrin Lange 3, Sonia Todaro 1, Karin Stempelmann 2, Andreas Heinold 2, Friedrich Stölzel 4, Miguel Waterhouse 5, Rainer Claus 5, Ketevan Gendzekhadze 6, Masahiro Onozawa 7, Raynier Devillier 8, Ruoping Tang 9, Maayan Ulman 10, Dejan Lazarevic 1, Maria Teresa Lupo Stanghellini 1, Jacopo Peccatori 1, Nina K. Steckel 2, Peter A. Horn 2, Alessandra Picardi 11, Sara Manetta 12, Jose L. Pinana 13, Jaimie Sanz 13, Brian Schaffer 14, William Arcese 11, Guillermo Sanz 13, Benedetto Bruno 12, Massimo Pini 15, Guido Kobbe 16, Katharine C. Hsu 14, Monzr Al Malki 6, Takanori Teshima 7, Nicolaus Kroeger 17, Jurgen Finke 5, Arnon Nagler 10, Didier Blaise 8, Mohamad Mohty 9, Martin Bornhauser 4, Dietrich W. Beelen 2, Alexander Schmidt 3, Fabio Ciceri 1, Katharina Fleischhauer 2 1San Raffaele Scientific Institute, Milano, Italy -2 Essen University Hospital, Essen, Germany - 3DKMS Life Science Lab, Dresden, Germany - 4Technical University Dresden, Medical Clinic and Policlinic I, Dresden, Germany - 5University Medical Center Freiburg, Freiburg, Germany - 6City of Hope National Medical Center, Duarte, CA, United States of America - 7Hokkaido University, Faculty of Medicine, Sapporo, Japan - 8Institut Paoli-Calmettes, Marseille, France - 9Hopital Saint Antoine AP-HP, Paris, France - 10Chaim Sheba Medical Center, Tel-Hashomer and Tel-Aviv University, Tel Aviv, Israel - 11Tor Vergata University of Rome - Regional Transplant Center of Lazio, Roma, Italy - 12A.O.U. Città della Salute e della Scienza di Torino, Torino, Italy - 13Hospital Universitari i Politècnic La Fe, Valencia, Spain - 14Memorial Sloan Kettering Cancer Center, New York, NY, United States of America - 15A.O. SS Antonio e Biagio e C. Arrigo, Alessandria, Italy - 16Heinrich-Heine University, Dusseldorf, Germany - 17University Hospital Eppendorf, Hamburg, Germany O7 UNRAVELLING DYNAMIC CHANGES IN THE MATERNAL IMMUNE COMPARTMENT AT THE MATERNAL-FETAL INTERFACE DURING PREGNANCY BY MASS CYTOMETRY Anita van der Zwan 1, Vincent van Unen 1, Thomas Höllt 2, Hanneke J.M. Kapsenberg 1, Marie-Louise P. van der Hoorn 1, Merve Uyar-Mercankaya 1, Susana M. Chuva de Sousa Lopes 1, Frits Koning 1, Frans H.J. Claas 1, Sebastiaan Heidt 1 1Leiden University Medical Center, Leiden, Netherlands - 2Delft University of Technology, Delft, Netherlands O8 LOSS OF HLA-A IN ACUTE MYELOID LEUKEMIA TRANSMITTED BY THE DONOR TO LIVER AND KIDNEY GRAFT RECIPIENTS Luigi Marchionni 1, Anna Serra 2, Federico Genzano Besso 3, Silvia Deaglio 2, Piero Stratta 4, Monica Berrino 3, Francisco Lobo Pereira 1, Aleksei Stupniko 1, Gianluca Gaidano 4, Benedetto Bruno 2, Giuseppe Saglio 2, Antonio Amoroso 4 1Johns Hopkins University, Baltimore, United States of America - 2University of Turin, Turin, Italy - 3Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Presidio Molinette, Torino, Italy - 4University of Eastern Piedomont, Novara, Italy 10:00-10:30 17th and 18th IHW reports SATURDAY The 17th International HLA & Immunogenetics Workshop 2017 Marcelo A. Fernández-Viña The 18th International HLA & Immunogenetics Workshop 2021 Eric Spierings
10:30-10:50 Coffee break
56 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Saturday 12 May 2018
PLENARY SESSION 5 AUDITORIUM - PALAZZO CINEMA New frontiers in immunogenetics Chairpersons: Elissaveta Naumova, David Turner 10:50-11:20 Single cell technologies Ido Amit 11:20-11:50 Immunopeptidome Markus Löffler 11:50-12:20 Neoantigens in cancer immunotherapy Derin Keskin
CLOSING CEREMONY AUDITORIUM - PALAZZO CINEMA Chairpersons: Valeria Miotti, Elissaveta Naumova 12:20-12:50 Closing Lecture Chairpersons: Carlo Carcassi, Valeria Miotti Leonardo da Vinci: the prototype of Art & Science man Pietro Cesare Marani 12.50-13.00 Jon van Rood Award and Best Abstract Awards Committee Chair: Frans H.J. Claas 13.00-13.10 Best Poster Awards Committee: Marco Andreani, Carlo Carcassi, Luca Mascaretti, Sandra Tafulo, Hien Tran 13.10-13.20 EFI 2019, Lisbon SATURDAY Antonio Martinho
13.20-13.30 Closing Remarks
57 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) POSTER PRESENTATIONS
SOLID ORGAN TRANSPLANTATION P1 INTRA-GRAFT DETECTION OF ANTI-HLA ANTIBODIES AND TRANSPLANT FAILURE: A REPORT OF FOUR CASES Elena Longhi 1, Angela Nocco 1, Miriam Ramondetta 1, Viviana Sioli 2, Annalisa Innocente 2, Loretta Crespiatico 2, Mario Macchiagodena 2, Denise Bertola 2, Caterina Brambilla 2, Nicoletta Cagni 2, Massimo Cardillo 3 1Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy - 2IRCCS Maggiore Policlinico Hospital, Milano, Italy - 3Fondazione IRCCS Ca’ Granda- Ospedale Maggiore Policlinico, Milan, Italy P2 IMPACT OF FC-GAMMA RECEPTORS IIIA [158F/V] POLYMORPHISMS ON CHRONIC LUNG ALLOGRAFT DYSFUNCTION (CLAD) AND PATIENTS SURVIVAL AFTER LUNG TRANSPLANTATION Christophe Picard 1, Julie Di Cristofaro 1, Pascale Paul 2, Agnes Basire 3, Anderson Loundou 4, Mattieu Pelardy 3 Luc Lyonnet 5, Coralie Frassati 3, Pascal Thomas 6 Carine Gomez 6 Martine Reynaud-Gaubert 6 1UMR7268 AMU CNRS EFS, MARSEILLE, France - 2INSERM 1076, Aix Marseille Université, Assistance Publique Hopitaux de Marseille, Marseille, France - 3EFS PACAC, Marseille, France - 4University hospital Marseille, Marseille, France - 5Assistance Publique hopitaux de Marseille, Hematology Unit, Marseille, France - 6APHM-Hôpital Nord, Marseille, France P3 APPLICATION OF THE SINGLE REGIONAL LIST FOR KIDNEY TRANSPLANTATION IN SICILY. CRITICALITY AND ADVANTAGES Serena Mistretta 1, Rosalba Bavetta 1, Floriana Bruno 1, Giuseppe Davì 1, Valentina Cappuzzo 1, Francesco Ingrassia 1, Maria Igea Vega 1, Maria Blando 1, Bruna Piazza 2, Raimondo Marcenò 1 1Lab. Regionale di Tipizzazione Tessutale ed Immunologia dei Trapianti, Palermo, Italy - 2Centro Regionale Trapianti (CRT) Sicilia, Palermo, Italy P4 KIDNEY TRANSPLANT FOR HIGHLY SENSITISED PATIENTS ON THE SICILIAN WAITING LIST: REPORT ON THE FIRST TRANSPLANTED PATIENT Serena Mistretta 1, Rosalba Bavetta 1, Floriana Bruno 1, Giuseppe Davì 1, Valentina Cappuzzo 1, Francesco Ingrassia 1, Maria Igea Vega 1, Maria Blando 1, Valentina Vinti 2, Antonio Amato 2, Flavia Caputo 2, Raimondo Marcenò1 1Lab. Regionale di Tipizzazione Tessutale ed Immunologia dei Trapianti, Palermo, Italy - 2Nefrologia con Trapianto, Palermo, Italy P5 OMISSION OF THE PROSPECTIVE CROSSMATCH IN DECEASED DONOR KIDNEY TRANSPLANTATION AND INCIDENCE OF EARLY AMR David M. Turner 1, Richard Battle 1, Angus Turnbull 2, Lorna Henderson 2 1Scottish National Blood Transfusion Service, Edinburgh, United Kingdom (Great Britain) - 2Transplant Unit, Edinburgh, United Kingdom (Great Britain) P6 BAFF RS12874404 SNP DOES NOT INFLUENCE ANTI-HLA ANTIBODY PRODUCTION IN KIDNEY RECIPIENTS Silvia Alizzi 1, Pamela M. Moschini 1, Maristella Pitzalis 2, Maristella Steri 2, Cristiana Caorsi 3, Claudia Maria Rosso 4, Silvia Deaglio 5, Francesco Cucca 2, Antonio Amoroso 5 1Città della Salute e della Scienza Hospital, Torino, Italy - 2Consiglio Nazionale delle Ricerche, Cagliari, Italy - 3AOU Città della Salute e della Scienza di Torino, Torino, Italy - 4Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, POSTER Presidio Molinette, Torino, Italy - 5University of Turin, Torino, Italy
58 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P7 DETERMINATION OF LEUKOCYTE ANTIBODIES IN PATIENTS WAITING FOR KIDNEY TRANSPLANTATION IN THE REPUBLIC OF KAZAKHSTAN Aida Turganbekova 1, Zhandos Burkitbaev 1, Saniya Abdrakhmanova 1, Indira Ramilyeva 1, Dana Baimukasheva 1, Zhazira Saduakas 1, Perizat Zhunus 1 1Republic scientific and production center of transfusiology, Astana, Kazakhstan P8 THE IMPACT OF DE NOVO DONOR SPECIFIC ANTIBODIES AND HLA HISTOCOMPATIBILITY IN LONGTERM KIDNEY TRANSPLANTATION OUTCOME (UP TO 27 YEARS) Asimina Fylaktou 1, Efstratios Kasimatis 2, Theodoros Karampatakis 1, Maria Schoina 2, Aikaterini Anastasiou 1, Anna Boukla 1, Vasiliki Nikolaidou 1, Marianthi Papachristou 1, Theodoros Chronis 1, Aikaterini Papagianni 2 1National Peripheral Histocompatibility Center, Hippokration General Hospital, Thessaloniki, Greece - 2Kidney Department,Hippokration General Hospital, Thessaloniki, Greece P9 DONOR SPECIFIC ANTI-HLA IGA ANTIBODIES AND GRAFT SURVIVAL AFTER KIDNEY TRANSPLANTATION Marie-Luise Arnold 1, Christian Bach 2, Falko M. Heinemann 3, Andrea Dick 4, Bernd M. Spriewald 2 1Institute for Clinical Immunology, Department of Internal Medicine 3, Rheumatology and Immunology, Erlangen, Germany - 2Institute for Clinical Immunology, Department of Internal Medicine 5, Hematology and Oncology, Erlangen, Germany - 3Intitute for Transfusion Medicine, University Hospital Duisburg-Essen, Essen, Germany - 4Laboratory of Immunogenetics, Ludwig Maximilians University, Munich, Germany P10 RITUXIMAB INTERFERENCE IN B-CELL CROSSMATCH: A PROBLEM SOLVED Beatrice Bardy 1, Paolo Malvezzi 2, Lionel Rostaing 2, Dominique Masson 1 1EFS Rhone Alpes, La Tronche, France - 2CHU Grenoble Alpes, Grenoble, France P11 ANTIBODY-MEDIATED REJECTION AFTER LIVER TRANSPLANTATION - SELECTED IMMUNOLOGICAL PARAMETERS Antonij Slavcev 1, Zuzana Sekerkova 1, Barbora Kovandova 1, Eva Honsova 1, Sarka Valhova 1, Pavel Trunecka 1 1IKEM, Prague, Czech Republic P12 HIGHLY-SENSITIZED PATIENTS: MORE THAN ANTI-HLA ANTIBODIES Laura Riesco 1, Juan Irure 1, Emilio Rodrigo 1, Juan Calos Ruiz-San Millán 1, Marcos López-Hoyos 1, David San Segundo 1 1Marques de Valdecilla Universitary Hospital-IDIVAL, Santander, Spain P13 EFFICIENCY OF DONOR EXCHANGE PROGRAM AT KING FAISAL SPECIALIST HOSPITAL JEDDAH Ashraf Dada 1, Nabeela Al Baz 1, Hamad Bokhari 1 1Pathology & Laboratory Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia P14 CLINICAL RELEVANCE OF COMPLEMENT-DEPENDENT CYTOTOXICITY AS A SUPPORTING ASSAY IN THE KIDNEY PAIR EXCHANGE SETTING Ashraf Dada 1, Osama Al Suraihi 1, Nabeela Al Baz 1, Ahmad Bokhari 1 1Pathology & Laboratory Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia P15 EDTA TREATMENT WITH NORMAL GOAT SERUM (GS) BLOCKING REMOVES DR4/DR16 BUT NOT DP1/DP5 FALSE POSITIVE PATTERNS ON SINGLE ANTIGEN BEAD (SAB) HLA CLASS II ANTIBODY TESTING Kristina A. Davis 1, Maria Ramirez 1, Timothy Williams 1, Lena Kleyman 1, Gregory Simmons 1, Debra Schauss 1, 1 1 1 1 1 1 1 Abdul Abdulle , Nell Field , Samantha Fogel , Thomas Franks , Kelsey Makushik , Andrea Parkinson , Cory Peitsch , POSTER Cynthia Schall 1, Omar Moussa 1 1University of Michigan, Ann Arbor, United States of America
59 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P16 PATIENTS AWAITING KIDNEY TRANSPLANTATION ARE MORE FREQUENTLY CARRIERS OF THE RS763780 488G ALLELE THAT IS ASSOCIATED WITH HIGHER IL-17F SERUM LEVELS Malgorzata Kaminska 1, Wanda Niepieklo-Miniewska 1, Artur Nieszporek 1, Katarzyna Gebura 1, Katarzyna Bogunia-Kubik 1 1Hirszfeld Institute of Immunology and Experimental Therapy, Wroclaw, Poland P17 COMPARISON OF VIRTUAL AND CDC, FLOW, LUMINEX CROSS MATCH METHODS Derya Gulec 1, Tulay Kilicaslan Ayna 1, Asli Kocyigit Ozkizilcik 1, Asli Eldem 1, Burcu Cerci Gurbuz 1, Mustafa Soyoz 1 1Tepecik Training and Research Hospital, Izmir, Turkey P18 IN VITRO TGF-Β SECRETION CAPACITY OF STIMULATED PERIPHERAL BLOOD CELLS CORRELATES WITH THE OCCURRENCE OF OPPORTUNISTIC INFECTION IN LIVER AND KIDNEY TRANSPLANTATION Francisco Boix 1, Gema Gonzalez-Martinez 1, Rafael Alfaro 1, Jose Antonio Galian 1, Isabel Legaz 2, Maria R. Moya-Quiles 1, Alfredo Minguela 1, Jose A. Pons 1, Santiago Llorente 1, Manuel Muro 1 1Clinic University Hospital Virgen Arrixaca, Murcia, Spain - 2University of Murcia, Murcia, Spain P19 COMPARING INFERENCES DRAWN FROM INTERMEDIATE HLA TYPING TO HIGH RESOLUTION TYPING RESULTS - COULD IT BE AN INTERIM SOLUTION? A STUDY FROM A TERTIARY CARE MEDICAL INSTITUTION IN INDIA Sam A. Doss R 1, Siddharth Mittal 2, Mary P. Chacko 2, Dolly Daniel 2 1Christian Medical College & Hospital, Vellore, India - 2Christian Medical College, Vellore, India P20 UNEXPECTED FLOW CYTOMETRY CROSSMATCH REACTIVITY IN PATIENTS AWAITING KIDNEY TRANSPLANT Anastasiya Mihaylova 1, Petiya Yankova 1, Anzhela Antonova 2, Nevena Gesheva 2, Valentina Atanasova 2, Milena Ivanova-Shivarova 1, Elissaveta Naumova 1 1University Hospital Alexandrovska, Medical University, Sofia, Bulgaria -2 University Hospital Alexandrovska, Sofia, Bulgaria P21 ANALYSIS OF HLA ALLOREACTIVITY BASED ON PREDICTION OF HLA-DRB1 RESTRICTED T CELL EPITOPES Miriam Vilches-Moreno1, Cristina Abad-Molina 2, Antonio Nieto 1 1Hospital Puerta del Mar, Cádiz, Spain - 2Hospital Clínico Universitario de Valladolid, Valladolid, Spain P22 COMPARISON OF THE VIRTUAL CROSSMATCH VERSUS ACTUAL CROSSMATCH IN CADAVER DONOR KIDNEY TRANSPLANTATION Biserka Palfi1 , Natalija Martinez 1, Mirica Batarelo 1, Davorka Galenic 1, Kristina Kopic 1, Magdalena Svetec 1, Zorana Grubic 1, Renata Zunec 1 1University Hospital Centre Zagreb, Zagreb, Croatia P23 HLA-SPECIFIC ANTIBODIES DETECTED BY THE BEAD ARRAY TECHNIQUE CAN ACT AS SURROGATE MARKERS FOR T- AND B-CELL FLOW CROSSMATCHES Sabine Wenda 1, Daniela Koren 2, Ingrid Faé1, Gottfried F. Fischer 1 1Medical University Vienna, Vienna, Austria - 2General Hospital Vienna, Vienna, Austria P24 USING FLUORESCENCE INTENSITY LEVELS BY LUMINEX TO PREDICT CROSSMATCH BY CDC Cristina Abad-Molina 1, Miriam Vilches-Moreno 2, Israel Olivas-Martínez 3, Mario Cárdaba-Arranz 1, María Francisca González-Escribano 3 1Hospital Clínico Universitario de Valladolid, Valladolid, Spain - 2Hospital Puerta del Mar, Cádiz, Spain - 3Hospital Universitario POSTER Virgen del Rocío Sevilla, Spain
60 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P25 DEVELOPMENT OF SPECIFIC DONOR HLA ALLOANTIBODIES (DSAS) AFTER KIDNEY TRANSPLANTATION: A SINGLE CENTER EXPERIENCE Paola F. Zanelli 1, Roberta Merli 1, Sara Tedeschi 2, Ilaria Gandolfini2 , Umberto Maggiore 2, Adele Zanetti 1 1SSUO Immunogenetica dei Trapianti, Parma, Italy - 2SSUO Trapianti Rene - Pancreas, Parma, Italy P26 SYSTEMATIC REVIEW AND REMOVAL OF UNACCEPTABLE ANTIGENS SIGNIFICANTLY IMPROVES THE CHANCE OF A KIDNEY TRANSPLANT FOR HIGHLY SENSITISED PATIENTS. A SINGLE CENTRE APPROACH IN THE UK Sean B. Carey 1, Andrew Connor 1, Imran S. Saif 1, Sara Stacey 1, Linda Boorer 1, Mazen Mabrok 1, Kim Boswijk 1, Jamie Barwell 1, Anthony Poles 2 1Plymouth Hospitals, Plymouth, United Kingdom (Great Britain) - 2Plymouth Hospitals & Filton, Plymouth & Bristol, United Kingdom (Great Britain) P27 IMPACT OF ANTI-HLA-DP AND -DQA ANTIBODIES IN RENAL TRANSPLANTATION: A PRELIMINARY STUDY Paola F. Zanelli 1, Valentina Sgobba 1, Roberta Merli 1, Roberta Lamanna 1, Silvia Giuliodori 1, Magda Benecchi 1 1SSUO Immunogenetica dei Trapianti, Parma, Italy P28 FLOW CYTOMETRY CROSSMATCH: FCXM VS. FLOWDSA-XM Giuseppina Ozzella 1, Elvira Poggi 1, Antonio Giuseppe Bianculli 2, Damiano Colasante 2, Maria Rosaria Fazio 2, Annarita Manfreda 2, Silvia Sinopoli 2, Lucia Spano 2, Antonina Piazza 1 1National Council of Researches, IFT Unit of Rome S. Camillo Hospital - Regional Transplant Center of Lazio, Rome, Italy - 2Regional Transplant Center of Lazio, Rome, Italy P29 CORRELATION OF THE DE NOVO DONOR SPECIFIC ANTI-HLA ANTIBODY (DNDSA) EMERGENCE WITH IMMUNOSUPPRESSION AND 2-YEAR LIVER TRANSPLANTATION OUTCOME: A PROSPECTIVE STUDY Marianthi Papachristou 1, Asimina Fylaktou 1, Theodoros Karampatakis 1, Evaggelos Chologitas 2, Maria Daoudaki 3, Charalampos Zarras 1, Fani Makrovasili 1, Ioannis Fouzas 4 1National Peripheral Histocompatibility Center, Hippokration General Hospital, Thessaloniki, Greece - 21st Internal Medicine Department, Medical School, National Kapodistrian University of Athens, Athens, Greece - 3Biochemistry Laboratory, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece - 4Solid Organ Transplantation Center, Aristotle University of Thessaloniki, Medical School, Hippokration General Hospital, Thessaloniki, Greece P30 DISCOVERY OF A NOVEL HLA-B*08 NULL ALLELE IN A DANISH KIDNEY TRANSPLANT RECIPIENT Mette Christiansen 1, Pernille B. Koefoed-Nielsen 1, Bjarne K. Møller 1 1Aarhus University Hospital, Aarhus N, Denmark P31 THE ROLE OF LUMINEX-DETECTED HLA ANTIBODIES IN LONG-TERM OUTCOME OF KIDNEY TRANSPLANT: A SINGLE CENTER EXPERIENCE Serena Maria Passamonti 1, Antonino Cannavò1, Francesca Poli 1, Annalisa Innocente 1, Alejandro Espadas de Arias 1, Piergiorgio Messa 1, Mariano Ferraresso 1, Massimo Cardillo 1 1Fondazione IRCCS Ca’ Granda- Ospedale Maggiore Policlinico, Milan, Italy P32 INCIDENCE OF ANTI-DQ DONOR SPECIFIC ANTIBODY IN RENAL TRANSPLANT RECIPIENTS OF TERTIARY CARE HOSPITAL OF NORTH INDIA Mohit Chowdhry 1, RN Makroo 1, Yogita Thakur 1, Mandhata Singh 1, Manoj Mishra 1, Vandana Sharma 1 1Apollo Hospital, New Delhi, India POSTER
61 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P33 ANTIBODY PROFILE OF STEM CELL AND ORGAN TRANSPLANTATION PATIENTS IN A SINGLE CENTER Claudia Lehmann 1, Ramona Landgraf 1, Ilias Doxiadis 1 1Transfusion medicine, HLA-laboratory, Leipzig, Germany P34 OPTIMIZATION AND VALIDATION OF AN IGA HLA-SPECIFIC LUMINEX SINGLE ANTIGEN BEAD ASSAY Helena Car 1, Cynthia S.M. Kramer 1, Simone Brand-Schaaf 1, Gonca E. Karahan 1, Cees Van Kooten 2, Paul W.H.I. Parren 1, F.H.J. Claas 1, Dave L. Roelen 1, Sebastiaan Heidt 1 1Leiden University Medical Center, Leiden, Netherlands - 2LUMC, Leiden, Netherlands P35 REASSESSMENT OF T-LYMPHOCYTE CROSSMATCH RESULT PREDICTION FOR ANTI-HLA-C ANTIBODIES WITH SINGLE ANTIGEN FLOW BEADS ASSAYS Gwendaline Guidicelli 1, Mamy Ralazamahaleo 1, Charlene Bouthemy 1, Thoa Nong 2, Jar-How Lee 2, Jean-Luc Taupin 1, Jonathan Visentin 1 1Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France - 2One Lambda, Inc, Canoga Park, United States of America P36 DETECTION AND IDENTIFICATION OF ANTI-HLA ANTIBODIES IN PATIENTS ON THE WAITING LIST FOR KIDNEY TRANSPLANTATION Orjeta Bonaca 1, Eva Plesec 1, Katja Rotar 1, Blanka Vidan-Jeras 1 1Blood Transfusion Center of Slovenia, Ljubljana, Slovenia P37 AXL EXPRESSION IN MIXED LYMPHOCYTE REACTIONS IN A POPULATION OF KIDNEY TRANSPLANT PATIENTS Maria Paula DP. Xavier 1, Susana Sampaio-Norton 2, José Gerardo Oliveira 3 1Instituto Português do Sangue e da Transplantação, Porto, Portugal - 2Hospital S. João, Serviço Nefrologia, Porto, Portugal - 3Faculdade Medicina Porto, Hospital S João, Porto, Portugal P38 INVESTIGATION OF COSMC GENE DNA METHYLATION PROFILE AND EXPRESSION LEVEL IN IGA Sebahat U Akgul 1, Cigdem Kekik 1, Yasar K Caliskan 1, Egemen Cebeci 2, Erol Demir 1, Sonay Temurhan 1, Filiz Aydin 3, Fatma Oguz Savran 1 1Istanbul Faculty of Medicine, Istanbul, Turkey - 2Haseki Training and Research Hospital, Istanbul, Turkey - 3Istanbul Faculty of Medicine, Medical Biology Department, Istanbul, Turkey P39 BIOMARKER FOR PROGRESSION OF IGA NEPHROPATHY Sonay Temurhan 1, Sebahat U. Akgul 1, Cigdem Kekik 1, Yasar K. Caliskan 1, Yasemin Ozluk 1, Serra Ertan 1, Erol Demir 1, Halil Yazici 1, Aydin Turkmen 1, Isin Kilicarslan 1, Mehmet S Sever 1, Fatma Oguz Savran 1 1Istanbul Faculty of Medicine, Istanbul, Turkey POSTER
