Digestive system 1 ➢ Oral cavity: • Lips • Tongue • Palate – soft - hard ➢ Tooth Common structure of the wall of GIT tube
• The tunica mucosa – epithelial lining – lamina propria /loose connect. tissue/ – lamina muscularis mucosae • The submucosa (tela submucosa) /loose connect. tissue + Meissner´s nerve plexus/
• The tunica muscularis externa – circular • myenteric nerve plexus – longitudinal smooth muscle • The tunica serosa or adventitia /loose connect. tissue -/+mesothelium/ The oral cavity (the tunica mucosa) The epithelium nonkeratinized stratified squamous ep.
Lamina propria loose connective tissue
The muscularis mucosae is missing!!!
Lam. propria → the submucosa (loose connect. tissue) / periost / muscle
3 functional regions of oral mucosa: • covering - lined with submucosa (lips, cheeks, soft palate, fac. mylohyoidea of the tongue) • masticatory – submucosa is missing, mucosa firmly attached to the periost of the bone, so called mucoperiost (gingiva and hard palate) • specialized – forms papillae (dorsum linguae) Labium oris
External surface - skin hair follicles
Transitional
zone (vermilion) m. orbicularis oris
Mucous gll.labiales membrane Lips (labia)
eleidin
◼The epithelium is somewhat thicker than in other parts of the facial skin. ◼C.t. papilla extend deep into the epithelium and are heavily vascularized. It is the proximity of these vessels to the surface of the epithelium which gives the prolabium it's red appearance (+ presence of protein eleidin). inner surface
lamina propria stratified squamous epithelium Apex linguae dorsum linguae
facies mylohyoidea
gl. apicis linguae - Blandini Tongue - dorsal surface The mucosa – filiform, fungiform, circumvallatae, foliatae pap. (the submucosa is missing! ) aponeurosis linguae
- inferior surface (mylohyoidea) The mucosa – without specific papillae the submucosa!
-papillae = elevations of the oral epithelium and lamina propria slizničního vaziva krytý epitelem jazyka skeletal muscle fibers Apex linguae
lamina propria
tela submucosa
facies mylohyoidea
gl. apicis linguae - Blandini Circumvallatae papillae The epithelial linning – strat.squam.ep. + taste buds secondary papillae Lamina propria – loose connect. tissue +serous (von Ebner) glands- drain into deep grooves
primary papilla Papilla circumvallata (HE)
taste bud
groove
gland duct
gll. gustatoriae (Ebneri) Taste bud
Circular groove Soft palate
Nasal surface Mixed gl. - gll.nasales
aponeurosis palatina- skeletal muscle+connect. tissue
Mucous glands - gll. palatinae,
Oral surface Nasal surface
- ciliated pseudostratif. columnar ep.(metaplasia) basement - gll. nasales (mixed gl.) membrane ?
stratified squam. ep.
duct Oral surface -stratified squamous epithelium
basement membrane ?
duct
gll. palatinae (MUCOUS gl.) Anatomy Tooth Corona dentis (crown) Collum (neck) (dens) Radix (root) Cavum et canalis radicis dentis (pulp cavity) Pulpa dentis Apex radicis dentis Deciduous + foramen apicis radicis dentis (baby) teeth- 20 (apical foramen)
Permanent Alveoli teeth – 28-32 Periodontal ligament radix (root) (membrane) dense connective tissue fibers Tooth ROOT ------CROWN cementum enamel!!!!
dentin
dentinal tubules with odontoblast processes Tooth – (HE) 5x
odontoblasts Enamel is missing!!!
predentin – unmineralized dentin with nerve fibers
pulp with odontoblasts
Dentinal tubules with odontoblast processes B O N E
D P E E N R T I I D N O C N E T M I Periodontal ligament – E U dense connective tissue N M Alveolar bone – woven bone T Gingiva connective tissue U papillae+stratif.squamous ep. M Epithelial attachment of Gottlieb Sulcus gingivalis
Gingiva libera
Gingiva affixa
Epithelial attachment of Gottlieb = epith. of gingiva is GINGIVA bound to the tooth - Stratified squamous enamel epith. - Connective tissue papillae
NO!!! Tunica submucosa 1. Digestive system – I
Slides : 1. Labium oris (HE) 2. Apex linguae (HE) 3. Papilla circumvallata (HE) 5. Palatum molle (HE) 7. Tooth (HE)
Atlas: Development of face (87) Pharyngeal (branchial) apparatus. Development of tongue (88) Development of the face, stomodeum and cervical region – embryo, day 24
body ectoderm
proc. frontonasalis Rathke‘s pouch proc. maxillaris brain stomodeum proc. mandibularis
stomodeum pharyngeal cardiac membrane bulge
perikardiac cavity
forgut chorda A – sagital section dorsalis B – frontal view Development of the face, stomodeum and cervical region – embryo, day 28
proc. nasalis pharyngeal membrane (perforated) med. + lat.
proc. frontalis
Rathke‘s pouch nasal placode
proc. maxillaris chorda dorsalis proc. mandibularis
1st– 4th 2nd and 3rd endodermal branchial arch pouch
pharynx Development of the face – embryo , end of week 5
nasal placode Development of pharyngeal (branchial) apparatus – embryo, week 6
ectomesenchyme
development of tongue endoderm ectoderm
nerve
base of visceral muscles
cartilage eminentia hypobranchialis aortic arch (branchial artery) oesophagus sensitive and motor branches of nerve
pharyngeal (branchial) arches Development of tongue
ectodermal lining
sulcus terminalis
endodermal laryngotracheal diverticle lining (development of respiratory system) thyroid gland
eminentia epiglotic swelling hypobranchialis arytenoid swelling ECTODERMAL CLEFTS and ENDODERMAL POUCHES – embryo, week 5
pharyngeal 1. membrana obturans arches 1-4 membrana tympani
meatus acusticus ext. cavum tympani, tuba (cleft 1) auditiva (Eustachii) sinus (fossa) tonsillaris
gl. parathyreoidea inf.
thymus sinus cervicalis gl. parathyreoidea sup. (clefts 2, 3, 4) ultimobranchial corpuscle Descensus of thyroid gland and thymus with gll. parathyreoideae inf. – embryo, week 6
tongue (k), foramen caecum (i), ductus thyreoglossus (h), gl. thyreoidea(ch), thymus (e), gll. parathyreoideae inf. (d), gll. parathyreoideae sup.(f), ultimobranchial corpuscle (g) Development of palate – embryo, A – week 7, B – week 8, C – week 10
sensory epithelium
septum nasi
nasal cavity
palatine processes
tongue
oral cavity
palatine processes fusion
tongue Development of the oral cavity and teeth – embryo, week 6
upper lip dental lamina + tooth bud
vestibular base of tongue band
lower lip dental lamina + tooth cap cartilago Meckeli ectoderm labium vestibulum dentogingival lamina
primary dental lamina
organ of enamel
permanent tooth
deciduous tooth
dental papilla dentogingival Week 6 – primary dental lamina lamina Week 7-8 – 10 tooth buds (primordia)
deciduous dentition permanent dentition
mandibula or maxilla labial lamina
Developmental stages of tooth 1 2 primary dental lamina
3 1. stage of dental bud (primordium) 2. stage of dental cap 3. stage of dental bell 4. stage of apposition 4 5 5. stage of eruption