N. I. H.

U. S. DEPARTMENT OF PUBLIC HEALTH SERVICE HEALTH, EDUCATION, AND WELFARE May 14, 1956 - Vol. VIH, No. 9 NATIONAL INSTITUTES OF HEALTH HAMSTERS TO PRESENT 6th "LIFE AT NIH" SHOW The annual Hamster show, "Life at NIH," will be presented on May 24, 25, and 26, at 8:30 p.m. in the CC Auditorium. Tickets, priced at $1.10 each, are now on sale at the CC lobby desk or may be obtained fromR&W Division Representatives.

This year's presentation comes to life under the title of "Health's a-Poppin" and includes a cast of over 50. The show is under the direction of Dr. Richard Williams, and the script was written by Judson Hardy. There will be Spanish dances, a Hawaiian, scene complete with Ha­ waiian dancers from the NIH res­ ervation, and a variety of othar acts. Dr. Scheele addresses an overflow crowd at the awards ceremony in Wilson Hall. 394 EMPLOYEES HONORED AT ANNUAL AWARDS CEREMONY In the largest annual awards cere­ An award of $250 went to Mrs. The Follow-Up Unit of the SMB mony in NIH's history, a total of 48 Mollie P. Breyere, passenger and Procurement Section won a $395 employees received $6360 in Supe­ traffic clerk, for her unusually suc­ group award for its efficient work in rior Performance Awards, while cessful record of efficient travel promoting the prompt delivery of all five were honored for 30 years' planning for NCI scientists. Another materials and equipment ordered at Government service, 44 for 20 $250 was awarded to Mr. Harry W. NIH. A $700 award went to the Dupli­ years' .service and 297 for 10 years' Diehl, physical aide, for his cating Unit of the DRG Administra­ service. The ceremony, which was discovery of new chemical com­ tive Services Section for the swift held in Wilson Hall on May 4, was pounds of importance to the NIAMD and superior work it does at NIH's highlighted by addresses by Laboratory of Chemistry. Mr. printing plant. The fourth Superior Mr. Bradshaw Mintener, Chairman George Sklar, supervisory auditor, Performance Group Award was a of the DHEW Board on Employee DRG, was also the recipient of a $250 $1300 check for the CC Clinical Pa­ Awards, and Surgeon General award for outstanding efficiency in thology Department, which was cited Leonard A. Scheele. Mr. Scott administration of the field audit of for its remarkable record in the con­ Adams, Chairman, NIH Board on the research grants program. An duct and development of the testing Employee Awards, presided over the award of $215 went to Mr. Israel procedures which service all CC ceremony, and the awards were pre­ Light, NCI information specialist, clinical professions. sented by Dr. C. J. Van Slyke, NIH for his organization of a highly suc­ Helen S. Dalrymple and Lloyd M. Associate Director. cessful all-day meeting of science Runkle, DRS, were honored for 30 teachers at NIH. years of Government service. Other Seven employees received indi­ NIH 30-year award winners were vidual Superior Performance A Superior Performance Group James F. O'Donnell, Frederick B. Awards ranging from $500 to $215. Award was presented to the Unit on Thrailkill, and Ray E. Willey, of Three awards of $500 each were Amino Acid Production and Nutrition Hamilton, Mont. presented to Mr. John E. Fletcher, of the NCI Laboratory of Biochemis­ Recipients of the 20-year awards OD, Dr. Milton Winitz, NCI, and try, which was cited for extraordi­ were William G. Baylis, Mary D. Dr. Harold P. Morris, NCI, all nary accomplishment in the produc­ Bertha, C. Lee Bowen, Lynda Lee recent winners of DHEW Superior tion of large quantities of amino Cahoon, Paul T. Calderwood, Service Awards. acids for use by NCI scientists. (See Awards, Page 31 Studies of 'Drugs on Publication Preview