62 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P40 DECREASED GRAFT SURVIVAL OF RETRANSPLANTS CAN LARGELY BE EXPLAINED BY INCREASED HLA-IMMUNIZATION Elena G. Kamburova 1, B.W. Wisse 1, I. Joosten 2, W.A. Allebes 2, A. van der Meer 2, L.B. Hilbrands 2, M.C. Baas 2, Eric Spierings 1, C.E. Hack 1, F. van Reekum 1, A.D. van Zuilen 1, M.C. Verhaar 1, M.L. Bots 1, L. Plaisier 1, M.A.J. Seelen 3, J.S.F. Sanders 3, B.G. Hepkema 4, A.J. Lambeck 4, L.B. Bungener 4, C. Roozendaal 4, M.G.J. Tilanus 5, C.E. Voorter 5, L. Wieten 5, E. van Duijnhoven 5, M. Gelens 5, M. Christiaans 5, F. van Ittersum 6, A. Nurmohamed 6, N.M. Lardy 7, W.T. Swelsen 7, K.A.M.I. van der Pant 8, N.C. van der Weerd 8, I.J.M. ten Berge 8, F.J. Bemelman 8, A.J. Hoitsma 9, P.J.M. van der. Boog 10, J.W. de Fijter 10, M.G.H. Betjes 11, Sebastiaan Heidt 10, D.L. Roelen 10, F.H.J. Claas 10, H.G. Otten 1 1University Medical Center Utrecht, Utrecht, Netherlands - 2Radboud University Medical Center, Nijmegen, Netherlands - 3University Medical Center Groningen, Groningen, Netherlands - 4University of Groningen, University Medical Center Groningen, Groningen, Netherlands - 5Maastricht University Medical Center, Maastricht, Netherlands - 6VU University Medical Center, Amsterdam, Netherlands - 7Sanquin, Amsterdam, Netherlands - 8Academic Medical Center, Amsterdam, Amsterdam, Netherlands - 9NTS, Leiden, Netherlands - 10Leiden University Medical Center, Leiden, Netherlands - 11Erasmus Medical Center, Rotterdam, Rotterdam, Netherlands P41 HLA-DP ANTIBODY INCOMPATIBLE TRANSPLANTATION: A SINGLE CENTRE REVIEW Adrienne Seitz 1, Katherine Mounsey 1, Ruth Foster 1, Pamela Hughes 1, Richard Baker 1, Brendan Clark 1 1Leeds Teaching Hospitals NHS Trusts, Leeds, United Kingdom (Great Britain) P42 IGG SUBTYPES IDENTIFIED BY A FLOW CROSSMATCH ASSAY INCREASES SUCCESSFUL TRANSPLANTS IN SENSITIZED RECIPIENTS Prakash Rao 1, Deo Dayanand 1, David Baran 2, Mark Zucker 2, Jesus Almendral 3, Shamkant Mulgaonkar 4, Praveen Kandula 4 1NJ Sharing Network, New Providence, NJ, United States of America - 2Newark Beth Israel Medical Center, Newark, NJ, United States of America - 3Robert Wood Johnson University Hospital, New Brunswick, NJ, United States of America - 4Barnabas Health, Livingston, NJ, United States of America P43 PREVALENCE OF DQA1 AND DPB1 ANTIBODIES AMONG PATIENTS ON THE WAITING LIST FOR KIDNEY TRANSPLANTATION Randi Berg 1, Pernille Koefoed-Nielsen 1 1Aarhus University Hospital, Aarhus N, Denmark P44 ASSESSMENT OF A PORTUGUESE PANEL REACTIVE ANTIBODY CALCULATOR Bruno A. Lima 1, Helena Alves 2 1Oficina de Bioestatística, Vilar Formoso, Portugal -2 Instituto Nacional de Saúde, Porto, Portugal P45 LINKSĒQ™ FOR ABO, A MOLECULAR BASED SUBGROUPING SOLUTION FOR THE ABO BLOOD GROUP William J. Lane 1, Helen Mah 1, Joshua M. Rodriguez 1, Thierry Viard 2, Roland Russnak 2, Vivian Yuen 2, Rania Haddad 2, Isaac Kim 2, Raymond Li 2, Zachary Antovich 2 1Brigham and Women's Hospital, Boston, United States of America - 2Thermo Fisher Scientific, South San Francisco, United States of America P46 CHARACTERIZATION OF POLYMORPHISMS AT THE 3´ UNTRANSLATED REGION OF THE HLA-G GENE IN PATIENTS WITH RENAL GRAFT REJECTION Ana L. Cidral 1, Vanessa Hauer 1, Bruna C. Bertol 2, Eduardo A. Donadi 2, Maria da Graça Bicalho 1 1Federal University of Paraná, Curitiba, Brazil - 2University of São Paulo, Ribeirão Preto, Brazil POSTER
63 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P47 USEFULNESS OF INTRAGRAFT DONOR SPECIFIC ANTIBODY DETECTION IN THE CONTEXT OF ANTIBODY MEDIATED REJECTION WITHOUT CIRCULATING DONOR SPECIFIC ANTIBODIES Anne Parissiadis 1, Jerôme Olagne 2, Philippe Guntz 1, Gabriella Gautier Vargas 2, Nadine Froelich 1, Sophie Caillard 2 1Etablissement Français du Sang-Grand Est, Strasbourg, France - 2Hôpitaux Universitaires, Strasbourg, France P48 DONOR HLA TYPES FROM GRAFT BIOPSIES Mette Christiansen 1, Karen B. Lauridsen 2, Pernille B. Kofoed-Nielsen 1 1Aarhus University Hospital, Aarhus N, Denmark - 2Aalborg University Hospital, Aalborg, Denmark P49 EPITOPE-BASED HLA MATCHING: IN SILICO STRATEGIES TO PREDICT DE NOVO DONOR- SPECIFIC ANTIBODIES IN KIDNEY TRANSPLANTATION Sandra Tafulo 1, Jorge Malheiro 2, Luísa Lobato 2, Leonídio Dias 2, António Castro-Henriques 2 1Portuguese Institute of Blood and Transplantation, Porto, Portugal - 2Hospital de Santo António, Centro Hospitalar do Porto, Porto, Portugal P50 LONG TERM RESULTS OF A DESENSITIZATION PROTOCOL WITH AND WITHOUT RITUXIMAB IN HIGHLY SENSITIZED KIDNEY TRANSPLANT RECIPIENTS Moshe Israeli 1, Heftziba Green 1, Tirza Klein 1, Ruth Rachamimov 1, Sigal Eisner 1, Eviatar Nesher 1, Eytan Mor 1 1Rabin Medical Center, Petach-Tikva, Israel P51 VARIABILITY OF IGG SUBCLASSES OVERTIME David Pinelli 1, Muralidhar T. Gopalakrishnan 1, Anat R. Tambur 1 1Northwestern Univeristy, Chicago, United States of America P52 THE ROLE OF HLA ALLELES IN SUSCEPTIBILITY TO SUSTAINED BK VIREMIA: A SINGLE- CENTER EXPERIENCE Sevim Gönen 1, Özant Helvacı 1, Yaşar Kandur 1, Hakan Sözen 1, Oğuz Söylemezoğlu 1 1Gazi University Faculty of Medicine, Ankara, Turkey P53 A NOVEL TOOL TO DEFINE THE IMMUNOGENICITY OF HUMAN LEUKOCYTE ANTIGEN MISMATCHES Cynthia S.M. Kramer 1, Johan Koster 1, Geert W. Haasnoot 1, Dave L. Roelen 1, Frans H.J. Claas 1, Sebastiaan Heidt 1 1Leiden University Medical Center, Leiden, Netherlands P54 EPLET AND PIRCHE-II ANALYSIS OF ANTIBODY REACTIVITY AFTER FIRST PREGNANCY J. Rene Duquesnoy 1, Marilyn Marrari 1, Matthias Niemann 2, Irene Hösli 3, Stefan Schaub 3, Gideon Hönger 3 1University of Pittsburgh Medical Center, Pittsburgh, United States of America - 2PIRCHE AG, Berlin, Germany - 3University Hospital Basel, Basel, Switzerland P55 MONOSPECIFIC REACTIONS DETECTED BY SINGLE ANTIGENS FAIL TO DETECT NATURAL HLA ANTIGENS Laura Riesco 1, Juan Irure 1, Emilio Rodrigo 1, Marcos López-Hoyos 1, David San Segundo 1 1Marques de Valdecilla Universitary Hospital-IDIVAL, Santander, Spain P56 CLINICAL SIGNIFICANCE OF LUMINEX CROSSMATCH TO DETECT PRE-TRANSPLANT DONOR SPECIFIC ANTIBODIES IN LIVING RELATED RENAL ALLOGRAFT TRANSPLANT: A SINGLE CENTER EXPERIENCE 1 1 1 1 1 1 1 POSTER Monika Jain , Kumar Digvijay , Vinant Bhargava , Anurag Gupta , Manish Malik , Ashwani Gupta , Anil K. Bhalla , Devinder S. Rana 1, I. C. Verma 1 1Sir Ganga Ram Hospital, New Delhi, India
64 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P57 HLA-B*15 SNPS PREDICT THE SEROLOGICALLY DEFINED HLA-B15 SPLIT ANTIGENS Burcu Duygu 1, Benedict M. Matern 1, Christel M.H. Meertens 1, Christina E.M. Voorter 1, Marcel G.J. Tilanus 1 1Maastricht University Medical Center, Maastricht, Netherlands P58 HLA MATCH AND THORACIC TRANSPLANTS Pamela M. Moschini 1, Paola Magistroni 2, Elena Garino 2, Gina A. Mazzola 2, Monica Berrino 2, Silvia Alizzi 2, Tiziana Melchiorre 2, Massimo Boffini2 , Antonio Amoroso 3 1Azienda Ospedaliera Città della Salute e della Scienza, Turin, Italy - 2Città della Salute e della Scienza Hospital, Torino, Italy - 3University of Torino, Torino, Italy P59 PHARMACOGENETIC EFFECTS OF URIDINE DIPHOSPHATE-GLUCURONOSYLTRANSFERASE POLYMORPHISMS ON MYCOPHENOLIC ACID PHARMACOKINETICS IN TURKISH RENAL TRANSPLANT PATIENTS Hayriye Senturk Ciftci 1, Tzevat Tefik2 , Meltem Karadeniz Savran 3, Erol Demir 4, Ismet Nane 2, Fatma Oguz Savran 1, Aydin Turkmen 4 1Istanbul University, Istanbul Faculty of Medicine, Medical Biology Department, Istanbul, Turkey - 2Istanbul University, Istanbul Faculty of Medicine, Department of Urology, Istanbul, Turkey - 3Istanbul University, Istanbul Faculty of Medicine, Department of Anesthesia, Istanbul, Turkey - 4Istanbul University, Istanbul Faculty of Medicine, Department of Nephrology, Istanbul, Turkey P60 DOES CROSSMATCH IMPACT LIVER TRANSPLANTATION OUTCOME? A SINGLE CENTER EXPERIENCE Paola Magistroni 1, Pamela M. Moschini 2, Cristiana Caorsi 1, Francesca E. Bertinetto 1, Ennia Dametto 1, Elena Navaretti 1, Lorenzo Rocchi 1, Francesco Perrone 1, Francesco Tandoi 1, Renato Romagnoli 1, Mauro Salizzoni 1, Antonio Amoroso 3 1Città della Salute e della Scienza Hospital, Torino, Italy - 2Azienda Ospedaliera Città della Salute e della Scienza, Turin, Italy - 3University of Torino, Torino, Italy P61 MONITORING OF HLA-ANTIBODIES IN PATIENTS WHO UNDERWENT HEART TRANSPLANTATION IN THE REPUBLIC OF KAZAKHSTAN Aida Turganbekova 1, Zhandos Burkitbaev 1, Saniya Abdrakhmanova 1, Indira Ramilyeva 1, Dana Baimukasheva 1, Zhazira Saduakas 1, Perizat Zhunus 1 1Republic scientific and production center of transfusiology, Astana, Kazakhstan P62 ANTIENDOTHELIAL CELL AND ANTI AT1R ANTIBODIES IN TWO CLUSTERS OF RENAL TRANSPLANT RECIPIENTS WITH ACUTE ANTIBODY MEDIATED REJECTION - A STUDY FROM A TERTIARY CENTRE IN INDIA Dolly Daniel 1, Santosh Varughese 1, Siddharth Mittal 1 Sam Aruldoss 1, Vinoi G. David 1, Suceena Alexander 1, Anjali Mohapatra 1, John Jude 1 1Christian Medical College, Vellore, India P63 CLINICAL IMPORTANCE OF TYPE 1 ANGIOTENSIN II RECEPTOR (ATR1) Y ANTI-ENDOTELIN-1 TYPE A (ETAR) ANTIBODIES IN KIDNEY TRANSPLANTATION Jaouad El Kaaoui El Band 1, Pedro Martinez-Garcia 1, Gema Martinez-Gonzalez 1, Rafael Alfaro 1, Jose Antonio Galian 1, Francisco Boix 1, Isabel Legaz 2, Maria R. Moya-Quiles 1, Alfredo Minguela 1, Santiago Llorente 1, Manuel Muro 1 1Clinic University Hospital Virgen Arrixaca, Murcia, Spain - 2University of Murcia, Murcia, Spain POSTER
65 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P65 ASSOCIATION BETWEEN RS12917707 SINGLE NUCLEOTIDE POLYMORPHISM AT THE UMOD PROMOTER REGION AND SERUM UROMODULIN LEVELS: IMPLICATIONS IN KIDNEY TRANSPLANTATION Silvia Deaglio 1, Ilaria Notaro 1, Alice Ianniello 2, Daniela F. Giachino 1, Daniela Biongiovanni 2, Pamela M. Moschini 3, Paola Magistroni 2 Giulio Mengozzi 2 Luca Rampoldi 4, Antonio Amoroso 1 1University of Turin, Torino, Italy - 2Azienda Ospedaliera Città della Salute e della Scienza, Torino, Italy - 3Città della Salute e della Scienza Hospital, Torino, Italy - 4San Raffaele Scientific Institute, Milan, Italy P66 HLA ANTIBODY MONITORING AFTER KIDNEY TRANSPLANTATION Tjasa Kovacevic Cuculic 1, Natasa Katalinic 1, Orlic Lidija 1, Helena Kurtovic 1 Marijana Duhovic 1, Ines Simac Susanj 1, Sanja Balen 1 1Clinical Hospital Center, Rijeka, Croatia P67 STARTING THE PAIRED KIDNEY DONATION PROGRAM IN GREECE Angeliki G. Vittoraki 1, Maria Darema 2, Dimitra A. Skoumi 1, Maria D. Apostolaki 1, Ioannis Bokos 2, Alexandra A. Siorenta 1, Georgios Zavvos 2, John N. Boletis 2, Aliki G. Iniotaki 1 1Immunology Department and National Tissue Typing Center, General Hospital of Athens, G.Gennimatas, Athens, Greece - 2Transplantation Unit, Laikon Hospital, Athens, Greece P68 PROGNOSTIC VALUE OF A TEST ALLOWING THE DETECTION OF DONOR SPECIFIC ANTIBODY CAPABLE OF BINDING C3D AT THE TIME OF DIAGNOSIS OF HUMORAL REJECTION IN RENAL TRANSPLANT PATIENTS Marine Gatin 1, Dominique Bertrand 2, Fabienne Farce 1, Françoise Hau 1 1Etablissement Français du Sang Hauts de France Normandie, Bois Guillaume, France - 2CHU de Rouen, Bois Guillaume, France P69 HIGH HLA-DPB1 EXPRESSION IN PRE-IMPLANTATION KIDNEY BIOPSIES IS ASSOCIATED WITH POOR LATE GRAFT FUNCTION Karina L. Mine 1, Tuíla B. Mourão 1, Claudia R. Felipe 2, Gisele F. Rampim 1, José O. Medina-Pestana 2 Hélio Tedesco-Silva 2 Maria Gerbase-DeLima 1 1Immunogenetics Institute, São Paulo, Brazil - 2Hospital do Rim e Hipertensão, São Paulo, Brazil P70 SERUM PRE-TREATMENT WITH FETAL BOVINE SERUM SIGNIFICANTLY INCREASES LUMINEX- BASED HLA ANTIBODY ASSAY SPECIFICITY BY REDUCING HETEROPHILE ANTIBODY INTERFERENCE Andrés Jaramillo 1, Justin L. House 1, Lora J. Nelson 1, Scott Stoll 1, Rose M. Ridgley 1, Hasan A. Khamash 1 1Mayo Clinic, Phoenix, Arizona, United States of America POSTER
66 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
HAEMATOPOIETIC STEM CELL TRANSPLANTATION P71 DISTRIBUTION OF KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTORS (KIRS) ON NK CELLS OF HLA-MATCHED UNRELATED DONOR-RECIPIENT PAIRS RECEIVING HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) Xiaoyan Shan 1, Dongmei Li 1, Wang Dongmei 1, Wang Zhongmei 1 Jing Yuanyuan 1, Wang Jie 1 1 Beijing Red Cross Blood Center, Beijing, China P72 LOSS OF HETEROZYGOSITY RESULTS IN PRE-TRANSPLANT HLA MISTYPING IN ONE PATIENT DIAGNOSED WITH ACUTE MYELOID LEUKEMIA Feiyun Liu 1, Chuen-Ying Lin 1, Chialing Chang 1, Chi-Cheng Li 2, Ya-Chien Yang 1 1National Taiwan University Hospital, Taipei, Taiwan - 2National Taiwan University, Taipei, Taiwan P73 CONTINUOUS MONITORING OF DNA EXTRACTED IN 2013 BY MEANS OF QIASYMPHONY TECHNOLOGY AND KEPT AT +4°C Rayna Ivanova Derin 1, Pascale Loiseau 1, Kahina Amokrane 1, Sophie Caillat Zucman 1 1APHP Hôpital Saint Louis, Paris, France P74 MICRORNA-146A AND NF-KB POLYMORPHISMS AND RISK OF ACUTE GRAFT VERSUS HOST DISEASE POST-ALLOGENEIC STEM CELL TRANSPLANTATION Ghada Mossallam 1, Raafat Abdel Fattah 1, Hossam Kamel 1 1National Cancer Institute, Cairo University, Cairo, Egypt P75 ALLOGENEIC BONE MARROW TRANSPLANTATION IN THREE CASES WITH DOCK 8 DEFICIENCY Turkan Patiroglu 1, Murat Cansever 1, Alper Ozcan 1, Gulsah Uçan1, Sevgi Keles 2, Ekrem Unal 1, Chatila Talal 3, Musa Karakukcu 1 1Erciyes University, Kayseri, Turkey - 2Necmettin Erbakan University, Konya, Turkey - 3Harvard Medical School, Boston,United States of America P76 Y CHROMOSOME DELETION FOUND IN CHIMERISM STR STUDY Laura Perotti 1, Lucia Longa 1, Maristella Prucca 1, Federica Piovano 1, Franco Papola 2, Carla Cervelli 2, Marco Lorenzi 1 1Struttura Complessa Interaziendale Immunoematologia e Medicina Trasfusionale, Cuneo, Italy - 2Centro Regionale di Immunoematologia e Tipizzazione Tissutale, Abruzzo, Italy P77 NULL HLA-A*02:227N ALLELE IN TUMOR CELLS OF THE PATIENT WITH PERIPHERAL T-CELL LYMPHOMA, NOT OTHERWISE SPECIFIED (A CLINICAL CASE) Bella V. Biderman 1, Natalia G. Chernova 1, Igor A. Yakutik 1, Maria V. Nareiko 1, Eugene E. Zvonkov 1, Ekaterina G. Khamaganova 1, Andrey B. Sudarikov 1, Valeriy G. Savchenko 1 1National Research Center for Hematology, Moscow, Russian Federation P78 PCR-SBT CHARACTERIZATION OF A NEW HLA ALLELE: B*14:58 Valentina Cappuzzo 1, Francesco Ingrassia 1, Rosalba Bavetta 1, Serena Mistretta 1, Maria Blando 1, Maria Igea Vega 1, Floriana Bruno 1, Giuseppe Davì1, Raimondo Marcenò1 1Tissue Typing and Immunogenetics Laboratory, Cervello Hospital - Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy P79 NEXT GENERATION SEQUENCING HLA TYPING: FIRST EXPERIENCE IN AN ARGENTINIAN HISTOCOMPATIBILITY LABORATORY 1 1 1
Maria Beatriz. Rodriguez , Ulises Toscanini , Karin Padros POSTER 1PRICAI, Buenos Aires, Argentina
67 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P80 HIGH SIMILARITY HLA TYPING COMBINED WITH CROSS OVER IN A PATIENT WITH SICKLE CELL ANEMIA Osama Al Suraihi 1, Ahmad Bokhari 1, Nabeela Al Baz 1, Ashraf Dada 1 1Pathology & Laboratory Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia P81 THE IMPACT OF KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTORS /HUMAN LEUKOCYTE ANTIGEN CLASS ONE COMBINATIONS ON THE ONE-YEAR PROGNOSIS OF ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN PATIENTS WITH ACUTE LEUKEMIA Shirin Farjadian 1, Marzieh Mansouri 1, Jean Villard 2, Mani Ramzi 1 1Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran - 2Geneva University Hospital, Geneva, Swaziland P82 DETECTING LOSS OF HETEROZYGOSITY IN HLA GENES USING NEXT-GENERATION SEQUENCING IN A PATIENT WITH APLASTIC ANEMIA Viktoria Zakharova 1, Olga Shragina 1, Elena Raykina 1, Zhanna Kuzminova 1, Michael Maschan 1 1Dmitry Rogachev Federal Research Centre of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation P83 AT HEMATOPOIETIC STEM CELL TRANSPLANTATION, THE PERCENTAGE OF COINCIDENCES OF 5 LOCI OF HLA - GENES IN RELATED DONORS: IN SIBLINGS AND IN PARENTS Liudmila Alexandrovna Gracheva 1, Larisa Vladimirovna Petrova 1, Elena Vladimirovna Skorobogatova 1, Ekaterina Andreevna Pristanskova 1, Andrey Anatol'evich Bologov 1 1Russian Children's Clinical Hospital, Moscow, Russian Federation P84 IDENTIFICATION OF NOVEL ALLELES WITH THE USE OF NEXT GENERATION SEQUENCING Olga Shragina 1, Viktoria Zakharova 1, Elena Raykina 1, Michael Maschan 1, Alexei Maschan 1 1Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation P85 HIGH-FIDELITY HLA GENOTYPING IN THE POLISH POPULATION WITH THE USE OF NEXT GENERATION SEQUENCING Anna Bogacz 1, Michał Góralski 1, Alicja Bukowska 1, Mateusz Sowiński 1, Karol Jopek 1, Mariusz Gronkowski 1, Sylwia Wróblewska-Kabba 1, Michał Kolasiński 1, Hanna Skalisz 1, Krzysztof Olbromski 1 1Regional Blood Center in Poznan, Poznan, Poland P86 ANTI-HLA AND DONOR SPECIFIC ANTI-HLA (DSA) IN ALLOGENEIC HAEMATOPOIETIC STEM CELL TRANSPLANTATION (3 YEARS EXPERIENCE) Maria Dolores De Juan 1, Larraitz Aragon 1, Nerea Olivares 2, David Monzón 1, Jose Javier Ferreiro 1, Aitziber Alkorta 1 1Donostia University Hospital, Donostia-San Sebastian, Spain - 2Cruces University Hospital, Bilbao, Spain P87 DETECTION OF A NOVEL ALLELE WITH NGS HAS NEVER BEEN EASIER Vera Siffnerova 1, Milena Vrana 1, Libor Kolesar 2, Efi Melista3 1The Institute of Haematology and Blood Transfusion, Prague, Czech Republic - 2Omixon Biocomputing Kft., Budapest, Hungary - 3Omixon Inc., United States of America P88 CORD BLOOD UNITS RELEASE ACTIVITY OF PADOVA CORD BLOOD BANK: SYNERGY BETWEEN CORD BLOOD BANK AND HLA LABORATORY Maria Paola Albergoni 1, Daniela Bovo 2, Aurora Strano 2, Roberta Favero 1, Genny Franceschetto 2, Giustina De Silvestro 1, Roberta Destro 2 1 2 POSTER UOC Immunotrasfusionale - DIMT Padova - Azienda Ospedaliera di Padova, Padova, Italy - Oncoematologia Pediatrica - Padova Cord Blood Bank - Azienda Ospedaliera di Padova, Padova, Italy
68 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P89 COMPARISON OF UNRELATED DONOR SEARCH TIMES VIA THE NATIONAL DONOR REGISTRY AND INTERNATIONAL DONOR REGISTRIES: A SINGLE CENTER TWO YEARS EXPERIENCE FROM TURKEY Emel Gucyener 1, Fatma Savran Oguz 2, Zafer Gulbas 1, Kader Caliskan 1, Esra Isildak 1, Leman Ozel 1, Medine Hasauhadar 3 1Anadolu Medical Centre, Kocaeli, Turkey - 2Istanbul University, Istanbul Faculty of Medicine, Medical Biology Department, Istanbul, Turkey - 3Stem Cell Coordination Center of Turkey, Ankara, Turkey P90 ASSESSMENT OF THE PURITY OF ISOLATED CD3+ T CELL POPULATIONS BY A NEW MOLECULAR BIOLOGY TECHNOLOGY: IMPACT ON THE QUANTIFICATION OF CHIMERISM MONITORING POST HAEMATOPOITIC STEM CELL TRANSPLANTATION Aurélie Lopasso 1, Clémence Demerle 1, Mélanie Velier 1, Sarah Dassa 1, Noura Kouba 1, Virginia Ferreira 1, Nicolino Brunet 2, Sophie Simon 1, Agnes Basire 1, Christophe Picard 3 1EFS PACAC, Marseille, France - 2AP-HM, Marseille, France - 3UMR7268 AMU CNRS EFS, MARSEILLE, France P91 HLA-G 14BP DELETION EFFECT ON STEM CELL TRANSPLANTATION Sally Elfishawi1 , Raafat Abdel Fattah 1 1National Cancer Institute, Cairo University, Cairo, Egypt P92 DOCUMENTATION OF RARE HLA ALLELES Pedro Cano 1, Jennifer Wendel 1, Crystal Iozzino 1, Rachel Boasi 1, Yasmill Ramirez 1, Kathy Blaney 1 1Moffitt Cancer Center, Tampa, United States of America P93 THE OPTIMAL DONOR PROFILE IN THE ERA OF NEXT GENERATION SEQUENCING? Vinzenz Lange 1, Gerhard Schöfl1 , Monika Füssel 1, Johannes Schetelig 2, Alexander H. Schmidt 3 1DKMS Life Science Lab, Dresden, Germany - 2Technische Universität Dresden, Dresden, Germany - 3DKMS, Tübingen, Germany P94 MANAGEMENT OF DSA IN HAEMATOLOGICAL STEM CELL TRANSPLANTATION Valeria Miotti 1, Donatella Londero 1, Vincenzo De Angelis 1 1ASUIUD, Udine, Italy P95 DYNAMIC TRENDS IN SEARCHING FOR MATCHED UNRELATED DONORS IN ISRAEL: A CURRENT UPDATE (2013-2017) Chen-li Levi 1, Moshe Yeshurun 1, Jerry Stein 2, Tirza Klein 1, Anat Yahel 2, Michal Sela-Navon 1, Liat Shargian 1, Oren Pasvoski 1, Moshe Israeli 1 1Rabin Medical Center, Petach-Tikva, Israel - 2Schneider Children’s Medical Center, Petach-Tikva, Israel P96 THE QUANTITATIVE PCR METHOD AS METHOD OF CHOICE IN CHIMERISM MONITORING AFTER HSCT Katarina Stingl Jankovic 1, Marija Maskalan 1, Zorana Grubic 1, Marija Burek Kamenaric 1, Renata Zunec 1 1University Hospital Centre Zagreb, Zagreb, Croatia P97 STRUCTURAL EPITOPE (EPLET)-BASED ANALYSIS OF HLA-ALLOIMMUNIZED PLATELET TRANSFUSION Qiang Chen 1, Mengdan Li 2, Jue Wang 3 1Institute of Blood Transfusion, Chinese Academy of Medical Sciences And Sichuan Cord Blood Bank, Chengdu, China - 2Sichuan Cord Blood Blank, Chengdu, China - 3Institute of blood transfusion, Chinese Academy of Medical Sciences, Chengdu, China POSTER
