Understanding the Real-World Cost and Burden of Mania: the MANACOR Study Hidalgo-Mazzei D., M.D
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Mitochondrial Dysfunction in a Family with Psychosis and Chronic Fatigue Syndrome
ÔØ ÅÒÙ×Ö ÔØ Mitochondrial dysfunction in a family with psychosis and chronic fatigue syndrome Helena Torrell, Yolanda Alonso, Gl`oria Garrabou, David Mulet, Marc Catal´an, Alba Valiente-Pallej`a, Lidia Carre˜no-Gago, Elena Garc´ıa-Arum´ı, Elena Monta˜na, Elisabet Vilella, Lourdes Martorell PII: S1567-7249(16)30221-5 DOI: doi:10.1016/j.mito.2016.10.007 Reference: MITOCH 1139 To appear in: Mitochondrion Received date: 11 December 2015 Revised date: 7 July 2016 Accepted date: 26 October 2016 Please cite this article as: Torrell, Helena, Alonso, Yolanda, Garrabou, Gl`oria, Mulet, David, Catal´an, Marc, Valiente-Pallej`a, Alba, Carre˜no-Gago, Lidia, Garc´ıa-Arum´ı, Elena, Monta˜na, Elena, Vilella, Elisabet, Martorell, Lourdes, Mitochondrial dysfunc- tion in a family with psychosis and chronic fatigue syndrome, Mitochondrion (2016), doi:10.1016/j.mito.2016.10.007 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. ACCEPTED MANUSCRIPT Torrell et al, 1 de 42 Word count: 5190 Article title: Mitochondrial dysfunction in a family with psychosis and chronic fatigue syndrome Authors: Helena Torrell a§, Yolanda Alonso b, Glòria Garrabou c, David Mulet b, Marc Catalán c, Alba Valiente-Pallejà b, Lidia Carreño-Gago d, Elena García-Arumí d, Elena Montaña a, Elisabet Vilella a, Lourdes Martorell b§* Affiliations: a Centre for Omic Sciences, Centre Tecnòlogic de Nutrició i Salut. -
Biological Processes Modulating Longevity Across Primates
Biological Processes Modulating Longevity across Primates: A Phylogenetic Genome-Phenome Analysis Gerard Muntane,*,1,2 Xavier Farre,1 Juan Antonio Rodrıguez,3 Cinta Pegueroles,4,5 David A. Hughes,6,7 Jo~ao Pedro de Magalh~aes,8 Toni Gabaldon, 4,5,9 and Arcadi Navarro*,1,4,5,9 1 Institute of Evolutionary Biology (UPF-CSIC), Universitat Pompeu Fabra, Barcelona, Catalonia, Spain Downloaded from https://academic.oup.com/mbe/article-abstract/35/8/1990/5000154 by Biblioteca de la Universitat Pompeu Fabra user on 21 September 2018 2Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, Biomedical Network Research Centre on Mental Health (CIBERSAM), Reus, Spain 3CNAG-CRG, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain 4Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain 5Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain 6Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom 7MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom 8Integrative Genomics of Ageing Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom 9Institucio Catalana de Recerca i Estudis Avanc¸ats (ICREA), Barcelona, Spain *Corresponding authors: E-mails: [email protected], [email protected]. Associate editor:GregoryWray Abstract Aging is a complex process affecting different species and individuals in different ways. Comparing genetic variation across species with their aging phenotypes will help understanding the molecular basis of aging and longevity. Although most studies on aging have so far focused on short-lived model organisms, recent comparisons of geno- mic, transcriptomic, and metabolomic data across lineages with different lifespans are unveiling molecular signatures associated with longevity. -
Eduard Vieta Is Professor of Psychiatry, Head of The
Eduard Vieta is Professor of Psychiatry at the University of Barcelona and Chair of the Department of Psychiatry and Psychology at the Hospital Clinic, where he also leads the Bipolar Disorders Program in Barcelona, Catalonia, Spain. The Bipolar Unit is one of the worldwide leaders in clinical care, teaching and research on bipolar disorder. Dr. Vieta is the current Director of the Bipolar Research Program at the Spanish Research Network on Mental Diseases (CIBERSAM), funded by the Spanish Ministry of Economy and Competitiveness. Professor Vieta has received several awards, including the Aristotle award (2005), the Mogens Schou award (2007), the Strategic Research award of the Spanish Society of Biological Psychiatry (2009), the Official College of Physicians award to Professional Excellence (2011), the Colvin Price on Outstanding