Certain Psychological Junctions The following manuscripts were received by the SRB Editorial Section between April 14 No. 162 in a Series and April 30. Anderson, George S. A comprehensive attack on cerebral palsy. Anfinsen, C B., Jr. Biochemical aspects of atherosclerosis. Arnold, F. A., Jr., etal. Effect of fluoridated public supplies on dental caries prev­ alence. II. Summary results of the tenth year of the Grand Rapids-Muskegon study. Bell, J. Frederick, et al. A polyvalent toxoid for botulism in mink. Blough, Donald S. Some effects of drugs on visual discrimination in the pigeon. Davis, Gordon E., et al. Observations on the biology of the argasid tick Ornithodoros foleyi Parrot, 1928 (Ixodoidea, Argasidae). Dorn, Harold F. Cancer of the liver, infec­ tious hepatitis and cirrhosis of the liver in the . Drage, G. A., et al. Diseases of the muscles. Dunn, John E., et al. The usefulness of wr death certificate statement of occupation in comparing mortalities. Dunn, John E., et al. Excess lung cancer mor­ tality rates among Mexican women in California. Eagle, Harry. The nutritional requirements for the propagation of poliomyelitis virus by the HeLa cell. Miss Ogretta Humphries, Psychologist, runs visual perception test on patient. Emmons, Chester W. Silver in the treatment of experimental cryptococcosis. A study is being conducted in of the subjects when they received Emmons, Chester W. Epidemiology of the NIMH to determine the effects of a the secobarbital, chlorpromazine, mycoses. Fish, M. S., et al. Studies on hallucinogenic variety of drugs on humans. In these and LSD. Secobarbital, however, snuffs. studies, chlorpromazine, LSD, me­ produced greater impairment than Foltz, Calvin M., et al. The stereochemistry peridine, and secobarbital have been chlorpromazine, although not statis­ of the l-phenyl-l,2-propanedio!s and of d- used to determine their psychologi­ tically significant. In no individual isoephedrine. test was impairment of performance Fouts, J. R., et ai. Some mechanisms of drug cal effects on normal adults. potentiation. caused by secobarbital significantly Frank, Karl, et al. Electrical properties of The double-blind technique, where greater than that of chlorpromazine. spinal motoneurones. neither the subject nor the person Meperidine, at the dosages used, Gay, William I. Prosthetic replacement of the running the tests knows which drug is did not significantly impair psycho­ mid shaft of the radius of the dog. being administered, is being em­ Gay, William I. Recently developed orthopedic logical functioning. operations applicable to canine practice. ployed in these tests. In addition, it was found that the Gibson, Colvin L. Comparative results of the subject who was most affected by one dye test for toxoplasmosis in an urban and a After the drugs are administered drug was often the one most affected rural Negro population. orally, the patients, who are normal Haenszel, William, et al. A proposed study by the other drugs. for extending the scope and improving the volunteers, are kept on the ward for Dr. Conan H. Kornetsky and Miss quality of mortality data. study. Observations are then made Ogretta A. Humphries, both of NIMH, Hayes, Richard L., et al. Clinical and roent- and findings recorded by ward have been conducting these studies. genographic determination of dental caries ex­ nurses. Normally, the effects of the perience of school children in Grand Rapids, Plans are now under way to con­ Michigan. drugs last approximately six hours. tinue studies of this nature in the Hill, Borroughs R., et al. The sedimentation Each patient receives the drug at two field of stimulant drugs and to com­ behavior of serum lactic dehydrogenase. separate intervals — once at low pare findings with those of depres­ Hill, Harris E., et al. Motivational determi­ dosage and once at high dosage. The sant drugs. Alsoprojectedisastudy nants in the pharmacological modification of results of the tests have indicated behavior: morphine and . on the relation between individual Horecker, B. L., et al. The role of xylulose that chlorpromazine has as much ef­ responsiveness to drugs and 5-phosphate in the transketolase reaction. fect as secobarbital, but neither drug personality. Hueper, W. C. Experimental carcinogenic