69 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P98 ROLE OF KIR RECEPTOR-HLA LIGAND MATCH/MISMATCH ON OUTCOMES IN POST TRANSPLANT CYCLOPHOSPHAMIDE BASED HAPLOIDENTICAL TRANSPLANTATION Meenakshi Singh 1, Selma D. Silva 1, Sachin Punatar 2, Anant Gokarn 2, Avinash Bonda 2, Libin Mathew 2, Manisha Tambe 1, Sadhana Kannan 2, Sunil Rajadhyaksha 1, Navin Khattry 2 1Tata Memorial Hospital, Mumbai, India - 2Tata Memorial Centre, Mumbai, India P99 FULL LENGTH NEXT GENERATION SEQUENCING (NGS) TYPING OF HLA-DPB1 ALLELES COMPRISES THE DETECTION OF ALLELE SPECIFIC FUNCTIONAL, CLINICALLY SIGNIFICANT SINGLE NUCLEOTIDE POLYMORPHISMS Ingrid Faé1, Peter Kalhs 1, Sabine Wenda 1, Gottfried F. Fischer 1 1Medical University Vienna, Vienna, Austria P100 DEVELOPMENT OF PERSISTENT MIXED CHIMERISM (MC) IN ALLO-HSCT TRANSPLANTED BETA-THAL PATIENTS IS ASSOCIATED WITH LOW MC EARLY AFTER TRANSPLANT AND TR1 CELLS Silvia Gregori 1, Tiziana Galluccio 2, Maria Grazia Roncarolo 3, Rosa Bacchetta 3, Marco Andreani 2 1San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, Italy - 2IME Foundation at Polyclinic of Tor Vergata, Rome, Italy - 3Stanford School of Medicine, Stanford, United States of America P101 IN SILICO PREDICTION OF NON-PERMISSIVE HLA-DPB1 MISMATCHES IN UNRELATED HCT BY FUNCTIONAL DISTANCE Pietro Crivello 1, Esteban Arrieta-Bolaños 1, Bronwen E. Shaw 2, Kwang Woo Ahn 2, Hai-Lin Wang 2, Michael R. Verneris 3, Katharine Hsu 4, Joseph Pidala 5, Stephanie J. Lee 6, Katharina Fleischhauer 1, Stephen Spellman 7 1Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany - 2Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, United States of America - 3Pediatric BMT, University of Colorado, Aurora, United States of America - 4Memorial Sloan Kettering Cancer Center, New York, United States of America - 5Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, Tampa, United States of America - 6Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, United States of America - 7Center for International Blood and Marrow Transplant Research, National Marrow Donor Program/Be the Match, Minneapolis, United States of America P102 AN IMPROVED SEARCH ALGORITHM BY HLA-DPB1 T CELL EPITOPE MATCHING Sendi Montanič 1, Sabina Kunilo Jamnik 1, Blanka Vidan-Jeras 1 1Blood Transfusion Center of Slovenia, Ljubljana, Slovenia P103 HLA PHASED HAPLOTYPES IN SWITZERLAND, PREDICTIVE VALUE FOR MATCHED UNRELATED DONOR SEARCHES AND CLINICAL OUTCOME AFTER HSCT Stéphane Buhler 1, Helen Baldomero 2, Sylvie Ferrari-Lacraz 1, José M. Nunes 3, Alicia Sanchez-Mazas 3, Stravoula Massouridi-Levrat 1, Dominik Heim 2, Joerg Halter 2, Gayathri Nair 4, Yves Chalandon 1, Urs Schanz 4, Tayfun Guengoer 5, Grazia Nicoloso 6, Jean-Marie Tiercy 1, Jakob Passweg 2, Jean Villard 1 1Geneva University Hospitals, Geneva, Switzerland - 2Basel University Hospital, Basel, Switzerland - 3University of Geneva, Geneva, Switzerland - 4University Hospital of Zürich, Zürich, Switzerland - 5Childrens Hospital, Zürich, Switzerland - 6Foundation Swiss Blood Stem Cells, Bern, Switzerland P104 EASYMATCH-R: THE VALIDATION OF A WEB APPLICATION FOR DONOR QUERY IN HAEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) Alexandre Walencik 1, Estelle Geffard 2, Sophie Limou 3, Anne Cesbron 1, Nicolas Vince2, Pierre-Antoine Gourraud 2 1EFS Centre-Pays de la Loire, Nantes, France - 2INSERM, Université de Nantes, Nantes, France - 3INSERM, Ecole Centrale de POSTER Nantes, Nantes, France
70 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P105 HAPLOIDENTICAL HAEMATOPOIETIC STEM CELL TRANSPLANTATION AND HLA- ANTIBODIES: ABOUT A CLINICAL CASE OF APPARITION OF SPECIFIC RECIPIENT ANTIBODIES DURING POST STEM CELL TRANSPLANTATION PERIOD Anne Parissiadis 1, Philippe Guntz 1, Marie-Pierre Ledoux 2, Bruno Lioure 2 1Etablissement Français du Sang-Grand Est, Strasbourg, France - 2Hôpitaux Universitaires, Strasbourg, France P106 INCIDENCE OF ANTI-HLA ANTIBODIES IN PAEDIATRIC PATIENTS AFFECTED BY HAEMATOLOGICAL DISEASES AND CANDIDATE TO HAEMATOPOIETIC STEM CELL TRANSPLANT P. Giustiniani 1, C. Parlavecchio 1, P. Merli 1, F. Galaverna 1, R. M. Pinto 1, S. Bordasco 1, M. Montanari 1, F. Locatelli 1 1Bambino Gesù Children’s Hospital, Rome, Italy P107 REVEALING THE HIDDEN CHIMERISM BY STR GENOTYPING OF LEUKOCYTE SUBSETS Gabriela Berardi 1, Cintia Llull 1, Nicolas Fernandez Escobar 2, Gregorio Jaimovich 2, Maria Beatriz Rodriguez 1, Pablo Morikone 1, Karin Padros 1, Ulises Toscanini 1 1PRICAI, Buenos Aires, Argentina - 2CEHT, Buenos Aires, Argentina P108 THE IMPACT OF DONOR NATURAL KILLER CELL RECEPTOR GENES ON OUTCOME OF ALLOGENEIC HAEMATOPOIETIC STEM CELL TRANSPLANTATION FROM HLA-IDENTICAL SIBLING IN PATIENTS WITH ACUTE MYELOID LEUKEMIA Ekaterina G. Khamaganova 1, Elena N. Parovichnikova 1, Larisa A. Kuzmina 1, Elena P. Kuzminova 1, Sergey M. Kulikov 1, Valeriy G. Savchenko 1 1National Research Center for Hematology, Moscow, Russian Federation P109 OVERVIEW OF POST-TRANSPLANT MONITORING IN PATIENTS AFTER HAPLOIDENTICAL ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION Hana Cechova 1, Kristyna Pegova 1, Lucie Pavlatova 1, Radka Zizkova 1, Pavla Hrabakova 1, Renata Prerovska 1, Martina Stankova 1, Dagmar Brezinova 1 1Institut of Hematology and Blood Transfusion, Prague, Czech Republic P110 IMPACT OF ANTI-HLA ANTIBODIES ON EARLY COMPLICATIONS AND OUTCOME AFTER UNRELATED HAEMATOPOIETIC STEM CELL TRANSPLANTATION Arturas Jakubauskas 1, Rita Cekauskiene 1, Beatrice Valatkaite-Rakstiene 1, Laimonas Griskevicius 2 1State Research Institute Center for Innovative Medicine & Vilnius University Hospital, Vilnius, Lithuania - 2Clinics of Internal, Family Medicine and Oncology, Faculty of Medicine, Vilnius University, & Vilnius University Hospital, Vilnius, Lithuania P111 ANALYSIS OF THE KIR GENES IMPACT ON HEMATOPOIETIC STEM CELL TRANSPLANTATION OUTCOME ACCORDING TO THREE DIFFERENT PREDICTIVE MODELS FROM LITERATURE Marija Kamenaric Burek 1, Katarina Stingl Jankovic 1, Zorana Grubic 1, Marija Maskalan 1, Ranka Serventi Seiwerth 1, Mirta Mikulic 1, Renata Zunec 1 1University Hospital Centre Zagreb, Zagreb, Croatia P112 IMPACT OF NEXT-GENERATION SEQUENCING IN THE TYPING OF DONORS IN BULGARIAN BONE MARROW DONOR REGISTRY Tsvetelin Lukanov 1, Lyudmila Quin 1, Antoaneta Nedyalkova 1, Bushra Al Hadra 2, Milena Ivanova 2, Elissaveta Naumova 2 1University Hospital Alexandrovska, Sofia, Bulgaria -2 Medical University Sofia, University Hospital Alexandrovska, Sofia, Bulgaria POSTER
71 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P113 AN AUDIT OF THE VOLUNTEER UNRELATED DONOR SEARCH PROCESS IN SUPPORT OF ALLOGENEIC HSCT OVER A 5 YEAR PERIOD Deborah A. Sage 1, Shahram Hemmatpour1, Debbie Richardson 2, Kim Orchard 2 1NHS Blood and Transplant, Tooting, London, United Kingdom (Great Britain) - 2Southampton University Hospital, Southampton, United Kingdom (Great Britain) P114 ANTI-HLA-DP ANTIBODIES Pedro Cano 1, Jennifer Wendel 1, Crystal Iozzino 1, Rachel Boasi 1, Yasmill Ramirez 1, Kathy Blaney 1 1Moffitt Cancer Center, Tampa, United States of America P115 LOSS OF HETEROZYGOSITY IN THE HLA REGION AND SENSITIVITY OF HLA TYPING METHODS FOR DETECTING UNDER-REPRESENTED ALLELES Eszter Lazar-Molnar 1, Lori Ellinger 2, Kevin Williams 2, Ann Poles 2, Erica Andersen 1, Tracie Profaizer 3, Jamie L. Duke 4, Deborah Ferriola 4, Julio Delgado 1, Dimitri Monos 4 1University of Utah School of Medicine, Salt Lake City, United States of America - 2Histocompatibility and Immunogenetics Laboratory, University of Utah Health, Salt Lake City, United States of America - 3ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, United States of America - 4The Children’s Hospital of Philadelphia, Philadelphia, United States of America
IMMUNOTHERAPY, GENE THERAPY & CELLULAR THERAPY P116 MODIFICATION OF CD8+ T CELLS WITH T CELL RECEPTOR SPECIFIC FOR MINOR ANTIGEN ACC-1Y Artem M. Pilunov 1, Anna A. Kuchmiy 1, Savely A. Sheetikov 1, Nadezhda A. Bykova 1, Sergey Y. Filkin 1, Dmitry S. Romaniuk 1, Grigory A. Efimov 1 1National Research Center for Hematology, Moscow, Russian Federation P117 EXPRESSION OF THE HUMAN LEUKOCYTE ANTIGEN G MOLECULE IN ERYTHROID PRECURSORS FROM AN IN VITRO CULTURE MODEL OF HUMAN CORD BLOOD CD34+ ERYTHROID PROGENITORS Aurélie Lopasso 1, Monique Silvy 2, Julie Di Cristofaro 2, Pascal Bailly 2, Christophe Picard 2 1EFS PACAC, Marseille, France - 2UMR7268 AMU CNRS EFS, Marseille, France
BIOINFORMATICS P118 A PRECISION MEDICINE APPLICATION: PERSONALIZED CONTEXTUALIZATION OF PATIENTS AFTER SOLID ORGAN TRANSPLANTATION Estelle Geffard 1, Pauline Scherdel 1, Sophie Limou 1, Sophie Brouard 1, Adrien Tissot 1 Colt investigators 1, Divat Investigators 1, Antoine Magnan1, Magali Giral 1, Gilles Blancho 1, Nicolas Vince 1, Pierre-Antoine Gourraud 1 1INSERM, Université de Nantes, Nantes, France P119 APPLICATION OF EASY-HLA TO 2,260 SOLID ORGAN TRANSPLANT DONOR-RECIPIENT PAIRS FROM 2 COHORTS: STATISTICALLY UPGRADED HLA TYPING FOR RESEARCH USE Estelle Geffard 1, Alexandre Walencik 2, Sophie Limou 1, Pauline Scherdel 1, Adrien Tissot 1, Divat investigators 1, Colt investigators 1, Gilles Blancho 1, Magali Giral 1, Antoine Magnan1, Anne Cesbron 2, Nicolas Vince 1, 1
POSTER Pierre-Antoine Gourraud 1INSERM, Université de Nantes, Nantes, France - 2EFS Centre - Pays de la Loire, Nantes, France
72 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P120 INTRODUCING ONLINE TOOLS TO FACILITATE HLA-RELATED RESEARCH Ö. Orkun Sürel 1, Ömer Korkmaz 2, Jacob L. McCauley 3, Mehmet Tevfik Dorak 4, Mustafa Dogan 5 1EPROM Electronic Project & Microwave Ind. Ltd. Co., Ankara, Turkey - 2Ankara University, Ankara, Turkey - 3University of Miami, John P. Hussman Institute for Human Genomics, Miami, FL, United States of America - 4Kingston University London, Kingston, United Kingdom (Great Britain) - 5Istanbul Technical University, Istanbul, Turkey P121 TYPELOADER FOR WINDOWS: AUTOMATED SUBMISSION OF NOVEL ALLELES IN FULL LENGTH Bianca Schöne 1, Markus Fuhrmann 1, Vineeth Surendranath 1, Julia Phieler 1, Alexander H. Schmidt 2, Gerhard Schöfl1 , Vinzenz Lange 1 1DKMS Life Science Lab, Dresden, Germany - 2DKMS, Tübingen, Germany P122 SNP-HLA REFERENCE CONSORTIUM: HLA AND SNP DATA SHARING FOR PROMOTING HLA- CENTRIC ANALYSES IN GENOMICS Nicolas Vince 1, Venceslas Douillard 1, Estelle Geffard 1, Sophie Limou 1, Pierre-Antoine Gourraud 1 1INSERM, Université de Nantes, Nantes, France
NEW TECHNOLOGIES P123 FULL LENGTH CLASS I GENE SEQUENCING TO PREDICT THE CLASS I PROTEIN SEQUENCES AND RULE OUT NULL ALLELES OR ALTERED PROTEIN EXPRESSIONS Nezih Cereb 1, Eunsil Kim 1, Vijayaragavan Seshadri 1, Sungkyu Kim 1, Soo Young Yang1 1HistoGenetics, Ossining, New York, United States of America P124 PERFORMANCE CHARACTERISTICS OF AN NGS-BASED HLA TYPING METHOD Manuela Testi 1, Manuela Catalano 1, Alessandra Moscetti 1, Lorenza Fenici 1, Lara Florean 1, Maria Rita Gallone 1, Paola Grammatico 1 1Medical Genetics Lab, Sapienza University, San Camillo-Forlanini Hospital, Rome, Italy P125 VALIDATION OF NGS HLA TYPING BEFORE ITS INTRODUCTION IN THE LABORATORY ROUTINE ACTIVITY Marco Andreani 1, Manuela Testi 2, Rossella Condello 1, Giuseppe Testa 1, Mariarosa Battarra 1 1Laboratory of Immunogenetics and Transplant Biology - IME Foundation at Polyclinic of Tor Vergata, Rome, Italy - 2San Camillo-Forlanini Hospital, Rome, Italy P126 HLA HAPLOTYPES IN A GREEK POPULATION BY NGS TECHNOLOGY Katerina Tarassi 1, Amanda Willis 2, Vasiliki Kitsiou 1, Kazutoyo Osoegawa 3, Diamanto Kouniaki 1, Theofilos Athanassiades1 , Marcelo Fernández-Viña3, Medhat Askar 2, Alexandra Tsirogianni 1 1Evangelismos Hospital, Athens, Greece - 2Baylor University Medical Center, Dallas, United States of America - 3Stanford Medical School Blood Center, Palo Alto, United States of America P127 HLA-B*27 TYPING WITH A TRIPLEX REAL TIME PCR IN A ROUTINE LABORATORY Alice P. Pedersen 1, Menaka Andersen 1, Tore Jensen 1, Marte K. Viken 1 1Department of Immunology, Oslo, Norway P128 EVALUATION OF THE NXTYPE KIT FOR HLA-TYPING WITH THE S5 IONTORRENT PLATFORM Marine Cargou 1, Charlene Bouthemy 1, Mamy Ralazamahaleo 1, Gwendaline Guidicelli 1, Jonathan Visentin 1 1 Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France POSTER
73 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P129 AUTOMATION OF THE NGSGO LIBRARY PREPARATION WORKFLOW FOR HLA TYPING ON THE BIOMEK 4000 WORKSTATION Bram Luiken 1, Debby G.M. Krom 2, Gayatri C. Tetar 2, Elena Tavkin 3, Shilpa Parakh 4, Joseph Lu 4, Alisa Jackson 4, Maarten T. Penning 1, Wendy T. Swelsen 2, Neubury M. Lardy 2, Sake van Wageningen 1 1GenDx, Utrecht, Netherlands - 2Sanquin, Amsterdam, Netherlands - 3Beckman Coulter, Krefeld, Germany - 4Beckman Coulter, Indianapolis, United States of America P130 STREAMLINING NGS HLA DATA ANALYSES USING NGSIGNITION AND NGSSERVER Raul Kooter 1, Job Geerligs 1, Frans-Paul Ruzius 1, Pieter Meulenberg 1, Joris Albers 1, Maarten T. Penning 1, Hanneke W.M. van Deutekom 1, Erik H. Rozemuller 1 1GenDx, Utrecht, Netherlands P131 EVALUATION OF THREE LABORATORY METHODS FOR DETECTING PREFORMED HUMAN LEUKOCYTE ANTIGEN ANTIBODIES Luyanda Laura Kwofie1 , Pieter W. Meyer 1 1University of Pretoria, Pretoria, South Africa P132 HIGH RESOLUTION HLA TYPING STRATEGIES: A SINGLE CENTER’S EXPERIENCE Francesco Ingrassia 1, Valentina Cappuzzo 1, Maria Igea Vega 1, Maria Blando 1, Rosalba Bavetta 1, Serena Mistretta 1, Floriana Bruno 1, Raimondo Marcenò 1 1Laboratorio di Tipizzazione Tessutale ed Immunologia dei Trapianti, Medicina Trasfusionale e dei Trapianti, Palermo, Italy P133 AN AUTOMATED WORKFLOW FOR HLA TYPING USING GenDx NGSGO ON THE TECAN FREEDOM EVO NGS WORKSTATION Reinhard Kelsch 1, Hanne Grawe 1, Bram Luiken 2, Daniel Mathow 2, Sake van Wageningen 2, Malte Heyer 3, Benjamin Vogel 3, Rafael Alvarez 3, Sirak Kifle3 1Institute of Transfusion Medicine and Transplantation Immunology, Münster, Germany - 2GenDx, Utrecht, Netherlands - 3Tecan, Männedorf, Switzerland P134 DEVELOPMENT OF FULL-GENE HLA-DPB1 NGS TYPING ON THE MISEQ AND ION S5 PLATFORMS Winnie Chong 1, Sandra G. Guerra 1, Siobhan Hamilton-Jones 1, Colin J. Brown 1, Cristina V. Navarrete 1 1NHS Blood and Transplant, London, United Kingdom (Great Britain) P135 FROM THE SAMPLE TO DONOR/RECIPIENT COMPATIBILITY: A COMPREHENSIVE RANGE OF LABORATORY REAGENTS AND EQUIPMENT FOR NGS-BASED GENOTYPING OF CLASSICAL AND NON-CLASSICAL HLA GENES Mehdi Alizadeh 1, Christophe Picard 2, Alexandre Walencik 3, Eric Perrot 4, Florence Bennasar 1, Sterenn Fraboulet 1, Franck Verite 1, Gilbert Semana 1 1Etablissement Français du Sang ETS-Bretagne, Rennes, France - 2Etablissement Français du Sang PACA-Corse, Marseille, France - 3Etablissement Français du Sang Pays de la Loire, Nantes, France - 4Etablissement Français du Sang, La Plaine Saint -Denis, France P136 DEFINING 11 HLA LOCI IN A DIVERSE CORD BLOOD BANK USING THE ION S5 Sandra G. Guerra 1, Siobhan Hamilton-Jones 1, Colin J. Brown 1, Cristina V. Navarrete 1, Winnie Chong 1 1NHS Blood and Transplant, London, United Kingdom (Great Britain) POSTER
74 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P137 A LONG-RANGE WHOLE-GENE AMPLIFICATION APPROACH FOR THE CHARACTERIZATION OF NOVEL KIR ALLELES Marie Günther 1, Kathrin Lang 1, Kuntal Worah 1, Steffen Klasberg 1, Gerhard Schöfl1 , Alexander H. Schmidt 2, André P. Mäurer 1, Vinzenz Lange 1 1DKMS Life Science Lab, Dresden, Germany - 2DKMS, Tübingen, Germany P138 ANALYSIS OF CLASS II GENES (DRB1, DQB1, AND DPB1): IN-PHASE LONG RANGE SEQUENCING DATA PRODUCED BY USING 3RD GENERATION SEQUENCING PACBIO SMRT TECHNOLOGY Nezih Cereb 1, Eunsil Kim 1, Jaejun Ryu 1, Vijayaragavan Seshadri 1, Sungkyu Kim 1, Soo Young Yang 1 1HistoGenetics, Ossining, New York, United States of America P139 A NEXT GENERATION SEQUENCING BASED GENOTYPING STRATEGY FOR MICA AND MICB Jens Pruschke 1, Daniel Schefzyk 1, Kathrin Lang 2, Bianca Schoene 2, Christine Gnahm 1, Vinzenz Lange 2, Alexander H. Schmidt 1, Jan Hofmann 1, Jürgen Sauter 1 1DKMS, Tübingen, Germany - 2DKMS Life Science Lab, Dresden, Germany P140 HLA TYPING TO THE 3RD AND 4TH FIELD RESOLUTION: RESULTS FROM THE UK NEQAS FOR H&I PILOT EXTERNAL QUALITY ASSESSMENT SCHEME Deborah L. Pritchard 1, M T. Rees 1 1Welsh Transplantation and Immunogenetics Laboratory, Pontyclun, United Kingdom (Great Britain) P141 NGS-BASED KIR TYPING AT HIGH RESOLUTION: CHALLENGES AND SOLUTIONS FOR THE KIR FRAMEWORK GENES Loes A.L. van de Pasch 1, Sanne Vendelbosch 1, Karin van Ham 1, Hanneke W.M. van Deutekom 1, Maarten T. Penning 1, Erik H. Rozemuller 1 1GenDx, Utrecht, Netherlands P142 HAPLOTYPE RESOLUTION OF MHC IN CATTLE THROUGH TARGETED ENRICHMENT AND SMRT SEQUENCING Dorothea Harrison 1, John C. Schwartz 1, Derek M. Bickhart 2, Tim P L. Smith 3, John A. Hammond 1 1The Pirbright Institute, Woking, United Kingdom (Great Britain) - 2Cell Wall Biology and Utilization Research, Madison, United States of America - 3Meat Animal Research Center, Clay Center, United States of America P143 MAPPING THE STRENGTHS AND WEAKNESSES OF AN HLA NEXT GENERATION SEQUENCING WORKFLOW Vicky Van Sandt 1, Aleksandar Senev 1, Johan Kerkhofs 1, Ming Li 2, Tommy Liu 2, Heylen Christine 3, Marie-Paule Emonds 1 1Belgian Red Cross-Flanders, Mechelen, Belgium - 2Immucor, 1916 Old Middlefield Way, Mountain View, CA 94043, United States of America - 3Immucor Transplant Diagnostics, Nijlen, Belgium P144 BENEFITS OF AN AUTOMATED NEXT GENERATION SEQUENCING PROTOCOL FOR HLA TYPING Sue Davey 1, Dimitra Niokou 1, Zareen Deplano 1, Monica Kyriacou 1, Trevor Green 1, Vasnti Jesani-Hethcoat 1, Thusa Sathananthan 1, Colin Brown 1 1NHS Blood and Transplant, London, United Kingdom (Great Britain) P145 A NOVEL NGS-BASED HIGH-RESOLUTION GENOTYPING STRATEGY FOR HLA-E Loes A.L. van de Pasch 1, Michelle van Heck 1, Remco Malestein 1, Maarten T. Penning 1, Erik H. Rozemuller 1 1 GenDx, Utrecht, Netherlands POSTER
75 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P146 DEFINITIVE RESOLUTION OF HLA TYPING ERRORS AND AMBIGUITIES BY NGS TYPING Amalia Dinou1, Maria Spyropoulou-Vlachou 2, Vasiliki Vrani 3, Efstathios Michalopoulos1, Catherine Stavropoulos-Giokas1 1Hellenic Cord Blood Bank-Biomedical Research Foundation Of the Academy of Athens, Athens, Greece - 2Alexandra General Hospital of Athens, Athens, Greece - 3General Hospital of Athens ‘’G.Gennimatas’’, Athens, Greece P147 CONQUERING THE EFI NGS STANDARDS WITH HOLOTYPE AND TWIN Libor Kolesar 1, Efi Melista2 , Nora Nagy 1, Dorrotya Berki 3, Peter Meintjes 2 1Omixon Biocomputing Ltd., Budapest, Hungary - 2Omixon Inc., Cambridge, United States of America - 3Omixon Biocomputing Kft., Budapest, Hungary
MHC EVOLUTION, ANTHROPOLOGY & POPULATION GENETICS P148 HLA GENES IN BARRANQUILLA (NORTH COLOMBIA): SEARCHING FOR CRYPTIC AMERINDIAN GENES Antonio Arnaiz Villena 1, Brayan Bayona 2, Jose Palacio-Gruber 1, Ennio Hernandez 2, Ester Muñiz 1, Cristina Campos 1, Ignacio Juarez 1, Eduardo Gomez-Casado 1, José Manuel Martín-Villa 1, Carlos Silvera 2 1University Complutense,The Madrid Regional Blood Center (Centro de Transfusion), Madrid, Spain - 2Immunogenetics, Universidad del Norte., Barranquilla, Colombia P149 FREQUENCIES OF HLA GENES AND FIVE-LOCUS HAPLOTYPES OF THE OSSETIANS IN NORTH CAUCASUS Elena P. Kuzminova 1, Ekaterina G. Khamaganova 1, Regina S. Chapova 1 1National Research Center for Hematology, Moscow, Russian Federation P150 THE ASSOCIATION OF GENOTYPES HLA-DQ2 AND HLA-DQ8 WITH CELIAC DISEASE (CD) IN PEDIATRIC PATIENTS OF SLOVAK POPULATION Sona Penickova 1, Vladimir Bosak 2 1BAG Health Care GmbH, Praha 8, Czech Republic - 2Trnava University, Trnava, Slovakia P151 NEONATAL LYMPHOPENIA SCREENING FOR DIAGNOSIS OF COMBINED IMMUNODEFICIENCY: A SINGLE CENTER STUDY Turkan Patiroglu 1, Murat Cansever 1, Aykut Poyraz 1 1Erciyes University, Kayseri, Turkey P152 THE MOST FREQUENT HLA ALLELES AND HAPLOTYPES IN RUSSIAN POPULATIONS OF SAMARA AND CHELYABINSK REGIONS Dmitry Y. Klyuchnikov1, Mikhail N. Vavilov 2, Larisa M. Trusova1, Tatiana A. Suslova2, Olga V. Tyumina1 1The Clinical Centre of Cell Technologies, Samara, Russian Federation - 2Chelyabinsk State University, Chelyabinsk, Russian Federation P153 ASSOCIATION OF HLA CLASS I AND II ALLELES WITH SUSCEPTIBILITY TO SEVERE ACUTE RESPIRATORY SYNDROME INFECTION IN NORTH CHINA Dongmei Li 1, Yan Qiu 1, Tao Wu 2, Dongjing Liu 2, Yi Zhang 1, Wei Li1 1Beijing Red Cross Blood Center, Beijing, China - 2School of Public Health, Peking University, Beijing, China P154 CHARACTERIZATION OF A NOVEL HLA-DRB1*12 ALLELE, HLA-DRB1*12:57 Qiang Chen 1, Xingjie Li 2, Hai Zou 2, Mengdan Li 2
POSTER 1Institute of Blood Transfusion, Chinese Academy of Medical Sciences And Sichuan Cord Blood Bank, Chengdu, China - 2Sichuan Cord Blood Blank, Chengdu, China