Achievement in Mood Disorders Research by the Brain and Behaviour Research Foundation (2012), and the Clinical Neuroscience Lilly award by the International College of Neuropsychopharmacology (CINP 2014). He is currently the treasurer of the European College of Neuropsychopharmacology (ECNP). He has made significant contributions to many of the published bipolar disorder treatment guidelines and has authored more than 500 original articles, 350 book chapters and 30 complete books. His H index is 70 and has over 18000 citations, which makes him the most cited scientist worldwide in the field of bipolar disorder over the last 5 years and one of the world’s most influential scientific minds, according to Thompson Reuters. Furthermore, he is on the editorial board of a range of international scientific journals and has served as invited professor at McLean Hospital and Harvard University and as neuroscience scientific advisor to the European Presidency. -
The International Consortium Investigating Neurocognition in Bipolar Disorder (ICONIC‐BD)
DOI: 10.1111/bdi.12748 EDITORIAL The International Consortium Investigating Neurocognition in Bipolar Disorder (ICONIC‐BD) Bipolar disorder (BD) is the fourth leading cause of disability world‐ are associated with more pronounced cognitive impairment indica‐ wide among young people of age range 10‐24 years. Although the tive of a neuroprogressive course; however, each individual study has diagnosis is largely defined by the mood episodes associated with been small and thereby unable to address specific questions such as the illness, cognitive deficits are among the most persistent and dis‐ whether the polarity of prior episodes, duration of illness, or medica‐ abling symptoms of illness and have a profound impact on clinical tion effects are relevant to cognitive outcome. Interestingly, very few course and functional outcome. Specifically, trait‐like impairment is studies have adequately addressed one of the most basic questions common in the domains of attention, verbal learning, and executive in BD—how does current symptom severity affect the nature and ex‐ function; these deficits contribute to functional disability and are tent of cognitive impairment and is this a bidirectional effect? Many targets for emerging treatments and preventions. Although consid‐ other illness‐related factors are likely to contribute to cognitive and erable progress has been made over the past two decades, our un‐ functional outcomes in BD (eg, sleep, obesity, comorbid medical and derstanding of the underlying causes of the cognitive deficits in BD psychiatric -
El Modernisme, Domènech I Montaner I El Seu Temps
. ISBN: 978-84-946247-4-2 112 HISTORIOGRAFIA DE REUS P. ANGUERA, J. MASSÓ, E. GORT, E. PEREA , M. FERRAN, J. NAVAIS Jornades d’arquitectura modernista 113 EL GUAITA – Articles periodístics CLAUDI ARNAVAT CARBALLIDO 114 PERE CAVALLÉ, CIUTADANIA REPUBLICANA XAVIER FERRÉ TRILL 115 UN DESIG POLÍTIC I UNS DELICTES POPULARS. L’AUDIÈNCIA CRIMINAL DE REUS El Modernisme, ALBERTO DIAZ FOZ 116 COMPLEMENTS CIRCUMSTANCIALS PERE ANGUERA NOLLA 117 BLOC DE TREBALL Domènech i Montaner SALVADOR JUANPERE 118 150 AUTÒGRAFS FONS CENTRE DE LECTURA LLIBRE DE SIGNATURES i el seu temps 119 LES CIUTATS DEL MÓN JOSEP IGLÉSIAS I ALTRES 120 HISTÒRIA DE REUS A TRAVÉS DEL BALL ALEIX CORT 121 AL COR DE LA MUNTANYA JOSEP CORNUDELLA 122 TRESCANT PER LA VIDA RAFEL FERRÉ MASIP 123 GOSAR PODER, SEMINARI GABRIEL FERRATER JORDI JULIÀ, XAVIERA MORÓS, RAMON GOMIS, JOSEP MURGADES, FINA MASDÉU 124 L’ENLLUMENAT PÚBLIC A LA CIUTAT DE REUS (1855-1965). DELS FANALS DE GAS A LES LÀMPADES ELÈCTRIQUES FLORENTÍ MOYANO I JIMÈNEZ 125 LA CRISI DE 1929 A REUS I COMARCA JOSEP BERTRAN CUDERS 126 INVASIÓ SUBTIL GUILLEM LATORRE 127 PREMSA I SOCIETAT 128 ERNEST CASAJUANA, POESIA I TEATRE ALBERT VENTURA 129 HISTÒRIES DEL SEGON PIS Taller d’escriptura del Centre de Lectura 130 UNA APOSTA NOVIOLENTA PER A LA PAU Trenta anys de Memorial Josep Vidal i Llecha 131 JORNADES D’ECONOMIA: CRISI ECONÒMICA I SOCIETAT. L’IMPACTE EN EL NOSTRE TERRITORI 132 LA LITERATURA COM A PATRIMONI I DESENVOLUPAMENT DEL TERRITORI TEMPS SEU I EL MODERNISME, DOMÈNECH I MONTANER EL 133 JORNADES LLIBRE ANTIC. LLIBRE ANTIC: MEMÒRIA DEL PASSAT Coordinadors 134 LA SARDANA BALLADA A REUS 135 UNS I ALTRES. -