has any residual effect. The tests studies in macromolecular chemicals. I. Neo­ are run over a period of two months, plastic reactions in rats and mice following par­ a total of ten tests per person during enteral introduction of polyvinyl pyrrolidones. Hurwitz, Jerard, et al. The purification of that period. phosphoketopentoepimerase from Lactobacillus N. I. H. RECORD pentosus and the preparation of xyluose 5- phosphate. The tests include intellectual, mo­ Kelman, Herbert C. Three processes of ac­ tor coordination and perceptual Published by ceptance of social influence: compliance, iden­ tests. The total time necessary to Scientific Reports Branch tification and internalization. complete all tests is approximately National Institutes of Health Korn, Edward D., et al. Enzymic degradation 90 minutes. Test analyses re­ of heparin. Room 111, Building 1 Li, Choh-lu, et al. Some properties of dener- vealed that there is statistically sig­ Bethesda 14, Maryland vated muscles recorded with intracellular elec­ nificant impairment in performance OLiver 6-4000 Ext. 2125 trodes. Liddle, Grant W., et at. Studies of structure- function relationships of steroids: the 2-methyl Lost and Found corticosteroids. MJt Spotlight Mehler, Alan H., et al. Studies with carboxyl- The following articles have been labeled 3-hydroxyanth rani lie and picolinic found on the NIH reservation and may acids in vivo and in vitro. be seen in the Guard Office, Room Mider, G. Burroughs. Some developments in cancer research. 1A-06, Building 10. Nadel, Eli, et al. Comparative effects of Assorted gloves Galoshes ACTH and LSD on urinary corticosteroids in Earrings Scarves guinea pigs. Eyeglasses Woman's jacket Omata, Robert R., et al. A selective medium for oral fusobacteria. Belts Umbrellas Parrott, Robert H. APC viruses in respiratory Fountain pens Cigarette lighter diseases ~ clinical aspects. Keys Redl, Fritz. What makes children misbehave? Richtmyer, Nelson K., et al. Sedoheptulose - its rotation, reducing power, equilibrium with sedoheptulosan in acid solution, and crystalline GUARD OF THE MONTH hexaacetate; also crystalline 2,7-anhydro-8-D- A ready willingness to comply with altro-heptulofuranose. suggestions and orders and an initia­ Schaefer, Earl $., et al. Quantification of tive to follow through on his own has maternal behavior and consistency of mother- brought Kenneth Startin of the Guard child interaction. Scheer, Irving, et al. 5-cholesen-38, 26-diol. Section the honor of Guard of the Shimkin, Michael B., et al. Survival in un­ Month. treated and treated cancer. Corporal Startin joined the NIH Schmid, Rudi. Bilirubin glucuronide,-the di­ Catherine Roelkey Guard Force in 1955 after serving rect reacting bilirubin, in serum, bile, and urine. The job undertaken by the social Schwartz, Charlotte G. Aspects of society in with a county government in Vir­ the rehabilitation process— the stigma of mental worker in a medical setting is a dif­ ginia. From 1936 until 1952 he had illness. ficult and challenging one. For each served with the Army and Air Force Sokoloff, Louis. Factors regulating the total individual case, she mustdrawupon as a motor transportation supervi­ and regional circulation of the brain. her knowledge of people and how they sor and was honorably discharged Tallent, W. H., et al. Hie structure of can be helped, of community re­ pinidine. with the rank of Master Sergeant. Vivian, Donald L. The practical synthesis of sources, and of the particular medi­ He was born in Salt Lake City, Utah, 1-phenazinol. cal problem with which her patient where he attended school. Vivian, Donald L., et al. Reactions of 2- is faced. In all cases, she must nitrodiphenyl sulfide and related sulfones in respect the patient's "right of self- attempted ring closure. Westfali, B. B., et al. Effect of glutamtne on determination" and help him to reach Kay brings a rich background of the growth and metabolism of liver cells in vitro. his own solution to his problems. training and experience to her pres­ Witkop, Bernhard, et al. Studies in the Such an assignment is held down by ent task. She received her under­ stereochemistry of *P-ephedrine. blonde, attractive Kay Roelkey, pro­ graduate training in sociology at Wood, Harry B., Jr., et al. Some