76 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P155 HIGH-RESOLUTION CHARACTERIZATION OF ALLELIC AND HAPLOTYPIC HLA FREQUENCIES DISTRIBUTION IN A SPANISH POPULATION USING HIGH-THROUGHPUT NEXT-GENERATION SEQUENCING Gonzalo Montero-Martin 1, Lisa E. Creary 1, Kalyan Mallempati 2, Sridevi Gangavarapu 2, Tamara Vayntrub 2, Dolores Planelles 3, Carlos Vilches 4, Jose Luis Caro 5, Maria Jose Herrero-Mata 5, Francisco Sanchez-Gordo 6, Maria Francisca González-Escribano 7, Manuel Muro 8, Maria R. Moya-Quiles 8, Rafael Gonzalez-Fernandez 9, Florentino Sanchez-Garcia 10, J. Gonzalo Ocejo-Vinyals 11, Antonio Balas 12, Jose Luis Vicario 12, Luis Marin 13, Marcelo A. Fernández-Viña 1 1Stanford University School of Medicine, Department of Pathology, Palo Alto, United States of America - 2Stanford Blood Center, Palo Alto, United States of America - 3Centro de Transfusiones de Valencia, Valencia, Spain - 4H. U. Puerta de Hierro, Madrid, Spain - 5Banc de Sang y Teixits, Barcelona, Spain - 6Centro de Transfusión de Málaga, Malaga, Spain - 7H. U. Virgen del Rocío, Sevilla, Spain - 8H. U. Virgen de la Arrixaca, Murcia, Spain - 9Hospital Universitario Reina Sofía, Cordoba, Spain - 10Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Spain - 11Hospital Universitario Marqués de Valdecilla, Santander, Spain - 12Centro de Transfusión de la Comunidad de Madrid, Madrid, Spain - 13University Hospital of Salamanca (IBSAL), Salamanca, Spain P156 HLA DP ALLELES AND HLA-A, -B, -C, -DRB1, -DQB1, -DPB1 HAPLOTYPES BASED ON A FAMILY STUDY IN NORTH GREECE Anna Boukla 1, Asimina Fylaktou 1, Theodoros Karampatakis 1, Aikaterini Anastasiou 1, Despoina Asouhidou 1, Efthimia Evgenikaki 1, Evangelia Sidira 1, Georgia Chatzika 1, Fani Makrovasili 1 1National Peripheral Histocompatibility Center, Hippokration General Hospital, Thessaloniki, Greece P157 DIFFERENT HLA-DPB1 ALLELE FREQUENCIES AMONG EARLY-ONSET AND ADULT-ONSET MULTIPLE SCLEROSIS PATIENTS AND HEALTHY CONTROLS, IN A HELLENIC COHORT Maria Anagnostouli 1, Serafeim Katsavos 1, Artemios Artemiadis 1 1Medical School of Athens National and Kapodistrian University, Aeginition Hospital, Athens, Greece P158 GENETIC HLA STUDY OF KURDS IN IRAQ, IRAN AND TBILISI (CAUCASUS, GEORGIA): RELATEDNESS AND MEDICAL IMPLICATIONS Antonio Arnaiz-Villena 1, Jose Palacio-Gruber 1, Ester Muñiz 1, Cristina Campos 1, Javier Alonso-Rubio 1, Ignacio Juarez 1, Jorge Nieto 1, Shadallah Fareq Salih 2, José Manuel Martín-Villa 1, Rawand Al-Qadi 2 1University Complutense,The Madrid Regional Blood Center (Centro de Transfusion), Madrid, Spain - 2Dohuk Specialized Laboratory Center, Dohuk, Iraq P159 ORIGIN OF AZERIS (IRAN) ACCORDING TO HLA GENES Antonio Arnaiz Villena 1, Jose Palacio-Gruber 1, Ester Muñiz 1, Diego Rey 1, Behrouz Nikbin 2, Hosein Nickman 2, Cristina Campos 1, Rawand Al-Qadi 3, José Manuel Martín-Villa 1, Ali Amirzargar 2 1University Complutense,The Madrid Regional Blood Center (Centro de Transfusion), Madrid, Spain - 2Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran - 3Dohuk Specialized Laboratory Center, Dohuk, Iraq P160 HLA-G~A HAPLOTYPES IN AMERINDIANS (ECUADOR): HLA-G*01:05N WORLD DISTRIBUTION Antonio Arnaiz Villena 1, Jose Palacio-Gruber 1, Mercedes Enriquez de Salamanca 1, Ignacio Juarez 1, Cristina Campos 1, Jorge Nieto 1, Ester Muñiz1, Rawand Al-Qadi 2, José Manuel Martín-Villa 1 1University Complutense,The Madrid Regional Blood Center (Centro de Transfusion), Madrid, Spain - 2Dohuk Specialized Laboratory Center, Dohuk, Iraq P161 NEW AND RARE ALLELES IN SOUTH TYROLS BONE MARROW REGISTRY DONORS 1 1 1 Cinzia Vecchiato , Evi Lochmann , Ivo Gentilini POSTER 1Ospedale di Bolzano, Bolzano, Italy
77 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P162 DETECTION OF A RARE ALLELIC VARIANT OF HLA-C*06 (C*06:76:02) IN A SPANISH PATIENT Cristina Abad-Molina 1, Mario Cárdaba-Arranz 1, Antonio Balas 2, Jose Luis Vicario 2, Antonio Orduña-Domingo 1 1Hospital Clínico Universitario de Valladolid, Valladolid, Spain - 2Centro de Transfusión de la Comunidad de Madrid, Madrid, Spain P163 SUSPECTED UNEQUAL CROSSING OVER AT THE HLA-DPB1 LOCUS: A CASE REPORT Caterina Fusco 1, Carla Cervelli 2, Raffaella Azzarone 2, Roberta Penta de Vera Aragona 1, Mario Toriello 1, Giovanna Maisto 1, Laura Auriemma 1, Mimmo Ripaldi 1, Franco Papola 2 1AORN Santobono-Pausilipon Dipartimento Oncologia SSD BaSCO, Napoli, Italy - 2Centro Regionale di Immunoematologia e Tipizzazione Tissutale ASL1, L’Aquila, Italy P164 STUDY OF THE ALLELIC FREQUENCIES OF A POPULATION OF BARRANQUILLA, COLOMBIA Carlos H. Parga Lozano 1, Franklin Torres 2, Aracely Garcia 2 1Universidad del Atlántico, Barranquilla, Colombia - 2Universidad Libre, Barranquilla, Colombia P165 A NEW UNUSUAL HLA-DQA1 ALLELE: DQA1*01Q:NEW Thomas M.C. Binder 1, Wolfgang Peter 2, Tobias Roth 2, Lena Krammes 2, Sikder N.I. Rabbi 3, Reinhard Kelsch 4, Matthias Marget 1, Marco Schäfer 2 1Medical Center Hamburg-Eppendorf, Hamburg, Germany - 2Stefan Morsch Foundation (SMS), Birkenfeld, Germany - 3Labaid Diagnostic limited, Dhaka, Bangladesh - 4University Clinics Münster, Münster, Germany P166 AN EXTRAORDINARY NEW HLA-B*13 ALLELE Thomas M.C. Binder 1, Wolfgang Peter 2, Tobias Roth 2, Peter Trojok 2, Nicole Siebert 2, Lena Krammes 2, Reinhard Kelsch 3, Marco Schäfer 2 1Medical Center Hamburg-Eppendorf, Hamburg, Germany - 2Stefan Morsch Foundation (SMS), Birkenfeld, Germany - 3University Clinics Münster, Münster, Germany P167 ASSOCIATION OF INTERLEUKIN-28B GENE POLYMORPHISMS AND HEPATITIS B CHRONIC INFECTION IN AN IRANIAN POPULATION Sadaf Asaei 1, Marzieh Jamalidoust 1, Mazyar Ziyaeyan 1, Maryam Zare 1, Mandana Namayandeh 1 1Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran P168 HLA-A, -B, -C, -DRB1, -DQA1, -DQB1 AND -DPB1 ALLELE AND HAPLOTYPE FREQUENCIES DEFINED BY NEXT GENERATION SEQUENCING IN A POPULATION OF EAST CROATIA BLOOD DONORS Stana Tokić 1, Veronika Žižková 2, Mario Štefanić 1, Saška Marczi 3, Katerina Sikorova 2, Marina Samardžija 3, Ljubica Glavaš-Obrovac 1, Martin Petrek 2 1Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia - 2Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic - 3Clinical Institute of Transfusion Medicine, Osijek University Hospital, Osijek, Croatia P169 GENETIC DISTANCES BASED ON HLA GENE FREQUENCIES BETWEEN THE RUSSIAN DONORS OF HEMATOPOIETIC STEM CELLS FROM MOSCOW AND OTHER RUSSIAN AND WORLDWIDE POPULATIONS Ekaterina G. Khamaganova 1, Elena P. Kuzminova 1, Alena R. Abdrakhimova 1, Regina S. Chapova 1, Konstantin V. Vasyukov 1, Tamara P. Chugreeva 1, Tatiana V. Gaponova 1, Valeriy G. Savchenko 1 1National Research Center for Hematology, Moscow, Russian Federation POSTER
78 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P170 HLA CLASS I ASSOCIATION STUDY WITH ALLOPURINOL INDUCED SCAR IN THE SOUTH TUNISIAN POPULATION Aida Charfi1 , Nadia Mahfoudh 1, Arwa Kamoun 1, Kamilia Ksouda 2, Hanen Affes 2, Amal Hriz 2, Khaled Zeghal 2, Hafedh Makni 1 1Immunology department, University Hospital Hedi Cheker, Sfax, Tunisia - 2Pharmacology department,University of Medicine, Sfax, Tunisia P171 NEXT GENERATION SEQUENCING REVEALS HLA-DPB1 DIVERSITY IN BRITISH BONE MARROW REGISTRY VOLUNTEERS FROM DIFFERENT ETHNIC GROUPS Juliette Brown1, Sue Davey1, John Ord1, Dimitra Niokou1, Winnie Chong1 and Colin J Brown1 Histocompatibility and Immunogenetics, NHSBT, Colindale, UK 1NHSBT, London, United Kingdom (Great Britain) P172 HLA-DRB1*03:24 - A DRB1*03:01-LIKE EXON 2 SEQUENCE IN TYPICAL DRB1*13:02- HAPLOTYPE Thomas M.C. Binder 1, Wolfgang Peter 2, Corinna B. Koehn 3, Lena Krammes 2, Tobias Roth 2, Christine Neuchel 4, Daniel Fuerst 4, Joannis Mytilineos 4, Kaimo Hirv 5, Reinhard Kelsch 6, Marco Schäfer 2, Thomas H. Eiermann 1 1Medical Center Hamburg-Eppendorf, Hamburg, Germany - 2Stefan Morsch Foundation (SMS), Birkenfeld, Germany - 3University Clinics Freiburg, Freiburg, Germany - 4German Red Cross Blood Transfusion Service, Baden-Wuerttemberg Hessen, Ulm, Germany and Institute of Transfusion Medicine, University of Ulm, Ulm, Germany - 5Center for Human Genetics and Laboratory Diagnostics, Martinsried, Germany - 6University Clinics Münster, Münster, Germany P173 NGS BASED HIGH-THROUGHPUT MICA AND MICB GENOTYPING OF 400,000 SAMPLES Carolin Massalski 1, Kathrin Lang 1, Jens Pruschke 2, Daniel Schefzyk 2, Jan Hofmann 2, Jürgen Sauter 2, André P. Mäurer 1, Alexander H. Schmidt 2, Vinzenz Lange 1 1DKMS Life Science Lab, Dresden, Germany - 2DKMS, Tübingen, Germany P174 IMMUNOGENETICS OF AGEING: NEW DATA IN THE NGS ERA Milena Ivanova 1, Bushra Al Hadra 1, Tsvetelin Lukanov 2, Antoaneta Nedilakova 2, Reem Ameen 3, Michela Mazzoco 4, Nicoletta Sacchi 4, Velizar Shivarov 5, Elissaveta Naumova 1 1Medical University, University Hospital Alexandrovska, Sofia, Bulgaria -2 University Hospital Alexandrovska, Sofia, Bulgaria - 3Kuwait University, Jabriya, Kuwait - 4Ospedale Galliera, Genova, Italy - 5University Hospital SofiaMed, Sofia, Bulgaria P175 A PATIENT CASE WITH SIMULTANEOUS GENE EXPRESSION OF THREE HLA-B ALLELIC VARIANTS DUE TO POINT MUTATION OBSERVED AT THE CO-EXPRESSED HLA-B*07:02 ALLELE Chrysanthi Tsamadou 1, Daniel Furst 1, Christine Neuchel 1, Hubert Schrezenmeier 1, Joannis Mytilineos 1 1German Red Cross Blood Transfusion Service, Baden-Wuerttemberg Hessen, Ulm, Germany and Institute of Transfusion Medicine, University of Ulm, Ulm, Germany P176 EXPLORATION OF VERY LONG-RANGE LINKAGE DISEQUILIBRIUM WITHIN THE EXTENDED HLA REGION Umut Özbek 1, Sandeep K. Singh 2, Amy E. Kennedy 3, M. Alejandro Barbieri 4, Johannes Dapprich 5, Ioanna Konidari 6, Jacob L. McCauley 6, Mehmet Tevfik Dorak 7 1Icahn School of Medicine at Mount Sinai; Tisch Cancer Institute, New York, NY, United States of America - 2Ohio State University, Columbus, OH, United States of America - 3National Cancer Institute, Bethesda, MD, United States of America - 4Florida International University, Miami, FL, United States of America - 5Generation Biotech, Lawrenceville, NJ, United States of America - 6University of Miami, John P. Hussman Institute for Human Genomics, Miami, FL, United States of America -
7Kingston University London, Kingston, United Kingdom (Great Britain) POSTER
79 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P177 QUANTIFICATION OF HLA-C SURFACE EXPRESSION IN 400 HEALTHY GERMAN BLOOD DONORS Chrysanthi Tsamadou 1, Daniel Furst 1, Markus Rojewski 2, Christine Neuchel 1, Sixten Körper 3, Hubert Schrezenmeier 1, Joannis Mytilineos 1 1German Red Cross Blood Transfusion Service, Baden-Wuerttemberg Hessen, Ulm, Germany and Institute of Transfusion Medicine, University of Ulm, Ulm, Germany - 2Institute of Transfusion Medicine, University of Ulm, Ulm, Germany - 3Institute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Transfusion Service, Baden Wuerttemberg Hessen, Ulm, Germany P178 BW4 AND BW6 EPITOPE DISTRIBUTION ON MHC CLASS I MOLECULES OF OLIVE BABOONS Nanine de Groot 1, Marit K.H. van der Wiel 1, Gaby G.M. Doxiadis 1, Nel Otting 1, Natasja G. de Groot 1, Nicolas Poirier 2, Antoine Blancher 3, Ronald E. Bontrop 1 1Biomedical Primate Research Centre, Rijswijk, Netherlands - 2INSERM UMR 1064, Nantes, France - 3Laboratoire d’immunologie - Laboratoire d’Immunogénétique moléculaire EA 3034 - CHU de Toulouse -Faculté de médecine de Purpan, Université Paul Sabatier Toulouse 3, Toulouse, France P179 CONFIRMED OR WELL-DETERMINED (CWD) HLA HAPLOTYPES IN EUROPE: A PRELIMINARY CATALOGUE OF THE EFI POPULATION GENETICS WORKING GROUP Alicia Sanchez-Mazas 1, José M. Nunes 1, Marco Andreani 2, Zorana Grubic 3, Derek Middleton 4, Stéphane Buhler 5, Katharina Fleischhauer 6 1University of Geneva, Geneva, Switzerland - 2Laboratory of Immunogenetics and Transplant Biology - IME Foundation at Polyclinic of Tor Vergata, Rome, Italy - 3University Hospital Centre Zagreb, Zagreb, Croatia - 4Royal Liverpool and Broadgreen University Hospital, Liverpool, United Kingdom (Great Britain) - 5Geneva University Hospitals, Geneva, Switzerland - 6Essen University Hospital, Essen, Germany P180 BUILDING A HIGH RESOLUTION HAPLOTYPE DATABASE FOR 11 HUMAN LEUKOCYTE ANTIGEN LOCI FROM FAMILY TRIOS Evan Kountouris 1, Douglas Levinson 2, Marcelo A. Fernández-Viña 3, Hanna Ollila 1 Emmanuel Mignot 4, Ming Tsuang 5, Stephen Glatt 6, Ming Li 1, Michael Mindrinos 1 1Immucor, Mountain View, United States of America - 2Stanford University School of Medicine, Palo Alto, United States of America - 3Stanford University Medical Center, Palo Alto, United States of America - 4Stanford Center for Sleep Sciences and Medicine, Palo Alto, United States of America - 5University of California San Diego, San Diego, United States of America - 6SUNY Upstate Medical University, Syracuse, United States of America P181 MARKOV CHAIN MODELLING BRINGS NEW CLUES ON HLA EVOLUTIONARY HISTORY Thomas Goeury 1, Jose M. Nunes 1, Alicia Sanchez-Mazas 1 1University of Geneva, Geneva, Switzerland P182 HLA-C ALLELE SPECIFIC EXPRESSION IN CHINESE HAN POPULATION Jiang Li 1, Wang Jue 2, Qiang Chen 1 1Institute of Blood Transfusion, Chinese Academy of Medical Sciences And Sichuan Cord Blood Bank, Chengdu, China - 2Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Chengdu, China P183 ANALYSIS OF NEW, VERY RARE AND RARE HLA ALLELES AMONG VOLUNTEER HEMATOPOIETIC STEM CELL DONORS IN CROATIAN BONE MARROW DONOR REGISTRY Marija Kamenaric Burek 1, Zorana Grubic 1, Marija Maskalan 1, Katarina Stingl Jankovic 1, Danijela Clekovic 1, Renata Zunec 1 1University Hospital Centre Zagreb, Zagreb, Croatia POSTER
80 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P184 APPROXIMATING ADMIXTURE IN LATIN AMERICAN POPULATIONS USING ANALYSIS OF HIGH-RESOLUTION HLA EXTENDED HAPLOTYPES: DIFFERENTIAL ADMIXTURE PROPORTIONS IN NEIGHBORING COUNTRIES Esteban Arrieta-Bolaños 1, Víctor Acuña-Alonzo 2, Rodrigo Barquera 3, Juan José Madrigal-Sánchez 4, Jeremy E. Stein 5, Priscilla Órlich-Pérez 6, María José Moreira-Espinoza 7, Edel Paredes-Carias 7, Yondra Vanegas-Padilla 7, Lizbeth Salazar-Sánchez 4, J. Alejandro Madrigal 8, Steven G.E. Marsh 8, Bronwen E. Shaw 9 1Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany - 2Laboratorio de Genética Molecular, Escuela Nacional de Antropología e Historia, México City, Mexico - 3Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany - 4Escuela de Medicina, Universidad de Costa Rica, San José, Costa Rica - 5Anthony Nolan Research Institute, Royal Free Hospital, London, United Kingdom (Great Britain) - 6División de Banco de Células Madre, Laboratorio Clínico, Hospital San Juan de Dios, San José, Costa Rica - 7Departamento de Ciencias Morfológicas, Universidad Nacional Autónoma de Nicaragua, León, Nicaragua - 8Anthony Nolan Research Institute & UCL Cancer Institute, London, United Kingdom (Great Britain) - 9Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, United States of America P185 THE EFFECT OF HLA AND SNPS ON ESRD DEVELOPMENT IN IGAN PATIENTS Cigdem Kekik 1, Sonay Temurhan 1, Sebahat U Akgul 1, Yasar K Caliskan 1, Yasemin Ozluk 1, Serra Ertan 1, Erol Demir 1, Figen Abatay 1, Halil Yazici 1, Aydin Turkmen 1, Kilicarslan Isik 1, Mehmet S Sever 1, Fatma Oguz Savran 1 1Istanbul Faculty of Medicine, Istanbul, Turkey P186 MAJOR HISTOCOMPATIBILITY COMPLEX ALLELE PERSISTENCE IN EURASIA AND AMERICA IN THE GENUS CARDUELIS (GOLDFINCHES) DURING MILLION YEARS Antonio Arnaiz-Villena 1, Valentín Ruiz-del-Valle 1, Ester Muñiz1, Jose Palacio-Gruber1, Cristina Campos 1, Eduardo Gomez- Casado 1, José Manuel Martín-Villa 1, Ignacio Serrano-Vela 1 1University Complutense, The Madrid Regional Blood Center (Centro de Transfusion), Madrid, Spain P187 HLA GENES IN ATLANTIC CELTIC POPULATIONS: ARE CELTS IBERIANS? Antonio Arnaiz-Villena 1, Ana Carballo 1, Ignacio Juarez 1, Ester Muñiz 1, Cristina Campos 1, Rawand Al-Qadi 2, Jorge Nieto 1, José Manuel Martín-Villa 1, Jose Palacio-Gruber 1 1University Complutense, The Madrid Regional Blood Center (Centro de Transfusion), Madrid, Spain - 2Dohuk Specialized Laboratory Center, Dohuk, Iraq P188 MICA AND NKG2D DISEASE-COMMON VARIANTS IN A FRENCH COHORT OF PATIENTS WITH SPONDYLOARTHRITIS Marie Fechtenbaum 1, Judith Desoutter 1, Vincent Goeb 1, Nicolas Guillaume 1 1Amiens University Medical Center, Amiens, France P189 HIGH RESOLUTION HLA-A, -B, -C, -DRB1 AND -DQB1 ALLELE AND HAPLOTYPE FREQUENCIES FOR ARAB DONORS IN THE HADASSAH BONE MARROW DONOR REGISTRY Amal Bishara 1, Michael Halagan 2, Chaim Brautbar 1, Shoshana Israel 1, Martin Maiers 2, Abeer Madbouly 2 1Hadassah-Hebrew University Medical Center, Jerusalem, Israel - 2National Marrow Donor Program, Minneapolis, MN, United States of America P190 THE RELEVANCE OF NGS TYPING IN UNRAVELING THE DIVERSITY OF 11 HLA LOCI TYPED IN THE MEXICAN MESTIZOS FROM OAXACA, MEXICO Andrea Munguia 1, Lisa E. Creary 2, Marcelo A. Fernández-Viña 2, Betsy González 3, Hilario Flores-A 3, Clara Gorodezky 3 1Instituto de Diagnóstico & Referencia Epidemiológicos-InDRE, Secretary of Health, México City, Mexico - 2Stanford University School of Medicine, Palo Alto, CA, United States of America - 3Instituto de Diagnóstico & Referencia Epidemiológicos-InDRE,
Secretary of Health & Fundación comparte Vida A.C., México City, Mexico POSTER
81 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P191 THE IMMUNOGENETIC FINGERPRINT OF THE INHABITANTS OF THE ITALIAN CALABRIA REGION: DISTRIBUTION OF HLA-A, -B, -C ALLELES IN FOUR PROVINCES COMPARED TO ELEVEN MODERN DESCENDANTS OF THEIR INVADERS Cristina Capittini 1, Marina Francone 2, Valeria Calantoni 2, Rita E. Saladino 2, Annalisa De Silvestri 1, Carmine Tinelli 3, Giuseppa Romeo 2 1IRCCS Policlinico San Matteo Foundation, Pavia, Italy - 2A.O. Bianchi Melacrino Morelli, Reggio Calabria, Italy - 3IRCCS Policlinico San Matteo Foundation, Pavia, Italy P192 DISTRIBUTION OF HLA-DRB1 ALLELES ASSOCIATED WITH RHEUMATOID ARTHRITIS IN SPLIT- DALMATIA COUNTY IN SOUTHERN CROATIA Ivanka Marinovic 1, Sonja Jaman 1, Esma Cecuk-Jelicic 1, Duska Martinovic-Kaliterna1, Jela Mratinovic-Mikulandra 1 1University Hospital Centre Split, Split, Croatia P193 IMPACT OF HLA-A~B~DRB1 HAPLOTYPE POLYMORPHISMS ON DONOR SELECTION IN HEMATOPOIETIC STEM CELL TRANSPLANTATION PROGRAM IN CROATIA Marija Maskalan 1, Zorana Grubic 1, Marija Burek Kamenaric 1, Danijela Svilicic 1, Katarina Stingl Jankovic 1, Renata Zunec 1 1University Hospital Centre Zagreb, Zagreb, Croatia P194 HLA PROFILES IN THE POPULATION OF MOLDOVA Vera Sali1, Corina Cianga2,3, Natalia Isac1, Elena Cuiban1, Daniela Constantinescu2,3, Camelia Mihaila3, Petru Cianga2,3 1 HLA Laboratory, Republican Clinical Hospital Timofei Mosneaga, Chisinau, Republic of Moldova - 2 Department of Immunology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, Romania - 3 Laboratory of Immunology and Genetics, “Sf. Spiridon” Hospital, Iasi, Romania
NK & NON-MHC P195 A CONFIRMATIVE STUDY TO VERIFY THE ACCURACY OF OUR NGS BASED WORKFLOW AND SOFTWARE FOR HIGH-RESOLUTION KIR GENOTYPING Bianca Heyn 1, Jill A. Hollenbach 2, Paul J. Norman 3, Annett Heidl 1, Alexander H. Schmidt 4, Jürgen Sauter 4, Vinzenz Lange 1 1DKMS Life Science Lab, Dresden, Germany - 2University of California, San Francisco School of Medicine, San Francisco, United States of America - 3University of Colorado, Denver, CO, United States of America - 4DKMS, Tübingen, Germany P196 ROLE OF TELOMERIC INHIBITOR KIR GENES IN ALCOHOL CIRRHOSIS Isabel Legaz 1, José M. Bolarin 2, José A. Campillo 2, Maria R. Moya-Quiles 2, Lourdes Gimeno 2, Ana M. Garcia-Alonso 2, Maria Rocio Alvarez-Lopez 2, Alfredo Minguela 2, Manuel Muro 2 1University of Murcia, Murcia, Spain - 2Clinic University Hospital Virgen Arrixaca, Murcia, Spain P197 IDENTIFICATION OF MHC CLASS IB LIGANDS FOR STIMULATORY AND INHIBITORY LY49 RECEPTORS AND INDUCTION OF POTENT NK ALLORESPONSES IN RATS Ke-Zheng Dai 1, John Torgils Vaage 1, Christian Naper 1 1Oslo University Hospital - Rikshospitalet, Oslo, Norway P198 KIR 3DL1-EDU, HLA GENOTYPES AND KIR HAPLOTYPE INFLUENCE CLINICAL OUTCOME OF HIGH-RISK YOUNG MULTIPLE MYELOMA PATIENTS TREATED UP-FRONT WITH NOVEL AGENTS Sebastiana Toscano 1, Fabrizio Puglisi 2, Alessandra Romano 2, Etta Conticello 2, Marina Parisi 2, Valeria Calafiore2 , Enrica Martino 2, Salvatore Leotta 2, Francesco Di Raimondo 2, Grazia Sortino 1, Maria Pia Azzaro 1 POSTER 1 Tissue Typing Laboratory - Hematology and Bone Marrow Transplantation Units - Policlinico Vittorio Emanuele, Catania, Italy - 2UOC Hematology and Bone Marrow Transplantation Units - AOU Policlinico Vittorio Emanuele, Catania, Italy