1 L'hopital De La Santa Creu I De Sant Pau À Barcelona
L’HOPITAL DE LA SANTA CREU I DE SANT PAU À BARCELONA. PASSÉ, PRÉSENT ET FUTUR. Esther Balasch, Historienne de l’Art & Montserrat Caldés, Hôpital de la Santa Creu i de Sant Pau, Barcelona Lluís Domènech i Montaner Lluís Domènech i Montaner (1849-1923) est l’architecte des deux grands centres hospitaliers du modernisme (ou Art nouveau) catalan dont nous allons traiter au cours de cette conférence. Diplômé en sciences exactes, physiques et naturelles, il obtint en 1973 son titre d’architecte et se consacra à cette profession, ainsi qu’à l’enseignement à l’École d’Architecture, pendant 45 ans. Activiste politique, historien de l’art et homme de son temps, ses connaissances et études en minéralogie, zoologie et botanique sont déterminantes pour comprendre, en partie, l’ornementation de l’ensemble monumental de l’Hôpital de la Santa Creu i Sant Pau , qui constitue le complexe hospitalier le plus grand conçu en langage moderniste, avec l’Institut Pere Mata de Reus. Ce dernier, créé antérieurement par le même architecte, en 1897, sera le prédécesseur du futur HSCSP de Barcelone avec des réminiscences d’autres oeuvres de caractère civile, telles que le Palau de la Música Catalana de Barcelone. Institut Pere Mata de Reus L’Institut Pere Mata de Reus (Tarragone), dont le fondateur est le Dr. Emili Briansó Planas (1861-1922), occupe un terrain de 20 hectares et il est exclusivement réservé aux maladies mentales. À travers ce nouvel ensemble hospitalier, le Dr. Briansó Planas visait à réformer l’Hôpital psychiatrique de la province de Tarragone dans le but d’offrir une assistance adéquate aux personnes souffrant de maladies mentales diverses. -
Medical List
U.S. Consulate General Paseo Reina Elisenda 23 – 08034 Barcelona, Spain Tel: (34) 93-280-2227 – Fax: (34) 93-280-6175 Email: [email protected] Web Site: https://es.usembassy.gov/embassy-consulates/barcelona/ _________________________________________________________________________________________________________________________________ Medical List This list is prepared by the Consular Section of the Consulate General of the United States of America in Barcelona, Spain. This list covers the U.S. Consulate General’s consular district consisting of: The Autonomous Community of Catalonia; Provinces of Barcelona, Lleida, Tarragona and Girona, The Autonomous Community of Aragon; Provinces of Zaragoza, Huesca and Teruel, and the Principality of Andorra. DISCLAIMER: The U.S. Consulate General in Barcelona, Spain assumes no responsibility or liability for the professional ability or reputation of, or the quality of services provided by, the medical professionals, medical facilities or air ambulance services whose names appear on the following list. Inclusion on this list is in no way an endorsement by the Department of State or the U.S. Consulate General. Names are listed alphabetically, and the order in which they appear has no other significance. The information in the list on professional credentials and areas of expertise is provided directly by the medical professional, medical facility or air ambulance service; the Consulate General is not in a position to vouch for such information. You may receive additional information about the individuals and facilities on the list by contacting local medical boards and associations (or its equivalent) or local licensing authorities. Good medical care is available in Spain. However, regulations regarding medications vary from those in the United States. -
The International Consortium Investigating
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Newcastle University E-Prints DR. KATHERINE BURDICK (Orcid ID : 0000-0003-4417-4988) DR. CHRISTOPHER BOWIE (Orcid ID : 0000-0002-1983-8861) DR. ANDRE CARVALHO (Orcid ID : 0000-0001-5593-2778) DR. LARS KESSING (Orcid ID : 0000-0001-9377-9436) DR. BENY LAFER (Orcid ID : 0000-0002-6132-9999) DR. KATHRYN EVE LEWANDOWSKI (Orcid ID : 0000-0003-1477-6187) DR. ANABEL MARTINEZ-ARAN (Orcid ID : 0000-0002-0623-6263) PROF. ROGER S MCINTYRE (Orcid ID : 0000-0003-4733-2523) DR. KAMILLA WOZNICA MISKOWIAK (Orcid ID : 0000-0003-2572-1384) PROF. RICHARD PORTER (Orcid ID : 0000-0002-8695-3966) DR. TAMSYN VAN RHEENEN (Orcid ID : 