Human SFRP5 Peptide (DAG-P1162) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

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Human SFRP5 peptide (DAG-P1162) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. [provided by RefSeq, Jul 2008] Nature Synthetic Expression System N/A Purity 70 - 90% by HPLC. Conjugate Unconjugated Cellular Localization Secreted Procedure None Format Liquid Preservative None Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request. ANTIGEN GENE INFORMATION Gene Name SFRP5 secreted frizzled-related protein 5 [ Homo sapiens (human) ] Official Symbol SFRP5 Synonyms SFRP5; secreted frizzled-related protein 5; SARP3; FRP-1b; SARP-3; sFRP-5; frizzled-related protein 1b; secreted apoptosis related protein 3; secreted apoptosis-related protein 3; Entrez Gene ID 6425 mRNA Refseq NM_003015.3 Protein Refseq NP_003006.2 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved UniProt ID Q5T4F7 Chromosome Location 10q24.1 Pathway Wnt signaling pathway, organism-specific biosystem; Wnt signaling pathway, conserved biosystem; Function PDZ domain binding; Wnt-activated receptor activity; Wnt-protein binding; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.

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Hyperactivated Wnt-Β-Catenin Signaling in the Absence of Sfrp1 and Sfrp5 Disrupts Trophoblast Differentiation Through Repressio
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