82 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P199 ASSOCIATION OF KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR KIR2DS1 WITH PSORIASIS IS INDEPENDENT OF HLA-C*06:02 Sandro Orrù 1, Maria Antonietta Montesu 2, Nicola Orrù 3, Erika Giuressi 3, Rosanna Satta 2, Giuliana Onnis 2, Paola Ragatzu 1, Daniela Diana 1, Selene Cipri 1, Roberto Littera 3, Alberto Cauli 4, Carlo Carcassi 1 1Medical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy - 2Dermatology Unit, Department of Surgical, Microsurgical and Medical Sciences, University of Sassari, Sassari, Italy - 3Medical Genetics, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Cagliari, Italy - 4Chair of Rheumatology and Rheumatology Unit, AOU University Clinic of Cagliari, Cagliari, Italy P200 KILLER-CELL IMMUNOGLOBULIN-LIKE RECEPTOR GENES AND HLA IN RELAPSING- REMITTING MULTIPLE SCLEROSIS Eleonora Cocco 1, Elena Congeddu 2, Selene Cipri 2, Paola Ragatzu 2, Sara Lai 3, Rita Porcella 3, Francesco Alba 3, Valentina Loi 3, Maria Serra 3, Roberta Maddi 3, Cristina Melis 4, Lucia Schirru 4, Daniela Corongiu 4, Stefania Tranquilli 1, Jessica Frau 1, Roberto Cusano 5, Maurizio Melis 2, Roberta Murru 3, Carlo Carcassi 2 1Multiple Sclerosis Center, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy - 2Medical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy - 3Medical Genetics, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Cagliari, Italy - 4Multiple Sclerosis Center, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Cagliari, Italy - 5Center for Advanced Studies, Research and Development (CRS4), Pula, Italy P201 KIR3DL1/S1 NATURAL KILLER CELL IMMUNOGLOBULIN LIKE RECEPTORS (KIR) DISTRIBUTION AND THEIR HLA CLASS I LIGANDS IN MEXICAN MESTIZOS FROM MEXICO CITY Betsy González 1, Guadalupe Sánchez 2, Andrea Munguia 3, Miriam Valencia 3, Hilario Flores-A 1, Clara Gorodezky 1 1Instituto de Diagnóstico & Referencia Epidemiológicos-InDRE, Secretary of Health & Fundación comparte Vida A.C., México City, Mexico - 2Fundación Comparte Vida, A.C., Mexico City, Mexico - 3Instituto de Diagnóstico & Referencia Epidemiológicos-InDRE, Secretary of Health, México City, Mexico P202 DIVERSITY OF C1, C2, BW4, A3/11 AND BW6 AMINO ACID MOTIFS IN WHOLE HLA:KIR INTERFACE Slawomir Gwozdowicz 1, Klaudia Nestorowicz 1, Urszula Szlendak 1, Jacek Nowak 1 1Institute of Hematology and Transfusion Medicine, Warsaw, Poland P203 EVALUATION OF NK CELL CYTOTOXICITY BIOMARKERS OF TUMOR PROGRESSION IN BREAST CANCER Angelica Canossi 1, Anna Aureli 1, Tiziana Del Beato 1, Giorgio Novelli 2, Oreste Buonomo 2, Giuseppe Sconocchia 3 1CNR Translational Pharmacology, L’Aquila, Italy - 2Department of Systems Medicine, Rome, Italy - 3CNR Translational Pharmacology, Rome, Italy P204 THE HYBRID GENE KIR2DS2*005 IS CARRIED BY TWO HAPLOTYPES DIFFERING IN THE TELOMERIC REGION Maria Bono 1, Alice Bertaina 2, Edoardo Lanino 1, Marco Zecca 3, Daniela Pende 4, Alessandro Moretta 5, Franco Locatelli 2, Lorenzo Moretta 6, Cristina Bottino 5, Michela Falco 1 1Institute Giannina Gaslini, Genoa, Italy - 2IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy - 3IRCCS Policlinico San Matteo Foundation, Pavia, Italy - 4IRCCS Ospedale Policlinico San Martino, Genoa, Italy - 5Università degli Studi di Genova, Genoa, Italy - 6Ospedale Pedriatico Bambino Gesù, Rome, Italy P205 IDENTIFICATION AND EXPRESSION OF NOVEL IMMUNOGLOBULIN-LIKE GENES ENCODED BY THE LEUKOCYTE RECEPTOR COMPLEX (LRC) IN PIGS John C. Schwartz 1, John A. Hammond 1 POSTER 1The Pirbright Institute, Woking, United Kingdom (Great Britain)
83 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P206 INFLUENCE OF KIR2DL2/L3 GENES IN THE DEVELOPMENT OF ALCOHOLIC CIRRHOSIS Isabel Legaz 1, José M. Bolarín2, José A. Campillo 2, Maria R. Moya-Quiles 2, Lourdes Gimeno 2, Ana M. Garcia-Alonso 2, Maria Rocio Alvarez-Lopez 2, Alfredo Minguela 2, Manuel Muro 2 1University of Murcia, Murcia, Spain - 2Clinic University Hospital Virgen Arrixaca, Murcia, Spain
REPRODUCTION, AUTOIMMUNITY, INFECTION & CANCER P207 ANALYSIS OF THE FREQUENCIES OF HLA-C LOCUS IN PATIENTS WITH RHEUMATIC DISEASES Cristina Abad-Molina 1, Miriam Vilches-Moreno 2, Mario Cárdaba-Arranz 1, Mercedes Nocito-Colón1, Antonio Orduña- Domingo 1, Jesús Ontañón-Rodríguez 3 1Hospital Clínico Universitario de Valladolid, Valladolid, Spain - 2Hospital Puerta del Mar, Cádiz, Spain - 3Hospital General Albacete, Albacete, Spain P208 HLA ALLELE INVESTIGATION IN PSORIASIS AS A POSSIBLE TRANSLATIONAL APPROACH Sara Autolitano 1, Valeria Calantoni 1, Giuseppa Romeo 1, Marina Francone 1, Natale Imbesi 1, Francesco Turiano 1, Silvia Cafarelli 1, Anna Maria Verduci 1, Rita E. Saladino1 1A.O. Bianchi Melacrino Morelli, Reggio Calabria, Italy P209 TNF-ALPHA GENE POLYMORPHISMS IN ROMANIAN PATIENTS WITH CROHNS DISEASE M. Olivia Popa 1, Cristian Tieranu 2, Mihai Bojinca 1, Monica I. Dutescu 3, Ioana Tieranu 1, Constantin Bara 1, Mircea Diculescu 1 1University of Medicine and Pharmacy ‘Carol Davila’, Bucharest, Romania - 2Elias University Emergency Hospital, Bucharest, Romania - 3’Prof. Dr. C. T. Nicolau’ National Institute of Blood Transfusion, Bucharest, Romania P210 HLA CLASS I MOLECULES AS KIR LIGANDS IN PSORIASIS SUSCEPTIBILITY Marco Guarene 1, Vittorio Bolcato 1, Adriana Piccolo 1, Ilaria Sbarsi 1, Cinzia Pizzochero1, Rosalia Cacciatore 1, Paola Bergamaschi 1, Annamaria Pasi 1, Valeria Brazzelli 1 1IRCCS Policlinico San Matteo Foundation, Pavia, Italy P211 COMPARISON OF HLA-DQA1, DQB1, AND DRB1 ALLELES BETWEEN HEALTHY INDIVIDUALS AND CELIAC PATIENTS Tulay Kilicaslan Ayna 1, Asli Ozkizilcik Kocyigit 1, Asli Eldem 1, Derya Gulec 1, Murat Kilicoglu 1, Mustafa Soyoz 1 1Tepecik Training and Research Hospital, Izmir, Turkey P212 HLA AND NEFRIT TUBULES- INTERSTITIAL AND UVEITE Rita D’Auria 1, Antonella Manzo 1, Marika Petrillo 1, Antonio Vitale 2, Maria Majorana2, Michele Cirella 1, Agata De Feo 1, Paolo di Maio 1, Antonio De Sapio 1, Anna Elisa Laserra 1 1A.O.R.N. San G. Moscati SIMT, Avellino, Italy - 2A.O.R.N. San G. Moscati Pediatria, Avellino, Italy P213 INVESTIGATION OF HLA-B*51 SUB-ALLELES IN TURKISH PATIENTS WITH BEHCETS DISEASE Sinem Topcu 1, Tulay Kilicaslan Ayna 1, Handan Kelekci 2, Murat Kilicoglu 1, Burcu Cerci Gurbuz 1, Asli Ozkizilcik Kocyigit 1, Mustafa Soyoz 1 1Tepecik Training and Research Hospital, Izmir, Turkey - 2İzmir Katip Celebi University Atatürk Education and Research Hospital, Izmir, Turkey POSTER
84 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P214 ASSOCIATIONS OF CYTOKINE POLYMORPHISMS AND CYTOGENETIC PROFILES IN MULTIPLE MYELOMA PATIENTS FROM THE NORTH-WEST REGION OF RUSSIA Anastasia Pavlova 1, Irina Pavlova 2, Ludmila Bubnova 2, Stanislav Bessmeltsev 2, Elizaveta Kleina 2, Andrey Gariffulin 2, Irina Martynkevich 2, Sergey Voloshin 2, Aleksandr Chechetkin 2 1Russian Institute of Haematology and Transfusion; Saint-Petersburgs Multidisciplinary Medical Center named after I.P. Pirogov, St. Petersburg, Russian Federation - 2Russian Institute of Haematology and Transfusiology, St. Petersburg, Russian Federation P215 GENETIC DIVERSITY OF INTERLEUKIN-6 AND ITS RECEPTOR AND PLASMA INTERLEUKIN-6 LEVELS IN BIPOLAR DISORDER: AN INDO-FRENCH STUDY Aparna Sundaresh 1, José Oliveira 1, Raj Kumar Chinnadurai 2, Ravi Philip Rajkumar2, Lylia Hani 3, Rajagopal Krishnamoorthy 3, Marion Leboyer 1, Vir Singh Negi 2, Ryad Tamouza 1 1Inserm U955, Créteil, France - 2Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India - 3Hôpital Saint-Louis, Paris, France P216 MOLECULAR ANALYSIS OF HUMAN PARVOVIRUS B19 NON-STRUCTURAL PROTEIN GENE EXPRESSION IN TRANSFECTED HEK-293T EPITHELIAL CELL LINE AND ITS CORRELATION WITH ACTIVATION OF INFLAMMATORY RESPONSE Sedigheh Jalali 1, Abbas Behzad-Behbahani 1, Gholam-Reza Rafiei-Dehbidi1 , Shirin Farjadian 1, Ali Farhadi 1 1Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran P217 SCHIZOPHRENIA AND HLA: WORK IN PROGRESS ABOUT HLA TYPING USEFULNESS AND DIAGNOSTIC THERAPEUTIC OUTLOOKS Rita E. Saladino 1, Giuseppa Romeo 1, Marina Francone 1, Valeria Calantoni 1, Sara Autolitano 1, Alessia Stranges 1, Silvia Cafarelli 1, Anna Maria Verduci 1, Manuel Mercurio 1, Natale Imbesi 1, Michele Zoccali 2, Giuseppe Libri 2, Carmela Palumbo 2, Filomena Salvadori 2 1A.O. Bianchi Melacrino Morelli, Reggio Calabria, Italy - 2Azienda Sanitaria Provinciale n. 5, Reggio Calabria, Italy P218 GENETIC VARIABILITY IN TLR10 GENE MAY MODULATE THE SUSCEPTIBILITY TO RHEUMATOID ARTHRITIS AND RESPONSE TO TREATMENT WITH ITNF-ALPHA Barbara Wysoczanska 1, Marta Puchala 1, Jerzy Swierkot 2, Katarzyna Kolossa 3, Slawomir Jeka 3, Katarzyna Bogunia-Kubik 1 1Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland - 2Wroclaw Medical University, Wrocław, Poland - 3Hospital University Number 2 Jana Biziela, Bydgoszcz, Poland P219 HLA-I-NEGATIVE/PD-L1-POSITIVE NON-SMALL CELL LUNG CANCER HAS MORE AGGRESSIVE PHENOTYPE AND A LOW GRADE OF IMMUNE INFILTRATION Francisco Perea 1, Abel Sánchez-Palencia 1, Mercedes Gómez-Morales 2, Míguela Méndez García 1, Ángel Concha 3, Amanda Rocío González-Ramírez 4, Teresa Cabrera 5, Federico Garrido 1, Francisco Ruiz-Cabello 1, Natalia Aptsiauri 5 1Hospital Universitario Virgen de las Nieves, Granada, Spain - 2 Universidad de Granada,, Granada, Spain - 3Complejo Hospitalario Universitario, La Coruña, Spain - 4Fundación de Investigación Biosanitaria Alejandro Otero, Granada, Spain - 5Universidad de Granada, Granada, Spain P220 ALLELE C07 AND PSORIASIS Rita D’Auria 1, Antonella Manzo 1, Marika Petrillo 1, Raffaele Iandoli 2, Michele Cirella1, Antonio Bottone 1, Paolo di Maio 1, Mattia Verosimile 1, Vito Colacurcio 1, Anna Elisa Laserra 1 1A.O.R.N. San G. Moscati SIMT, Avellino, Italy - 2A.O.R.N. San G. Moscati Dermatologia, Avellino, Italy POSTER
85 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P221 THE ASSOCIATION OF IL-17 GENE POLYMORPHISMS AND THE RISK OF BLADDER CANCER IN A POLISH POPULATION: PRELIMINARY DATA Anna Tomkiewicz 1, Wojciech Krajewski 2, Anna Kolodziej 2, Romuald Zdrojowy 2, Janusz Dembowski 2, Anna Partyka 1, Irena Frydecka 1, Lidia Karabon 1 1Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland - 2Wroclaw Medical University, Wroclaw, Poland P222 ROLE OF HLA-G EXON 8 POLYMORPHISM IN CONFERRING GENETIC SUSCEPTIBILITY TO TYPE 1 DIABETES AMONG NORTH INDIANS Uma Kanga 1, Manish Mourya 1, Nikhil Tandon 2, Poonam Coshic 3 1Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India - 2Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India - 3Transfusion Medicine, All India Institute of Medical Sciences, New Delhi, India P223 IL-23R GENE POLYMORPHISMS CONFERS SUSCEPTIBILITY TO BLADDER CANCER IN A POLISH POPULATION: A PRELIMINARY DATA Anna Tomkiewicz 1, Anna Partyka 1, Wojciech Krajewski 2, Anna Kolodziej 2, Janusz Dembowski 2, Romuald Zdrojowy 2, Irena Frydecka 1, Lidia Karabon 1 1Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland - 2Wroclaw Medical University, Wroclaw, Poland P224 BTLA GENE POLYMORPHISMS IN MULTIPLE MYELOMA IN A POLISH POPULATION Anna Partyka 1, Dariusz Woszczyk 2, Marek Kielbinski 3, Irena Frydecka 1, Lidia Karabon 1 1Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland - 2State Hospital, Opole, Poland - 3Medical University, Wroclaw, Poland P225 LOH AND DOWNREGULATION OF THE APM COMPONENTS ARE THE KEY MECHANISMS OF THE LOSS OF HLA CLASS I EXPRESSION IN LUNG CANCER Francisco Perea 1, Martin Kerick 2, Monica Bernal 1, Javier Martin 2, Abel Sánchez-Palencia 1, Teresa Cabrera 3, Federico Garrido 1, Natalia Aptsiauri 3, Francisco Ruiz-Cabello 1 1Hospital Universitario Virgen de las Nieves, Granada, Spain - 2Instituto de Parasitology Biomedicina López Neyra, CSIC, Granada, Spain - 3Universidad de Granada, Granada, Spain P226 C4 COPY NUMBER VARIATIONS IN PSYCHIATRIC AND AUTOIMMUNE DISORDERS Christina Mary Mariaselvam 1, Aparna Sundaresh 1, Céline Manier 1, Ravi Philip Rajkumar 2, Rajagopal Krishnamoorthy 3, Marion Leboyer 1, Vir Singh Negi 2, Ryad Tamouza 1 1Henri Mondor Hospital, Créteil, France - 2Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India - 3Saint Louis Hospital, Paris, France P227 PREVALENCE OF HLA B*57 AMONG HIV-1 POSITIVE PATIENTS IN THE AEGEAN REGION OF TURKEY Murat Kilicoglu 1, Derya Gulec 1, Tulay Kilicaslan Ayna 1, Mustafa Soyoz 1, Sukran Kose 1 1Tepecik Training and Research Hospital, Izmir, Turkey POSTER
86 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P228 ROLE OF HLA-G IN AUTOIMMUNE HEPATITIS Roberto Littera 1, Sara Lai 1, Elena Congeddu 2, Paola Ragatzu 2, Selene Cipri 2, Maria Donatella Valentini 1, Luisella Cappai 1, Rita Porcella 1, Francesco Alba 1, Maria Serra 1, Valentina Loi 1, Roberta Maddi 1, Maurizio Melis 2, Roberto Cusano 3, Marcello Trucas, Sandro Orrù 2, Luchino Chessa 5, Simona Onali 5, Francesco Figorilli 5, Carlo Carcassi 2 1Medical Genetics, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Cagliari, Italy - 2Medical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy - 3Center for Advanced Studies, Research and Development (CRS4), Pula, Italy - 4School of Clinical Pathology, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy - 5Center for the Study of Liver Diseases, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy P229 THE ASSOCIATION OF ERAP1 AND ERAP2 SINGLE NUCLEOTIDE POLYMORPHISMS WITH RECURRENT SPONTANEOUS ABORTION Karolina Wilczyńska 1, Andrzej Wiśniewski 1, Aleksandra Bylińska 1, Ewa Barcz 2, Andrzej Malinowski 3, Jacek Wilczyński 4, Piotr Kuśnierczyk 1, Izabela Nowak 1 1Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland - 2Medical University of Warsaw, Warszawa, Poland - 3Polish Mothers Memorial HospitalResearch Institute, Łódź, Poland - 4Medical University of Lodz, Łódź, Poland P230 DISTRIBUTION OF HLA CLASS I AND CLASS II ALLELES IN IGA DEFICIENCY PATIENTS FROM CANTABRIA (NORTHERN SPAIN) Laura Riesco Dávila 1, Fernando Ausín Ortega 1, Marcos López Hoyos 1, J. Gonzalo Ocejo-Vinyals 1 1Hospital Universitario Marqués de Valdecilla, Santander, Spain P231 CAN WE WIN OR CAN'T WIN CANCER? RESEARCH SHOWS US A REAL HOPE Anna Maria Berghella 1, Anna Aureli 1, Angelica Canossi 1, Ida Anna Contasta 1, Giuseppe Marulli 2, Roberto Lattanzio 3, Giancarlo Di Gregorio 4, Tiziana Del Beato 1, Enzo Secinaro 5, Patrizia Pellegrini 1 1Institute of Translational Pharmacology, L'Aquila, Italy - 2L'Aquila Hospital, l'Aquila, Italy - 3Popoli-Pescara Hospital, Popoli, Italy - 4Popoli-Pescara Hospital, Italy - 5Chieti-Hospital, Italy P232 HLA-DQ GENOTYPE AND RISK FOR COELIAC DISEASE IN NORTHERN GREEK PATIENTS Panagiota Lazidou 1, Maria Fotoulaki 1, Alexandra Fleva 1, Fotini Sotiriadou 1, Maria Markopoulou 1, Christina Aggelopoulou 1, Athanasios Dardas 1, Anastasia Giannakou 1 1Papageorgiou General Hospital, Thessaloniki, Greece P233 BEHCET LIES IN THE EYE OF THE B-HOLDER Sally Elfishawi1 , Ghada Mossallam 1, Mohanad Elfishawi2 , Helma Bruin 3 Loes A.L. van de Pasch 3 Erik H. Rozemuller 3, Khaled Abdelmonen Zaky 4, Marcelo A. Fernández-Viña 5 1National Cancer Institute, Cairo University, Cairo, Egypt - 2Kasr Alaini School of Medicine & Icahn School of Medicine at Mount Sinai, Egypt - 3GenDx, Utrecht, Netherlands - 4Faculty of Medicine, Azhar university, Egypt - 5Stanford University School of Medicine, Palo Alto, United States of America P234 ICOS GENE POLYMORPHISMS IN MULTIPLE MYELOMA IN A POLISH POPULATION Anna Partyka 1, Dariusz Woszczyk 2, Marek Kielbinski 3, Irena Frydecka 1, Lidia Karabon 1 1Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland - 2State Hospital, Opole, Poland - 3Medical University, Wroclaw, Poland P235 ASSOCIATION OF HLA-DRB1*15 ANTIGEN WITH ENDOTHELIAL DAMAGE IN RELAPSING- REMITTING MULTIPLE SCLEROSIS PATIENTS J. Gonzalo Ocejo-Vinyals 1, Laura Riesco Dávila 1, Vicente González Quintanilla 1, María Toriello Suárez 1, Sara Pérez Pereda 1, Fernando Ausín Ortega 1, Agustín Oterino Durán 1 POSTER 1Hospital Universitario Marqués de Valdecilla, Santander, Spain
87 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P236 GWAS IDENTIFIED STRONG ASSOCIATION OF HLA-DR/DQ WITH CHILDHOOD STEROID- SENSITIVE NEPHROTIC SYNDROME IN THE JAPANESE POPULATION Katsushi Tokunaga 1, Xiaoyuan Jia 1, Tomoko Horinouchi 2, Yuki Hitomi 1, Akemi Shomo 2, Seik-Soon Khor 1, Yosuke Omae 1, Kaname Kojima 3, Yosuke Kawai 3, Masao Nagasaki 3, Kandai Nozu 2, Kazumoto Iijima 2 1University of Tokyo, Graduate School of Medicine, Tokyo, Japan - 2Kobe University Graduate School of Medicine, Kobe, Japan - 3Tohoku Medical Megabank Organization, Sendai, Japan P237 POLYMORPHISMS AND EXPRESSION OF PRO-INFLAMMATORY CYTOKINES IN PATIENTS WITH RHEUMATOID ARTHRITIS Joanna Wielińska 1, Marta Dratwa 1, Jerzy Swierkot 2, Lucyna Korman 2, Monika Chaszczewska-Markowska 1, Barbara Wysoczańska 1, Katarzyna Bogunia-Kubik 3 1Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland - 2Wroclaw Medical University, Wrocław, Poland - 3Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland P238 KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR AND HLA-C POLYMORPHISMS IN RECURRENT IMPLANTATION FAILURE Karolina Wilzyńska 1, Paweł Radwan 2, Michał Radwan 2, Jacek Wilczyński 3, Andrzej Malinowski 4, Ewa Barcz 5, Rafał Płoski 5, Piotr Kuśnierczyk 1, Izabela Nowak 1 1Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland - 2Gameta Hospital, Rzgów Poland - 3Medical University of Lodz, Łódź, Poland - 4Polish Mothers Memorial Hospital Research Institute, Łódź, Poland - 5Medical University of Warsaw, Warszawa, Poland P239 HLA HAPLOTYPE DISTRIBUTION AND RISK OF CELIAC DISEASE IN PATIENTS FROM CANTABRIA (NORTHERN SPAIN) Laura Riesco Dávila 1, Fernando Ausín Ortega 1, Marcos López-Hoyos 1, J. Gonzalo Ocejo-Vinyals 1 1Hospital Universitario Marqués de Valdecilla, Santander, Spain P240 THE ASSOCIATION OF KIR2DL4, LILRB HAPLOTYPES AND THEIR LIGAND HLA-G WITH ENDOMETRIOSIS Aleksandra Bylińska 1, Karolina Wilczyńska 2, Andrzej Wiśniewski 2, Jacek Malejczyk 3, Łukasz Milewski 3, Marta Wagner 2, Monika Jasek 2, Wanda Niepiekło-Miniewska 2, Rafał Płoski 4, Ewa Barcz 5, Piotr Roszkowski 6, Paweł Kamiński 7, Andrzej Malinowski 8, Jacek Wilczyński 9, Paweł Radwan 10, Michał Radwan 10, Piotr Kuśnierczyk 11, Izabela Nowak 11 1Politechnika Wrocławska, Wrocław, Poland - 2Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland - 3Medical University of Warsaw, Warszawa, Poland - 4Department of Medical Genetics, Centre of Biostructure Research, Warszawa, Poland - 5First Chair and Clinic of Obstetrics and Gynecology, Warszawa, Poland - 6Second Clinic of Obstetrics and Gynecology, Warszawa, Poland - 7Department of Gynecology and Gynecological Oncology, Military Medical Institute, Warszawa, Poland - 8Department of Surgical, Endoscopic and Oncologic Gynecology, Łódź, Poland - 9Department of Surgical and Oncological Gynecology, Łódź, Poland - 10Department of Reproductive Medicine, Rzgów Poland - 11Laboratory of Immunogenetics and Tissue Immunology, Wrocław, Poland P241 INCREASED FREQUENCY OF THE 14-BP INSERTION IN HLA-G Moniek H.C. Craenmehr 1, Iris Nederlof 1, Milo Cao 1, Jacqueline D.H. Anholts 1, Jos J.M. Drabbels 1, Frans H.J. Claas 1, Sebastiaan Heidt 1, Michael Eikmans 1 1LUMC, Leiden, Netherlands P242 DIAGNOSTIC TESTING OF HLA-DQ IN CELIAC DISEASE 1 1 1 1 1 1 POSTER Katarina Stingl Jankovic , Danijela Svilicic , Marija Maskalan , Marija Burek Kamenaric , Renata Zunec , Zorana Grubic 1University Hospital Centre Zagreb, Zagreb, Croatia