products gram supervisor of Cancer Social Seton Hill College in Greensburg, arising from the condensation of D-ribose with benzaldehyde 2,3-o-benzylidene-8-D-ribofura- Service. Pa., and her master's degree in nose and di-(2,3-0-benxylidene-D-ribofuranose)- psychiatric social work at Catholic 1,5': V5-dianhydride. The problems with which Kay and University. For two and a half years, Wood, John W. An electrically heated and her staff of three caseworkers are she served as medical social worker thermostatically controlled oil bath. concerned are the personal, social, with the Red Cross at Fort Benjamin Wyckoff, R. S. G. Viruses and macromolecules or economic difficulties that ac­ studied with the electron microscope and ultra- Harrison and Fort Lee. After a stint centrifuge. company any kind of long-term ill­ at Mercy Hospital in Pittsburgh, she Wynne, C. Lyman, et al. Family relationships ness. In some cases they may have switched to psychiatric social work of schizophrenic patients: a "rubber fence" to deal with the patient's emotional and spent three years in this field at hypothesis. attitude toward his own illness, or Walter Reed Army Hospital before Yagoda, H. Frequency of thindown hits by arrange day care for members of the heavy primary nuclei in emulsion and tissue. coming to NIH in 1954. patient's family, or help prepare him for problems he may face after his Kay and her four sisters grew up in AWARDS Cont'd discharge. To help solve the prob­ Uniontown, Pa., which is still the lem, Kay says, "We attempt to know Roelkey family home.' Born with a Mildred E. Causey, Louise C. Clark, Jacob L. the individual, his culture, to study Craumer, William C. Curtis, Frances C. "wandering foot," she has traveUed Dajrtowski, Bertie E. Dawson, Joseph A. Derbis, his personality, to evaluate the prob­ over most of the Eastern U. S., Robert E. Frazitr, Earl Gillums, Florence B. lem and help the patient move toward Canada, and parts of the West. Next Hall, William 0. Hendershot, Myrtle W. Jones, the best solution for him." Mary M. Kanyuch, Harry J. Knight, Robert E. fall she plans to complete her explo­ Learmouth, Peter J. Lewis, Rebecca M. Lipford, ration of the West with a trip to Harry J. McGahren, Charles E. Mills, Ada Murphy, David D. Murray, Esther J. N'tckerson, At all times, the social worker is California. Other favorite pastimes Helen D. Park, Charles T. Razum, Lois S. functioning as a part of the hospital include swimming, reading, and Romer, Foster J. Rowen, Herbert F. Seversmith, team of doctors, nurses, occupa­ bridge, and she admits to "dabbling Helen B. Smith, Thomas J. Smith, Marvin I. Snell, Curtis Sullivan, Francis S. Taylor, Jr., tional and physical therapists and at golf." Emily E. Trueblood, Donald R.Watson, Roger R. others who come in close daily con­ Wright, and Louise B. Young. Others who re­ tact with the patient. Because she is ceived 20-year awards were Armel K. Thompson In addition, she finds time to serve and Gaiba D. Van Horn of Lexington, Ky., and also serving as a link between the as secretary of the Metropolitan James M. Brennan, of Guatemala City, Guatemala. hospital and the community, she Washington Chapter of the Psychi­ The 297 10-year award winners wHI be hon­ works with the patient's family and ored at separate Institute ceremonies. Also on atric Social Work Section, and as a the awards program was the list of 30 new mem­ often in close cooperation with the member of the Advisory Council of bers of the NIH 1000-Hour Sick-Leave Club. local social agencies. the D. C. Mental Health Association. SUPERIOR PERFORMANCE WON $6360 FOR THESE EMPLOYEES

Pictured here are individual Superior Per­ formance Award winners George Sklar, DRG; Israel Light, KCI; and Dr. Harold Morris, Additional individual Superior Performance winners are John E. Fletcher, OD; Dr. Milton Winitz, NCI. NCI; Mrs. Mollie P. Breyere, NCI; and Harry W. Diehl, NIAMD.

Superior Performance Group Awards were received by the Follow Up Unit of the SMB Procurement Section, the Duplicating Unit of the DRG Administrative Services Section,

and the Unit on Amino Acid Production and Nutrition of the NCI the Clinical Center Clinical Pathology Department, Laboratory of .

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