0000-0003-3339-6665) Article Article type : Editorial The International Consortium Investigating Neurocognition in Bipolar Disorder (ICONIC-BD) Katherine E. Burdick, PhD1*, Caitlin E. Millett, PhD1, Caterina del Mar Bonnín PhD2, Christopher Bowie, PhD3,4, Andre F. Carvalho, MD, PhD3,4, Lisa T Eyler, PhD5,6, Peter Gallagher, PhD7, Philip Harvey, PhD8, Lars Vedel Kessing, MD, DMSc9,10, Beny Lafer, MD, PhD11, Scott A. Langenecker, PhD12, Kathryn E. Lewandowski, PhD13, Carlos López- Jaramillo, MD, MSc, PhD14, David F. Marshall, PhD15, Anabel Martinez-Aran, PhD2, Melvin McInnis, MD15, Roger McIntyre, MD, FRCPC16, Kamilla W. Miskowiak, PhD9,10, Richard J. Porter, MD17, Scot Purdon PhD18, Kelly A Ryan, PhD15, Tomiki Sumiyoshi, MD, PhD19, Ivan J. Torres, PhD20, Tamsyn E Van Rheenen, PhD21,22, , Eduard Vieta, MD, PhD2, Neil Woodward, PhD23 Lakshmi N. Yatham, MBBS, DPM, FRCPC, MBA20, Allan Young, MB ChB, MPhil, PhD, FRCP (Edin), FRCPsych, FRCP(C), FRSB24, 25 1- Brigham and Women’s Hospital – Harvard Medical School, Boston, MA, USA 2- Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. -
A Non-Interventional Naturalistic Study of the Prescription Patterns of Antipsychotics in Patients with Schizophrenia from the Spanish Province of Tarragona
RESEARCH ARTICLE A Non-Interventional Naturalistic Study of the Prescription Patterns of Antipsychotics in Patients with Schizophrenia from the Spanish Province of Tarragona Ana M. Gaviria1☯, José G. Franco1☯*, Víctor Aguado2, Guillem Rico2, Javier Labad1, Joan de Pablo1, Elisabet Vilella1 1 Hospital Universitari Institut Pere Mata, Universitat Rovira i Virgili, CIBERSAM, IISPV Reus, Spain, 2 Hospital Universitari Institut Pere Mata, Reus, Spain ☯ These authors contributed equally to this work. * [email protected] Abstract OPEN ACCESS Citation: Gaviria AM, Franco JG, Aguado V, Rico G, Labad J, de Pablo J, et al. (2015) A Non- Background Interventional Naturalistic Study of the Prescription The analysis of prescribing patterns in entire catchment areas contributes to global mapping Patterns of Antipsychotics in Patients with Schizophrenia from the Spanish Province of of the use of antipsychotics and may improve treatment outcomes. Tarragona. PLoS ONE 10(10): e0139403. doi:10.1371/journal.pone.0139403 Objective Editor: Peter John McKenna, Benito Menni Complejo To determine the pattern of long-term antipsychotic prescription in outpatients with schizo- Asistencial en Salud Mental, SPAIN phrenia in the province of Tarragona (Catalonia-Spain). Received: April 27, 2015 Accepted: September 10, 2015 Methods Published: October 1, 2015 A naturalistic, observational, retrospective, non-interventional study based on the analysis Copyright: © 2015 Gaviria et al. This is an open of registries of computerized medical records from an anonymized database of 1,765 access article distributed under the terms of the patients with schizophrenia treated between 2011 and 2013. Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any Results medium, provided the original author and source are credited. -
Pros and Cons of Specialised Care in Bipolar Disorder: an International Perspective{ Eduard Vieta
The British Journal of Psychiatry (2013) 202, 170–171. doi: 10.1192/bjp.bp.112.118588 Editorial Pros and cons of specialised care in bipolar disorder: an international perspective{ Eduard Vieta Summary Declaration of interest Highly specialised care may have both pros and cons. E.V. leads a specialist bipolar disorder care unit at a public Centralised expert treatment may be more effective than university hospital in Catalonia, Spain. standard community care for bipolar disorder. Rather than trying to solve the false dichotomy between specialised v. community care, the rational integration of both approaches may enhance quality of care and cost-effectiveness. specialised-care settings for a given condition or technique. Eduard Vieta is Professor of Psychiatry, Head of the Department and the Specialisation may be cost-effective in the public sector as long Director of the Bipolar Disorders Program of the Hospital Clinic at the University of Barcelona in Catalonia, Spain. He is the current Director of the as the most appropriate level of care (i.e. tertiary v. community) Bipolar Research Program at the Spanish