88 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P243 DISTINCT TYPES OF MYASTHENIA GRAVIS DIFFER BY ASSOCIATION WITH HLA CLASS II ALLELES Manuela Testi 1, Giulia Greco 2, Maria Troiano 3, Emanuele Rastelli 2, Eugenio Pompeo4, Giovanni Antonini 5, Marco Andreani 3, Roberto Massa 2 1San Camillo-Forlanini Hospital, Rome, Italy - 2Neuromuscular Unit, Rome, Italy - 3Laboratory of Immunogenetics and Transplant Biology - IME Foundation at Polyclinic of Tor Vergata, Rome, Italy - 4Thoracic Surgery Unit, Rome, Italy - 5Department NESMOS, Rome, Italy P244 THE CD147 C>G SUBSTITUTION AFFECTS SURVIVAL IN ACUTE MYELOID LEUKAEMIA Piotr Łacina 1, Aleksandra Butrym 2, Grzegorz Mazur 2, Katarzyna Bogunia-Kubik 1 1Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland - 2Wroclaw Medical University, Wrocław, Poland P245 CRITICAL APPRAISAL ON THE PROGNOSTIC VALUE OF HLA TYPING IN 8 IMMUNE- MEDIATED PATHOLOGIES BASING ON A SERIES OF META-ANALYSES Cristina Capittini 1, Marco M. Guarene 1, Chiara Rebuffi1 , Rosalia Cacciatore 1, Annalisa De Silvestri 1, Annamaria A. Pasi 1, Carmine Tinelli 1, Miryam Martinetti 1 1IRCCS Policlinico San Matteo Foundation, Pavia, Italy P246 THE ASSOCIATION OF SOLUBLE HLA-G LEVELS AND 3´ UNTRANSLATED REGION HAPLOTYPES OF THE HLA-G GENE WITH THE CLINICAL PROFILE OF EPITHELIAL OVARIAN CANCER PATIENTS REGARDING DISEASE STAGE, CIRCULATING TUMOR CELLS AND OVERALL SURVIVAL Esther Schwich 1, Sabine Kasimir-Bauer 2, Rafael T. Michita 3, Hana Guberina 4, Peter A. Horn 1, Rainer Kimmig 2, Paul Buderath 2, Vera Rebmann 1 1Transfusion Medicine, Essen, Germany - 2Gynecology and Obstetrics, Essen, Germany - 3Genetics Department, Porto Alegre, Brazil - 4Department of Nephrology, Essen, Germany P247 INFLUENCE OF CYTOKINE GENE POLYMORPHISMS ON HIV INFECTION IN NORTH INDIANS Gaurav Sharma 1, Gurvinder Kaur 1, Narinder Kumar Mehra 1, Surendra Kumar Sharma 1 1All India Institute of Medical Sciences, Delhi, India P248 ASSOCIATION OF ANXA11 AND TGFB2 GENE VARIANTS WITH PULMONARY SARCOIDOSIS IN THE GREEK POPULATION Amit Kishore 1, Angeliki Rapti 2, Katerina Sikorova 1, Veronika Zizkova 1, Maria Charikiopoulou 2, Krzysztof Rebala 3, Milan Buc 4, Martin Petrek 5 1Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic - 2General Hospital for Chest Diseases, Athens, Greece - 3Medical University of Gdañsk, Gdañsk, Poland - 4Faculty of Medicine, Comenius University, Bratislava, Slovakia - 5Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic P249 IMPLICATION OF HLA CLASS II ALLELES IN CD4/CD8 RATIO NORMALIZATION Kalliroi Tsalimalma 1, Kalliopi Adam 1, Athanasios Kontos 2, Dimitris Maltezas 2, Nikolitsa Kafassi 1 1General Hospital Athens Laiko, Athens, Greece - 2National University of Athens, Athens, Greece P250 EVALUATION OF HLA GENOTYPES IN PATIENTS REFERRED FOR CELIAC DISEASE TESTING: A TERTIARY CARE CENTER EXPERIENCE Monika Jain 1, A. Sawhney 1, I. C. Verma 1 1Sir Ganga Ram Hospital, New Delhi, India POSTER
89 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT)
P251 HLA ASSOCIATED DISEASES. WHAT SHOULD BE ANALYZED? Kirsten Kronenberg 1, Stela Radojska 1, Melanie Stoermer 1, Birgit Gathof 1 1University of Cologne, Cologne, Germany
MISCELLANEOUS P252 BETA-2-MICROGLOBULIN: A POTENTIAL BIOMARKER FOR BIPOLAR DISORDER AND SCHIZOPHRENIA? Romain Sayous 1, Céline Manier 1, Nora Hamdani 2, Alix Romier 1, Aparna Sundaresh 1, Christina Mariaselvam 1, Rémi Gadel 3, Céline Hebbache 3, Jean-Romain Richard 3, Marion Leboyer 2, Ryad Tamouza 2 1Inserm U955, Créteil, France - 2Inserm U955 / FondaMental Foundation / AP-HP, Créteil, France - 3Inserm U955 / FondaMental Foundation, Créteil, France P253 LACK OF ASSOCIATION BETWEEN THE PROTECTION FROM RED BLOOD CELL ALLOIMMUNIZATION AND HLA-CLASS II VARIANTS IN THE CZECH POPULATION Alena Maluskova 1, Frantisek Mrazek 2, Renata Kozelska 1, Jitka Rudinska 1 1Faculty Hospital Ostrava, Ostrava, Czech Republic - 2Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic P254 IMPROVEMENT OF THE PRIMARY SOURCE FOR MHC SEQUENCING DATA OF NON-HUMAN PRIMATE SPECIES (IPD-MHC NHP 2.0) Natasj G. de Groot 1, Nel Otting 1, Giuseppe Maccari 2, James Robinson 3, Steven GE. Marsh 3, John A. Hammond 2, Ronald E. Bontrop 1 1Biomedical Primate Research Centre, Rijswijk, Netherlands - 2The Pirbright Institute, Woking, United Kingdom (Great Britain) - 3Anthony Nolan Research Institute, London, United Kingdom (Great Britain) P255 AN EXTERNAL PROFICIENCY TEST (EPT) FOR SINGLE ANTIGEN FLOW BEAD (SA) ASSAYS ORGANIZED BY THE FRANCOPHONE SOCIETY FOR HISTOCOMPATIBILITY AND IMMUNOGENETICS (SFHI) Isabelle Jollet 1, Jérémy Siemowski 2, Valérie Dubois 3, Nicolas Pignon 1, Elodie Sorin 1, Nicolas Congy 4, Pascale Loiseau 2, Jean-Luc Taupin 2 1EFS Nouvelle Aquitaine, Poitiers, France - 2Hal Saint Louis, Paris, France - 3EFS Rhône-Alpes, Lyon, France - 4CHU de Toulouse - Faculté de Médecine de Purpan, Université Paul Sabatier Toulouse 3, Toulouse cedex 9, France P256 WHAT ROLE DOES IL-1BETA CYTOKINE PLAY IN INTELLECTUAL DISABILITY? Anna Aureli 1, Pierluigi Sebastiani 1, Tiziana Del Beato 1, Anna Marimpietri 2, Enzo Sechi 2, Silvia Di Loreto 1 1Institute of Translational Pharmacology, L’Aquila, Italy - 2University of L’Aquila, ASL n. 4, L’Aquila, Italy P257 THE ACCURACY OF HFE TESTING IN UK NEQAS FOR H&IS EXTERNAL QUALITY ASSESSMENT SAMPLES 2011-2017 Deborah L. Pritchard 1, M T. Rees 1 1Welsh Transplantation and Immunogenetics Laboratory, Pontyclun, United Kingdom (Great Britain) P258 HLA POLYMORPHISM AND METHOTREXATE RESPONSES IN SLOVENIAN PATIENTS WITH PSORIASIS Jasna Grzelj 1, Tanja Gmeiner 2, Pij B. Marko 3, Irena Mlinaric-Rascan 2, Sabina Kunilo-Jamnik 4, Blanka Vidan-Jeras 4 1Krka, d.d., Novo mesto, Novo mesto, Slovenia - 2University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia - 3Univeristy POSTER Medical Centre Maribor, Department of Dermatology, Maribor, Slovenia - 4Blood Transfusion Center of Slovenia, Tissue Typing Center, Ljubljana, Slovenia
90 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
P259 UK NEQAS FOR H&IS EXTERNAL QUALITY ASSESSMENT SCHEME FOR KIR GENOTYPING Deborah L. Pritchard 1, M T. Rees 1 1Welsh Transplantation and Immunogenetics Laboratory, Pontyclun, United Kingdom (Great Britain) P260 CLASSICAL HLA HAPLOTYPE DIVERSITY: A POSSIBLE LINK WITH PRO-INFLAMMATORY PROCESSES IN BIPOLAR DISORDER Ryad Tamouza 1, José Oliveira 1, Céline Manier 1, Christina Mariaselvam 1, Aparna Sundaresh 1, Rajagopal Krishnamorthy 1, Dominique Charron 1, Marion Leboyer 1 1Henri Mondor Hospital, Créteil, France P261 HD-HLA TYPING: COMPARISON BETWEEN LABTYPE SSO AND HISTO SPOT EXTEND KITS Valeria Miotti 1, Chiara Sindici 1, Donatella Londero 1, Vincenzo De Angelis 1 1ASUIUD, Udine, Italy POSTER
91 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
SPEAKERS - CHAIRS AUTHORS' INDEX 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Speakers - Chairs
Amit Ido, Rehovot - Israel Amoroso Antonio, Torino - Italy Andreani Marco, Roma - Italy Bardy Beatrice, Grenoble - France Bengtsson Mats, Uppsala - Sweden Blasczyk Rainer, Hannover - Germany Bonini Chiara, Milano - Italy Bontadini Andrea, Bologna - Italy Carcassi Carlo, Cagliari - Italy Claas Frans H.J., Leiden - The Netherlands Cozzi Emanuele, Padova - Italy Cucca Francesco, Sassari - Italy Fernández-Viña Marcelo A., Stanford - USA Fleischhauer Katharina, Essen - Germany Foeken Lydia, Leiden - The Netherlands Gourraud Pierre-Antoine, Nantes - France Gregori Silvia, MIlano - Italy Harmer Andrea, Sheffield - United Kingdom Heinemann Falko, Essen - Germany Howell Martin, Newcastle - United Kingdom Hurley Carolyn Katovich, Washington D.C - USA Ivanova Milena, Sofia - Bulgaria Keskin Derin, Boston - USA Latham Katy, London - United Kingdom Le Blanc Katarina K., Stockholm - Sweden Legendre Christophe M.F., Paris - France Löffler Markus, Tübingen - Germany Lombardi Giovanna, London - United Kingdom Lombardo Angelo, Milano - Italy Luznik Leonido, Baltimore - USA Marani Pietro Cesare, Milano - Italy Marsh Steven G.E., London - United Kingdom Martinho Antonio, Coimba - Portugal Mascaretti Luca, Trieste - Italy
94 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Mazzi Benedetta, Milano - Italy Mele Lia, Alessandria, Italy Miotti Valeria, Udine - Italy Miseferi, Reggio Calabria, Italy Morelli Adrian E., Pittsburgh - USA Mytilineos Joannis, Ulm - Germany Nanni Costa Alessandro, Roma - Italy Naumova Elissaveta, Sofia - Bulgaria Papola Franco, L’Aquilla - Italy Peacock Sarah Patricia, Cambridge - United Kingdom Piazza Antonina, Roma - Italy Querol-Giner Sergio Luis, Barcelona - Spain Quintieri Francesca, Roma, Italy Rombolà Giovanni, Firenze, Italy Roelen Dave L., Leiden - The Netherlands Sacchi Nicoletta, Genoa - Italy Sanchez-Mazas Alicia, Genève - Switzerland Sarwal Minnie M., San Francisco - USA Sawcer Stephen James, Cambridge - United Kingdom Spierings Eric, Utrecht - The Netherlands Spits Hergen, Amsterdam - The Netherlands Surendranath Vineeth, Dresden - Germany Süsal Caner, Heidelberg - Germany Tafulo Sandra, Porto - Portugal Testi Manuela, Roma - Italy Tilanus Marcel G.J., Maastricht - The Netherlands Tran Hien, Heidelberg - Germany Trowsdale John, Cambridge - United Kingdom Turner David, Edinburgh - United Kingdom Vago Luca, Milano - Italy Villard Jean, Geneva - Switzerland Voorter Christien, Maastricht - The Netherlands Wieten Lotte, Maastricht - The Netherlands
95 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Authors' index
Amirzargar, Ali...... P159 A Amokrane, Kahina...... P73 Abad-Molina, Cristina...... P21,P24,P162,P207 Amoroso, Antonio...... O8,P6,P58,P60,P65 Abatay, Figen...... P185 Anagnostouli, Maria...... P157 Abdel Fattah, Raafat...... P74,P91 Anastasiou, Aikaterini...... P8,P156 Abdrakhimova, Alena R...... P169 Andersen, Erica...... P115 Abdrakhmanova, Saniya...... P7,P61 Andersen, Menaka...... P127 Abdulle, Abdul...... P15 Anderson, Alison...... O55 Acuña-Alonzo, Víctor...... P184 Andreani, Marco...... P100,P125,P179,P243 Adam, Kalliopi...... P249 Anholts, Jacqueline D.H...... P241 Affes, Hanen...... P170 Anthias, Chloe...... O33 Aggelopoulou, Christina...... P232 Antonelli, Antonella...... O27 Ahn, Kwang Woo...... P101 Antonini, Giovanni...... P243 Akgul, Sebahat U...... P38,P39,P185 Antonova, Anzhela...... P20 Al Baz, Nabeela...... P13,P14,P80 Antovich, Zachary...... P45 Al Hadra, Bushra...... P112,P174 Apostolaki, Maria D...... P67 Al Malki, Monzr...... O6 Aptsiauri, Natalia...... P219,P225 Al Suraihi, Osama...... P14,P80 Aragon, Larraitz...... P86 Alba, Francesco...... P200,P228 Arcese, William...... O6 Albergoni, Maria Paola...... P88 Arnaiz Villena, Antonio...... P148,P158,P159,P160,P186,P187 Albers, Joris...... P130 Arnold, Marie-Luise...... P9 Alexander, Suceena...... P62 Arnold, Renate...... O37 Alfaro, Rafael...... P18,P63 Arrieta Bolaños, Esteban...... O35, P101,P184 Alizadeh, Mehdi...... P135 Artemiadis, Artemios...... P157 Alizzi, Silvia...... P6,P58 Aruldoss, Sam...... P62 Alkorta, Aitziber...... P86 Asaei, Sadaf...... P167 Allebes, W.A...... P40 Askar, Medhat...... O18,P126 Almendral, Jesus...... P42 Asouhidou, Despoina...... P156 Alonso-Rubio, Javier...... P158 Assanelli, Andrea...... O40 Al-Qadi, Rawand...... P158,P159,P160,P187 Atanasova, Valentina...... O46,P20 Alter, Idan...... O13 Atarod, Sadaf...... O38 Alvarez, Cristian M...... O44 Athanassiades, Theofilos...... P126 Alvarez, Rafael...... P133 Aureli, Anna...... P203,P231,P256 Alvarez-Lopez, Maria Rocio...... P196,P206 Auriemma, Laura...... P163 Alves, Helena...... P44 Ausín Ortega, Fernando...... P230,P235,P239 Alzate, Daniel...... O44 Autolitano, Sara...... P208,P217 Amato, Antonio...... P4 Aydin, Filiz...... P38 Ambrosi, Alessandro...... O40 Azzaro, Maria Pia...... P198 Ambruzova, Zuzana...... O30 Azzarone, Raffaella...... P163 Ameen, Reem...... P174
96 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Berki, Dorrotya...... P147 B Bernal, Monica...... P225 Baas, M.C...... P40 Berrino, Monica...... O8,P58 Bacchetta, Rosa...... P100 Bertaina, Alice...... P204 Bach, Christian...... P9 Bertinetto, Francesca E...... P60 Bade-Doeding, Christina...... O1,O56 Bertol, Bruna C...... P46 Bailly, Pascal...... P117 Bertola, Denise...... P1 Baimukasheva, Dana...... P7,P61 Bertrand, Dominique...... P68 Baker, Richard...... P41 Bessmeltsev, Stanislav...... P214 Balas, Antonio...... P155,P162 Betjes, M.G.H...... P40 Baldomero, Helen...... P103 Bhalla, Anil K...... P56 Balen, Sanja...... P66 Bhargava, Vinant...... P56 Baran, David...... P42 Bianculli, Antonio Giuseppe...... P28 Barbieri, M. Alejandro...... P176 Bibby, Louis A...... O38 Barcz, Ewa...... P229,P238,P240 Bicalho, Maria da Graça...... P46 Bardy, Beatrice...... P10 Bickhart, Derek M...... P142 Barnes, Kathleen...... O60 Biderman, Bella V...... P77 Barquera, Rodrigo...... P184 Binder, Thomas M.C...... P165,P166,P172 Barwell, Jamie...... P26 Binns-Roemer, Elisabeth...... O5 Basire, Agnes...... P2,P90 Biongiovanni, Daniela...... P65 Batarelo, Mirica...... P22 Bishara, Amal...... P189 Battarra, Mariarosa...... P125 Blaise, Didier...... O6 Battle, Richard...... P5 Blancher, Antoine...... P178 Bavetta, Rosalba...... P3,P4,P78,P132 Blancho, Gilles...... P118,P119 Bayona, Brayan...... P148 Blando, Maria...... P3,P4,P78,P132 Beaty, Terri...... O60 Blaney, Kathy...... P92,P114 Beecham, Ashley H...... O57 Blasczyk, Rainer...... O1,O3,O56 Beelen, Dietrich W...... O6,O35 Bloor, Adrian J...... O33 Beelen, Nicky...... O26 Boasi, Rachel...... P92,P114 Behzad-Behbahani, Abbas...... P216 Bochenska, Jolanta...... O29 Bellot, Sidonie...... O17 Boffini, Massimo...... P58 Bemelman, F.J...... P40 Bogacz, Anna...... P85 Benecchi, Magda...... P27 Bogunia-Kubik, Katarzyna...... O64,P16,P218,P237,P244 Benedek, Gil...... O62 Boix, Francisco...... P18,P63 Benichou, Jennifer...... O22 Bokhari, Ahmad...... P13,P14,P80 Bennasar, Florence...... P135 Bokos, Ioannis...... P67 Berardi, Gabriela...... P107 Bolarín, José M...... P196,P206 Berg, Randi...... P43 Bolcato, Vittorio...... P210 Bergamaschi, Paola...... P210 Boletis, John N...... P67 Berghella, Anna Maria...... P231 Bologov, Andrey Anatol’evich...... P83
97 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Authors' index
Bonaca, Orjeta...... P36 Budde, Klemens...... O45 Bonda, Avinash...... P98 Buderath, Paul...... P246 Bondanza, Attilio...... O27 Buhler, Stéphane...... O34,P103,P179 Bonini, Chiara...... O27 Bukowska, Alicja...... P85 Bono, Maria...... P204 Bultitude, Will P...... O33 Bontrop, Ronald E...... O12,O14,O19,O52,P178,P254 Bungener, L.B...... P40 Boorer, Linda...... P26 Bunjes, Donald...... O37 Bordasco, S...... P106 Buonomo, Oreste...... P203 Bornhauser, Martin...... O6 Burek Kamenaric, Marija...... P96,P111,P183,P193,P242 Borst, Eric...... O21 Burkitbaev, Zhandos...... P7,P61 Bos, Gerard M. J...... O25,O26,O28 Butrym, Aleksandra...... P244 Bosak, Vladimir...... P150 Bykova, Nadezhda A...... P116 Bossi, Grazia...... O51 Bylińska, Aleksandra...... P229,P240 Boswijk, Kim...... P26 Bots, M.L...... P40 Bottino, Cristina...... P204 Bottone, Antonio...... P220 C Boukla, Anna...... P8,P156 Cabrera, Teresa...... P219,P225 Bourdette, Dennis...... O62 Cacciatore, Rosalia...... P210,P245 Bouthemy, Charlene...... P35,P128 Cafarelli, Silvia...... P208,P217 Bouwmans, Evelien...... O40 Cagni, Nicoletta...... P1 Bovo, Daniela...... P88 Caillard, Sophie...... P47 Brambilla, Caterina...... P1 Caillat Zucman, Sophie...... P73 Brand-Schaaf, Simone...... P34 Cailler, Stacy...... O57 Braund, Henny...... O33 Calafiore, Valeria...... P198 Brautbar, Chaim...... P189 Calantoni, Valeria...... P191,P208,P217 Brazzelli, Valeria...... P210 Caliskan, Yasar K...... P38,P39,P185 Brezinova, Dagmar...... P109 Calýskan, Kader...... P89 Brooks, Andrew G...... O2,O4 Camisa, Barbara...... O27 Brouard, Sophie...... P118 Campillo, José A...... P196,P206 Brown, Colin J...... P134,P136,P144 Campos, Cristina...... P148,P158,P159,P160,P186,P187 Brown, Juliette...... P171 Cannavò, Antonino...... P31 Bruijnesteijn, Jesse...... O52 Cano, Pedro...... O15,P92,P114 Bruin, Helma...... P233 Canossi, Angelica...... P203,P231 Brunet, Nicolino...... P90 Cansever, Murat...... P75,P151 Bruno, Benedetto...... O6,O8 Cao, Milo...... P241 Bruno, Floriana...... P3,P4,P78,P132 Caorsi, Cristiana...... P6,P60 Bubnova, Ludmila...... P214 Capittini, Cristina...... O31,O51,P191,P245 Buc, Milan...... P248 Cappai, Luisella...... P228 Bucala, Richard...... O62 Cappuzzo, Valentina...... P3,P4,P78,P132
98 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Caputo, Flavia...... P4 Chinnadurai, Raj Kumar...... P215 Car, Helena...... P34 Chmel, Martin...... O9 Carballo, Ana...... P187 Chologitas, Evaggelos...... P29 Carcassi, Carlo...... P199,P200,P228 Chong, Winnie...... P134,P136 Cárdaba-Arranz, Mario...... P24,P162,P207 Chowdhry, Mohit...... P32 Cardillo, Massimo...... P1,P31 Christiaans, M...... P40 Carey, Sean B...... P26 Christiansen, Mette...... P30,P48 Cargou, Marine...... P128 Christine, Heylen...... P143 Caro, Jose Luis...... P155 Chronis, Theodoros...... P8 Carvalho-Oliveira, Marco...... O3 Chugreeva, Tamara P...... P169 Castrillon, Marlon...... O44 Chuva de Sousa Lopes, Susana M...... O7 Castro-Henriques, António...... P49 Ciceri, Fabio...... O6,O27,O40 Catalano, Manuela...... P124 Cidral, Ana L...... P46 Cauli, Alberto...... P199 Cipri, Selene...... P199,P200,P228 Cebeci, Egemen...... P38 Cirella, Michele...... P212,P220 Cechova, Hana...... P109 Claas, Frans H.J...... O7,O41,O43,O50,P34,P40,P53,P241 Cecuk-Jelicic, Esma...... P192 Clahsen, Marian C...... O43 Cekauskiene, Rita...... P110 Clark, Andrew...... O33 Celik, Alexander A...... O1,O56 Clark, Brendan...... P41 Cerci Gurbuz, Burcu...... P17,P213 Claus, Rainer...... O6 Cereb, Nezih...... P123,P138 Clekovic, Danijela...... P183 Cerna, Marie...... O9 Cocco, Eleonora...... P200 Cervelli, Carla...... P76,P163 Colacurcio, Vito...... P220 Cesana, Daniela...... O27 Colasante, Damiano...... P28 Cesbron, Anne...... P104,P119 Collin, Matthew...... O38 Chacko, Mary P...... P19 COLT...... P118,P119 Chalandon, Yves...... O34,P103 Concha, Ángel...... P219 Chang, Chia-Jung...... O11 Condello, Rossella...... P125 Chang, Chialing...... P72 Congeddu, Elena...... P200,P228 Chapova, Regina S...... P149,P169 Congy, Nicolas...... P255 Charfi, Aida...... P170 Connor, Andrew...... P26 Charikiopoulou, Maria...... P248 Consortium on Asthma among African-ancestry Charron, Dominique...... P260 Populations in the Americas, (CAAPA)...... O60 Chaszczewska-Markowska, Monika...... P237 Constantin, Bara...... P209 Chatzika, Georgia...... P156 Contasta, Ida Anna...... P231 Chechetkin, Aleksandr...... P214 Conticello, Etta...... P198 Chen, Qiang...... P97,P154,P182 Corongiu, Daniela...... P200 Chen-Wacker, Chen...... O3 Corti, Consuelo...... O40 Chernova, Natalia G...... P77 Coshic, Poonam...... P222 Chessa, Luchino...... P228 Cossu, Irene...... O42
99 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Authors' index
Cox, Steven T...... O53 de Groot, Natasja G...... O12,O14,O19,O52,P178,P254 Craenmehr, Moniek H.C...... P241 de Hoop, Talitha...... O21 Creary, Lisa E...... O11,O18,P155,P190 De Juan, Maria Dolores...... P86 Crespiatico, Loretta...... P1 De Sapio, Antonio...... P212 Cristian, Tieranu...... P209 De Silvestri, Annalisa...... O31,O51,P191,P245 Crivello, Pietro...... O35,P101 De Silvestro, Giustina...... P88 Crossland, Rachel E...... O38 de Vaal, Yvonne J.H...... O41 Cucca, Francesco...... P6 de Vos-Rouweler, Annemiek J. M...... O52 Cusano, Roberto...... P200,P228 Deaglio, Silvia...... O8,P6,P65 Del Beato, Tiziana...... P203,P231,P256 Delgado, Julio...... P115 Dembowski, Janusz...... P221,P223 D Demerle, Clémence...... P90 da Silva Nardi, Fabiola...... O48 Demir, Erol...... P38,P39,P59,P185 Dada, Ashraf...... P13,P14,P80 Deplano, Zareen...... P144 Dai, Ke-Zheng...... P197 Desoutter, Judith...... P188 Dametto, Ennia...... P60 Destro, Roberta...... P88 Damotte, Vincent...... O57 Devillier, Raynier...... O6 Danby, Robert...... O33,O53 Di Cristofaro, Julie...... P2,P117 Dandekar, Ravi...... O57 Di Gregorio, Giancarlo...... P231 Daniel, Dolly...... P19,P62 Di Loreto, Silvia...... P256 Dantin, Carole...... O34 Di Maio, Paolo...... P212,P220 Daoudaki, Maria...... P29 Di Raimondo, Francesco...... P198 Dapprich, Johannes...... O17,O59,O63,P176 Di, Da...... O10 Dardas, Athanasios...... P232 Diana, Daniela...... P199 Darema, Maria...... P67 Dias, Leonídio...... P49 Dassa, Sarah...... P90 Dick, Andrea...... P9 D’Auria, Rita...... P212,P220 Dickinson, Anne M...... O38 Davey, Sue...... P144 Didonna, Alessandro...... O57 Davì, Giuseppe...... P3,P4,P78 Digvijay, Kumar...... P56 David, Gaelle...... O49 Dinou, Amalia...... O54,P146 David, Vinoi G...... P62 DIVAT...... P118,P119 Davis, Kristina A...... P15 Dogan, Mustafa...... P120 Daya, Michelle...... O60 Dolff, Sebastian...... O48 Dayanand, Deo...... P42 Donadi, Eduardo A...... P46 De Angelis, Vincenzo...... P94,P261 Dongmei, Wang...... P71 De Feo, Agata...... P212 Dorak, Mehmet Tevfik...... O17,O59,O63,P120,P176 de Fijter, Hans W...... O43 D’Orsogna, Lloyd...... O50 de Fijter, J.W...... P40 Doss R, Sam A...... P19 de Groot, Nanine...... P178 Douillard, Venceslas...... P122
100 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Doxiadis, Gaby G.M...... O52,P178 Falco, Michela...... O42,P204 Doxiadis, Ilias...... P33 Falkenburg, Frederick...... O35 Drabbels, Jos J.M...... P241 Farce, Fabienne...... P68 Draghi, Eleonora...... O27 Fareq Salih, Shadallah...... P158 Dratwa, Marta...... O64,P237 Farhadi, Ali...... P216 Dubois, Valérie...... P255 Farjadian, Shirin...... P81,P216 Dubreuil, Léa...... O49 Favero, Roberta...... P88 Duhovic, Marijana...... P66 Fazio, Maria Rosaria...... P28 Duke, Jamie L...... P115 Fechtenbaum, Marie...... P188 Duquesnoy, Rene J...... P54 Felipe, Claudia R...... P69 Dutescu, Monica, I...... P209 Fenici, Lorenza...... P124 Duygu, Burcu...... P57 Fernandez Escobar, Nicolas...... P107 Dziopa, Joanna...... O36 Fernandez-Viña, Marcelo A...... O11,O18, P126,P155,P180,P190,P233 Ferraresso, Mariano...... P31 Ferrari-Lacraz, Sylvie...... O34,P103 E Ferreira, Virginia...... P90 Efimov, Grigory A...... P116 Ferreiro, Jose Javier...... P86 Ehlers, Femke...... O25,O26 Ferriola, Deborah...... P115 Eiermann, Thomas H...... P172 Field, Nell...... P15 Eikmans, Michael...... O43,P241 Figorilli, Francesco...... P228 Einsele, Hermann...... O37 Figueiredo, Constanca...... O3 Eisner, Sigal...... P50 Filkin, Sergey Y...... P116 El kaaoui El band, Jaouad...... P63 Fingerson, Stephanie...... O13 Eldem, Asli...... P17,P211 Finke, Jurgen...... O6 Elferink, Diënne...... O52 Finocchi, Martina...... O31 Elfishawi, Mohanad...... P233 Fischer, Gottfried F...... P23,P99 Elfishawi, Sally...... P91,P233 Fleischhauer, Katharina...... O6,O35,P101,P179 Ellinger, Lori...... P115 Fleva, Alexandra...... P232 Emmi, Giacomo...... O31 Florean, Lara...... P124 Emonds, Marie-Paule...... P143 Flores-A, Hilario...... P190,P201 Enriquez de Salamanca, Mercedes...... P160 Fogel, Samantha...... P15 Ertan, Serra...... P39,P185 Foster, Ruth...... P41 Espadas de Arias, Alejandro...... P31 Fotoulaki, Maria...... P232 Evgenikaki, Efthimia...... P156 Fouzas, Ioannis...... P29 Fraboulet, Sterenn...... P135 Franceschetto, Genny...... P88 Francone, Marina...... P191,P208,P217 F Franks, Thomas...... P15 Faé, Ingrid...... P23,P99 Frassati, Coralie...... P2
101 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Authors' index
Frau, Jessica...... P200 Gentner, Bernard...... O27 Froelich, Nadine...... P47 Genzano Besso, Federico...... O8 Frydecka, Irena...... P221,P223,P224,P234 Georgieva, Atanaska...... O46 Fuhrmann, Markus...... P121 Gerbase-DeLima, Maria...... P69 Fürst, Daniel...... O37, P172,P175,P177 Gesheva, Nevena...... P20 Fusco, Caterina...... P163 Giachino, Daniela F...... P65 Füssel, Monika...... P93 Giannakou, Anastasia...... P232 Fylaktou, Asimina...... P8,P29,P156 Giglio, Fabio...... O40 Gimeno, Lourdes...... P196,P206 Giral, Magali...... P118,P119 Giuliodori, Silvia...... P27 G Giuressi, Erika...... P199 Gäckler, Anja...... O48 Giustiniani, P...... P106 Gadel, Rémi...... P252 Glatt, Stephen...... P180 Gagne, Katia...... O49 Glavaš-Obrovac, Ljubica...... P168 Gaidano, Gianluca...... O8 Gmeiner, Tanja...... P258 Galaverna, F...... P106 Gnahm, Christine...... P139 Galenic, Davorka...... P22 Goeb, Vincent...... P188 Galian, Jose Antonio...... P18,P63 Goedert, James J...... O5 Gallone, Maria Rita...... P124 Goeury, Thomas...... P181 Galluccio, Tiziana...... P100 Gokarn, Anant...... P98 Gambacorta, Valentina...... O40 Gomez, Carine...... P2 Gandolfini, Ilaria...... P25 Gomez-Casado, Eduardo...... P148,P186 Gangavarapu, Sridevi...... O11,O18,P155 Gómez-Morales, Mercedes...... P219 Gaponova, Tatiana V...... P169 Gönen, Sevim...... P52 Garcia, Aracely...... P164 González Quintanilla, Vicente...... P235 Garcia-Alonso, Ana M...... P196,P206 González-Ramírez, Amanda Rocío...... P219 Gariffulin, Andrey...... P214 González, Betsy...... P190,P201 Garino, Elena...... P58 González-Escribano, María Francisca...... P24,P155 Garrido, Federico...... P219,P225 Gonzalez-Fernandez, Rafael...... P155 Gathof, Birgit...... P251 Gonzalez-Martinez, Gema...... P18 Gatin, Marine...... P68 Gopalakrishnan, Muralidhar T...... P51 Gautier Vargas, Gabriella...... P47 Góralski, Michał...... P85 Gebura, Katarzyna...... P16 Gorodezky, Clara...... P190,P201 Geerligs, Job...... P130 Gourraud, Pierre-Antoine...... O5,O60,P104,P118,P119,P122 Geffard, Estelle...... O60,P104,P118,P119,P122 Gracheva, Liudmila Alexandrovna...... P83 Gelens, M...... P40 Graczyk-Pol, Elzbieta...... O36 Gendzekhadze, Ketevan...... O6 Gragert, Loren...... O13 Geneugelijk, Kirsten...... O21 Gramatzki, Martin...... O37 Gentilini, Ivo...... P161 Grammatico, Paola...... P124
102 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Gras, Stephanie...... O50 Hammond, John A...... O19,P142,P205,P254 Grawe, Hanne...... P133 Hani, Lylia...... P215 Greco, Giulia...... P243 Harpur, Christopher M...... O2 Greco, Raffaella...... O40 Harrison, Dorothea...... P142 Green, Heftziba...... P50 Hasçuhadar, Medine...... P89 Green, Trevor...... P144 Hau, Françoise...... P68 Gregori, Silvia...... P100 Hauer, Vanessa...... P46 Griskevicius, Laimonas...... P110 Hauser, Steven L...... O57 Groeneweg, Mathijs...... O28 Haverich, Axel...... O3 Gronkowski, Mariusz...... P85 Hayhurst, James D...... O33 Grubic, Zorana...... P22,P96,P111,P179,P183,P193,P242 Hebbache, Céline...... P252 Grunz, Fabian...... O17 Heckel, Simon...... O32 Grzelj, Jasna...... P258 Heidl, Annett...... P195 Guarene, Marco...... P210,P245 Heidt, Sebastiaan...... O7,O41,P34,P40,P53,P241 Guberina, Hana...... O48,P246 Heijmans, Corrine M.C...... O12,O14 Gucyener, Emel...... P89 Heikkinen-Eloranta, Jenni...... O58 Guengoer, Tayfun...... P103 Heim, Dominik...... P103 Guerra, Sandra G...... P134,P136 Heinemann, Falko M...... O32,O48,P9 Guidicelli, Gwendaline...... P35,P128 Heinold, Andreas...... O6 Guillaume, Nicolas...... P188 Helsen, Philippe...... O14 Guimarães, Tiago...... O47 Helvacı, Özant...... P52 Gulbas, Zafer...... P89 Hemmatpour, Shahram...... P113 Gulec, Derya...... P17,P211,P227 Henderson, Lorna...... P5 Günther, Marie...... O23,P137 Hepkema, Bouke G...... P40 Guntz, Philippe...... P47,P105 Hernandez, Diana...... O53 Gupta, Anurag...... P56 Hernandez, Ennio...... P148 Gupta, Ashwani...... P56 Herrero-Mata, Maria Jose...... P155 Gwozdowicz, Slawomir...... O36,P202 Heyer, Malte...... P133 Heyn, Bianca...... P195 Hiemisch, Wiebke...... O56 Hilbrands, L.B...... P40 H Hirv, Kaimo...... P172 Haasnoot, Geert W...... O43,P53 Hitomi, Yuki...... P236 Hack, C.E...... P40 Hò, Gia-Gia T...... O1 Haddad, Rania...... P45 Hoang, Kevin...... O5 Halaburda, Kazimierz...... O36 Höffler, Klaus...... O3 Halagan, Michael...... O39,P189 Hoffmeier, Klaus...... O17 Halter, Joerg...... P103 Hofmann, Jan...... P139,P173 Hamdani, Nora...... P252 Hoitsma, A.J...... P40 Hamilton-Jones, Siobhan...... P134,P136 Hollenbach, Jill A...... O57,O60, P195
103 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Authors' index
Höllt, Thomas...... O7 Hönger, Gideon...... P54 J Honsova, Eva...... P11 Jackson, Alisa...... P129 Horinouchi, Tomoko...... P236 Jaimovich, Gregorio...... P107 Horn, Peter A...... O6,O32,O35,O48,P246 Jain, Monika...... P56,P250 Hösli, Irene...... P54 Jakovija, Arnolda...... O27 House, Justin L...... P70 Jakubauskas, Arturas...... P110 Hrabakova, Pavla...... P109 Jalali, Sedigheh...... P216 Hristova, Luisa...... O46 Jamalidoust, Marzieh...... P167 Hriz, Amal...... P170 Jaman, Sonja...... P192 Hsu, Katharine C...... O6, P101 Janin, Anne...... O38 Hudec, Michael...... O9 Janssen, Johanna W. H...... O25 Hughes, Pamela...... P41 Jansson, Katharina...... O3 Huyton, Trevor...... O1,O56 Jaramillo, Andrés...... P70 Jasek, Monika...... P240 Jaskuła, Emilia...... O29 Jeka, Sławomir...... O64,P218 I Jensen, Tore...... P127 Iandoli, Raffaele...... P220 Jesani-Hethcoat, Vasnti...... P144 Ianniello, Alice...... P65 Jia, Xiaoyuan...... P236 Iijima, Kazumoto...... P236 Jie, Wang...... P71 Illing, Patricia...... O50,O55 Jollet, Isabelle...... P255 Imbesi, Natale...... P208,P217 Joosten, Irma...... P40 Ingrassia, Francesco...... P3,P4,P78,P132 Jopek, Karol...... P85 Iniotaki, Aliki G...... P67 Juarez, Ignacio...... P148,P158,P160,P187 Innocente, Annalisa...... P1,P31 Jude, John...... P62 Iozzino, Crystal...... P,92,P114 Jue, Wang...... P182 Irure, Juan...... P12,P55 Isik, Kilicarslan...... P185 Isildak, Esra...... P89 Isobe, Noriko...... O57 K Israel, Shoshana...... P189 Kafassi, Nikolitsa...... P249 Israeli, Moshe...... P50,P95 Kalhs, Peter...... P99 Ivanova Derin, Rayna...... P73 Kamburova, Elena G...... P40 Ivanova, Milena...... P112,P174 Kamel, Hossam...... P74 Ivanova-Shivarova, Milena...... P20 Kaminska, Malgorzata...... P16 Iwaszko, Milena...... O64 Kamiński, Paweł...... P240 Kamoun, Arwa...... P170 Kanagarajah, Abbie R...... O2 Kandula, Praveen...... P42
104 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Kandur, Yaşar...... P52 Klasberg, Steffen...... O16,O23,P137 Kanga, Uma...... P222 Klein, Tirza...... P50,P95 Kannan, Sadhana...... P98 Kleina, Elizaveta...... P214 Kapsenberg, Hanneke J.M...... O7 Kleyman, Lena...... P15 Karabon, Lidia...... P221,P223,P224,P234 Klyuchnikov, Dmitry Y...... P152 Karadeniz Savran, Meltem...... P59 Kobbe, Guido...... O6 Karahan, Gonca E...... O41,P34 Köcher, Stefanie...... O17 Karakukcu, Musa...... P75 Kocyigit Ozkizilcik, Asli...... P17 Karampatakis, Theodoros...... P8,P29,P156 Koefoed-Nielsen, Pernille B...... P30,P43,P48 Kasimatis, Efstratios...... P8 Koehn, Corinna B...... P172 Kasimir-Bauer, Sabine...... P246 Kojima, Kaname...... P236 Katalinic, Natasa...... P66 Kolasiński, Michał...... P85 Katsavos, Serafeim...... P157 Kolesar, Libor...... P87,P147 Katsimpoulas, Michalis...... O54 Kolodziej, Anna...... P221,P223 Kaur, Gurvinder...... P247 Kolossa, Katarzyna...... O64,P218 Kawai, Yosuke...... P236 Konidari, Ioanna...... P176 Kedzierska, Katherine...... O2 Koning, Frits...... O7 Kekik, Cigdem...... P38,P39,P185 Kontos, Athanasios...... P249 Kelekci, Handan...... P213 Kooreman, Loes...... O26 Keles, Sevgi...... P75 Kooter, Raul...... P130 Kelsch, Reinhard...... P133,P165,P166,P172 Kopic, Kristina...... P22 Kennedy, Amy E...... P176 Koren, Daniela...... P23 Kerick, Martin...... P225 Korkmaz, Ömer...... P120 Kerkhofs, Johan...... P143 Korman, Lucyna...... O64,P237 Khamaganova, Ekaterina G...... P77,P108,P149,P169 Körper, Sixten...... P177 Khamash, Hasan A...... P70 Kose, Sukran...... P227 Khattry, Navin...... P98 Koster, Johan...... P53 Khor, Seik-Soon...... P236 Kotsimbos, Tom...... O50 Kielbinski, Marek...... P224,P234 Kouba, Noura...... P90 Kifle, Sirak...... P133 Kouniaki, Diamanto...... P126 Kilicarslan, Isin...... P39 Kountouris, Evan...... P180 Kilicaslan Ayna, Tulay...... P17,P211,P213,P227 Kovacevic Cuculic, Tjasa...... P66 Kilicoglu, Murat...... P211,P213,P227 Kovandova, Barbora...... P11 Kim, Daehwan...... O60 Kozelska, Renata...... P253 Kim, Eunsil...... P123,P138 Krajewski, Wojciech...... P221,P223 Kim, Isaac...... P45 Kramer, Cynthia S.M...... P34,P53 Kim, Sungkyu...... P123,P138 Krammes, Lena...... P165,P166,P172 Kimmig, Rainer...... P246 Krasteva, Yana...... O46 Kishore, Amit...... P248 Krezdorn, Nicolas...... O17 Kitsiou, Vasiliki...... P126 Kribben, Andreas...... O48
105 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Authors' index
Kriegova, Eva...... O30 Lange, Vinzenz ...... O6,O16,O20,O23,P93,P121, Krishnamoorthy, Rajagopal...... P215,P226,P260 P137,P139,P173,P195 Kroeger, Nicolaus...... O6 Langer, Mona...... O35 Krom, Debby G.M...... P129 Lanino, Edoardo...... P204 Kronenberg, Kirsten...... P251 Lardy, Neubury M...... O52,P40,P129 Krop, Juliette...... O41 Laserra, Anna Elisa...... P212,P220 Krydel, Michalina...... O29 Latham, Katy...... O33 Ksouda, Kamilia...... P170 Lattanzio, Roberto...... P231 Kuba, Adam...... O30 Lauridsen, Karen B...... P48 Kuchmiy, Anna A...... P116 Lazarevic, Dejan...... O6 Kuhn, Joachim...... O1 Lazar-Molnar, Eszter...... P115 Kühnel, Marc...... O3 Lazidou, Panagiota...... P232 Kulikov, Sergey M...... P108 Leboyer, Marion...... P215,P226,P252,P260 Kunilo Jamnik, Sabina...... P102,P258 Ledoux, Marie-Pierre...... P105 Kurtovic, Helena...... P66 Lee, Jar-How...... P35 Kuśnierczyk, Piotr...... P229,P238,P240 Lee, Stephanie J...... P101 Kuzmina, Larisa A...... P108 Legaz, Isabel...... P18,P63,P196,P206 Kuzminova, Elena P...... P108,P149,P169 Legrand, Nolwenn...... O49 Kuzminova, Zhanna...... P82 Lehmann, Claudia...... P33 Kwan, Patrick...... O55 Lendrem, Clare...... O38 Kwofie, Luyanda Laura...... P131 Leotta, Salvatore...... P198 Kyriacou, Monica...... P144 Levi, Chen-li...... P95 Levinson, Douglas...... P180 Li, Chi-Cheng...... P72 Li, Dongmei...... P71,P153 Li, Jiang...... P182 L Li, Mengdan...... P97,P154 Lachmann, Nils...... O24,O45 Li, Ming...... P143,P180 Łacina, Piotr...... P244 Li, Raymond...... P45 Lai, Sara...... P200,P228 Li, Wei...... P153 Laivuori, Hannele...... O58 Li, Xingjie...... P154 Lamanna, Roberta...... P27 Libri, Giuseppe...... P217 Lambeck, A.J...... P40 Lidija, Orlic...... P66 Landgraf, Ramona...... P33 Lima, Bruno A...... P44 Lane, William J...... P45 Limou, Sophie...... O5,O60,P104,P118,P119,P122 Lang, Kathrin...... O16,O20,O23,P137,P139,P173 Lin, Chuen-Ying...... P72 Lange, Andrzej...... O29 Lin, Jie...... O4 Lange, Janusz...... O29 Lindemann, Monika...... O32 Lange, Kathrin...... O6 Lioure, Bruno...... P105 Lange, Leslie...... O60 Litniski, Alexandra...... O39
106 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Littera, Roberto...... P199,P228 Madrigal, J. Alejandro...... O33,O53,P184 Liu, Dongjing...... P153 Madrigal-Sánchez, Juan José...... P184 Liu, Feiyun...... P72 Magalhães, Maria Conceição...... O47 Liu, Tommy...... P143 Maggiore, Umberto...... P25 Lizée, Antoine...... O60 Magistroni, Paola...... P58,P60,P65 Llorente, Santiago...... P18,P63 Magnan, Antoine...... P118,P119 Llull, Cintia...... P107 Mah, Helen...... P45 Lobato, Luísa...... P49 Mahaweni, Niken M...... O25,O28 Lobo Pereira, Francisco...... O8 Mahfoudh, Nadia...... P170 Locatelli, Franco...... P106,P204 Maiers, Martin...... O13,O39,P189 Lochmann, Evi...... P161 Maisto, Giovanna...... P163 Loi, Valentina...... P200,P228 Majorana, Maria...... P212 Loiseau, Pascale...... P73,P255 Makni, Hafedh...... P170 Lokki, A. Inkeri...... O58 Makroo, RN...... P32 Lokki, Marja-Liisa...... O58,O61 Makrovasili, Fani...... P29,P156 Lombardo, Angelo...... O27 Makushik, Kelsey...... P15 Londero, Donatella...... P94,P261 Malejczyk, Jacek...... P240 Longa, Lucia...... P76 Malestein, Remco...... P145 Longhi, Elena...... P1 Malheiro, Jorge...... P49 Lopasso, Aurélie...... P90,P117 Malik, Manish...... P56 López-Hoyos, Marcos...... P12,P55,P230,P239 Malinowski, Andrzej...... P229,P238,P240 Lorenzi, Marco...... P76 Mallempati, Kalyan C...... O11,O18,P155 Loundou, Anderson...... P2 Mallis, Panagiotis...... O54 Louzoun, Yoram...... O13,O22,O39 Malmberg, Karl-Johan...... O2 Lu, Joseph...... P129 Maltezas, Dimitris...... P249 Luiken, Bram...... P129,P133 Maluskova, Alena...... P253 Lukanov, Tsvetelin...... O46,P112,P174 Malvezzi, Paolo...... P10 Lupo Stanghellini, Maria Teresa...... O6,O40 Manetta, Sara...... O6 Lyonnet, Luc...... P2 Manfreda, Annarita...... P28 Maniangou, Bercelin...... O49 Manier, Céline...... P226,P252,P260 Mannarino, Savina...... O51 M Mansouri, Marzieh...... P81 Mabrok, Mazen...... P26 Manzo, Antonella...... P212,P220 Maccari, Giuseppe...... O19,P254 Marcenò, Raimondo...... P3,P4,P78,P132 Macchiagodena, Mario...... P1 Marchesani, Marja...... O61 Mack, Steven J...... O18,O61 Marchionni, Luigi...... O8 MacKinnon, Stephen...... O33 Marczi, Saška...... P168 Madbouly, Abeer...... O39,P189 Marget, Matthias...... P165 Maddi, Roberta...... P200,P228 Mariaselvam, Christina Mary...... P226 ,P252,P260
107 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Authors' index
Marimpietri, Anna...... P256 Melchiorre, Tiziana...... P58 Marin, Luis...... P155 Melis, Cristina...... P200 Marinovic, Ivanka...... P192 Melis, Maurizio...... P200,P228 Marko, Pij B...... P258 Melista, Efi...... P87,P147 Markopoulou, Maria...... P232 Méndez García, Míguela...... P219 Marks, David I...... O33 Mengozzi, Giulio...... P65 Marrari, Marilyn...... P54 Mercurio, Manuel...... P217 Marsh, Steven G.E...... O19,O33, P184, P254 Merli, P...... P106 Martin, Javier...... P225 Merli, Roberta...... P25,P27 Martinetti, Miryam...... O51,P245 Messa, Piergiorgio...... P31 Martinez, Natalija...... P22 Metzing, Maximilian...... O35 Martinez-Garcia, Pedro...... P63 Meulenberg, Pieter...... P130 Martinez-Gonzalez, Gema...... P63 Meurer, Thuja...... O35 Martino, Enrica...... P198 Meyer, Pieter W...... P131 Martinovic-Kaliterna, Duska...... P192 Michalopoulos, Efstathios...... O54,P146 Martín-Villa, José Manuel..... P148,P158,P159,P160,P186,P187 Michita, Rafael T...... P246 Martynkevich, Irina...... P214 Middleton, Derek...... P179 Marulli, Giuseppe...... P231 Mifsud, Nicole...... O50,O55 Maschan, Alexei...... P84 Migliara, Alessandro...... O27 Maschan, Michael...... P82,P84 Mignot, Emmanuel...... P180 Maskalan, Marija...... P96,P111,P183,P193,P242 Mihai, Bojinca...... P209 Massa, Roberto...... P243 Mihaylova, Anastasya...... O46,P20 Massalski, Carolin...... P173 Mihaylova, Snezhina...... O46 Masson, Dominique...... P10 Mika-Witkowska, Renata...... O36 Massouridi-Levrat, Stravoula...... P103 Mikulic, Mirta...... P111 Maszko-Wodzinska, Iwona...... O29 Milewski, Łukasz...... P240 Matern, Benedict M...... P57 Mindrinos, Michael...... P180 Mathew, Libin...... P98 Mine, Karina L...... P69 Mathias, Rasika...... O60 Mingari, Maria Cristina...... O42 Mathow, Daniel...... P133 Minguela, Alfredo...... P18,P63,P196,P206 Mäurer, André P...... P137,P173 Miotti, Valeria...... P94,P261 Mayor, Neema P...... O33 Mircea, Diculescu...... P209 Mazur, Grzegorz...... P244 Mishra, Manoj...... P32 Mazzoco, Michela...... P174 Misra, Maneesh K...... O57 Mazzola, Gina A...... P58 Mistretta, Serena...... P3,P4,P78,P132 McCauley, Jacob L...... O57,O59,P120,P176 Mittal, Siddharth...... P19,P62 Medina-Pestana, José O...... P69 Mlinaric-Rascan, Irena...... P258 Meertens, Christel M.H...... P57 Mohapatra, Anjali...... P62 Mehra, Narinder Kumar...... P247 Mohty, Mohamad...... O6 Meintjes, Peter...... P147 Molenbroeck, Stefan...... O28