Research Network on Mental is provided for a given case. Psychiatry may be especially Diseases (CIBERSAM). His research focuses on the neurobiology, vulnerable to some policies that downgrade the importance of epidemiology and treatment of bipolar disorder. medical skills, including diagnosis, treatment and monitoring. In many instances, this has resulted in services that are better suited to delivering non-specific, psychosocial support rather than a process of thorough, broad-based diagnostic assessment with Specialisation in psychiatry formulation of aetiology, diagnosis and prognosis followed by specific treatments aimed at recovery with maintenance of Specialisation is inherent to the progress of medicine. -
Die Top-5 Sehenswürdigkeiten Von Reus
1 Katalonien Tourismus Reus Eva Hakes · Friday, June 28th, 2019 Überblick Es gibt viele Anlässe, für einen Ausflug nach Reus. Der Klassiker unter den Beweggründen für einen Besuch der Geburtsstadt Antoni Gaudís ist Regenwetter in nahegelegenen Strandurlaubs-Orten wie Cambrils oder Salou. Selbstverständlich ist schlechtes Strandwetter ein legitimer Grund sich der Kultur zu widmen. Allerdings lohnt ein Besuch der Stadt Reus sich definitiv auch bei strahlendem Sonnenschein. Das Institut Pere Mata ist eines der Highlights von Reus © Ajuntament de Reus Reus, die Stadt des Modernisme Reus hütet etwa 80 beeindruckende modernistische Bauwerke. 29 von ihnen sind Teil der Modernisme-Route von Reus. Interessanterweise stammt keines dieser Bauwerke vom in Reus geborenen Gaudí, der in so unnachahmlicher Weise Barcelona geprägt Katalonien Tourismus - 1 / 10 - 02.07.2021 2 hat. Dafür finden sich hier u.a. Werke von Domènech i Montaner, die zu den Höhepunkten der modernistichen Architektur Kataloniens zählen. Zu diesen gehören zum Beispiel die Casa Navàs und das Institut Pere Mata, ein Vorläufer des berühmten Hospital de Sant Pau in Barcelona, das zum Unesco-Welterbe zählt. Neben Bauwerken von Domènech i Montaner kann man auf der Modernisme-Route auch den katalanischen Jugendstil in seiner Ausprägung durch Architekten wie Pere Caselles und Joan Rubió i Bellver kennenlernen. Detail der Casa Navàs an der Plaça del Mercadal © Miguel Raurich Während Gaudí zu Beginn des 20. Jahrhunderts in Reus offenbar weit weniger Anerkennung erhielt als seine Kollegen, hat ihm seine Heimatstadt zu Beginn des 21. Jahrhunderts ein grandioses Denkmal gesetzt. Das 2007 eröffnete Gaudí Centre gewährt mit einem multimedialen und multisensorialen Ansatz faszinierende Einblicke in das Leben und Schaffen des Ausnahme-Architekten. -
Mosaic and Trencadís in the Palau De La Música Catalana Cristina Martí Robledo A*
Available online at www.IJournalSE.org Emerging Science Journal Vol. 2, No. 2, April, 2018 Mosaic and Trencadís in the Palau De La Música Catalana Cristina Martí Robledo a* a Restauracions POLICROMIA SL, Catalonia Abstract Keywords: Modernism has provided Catalonia with buildings of great artistic value, such as the Palau de la Música Modernisme; Catalana located in the heart of Barcelona. Its architect, Lluís Domènech i Montaner, approached Lluís Domènech i Montaner; ornamentation as a thorough integration of arts and crafts: ceramic is treated as the ¨key¨ element, Conservation; decorating the entire building while coating and protecting its internal metallic structure at the same Restauration. time. During Modernisme, the classic mosaic technique, based on the use of small tiles (or tesserae) made Article History: of ceramics or glass paste, incorporated a new method called trencadís (A procedure carried out using irregular pieces of tiles fragmented randomly and put together in an abstract way). Received: 20 March 2018 Accepted: 01 May 2018 1- Introduction In the heart of Barcelona's old town (Ciutat Vella) lies the emblematic Palau de la Música, a building from the Modernista era, which was declared a BCIN (Heritage Site of National Interest) in 1971 and UNESCO World Heritage Site in 1997. (Figure 1). It is located on the junction of the streets Sant Pere més Alt, Amadeus Vives and Sant Francesc de Paula, where there once stood a Convent with the same name, and which in 1992 was knocked down. Its architect, Lluís Domènech i Montaner was one of a series of great names that the Modernista era produced.