108 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Møller, Bjarne K...... P30 Nair, Gayathri...... P103 Monos, Dimitri...... P115 Namayandeh, Mandana...... P167 Montanari, M...... P106 Nane, Ismet...... P59 Montanič, Sendi...... P102 Naper, Christian...... P197 Montero-Martin, Gonzalo...... O11,P155 Nareiko, Maria V...... P77 Montesu, Maria Antonietta...... P199 Nasilowska-Adamska, Barbara...... O36 Montini, Eugenio...... O27 Naumova, Elissaveta...... O46,P20,P112,P174 Monzón, David...... P86 Navaretti, Elena...... P60 Mor, Eytan...... P50 Navarrete, Cristina V...... P134,P136 Morath, Christian...... O44 Nederlof, Iris...... P241 Moreira-Espinoza, María José...... P184 Nedilakova, Antoaneta...... P112,P174 Moretta, Alessandro...... P204 Negi, Vir Singh...... P215,P226 Moretta, Lorenzo...... O42,P204 Nelson, George...... O5 Morikone, Pablo...... P107 Nelson, Lora J...... P70 Moscetti, Alessandra...... P124 Nesher, Eviatar...... P50 Moschini, Pamela M...... P6,P58,P60,P65 Nestorowicz, Klaudia...... O36,P202 Mossallam, Ghada...... P74,P233 Neuchel, Christine...... O37,P172,P175,P177 Mounsey, Katherine...... P41 Nguyen, Thi H.O...... O2 Mourão, Tuíla B...... P69 Nickman, Hosein...... P159 Mourya, Manish...... P222 Nicoloso, Grazia...... P103 Moussa, Omar...... P15 Niederwieser, Dietger...... O37 Moya-Quiles, Maria R...... P18,P63,P155,P196,P206 Niemann, Matthias...... O24,O45,P54 Mratinovic-Mikulandra, Jela...... P192 Nieminen, Markku S...... O61 Mrazek, Frantisek...... O30,P253 Niepiekło-Miniewska, Wanda...... P16,P240 Müberra, Ahci...... O6 Nieszporek, Artur...... P16 Mulder, Wietse...... O40 Nieto, Antonio...... P21 Mulgaonkar, Shamkant...... P42 Nieto, Jorge...... P158,P160,P187 Munguia, Andrea...... P190,P201 Nikbin, Behrouz...... P159 Muñiz, Ester...... P148,P158,P159,P160,P186,P187 Nikolaidou, Vasiliki...... P8 Muro, Manuel...... P18,P63,P155,P196,P206 Niokou, Dimitra...... P144 Murru, Roberta...... P200 Nocco, Angela...... P1 Mytilineos, Joannis...... O37,P172,P175,P177 Nocito-Colón, Mercedes...... P207 Nong, Thoa...... P35 Norden, Jean...... O38 Norman, Paul J...... P195 N Notaro, Ilaria...... P65 Nagasaki, Masao...... P236 Novelli, Giorgio...... P203 Nagler, Arnon...... O6 Nowak, Izabela...... P229,P238,P240 Nagy, Marion...... O17 Nowak, Jacek...... O36,P202 Nagy, Nora...... P147 Nozu, Kandai...... P236
109 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Authors' index
Nunes, José Manuel...... O10, P103,P179,P181 Ozel, Leman...... P89 Nurmohamed, A...... P40 Ozkizilcik Kocyigit, Asli...... P211,P213 Ozluk, Yasemin...... P39,P185 Ozzella, Giuseppina...... P28 O Ocejo-Vinyals, J. Gonzalo...... P155,P230,P235,P239 Offner, Halina...... O62 P Oguz Savran, Fatma...... P38,P39,P59,P185 Padros, Karin...... P79,P107 Oksenberg, Jorge R...... O57,O62 Pagliuca, Antonio...... O33 Olagne, Jerôme...... P47 Pakos, Helena...... O29 Olbromski, Krzysztof...... P85 Palacio-Gruber, Jose...... P148,P158,P159,P160,P186,P187 Olieslagers, Timo I...... O28 Palfi, Biserka...... P22 Olivares, Ivan Rivas...... O28 Palumbo, Carmela...... P217 Olivares, Nerea...... P86 Papachristou, Marianthi...... P8,P29 Olivas-Martínez, Israel...... P24 Papagianni, Aikaterini...... P8 Oliveira, Giacomo...... O27 Papapanagiotou, Aggeliki...... O54 Oliveira, Jeffrey...... O12 Papola, Franco...... P76,P163 Oliveira, José Gerardo...... O47,P37,P215,P260 Parakh, Shilpa...... P129 Olivia, Popa M...... P209 Paredes-Carias, Edel...... P184 Ollila, Hanna...... P180 Parga Lozano, Carlos H...... P164 Omae, Yosuke...... P236 Parisi, Marina...... P198 Onali, Simona...... P228 Parissiadis, Anne...... P47,P105 Onnis, Giuliana...... P199 Parkinson, Andrea...... P15 Onozawa, Masahiro...... O6 Parlavecchio, C...... P106 Ontañón-Rodríguez, Jesús...... P207 Parolini, Riccardo...... O40 Opelz, Gerhard...... O44 Parovichnikova, Elena N...... P108 Orchard, Kim...... P113 Parren, Paul W.H.I...... P34 Orduña-Domingo, Antonio...... P162,P207 Partyka, Anna...... P221,P223,P224,P234 O’Reilly, Steven...... O38 Pasi, Annamaria A...... O51,P210,P245 Órlich-Pérez, Priscilla...... P184 Paskalev, Emil...... O46 Orrù, Nicola...... P199 Passamonti, Serena Maria...... P31 Orrù, Sandro...... P199,P228 Passweg, Jakob...... P103 Osoegawa, Kazutoyo...... O11,O18,P126 Pasvoski, Oren...... P95 Oterino Durán, Agustín...... P235 Patiroglu, Turkan...... P75,P151 Otten, H.G...... P40 Paul, Pascale...... P2 Otting, Nel...... O19,O52,P178,P254 Pavlatova, Lucie...... P109 Ottonello, Selene...... O42 Pavlova, Anastasia...... P214 Özbek, Umut...... P176 Pavlova, Irina...... P214 Ozcan, Alper...... P75 Pawliczak, Daria...... O36
110 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Pearce, Kim F...... O38 Pizzochero, Cinzia...... P210 Peccatori, Jacopo...... O6,O40 Plaisier, L...... P40 Pedersen, Alice P...... P127 Planelles, Dolores...... P155 Pegova, Kristyna...... P109 Plesec, Eva...... P36 Peitsch, Cory...... P15 Płoski, Rafał...... P238,P240 Pelardy, Matthieu...... P2 Poggi, Elvira...... P28 Pellegrini, Patrizia...... P231 Poirier, Nicolas...... P178 Pende, Daniela...... P204 Poles, Ann...... P115 Penickova, Sona...... P150 Poles, Anthony...... P26 Penning, Maarten T...... P129,P130,P141,P145 Poli, Francesca...... P31 Penta de Vera Aragona, Roberta...... P163 Pompeo, Eugenio...... P243 Perea, Francisco...... P219,P225 Pons, Jose A...... P18 Pérez Pereda, Sara...... P235 Porcella, Rita...... P200,P228 Pérez-Escobar, Oscar A...... O17 Potter, Michael N...... O33 Perola, Markus...... O61 Potter, Victoria T...... O33 Perotti, Laura...... P76 Poyraz, Aykut...... P151 Perrone, Francesco...... P60 Prerovska, Renata...... P109 Perrot, Eric...... P135 Pristanskova, Ekaterina Andreevna...... P83 Perry, Julia...... O33 Pritchard, Deborah L...... P140,P257,P259 Peter, Wolfgang...... P165,P166,P172 Profaizer, Tracie...... P115 Petrek, Martin...... O30,P168,P248 Prucca, Maristella...... P76 Petrillo, Marika...... P212,P220 Pruschke, Jens...... P139,P173 Petrova, Larisa Vladimirovna...... P83 Puchala, Marta...... P218 Phieler, Julia...... P121 Puglisi, Fabrizio...... P198 Piazza, Antonina...... P28 Punatar, Sachin...... P98 Piazza, Bruna...... P3 Purcell, Anthony...... O50,O55 Picard, Christophe...... P2,P90,P117,P135 Pymm, Philip...... O4 Picardi, Alessandra...... O6 Piccolo, Adriana...... P210 Pidala, Joseph...... P101 Pietra, Gabriella...... O2,O42 Q Pignon, Nicolas...... P255 Qiu, Yan...... P153 Pilunov, Artem M...... P116 Quin, Lyudmila...... P112 Pinana, Jose L...... O6 Pinelli, David...... P51 Pini, Massimo...... O6 Pino-Yanes, Maria...... O60 R Pinto, R. M...... P106 Rabbi, Sikder N.I...... P165 Piovano, Federica...... P76 Rachamimov, Ruth...... P50 Pitzalis, Maristella...... P6 Radojska, Stela...... P251
111 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Authors' index
Radwan, Michał...... P238,P240 Rodriguez, Joshua M...... P45 Radwan, Paweł...... P238,P240 Rodriguez, Maria Beatriz...... P79,P107 Rafaels, Nicholas...... O60 Roelen, Dave L...... O41,P34,P40,P53 Rafiei-Dehbidi, Gholam-Reza...... P216 Rogatko-Koros, Marta...... O36 Ragatzu, Paola...... P199,P200,P228 Rojewski, Markus...... P177 Raida, Ludek...... O30 Romagnoli, Renato...... P60 Rajadhyaksha, Sunil...... P98 Romaniuk, Dmitry S...... P116 Rajkumar, Ravi Philip...... P215,P226 Romano, Alessandra...... P198 Ralazamahaleo, Mamy...... P35,P128 Romeo, Giuseppa...... P191,P208,P217 Ramilyeva, Indira...... P7,P61 Romier, Alix...... P252 Ramirez, Maria...... P15 Roncarolo, Maria Grazia...... P100 Ramirez, Yasmill...... P114 Roozendaal, C...... P40 Ramondetta, Miriam...... P1 Rossjohn, Jamie...... O4 Rampim, Gisele F...... P69 Rosso, Claudia Maria...... P6 Rampoldi, Luca...... P65 Rostaing, Lionel...... P10 Ramzi, Mani...... P81 Roszkowski, Piotr...... P240 Rana, Devinder S...... P56 Rotar, Katja...... P36 Rao, Prakash...... P42 Roth, Tobias...... P165,P166,P172 Rapti, Angeliki...... P248 Rothe, Jessica...... O17 Rastelli, Emanuele...... P243 Rowntree, Louise...... O50 Ratajczak, Philippe...... O38 Rozemuller, Erik H...... P130,P141,P145,P233 Raykina, Elena...... P82,P84 Ruczinski, Ingo...... O60 Rebala, Krzysztof...... P248 Rudd, Stephen...... O17 Rebmann, Vera...... O48,P246 Rudinska, Jitka...... P253 Rebuffi, Chiara...... P245 Ruiz-Cabello, Francisco...... P219,P225 Rees, M.T...... P140,P257,P259 Ruiz-del-Valle, Valentín...... P186 Reinders, Marlies E.J...... O43 Ruiz-San Millán, Juan Carlos...... P12 Retiere, Christelle...... O49 Russell, Nigel H...... O33 Rey, Diego...... P159 Russnak, Roland...... P45 Reynaud-Gaubert, Martine...... P2 Ruzius, Frans-Paul...... P130 Richard, Jean-Romain...... P252 Ryu, Jaejun...... P138 Richardson, Debbie...... P113 Ridgley, Rose M...... P70 Riesco, Laura...... P12,P55,P230,P235,P239 Rihova, Adela...... O9 S Rijnaard, Hans J.H.A...... O12 Sacchi, Nicoletta...... P174 Ripaldi, Mimmo...... P163 Saduakas, Zhazira...... P7,P61 Robinson, James...... O19,O33,P254 Sage, Deborah A...... P113 Rocchi, Lorenzo...... P60 Saglio, Giuseppe...... O8 Rodrigo, Emilio...... P12,P55 Saif, Imran S...... P26
112 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Saladino, Rita E...... P191,P208,P217 Schetelig, Johannes...... P93 Salazar-Sánchez, Lizbeth...... P184 Schirru, Lucia...... P200 Sali, Vera...... P194 Schmidt, Alexander H. Salizzoni, Mauro...... P60 ...... O6,O16,O20,O23,P93,P121,P137,P139,P173,P195 Salomaa, Veikko...... O61 Schneiderova, Petra...... O30 Salvadori, Filomena...... P217 Schoene, Bianca...... P139 Salzberg, Steven...... O60 Schöfl, Gerhard...... O16,O20,O23,P93,P121,P137 Samardžija, Marina...... P168 Schoina, Maria...... P8 Sampaio-Norton, Susana...... O47,P37 Schöne, Bianca...... P121 San Segundo, David...... P12,P55 Schönemann, Constanze...... O45 Sánchez, Guadalupe...... P201 Schrezenmeier, Hubert...... O37,P175,P177 Sanchez-Garcia, Florentino...... P155 Schwartz, John C...... P142,P205 Sanchez-Gordo, Francisco...... P155 Schwich, Esther...... P246 Sanchez-Mazas, Alicia...... O10,P103,P179,P181 Sconocchia, Giuseppe...... P203 Sánchez-Palencia, Abel...... P219,P225 Sebastiani, Pierluigi...... P256 Sanders, J.S.F...... P40 Sechi, Enzo...... P256 Santaniello, Adam...... O57 Secinaro, Enzo...... P231 Santaniello, Francesco...... O27 Sedzimirska, Mariola...... O29 Sanz, Guillermo...... O6 Seelen, M.A.J...... P40 Sanz, Jaimie...... O6 Seitz, Adrienne...... P41 Sarkar, Subhashis...... O25 Sekerkova, Zuzana...... P11 Sathananthan, Thusa...... P144 Sela-Navon, Michal...... P95 Satta, Rosanna...... P199 Semana, Gilbert...... P135 Saudemont, Aurore...... O53 Senev, Aleksandar...... P143 Saunders, Philippa M...... O4 Senturk Ciftci, Hayriye...... P59 Sauter, Jürgen...... P139,P173,P195 Serra, Anna...... O8 Savchenko, Valeriy G...... P77,P108,P169 Serra, Maria...... P200,P228 Savran Oguz, Fatma...... P89 Serrano-Vela, Ignacio...... P186 Sawhney, A...... P250 Serventi Seiwerth, Ranka...... P111 Sayno, Jex-Ray...... O33 Seshadri, Vijayaragavan...... P123,P138 Sayous, Romain...... P252 Sever, Mehmet S...... P39,P185 Sbarsi, Ilaria...... P210 Sgobba, Valentina...... P27 Schäfer, Marco...... P165,P166,P172 Shan, Xiaoyan...... P71 Schaffer, Brian...... O6 Shargian, Liat...... P95 Schall, Cynthia...... P15 Sharma, Gaurav...... P247 Schanz, Urs...... P103 Sharma, Surendra Kumar...... P247 Schaub, Stefan...... P54 Sharma, Vandana...... P32 Schauss, Debra...... P15 Shaw, Bronwen E...... O33,P101,P184 Schefzyk, Daniel...... P139,P173 Sheetikov, Savely A...... P116 Scherdel, Pauline...... P118,P119 Shivarov, Velizar...... P174
113 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Authors' index
Shomo, Akemi...... P236 Spierings, Eric...... O21,O24,O45,P40 Shragina, Olga...... P82,P84 Spriewald, Bernd M...... P9 Sidira, Evangelia...... P156 Spruyt-Gerritse, Marijke J...... O43 Siebert, Nicole...... P166 Spyropoulou-Vlachou, Maria...... O54,P146 Siemowski, Jérémy...... P255 Stacey, Sara...... P26 Siffnerova, Vera...... P87 Staeck, Oliver...... O24,O45 Sikorova, Katerina...... P168,P248 Stankova, Martina...... P109 Silhova, Elena...... O9 Stavropoulos-Giokas, Catherine...... O54,P146 Silva, Selma D...... P98 Steckel, Nina K...... O6 Silvera, Carlos...... P148 Štefanić, Mario...... P168 Silvestri, Elena...... O31 Stein, Jeremy E...... P184 Silvy, Monique...... P117 Stein, Jerry...... P95 Simac Susanj, Ines...... P66 Stempelmann, Karin...... O6 Simmons, Gregory...... P15 Steri, Maristella...... P6 Simon, Sophie...... P90 Stevens, Jeroen M.G...... O14 Simper, Gwendolin S...... O1,O56 Stingl Jankovic, Katarina...... P96,P111,P183,P193,P242 Sindici, Chiara...... P261 Stoermer, Melanie...... P251 Singh, Mandhata...... P32 Stoll, Scott...... P70 Singh, Meenakshi...... P98 Stölzel, Friedrich...... O6 Singh, Sandeep K...... O59,O63,P176 Stranges, Alessia...... P217 Sinisalo, Juha...... O58,O61 Strano, Aurora...... P88 Sinopoli, Silvia...... P28 Stratta, Piero...... O8 Sioli, Viviana...... P1 Studer-Bettens, Florence...... O34 Siorenta, Alexandra A...... P67 Stupniko, Aleksei...... O8 Skalisz, Hanna...... P85 Sudarikov, Andrey B...... P77 Skorobogatova, Elena Vladimirovna...... P83 Sullivan, Lucy C...... O2,O42 Skoumi, Dimitra A...... P67 Sundaresh, Aparna...... P215,P226,P252,P260 Slavcev, Antonij...... P11 Sürel, Ö. Orkun...... P120 Smith, Tim P.L...... P142 Surendranath, Vineeth...... O20,P121 Smits, Marjolein...... O26 Süsal, Caner...... O44 Soonawala, Darius...... O43 Suslova, Tatiana A...... P152 Sorin, Elodie...... P255 Svetec, Magdalena...... P22 Sortino, Grazia...... P198 Svilicic, Danijela...... P193,P242 Sotiriadou, Fotini...... P232 Swelsen, Wendy T...... O52,P40,P129 Sowiński, Mateusz...... P85 Świerkot, Jerzy...... O64,P218,P237 Söylemezoğlu, Oğuz...... P52 Szczepinski, Andrzej...... O36 Soyoz, Mustafa...... P17,P211,P213,P227 Szlendak, Urszula...... O36,P202 Sözen, Hakan...... P52 Szydlo, Richard M...... O33 Spano, Lucia...... P28 Spellman, Stephen...... P101
114 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Topcu, Sinem...... P213 T Torgerson, Dara...... O60 Tafulo, Sandra...... P49 Toriello Suárez, María...... P235 Talal, Chatila...... P75 Toriello, Mario...... P163 Tambe, Manisha...... P98 Torres, Franklin...... P164 Tambur, Anat R...... P51 Toscanini, Ulises...... P79,P107 Tamouza, Ryad...... P215,P226,P252,P260 Toscano, Sebastiana...... P198 Tandoi, Francesco...... P60 Tranquilli, Stefania...... P200 Tandon, Nikhil...... P222 Trilling, Mirko...... O48 Tang, Ruoping...... O6 Troiano, Maria...... P243 Tarassi, Katerina...... P126 Trojok, Peter...... P166 Taub, Margaret...... O60 Trucas, Marcello...... P228 Taupin, Jean-Luc...... P35,P255 Trunecka, Pavel...... P11 Tavarozzi, Franco...... O33 Trusova, Larisa M...... P152 Tavkin, Elena...... P129 Tsalimalma, Kalliroi...... P249 Tedeschi, Sara...... P25 Tsamadou, Chrysanthi...... O37,P175,P177 Tedesco-Silva, Hélio...... P69 Tsirogianni, Alexandra...... P126 Tefik, Tzevat...... P59 Tsuang, Ming...... P180 Temurhan, Sonay...... P38,P39,P185 Turazzi, Nice...... O27 Ten Berge, I.J.M...... P40 Turganbekova, Aida...... P7,P61 Teshima, Takanori...... O6 Turiano, Francesco...... P208 Testa, Giuseppe...... P125 Turkmen, Aydin...... P39,P59,P185 Testi, Manuela...... P124,P125,P243 Turnbull, Angus...... P5 Tetar, Gayatri C...... P129 Turner, David M...... P5 Thakur, Yogita...... P32 Turner, Thomas R...... O33 Thomas, Pascal...... P2 Tyumina, Olga V...... P152 Thomson, Kirsty J...... O33 Tielens, Kaat...... O12 Tieranu, Ioana...... P209 Tiercy, Jean-Marie...... P103 U Tilanus, Marcel G.J...... O25,O26 O28,P40,P57 Uçan, Gulsah...... P75 Tinelli, Carmine...... O31,O51,P191,P245 Ulman, Maayan...... O6 Tissot, Adrien...... P118,P119 Unal, Ekrem...... P75 Todaro, Sonia...... O6 Uyar-Mercankaya, Merve...... O7 Toffalori, Cristina...... O6,O40 Tokić, Stana...... P168 Tokunaga, Katsushi...... P236 Tomaszewska, Agnieszka...... O36 V Tomkiewicz, Anna...... P221,P223 Vaage, John Torgils...... P197 Tomoya Michita, Rafael...... O48 Vago, Luca...... O6,O27,O40
115 25th Annual Meeting nd EUROPEAN IMMUNOGENETICS ART AND SCIENCE: THE EVOLVING PICTURE of the Italian Society AND HISTOCOMPATIBILITY OF IMMUNOGENETICS for Immunogenetics and Transplantation CONFERENCE VENICE LIDO, MAY 9-12, 2018 JOINT CONFERENCE EFI-AIBT 32 Biology (AIBT) Authors' index
Valatkaite-Rakstiene, Beatrice...... P110 Verma, I. C...... P56,P250 Valencia, Miriam...... P201 Verneris, Michael R...... P101 Valentini, Maria Donatella...... P228 Verosimile, Mattia...... P220 Valhova, Sarka...... P11 Verzijl, Cristy...... O12 van Balen, Peter...... O35 Viard, Thierry...... P45 van de Pasch, Loes A.L...... P141,P145,P233 Vicario, Jose Luis...... P155,P162 van den Heuvel, Heleen...... O50 Vidan-Jeras, Blanka...... P36,P102,P258 van der Boog, P.J.M...... P40 Viken, Marte K...... P127 van der Hoorn, Marie-Louise P...... O7 Vilches, Carlos...... P155 van der Meer, A...... P40 Vilches-Moreno, Miriam...... P21,P24,P207 van der Pant, K.A.M.I...... P40 Villard, Jean...... O34,P81,P103 van der Weerd, N.C...... P40 Vince, Nicolas...... O5,O60,P104,P118,P119,P122 Van der Wiel, Marit K.H...... O52,P178 Vinti, Valentina...... P4 van der Zwan, Anita...... O7 Visentin, Jonathan...... P35,P128 van Deutekom, Hanneke W.M...... P130,P141 Vitale, Antonio...... P212 van Duijnhoven, E...... P40 Vittoraki, Angeliki G...... P67 van Gelder, Michel...... O26 Vivian, Julian P...... O4 van Ham, Karin...... P141 Vogel, Benjamin...... P133 van Heck, Michelle...... P145 Voloshin, Sergey...... P214 van Ittersum, F...... P40 Volpin, Monica...... O27 Van Kooten, Cees...... P34 Voorter, Christina E.M...... O28,P40,P57 Van Laar, Jacob M...... O38 Vrana, Milena...... P87 van Reekum, F...... P40 Vrani, Vasiliki...... P146 Van Sandt, Vicky...... P143 van Unen, Vincent...... O7 van Wageningen, Sake...... P129,P133 van Zuilen, A.D...... P40 W Vandenbark, Arthur A...... O62 Wagner, Eva...... O37 Vanegas-Padilla, Yondra...... P184 Wagner, Marta...... P240 Varughese, Santosh...... P62 Walencik, Alexandre...... O60,P104,P119,P135 Vasyukov, Konstantin V...... P169 Wang, Hai-Lin...... P101 Vavilov, Mikhail N...... P152 Wang, Jue...... P97 Vayntrub, Tamara...... O11,P155 Wang, Xiao-nong...... O38 Vecchiato, Cinzia...... P161 Warnecke, Gregor...... O3 Vega, Maria Igea...... P3,P4,P78,P132 Waterhouse, Miguel...... O6 Velier, Mélanie...... P90 Watson, Harold...... O60 Vendelbosch, Sanne...... P141 Wehmeier, Caroline...... O41 Verduci, Anna Maria...... P208,P217 Wenda, Sabine...... P23,P99 Verhaar, M.C...... P40 Wendel, Jennifer...... P92,P114 Verite, Franck...... P135 Widjaja, Jacqueline M.L...... O2,O4
116 25th Annual Meeting of the Italian Society for Immunogenetics
JOINT CONFERENCE EFI-AIBT and Transplantation Biology (AIBT)
Wielińska, Joanna...... P237 Yazici, Halil...... P39,P185 Wieten, Lotte...... O25,O26,O28,P40 Yeshurun, Moshe...... P95 Wiland, Piotr...... O64 Yuanyuan, Jing...... P71 Wilczyńska, Karolina...... P229,P238,P240 Yuen, Vivian...... P45 Wilczyński, Jacek...... P229,P238,P240 Wilde, Benjamin...... O32,O48 Willem, Catherine...... O49 Williams, Kevin...... P115 Z Williams, Timothy...... P15 Zakharova, Viktoria...... P82,P84 Willis, Amanda...... P126 Zaky, Khaled Abdelmonen...... P233 Wilson, James...... O60 Zanelli, Paola F...... P25,P27 Wilson, Marie C...... O33 Zanetti, Adele...... P25 Winkler, Cheryl...... O5 Zare, Maryam...... P167 Wiśniewski, Andrzej...... P229,P240 Zarras, Charalampos...... P29 Wisse, B.W...... P40 Zavvos, Georgios...... P67 Witkowska, Agnieszka...... O36 Zdrojowy, Romuald...... P221,P223 Witzke, Oliver...... O32,O48 Zecca, Marco...... P204 Wojcik, Michal...... O36 Zeghal, Khaled...... P170 Worah, Kuntal...... O23,P137 Zeier, Martin...... O44 Woszczyk, Dariusz...... P224,P234 Zhang, Yi...... P153 Wróblewska-Kabba, Sylwia...... P85 Zhongmei, Wang...... P71 Wu, Tao Beijing...... P153 Zhunus, Perizat...... P7,P61 Wysoczańska, Barbara...... O64 ,P218,P237 Ziyaeyan, Mazyar...... P167 Zizkova, Radka...... P109 Žižková, Veronika...... P168,P248 Zoccali, Michele...... P217 X Zou, Hai...... P154 Xavier, Maria Paula DP...... O47,P37 Zubala, Marta...... O36 Xue, Elisabetta...... O40 Zucker, Mark...... P42 Zunec, Renata...... P22,P96,P111,P183,P193,P242 Zvonkov, Eugene E...... P77 Y Yahel, Anat...... P95 Yakutik, Igor A...... P77 Yang, Jianxin...... O43 Yang, Soo Young...... P123,P138 Yang, Ya-Chien...... P72 Yankova, Petiya...... P20 Yasmill, Ramirez...... P92
117 nd EUROPEAN IMMUNOGENETICS AND HISTOCOMPATIBILITY CONFERENCE ART AND SCIENCE: THE EVOLVING PICTURE 32 OF IMMUNOGENETICS
JOINT CONFERENCE EFI-AIBT
25th Annual Meeting of the Italian Society for Immunogenetics and Transplantation Biology (AIBT) VENICE LIDO, MAY 9-12, 2018
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